WO1984004666A1 - Contraceptive for animals - Google Patents

Contraceptive for animals Download PDF

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Publication number
WO1984004666A1
WO1984004666A1 PCT/FR1984/000137 FR8400137W WO8404666A1 WO 1984004666 A1 WO1984004666 A1 WO 1984004666A1 FR 8400137 W FR8400137 W FR 8400137W WO 8404666 A1 WO8404666 A1 WO 8404666A1
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WO
WIPO (PCT)
Prior art keywords
contraceptive
female
vagina
product
spermicidal
Prior art date
Application number
PCT/FR1984/000137
Other languages
French (fr)
Inventor
Jean Robert Fournier
Original Assignee
Europ Rech Instr
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Europ Rech Instr filed Critical Europ Rech Instr
Publication of WO1984004666A1 publication Critical patent/WO1984004666A1/en

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0034Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A61K9/0036Devices retained in the vagina or cervix for a prolonged period, e.g. intravaginal rings, medicated tampons, medicated diaphragms
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K21/00Devices for assisting or preventing mating
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61DVETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
    • A61D1/00Surgical instruments for veterinary use
    • A61D1/06Castrating appliances
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F6/00Contraceptive devices; Pessaries; Applicators therefor
    • A61F6/06Contraceptive devices; Pessaries; Applicators therefor for use by females
    • A61F6/08Pessaries, i.e. devices worn in the vagina to support the uterus, remedy a malposition or prevent conception, e.g. combined with devices protecting against contagion

