|Publication number||US7957440 B2|
|Application number||US 12/028,817|
|Publication date||7 Jun 2011|
|Filing date||10 Feb 2008|
|Priority date||27 Jul 2004|
|Also published as||CA2575443A1, CA2575443C, CN101432102A, EP1799404A2, EP1799404A4, US7630420, US20060126680, US20080212624, WO2006012461A2, WO2006012461A3, WO2006012461A9, WO2006015151A2, WO2006015151A3|
|Publication number||028817, 12028817, US 7957440 B2, US 7957440B2, US-B2-7957440, US7957440 B2, US7957440B2|
|Original Assignee||Biolase Technology, Inc.|
|Patent Citations (105), Non-Patent Citations (21), Referenced by (1), Classifications (17), Legal Events (5) |
|External Links: USPTO, USPTO Assignment, Espacenet|
Dual pulse-width medical laser
US 7957440 B2
A laser device that includes a dual pulse-width laser-pumping circuit generates long and short laser pulses. The laser-pumping circuit employs a single power supply with dual high voltage outputs that are selectable under control of a user. The laser device conveniently generates long and short laser pulses or a mix of the two for performing specialized surgical procedures.
1. A method of generating dual pulse outputs for an electromagnetic energy output device, the method comprising:
providing a first high voltage output from a power supply, the first high voltage output being capable of driving, with a first potential, a first pulse-forming network that is configured to generate a first pulse output having a first duration;
providing a second high voltage output from the power supply, the second high voltage output being capable of driving, with a second potential smaller than the first potential, a pulse-forming network that is configured differently to generate responsive to an input a second pulse output having one or more of a greater duration and lower-power relative to a pulse output generated by the first-pulse forming network;
providing a laser-pumping source capable of being pumped by at least one of the first pulse output from the first pulse-forming network and the second pulse output from the second pulse-forming network, whereby (a) the first high voltage output is greater than the second high voltage output, (b) the first pulse-forming network comprises a capacitance that is less than a corresponding capacitance of the second pulse forming network, (c) the first pulse-forming network comprises an inductance that is greater than a corresponding inductance of the second pulse-forming network, (d) a laser pulse having a first duration results by pumping the laser-pumping source with the first pulse output, (e) a laser pulse having a second duration results by pumping the laser-pumping source with the second pulse output; and
outputting laser pulses of the first and second different durations and fluid to a tissue to obtain, respectively, first and second different cutting effects;
whereby the amount of fluid is varied with the first and second durations to obtain the different first and second cutting effects.
2. The method as set forth in claim 1, further comprising generating a plurality of laser pulses by repetitively pumping the laser-pumping source with the first pulse output.
3. The method as set forth in claim 1, further comprising generating a plurality of laser pulses by repetitively pumping the laser-pumping source with the second pulse output.
4. The method as set forth in claim 1, further comprising generating a plurality of laser pulses, each laser pulse having one of a first duration generated by pumping the laser-pumping source with the first pulse output and a second, greater duration generated by pumping the laser-pumping source with the second pulse output.
5. The method as set forth in claim 4
, further comprising:
receiving a control input from a user; and
controlling the generating of laser pulses according to the control input.
6. The method as set forth in claim 1
the generating of a pulse having a first duration comprises generating a pulse having a duration of about 50 microseconds; and
the generating of a pulse having a second duration comprises generating a pulse having duration of about 1000 microseconds.
7. The method as set forth in claim 1
the providing of a first high voltage output comprises providing a voltage of about 1500 volts; and
the providing of a second high voltage output comprises providing a voltage of about 500 volts.
CROSS-REFERENCE TO RELATED APPLICATIONS
This application is a divisional of U.S. application Ser. No. 11/191,594, filed Jul. 27, 2005, now U.S. Pat. No. 7,630,420 the entire contents of which are incorporated herein by reference.
BACKGROUND OF THE INVENTION
1. Field of the Invention
The present invention relates generally to electromagnetic energy emitting devices and, more particularly, to pulsed medical treatment laser devices.
2. Description of Related Art
A variety of electromagnetic laser energy generating architectures have existed in the prior art. A solid-state laser system, for example, generally comprises a laser rod for emitting coherent light and a source for stimulating the laser rod to emit the coherent light. Flashlamps are typically used as stimulation sources for middle infrared lasers between 2.5 microns (μm) and 3.5 μm, such as Er, Cr:YSGG and Er:YAG laser systems. The flashlamp is driven by a flashlamp current, which comprises a predetermined pulse shape and a predetermined frequency.
The flashlamp current drives the flashlamp at the predetermined frequency, to thereby produce an output flashlamp light distribution having substantially the same frequency as the flashlamp current. This output flashlamp light distribution from the flashlamp drives the laser rod to produce coherent light at substantially the same predetermined frequency as the flashlamp current.
