US3915212A - Flexible medical fluid container having a combined fill and administration port and reinforced hanger - Google Patents

Flexible medical fluid container having a combined fill and administration port and reinforced hanger Download PDF

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Publication number
US3915212A
US3915212A US423324A US42332473A US3915212A US 3915212 A US3915212 A US 3915212A US 423324 A US423324 A US 423324A US 42332473 A US42332473 A US 42332473A US 3915212 A US3915212 A US 3915212A
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Prior art keywords
container
port
cover
fill
administration
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US423324A
Inventor
Albert Frank Bujan
Harold Anthony Betka
Eugene Anthony Parker
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Abbott Laboratories
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Abbott Laboratories
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Priority to US423324A priority Critical patent/US3915212A/en
Priority to CA215,246A priority patent/CA1046462A/en
Priority to ZA00747751A priority patent/ZA747751B/en
Priority to DE19742458220 priority patent/DE2458220C3/en
Priority to GB53203/74A priority patent/GB1479045A/en
Priority to IT30305/74A priority patent/IT1026875B/en
Priority to JP49140603A priority patent/JPS6219868B2/ja
Priority to FR7440532A priority patent/FR2253496B1/fr
Priority to PH16608A priority patent/PH12068A/en
Priority to AU76232/74A priority patent/AU484504B2/en
Application granted granted Critical
Publication of US3915212A publication Critical patent/US3915212A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/05Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
    • A61J1/10Bag-type containers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14Details; Accessories therefor
    • A61J1/1406Septums, pierceable membranes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14Details; Accessories therefor
    • A61J1/1462Containers with provisions for hanging, e.g. integral adaptations of the container
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14Details; Accessories therefor
    • A61J1/1475Inlet or outlet ports
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S383/00Flexible bags
    • Y10S383/904Filling tube
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S383/00Flexible bags
    • Y10S383/906Dispensing feature