Definitions

  • US-A-4,271,835 describes (column 2, lines 9 to 14) that we already know about intravaginal absorbent products and impregnated with a spermicidal solution acting as contraceptives for three reasons: barrier effect, absorption and retention of sperm and prolonged spermicidal action.
  • the present invention relates to a contraceptive which first has an effect intended to move the body away from the animal species considered to prevent coitus and then a possible barrier and spermicide effect in the event of failure of the deterrent effect.
  • the invention moreover, allows the use of an endovaginal contraceptive which can be put in and removed by the owner of the animal in a very simple manner and without having to call upon a veterinarian.
  • the invention relates to a contraceptive for female animals, to be placed in the vagina of a female in the immediate vicinity of the cervix, characterized in that it comprises a hydrophilic support intended to be dilated by absorption of physiological liquids and which contains on the one hand a product with slow diffusion likely to cause a repulsive reaction in males of the animal species considered and, on the other hand, a slowly soluble spermicidal product.
  • the hydrophilic support is held pinched by a ring near its end opposite to that which must be located near the cervix of the female; - the ring secures the hydrophilic support and a capsule controlling at least one product dispersible in the vagina of the female;
  • FIG. 1 is a schematic view showing in external view a contraceptive according to a particular embodiment of the invention.
  • Figure 2 is a schematic view showing a contraceptive of the type of that of Figure 1 placed in the vagina of a bitch seen in vertical section.
  • Figure 3 is a view of the same contraceptive placed in the vagina of a bitch seen in horizontal section.
  • a contraceptive comprising a hydrophilic support 1 for a capsule 2 containing at least one slowly soluble product.
  • the capsule 2 is pierced with small holes 3 through which the product disperses.
  • the hydrophilic support 1 can be of any known type and, in particular, composed of one or more fibrous layers intended to expand by absorption of physiological liquids.
  • This contraceptive occupies a small volume before use and can therefore be put in place easily, without any pain for the animal, in particular with an applicator. It then expands by absorption of physiological fluids, in particular retaining the odorous secretions characteristic of the availability of the female and her fertility.
  • the support 1 and the capsule 2 can be joined by means of a sort of inextensible ring 4 so that the expansion of the support 1 occurs towards its free end but not towards its end enclosed by the ring 4. All of the contraceptive which has just been described also includes a wire 5 which is fixed, here, to the capsule 2 but which could also be secured to the support 1 or to the ring 4.
  • This contraceptive is intended to be inserted into the vagina A of an animal female as close as possible to the cervix B of the uterus C.
  • These products can be a spermicide and a repellent intended for males of the animal species considered.
  • the presence of the dilated support 1 is favorable to the arrest of the spermatozoa and to their maintenance in an area of great spermicidal activity.
  • This contraceptive therefore acts in three ways: by preventive chemical effect due to the presence of the repellant capable of preventing coitus, by protective chemical effect due to the presence of the spermicidal product and by mechanical or “barrier effect” effect due to the presence of hydrophilic support 1.
  • the spermicidal product is placed in the support 1 itself, in particular by dispersion during the manufacture of the contraceptive.
  • the contraceptive product continues to permeate the vagina but is particularly concentrated in the support 1, where one expects a barrier effect of sperm and this, of course, strengthens the action of the contraceptive.
  • the capsule 2 is located closest to the vulva D and if the repellant is placed in this capsule 2, it promotes its dispersion towards the vulva D where it will be particularly well perceived by the males of the animal species considered.
  • the wire 5 is preferably made of an elastic but relatively rigid material, that is to say “with memory” so that it cannot be folded back inside the vagina especially during coitus .
  • This wire 5 is advantageously made of a very smooth synthetic material avoiding friction as much as possible, so that it is insensitive to the movements of the penis and exerts no traction on the contraceptive suitably held in place.
  • the diameter of the wire 5 as well as its flexibility should be chosen so as not to be in any way injurious, either for the female or for the mane.
  • the length of the wire 5 is chosen so that it can extend beyond the vulva D, so that by pulling on this free end one can extract the contraceptive.
  • the fertile period of the female occurs twice a year and is preceded for about nine days by bleeding which very often causes blemishes and which therefore constitute a very serious inconvenience for owners. bitches.
  • a contraceptive in accordance with the invention a bleeding absorption effect is obtained which avoids external stains.
  • the contraceptive according to the invention is used as an absorbent pad and can be changed as often as necessary.
  • the contraceptive according to the invention comprising, in addition to the spermicidal product, an internal repellant product having external emanations which cannot be neutralized neither by the flows, nor by the bites of the dog, has a particularly great preventive effectiveness.
  • the contraceptive according to the invention takes on its full value since the spermicidal product is held in place by the support 1 perfectly dilated thanks to the absorption of these physiological liquids.
  • the contraceptive exerts its double chemical and mechanical action before the sperm can reach the cervix B.
  • the contraceptive which has just been described can be produced according to various variants making it possible to adapt it as well as possible to different animal species (cats, mares, etc.) and can receive modifications such as pure suppression and sim pie of the ring 4 and the subjugation of the wire 5 directly to the support 1 for example.
  • dispersible products spermicide and / or repellant
  • dispersible products provided in all kinds of forms: in a capsule 2 or dispersed in the hydrophilic support 1 as described above, or else dispersed in a solid substance itself soluble.

Abstract

The contraceptive comprises on one hand a repulsive substance and on the other hand a spermicidal substance which are slowly soluble, as well as a hydrophilic carrier (1). The substances are contained for example in a capsule (2) or dispersed in the carrier (1). The contraceptive is placed in the vagina (A) of the female, at the vicinity of the cervix uteri (B) wherein substantially perfuse secretions of physiological liquid occur. The carrier (1) absorbs said liquid and expands. Thereby it bears against the vaginal walls and maintains in place the repulsive and spermicidal substances.

