WO1994028781A3 - Magnetic resonance arteriography with dynamic intravenous contrast agents - Google Patents

Magnetic resonance arteriography with dynamic intravenous contrast agents Download PDF

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Publication number
WO1994028781A3
WO1994028781A3 PCT/US1994/006223 US9406223W WO9428781A3 WO 1994028781 A3 WO1994028781 A3 WO 1994028781A3 US 9406223 W US9406223 W US 9406223W WO 9428781 A3 WO9428781 A3 WO 9428781A3
Authority
WO
WIPO (PCT)
Prior art keywords
magnetic resonance
contrast agent
contrast agents
intravenous contrast
dynamic
Prior art date
Application number
PCT/US1994/006223
Other languages
French (fr)
Other versions
WO1994028781A2 (en
Inventor
Martin R Prince
Original Assignee
Martin R Prince
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Martin R Prince filed Critical Martin R Prince
Priority to CA002141839A priority Critical patent/CA2141839C/en
Priority to DE69422005T priority patent/DE69422005T2/en
Priority to AU69631/94A priority patent/AU6963194A/en
Priority to EP94918206A priority patent/EP0656762B1/en
Publication of WO1994028781A2 publication Critical patent/WO1994028781A2/en
Publication of WO1994028781A3 publication Critical patent/WO1994028781A3/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/41—Detecting, measuring or recording for evaluating the immune or lymphatic systems
    • A61B5/414—Evaluating particular organs or parts of the immune or lymphatic systems
    • A61B5/416—Evaluating particular organs or parts of the immune or lymphatic systems the spleen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/41—Detecting, measuring or recording for evaluating the immune or lymphatic systems
    • A61B5/411—Detecting or monitoring allergy or intolerance reactions to an allergenic agent or substance
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/18—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/48—NMR imaging systems
    • G01R33/54—Signal processing systems, e.g. using pulse sequences ; Generation or control of pulse sequences; Operator console
    • G01R33/56—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution
    • G01R33/5601—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution involving use of a contrast agent for contrast manipulation, e.g. a paramagnetic, super-paramagnetic, ferromagnetic or hyperpolarised contrast agent
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/48—NMR imaging systems
    • G01R33/54—Signal processing systems, e.g. using pulse sequences ; Generation or control of pulse sequences; Operator console
    • G01R33/56—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution
    • G01R33/563—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution of moving material, e.g. flow contrast angiography
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/20—Measuring for diagnostic purposes; Identification of persons for measuring urological functions restricted to the evaluation of the urinary system
    • A61B5/201—Assessing renal or kidney functions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7271—Specific aspects of physiological measurement analysis
    • A61B5/7285—Specific aspects of physiological measurement analysis for synchronising or triggering a physiological measurement or image acquisition with a physiological event or waveform, e.g. an ECG signal
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/28—Details of apparatus provided for in groups G01R33/44 - G01R33/64
    • G01R33/281—Means for the use of in vitro contrast agents
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/48—NMR imaging systems
    • G01R33/54—Signal processing systems, e.g. using pulse sequences ; Generation or control of pulse sequences; Operator console
    • G01R33/56—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution
    • G01R33/561—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution by reduction of the scanning time, i.e. fast acquiring systems, e.g. using echo-planar pulse sequences
    • G01R33/5619—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution by reduction of the scanning time, i.e. fast acquiring systems, e.g. using echo-planar pulse sequences by temporal sharing of data, e.g. keyhole, block regional interpolation scheme for k-Space [BRISK]
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/48—NMR imaging systems
    • G01R33/54—Signal processing systems, e.g. using pulse sequences ; Generation or control of pulse sequences; Operator console
    • G01R33/56—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution
    • G01R33/563—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution of moving material, e.g. flow contrast angiography
    • G01R33/56308—Characterization of motion or flow; Dynamic imaging

Abstract

This invention is a method of imaging arteries distinctly from veins using nuclear magnetic resonance imaging in combination with intravenous administration of a magnetic resonance contrast agent. The contrast agent is intravenously injected in such a way that the arterial contrast concentration is substantially higher than the venous and background tissue concentration for a sufficiently long period of time to acquire the magnetic resonance image. The injection site of the contrast agent is chosen such that it is in a vein which is remote from the artery of interest. The magnetic resonance contrast agent may be intravenously infused at a variable infusion rate.
PCT/US1994/006223 1993-06-07 1994-06-03 Magnetic resonance arteriography with dynamic intravenous contrast agents WO1994028781A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
CA002141839A CA2141839C (en) 1993-06-07 1994-06-03 Magnetic resonance arteriography with dynamic intravenous contrast agents
DE69422005T DE69422005T2 (en) 1993-06-07 1994-06-03 ARTERIOGRAPHY BY MEANS OF MAGNETIC RESONANCE AND DYNAMIC INTRAVENOUS CONTRASTER INJECTION
AU69631/94A AU6963194A (en) 1993-06-07 1994-06-03 Magnetic resonance arteriography with dynamic intravenous contrast agents
EP94918206A EP0656762B1 (en) 1993-06-07 1994-06-03 Magnetic resonance arteriography with dynamic intravenous contrast agents