Definitions

  • Niblack [5 7 ABSTRACT A flexible container for medical fluids having a combined fill and administration port of at least two parts so that the container can be filled through the first part of the port, the second part thereafter being inserted into the first part to seal the container, and a reinforced hanger portion to prevent uneven collapse of the top of the container and thereby permit a well defined meniscus for improved readability of the fluid level within the container.
  • FLEXIBLE MEDICAL FLUID CONTAINER HAVING A COMBINED FILL AND ADMINISTRATION PORT AND REINFORCED HANGER BACKGROUND OF THE INVENTION Medical solutions for irrigating purposes or for intravenous administration are generally stored and administered from glass bottles. The bottles are filled, a special closure is attached, and the filled, sealed bottles are then sterilized.
  • the closures generally comprise a bung for sealing the mouth of the bottle, the bung including a puncturable diaphragm which can'subsequently be punctured for entry into the bottle.
  • an administration'set is attached to the bottle by removing the protective portion of the closure and puncturing the diaphragm in the closure with a piercing cannula.
  • the present invention comprises a flexible container having a fill and administration port of at least two separate parts so thatthe container can be filled through the first part of the port which is attached to the container, the second part thereafter inserted therein and sealed thereto to thereby seal the container.
  • the container also includes a reinforced hanger portion so that when the filled container is suspended from the hospital standard, a well defined meniscus will result for improved readability of the fluid level within the container.
  • the reinforcement preferably comprises a card encapsulated within the hanger portion of the container as well as a stiffening rib positioned along the hanger portion of the container transverse to the axis thereof.
  • FIG. 3 is a side elevational view of the container of FIG. 1, filled with fluid
  • FIG. 4 is a sectional view of the additive port of the container of FIG. 1 as viewed along the lines 4-4 of FIG. 1;
  • FIG. 5 is a sectional view of the combined fill and administration port of the container of FIG. 1;
  • FIG. 6 is an end elevational view of the container as viewed along the lines 6-6 of FIG. 1.
  • FIG. 1 illustrates a flexible, collapsible container 10 of the present invention suitable for medical fluids.
  • the container 10 includes a sealed flexible bag 11 made of a chemically inert, plastic material such as polyvinyl chloride.
  • the bag 11 includes a pair of opposed walls 12, 13 sealed along the perimeter 14 thereof to form the container 10.
  • At one end 15 of the bag 11 a reinforced hanger portion 16 is fabricated.
  • the reinforced hanger portion 16 includes a stiff reinforcing card 17 encapsulated within the envelope 18 formed by the two side walls 12, 13 when they are sealed together.
  • a flap 19 formed by sealing of the two sheets or extruded tube of plastic together and having an opening 20 therein for hanging of the bag in use. Reinforcing ribs 21, 22 are formed during the sealing process to provide extra stiffness to the hanger portion 17.
  • the stiff card 17 encapsulated within the hanger portion 16 of the container 10 provides reinforcement to the hanger portion 16 as well as containing label copy.
  • Flexible containers when suspended for use, tend to stretch and distort so that measurement of the fluid level within the container is difficult.
  • the reinforced hanger portion 16 acts to prevent distortion of the bag 1 1 and therefore provides a well defined meniscus for improvedreadability of the calibrations and fluid level.
  • the opening 20 in the flap 19 can have a variety of shapes.
  • one or more ports can be incorporated in the bag 11.
  • a fill and administration port 24 comprises a fill port 25 formed by a semi-rigid tubular portion 26 having open ends 27 and 28, the tubular portion 26 extending within the bag 11 to provide communication into the interior of the bag 11.
  • An annular flange 29 extends from the end 28 of the fill port 26.
  • the fill port 25 is sealed in place during fabrication of the bag 11.
  • the tubular portion 26 of the fill port 25 is positioned in place between two sheets of plastic forming the side walls 12, 13 of the bag 11. As the perimeter 14 of the opposed walls 12, 13 is sealed together, the fill port 25 will be sealed in place, the port 25 providing communication into the interior of the bag 11 for filling purposes.
  • the administration port 30 includes a tubular section 31 having a passageway 32 therethrough with an open end 33, the other end 34 of the passageway 32 being closed by a puncturable diaphragm 35. Extending from the open end 33 of the administration'port 30 is an annular flange 36 adapted to mate with the flange 29 of the fill port 25.
  • the administration port 30 is sealed by a cover 37 which comprises a body 38 having an annular flange 39 extending therefrom coextensive with the flange 29 of the fill port and the flange 36 of the administration port 30 and including a handle 40 extending perpendicularly away from the outer surface of said cover immediately opposite a weakening ring.
  • a weakening ring 41 is formed in the cover 37 radially inwardly of the cover flange to facilitate removal.
  • the fill port 25, administration port 30 and cover 37 are sealed together along the flanges 29, 36, 39 thereof after assembly. If the container is to be utilized for a fluid to which no additional medicament is to beadded, the fill and administration port 24 is sufficient and no other ports need be added.