Medical applications, such as those requiring the excision of soft human tissue, may in some instances require or benefit from two opposite tissue effects. The first effect may relate to laser cutting of tissue with controlled hemostasis, minimal to no bleeding, and attenuated or eliminated charring of cut surfaces. The second effect may relate to laser cutting with bleeding in order, for example, to stimulate post-operative healing when tissue is brought together. The second effect can be particularly important or relevant, for example, in grafting applications.
Prior art methods of generating these first and second effects can include employing distinctly different devices for each type of tissue cutting. Some prior art methods of performing first and second effect procedures may include employing systems capable of generating different wavelengths of laser energy. For example, wavelengths of about 1 μm and about 3 μm may be generated using CO2 and Erbium type lasers, respectively. Overhead time and effort that may be required in switching between two medical devices can be disadvantages of this approach. Extra time and attendant discomfort from a point of view of a patient undergoing such procedures may represent additional disadvantages.
A need exists in the prior art for laser devices capable of rapidly and efficiently transitioning between varying characteristics or modes of operation, to facilitate, for example, different desired cutting effects or procedures such as for facilitating both hemostatic-type and bleeding-type tissue cutting effects
SUMMARY OF THE INVENTION
An exemplary implementation of the method present invention addresses these needs by providing first and second high voltage outputs from a single power supply. A laser-pumping source (e.g., a flashlamp) also can be provided, the laser-pumping source being capable of exciting a laser that may be used for cutting tissue. The first and second high voltage outputs drive respective first and second pulse-forming networks capable of generating respective first and second pulse outputs that pump the laser-pumping source according to the exemplary implementation of the method. Pulses produced by the first pulse-forming network may be relatively short, and pulses produced by the second pulse-forming network may be relatively long.
An embodiment of the present invention comprises a laser device having a single power supply capable of supplying a first high voltage output at a first voltage level and a second high voltage output at a second voltage level. The embodiment further comprises a laser-pumping source and first and second pulse-forming networks. The respective first and second pulse-forming networks are capable of receiving respective first and second high voltage outputs and are further capable of driving the laser-pumping source.
While the apparatus and method has or will be described for the sake of grammatical fluidity with functional explanations, it is to be expressly understood that the claims, unless expressly formulated under 35 U.S.C. 112, are not to be construed as necessarily limited in any way by the construction of “means” or “steps” limitations, but are to be accorded the full scope of the meaning and equivalents of the definition provided by the claims under the judicial doctrine of equivalents, and in the case where the claims are expressly formulated under 35 U.S.C. 112 are to be accorded full statutory equivalents under 35 U.S.C. 112.
Any feature or combination of features described herein are included within the scope of the present invention provided that the features included in any such combination are not mutually inconsistent as will be apparent from the context, this specification, and the knowledge of one skilled in the art. For purposes of summarizing the present invention, certain aspects, advantages and novel features of the present invention are described herein. Of course, it is to be understood that not necessarily all such aspects, advantages or features will be embodied in any particular embodiment of the present invention. Additional advantages and aspects of the present invention are apparent in the following detailed description and claims that follow.
BRIEF DESCRIPTION OF THE FIGURES
FIG. 1 is a flow diagram describing an implementation of the method of the present invention;
FIG. 2 is a schematic diagram illustrating an embodiment of a dual pulse-width flashlamp driving circuit;
FIG. 3 is a plot depicting short, long, and mixed laser pulses generated by the dual pulse-width flashlamp driving circuit shown in FIG. 2; and
FIG. 4 is a block diagram showing a fluid output used in combination with an electromagnetic energy source having a flashlamp driving circuit in accordance with the present invention.
DETAILED DESCRIPTION OF THE INVENTION
Reference will now be made in detail to the presently preferred embodiments of the invention, examples of which are illustrated in the accompanying drawings. Wherever possible, the same or similar reference numbers are used in the drawings and the description to refer to the same or like parts. It should be noted that the drawings are in simplified form and are not to precise scale. In reference to the disclosure herein, for purposes of convenience and clarity only, directional terms, such as, top, bottom, left, right, up, down, over, above, below, beneath, rear, and front, are used with respect to the accompanying drawings. Such directional terms should not be construed to limit the scope of the invention in any manner.
Although the disclosure herein refers to certain illustrated embodiments, it is to be understood that these embodiments are presented by way of example and not by way of limitation. The intent of the following detailed description, although discussing exemplary embodiments, is to be construed to cover all modifications, alternatives, and equivalents of the embodiments as may fall within the spirit and scope of the invention as defined by the appended claims. It is to be understood and appreciated that the process steps and structures described herein do not cover a complete architecture and process flow for operation of laser devices. The present invention may be practiced in conjunction with various structures and techniques that are conventionally used in the art, and only so much of the commonly practiced items are included herein as are necessary to provide an understanding of the present invention. The present invention has applicability in the field of electromagnetic treatment devices in general. For illustrative purposes, however, the following description pertains to a medical laser device and a method of operating the medical laser device to perform tissue treatments and surgical functions.