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/071,970 US5417213A (en) 1993-06-07 1993-06-07 Magnetic resonance arteriography with dynamic intravenous contrast agents
US08/071,970 1993-06-07

Publications (2)

Publication Number Publication Date
WO1994028781A2 WO1994028781A2 (en) 1994-12-22
WO1994028781A3 true WO1994028781A3 (en) 1995-01-26

Family

ID=22104753

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1994/006223 WO1994028781A2 (en) 1993-06-07 1994-06-03 Magnetic resonance arteriography with dynamic intravenous contrast agents

Country Status (7)

Country Link
US (8) US5417213A (en)
EP (3) EP1345039A1 (en)
AT (2) ATE251310T1 (en)
AU (1) AU6963194A (en)
CA (1) CA2141839C (en)
DE (2) DE69433219T2 (en)
WO (1) WO1994028781A2 (en)

Families Citing this family (173)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5590654A (en) 1993-06-07 1997-01-07 Prince; Martin R. Method and apparatus for magnetic resonance imaging of arteries using a magnetic resonance contrast agent
US5417213A (en) * 1993-06-07 1995-05-23 Prince; Martin R. Magnetic resonance arteriography with dynamic intravenous contrast agents
US5579767A (en) * 1993-06-07 1996-12-03 Prince; Martin R. Method for imaging abdominal aorta and aortic aneurysms
EP0650739B1 (en) 1993-10-28 2003-02-26 Medrad, Inc. Total system for contrast delivery
DE69432582T2 (en) 1993-10-28 2003-11-27 Medrad Inc System for the administration of liquids in several patients
US5494036A (en) * 1993-11-26 1996-02-27 Medrad, Inc. Patient infusion system for use with MRI
US5840026A (en) 1994-09-21 1998-11-24 Medrad, Inc. Patient specific dosing contrast delivery systems and methods
US6397098B1 (en) * 1994-09-21 2002-05-28 Medrad, Inc. Data communication and control for medical imaging systems
US8005530B2 (en) * 1995-04-12 2011-08-23 Prince Martin R Method and apparatus for imaging abdominal aorta and aortic aneurysms
AU5391896A (en) * 1995-04-20 1996-11-07 Invasatec, Inc. Radiographic contrast material injector
US6099502A (en) * 1995-04-20 2000-08-08 Acist Medical Systems, Inc. Dual port syringe
US6221045B1 (en) 1995-04-20 2001-04-24 Acist Medical Systems, Inc. Angiographic injector system with automatic high/low pressure switching
US5882343A (en) * 1995-04-20 1999-03-16 Invasatec, Inc. Dual port syringe
US6656157B1 (en) 1995-04-20 2003-12-02 Acist Medical Systems, Inc. Infinitely refillable syringe
US5687208A (en) * 1995-10-06 1997-11-11 Bhb General Partnership Method of and apparatus for predicting computed tomography contrast enhancement with feedback
US6282513B1 (en) * 1995-10-06 2001-08-28 Glenn G. Strawder Quality assurance method for a machine and an operator
EP0883860B1 (en) * 1996-02-29 2006-08-23 Acuson Corporation Multiple ultrasound image registration system, method and transducer
US5713358A (en) * 1996-03-26 1998-02-03 Wisconsin Alumni Research Foundation Method for producing a time-resolved series of 3D magnetic resonance angiograms during the first passage of contrast agent
US5692508A (en) * 1996-04-15 1997-12-02 Siemens Medical Systems, Inc. Cardiac-gated 3-dimensional MR angiography
US6167293A (en) * 1996-04-19 2000-12-26 General Electric Company Method for performing magnetic resonance angiography using a contrast agent
DE19628951C2 (en) * 1996-07-18 2000-08-31 Juergen Hennig Magnetic resonance imaging method for the time-resolved display of pulsatile vessels (projection angiography)
US5881728A (en) * 1996-07-26 1999-03-16 Wisconsin Alumni Research Foundation Digital subtraction magnetic resonance angiography with image artifact suppression
US5846202A (en) * 1996-07-30 1998-12-08 Acuson Corporation Ultrasound method and system for imaging
DE19647701A1 (en) * 1996-11-08 1998-05-14 Schering Ag Device for obtaining constant densities of contrast media in tissues and organs
US5851184A (en) * 1996-11-22 1998-12-22 Liebel-Florsheim Company Electrocardiograph control of fluid injection
US6030344A (en) * 1996-12-04 2000-02-29 Acuson Corporation Methods and apparatus for ultrasound image quantification
US6043655A (en) * 1997-01-09 2000-03-28 Kabushiki Kaisha Toshiba MR imaging utilizing the time of flight effect
US5830143A (en) * 1997-01-21 1998-11-03 Wisconsin Alumnin Research Foundation Gated time-resolved contrast-enhanced 3D MR angiography
US5961460A (en) * 1997-04-11 1999-10-05 Acuson Corporation Ultrasound imaging enhancement methods and systems
US5882306A (en) * 1997-04-11 1999-03-16 Acuson Corporation Ultrasound imaging methods and systems
US5873825A (en) * 1997-04-11 1999-02-23 Wisconsin Alumni Research Foundation Three dimensional digital subtraction magnetic resonance angiography with limited k-space mask
US6044290A (en) * 1997-04-11 2000-03-28 Wisconsin Alumni Research Foundation Time-resolved digital subtraction magnetic resonance angiography using echo-planar imaging