  • the additive port 45 is positioned on one of the side walls l2, l3 and sealed thereto and comprises a tubular section 46 having an open end 47 and aclosed end 48 together with a passage 49 therethrough.
  • the closed end 48 is spaced away from the open end 47 and forms a puncturable diaphragm 50 to facilitate entry of a needle or cannula into the bag 11.
  • An integral cover 51 is positioned over the tubular section 46, the cover 51 comprising a tubular section 52 formed by the side walls 53 and an end wall 54, an annular flange 55 extending from the side wall.
  • the end wall 54 includes a thin portion 56 to facilitate opening of the cover 51.
  • a handle base 57 extends from the end wall 54 and includes a handle 58 extending therefrom.
  • the flange 55 of the coverSl is sealed directly to one of the bag 11 walls l2, 13 so that the wall 12, 13 closes off the passage and further, forms a puncturable membrane.
  • the puncturable diaphragm 50 of the additive port 45 is spaced away from the open end 47, the port 45 allows piercing with a long hypodermic needle and minimizes the possibility of piercing the opposite wall of the container 10. Additionally, once sterilized, the cover 51 will maintain sterility so that upon use, there is no need. to swab the puncturable diaphragm 50 with a bactericide.
  • the container 10 can be fabricated to form a bag 11 from two sheets of plastic sealed together preferably by heat sealing methods. Prior to sealing the perimeter 14 of theopposed walls 12, 13 to form the bag 11, the tubular portion 26 of the fill port is positioned between the two sheets of plastic and sealed in place as previously described. Any excess plastic is trimmed from the sides of the container 11 and, if the container 11 is intended for use with intravenous fluid or other fluid which may require the addition of medicament thereto, an administration port is sealed to the side wall l2, 13 of the container 10. The appropriate fluid is then added to the container 10 through the fill port 25 and the administration port 30 is thereafter inserted and sealed in place.
  • the cover 37 of the administration port 30 is removed and the piercing cannula of an administration set is inserted therein, piercing the diaphragm and thereby providing communication with the inside of the bag 11 so that fluid can flow from the container 10 through the tubing of the administration set (not shown) tothe patient.
  • the container 10 will collapse due to atmospheric pressure. Accordingly, no air vent is required, thereby minimizing the possibility of contamination.
  • the reinforced hanger portion 16 and particularly the card 17 which is encapsulated therein will prevent the container 10 from distorting so that the meniscus formed by the fluid can be easily read and the amount of fluid being administered to the patient can be easily and accurately determined.
  • an additive port 45 can be affixed to a side wall l2, 13 of the flexible bag 11. If the addition of a medicament to the fluid within the container 10 is necessary, the cover 51 of the additive port 55 can be opened by grasping the handle 58 and applying pressure thereby causing the thin portion 56 of the cover 51 to fracture to expose the diaphragm 50. As illustrated in FIG. 4, the needle of a syringe or additive vial can then be inserted through the puncturable diaphragm 50 and the medicament within the syringe or vial emptied into the bag 11.
  • a reinforced hanger portion at one end of said container including a stiff card encapsulated within an envelope formed by said sealed opposed walls, said reinforced hanger portion minimizing distortion of said container so that the meniscus formed by said fluid therein can be easily read and the amount of fluid being administered can be accurately determined, combined fill and administration port disposed on the end of said container opposite said hanger portion and including a fill port formed by a semi-rigid tubular portion having open ends, said tubular portion being disposed between said opposed walls of said container and sealed therein to provide communication into the interior of said container, and an annular flange perpendicular to the axis of said tubular portion and extending from the end of said tubular portion spaced away from said container,
  • said administration port including a close fitting tubular section inserted into said tubular portion of said fill port and having a passageway therethrough with an open end spaced away from said container, the other end of said passageway being closed by a puncturable diaphragm, the end of said tubular section of said administration port spaced away from said container having an annular flange also perpendicular to the axis of said tubular portion and said tubular section and extending therefrom, said flange of said tubular section being coextensive with said flange of said fill port; and
  • a cover for sealing said combined fill and administration port said cover including a body having an annular flange extending therefrom coextensive with said flanges of said fill and administration ports, the respective flanges of said fill port, administration port and cover being sealed together to seal said container, said cover including a weakening ring formed in the inner surface of said cover radially inwardly of said cover flange and adjacent said administration port, and an integral handle extending perpendicularly away from the outer surface of said cover immediately opposite said weakening ring, which handle and weakening ring facilitate removal of said cover.
  • the flexible, collapsible container of claim 1 including reinforcing ribs formed in the reinforced hanger portion and arranged transverse to the longitu- 'dinal axis of the container.