Referring more particularly to the drawings, FIG. 1 is a flow diagram describing an implementation of the method of the present invention. This implementation of the method provides a first high voltage output from a high voltage power supply (HVPS) at step 10. The first high voltage output is capable of driving a first pulse-forming network (PFN). A second high voltage output from the HVPS is provided at step 15. The second high voltage output is capable of driving a second pulse-forming network. An exemplary embodiment of the high voltage outputs described herein can provide about 1500 volts from the first high voltage output and about 500 volts from the second high voltage output. A laser-pumping source is further provided at step 20 according to the implementation. In a representative embodiment, the laser-pumping source can comprise a flashlamp capable of stimulating emission of coherent light by a laser device such as, for example, an Er:YSGG or Er, Cr:YSGG solid state laser. At step 25 of the implementation, a laser pulse having a first duration is generated by pumping the laser-pumping source with the first pulse-forming network output. Similarly, at step 30 a laser pulse having a second duration may be generated by pumping the laser-pumping source with the second pulse-forming network output.
An example of a circuit capable of driving a flashlamp from first and second high voltage outputs is described below with reference to FIG. 2. A relatively detailed implementation of the circuit of FIG. 2 is disclosed in FIGS. 2 p and 3 p of the above-referenced U.S. Provisional Application No. 60/591,933, filed Jul. 27, 2004 and entitled DUAL PULSE-WIDTH MEDICAL LASER. An Er:YSGG or Er, Cr:YSGG solid state laser, which is capable of generating electromagnetic energy having a wavelength in a range of about 2.70 microns (μm) to 2.80 μm, typically 2.78 μm, may be driven with the architecture of this circuit. Parameters of the first and second pulse-forming networks may be adjusted to produce, respectively, pulses having relatively short and long durations. In a typical embodiment, relatively short pulses having durations of, for example, about 140 microseconds (μs) are produced by the first pulse-forming network, and relatively long pulses having durations of, for example, about 400 μs are produced by the second pulse-forming network. Repetition rates for the pulses may range, for example, from about 1 to 50 pulses/second.
A partial schematic diagram of an embodiment of a dual pulse-width analog flashlamp driving circuit 100 according to the present invention is shown in FIG. 2, comprising a high voltage power supply 105 capable of producing dual, i.e., respective first and second, high voltage outputs 110 and 130 using methods known to those skilled in the art. In the illustrated embodiment, the first and second high voltage outputs 110 and 130 are provided on different nodes so that they may be generated at different times or have different values. The illustrated embodiment of the dual pulse-width analog flashlamp driving circuit 100 further comprises a first pulse-forming network 101 and a second pulse-forming network 102 connected to respective first and second high voltage outputs 110 and 130. First and second pulse-forming networks 101 and 102 are further connected to a flashlamp 150 that may function as a pumping source for a laser (not shown).
The first pulse-forming network 101 in the illustrated embodiment comprises a first capacitor 115, a first switching transistor 120, (for example, an insulated gate bipolar transistor (IGBT)), and a first inductor 125. The first capacitor 115 is connected between the first high voltage output 110 and ground. The first high voltage output 110 further is connected to the first inductor 125 through the first switching transistor 120, and the flashlamp 150 is electrically connected between the first inductor 125 and ground. The first pulse-forming network 101 and the second pulse-forming network 102 may be similar in form to a circuit such as that shown in FIG. 3 of the above-referenced U.S. application Ser. No. 11/033,032 filed Jan. 10, 2005 and entitled ELECTROMAGNETIC ENERGY DISTRIBUTIONS FOR ELECTROMAGNETICALLY INDUCED MECHANICAL CUTTING. The second pulse-forming network 102, which is similar in form to the first pulse-forming network 101, comprises a second capacitor 135, a second switching transistor 140, and a second inductor 145. The second high voltage output 130 is applied to a terminal of the second capacitor 135, which has another terminal connected to ground. The second high voltage output 130 also is coupled through a second switching transistor 140 to the second inductor 145, which is connected to the flashlamp 150.
In typical embodiments of the dual pulse-width analog flashlamp driving circuit 100, first and second capacitors 115 and 135 may assume values of, respectively, about 30 microfarads (μF) to about 70 μF, with an exemplary value being about 50 μF, and about 300 μF to about 600 μF, with an exemplary value being about 400 μF. First and second capacitors may receive respective first and second high voltage outputs 110 and 130. The first high voltage output 110 in an illustrative embodiment has a value ranging from about 1200 volts to about 1500 volts at an impedance level capable of charging the first capacitor 115 at a rate of about 1500 Joules per second (J/s). The second high voltage output 130 in the embodiment may range from about 200 volts to about 500 volts at an impedance level capable of charging the second capacitor 135 at a rate of about 1 J/s. The first inductor 125 may comprise an inductance of about 30 microhenries (μH) to about 70 μH, such as a solid core inductor having a rated inductance of about 50 μH in an exemplary embodiment. The second inductor 145 may comprise an inductance of about 800 μH to about 1200 μH, such as a solid core inductor having an inductance of about 1 millihenry (mH). The flashlamp 150 may comprise a 450 to 900 torr source, such as a 700 torr source. Control signals 155 and 160 from a control device 165 may be applied to terminals of transistors 120 and 140 in order to enable operation of the first pulse-forming network 101 or the second pulse-forming network 102. Enabling the first pulse-forming network 101 may generate relatively short laser pulses, and enabling the second pulse-forming network 102 may generate relatively long laser pulses according to a typical mode of operation of the illustrated embodiment. A user input 170, which may comprise, for example, a switch on a laser handset (not shown), may specify parameters (e.g., user adjustable parameters) such as pulse duration and/or pulse repetition rate. In some embodiments, additional switching transistors 121 and 141, shown in phantom in FIG. 2, may be provided in order to increase current capacity of the first and second pulse-forming networks 101 and 102.
