FIG. 1 is a side perspective view of a wrist brace with adjustable thumb closure, showing my new design, in use condition on a left hand;

FIG. 2 is a side perspective view thereof, in use condition on a right hand;

FIG. 3 is an outside view thereof, in open condition; and,

FIG. 4 is an inside view thereof; in open condition.

The broken line showing is for illustrative purposes only and forms no part of the claimed design.