US6110120A (en) 1997-04-11 2000-08-29 Acuson Corporation Gated ultrasound imaging apparatus and method
US7048716B1 (en) 1997-05-15 2006-05-23 Stanford University MR-compatible devices
US6272370B1 (en) * 1998-08-07 2001-08-07 The Regents Of University Of Minnesota MR-visible medical device for neurological interventions using nonlinear magnetic stereotaxis and a method imaging
US6050944A (en) * 1997-06-17 2000-04-18 Acuson Corporation Method and apparatus for frequency control of an ultrasound system
US6132374A (en) * 1997-08-01 2000-10-17 Acuson Corporation Ultrasonic imaging method and system
US6023977A (en) * 1997-08-01 2000-02-15 Acuson Corporation Ultrasonic imaging aberration correction system and method
US5944666A (en) * 1997-08-21 1999-08-31 Acuson Corporation Ultrasonic method for imaging blood flow including disruption or activation of contrast agent
US5873830A (en) * 1997-08-22 1999-02-23 Acuson Corporation Ultrasound imaging system and method for improving resolution and operation
US6106465A (en) * 1997-08-22 2000-08-22 Acuson Corporation Ultrasonic method and system for boundary detection of an object of interest in an ultrasound image
US5928151A (en) * 1997-08-22 1999-07-27 Acuson Corporation Ultrasonic system and method for harmonic imaging in three dimensions
US5924987A (en) * 1997-10-06 1999-07-20 Meaney; James F. M. Method and apparatus for magnetic resonance arteriography using contrast agents
US5935069A (en) * 1997-10-10 1999-08-10 Acuson Corporation Ultrasound system and method for variable transmission of ultrasonic signals
US5860931A (en) * 1997-10-10 1999-01-19 Acuson Corporation Ultrasound method and system for measuring perfusion
US20010045832A1 (en) 1997-11-26 2001-11-29 Kenneth W. Belt Peripheral vascular array
WO1999030177A1 (en) * 1997-12-08 1999-06-17 Koninklijke Philips Electronics N.V. Method of and device for imaging an object by means of magnetic resonance
US5897500A (en) * 1997-12-18 1999-04-27 Acuson Corporation Ultrasonic imaging system and method for displaying composite fundamental and harmonic images
DE19811349C1 (en) 1998-03-16 1999-10-07 Siemens Ag Process for contrast substance tracing using medical imaging appts.
US6381486B1 (en) 1999-01-08 2002-04-30 Wisconsin Alumni Research Foundation Magnetic resonance angiography with vessel segmentation
US7254437B2 (en) 1998-04-17 2007-08-07 Kabushiki Kaisha Toshiba MR imaging providing tissue/blood contrast image
US6249694B1 (en) * 1998-07-17 2001-06-19 General Electric Company Method for peripheral MR angiography
US6023162A (en) * 1998-07-23 2000-02-08 Duke University Three-dimensional morphology by magnetic resonance imaging
AU6145499A (en) * 1998-09-17 2000-04-03 Brigham And Women's Hospital Method and apparatus for projecting mr angiographic data
US6048316A (en) * 1998-10-16 2000-04-11 Acuson Corporation Medical diagnostic ultrasonic imaging system and method for displaying composite fundamental and harmonic images
US6198960B1 (en) 1998-11-24 2001-03-06 Mayo Foundation For Medical Education And Research Flip angle modulated magnetic resonance angiography
US6556856B1 (en) * 1999-01-08 2003-04-29 Wisconsin Alumni Research Foundation Dual resolution acquisition of magnetic resonance angiography data with vessel segmentation
US7047054B2 (en) * 1999-03-12 2006-05-16 Cas Medical Systems, Inc. Laser diode optical transducer assembly for non-invasive spectrophotometric blood oxygenation monitoring
US6425864B1 (en) 1999-04-15 2002-07-30 General Electric Company Method and apparatus for optimal imaging of the peripheral vasculature
US6393314B1 (en) 1999-05-06 2002-05-21 General Electric Company RF driven resistive ablation system for use in MRI guided therapy
DE19924448A1 (en) 1999-05-28 2000-12-07 Siemens Ag Three-dimensional data set extraction method for magnetic resonance imaging
US20030216643A1 (en) * 1999-07-30 2003-11-20 Zatezalo Douglas M. Programmable injector control
US6339718B1 (en) * 1999-07-30 2002-01-15 Medrad, Inc. Programmable injector control
KR100577410B1 (en) * 1999-11-30 2006-05-08 엘지.필립스 엘시디 주식회사 X-ray image sensor and a method for fabricating the same
DE60139309D1 (en) * 2000-03-30 2009-09-03 Wisconsin Alumni Res Found MAGNETIC RESONANCE ANGIOGRAPHY WITH AUTOMATIC VASCULAR SEGMENTATION
US6626862B1 (en) 2000-04-04 2003-09-30 Acist Medical Systems, Inc. Fluid management and component detection system
US6704592B1 (en) 2000-06-02 2004-03-09 Medrad, Inc. Communication systems for use with magnetic resonance imaging systems
US6450963B1 (en) * 2000-06-30 2002-09-17 Ackrad Laboratories, Inc. Apparatus and method for ultrasonic imaging of the uterus and fallopian tubes using air and saline
US6377835B1 (en) * 2000-08-30 2002-04-23 Siemens Aktiengesellschaft Method for separating arteries and veins in 3D MR angiographic images using correlation analysis