Abstract

A flexible container for medical fluids having a combined fill and administration port of at least two parts so that the container can be filled through the first part of the port, the second part thereafter being inserted into the first part to seal the container, and a reinforced hanger portion to prevent uneven collapse of the top of the container and thereby permit a well defined meniscus for improved readability of the fluid level within the container.

Description

United States Patent Bujan et al.
[4 1 Oct. 28, 1975 FLEXIBLE MEDICAL FLUID CONTAINER HAVING A COMBINED FILL AND ADMINISTRATION PORT AND REINFORCED HANGER Inventors: Albert Frank Bujan; Harold Anthony Betka, both of Waukegan; Eugene Anthony Parker, Lindenhurst, all of I11.
Abbott Laboratories, North Chicago, Ill.
Filed: Dec. 10, 1973 Appl. N0.: 423,324
Assignee:
US. Cl. 150/8; 215/258; 128/214 D Int. Cl. B65D 33/016; B65D 41/058 Field of Search 150/8, DIG. 1, 9; 206/804, 206/69; 128/272, 274, 214 D, DIG. 24, DIG. 26; 215/232, 258, 298, 349
References Cited UNITED STATES PATENTS 11/1954 Ryan 128/272 3,171,412 3/1965 Braun 128/214 D 3,215,299 11/1965 Coanda 150/12 3,330,281 7/1967 Visser 128/272 3,331,421 7/1967 Lambert 150/9 3,394,831 7/1968 Bathish 128/272 3,415,299 12/1968 l-linman 150/1 3,661,153 5/1972 Polk 150/8 3,810,503 5/1974 Lewis 150/8 Primary ExaminerWilliam 1. Price Attorney, Agent, or Firm-Aaron L. I-lardt; Robert L. Niblack [5 7 ABSTRACT A flexible container for medical fluids having a combined fill and administration port of at least two parts so that the container can be filled through the first part of the port, the second part thereafter being inserted into the first part to seal the container, and a reinforced hanger portion to prevent uneven collapse of the top of the container and thereby permit a well defined meniscus for improved readability of the fluid level within the container.
2 Claims, 6 Drawing Figures U.S. Patent Oct. 28, 1975 FIG.6
FLEXIBLE MEDICAL FLUID CONTAINER HAVING A COMBINED FILL AND ADMINISTRATION PORT AND REINFORCED HANGER BACKGROUND OF THE INVENTION Medical solutions for irrigating purposes or for intravenous administration are generally stored and administered from glass bottles. The bottles are filled, a special closure is attached, and the filled, sealed bottles are then sterilized. The closures generally comprise a bung for sealing the mouth of the bottle, the bung including a puncturable diaphragm which can'subsequently be punctured for entry into the bottle. At the point of use, an administration'set is attached to the bottle by removing the protective portion of the closure and puncturing the diaphragm in the closure with a piercing cannula. Communication to the fluid inside the bottle is thereby achieved and the fluid is subsequently administered to the patient through tubing attached to the cannula. To permit the fluid to flow from the bottle, air must be permitted to enter therein which can be achieved through an air filter incorporated in the cannula or by an air entry port in the closure. Potentially, contamination of the fluid within the bottle can result through the air filter or air entry port and consequently it is desirable to administer such fluids from plastic containers such as described and illustrated in U.S. Pat. Nos. 2,693,189 issued Nov. 2, 1954 or 3,509,879 issued May 5, 1970. During administration of the fluid, such flexible containers will collapse due to atmospheric pressure and hence it is not necessary to admit air within the container. Consequently, a potential source of contamination can be eliminated or minimized. However, such flexible containers are difficult to fill and seal and when hung on a hospital hanger for administratiombecause of their flexible nature causing distortion, it is difficult to read the meniscus which is necessary in order to determine the amount of fluid being administered to the patient.
SUMMARY OF THE INVENTION The present invention comprises a flexible container having a fill and administration port of at least two separate parts so thatthe container can be filled through the first part of the port which is attached to the container, the second part thereafter inserted therein and sealed thereto to thereby seal the container. The container also includes a reinforced hanger portion so that when the filled container is suspended from the hospital standard, a well defined meniscus will result for improved readability of the fluid level within the container. The reinforcement preferably comprises a card encapsulated within the hanger portion of the container as well as a stiffening rib positioned along the hanger portion of the container transverse to the axis thereof.
BRIEF DESCRIPTION OF DRAWINGS card which is encapsulated into the hanger portion of the container;
FIG. 3 is a side elevational view of the container of FIG. 1, filled with fluid;
FIG. 4 is a sectional view of the additive port of the container of FIG. 1 as viewed along the lines 4-4 of FIG. 1;
FIG. 5 is a sectional view of the combined fill and administration port of the container of FIG. 1; and
FIG. 6 is an end elevational view of the container as viewed along the lines 6-6 of FIG. 1.
DETAILED DESCRIPTION Referring to the drawings, FIG. 1 illustrates a flexible, collapsible container 10 of the present invention suitable for medical fluids. The container 10 includes a sealed flexible bag 11 made of a chemically inert, plastic material such as polyvinyl chloride. The bag 11 includes a pair of opposed walls 12, 13 sealed along the perimeter 14 thereof to form the container 10. At one end 15 of the bag 11 a reinforced hanger portion 16 is fabricated. The reinforced hanger portion 16 includes a stiff reinforcing card 17 encapsulated within the envelope 18 formed by the two side walls 12, 13 when they are sealed together. Extending from the envelope 18 is a flap 19 formed by sealing of the two sheets or extruded tube of plastic together and having an opening 20 therein for hanging of the bag in use. Reinforcing ribs 21, 22 are formed during the sealing process to provide extra stiffness to the hanger portion 17. The stiff card 17 encapsulated within the hanger portion 16 of the container 10 provides reinforcement to the hanger portion 16 as well as containing label copy. Flexible containers when suspended for use, tend to stretch and distort so that measurement of the fluid level within the container is difficult. When the container 10 is suspended from a hospital standard, the reinforced hanger portion 16 acts to prevent distortion of the bag 1 1 and therefore provides a well defined meniscus for improvedreadability of the calibrations and fluid level. Of course, the opening 20 in the flap 19 can have a variety of shapes.
Depending on the end use intended for the container 10, whetherfor irrigating fluids or intravenous fluids, one or more ports can be incorporated in the bag 11. As illustrated, on the end 23 of the bag 11 opposite the hanger portion 19 are positioned two ports, a fill and administration port 24 and an additive port 45. The fill and administration port 24 comprises a fill port 25 formed by a semi-rigid tubular portion 26 having open ends 27 and 28, the tubular portion 26 extending within the bag 11 to provide communication into the interior of the bag 11. An annular flange 29 extends from the end 28 of the fill port 26. The fill port 25 is sealed in place during fabrication of the bag 11. The tubular portion 26 of the fill port 25 is positioned in place between two sheets of plastic forming the side walls 12, 13 of the bag 11. As the perimeter 14 of the opposed walls 12, 13 is sealed together, the fill port 25 will be sealed in place, the port 25 providing communication into the interior of the bag 11 for filling purposes.