Description

CONTRACEPTIF POUR ANIMAUX Les solutions adoptées pour la contraception humaine ne sont pas immédiatement transposables au problème de la contraception animale. Cela résulte non seulement des différences physiologiques et anatomiques mais également du fait que la femme a un comportement tout a fait lucide et volontaire contrairement a la femelle animale qui n'a même pas conscience du problème et ne comprend donc pas les interventions humaines en la matière. La mise en place d'un stérilet intra-utérin suppose, une intervention d'un vétérinaire et celle-ci a sur l'animal des effets traumatisants et môme dangereux pour sa vie puisqu'il est nécessaire de procéder a une anesthésie totale. CONTRACEPTIVE FOR ANIMALS The solutions adopted for human contraception cannot be immediately transposed to the problem of animal contraception. This results not only from physiological and anatomical differences but also from the fact that the woman has a completely lucid and voluntary behavior unlike the animal female who is not even aware of the problem and therefore does not understand human interventions in the matter . The implementation of an intrauterine IUD requires intervention by a veterinarian and this has traumatic effects on the animal and even dangerous for his life since it is necessary to carry out a total anesthesia.
Mais, la présence d'un stérilet n'est pas une garantie absolue de stérilité, de sorte que, môme après avoir procédé a une telle opération, le propriétaire de l'animal est enclin a vouloir s'opposer au coït du maie, ce qui est interprété par la femelle comme une agression dirigée contre son comportement instinctif naturel.However, the presence of an IUD is not an absolute guarantee of sterility, so that even after carrying out such an operation, the owner of the animal is inclined to want to object to the coitus of the man, this which is interpreted by the female as an aggression directed against her natural instinctive behavior.
On a déjà cherché à remplacer les stérilets endo-utérins par des stérilets endo-vaginaux mais le problème de leur maintien en place n'a jamais été résolu de manière satisfaisante et suppose toujours l'intervention plus ou moins acceptée d'un vétérinaire. Ainsi, le brevet US-A-4.271.835 décrit (colonne 2, lignes 9 à 14) que l'on connaît déjà des produits absorbants intra-vaginaux et imprégnés d'une solution spermicide agissant comme contraceptifs a trois titres : effet barrière, absorption et rétention du sperme et action spermicide prolongée.Attempts have already been made to replace endo-uterine IUDs with endo-vaginal IUDs, but the problem of keeping them in place has never been satisfactorily resolved and always requires the intervention more or less accepted by a veterinarian. Thus, US-A-4,271,835 describes (column 2, lines 9 to 14) that we already know about intravaginal absorbent products and impregnated with a spermicidal solution acting as contraceptives for three reasons: barrier effect, absorption and retention of sperm and prolonged spermicidal action.
Toutefois, ce brevet US précise (colonne 2, lignes 44 a 55) que le tampon doit être imprégné de produit spermicide immédiatement avant son introduction dans le vagin.However, this US patent specifies (column 2, lines 44 to 55) that the tampon must be impregnated with spermicidal product immediately before its introduction into the vagina.
Les brevets US-A-4.369.773 et US-A-3.780.730 décrivent chacun un contraceptif conçu a la fois pour absorber l'éjaculat et pour contenir un produit spermicide.The patents US-A-4,369,773 and US-A-3,780,730 each describe a contraceptive designed both to absorb the ejaculate and to contain a spermicidal product.
On remarque qu'aucun des brevets décrits ci-dessus ne prévoit une action préventive du coït mais uniquement une action ultérieure. La présente invention, au contraire, concerne un contraceptif qui a d'abord un effet destiné a éloigner le maie de l'espèce animale considérée pour empêcher le coït et ensuite un effet éventuel de barrière et de spermicide en cas d'échec de l'effet dissuasif. L'invention, en outre, permet l'emploi d'un contraceptif endovaginal qui peut être mis en place et retiré par le propriétaire de l'animal de manière très simple et sans devoir faire, appel à un vétérinaire.It is noted that none of the patents described above provides for a preventive action of coitus but only a subsequent action. The present invention, on the contrary, relates to a contraceptive which first has an effect intended to move the body away from the animal species considered to prevent coitus and then a possible barrier and spermicide effect in the event of failure of the deterrent effect. The invention, moreover, allows the use of an endovaginal contraceptive which can be put in and removed by the owner of the animal in a very simple manner and without having to call upon a veterinarian.
