US5482962A - Insecticidal N,N'-disubstituted-N-N'-diacylhydrazines - Google Patents
Insecticidal N,N'-disubstituted-N-N'-diacylhydrazines Download PDFInfo
- Publication number
- US5482962A US5482962A US08/279,132 US27913294A US5482962A US 5482962 A US5482962 A US 5482962A US 27913294 A US27913294 A US 27913294A US 5482962 A US5482962 A US 5482962A
- Authority
- US
- United States
- Prior art keywords
- alkyl
- halo
- alkoxy
- substituted
- independently
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/02—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms
- A01N43/24—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with two or more hetero atoms
- A01N43/32—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with two or more hetero atoms six-membered rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C243/00—Compounds containing chains of nitrogen atoms singly-bound to each other, e.g. hydrazines, triazanes
- C07C243/24—Hydrazines having nitrogen atoms of hydrazine groups acylated by carboxylic acids
- C07C243/38—Hydrazines having nitrogen atoms of hydrazine groups acylated by carboxylic acids with acylating carboxyl groups bound to carbon atoms of six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
- C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
- C07D263/56—Benzoxazoles; Hydrogenated benzoxazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
- C07D277/62—Benzothiazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/82—Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/82—Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D307/83—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
Abstract
Description
TABLE I __________________________________________________________________________ COMPOUNDS OF THIS INVENTION ##STR6## (II) No. Z R.sup.a R.sup.2 B Mp. °C. __________________________________________________________________________ 1 OCHCH H C(CH.sub.3).sub.3 3,5-Dimethylphenyl 176-178 2 OCHCH C.sub.2 H.sub.5 C(CH.sub.3).sub.3 3,5-Dimethylphenyl 105 3 OC(C.sub.2 H.sub.5)CH H C(CH.sub.3).sub.3 3,5-Dimethylphenyl 187-189 4 OCH.sub.2 CH.sub.2 H C(CH.sub.3).sub.3 3,5-Dimethylphenyl 183-184 5 OC(CH.sub.3)CH H C(CH.sub.3).sub.3 3,5-Dimethylphenyl 204-205 6 OC(CH.sub.3).sub.2 CH.sub.2 H C(CH.sub.3).sub.3 3,5-Dimethylphenyl 118 7 OCH.sub.2 CH.sub.2 CH.sub.3 C(CH.sub.3).sub.3 3,5-Dimethylphenyl 125-130 __________________________________________________________________________
TABLE II __________________________________________________________________________ REPRESENTATIVE COMPOUNDS OF THIS INVENTION ##STR7## (I) No. Z R.sup.a R.sup.1 R.sup.2 B __________________________________________________________________________ a SCH.sub.2 CH.sub.2 H H C(CH.sub.3).sub.3 3,5-dimethylphenyl b SCH.sub.2 CH.sub.2 CH.sub.3 H C(CH.sub.3).sub.3 3,5-dimethylphenyl c SCH.sub.2 CH.sub.2 CH.sub.2 CH.sub.3 H C(CH.sub.3).sub.3 3,5-dimethylphenyl d SCH.sub.2 CH.sub.2 CHCH.sub.2 H C(CH.sub.3).sub.3 3,5-dimethylphenyl e OCH.sub.2 CH.sub.2 CH.sub.3 CN C(CH.sub.3).sub.3 3,5-dimethylphenyl f OCHCH CH.sub.3 CN C(CH.sub.3).sub.3 3-chloro-5-methylphenyl g SCHCH CH.sub.3 H C(CH.sub.3).sub.3 3,5-dimethylphenyl h CHCHCH.sub.2 H H C(CH.sub.3).sub.3 3,5-dimethylphenyl i NHCH CH CH.sub.2 CH.sub.3 H C(CH.sub.3).sub.3 3,5-dimethylphenyl j NHCH.sub.2 NH CH.sub.3 H C(CH.sub.3).sub.3 3,5-dimethylphenyl k CH.sub.2 C(O)O H H C(CH.sub.3).sub.3 3,5-dimethylphenyl l OCHN CHCH.sub.2 H C(CH.sub.3).sub.3 3,5-dimethylphenyl m SCH.sub.2 CH.sub.2 CHCH.sub.2 H C(CH.sub.3).sub.2 C.sub.4 H.sub.9 3-methylphenyl