After the bag 11 is filled through the fill port 25, an administration port 30 is inserted into the fill port 25 and sealed thereto. The administration port 30 includes a tubular section 31 having a passageway 32 therethrough with an open end 33, the other end 34 of the passageway 32 being closed by a puncturable diaphragm 35. Extending from the open end 33 of the administration'port 30 is an annular flange 36 adapted to mate with the flange 29 of the fill port 25. The administration port 30 is sealed by a cover 37 which comprises a body 38 having an annular flange 39 extending therefrom coextensive with the flange 29 of the fill port and the flange 36 of the administration port 30 and including a handle 40 extending perpendicularly away from the outer surface of said cover immediately opposite a weakening ring. A weakening ring 41 is formed in the cover 37 radially inwardly of the cover flange to facilitate removal. The fill port 25, administration port 30 and cover 37 are sealed together along the flanges 29, 36, 39 thereof after assembly. If the container is to be utilized for a fluid to which no additional medicament is to beadded, the fill and administration port 24 is sufficient and no other ports need be added.
The additive port 45 is positioned on one of the side walls l2, l3 and sealed thereto and comprises a tubular section 46 having an open end 47 and aclosed end 48 together with a passage 49 therethrough. The closed end 48 is spaced away from the open end 47 and forms a puncturable diaphragm 50 to facilitate entry of a needle or cannula into the bag 11. An integral cover 51 is positioned over the tubular section 46, the cover 51 comprising a tubular section 52 formed by the side walls 53 and an end wall 54, an annular flange 55 extending from the side wall. The end wall 54 includes a thin portion 56 to facilitate opening of the cover 51. A handle base 57 extends from the end wall 54 and includes a handle 58 extending therefrom. The flange 55 of the coverSl is sealed directly to one of the bag 11 walls l2, 13 so that the wall 12, 13 closes off the passage and further, forms a puncturable membrane. As is apparent, since the puncturable diaphragm 50 of the additive port 45 is spaced away from the open end 47, the port 45 allows piercing with a long hypodermic needle and minimizes the possibility of piercing the opposite wall of the container 10. Additionally, once sterilized, the cover 51 will maintain sterility so that upon use, there is no need. to swab the puncturable diaphragm 50 with a bactericide.
.The container 10 can be fabricated to form a bag 11 from two sheets of plastic sealed together preferably by heat sealing methods. Prior to sealing the perimeter 14 of theopposed walls 12, 13 to form the bag 11, the tubular portion 26 of the fill port is positioned between the two sheets of plastic and sealed in place as previously described. Any excess plastic is trimmed from the sides of the container 11 and, if the container 11 is intended for use with intravenous fluid or other fluid which may require the addition of medicament thereto, an administration port is sealed to the side wall l2, 13 of the container 10. The appropriate fluid is then added to the container 10 through the fill port 25 and the administration port 30 is thereafter inserted and sealed in place.
In use, the cover 37 of the administration port 30 is removed and the piercing cannula of an administration set is inserted therein, piercing the diaphragm and thereby providing communication with the inside of the bag 11 so that fluid can flow from the container 10 through the tubing of the administration set (not shown) tothe patient. As the fluid is administered, the container 10 will collapse due to atmospheric pressure. Accordingly, no air vent is required, thereby minimizing the possibility of contamination. Likewise, the reinforced hanger portion 16 and particularly the card 17 which is encapsulated therein will prevent the container 10 from distorting so that the meniscus formed by the fluid can be easily read and the amount of fluid being administered to the patient can be easily and accurately determined.
As previously described, if the container 10 is to be used for the storage and administration of intravenous fluids to which it may be necessary to add additional medicament, an additive port 45 can be affixed to a side wall l2, 13 of the flexible bag 11. If the addition of a medicament to the fluid within the container 10 is necessary, the cover 51 of the additive port 55 can be opened by grasping the handle 58 and applying pressure thereby causing the thin portion 56 of the cover 51 to fracture to expose the diaphragm 50. As illustrated in FIG. 4, the needle of a syringe or additive vial can then be inserted through the puncturable diaphragm 50 and the medicament within the syringe or vial emptied into the bag 11.
What is claimed is:
l. A flexible, collapsible container for medical fluids made of a chemically inert plastic material, said container comprising:
a pair of opposed walls sealed along the entire perimeter thereof to form said container,
a reinforced hanger portion at one end of said container including a stiff card encapsulated within an envelope formed by said sealed opposed walls, said reinforced hanger portion minimizing distortion of said container so that the meniscus formed by said fluid therein can be easily read and the amount of fluid being administered can be accurately determined, combined fill and administration port disposed on the end of said container opposite said hanger portion and including a fill port formed by a semi-rigid tubular portion having open ends, said tubular portion being disposed between said opposed walls of said container and sealed therein to provide communication into the interior of said container, and an annular flange perpendicular to the axis of said tubular portion and extending from the end of said tubular portion spaced away from said container,
said administration port including a close fitting tubular section inserted into said tubular portion of said fill port and having a passageway therethrough with an open end spaced away from said container, the other end of said passageway being closed by a puncturable diaphragm, the end of said tubular section of said administration port spaced away from said container having an annular flange also perpendicular to the axis of said tubular portion and said tubular section and extending therefrom, said flange of said tubular section being coextensive with said flange of said fill port; and
a cover for sealing said combined fill and administration port, said cover including a body having an annular flange extending therefrom coextensive with said flanges of said fill and administration ports, the respective flanges of said fill port, administration port and cover being sealed together to seal said container, said cover including a weakening ring formed in the inner surface of said cover radially inwardly of said cover flange and adjacent said administration port, and an integral handle extending perpendicularly away from the outer surface of said cover immediately opposite said weakening ring, which handle and weakening ring facilitate removal of said cover.
2. The flexible, collapsible container of claim 1 including reinforcing ribs formed in the reinforced hanger portion and arranged transverse to the longitu- 'dinal axis of the container.