A relatively short current pulse 175 may be produced by the first pulse-forming network 101 in the embodiment of the dual pulse-width analog flashlamp driving circuit 100 illustrated in FIG. 2. The second pulse-forming network 102 may produce a relatively long current pulse 180 with parameters chosen substantially as described herein.
FIG. 3 is a chart illustrating three exemplary chains (a, b, c) of laser pulses capable of being produced by a laser device driven by the dual pulse-width analog flashlamp driving circuit embodiment 100 shown in FIG. 2. Chain (a) illustrates laser energy generated according to relatively long pulses. Chain (b) illustrates relatively short pulses of laser energy, and chain (c) depicts a mixture of relatively long and short pulses. A user may select a type of pulse chain to be produced using, for example, a user input 170 (FIG. 2).
Long pulses generated by the embodiment illustrated in FIG. 2 may be used to achieve an objective of cutting tissue with good hemostasis, no bleeding, and no charring of a cut surface. Conversely, short pulses generated by the same embodiment may provide for cutting with bleeding in order to promote post-operative healing. In another application, short pulses may be employed in the cutting of hard tissue (e.g., tooth enamel, dentin, bone) while long pulses may be used in cutting soft tissue (e.g., periodontal, mucosa, liver, kidney) and to perform thermal modifications. Examples of long pulse and short pulse applications are described in, for example, U.S. application Ser. No. 11/033,032, filed Jan. 10, 2005 and entitled ELECTROMAGNETIC ENERGY DISTRIBUTION FOR ELECTROMAGNETICALLY INDUCED MECHANICAL CUTTING and U.S. Provisional Application No. 60/601,415, filed Aug. 13, 2004 and entitled DUAL PULSE-WIDTH MEDICAL LASER WITH PRESETS. Indication, for instance, pulses of greater power for hard tissue application. According to certain implementations of the present invention, use of the methods and apparatus described herein are not restricted to medical (or dental) applications alone, and similar methods and apparatus contemplated by the present invention may be applied in industrial applications, such as for removing and shaping semiconductor materials.
Corresponding or related structure and methods described in the following patents assigned to BioLase Technology, Inc., are incorporated herein by reference in their entireties, wherein such incorporation includes corresponding or related structure (and modifications thereof) in the following patents which may be (i) operable with, (ii) modified by one skilled in the art to be operable with, and/or (iii) implemented/used with or in combination with any part(s) of, the present invention according to this disclosure, that/those of the patents, and the knowledge and judgment of one skilled in the art: U.S. Pat. No. 5,741,247; U.S. Pat. No. 5,785,521; U.S. Pat. No. 5,968,037; U.S. Pat. No. 6,086,367; U.S. Pat. No. 6,231,567; U.S. Pat. No. 6,254,597; U.S. Pat. No. 6,288,499; U.S. Pat. No. 6,350,123; U.S. Pat. No. 6,389,193; U.S. Pat. No. 6,544,256; U.S. Pat. No. 6,561,803; U.S. Pat. No. 6,567,582; U.S. Pat. No. 6,610,053; U.S. Pat. No. 6,616,447; U.S. Pat. No. 6,616,451; U.S. Pat. No. 6,669,685; U.S. Pat. No. 6,744,790 and U.S. Pat. No. 6,821,272. For example, output optical energy distributions 60 from the flashlamp 150 of the illustrated embodiment of the present invention may be useful for optimizing or maximizing a cutting effect of an electromagnetic energy source 32, such as a laser that is driven by the flashlamp 150. The laser output can be directed, for example, into fluid (e.g., an atomized distribution of fluid particles) 34 above a target surface 36, as shown in FIG. 4. An apparatus for directing electromagnetic energy into an atomized distribution of fluid particles above a target surface is disclosed in the above-referenced U.S. Pat. No. 5,741,247. As disclosed at column 4, lines 31 and 43 and FIG. 3, this document discloses pulse durations (i.e., pulse widths) having different durations (i.e., a first pulse shorter than a second pulse). The long and/or short pulses can impart large amounts of energy into the fluid (e.g., atomized fluid particles) which preferably comprises water, to thereby expand the fluid (e.g., fluid particles) and apply disruptive (e.g., mechanical) cutting forces to the target surface.