A cette fin, l'invention a pour objet un contraceptif pour animaux femelles, devant être placé dans le vagin d'une femelle a proximité immédiate du col utérin, caractérisé en ce qu'il comprend un support hydrophile destiné a être dilaté par absorption de liquides physiologiques et qui contient d'une part un produit a diffusion lente de nature à provoquer une réaction répulsive chez les mâles de l'espèce animale considérée et, d'autre part, un produit spermicide lentement soluble. Selon d'autres caractéristiques de l'invention : - le support hydrophile est maintenu pincé par une bague près de son extrémité opposée à celle qui doit être située près du col de l'utérus de la femelle; - la bague solidarise le support hydrophile et une capsule contrenant au moins un produit dispersable dans le vagin de la femelle;To this end, the invention relates to a contraceptive for female animals, to be placed in the vagina of a female in the immediate vicinity of the cervix, characterized in that it comprises a hydrophilic support intended to be dilated by absorption of physiological liquids and which contains on the one hand a product with slow diffusion likely to cause a repulsive reaction in males of the animal species considered and, on the other hand, a slowly soluble spermicidal product. According to other characteristics of the invention: - the hydrophilic support is held pinched by a ring near its end opposite to that which must be located near the cervix of the female; - the ring secures the hydrophilic support and a capsule controlling at least one product dispersible in the vagina of the female;
- le contraceptif est solidaire d'un fil dont la longueur est suffisante pour qu'il puisse s'étendre jusqu'à l'extérieur de la vulve de la femelle et qui est réalisé en un matériau élastiquement déformable mais suffisamment rigide pour rester en place malgré des efforts exercés sur lui et tendant a le solliciter vers l'intérieur du vagin. L'invention sera mieux comprise par la description détaillée ci-après faite en référence au dessin annexé. Bien entendu, la description et le dessin ne sont donnés qu'à titre d'exemple indicatif et non limitatif. La figure 1 est une vue schématique montrant en vue extôrieure un contraceptif selon un mode de réalisation particulier de l' invention.- the contraceptive is secured to a wire whose length is sufficient for it to extend to the outside of the female's vulva and which is made of an elastically deformable material but sufficiently rigid to remain in place despite efforts exerted on him and tending to solicit him towards the inside of the vagina. The invention will be better understood from the detailed description below made with reference to the accompanying drawing. Of course, the description and the drawing are given only by way of an indicative and nonlimiting example. FIG. 1 is a schematic view showing in external view a contraceptive according to a particular embodiment of the invention.
La figure 2 est une vue schématique montrant un contraceptif du type de celui de la figure 1 mis en place dans le vagin d'une chienne vu en coupe verticale. La figure 3 est une vue de ce même contraceptif placé dans le vagin d 'une chienne vu en coupe horizontale.Figure 2 is a schematic view showing a contraceptive of the type of that of Figure 1 placed in the vagina of a bitch seen in vertical section. Figure 3 is a view of the same contraceptive placed in the vagina of a bitch seen in horizontal section.
En se reportant au dessin, on voit un contraceptif comprenant un support hydrophile 1 pour une capsule 2 contenant au moins un produit lentement soluble. Sur le dessin, la capsule 2 est percée de petits trous 3 par lesquels le produit se disperse.Referring to the drawing, we see a contraceptive comprising a hydrophilic support 1 for a capsule 2 containing at least one slowly soluble product. In the drawing, the capsule 2 is pierced with small holes 3 through which the product disperses.
Le support hydrophile 1 peut être de tous types connus et, notamment, composé d'une ou plusieurs nappes fibreuses destinées à se dilater par absorption de liquides physiologiques. Ce contraceptif occupe un faible volume avant emploi et peut donc être mis en place aisément, sans aucune douleur pour l'animal, notamment avec un applicateur. Il se dilate ensuite par absorption de liquides physiologiques en retenant notamment les sécrétions odorantes caractéristiques de la disponibilité de la femelle et de sa fécondité. Le support 1 et la capsule 2 peuvent être réunis au moyen d'une sorte de bague 4 inextensible afin que la dilatation du support 1 se produise vers son extrémité libre mais non vers son extrémité enserrée par la bague 4. L'ensemble du contraceptif qui vient d'être décrit comprend également un fil 5 qui est fixé, ici, à la capsule 2 mais qui pourrait aussi être assujetti au support 1 ou à la bague 4.The hydrophilic support 1 can be of any known type and, in particular, composed of one or more fibrous layers intended to expand by absorption of physiological liquids. This contraceptive occupies a small volume before use and can therefore be put in place easily, without any pain for the animal, in particular with an applicator. It then expands by absorption of physiological fluids, in particular retaining the odorous secretions characteristic of the availability of the female and her fertility. The support 1 and the capsule 2 can be joined by means of a sort of inextensible ring 4 so that the expansion of the support 1 occurs towards its free end but not towards its end enclosed by the ring 4. All of the contraceptive which has just been described also includes a wire 5 which is fixed, here, to the capsule 2 but which could also be secured to the support 1 or to the ring 4.
Ce contraceptif est destiné à être engagé dans le vagin A d'une femelle animale le plus près possible du col B de l'utérus C.This contraceptive is intended to be inserted into the vagina A of an animal female as close as possible to the cervix B of the uterus C.