Claims (2)

1. A flexible, collapsible container for medical fluids made of a chemically inert plastic material, said container comprising: a pair of opposed walls sealed along the entire perimeter thereof to form said container, a reinforced hanger portion at one end of said container including a stiff card encapsulated within an envelope formed by said sealed opposed walls, said reinforced hanger portion minimizing distortion of said container so that the meniscus formed by said fluid therein can be easily read and the amount of fluid being administered can be accurately determined, a combined fill and administration port disposed on the end of said container opposite said hanger portion and including a fill port formed by a semi-rigid tubular portion having open ends, said tubular portion being disposed between said opposed walls of said container and sealed therein to provide communication into the interior of said container, and an annular flange perpendicular to the axis of said tubular portion and extending from the end of said tubular portion spaced away from said container, said administration port including a close fitting tubular section inserted into said tubular portion of said fill port and having a passageway therethrough with an open end spaced away from said container, the other end of said passageway being closed by a puncturable diaphragm, the end of said tubular section of said administration port spaced away from said container having an annular flange also perpendicular to the axis of said tubular portion and said tubular section and extending therefrom, said flange of said tubular section being coextensive with said flange of said fill port; and a cover for sealing said combined fill and administration port, said cover including a body having an annular flange extending therefrom coextensive with said flanges of said fill and administration ports, the respective flanges of said fill port, administration port and cover being sealed together to seal said container, said cover including a weakening ring formed in the inner surface of said cover radially inwardly of said cover flange and adjacent said administration port, and an integral handle extending perpendicularly away from the outer surface of said cover immediately opposite said weakening ring, which handle and weakening ring facilitate removal of said cover.
2. The flexible, collapsible container of claim 1 including reinforcing ribs formed in the reinforced hanger portion and arranged transverse to the longitudinal axis of the container.
US423324A 1973-12-10 1973-12-10 Flexible medical fluid container having a combined fill and administration port and reinforced hanger Expired - Lifetime US3915212A (en)

Priority Applications (10)

Application Number Priority Date Filing Date Title
US423324A US3915212A (en) 1973-12-10 1973-12-10 Flexible medical fluid container having a combined fill and administration port and reinforced hanger
CA215,246A CA1046462A (en) 1973-12-10 1974-12-04 Flexible medical fluid container having a combined fill and administration port and reinforced hanger
ZA00747751A ZA747751B (en) 1973-12-10 1974-12-05 A flexible medical fluid container having a combined fill and administration port and reinforced hanger
GB53203/74A GB1479045A (en) 1973-12-10 1974-12-09 Flexible medical fluid container having a combined filler and administration port and reinforced hanger
DE19742458220 DE2458220C3 (en) 1973-12-10 1974-12-09 Flexible, collapsible container made of chemically neutral plastic for medical fluids
IT30305/74A IT1026875B (en) 1973-12-10 1974-12-09 FLEXIBLE CONTAINER FOR MEDICAL FLUIDS FITTED WITH A COMBINED FILLING AND STRETCHING LIGHT AND A REINFORCED SUSPENDING PART
JP49140603A JPS6219868B2 (en) 1973-12-10 1974-12-09
FR7440532A FR2253496B1 (en) 1973-12-10 1974-12-10
PH16608A PH12068A (en) 1973-12-10 1974-12-10 A flexible medical fluid container having a combine fill and administration port and reinforced hanger
AU76232/74A AU484504B2 (en) 1973-12-10 1974-12-10 A flexible medical fluid container having a combined fill and administration portand reinforced hanger