n OCH.sub.2 CH.sub.2 CH.sub.3 CN C(CH.sub.3).sub.3 3-chlorophenyl o OCHCH CH.sub.3 CN C(CH.sub.3).sub.3 3-fluorophenyl p SCHCH CH.sub.3 H C.sub.8 H.sub.17 3-fluoro-5-methylphenyl q OCH.sub.2 CH(CH.sub.3) H H C(CH.sub.3).sub.2 C.sub.4 H.sub.9 3-methylphenyl r NHCHCH CH.sub.2 CH.sub.3 H C(CH.sub.3).sub.3 3-chlorophenyl s OCH(CH.sub.3)CH.sub.2 CH.sub.3 H C(CH.sub.3).sub.3 3-fluorophenyl t SCHN H H C.sub.8 H.sub.17 phenyl u OCHN CHCH.sub.2 H C(CH.sub.3).sub.2 C.sub.4 H.sub.9 phenyl v OCH.sub.2 CH.sub.2 CH.sub.3 H C(CH.sub.3).sub.3 phenyl w CH.sub.2 C(CH.sub.2)O H H C(CH.sub.3).sub.3 3,5-dimethylphenyl x OCHCH CH.sub.3 CN C(CH.sub.3).sub.3 3-methoxyphenyl y CF.sub.2 CF.sub.2 O CH.sub.3 H C(CH.sub.3).sub.3 3-chloro-5-methoxyphenyl z C(Cl)CHO CH.sub.2 CH.sub.3 H C(CH.sub.3).sub.3 3-methylphenyl __________________________________________________________________________
Claims (9)
Priority Applications (12)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/279,132 US5482962A (en) | 1994-07-22 | 1994-07-22 | Insecticidal N,N'-disubstituted-N-N'-diacylhydrazines |
EP95304832A EP0693486A1 (en) | 1994-07-22 | 1995-07-11 | Insecticidal N-substituted-N'-(optionally substituted)-N,N'-diacylhydrazines |
IL11454195A IL114541A0 (en) | 1994-07-22 | 1995-07-11 | N-substituted or N,N'-disubstituted-N,N' diacylhydrazines and their use as insecticides |
AU24904/95A AU690990B2 (en) | 1994-07-22 | 1995-07-11 | Insecticidal N,N'-disubstituted-N-N'-diacylhydrazines |
ZA956068A ZA956068B (en) | 1994-07-22 | 1995-07-20 | Insecticidal N-substituted-N'-(optionally substituted)-N,N'-diacylhydrazines |
BR9503404A BR9503404A (en) | 1994-07-22 | 1995-07-21 | Insecticidal compound and composition and process for insect control |
KR1019950021698A KR100394165B1 (en) | 1994-07-22 | 1995-07-21 | Insecticidal N, N'-substituted -N, N'-diacylhydrazine |
JP7206716A JPH0881433A (en) | 1994-07-22 | 1995-07-21 | Insecticidal n,n'-disubstituted n,n'-diacylhydrazine |
CN95108963A CN1119182A (en) | 1994-07-22 | 1995-07-21 | Insecticidal N,N'-disubstituted-N,N'-diacylhydrazines |
TR95/00888A TR199500888A2 (en) | 1994-07-22 | 1995-07-21 | Insecticide n-substituted-n '- (optional substitute) -n, n'-diacilhydrazines. |
HU9502200A HUT73160A (en) | 1994-07-22 | 1995-07-21 | Insecticidal n-substituted-n'(optionally substituted)-n-n'-diacylhidrazines, their use and compositions containing them |
CA002154411A CA2154411A1 (en) | 1994-07-22 | 1995-07-21 | Insecticidal n,n'-disubstituted-n-n'-diacylhydrazines |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/279,132 US5482962A (en) | 1994-07-22 | 1994-07-22 | Insecticidal N,N'-disubstituted-N-N'-diacylhydrazines |
Publications (1)
Publication Number | Publication Date |
---|---|
US5482962A true US5482962A (en) | 1996-01-09 |
Family
ID=23067755
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US08/279,132 Expired - Lifetime US5482962A (en) | 1994-07-22 | 1994-07-22 | Insecticidal N,N'-disubstituted-N-N'-diacylhydrazines |
Country Status (12)
Country | Link |
---|---|
US (1) | US5482962A (en) |
EP (1) | EP0693486A1 (en) |
JP (1) | JPH0881433A (en) |
KR (1) | KR100394165B1 (en) |
CN (1) | CN1119182A (en) |
AU (1) | AU690990B2 (en) |
BR (1) | BR9503404A (en) |
CA (1) | CA2154411A1 (en) |
HU (1) | HUT73160A (en) |
IL (1) | IL114541A0 (en) |
TR (1) | TR199500888A2 (en) |
ZA (1) | ZA956068B (en) |
Cited By (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6177572B1 (en) * | 1997-08-20 | 2001-01-23 | Sepracor, Inc. | Solid and liquid-phase synthesis of benzoxazoles and benzothiazoles and their use |