A cet endroit, en effet, se trouvent de nombreuses sécrétions liquides grâce auxquelles le matériau hydrophile qui constitue le support 1 se dilate et prend appui sur les parois du vagin A et cet effet a pour résultat de maintenir en place la capsule 2 contenant le ou les produits dispersables.In this place, in fact, there are many liquid secretions thanks to which the hydrophilic material which constitutes the support 1 expands and bears on the walls of the vagina A and this effect has the result of holding in place the capsule 2 containing the or dispersible products.
Ces produits peuvent être un spermicide et un répulsif destinés aux mâles de l'espèce animale considérée.These products can be a spermicide and a repellent intended for males of the animal species considered.
En outre, la présence du support dilaté 1 est favorable à l'arrêt des spermatozoïdes et à leur maintien dans une zone de grande activité spermicide.In addition, the presence of the dilated support 1 is favorable to the arrest of the spermatozoa and to their maintenance in an area of great spermicidal activity.
Ce contraceptif agit donc de trois manières : par effet chimique préventif du fait de la présence du produit répulsif propre à éviter le coit, par effet chimique protecteur du fait de la présence du produit spermicide et par effet mécanique ou "effet barrière" dû à la présence du support hydrophile 1.This contraceptive therefore acts in three ways: by preventive chemical effect due to the presence of the repellant capable of preventing coitus, by protective chemical effect due to the presence of the spermicidal product and by mechanical or "barrier effect" effect due to the presence of hydrophilic support 1.
Pour éviter que le contraceptif soit expulsé par suite de mouvements de la paroi vaginale, il est bon de favoriser la dilatation du support 1 vers son extrémité la plus proche du col utérin B plutôt que vers son extrémité opposée. Cela est obtenu, ici, par la bague 4 qui empêche le support 1 de se dilater sur toute sa longueur. Comme on l'a représenté schématiquement en traits pointillés sur la figure 1, la dilatation a tendance à se produire en forme de cône allongé propice a maintien en place du contraceptif par un effet voisin de celui que l'on obtient avec une cheville dilatable pour le maintien d'une vis.To prevent the contraceptive from being expelled as a result of movements of the vaginal wall, it is good to encourage the dilation of the support 1 towards its end closest to the cervix B rather than towards its opposite end. This is obtained, here, by the ring 4 which prevents the support 1 from expanding over its entire length. As shown schematically in dotted lines in Figure 1, the dilation tends to occur in the form of an elongated cone conducive to keeping the contraceptive in place by an effect similar to that that is obtained with an expandable dowel for holding a screw.
Selon un mode de réalisation particulier de l'invention, le produit spermicide est disposé dans le support 1 lui-même, notamment par dispersion lors de la fabrication du contraceptif.According to a particular embodiment of the invention, the spermicidal product is placed in the support 1 itself, in particular by dispersion during the manufacture of the contraceptive.
De la sorte, le produit contraceptif continue d'imprégner le vagin mais se trouve particulièrement concentré dans le support 1, là où l'on escompte un effet barrière des spermatozoîdes et cela, bien entendu, renforce l'action du contraceptif. La capsule 2 se trouve la plus proche de la vulve D et si l'on place le produit répulsif dans cette capsule 2, on favorise sa dispersion vers la vulve D où il sera particulièrement bien perçu par les maies de l'espèce animale considérée.In this way, the contraceptive product continues to permeate the vagina but is particularly concentrated in the support 1, where one expects a barrier effect of sperm and this, of course, strengthens the action of the contraceptive. The capsule 2 is located closest to the vulva D and if the repellant is placed in this capsule 2, it promotes its dispersion towards the vulva D where it will be particularly well perceived by the males of the animal species considered.
Selon l'invention, le fil 5 est de préférence réalisé en un matériau élastique mais relativement rigide c'est-à-dire "à mémoire" afin qu'il ne puisse pas être replié à l'intérieur du vagin notamment au moment du coït.According to the invention, the wire 5 is preferably made of an elastic but relatively rigid material, that is to say "with memory" so that it cannot be folded back inside the vagina especially during coitus .
Ce fil 5 est avantageusement réalisé en une matière synthétique très lisse évitant au maximum les frottements, de sorte qu'il est insensible aux mouvenemts du pénis et n'exerce aucune traction sur le contraceptif convenablement maintenu en place.This wire 5 is advantageously made of a very smooth synthetic material avoiding friction as much as possible, so that it is insensitive to the movements of the penis and exerts no traction on the contraceptive suitably held in place.
Naturellement, le diamètre du fil 5 ainsi que sa s.ouplesse doivent être choisis pour n'être en aucun cas blessants, ni pour la femelle, ni pour le maie. La longueur du fil 5 est choisie de telle sorte qu'il puisse s'étendre au-delà de la vulve D, afin que par traction sur cette extrémité libre on puisse extraire le contraceptif.Naturally, the diameter of the wire 5 as well as its flexibility should be chosen so as not to be in any way injurious, either for the female or for the mane. The length of the wire 5 is chosen so that it can extend beyond the vulva D, so that by pulling on this free end one can extract the contraceptive.