US6597936B1 (en) 2000-11-14 2003-07-22 Koninklijke Philips Electronics, N.V. Focused point oversampling for temporally and spatially resolving dynamic studies
US6639211B1 (en) * 2000-11-22 2003-10-28 Koninklijke Philips Electronics, N.V. Contrast-enhanced MRA including an effective zero-latency method of bolus detection
USRE45725E1 (en) 2000-12-21 2015-10-06 University Of Virginia Patent Foundation Method and apparatus for spin-echo-train MR imaging using prescribed signal evolutions
AU2002232876A1 (en) 2000-12-21 2002-07-01 University Of Virginia Patent Foundation Method and apparatus for spin-echo-train mr imaging using prescribed signal evolutions
US6587708B2 (en) * 2000-12-29 2003-07-01 Ge Medical Systems Global Technology, Llc Method for coherent steady-state imaging of constant-velocity flowing fluids
US6503203B1 (en) * 2001-01-16 2003-01-07 Koninklijke Philips Electronics N.V. Automated ultrasound system for performing imaging studies utilizing ultrasound contrast agents
IL141137A0 (en) * 2001-01-28 2002-02-10 Caesaria Med Electronics Ltd Liquid pump
US6549798B2 (en) 2001-02-07 2003-04-15 Epix Medical, Inc. Magnetic resonance angiography data
US6577887B2 (en) 2001-03-13 2003-06-10 Floyd Wolff Apparatus and method for improving diagnoses
IL142446A (en) * 2001-04-04 2009-07-20 Caesarea Medical Electronics Ltd Flow set and a method to identify said flow set by a liquid pump
WO2003006101A2 (en) * 2001-07-10 2003-01-23 Medrad, Inc. Devices, systems and method for infusion of fluids
US6845260B2 (en) * 2001-07-18 2005-01-18 Koninklijke Philips Electronics N.V. Automatic vessel indentification for angiographic screening
TWI221406B (en) * 2001-07-30 2004-10-01 Epix Medical Inc Systems and methods for targeted magnetic resonance imaging of the vascular system
US6597938B2 (en) 2001-08-16 2003-07-22 Koninklijke Philips Electronics, N.V. System for assistance of parameter determination and diagnosis in MRI dynamic uptake studies
US20030169911A1 (en) * 2001-12-11 2003-09-11 Snyder Gregory B. Method and apparatus for processing and displaying images of the arteries and veins
US7109974B2 (en) * 2002-03-05 2006-09-19 Matsushita Electric Industrial Co., Ltd. Remote control system including an on-screen display (OSD)
WO2003086191A1 (en) * 2002-04-08 2003-10-23 Robarts Research Institute System and method for generating t1 and t2 maps
CA2418229A1 (en) * 2002-05-16 2003-11-16 Rohan Dharmakumar Microbubble construct for sensitivity enhanced mr manometry
WO2003097125A2 (en) * 2002-05-17 2003-11-27 Case Western Reserve University Double contrast technique for mri-guided vascular interventions
US7553295B2 (en) * 2002-06-17 2009-06-30 Iradimed Corporation Liquid infusion apparatus
US7267661B2 (en) * 2002-06-17 2007-09-11 Iradimed Corporation Non-magnetic medical infusion device
US7404809B2 (en) 2004-10-12 2008-07-29 Iradimed Corporation Non-magnetic medical infusion device
US20030236489A1 (en) 2002-06-21 2003-12-25 Baxter International, Inc. Method and apparatus for closed-loop flow control system
US7927275B2 (en) * 2002-08-26 2011-04-19 The Cleveland Clinic Foundation System and method of aquiring blood-vessel data
US7285287B2 (en) * 2002-11-14 2007-10-23 Synecor, Llc Carbon dioxide-assisted methods of providing biocompatible intraluminal prostheses
US20040098106A1 (en) * 2002-11-14 2004-05-20 Williams Michael S. Intraluminal prostheses and carbon dioxide-assisted methods of impregnating same with pharmacological agents
US7801583B2 (en) * 2002-12-10 2010-09-21 Neorad As Extravasation detector
US20080132797A1 (en) * 2002-12-10 2008-06-05 Knut Brabrand Monitoring infusion of a substance
US7648678B2 (en) 2002-12-20 2010-01-19 Dako Denmark A/S Method and system for pretreatment of tissue slides
US6932930B2 (en) * 2003-03-10 2005-08-23 Synecor, Llc Intraluminal prostheses having polymeric material with selectively modified crystallinity and methods of making same
US7792568B2 (en) * 2003-03-17 2010-09-07 Boston Scientific Scimed, Inc. MRI-visible medical devices
US7343193B2 (en) * 2003-06-16 2008-03-11 Wisconsin Alumni Research Foundation Background suppression method for time-resolved magnetic resonance angiography
AR047692A1 (en) * 2003-07-10 2006-02-08 Epix Medical Inc IMAGES OF STATIONARY WHITE
US7632245B1 (en) * 2003-08-18 2009-12-15 Medrad, Inc. Devices, systems and methods for delivery of a fluid into a patient during a magnetic resonance procedure
US20050043613A1 (en) * 2003-08-20 2005-02-24 Eduardo Figueiredo System and method to reduce artifacts and improve coverage in mr spectroscopy
US7467006B2 (en) * 2003-10-07 2008-12-16 Hitachi Medical Corporation Magnetic resonance imaging system and contrast-enhanced angiography