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US423324A US3915212A (en) 1973-12-10 1973-12-10 Flexible medical fluid container having a combined fill and administration port and reinforced hanger

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US3915212A true US3915212A (en) 1975-10-28

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JP (1) JPS6219868B2 (en)
CA (1) CA1046462A (en)
FR (1) FR2253496B1 (en)
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USD243121S (en) * 1975-03-17 1977-01-18 Baxter Travenol Laboratories, Inc. Medical solution bag
US4023607A (en) * 1974-06-07 1977-05-17 Automaticon A/S Polyethylene urine bag with tube
US4049033A (en) * 1974-11-21 1977-09-20 Baxter Travenol Laboratories, Inc. Molded collapsible solution container
US4112989A (en) * 1975-11-06 1978-09-12 Baxter Travenol Laboratories, Inc. Flexible collapsible blood freezing containers
US4119267A (en) * 1976-08-18 1978-10-10 Agis Frank Kydonieus Blood and intravenous solution bag
US4119128A (en) * 1977-02-18 1978-10-10 Marilyn Bishop Tamperproof sterile port cover and method of making same
US4126167A (en) * 1976-12-06 1978-11-21 Patient Care Products, Inc. Gastric tube drainage bag
US4144673A (en) * 1977-08-29 1979-03-20 Quast Danny H System and method for introducing systemic treatment liquids into trees and similar plants
US4175994A (en) * 1977-11-17 1979-11-27 Baxter Travenol Laboratories, Inc. Method of manufacturing a flexible collapsible container with a stiffening member
US4187893A (en) * 1978-07-19 1980-02-12 Abbott Laboratories Combined additive and administration port for a container
US4199062A (en) * 1978-04-13 1980-04-22 Baxter Travenol Laboratories, Inc. Liquid container with hang flap
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US4305443A (en) * 1979-03-05 1981-12-15 Baxter Travenol Laboratories, Inc. Seal for flexible container having flexible, generally conical portions
US4335770A (en) * 1980-10-08 1982-06-22 Baxter Travenol Laboratories, Inc. Enteral feeding container
US4344472A (en) * 1981-04-13 1982-08-17 Abbott Laboratories Pull tab tear cap for container port
US4362158A (en) * 1980-01-22 1982-12-07 Paolo Lena Synthetic bag-type container for human blood and its fractions, perfusion solutions, dialysis solutions and alimentary and chemical liquids in general
WO1982004398A1 (en) * 1981-06-12 1982-12-23 Niklasson Tage Arrangement for bags especially for infusion and procedure for their production
US4368765A (en) * 1980-12-12 1983-01-18 Abbott Laboratories Flexible bag with recessed scrapless hanger
US4415393A (en) * 1981-10-22 1983-11-15 Baxter Travenol Laboratories, Inc. Method of making a frangible port protector
US4441538A (en) * 1979-12-26 1984-04-10 Abbott Laboratories Flexible container with integral ports and diaphragm
US4523691A (en) * 1983-04-08 1985-06-18 Abbott Laboratories Port structure for I.V. container
US4547900A (en) * 1979-12-26 1985-10-15 Abbott Laboratories Flexible container with integral ports and diaphragm
USRE32065E (en) * 1974-11-21 1986-01-14 Baxter Travenol Laboratories, Inc. Molded collapsible solution container
US4601704A (en) * 1983-10-27 1986-07-22 Abbott Laboratories Container mixing system with externally mounted drug container
US4606734A (en) * 1984-02-22 1986-08-19 Abbott Laboratories Container mixing system with externally mounted drug container
US4614267A (en) * 1983-02-28 1986-09-30 Abbott Laboratories Dual compartmented container
US4614515A (en) * 1984-03-19 1986-09-30 Abbott Laboratories Drug delivery system
US4632673A (en) * 1983-06-15 1986-12-30 Hantaaki Oy Pierceable port for containers
US4636204A (en) * 1982-04-13 1987-01-13 Gambro Lundia Ab Coupling for the connection of flexible tubes and the like
US4722727A (en) * 1984-07-18 1988-02-02 Abbott Laboratories Flexible container
US4757911A (en) * 1985-12-09 1988-07-19 Abbott Laboratories Container and closure construction
US4781679A (en) * 1986-06-12 1988-11-01 Abbott Laboratories Container system with integral second substance storing and dispensing means
US4786279A (en) * 1986-07-31 1988-11-22 Abbott Laboratories Container for mixture of materials
US4790841A (en) * 1981-03-31 1988-12-13 Gislaved Plastindustri Ab Device for bag-shaped liquid-containers for sick-care
US4795270A (en) * 1987-02-02 1989-01-03 Heyden Eugene L Reclosable bag with a folded portion engaged by a unitary material separation arrangement
WO1992019284A1 (en) * 1991-05-08 1992-11-12 Baxter International Inc. Container for irradiation of blood products
US5196001A (en) * 1991-03-05 1993-03-23 Ti Kao Devices and methods for preparing pharmaceutical solutions
US5343903A (en) * 1991-06-03 1994-09-06 Winder D Howard Method of transferring a liquid to a reservoir using a storage bag having a passage therethrough
US5364385A (en) * 1990-05-09 1994-11-15 Lifesource Advanced Blood Bank Systems, Inc. Storage bag for blood and blood components
US5391163A (en) * 1992-01-31 1995-02-21 Inpaco Corporation Pouch for administering medical fluids
USD388168S (en) * 1996-05-13 1997-12-23 Mcgaw, Inc. Flexible multiple compartment medical container
US5971972A (en) * 1996-06-27 1999-10-26 Rosenbaum; Jay D. Failsafe intravenous transfusion system for typed blood
US6183460B1 (en) * 1998-01-22 2001-02-06 Baxter International Inc. Multi-use solution container having flaps
US6267564B1 (en) 1999-05-12 2001-07-31 Sims Deltec, Inc. Medical reservoir bag and system
WO2001087223A1 (en) 2000-05-03 2001-11-22 Romano Jack W Material(s)/content(s) management method and apparatus
US20030053931A1 (en) * 2000-02-18 2003-03-20 Selective Micro Technologies, Llc Apparatus and method for controlled delivery of a gas
US20030075469A1 (en) * 1999-12-08 2003-04-24 Reinhold Herbert Withdrawal and injection system for medical solutions and a container with said withdrawal and injection system
US6602466B2 (en) 2000-02-18 2003-08-05 Selective Micro Technologies, Llc Apparatus and method for controlled delivery of a gas
US20030233083A1 (en) * 2002-06-12 2003-12-18 Vincent Houwaert Port, a container and a method for accessing a port
US20040001655A1 (en) * 2002-07-01 2004-01-01 Proicou George C. Drug containment system
US20040022676A1 (en) * 2000-02-18 2004-02-05 Selective Micro Technologies, Llc Apparatus and method for controlled delivery of a gas
US7066914B2 (en) 2000-07-12 2006-06-27 Bird Products Corporation Catheter having a tip with an elongated collar
US20090030396A1 (en) * 2007-07-26 2009-01-29 Rick George Ferris Infusion Bag with Needleless Access Port
US20100004618A1 (en) * 2008-07-03 2010-01-07 BAXTER INTERNATIONAL INC. and BAXTER HEALTHCARE S.A., WALLISELLEN Port assembly for use with needleless connector
US20100049160A1 (en) * 2008-08-19 2010-02-25 Baxter Healthcare S.A. Port assembly for use with needleless connector
US20100217179A1 (en) * 2009-02-20 2010-08-26 Baxter International Inc. Bulk delivery peritoneal dialysis system and method
US7976518B2 (en) 2005-01-13 2011-07-12 Corpak Medsystems, Inc. Tubing assembly and signal generator placement control device and method for use with catheter guidance systems
WO2011151492A1 (en) * 2010-05-31 2011-12-08 Onedose Pharma, S.L. Envelope for single drug dose
US8172823B2 (en) 2008-07-03 2012-05-08 Baxter International Inc. Port assembly for use with needleless connector
US20120145580A1 (en) * 2009-08-24 2012-06-14 Lfb Biomedicaments Bag for storing a therapeutic solution
CN102499887A (en) * 2011-10-28 2012-06-20 湖南千山制药机械股份有限公司 Transfusion soft bag
US8394080B2 (en) 2009-05-14 2013-03-12 Baxter International Inc. Needleless connector with slider
US20130192597A1 (en) * 2009-01-16 2013-08-01 Westmed, Inc. Reservoir System for Gas Delivery to a Patient
US20130269827A1 (en) * 2012-04-10 2013-10-17 John Sheridan Thomas, JR. Two compartment syringe accessible package and method of using and making the same
US9028441B2 (en) 2011-09-08 2015-05-12 Corpak Medsystems, Inc. Apparatus and method used with guidance system for feeding and suctioning
US20180192594A1 (en) * 2015-07-08 2018-07-12 Christophe De Mil Liquid-dispensing device
US20180346219A1 (en) * 2015-09-21 2018-12-06 Scholle Ipn Ip B.V. A Spouted Pouch Adapted To Be Filled With A Flowable Product And Method Of Production Thereof
US11905060B2 (en) * 2014-10-23 2024-02-20 Grifols, S.A. Method for the aseptic filling of a bag