Il faut souligner que le contraceptif qui vient d'être décrit présente des avantages supplémentaires pour certaines espèces animales telles que les chiennes.It should be emphasized that the contraceptive which has just been described has additional advantages for certain animal species such as bitches.
En effet, dans l'espèce canine, la période féconde de la femelle se produit deux fois par an et est précédée pendant environ neuf jours de saignements qui occasionnent très souvent des souilllures et qui constituent, par conséquent, un très grave inconvénient pour les propriétaires de chiennes. En mettant en place, à ce moment là, un contraceptif conforme à l'invention, on obtient un effet d'absorption des saignements qui évite les souillures extérieures.Indeed, in the canine species, the fertile period of the female occurs twice a year and is preceded for about nine days by bleeding which very often causes blemishes and which therefore constitute a very serious inconvenience for owners. bitches. By putting in place, at this time, a contraceptive in accordance with the invention, a bleeding absorption effect is obtained which avoids external stains.
Dans ce cas, le contraceptif conforme à l'invention est utilisé comme un tampon absorbant et peut être changé aussi souvent que nécessaire.In this case, the contraceptive according to the invention is used as an absorbent pad and can be changed as often as necessary.
Ces saignements occasionnent chez la chienne le besoin de se lécher et cette opération instinctive a pour inconvénient de rendre tout à fait inefficaces les produits répulsifs externes que l'on a utilisés jusqu'à ce jour pour décourager les mâles de procéder au coït et, par là, pour obtenir un effet d'infécondité.These bleeds cause the dog to lick and this instinctive operation has the disadvantage of rendering completely ineffective external repellents that have been used to date to discourage males from coitus and, by there, to get an infertility effect.
Le contraceptif conforme à l'invention comprenant, outre le produit spermicide, un produit répulsif interne ayant des émanations externes qui ne peuvent être neutralisées ni par les écoulements, ni par les lèchements de la chienne, a une efficacité préventive particulièrement grande.The contraceptive according to the invention comprising, in addition to the spermicidal product, an internal repellant product having external emanations which cannot be neutralized neither by the flows, nor by the bites of the dog, has a particularly great preventive effectiveness.
Après la première période stérile de neuf jours, se produit chez la chienne pendant environ onze jours des écoulements de liquides physiologiques moins abondants que les saignements et qui sont révélateurs de la période féconde de la chienne. A ce moment, le contraceptif conforme à l'invention prend toute sa valeur puisque le produit spermicide est maintenu en place par le support 1 parfaitement dilaté grâce â l'absorption de ces liquides physiologiques.After the first sterile period of nine days, there occurs in the dog for about eleven days flows of physiological fluids less abundant than bleeding and which are indicative of the fertile period of the dog. At this time, the contraceptive according to the invention takes on its full value since the spermicidal product is held in place by the support 1 perfectly dilated thanks to the absorption of these physiological liquids.
Ceux-ci ne produisant aucun écoulement externe, les maies sont peu ou pas sollicités par leur instinct et peuvent même, comme dit plus haut, être découragés par les émanations de produits répulsifs.These producing no external flow, the males are little or not solicited by their instinct and can even, as said above, be discouraged by the emanations of repellents.
En tout état de cause, si le coït se produit malgré tout, le contraceptif exerce sa double action chimique et mécanique avant que les spermatozoïdes aient pu atteindre le col utérin B.In any event, if coitus still occurs, the contraceptive exerts its double chemical and mechanical action before the sperm can reach the cervix B.
Le contraceptif qui vient d'être décrit peut être réalisé selon des variantes diverses permettant de l'adapter au mieux â différentes espèces animales (chattes, juments, etc.) et peut recevoir des modifications telles que la suppression pure et sim pie de la bague 4 et l'assujettissement du fil 5 directement au support 1 par exemple.The contraceptive which has just been described can be produced according to various variants making it possible to adapt it as well as possible to different animal species (cats, mares, etc.) and can receive modifications such as pure suppression and sim pie of the ring 4 and the subjugation of the wire 5 directly to the support 1 for example.
Il en est de même pour les produits dispersables (spermicide et/ou répulsif) prévus sous toutes sortes de formes : dans une capsule 2 ou dispersés dans le support hydrophile 1 comme on l'a décrit plus haut, ou bien dispersés dans une substance solide elle même soluble. The same is true for dispersible products (spermicide and / or repellant) provided in all kinds of forms: in a capsule 2 or dispersed in the hydrophilic support 1 as described above, or else dispersed in a solid substance itself soluble.