EP1678987A1 (en) * 2003-10-16 2006-07-12 Philips Intellectual Property & Standards GmbH Device and method for providing an angiographic image
US7606610B2 (en) * 2003-11-05 2009-10-20 Allegheny-Singer Research Institute Rapid three-dimensional magnetic resonance angiography
US7734331B2 (en) * 2004-03-02 2010-06-08 General Electric Company Systems, methods and apparatus for preparation, delivery and monitoring of radioisotopes in positron emission tomography
EP1812101A4 (en) 2004-11-16 2014-04-23 Medrad Inc Modeling of pharmaceutical propagation
HUE034171T2 (en) 2004-11-24 2018-02-28 Bayer Healthcare Llc Devices, systems and methods for fluid delivery
DE102005005687A1 (en) 2005-02-08 2006-08-17 Siemens Ag Magnetic resonance equipment for treating intra luminal pathologies of gastro intestinal tract, has image recording unit recording raw data containing perfusion information and/or angiographic information of identified abnormality
US7708163B2 (en) * 2005-02-24 2010-05-04 Trivascular2, Inc. Constant force material delivery system and method
US7945305B2 (en) * 2005-04-14 2011-05-17 The Board Of Trustees Of The University Of Illinois Adaptive acquisition and reconstruction of dynamic MR images
JP5113060B2 (en) 2005-09-22 2013-01-09 ウイスコンシン アラムナイ リサーチ ファウンデーシヨン Reconstruction of beating heart image
US20100268065A1 (en) * 2006-01-25 2010-10-21 John Pile-Spellman Systems and methods for imaging a blood vessel using temperature sensitive magnetic resonance imaging
US8676293B2 (en) * 2006-04-13 2014-03-18 Aecc Enterprises Ltd. Devices, systems and methods for measuring and evaluating the motion and function of joint structures and associated muscles, determining suitability for orthopedic intervention, and evaluating efficacy of orthopedic intervention
US8200311B2 (en) * 2006-04-21 2012-06-12 Cornell Research Foundation, Inc. Cardiac motion artifact suppression using ECG ordering
JP4268976B2 (en) * 2006-06-15 2009-05-27 ジーイー・メディカル・システムズ・グローバル・テクノロジー・カンパニー・エルエルシー Imaging device
US20080051648A1 (en) * 2006-08-25 2008-02-28 Suri Jasjit S Medical image enhancement system
WO2008029407A2 (en) * 2006-09-06 2008-03-13 Yeda Research And Development Co. Ltd. Apparatus and method for monitoring drug delivery
US7974682B2 (en) * 2006-11-22 2011-07-05 Marcela Gonzalez Molezzi System and method to adaptively control contrast-enhanced diagnostic imaging procedure
US20100030073A1 (en) * 2006-12-29 2010-02-04 Medrad, Inc. Modeling of pharmaceutical propagation
DK2097835T3 (en) 2006-12-29 2018-09-03 Bayer Healthcare Llc PATIENT-BASED PARAMETER GENERATION SYSTEMS FOR MEDICAL INJECTION PROCEDURES
DE102007006142A1 (en) * 2007-02-07 2008-08-14 Siemens Ag Method and apparatus for automatically determining a flow of body fluid within vessels of a living being
US8219176B2 (en) * 2007-03-08 2012-07-10 Allegheny-Singer Research Institute Single coil parallel imaging
US7541808B2 (en) * 2007-04-11 2009-06-02 Allegheny-Singer Research Institute Rapid MRI dynamic imaging using MACH
JP2008259738A (en) * 2007-04-13 2008-10-30 Ge Medical Systems Global Technology Co Llc Ultrasonic diagnostic equipment and ultrasonic diagnostic equipment system
US20100201361A1 (en) * 2007-05-03 2010-08-12 Edelman Robert R System and method for passive catheter tracking with magnetic resonance imaging
EP2152337B1 (en) * 2007-05-04 2013-04-17 Mallinckrodt LLC Methods for controlling medical fluid injections
DE102007025399A1 (en) * 2007-05-31 2008-12-11 Siemens Ag Medical technical diagnostic system
US8105282B2 (en) 2007-07-13 2012-01-31 Iradimed Corporation System and method for communication with an infusion device
CN103976736B (en) 2007-07-17 2017-01-11 拜耳医药保健有限责任公司 Devices and systems for determination of parameters for a procedure, for estimation of cardiopulmonary function and for fluid delivery
US20090099481A1 (en) 2007-10-10 2009-04-16 Adam Deitz Devices, Systems and Methods for Measuring and Evaluating the Motion and Function of Joints and Associated Muscles
US8608484B2 (en) * 2008-03-04 2013-12-17 Medrad, Inc. Dynamic anthropomorphic cardiovascular phantom
CN101977549A (en) * 2008-03-18 2011-02-16 皇家飞利浦电子股份有限公司 Dynamic planning tool for use in contrast-enhanced dynamic scan in magnetic resonance imaging
US20100004526A1 (en) * 2008-06-04 2010-01-07 Eigen, Inc. Abnormality finding in projection images
US8315449B2 (en) * 2008-06-24 2012-11-20 Medrad, Inc. Identification of regions of interest and extraction of time value curves in imaging procedures
US8688193B2 (en) * 2008-06-26 2014-04-01 Allegheny-Singer Research Institute Magnetic resonance imager, method and program which continuously applies steady-state free precession to k-space
US8170307B2 (en) 2008-09-23 2012-05-01 The Methodist Hospital Automated wall motion quantification in aortic dissections