In view of the foregoing, it will be understood by those skilled in the art that the methods of the present invention can facilitate operation of laser devices, and in particular medical laser devices exhibiting a capability of producing laser pulses having a plurality of pulse durations. The above-described embodiments have been provided by way of example, and the present invention is not limited to these examples. Multiple variations and modification to the disclosed embodiments will occur, to the extent not mutually exclusive, to those skilled in the art upon consideration of the foregoing description.
For example, a laser-pumping circuit comprising a plurality (e.g., more than two) of high voltage outputs and corresponding pulse-forming networks (e.g., for generating three or more outputs of varying pulse width) is contemplated by the present invention. The present invention may be used with or constructed to implement different laser pulse durations and varying amounts of fluid (e.g., water streams, sprays or mists) in the context of, for example, Erbium-types of lasers, for facilitating, for example, multiple treatment or cutting effects such as hemostatic-type and bleeding-type tissue cutting effects. For example, a wavelength of about 3 μm and pulse durations of 50 μs and 1000 μs may be implemented to provide first and second cutting effects as desired.
The present invention may also be used or constructed with capacitor-charging power supplies in the generation of pulses having variable duration, keeping in mind that such modifications may in some instances present issues such as limited pulse repetition rates, relatively expensive driving circuitry, somewhat rectangular rather than bell-shaped current pulse shapes, and relatively numerous, voluminous and/or heavy capacitors.
While the invention has been described in the context of first and second pulse-forming networks, it is to be understood that greater numbers of pulse-forming networks, each similar to the first and second pulse-forming networks but being constructed for generating pulses of different lengths, are also contemplated. Moreover, while the invention has been described in the context of using a single power supply to generate two pulse outputs for an electromagnetic energy output device, implementations of the present invention using three or more pulse-forming networks may comprise a single power supply or may comprise a number of power supplies that is less than the number of pulse-forming networks.
Additionally, other combinations, omissions, substitutions and modifications will be apparent to the skilled artisan in view of the disclosure herein. Accordingly, the present invention is not intended to be limited by the disclosed embodiments, but is to be defined by reference to the appended claims.
|Cited Patent||Filing date||Publication date||Applicant||Title|
|US3051906 *||26 May 1958||28 Aug 1962||Itt||Pulse waveform synthesizer using plurality of individually charged storage means sequentially discharged through common load|
|US3679863||10 Nov 1969||25 Jul 1972||Nat Res Dev||Thermal cutting apparatus|
|US3679998||21 Jan 1971||25 Jul 1972||Hughes Aircraft Co||Laser flashtube triggering arrangement|
|US3914648||10 May 1974||21 Oct 1975||Avco Everett Res Lab Inc||Flashlamp discharge circuit|
|US3991296||12 Nov 1975||9 Nov 1976||Nippon Electric Company, Ltd.||Apparatus for forming grooves on a wafer by use of a laser|
|US4005333||3 Jun 1974||25 Jan 1977||Hughes Aircraft Company||Apparatus for increasing output efficiency of an optically pumped Nd:YAG laser|
|US4087705 *||10 Feb 1977||2 May 1978||Ritter Corporation||High power variable pulse width triggering circuits|
|US4092864||4 Aug 1976||6 Jun 1978||Qualitrol Corporation||Hot spot thermometer|
|US4276518||1 May 1978||30 Jun 1981||The United States Of America As Represented By The Secretary Of The Navy||Optical oscillator|
|US4550275||7 Oct 1983||29 Oct 1985||The United States Of America As Represented By The Secretary Of The Air Force||High efficiency pulse ultraviolet light source|
|US4724299||15 Apr 1987||9 Feb 1988||Quantum Laser Corporation||Laser spray nozzle and method|
|US4770811||22 Mar 1985||13 Sep 1988||Kigre, Inc.||Sensitized laser glass|
|US4826431||11 Jun 1987||2 May 1989||Kabushiki Kaisha Morita Seisakusho||Medical laser handpiece|