Claims

REVENDICATIONS
1- Contraceptif pour animaux femelles, devant être placé dans le vagin (A) d'une femelle à proximité immédiate du col utérin (B), caractérisé en ce qu'il comprend un support hydrophile (1) destiné à être dilaté par absorption de liquides physiologiques et qui contient d'une part un produit à diffusion lente de nature à provoquer une réaction répulsive chez les mâles de l'espèce animale considérée et, d'autre part, un produit spermicide lentement soluble.1- Contraceptive for female animals, to be placed in the vagina (A) of a female in the immediate vicinity of the cervix (B), characterized in that it comprises a hydrophilic support (1) intended to be dilated by absorption of physiological liquids and which contains on the one hand a product with slow diffusion likely to cause a repulsive reaction in males of the animal species considered and, on the other hand, a slowly soluble spermicidal product.
2- Contraceptif selon la revendication 1, caractérisé en ce que le support hydrophile (1) est maintenu pincé par une bague2- Contraceptive according to claim 1, characterized in that the hydrophilic support (1) is held pinched by a ring
(4) près de son extrémité opposée à celle qui doit être située près du col (B) de l'utérus (C) de la femelle.(4) near its end opposite to that which must be located near the cervix (B) of the uterus (C) of the female.
3- Contraceptif selon la revendication 2 caractérisé en ce que la bague (4) solidarise le support hydrophile (1) et une capsuie (2) contenant au moins un produit dispersable dans le vagin (A) de la femelle.3- Contraceptive according to claim 2 characterized in that the ring (4) secures the hydrophilic support (1) and a capsuie (2) containing at least one product dispersible in the vagina (A) of the female.
4- Contraceptif selon la revendication 1, caractérisé en ce qu'il est solidaire d'un fil (5) dont la longueur est suffisante pour qu'il puisse s'étendre jusqu'à l'extérieur de la vulve (D) de la femelle et qui est réalisé en un matériau élastiquement déformable mais suffisamment rigide pour rester en place malgré don offorts exercés sur lui et tendant â le solliciter vers l'intérieur du vagin (A). 4- Contraceptive according to claim 1, characterized in that it is integral with a wire (5) whose length is sufficient so that it can extend to the outside of the vulva (D) of the female and which is made of an elastically deformable material but rigid enough to remain in place despite the gifts exerted on it and tending to urge it towards the inside of the vagina (A).
PCT/FR1984/000137 1983-05-24 1984-05-24 Contraceptive for animals WO1984004666A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8308486A FR2546400B1 (en) 1983-05-24 1983-05-24 CONTRACEPTIVE FOR ANIMALS