US8131046B2 (en) * 2008-10-29 2012-03-06 Allegheny-Singer Research Institute Magnetic resonance imager using cylindrical offset region of excitation, and method
US9421330B2 (en) 2008-11-03 2016-08-23 Bayer Healthcare Llc Mitigation of contrast-induced nephropathy
US8198892B2 (en) * 2009-04-22 2012-06-12 Allegheny-Singer Research Institute Steady-state-free-precession (SSFP) magnetic resonance imaging (MRI) and method
WO2011038236A2 (en) 2009-09-25 2011-03-31 Ortho Kinematics, Inc. Systems and devices for an integrated imaging system with real-time feedback loops and methods therefor
US8405394B2 (en) * 2009-10-20 2013-03-26 Allegheny-Singer Research Institute Targeted acquisition using holistic ordering (TACHO) approach for high signal to noise imaging
US20110215805A1 (en) * 2010-03-03 2011-09-08 Allegheny-Singer Research Institute MRI and method using multi-slice imaging
US8441257B2 (en) 2010-04-27 2013-05-14 Northshore University Healthsystem Time resolved spin labeled MRI cineangiography
RU2016138172A (en) 2010-06-24 2018-12-12 Байер Медикэл Кер Инк. MODELING THE DISTRIBUTION OF A PHARMACEUTICAL PRODUCT AND GENERATION OF PARAMETERS FOR INJECTION PROTOCOLS
RU2603823C2 (en) 2011-03-18 2016-11-27 Либэль-Фларшайм Кампани ЭлЭлСи Apparatus and method to determine contrast media injection parameters to control signal intensity during magnetic resonance angiography
US9700229B2 (en) 2011-04-01 2017-07-11 Mayo Foundation For Medical Education And Research System and method for imbedded, high-spatial resolution, fluoroscopic tracking of multi-station, contrast-enhanced magnetic resonance angiography
US8854041B2 (en) * 2011-05-20 2014-10-07 Kabushiki Kaisha Toshiba Spatially shaped pre-saturation profile for enhanced non-contrast MRA
CN106975117A (en) 2011-09-21 2017-07-25 拜耳医药保健有限责任公司 Continuous multiple fluid pump device, driving and actuating system and method
RU2605272C2 (en) 2012-05-14 2016-12-20 БАЙЕР ХелсКер ЛЛСи Systems and methods of determining protocols of injection of pharmaceutical fluid on the basis of voltage on x-ray tube
US9101713B2 (en) 2013-03-12 2015-08-11 Bayer Medical Care Inc. Constant force syringe
US9555379B2 (en) 2013-03-13 2017-01-31 Bayer Healthcare Llc Fluid path set with turbulent mixing chamber, backflow compensator
US9486573B2 (en) 2013-03-14 2016-11-08 Bayer Healthcare Llc Fluid delivery system and method of fluid delivery to a patient
BR112016000769A2 (en) 2013-07-17 2018-03-20 Bayer Medical Care Inc cartridge-based hole infuser
JP6552798B2 (en) * 2013-11-29 2019-07-31 キヤノンメディカルシステムズ株式会社 Medical image processing apparatus, X-ray diagnostic apparatus, and medical image processing program
EP3084462B1 (en) 2013-12-20 2019-05-01 Koninklijke Philips N.V. Breath-hold detection for magnetic resonance imaging
EP3125766A4 (en) * 2014-04-04 2018-01-24 Bayer Healthcare, LLC Combined radiopharmaceutical imaging system
US20170089997A1 (en) * 2014-05-19 2017-03-30 Boston Medical Center Corporation Aqueous contrast agents for dynamic mri and mra
US10379189B2 (en) * 2014-07-28 2019-08-13 Case Western Reserve University Simultaneous magnetic resonance angiography and perfusion with nuclear magnetic resonance fingerprinting
JP6749918B2 (en) 2015-01-09 2020-09-02 バイエル・ヘルスケア・エルエルシーＢａｙｅｒ ＨｅａｌｔｈＣａｒｅ ＬＬＣ Multi-fluid delivery system with multi-use disposable set and features thereof
US20160354161A1 (en) 2015-06-05 2016-12-08 Ortho Kinematics, Inc. Methods for data processing for intra-operative navigation systems
EP3423130A1 (en) 2016-03-03 2019-01-09 Bayer Healthcare LLC System and method for improved fluid delivery in multi-fluid injector systems
EP3513212A1 (en) 2016-11-22 2019-07-24 Bayer Healthcare LLC Synthetic magnetic resonance imaging and magnetic resonance fingerprinting with a contrast agent, and determination of a contrast agent injection protocol
JP7221885B2 (en) 2017-08-31 2023-02-14 バイエル・ヘルスケア・エルエルシー Injector pressure calibration system and method
CA3068739A1 (en) 2017-08-31 2019-03-07 Bayer Healthcare Llc Fluid path impedance assessment for improving fluid delivery performance
US11779702B2 (en) 2017-08-31 2023-10-10 Bayer Healthcare Llc Method for dynamic pressure control in a fluid injector system
US11478581B2 (en) 2017-08-31 2022-10-25 Bayer Healthcare Llc Fluid injector system volume compensation system and method
WO2019046261A1 (en) 2017-08-31 2019-03-07 Bayer Healthcare Llc System and method for drive member position and fluid injector system mechanical calibration
US11268506B2 (en) 2017-12-22 2022-03-08 Iradimed Corporation Fluid pumps for use in MRI environment
US11642172B2 (en) * 2019-03-05 2023-05-09 Biosense Webster (Israel) Ltd. Showing catheter in brain
CN113506309B (en) * 2021-09-10 2021-12-03 南通华恩医疗设备制造有限公司 Medical data variable measurement monitoring method and system based on artificial intelligence