|US4862888||9 Sep 1988||5 Sep 1989||Bausch & Lomb Incorporated||Laser system|
|US4908030||29 Apr 1987||13 Mar 1990||Vent-Plant Corporation, Inc.||Method of manufacturing synthetic bone coated surgical implants|
|US4910438||17 Dec 1985||20 Mar 1990||Hughes Aircraft Company||Wide band, high efficiency simmer power supply for a laser flashlamp|
|US4913142||26 May 1987||3 Apr 1990||Massachusetts Institute Of Technology||Catheter for laser angiosurgery|
|US4931047||30 Sep 1987||5 Jun 1990||Cavitron, Inc.||Method and apparatus for providing enhanced tissue fragmentation and/or hemostasis|
|US4985027||26 Feb 1990||15 Jan 1991||Dressel Thomas D||Soft tissue aspiration device and method|
|US5086378||20 Aug 1990||4 Feb 1992||Prince Mark W||Fiber optic finger light|
|US5092773||20 Nov 1990||3 Mar 1992||Endo Technic Corporation||Method and apparatus for filling a tooth canal|
|US5102410||9 Oct 1990||7 Apr 1992||Dressel Thomas D||Soft tissue cutting aspiration device and method|
|US5151029||30 Oct 1991||29 Sep 1992||Endo Technic Corporation||Removing physiologic tissue from a tooth canal|
|US5199870||7 Apr 1990||6 Apr 1993||Aesculap Ag||Process for destroying and removing material from teeth|
|US5221561||31 Mar 1992||22 Jun 1993||France Telecom, Etablissement Autonome De Droit Public||Process for the photochemical treatment of a material using a flash tube light source|
|US5237331||8 May 1992||17 Aug 1993||Henderson Sammy W||Eyesafe coherent laser radar for velocity and position measurements|
|US5242454||12 Jun 1992||7 Sep 1993||Omega Universal Technologies, Ltd.||Method for diagnosis and shock wave lithotripsy of stones in the submaxillary and parotid glands|
|US5263950||24 Jul 1991||23 Nov 1993||L'esperance Medical Technologies, Inc.||Phaco-extractor for fragmenting cataractous-lens situs of fragmentation|
|US5267856||20 Sep 1991||7 Dec 1993||Premier Laser Systems, Inc.||Laser surgical method|
|US5313481||29 Sep 1993||17 May 1994||The United States Of America As Represented By The United States Department Of Energy||Copper laser modulator driving assembly including a magnetic compression laser|
|US5318562||10 Mar 1992||7 Jun 1994||Laser Endo Technic Corporation||Handpiece for delivering laser radiation|
|US5334019||6 Dec 1991||2 Aug 1994||American Dental Technologies, Inc.||Dental air abrasive system|
|US5374266||25 Nov 1992||20 Dec 1994||Hoya Corporation||Medical laser treatment device|
|US5388988||2 Aug 1993||14 Feb 1995||Siemens Aktiengesellschaft||Dental instrument for treating teeth with a laser beam|
|US5401171||20 Jul 1992||28 Mar 1995||Paghdiwala; Abid F.||Dental laser device and method|
|US5409376||10 Mar 1993||25 Apr 1995||Murphy; Quentin M.||Apparatus and process for laser-assisted driling|
|US5498935 *||12 Nov 1993||12 Mar 1996||William H. McMahan||Laser flash lamp control system|
|US5552675||10 Mar 1992||3 Sep 1996||Lemelson; Jerome H.||High temperature reaction apparatus|
|US5554172||9 May 1995||10 Sep 1996||The Larren Corporation||Directed energy surgical method and assembly|
|US5570182||27 May 1994||29 Oct 1996||Regents Of The University Of California||Method for detection of dental caries and periodontal disease using optical imaging|
|US5574247||21 Jun 1994||12 Nov 1996||Hitachi, Ltd.||CVD reactor apparatus|
|US5611797||26 Jul 1995||18 Mar 1997||Virginia C. George||Combination handpiece and surgical laser tool|
|US5694046||27 Nov 1995||2 Dec 1997||Precitec Gmbh||Method and apparatus for monitoring thermal processing of a workpiece in accordance with a measured capacitance frequency distribution|
|US5723864||3 Jul 1996||3 Mar 1998||Innovative Lasers Corporation||Linear cavity laser system for ultra-sensitive gas detection via intracavity laser spectroscopy (ILS)|
|US5729562||31 Oct 1996||17 Mar 1998||Advanced Pulse Power Technologies, Inc.||Pulse power generating circuit with energy recovery|
|US5741247 *||31 Aug 1995||21 Apr 1998||Biolase Technology, Inc.||Atomized fluid particles for electromagnetically induced cutting|
|US5755751||7 Jun 1995||26 May 1998||Esc Medical Systems Ltd.||Method and apparatus for therapeutic electromagnetic treatment|
|US5764672||31 Mar 1997||9 Jun 1998||Sony Corporation||Semiconductor laser|
|US5785521||20 Dec 1995||28 Jul 1998||Biolase Technology, Inc.||Fluid conditioning system|
|US5820627||28 Mar 1996||13 Oct 1998||Physical Sciences, Inc.||Real-time optical feedback control of laser lithotripsy|