Publications (1)

Publication Number Publication Date
WO1984004666A1 true WO1984004666A1 (en) 1984-12-06

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/FR1984/000137 WO1984004666A1 (en) 1983-05-24 1984-05-24 Contraceptive for animals

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Country Link
EP (1) EP0158639A1 (en)
FR (1) FR2546400B1 (en)
WO (1) WO1984004666A1 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5269321A (en) * 1991-01-16 1993-12-14 Controlled Therapeutics (Scotland) Ltd. Retrievable pessary

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2151397B1 (en) * 1998-06-03 2001-07-01 Martinez Moreno Julio Fernando APPLICATION UNIT OF A DOSE OF CHEMICAL AND SIMILAR PRODUCTS.

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3780730A (en) * 1971-05-28 1973-12-25 A Weisman Contraceptive
FR2224119A1 (en) * 1973-04-05 1974-10-31 Dickinson Ben
US3975350A (en) * 1972-08-02 1976-08-17 Princeton Polymer Laboratories, Incorporated Hydrophilic or hydrogel carrier systems such as coatings, body implants and other articles
US4086333A (en) * 1976-01-05 1978-04-25 Claudia Bredwell Method of eliminating sexual excitants from the discharge of a female animal in estrus
US4271835A (en) * 1978-05-17 1981-06-09 Kcdp Corporation Fluid-expansible contraceptive tampon and applicator
US4369773A (en) * 1980-11-05 1983-01-25 Milos Chvapil Contraceptive sponge - diaphragm bilayer

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3780730A (en) * 1971-05-28 1973-12-25 A Weisman Contraceptive
US3975350A (en) * 1972-08-02 1976-08-17 Princeton Polymer Laboratories, Incorporated Hydrophilic or hydrogel carrier systems such as coatings, body implants and other articles
FR2224119A1 (en) * 1973-04-05 1974-10-31 Dickinson Ben
US4086333A (en) * 1976-01-05 1978-04-25 Claudia Bredwell Method of eliminating sexual excitants from the discharge of a female animal in estrus
US4271835A (en) * 1978-05-17 1981-06-09 Kcdp Corporation Fluid-expansible contraceptive tampon and applicator
US4369773A (en) * 1980-11-05 1983-01-25 Milos Chvapil Contraceptive sponge - diaphragm bilayer

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5269321A (en) * 1991-01-16 1993-12-14 Controlled Therapeutics (Scotland) Ltd. Retrievable pessary
EP0577891A1 (en) * 1991-01-16 1994-01-12 Btg International Limited Retrievable pessary

Also Published As

Publication number Publication date
FR2546400A1 (en) 1984-11-30
EP0158639A1 (en) 1985-10-23
FR2546400B1 (en) 1987-05-22

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