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3973554A (en) * 1975-04-24 1976-08-10 The United States Of America As Represented By The Secretary Of The Department Of Health, Education And Welfare Radiation safety shield for a syringe
US4006736A (en) * 1974-11-27 1977-02-08 Medrad, Inc. Angiographic injector

Family Cites Families (54)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4202333A (en) * 1978-11-08 1980-05-13 Minnesota Mining And Manufacturing Company Fluid dispensing device
US4430079A (en) * 1978-11-08 1984-02-07 Minnesota Mining And Manufacturing Company Fluid dispensing device
US4298000A (en) * 1978-11-08 1981-11-03 Minnesota Mining And Manufacturing Company Fluid dispensing device
US4585008A (en) * 1982-09-29 1986-04-29 Technicare Corporation Real time cardiac radionuclide imaging
US4585941A (en) * 1983-02-28 1986-04-29 E. R. Squibb & Sons, Inc. Dosimetry system for strontium-rubidium infusion pump
US5087439A (en) * 1984-11-13 1992-02-11 Salutar, Inc. Paramagnetic metal-diethylenetriamine-pentaacetic acid partial amide complexes for magnetic resonance imaging
US4826673A (en) * 1985-01-09 1989-05-02 Mallinckrodt, Inc. Methods and compositions for enhancing magnetic resonance imaging
US4880008A (en) * 1985-05-08 1989-11-14 The General Hospital Corporation Vivo enhancement of NMR relaxivity
US4777957A (en) * 1985-06-14 1988-10-18 General Electric Company Method for measuring and imaging fluid flow
US5010191A (en) * 1985-08-19 1991-04-23 The Regents Of The University Of California Imaging agents for in vivo magnetic resonance and scintigraphic imaging
IL76397A0 (en) * 1985-09-13 1986-01-31 Elscint Ltd System for decision making and implementation in imaging systems
US4770183A (en) * 1986-07-03 1988-09-13 Advanced Magnetics Incorporated Biologically degradable superparamagnetic particles for use as nuclear magnetic resonance imaging agents
US5055288A (en) * 1987-06-26 1991-10-08 Advanced Magnetics, Inc. Vascular magnetic imaging method and agent comprising biodegradeable superparamagnetic metal oxides
US4718424A (en) * 1986-08-07 1988-01-12 Stanford University NMR imaging of blood flow by moment variation of magnetic gradients
US4877599A (en) * 1986-11-10 1989-10-31 New England Deaconess Hospital Corporation Detection of vascular disease with labelled antibodies
US4822594A (en) * 1987-01-27 1989-04-18 Gibby Wendell A Contrast enhancing agents for magnetic resonance images
JPS63230157A (en) * 1987-03-20 1988-09-26 株式会社日立製作所 Blood flow imaging method
US5011686A (en) * 1987-09-21 1991-04-30 Creative Biomolecules, Inc. Thrombus specific conjugates
US5260050A (en) * 1988-09-29 1993-11-09 Ranney David F Methods and compositions for magnetic resonance imaging comprising superparamagnetic ferromagnetically coupled chromium complexes
US5078986A (en) * 1989-02-15 1992-01-07 Mallinckrodt Medical, Inc. Method for enhancing magnetic resonance imaging using an image altering agent containing an excess of chelating agent
US5034694A (en) * 1989-11-22 1991-07-23 Picker International, Inc. Minimum basis set MR angiography
JPH03173532A (en) 1989-12-04 1991-07-26 Toshiba Corp Magnetic resonance imaging device
US5190744A (en) * 1990-03-09 1993-03-02 Salutar Methods for detecting blood perfusion variations by magnetic resonance imaging
US5494655A (en) 1990-03-09 1996-02-27 The Regents Of The University Of California Methods for detecting blood perfusion variations by magnetic resonance imaging
US5287273A (en) * 1990-03-15 1994-02-15 Mount Sinai School Of Medicine Functional organ images
US5315997A (en) * 1990-06-19 1994-05-31 Molecular Biosystems, Inc. Method of magnetic resonance imaging using diamagnetic contrast
FR2664153B1 (en) 1990-07-06 1992-09-11 Gen Electric Cgr RADIODIAGNOSTIC SYSTEM FOR ANGIOGRAPHIC EXAMINATION WITH AUTOMATIC EMBLEM TRACKING DEVICE.
US5167232A (en) * 1990-08-07 1992-12-01 Ihc Hospitals, Inc. Magnetic resonance angiography by sequential multiple thin slab three dimensional acquisition