|US5825958||11 Oct 1996||20 Oct 1998||Pharos Optics, Inc.||Fiber optic delivery system for infrared lasers|
|US5828803||6 Mar 1995||27 Oct 1998||Esc Medical Systems, Ltd.||System for providing pulsed light to an optical fiber|
|US5869805||4 Aug 1995||9 Feb 1999||Fraunhofer-Gesellschaft Zur Forderung Der Angewandten Forschung E.V.||Method and device for working materials using plasma-inducing laser radiation|
|US5968037||5 Dec 1997||19 Oct 1999||Biolase Technology, Inc.||User programmable combination of atomized particles for electromagnetically induced cutting|
|US6080148||18 Nov 1996||27 Jun 2000||Trimedyne, Inc.||Variable pulse width lasing device|
|US6083218||10 Jul 1996||4 Jul 2000||Trw Inc.||Method and apparatus for removing dental caries by using laser radiation|
|US6086367||6 Jan 1999||11 Jul 2000||Biolase Technology, Inc.||Dental and medical procedures employing laser radiation|
|US6106516||29 Oct 1998||22 Aug 2000||Sonique Surgical Systems, Inc.||Laser-assisted liposuction method and apparatus|
|US6118521||9 Jul 1998||12 Sep 2000||Lj Laboratories, L.L.C.||Apparatus and method for measuring optical characteristics of an object|
|US6193711||12 Dec 1997||27 Feb 2001||Coherent, Inc.||Rapid pulsed Er:YAG laser|
|US6223987||22 Nov 1999||1 May 2001||Metrologic Instruments, Inc.||Body-wearable automatic laser scanner|
|US6231567||16 Mar 1999||15 May 2001||Biolase Technology Inc.||Material remover and method|
|US6254597||6 Nov 1998||3 Jul 2001||Biolase Technology, Inc.||Tissue remover and method|
|US6288499||12 Jun 1997||11 Sep 2001||Biolase Technology, Inc.||Electromagnetic energy distributions for electromagnetically induced mechanical cutting|
|US6315772||22 Oct 1997||13 Nov 2001||Transmedica International, Inc.||Laser assisted pharmaceutical delivery and fluid removal|
|US6350123||24 Feb 1999||26 Feb 2002||Biolase Technology, Inc.||Fluid conditioning system|
|US6389193||22 Dec 1999||14 May 2002||Biolase Technology, Inc.||Rotating handpiece|
|US6449301||22 Jun 1999||10 Sep 2002||The Regents Of The University Of California||Method and apparatus for mode locking of external cavity semiconductor lasers with saturable Bragg reflectors|
|US6512782||20 Mar 2000||28 Jan 2003||Candela Corporation||Multipulse dye laser|
|US6544256||23 Apr 1999||8 Apr 2003||Biolase Technology, Inc.||Electromagnetically induced cutting with atomized fluid particles for dermatological applications|
|US6561803||27 Nov 2001||13 May 2003||Bioluse Technology||Fluid conditioning system|
|US6567582||30 Mar 2001||20 May 2003||Biolase Tech Inc||Fiber tip fluid output device|
|US6610053||5 Dec 1997||26 Aug 2003||Biolase Technology, Inc.||Methods of using atomized particles for electromagnetically induced cutting|
|US6616447||15 Nov 2001||9 Sep 2003||Biolase Technology, Inc.||Device for dental care and whitening|
|US6616451||19 Jun 1998||9 Sep 2003||Biolase Technology, Inc.||Electromagnetic radiation emitting toothbrush and dentifrice system|
|US6669685||15 Nov 2000||30 Dec 2003||Biolase Technology, Inc.||Tissue remover and method|
|US6701181||31 May 2001||2 Mar 2004||Infraredx, Inc.||Multi-path optical catheter|
|US6744790||21 Jun 2002||1 Jun 2004||Biolase Technology, Inc.||Device for reduction of thermal lensing|
|US6821272||6 Jun 2002||23 Nov 2004||Biolase Technology, Inc||Electromagnetic energy distributions for electromagnetically induced cutting|
|US6878899||27 Jul 2004||12 Apr 2005||Gsi Lumonics Corp.||Laser processing|
|US6902290||1 Aug 2003||7 Jun 2005||R & H Industries, Inc.||Finger-mounted light for variable light output|
|US7097639||20 Jun 2003||29 Aug 2006||Zian Medical, Llc||Dual filter multiple pulse photo-dermatological device with pre/post optical heating, quasi-logarithmic spacing, and laser rod spectrum infusion|
|US20020149324 *||6 Jun 2002||17 Oct 2002||Rizoiu Ioana M.||Electromagnetic energy distributions for electromagnetically induced mechanical cutting|
|US20030069567||19 Sep 2002||10 Apr 2003||Shimon Eckhouse||Method and apparatus for electromagnetic treatment of the skin, including hair depilation|
|US20030100824||23 Aug 2002||29 May 2003||Warren William L.||Architecture tool and methods of use|
|US20030227953 *||20 Dec 2002||11 Dec 2003||Candela Corporation||Multipulse dye laser|