US20040171651A1 (en) * | 2003-02-21 | 2004-09-02 | Hormann Robert Eugene | Oxadiazoline ligands for modulating the expression of exogenous genes via an ecdysone receptor complex |
US6934494B2 (en) | 2000-09-04 | 2005-08-23 | Canon Kabushiki Kaisha | Driving force receiving member and driving mechanism |
US20050209283A1 (en) * | 2003-02-10 | 2005-09-22 | Hormann Robert E | Diacylhydrazine ligands for modulating the expression of exogenous genes in mammalian systems via an ecdysone receptor complex |
US20060020146A1 (en) * | 2003-02-28 | 2006-01-26 | Hormann Robert E | Bioavailable diacylhydrazine ligands for modulating the expression of exogenous genes via an ecdysone receptor complex |
CN101891708A (en) * | 2009-06-26 | 2010-11-24 | 南开大学 | Diacylhydrazine compounds containing 4-methyl-1,2,3-thiadiazole groups, preparation method and application thereof |
CN1927831B (en) * | 2005-07-06 | 2011-02-09 | 南开大学 | N-sulfenate group diaromatic hydrazide derivative, preparation and application thereof |
WO2014144380A1 (en) * | 2013-03-15 | 2014-09-18 | Intrexon Corporation | Boron-containing diacylhydrazines |
US8884060B2 (en) | 2007-05-29 | 2014-11-11 | Intrexon Corporation | Process of preparing chiral diacylhydrazine ligands |
US9944659B2 (en) | 2014-09-17 | 2018-04-17 | Intrexon Corporation | Boron-containing diacylhydrazine compounds |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6258603B1 (en) * | 1998-06-17 | 2001-07-10 | Rohm And Haas Company | Ligands for modulating the expression of exogenous genes via an ecdysone receptor complex |
DE19831710A1 (en) * | 1998-07-15 | 2000-01-20 | Merck Patent Gmbh | New diacyl-hydrazine derivatives, are integrin inhibitors useful for treating e.g. thrombosis, cardiac infarction, tumors, osteoporosis, inflammation or infection |
CN114835696B (en) * | 2022-05-24 | 2024-03-05 | 贵州医科大学 | Phthalide hydrazide compound and preparation method and application thereof |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB483647A (en) * | 1935-10-25 | 1938-04-19 | Ericsson Telefon Ab L M | Improvements in prepayment meters |
US4857550A (en) * | 1988-08-29 | 1989-08-15 | American Cyanamid Company | Novel insecticidal dibenzoyl-tert-butylcarbazonitrile compounds and method for the preparation thereof |
US5117057A (en) * | 1985-10-21 | 1992-05-26 | Rohm And Haas Company | Insecticidal N' substituted-N-N'-disubstituted-hydrazines |
JPH04235177A (en) * | 1991-01-09 | 1992-08-24 | Nippon Kayaku Co Ltd | New hydrazine derivative and insecticidal composition containing the same derivative as active ingredient |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK483586A (en) * | 1985-10-21 | 1987-04-22 | Rohm & Haas | INSECTICIDE N'-SUBSTITUTED-N, N'-DIACYL HYDRAZINES |
JPH03141245A (en) * | 1989-10-24 | 1991-06-17 | Ishihara Sangyo Kaisha Ltd | Hydrazine-based compound, production thereof and controlling agent against noxious animal containing the same |
NZ240155A (en) * | 1990-10-29 | 1992-10-28 | Ishihara Sangyo Kaisha | Heterocyclyl acyl and (hexahydro) indanyl acyl substituted hydrazine derivatives, preparation thereof and pesticidal compositions |
-
1994
- 1994-07-22 US US08/279,132 patent/US5482962A/en not_active Expired - Lifetime
-
1995
- 1995-07-11 EP EP95304832A patent/EP0693486A1/en not_active Withdrawn
- 1995-07-11 AU AU24904/95A patent/AU690990B2/en not_active Expired
- 1995-07-11 IL IL11454195A patent/IL114541A0/en unknown
- 1995-07-20 ZA ZA956068A patent/ZA956068B/en unknown
- 1995-07-21 KR KR1019950021698A patent/KR100394165B1/en not_active IP Right Cessation