US5141740A (en) * 1990-11-21 1992-08-25 Mallinckrodt Medical, Inc. Complexes and compositions for magnetic resonance imaging and usage methods
US5300031A (en) * 1991-06-07 1994-04-05 Liebel-Flarsheim Company Apparatus for injecting fluid into animals and disposable front loadable syringe therefor
US5243284A (en) 1991-07-24 1993-09-07 Board Of Trustees Of The Leland Stanford Junior University Method of magnetic resonance reconstruction imaging from projections using partial data collected in k-space
US5522390A (en) * 1991-11-21 1996-06-04 U.S. Philips Corporation Magnetic resonance imaging method
DE4218321A1 (en) 1991-12-09 1993-06-17 Siemens Ag DIAGNOSTIC SYSTEM
JP3403751B2 (en) 1992-03-31 2003-05-06 株式会社東芝 Magnetic resonance imaging
US5305751A (en) * 1992-06-04 1994-04-26 Biomagnetic Technologies, Inc. Measurement of liquid flows in a living organism
JP2637336B2 (en) 1992-06-30 1997-08-06 株式会社島津製作所 Magnetic resonance tomography equipment
US5236417A (en) * 1992-09-22 1993-08-17 Utah Pioneer Medical, Inc. Cholangiography catheter apparatus and method
IT1271136B (en) * 1993-03-23 1997-05-27 Ausimont Spa PROCESS OF (CO) POLYMERIZATION IN AQUEOUS EMULSION OF FLUORINATED OLEFINIC MONOMERS
US5472403A (en) * 1993-05-11 1995-12-05 The Regents Of The University Of California Device for automatic injection of radionuclide
US5417213A (en) * 1993-06-07 1995-05-23 Prince; Martin R. Magnetic resonance arteriography with dynamic intravenous contrast agents
US5579767A (en) 1993-06-07 1996-12-03 Prince; Martin R. Method for imaging abdominal aorta and aortic aneurysms
US5590654A (en) * 1993-06-07 1997-01-07 Prince; Martin R. Method and apparatus for magnetic resonance imaging of arteries using a magnetic resonance contrast agent
US5515851A (en) * 1993-07-30 1996-05-14 Goldstein; James A. Angiographic fluid control system
US5684398A (en) 1993-09-02 1997-11-04 Hitachi Medical Corporation Fluid measurement method using nuclear magnetic resonance imaging and apparatus therefor
US5423315A (en) 1993-11-22 1995-06-13 Picker International, Inc. Magnetic resonance imaging system with thin cylindrical uniform field volume and moving subjects
US5494036A (en) 1993-11-26 1996-02-27 Medrad, Inc. Patient infusion system for use with MRI
US5515863A (en) * 1994-01-07 1996-05-14 Fonar Corporation Gastrointestinal magnetic resonance imaging
US5636259A (en) 1995-05-18 1997-06-03 Continental X-Ray Corporation Universal radiographic/fluoroscopic digital room
US5833607A (en) 1996-03-25 1998-11-10 Siemens Corporate Research, Inc. Automatic full-leg mosaic and display for peripheral angiography
US5692508A (en) 1996-04-15 1997-12-02 Siemens Medical Systems, Inc. Cardiac-gated 3-dimensional MR angiography
US5808468A (en) 1996-12-13 1998-09-15 Bis; Kostaki G. Universal kinematic imaging table for rapid positional changes in patient centering
US5873825A (en) 1997-04-11 1999-02-23 Wisconsin Alumni Research Foundation Three dimensional digital subtraction magnetic resonance angiography with limited k-space mask
US5928148A (en) 1997-06-02 1999-07-27 Cornell Research Foundation, Inc. Method for performing magnetic resonance angiography over a large field of view using table stepping
US5924987A (en) * 1997-10-06 1999-07-20 Meaney; James F. M. Method and apparatus for magnetic resonance arteriography using contrast agents

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4006736A (en) * 1974-11-27 1977-02-08 Medrad, Inc. Angiographic injector
US3973554A (en) * 1975-04-24 1976-08-10 The United States Of America As Represented By The Secretary Of The Department Of Health, Education And Welfare Radiation safety shield for a syringe

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Radiology, Volume 180, Number 3, September 1991, pp. 637-640, (SCOTT A. MIROWITZ, MD et al.), "Normal Abdominal Enhancement Patterns with Dynamic Gadolinium-enhanced MR Imaging". *

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