|US20050137655||27 Feb 2004||23 Jun 2005||Macfarland Dean A.||System and method for flexible architecture for dermatologic treatments utilizing multiple light sources|
|US20050143792||24 Dec 2003||30 Jun 2005||Harvey Jay||Hair treatment method|
|US20060020309||1 Apr 2005||26 Jan 2006||Palomar Medical Technologies, Inc.||Methods and products for producing lattices of EMR-treated islets in tissues, and uses therefor|
|DE3840126A1||29 Nov 1988||31 May 1990||Messerschmitt Boelkow Blohm||Protection device for a fibre-coupled laser lithotriptor|
|DE4138468A1||22 Nov 1991||3 Jun 1993||Stiftung Fuer Lasertechnologie||Laser device for removing material from biological surfaces - has liq.-gas spray units which intersect laser sepn. ensuring that surrounding areas are not dehydrated|
|EP0181199A2||6 Nov 1985||14 May 1986||William John Hoskin||Laser knives|
|EP0192833A2||5 Dec 1985||3 Sep 1986||Messerschmitt-Bölkow-Blohm Gesellschaft mit beschränkter Haftung||Method and device for the disintegration of a concretion|
|EP0454312A2||5 Apr 1991||30 Oct 1991||Aurora Laser Inc.||Method and apparatus for laser lithotripsy|
|GB2023330A|| ||Title not available|
|GB2297610A|| ||Title not available|
|JP2003001465A|| ||Title not available|
|JP2003070722A|| ||Title not available|
|JPH05200045A|| ||Title not available|
|JPH05506601A|| ||Title not available|
|JPH11511386A|| ||Title not available|
|JPS5945092A|| ||Title not available|
|WO1990004358A1||23 Oct 1989||3 May 1990||Storz Karl Gmbh & Co||Process and device for breaking up a solid body surrounded by a fluid|
|WO1996041657A1||12 Jun 1996||27 Dec 1996||Nikolai I Tankovich||Laser assisted drug delivery|
|WO1997007928A2||30 Aug 1996||6 Mar 1997||Biolase Tech Inc||User programmable combination of atomized particles for electromagnetically induced cutting|
|1||Bernard Grob, Basic Electronics, Glencoe division of Macmillan/McGraw-Hill, pp. 690-681. 1989.|
|2||European Search Report, Jun. 6, 2005, EP 05 07 5231.|
|3||International Search Report & Written Opinion, Jul. 31, 2006, PCT/US06/00989.|
|4||International Search Report & Written Opinion, Oct. 25, 2006, PCT/US05/28891.|
|5||International Search Report & Written Opinion, Sep. 2, 2005, PCT/US05/00849.|
|6||International Search Report, Dec. 10, 1998, PCT/US98/12357.|
|7||International Search Report, Jun. 30, 2008, PCT/US08/051963.|
|8||International Search Report, May 23, 2008, PCT/US08/051967.|
|9||New Laser-Matter Interaction Concept to Enhance Tissue Cutting Efficiency by loana M. Rizoiu and Larry G. DeShazer, published in SPIE col. 2134A Laser-Tissue Interaction V(1994)/309.|
|10||New Laser—Matter Interaction Concept to Enhance Tissue Cutting Efficiency by loana M. Rizoiu and Larry G. DeShazer, published in SPIE col. 2134A Laser-Tissue Interaction V(1994)/309.|
|11||Partial European Search Report, Apr. 6, 2000, EP 98 92 9060.|
|12||Rizoiu, Ioana and Levy, Guy C. "Efficiency of Bone Ablation with an Nd:YAG Laser Beam Delivered with a Cooling Spray" SPIE vol. 1882 Laser-Tissue Interaction IV (1993), pp. 316-321.|
|13||Rizoiu, loana and Levy, Guy C. "Morphological Changes of Dentin and Enamel after Ablation with an Experimental Laser System" SPIE vol. 2128, pp. 282-288.|
|14||Supplementary European Search Report, EP 05711358 (PCT/US2005/000852), mailed Feb. 8, 2010.|
|15||T.S. Fahlen, Efficient Quarter-Joule KrF Laser with Corona Preionization, IEEE Journal of Quantum Electronics, vol. QE-15, No. 5, pp. 311-312. May 5, 1979.|
|16||U.S. Appl. No. 11/042,824, filed Jan. 24, 2005, Boutoussov, Dmitri.|
|17||U.S. Appl. No. 11/192,334, filed Jul. 27, 2005, Boutoussov, Dmitri.|
|18||U.S. Appl. No. 60/591,933, filed Jul. 27, 2004, Rizoiu, Ioana M.|
|19||U.S. Appl. No. 60/601,415, filed Aug. 13, 2004, Rizoiu, Ioana M.|
|20||U.S. Appl. No. 60/610,757, filed Sep. 18, 2004, Rizoiu, Ioana M.|
|21||Written Opinion, Apr. 15, 1999, PCT/US98/12357.|
|Citing Patent||Filing date||Publication date||Applicant||Title|
|US20110270241 *||11 Jul 2011||3 Nov 2011||Biolase Technology, Inc.||Visual feedback implements for electromagnetic energy output devices|
| || |
|U.S. Classification||372/38.02, 372/30, 606/11, 372/31, 606/10, 372/25, 372/70|
|International Classification||A61B18/18, H01S3/00|
|Cooperative Classification||H01S3/1024, A61B18/20, H01S3/0912, A61B2017/0019, H01S3/092|
|European Classification||H01S3/092, A61B18/20, H01S3/091E|
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