- 1995-07-21 TR TR95/00888A patent/TR199500888A2/en unknown
- 1995-07-21 CN CN95108963A patent/CN1119182A/en active Pending
- 1995-07-21 HU HU9502200A patent/HUT73160A/en unknown
- 1995-07-21 BR BR9503404A patent/BR9503404A/en not_active IP Right Cessation
- 1995-07-21 JP JP7206716A patent/JPH0881433A/en active Pending
- 1995-07-21 CA CA002154411A patent/CA2154411A1/en not_active Abandoned
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB483647A (en) * | 1935-10-25 | 1938-04-19 | Ericsson Telefon Ab L M | Improvements in prepayment meters |
US5117057A (en) * | 1985-10-21 | 1992-05-26 | Rohm And Haas Company | Insecticidal N' substituted-N-N'-disubstituted-hydrazines |
US4857550A (en) * | 1988-08-29 | 1989-08-15 | American Cyanamid Company | Novel insecticidal dibenzoyl-tert-butylcarbazonitrile compounds and method for the preparation thereof |
JPH04235177A (en) * | 1991-01-09 | 1992-08-24 | Nippon Kayaku Co Ltd | New hydrazine derivative and insecticidal composition containing the same derivative as active ingredient |
Cited By (33)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6177572B1 (en) * | 1997-08-20 | 2001-01-23 | Sepracor, Inc. | Solid and liquid-phase synthesis of benzoxazoles and benzothiazoles and their use |
US6934494B2 (en) | 2000-09-04 | 2005-08-23 | Canon Kabushiki Kaisha | Driving force receiving member and driving mechanism |
US9272986B2 (en) | 2003-02-10 | 2016-03-01 | Intrexon Corporation | Diacylhydrazine ligands for modulating the expression of exogenous genes in mammalian systems via an ecdysone receptor complex |
US8748125B2 (en) | 2003-02-10 | 2014-06-10 | Intrexon Corporation | Diacylhydrazine ligands for modulating the expression of exogenous genes in mammalian systems via an ecdysone receptor complex |
US7304161B2 (en) | 2003-02-10 | 2007-12-04 | Intrexon Corporation | Diaclhydrazine ligands for modulating the expression of exogenous genes in mammalian systems via an ecdysone receptor complex |
US20050209283A1 (en) * | 2003-02-10 | 2005-09-22 | Hormann Robert E | Diacylhydrazine ligands for modulating the expression of exogenous genes in mammalian systems via an ecdysone receptor complex |
US7851220B2 (en) | 2003-02-10 | 2010-12-14 | Intrexon Corporation | Diacylhydrazine ligands for modulating the expression of exogenous genes in mammalian systems via an ecdysone receptor complex |
US8669072B2 (en) | 2003-02-21 | 2014-03-11 | Intrexon Corporation | Oxadiazoline ligands for modulating the expression of exogenous genes via an ecdysone receptor complex |
US7304162B2 (en) | 2003-02-21 | 2007-12-04 | Intrexon Corporation | Oxadiazoline ligands for modulating the expression of exogenous genes via an ecdysone receptor complex |
US20070287731A1 (en) * | 2003-02-21 | 2007-12-13 | Hormann Robert E | Oxadiazoline ligands for modulating the expression of exogenous genes via an ecdysone receptor complex |
US20040171651A1 (en) * | 2003-02-21 | 2004-09-02 | Hormann Robert Eugene | Oxadiazoline ligands for modulating the expression of exogenous genes via an ecdysone receptor complex |
US20090149514A1 (en) * | 2003-02-21 | 2009-06-11 | Intrexon Corporation | Oxadiazoline ligands for modulating the expression of exogenous genes via an ecdysone receptor complex |
US8895306B2 (en) | 2003-02-21 | 2014-11-25 | Intrexon Corporation | Oxadiazoline ligands for modulating the expression of exogenous genes via an ecdysone receptor complex |
US7563928B2 (en) | 2003-02-28 | 2009-07-21 | Intrexon Corporation | Bioavailable diacylhydrazine ligands for modulating the expression of exogenous genes via an ecdysone receptor complex |
US9359289B2 (en) | 2003-02-28 | 2016-06-07 | Intrexon Corporation | Bioavailable diacylhydrazine ligands for modulating the expression of exogenous genes via an ecdysone receptor complex |
US20060020146A1 (en) * | 2003-02-28 | 2006-01-26 | Hormann Robert E | Bioavailable diacylhydrazine ligands for modulating the expression of exogenous genes via an ecdysone receptor complex |
US8524948B2 (en) | 2003-02-28 | 2013-09-03 | Intrexon Corporation | Bioavailable diacylhydrazine ligands for modulating the expression of exogenous genes via an ecdysone receptor complex |
US9102648B1 (en) | 2003-02-28 | 2015-08-11 | Intrexon Corporation | Bioavailable diacylhydrazine ligands for modulating the expression of exogenous genes via an ecdysone receptor complex |
US9169210B2 (en) | 2003-02-28 | 2015-10-27 | Intrexon Corporation | Bioavailable diacylhydrazine ligands for modulating the expression of exogenous genes via an ecdysone receptor complex |
US9255273B2 (en) | 2003-02-28 | 2016-02-09 | Intrexon Corporation | Bioavailable diacylhydrazine ligands for modulating the expression of exogenous genes via an ecdysone receptor complex |
US7456315B2 (en) | 2003-02-28 | 2008-11-25 | Intrexon Corporation | Bioavailable diacylhydrazine ligands for modulating the expression of exogenous genes via an ecdysone receptor complex |
CN1927831B (en) * | 2005-07-06 | 2011-02-09 | 南开大学 | N-sulfenate group diaromatic hydrazide derivative, preparation and application thereof |
US10633361B2 (en) | 2007-05-29 | 2020-04-28 | Intrexon Corporation | Chiral diacylhydrazine ligands for modulating the expression of exogenous genes via an ecdysone receptor complex |
US8884060B2 (en) | 2007-05-29 | 2014-11-11 | Intrexon Corporation | Process of preparing chiral diacylhydrazine ligands |
US9598355B2 (en) | 2007-05-29 | 2017-03-21 | Intrexon Corporation | Chiral diacylhydrazine ligands for modulating the expression of exogenous genes via an ecdysone receptor complex |
CN101891708A (en) * | 2009-06-26 | 2010-11-24 | 南开大学 | Diacylhydrazine compounds containing 4-methyl-1,2,3-thiadiazole groups, preparation method and application thereof |
US9512148B2 (en) | 2013-03-15 | 2016-12-06 | Intrexon Corporation | Boron-containing diacylhydrazines |
US9127024B2 (en) | 2013-03-15 | 2015-09-08 | Intrexon Corporation | Boron-containing diacylhydrazines |
US10464951B2 (en) | 2013-03-15 | 2019-11-05 | Intrexon Corporation | Boron-containing diacylhydrazines |
US10851119B2 (en) | 2013-03-15 | 2020-12-01 | Intrexon Corporation | Boron-containing diacylhydrazines |
WO2014144380A1 (en) * | 2013-03-15 | 2014-09-18 | Intrexon Corporation | Boron-containing diacylhydrazines |
US9944659B2 (en) | 2014-09-17 | 2018-04-17 | Intrexon Corporation | Boron-containing diacylhydrazine compounds |
US10570158B2 (en) | 2014-09-17 | 2020-02-25 | Intrexon Corporation | Boron-containing diacylhydrazine compounds |
Also Published As
Publication number | Publication date |
---|---|
HUT73160A (en) | 1996-06-28 |
KR960003575A (en) | 1996-02-23 |
HU9502200D0 (en) | 1995-09-28 |
KR100394165B1 (en) | 2003-10-22 |
IL114541A0 (en) | 1995-11-27 |
CN1119182A (en) | 1996-03-27 |
JPH0881433A (en) | 1996-03-26 |
TR199500888A2 (en) | 1996-10-21 |
EP0693486A1 (en) | 1996-01-24 |
CA2154411A1 (en) | 1996-01-23 |
BR9503404A (en) | 1996-02-27 |
AU690990B2 (en) | 1998-05-07 |
ZA956068B (en) | 1996-01-22 |
AU2490495A (en) | 1996-02-01 |
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