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Cited By (94)

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US4023607A (en) * 1974-06-07 1977-05-17 Automaticon A/S Polyethylene urine bag with tube
USRE32065E (en) * 1974-11-21 1986-01-14 Baxter Travenol Laboratories, Inc. Molded collapsible solution container
US4049033A (en) * 1974-11-21 1977-09-20 Baxter Travenol Laboratories, Inc. Molded collapsible solution container
USD243121S (en) * 1975-03-17 1977-01-18 Baxter Travenol Laboratories, Inc. Medical solution bag
US4112989A (en) * 1975-11-06 1978-09-12 Baxter Travenol Laboratories, Inc. Flexible collapsible blood freezing containers
US4119267A (en) * 1976-08-18 1978-10-10 Agis Frank Kydonieus Blood and intravenous solution bag
US4126167A (en) * 1976-12-06 1978-11-21 Patient Care Products, Inc. Gastric tube drainage bag
US4119128A (en) * 1977-02-18 1978-10-10 Marilyn Bishop Tamperproof sterile port cover and method of making same
US4144673A (en) * 1977-08-29 1979-03-20 Quast Danny H System and method for introducing systemic treatment liquids into trees and similar plants
US4175994A (en) * 1977-11-17 1979-11-27 Baxter Travenol Laboratories, Inc. Method of manufacturing a flexible collapsible container with a stiffening member
US4278198A (en) * 1977-11-17 1981-07-14 Baxter Travenol Laboratories, Inc. Flexible collapsible container with a stiffening member
US4201208A (en) * 1977-11-30 1980-05-06 Abbott Laboratories Sterile connecting device
US4199062A (en) * 1978-04-13 1980-04-22 Baxter Travenol Laboratories, Inc. Liquid container with hang flap
US4187893A (en) * 1978-07-19 1980-02-12 Abbott Laboratories Combined additive and administration port for a container
US4305443A (en) * 1979-03-05 1981-12-15 Baxter Travenol Laboratories, Inc. Seal for flexible container having flexible, generally conical portions
US4244409A (en) * 1979-10-09 1981-01-13 Abbott Laboratories Collapsible solution container
US4441538A (en) * 1979-12-26 1984-04-10 Abbott Laboratories Flexible container with integral ports and diaphragm
US4547900A (en) * 1979-12-26 1985-10-15 Abbott Laboratories Flexible container with integral ports and diaphragm
US4362158A (en) * 1980-01-22 1982-12-07 Paolo Lena Synthetic bag-type container for human blood and its fractions, perfusion solutions, dialysis solutions and alimentary and chemical liquids in general
US4335770A (en) * 1980-10-08 1982-06-22 Baxter Travenol Laboratories, Inc. Enteral feeding container
US4368765A (en) * 1980-12-12 1983-01-18 Abbott Laboratories Flexible bag with recessed scrapless hanger
US4790841A (en) * 1981-03-31 1988-12-13 Gislaved Plastindustri Ab Device for bag-shaped liquid-containers for sick-care
US4344472A (en) * 1981-04-13 1982-08-17 Abbott Laboratories Pull tab tear cap for container port
WO1982004398A1 (en) * 1981-06-12 1982-12-23 Niklasson Tage Arrangement for bags especially for infusion and procedure for their production
US4415393A (en) * 1981-10-22 1983-11-15 Baxter Travenol Laboratories, Inc. Method of making a frangible port protector
US4636204A (en) * 1982-04-13 1987-01-13 Gambro Lundia Ab Coupling for the connection of flexible tubes and the like
US4614267A (en) * 1983-02-28 1986-09-30 Abbott Laboratories Dual compartmented container
US4523691A (en) * 1983-04-08 1985-06-18 Abbott Laboratories Port structure for I.V. container
US4632673A (en) * 1983-06-15 1986-12-30 Hantaaki Oy Pierceable port for containers
US4601704A (en) * 1983-10-27 1986-07-22 Abbott Laboratories Container mixing system with externally mounted drug container
US4606734A (en) * 1984-02-22 1986-08-19 Abbott Laboratories Container mixing system with externally mounted drug container
US4614515A (en) * 1984-03-19 1986-09-30 Abbott Laboratories Drug delivery system
US4722727A (en) * 1984-07-18 1988-02-02 Abbott Laboratories Flexible container
US4757911A (en) * 1985-12-09 1988-07-19 Abbott Laboratories Container and closure construction
US4781679A (en) * 1986-06-12 1988-11-01 Abbott Laboratories Container system with integral second substance storing and dispensing means
US4786279A (en) * 1986-07-31 1988-11-22 Abbott Laboratories Container for mixture of materials
US4795270A (en) * 1987-02-02 1989-01-03 Heyden Eugene L Reclosable bag with a folded portion engaged by a unitary material separation arrangement
US5364385A (en) * 1990-05-09 1994-11-15 Lifesource Advanced Blood Bank Systems, Inc. Storage bag for blood and blood components
US5196001A (en) * 1991-03-05 1993-03-23 Ti Kao Devices and methods for preparing pharmaceutical solutions
WO1992019284A1 (en) * 1991-05-08 1992-11-12 Baxter International Inc. Container for irradiation of blood products
US6245570B1 (en) 1991-05-08 2001-06-12 Baxter International Inc. Container for irradiation of blood products
US6696023B2 (en) 1991-05-08 2004-02-24 Baxter International Inc. Apparatus for irradiation of blood products
US20040172007A1 (en) * 1991-05-08 2004-09-02 Grimm Daniel J. Container for irradiation of blood products
US5343903A (en) * 1991-06-03 1994-09-06 Winder D Howard Method of transferring a liquid to a reservoir using a storage bag having a passage therethrough
US5391163A (en) * 1992-01-31 1995-02-21 Inpaco Corporation Pouch for administering medical fluids
USD388168S (en) * 1996-05-13 1997-12-23 Mcgaw, Inc. Flexible multiple compartment medical container
US5971972A (en) * 1996-06-27 1999-10-26 Rosenbaum; Jay D. Failsafe intravenous transfusion system for typed blood
US6183460B1 (en) * 1998-01-22 2001-02-06 Baxter International Inc. Multi-use solution container having flaps
US6267564B1 (en) 1999-05-12 2001-07-31 Sims Deltec, Inc. Medical reservoir bag and system
US20030075469A1 (en) * 1999-12-08 2003-04-24 Reinhold Herbert Withdrawal and injection system for medical solutions and a container with said withdrawal and injection system
US6602466B2 (en) 2000-02-18 2003-08-05 Selective Micro Technologies, Llc Apparatus and method for controlled delivery of a gas
US6607696B1 (en) 2000-02-18 2003-08-19 Selective Micro Technologies, Llc Apparatus and method for controlled delivery of a gas
US7922984B2 (en) 2000-02-18 2011-04-12 Selective Micro Technologies, Llc Apparatus and method for controlled delivery of a gas
US20040022676A1 (en) * 2000-02-18 2004-02-05 Selective Micro Technologies, Llc Apparatus and method for controlled delivery of a gas
US20030053931A1 (en) * 2000-02-18 2003-03-20 Selective Micro Technologies, Llc Apparatus and method for controlled delivery of a gas
WO2001087223A1 (en) 2000-05-03 2001-11-22 Romano Jack W Material(s)/content(s) management method and apparatus
US7066914B2 (en) 2000-07-12 2006-06-27 Bird Products Corporation Catheter having a tip with an elongated collar
US20030233083A1 (en) * 2002-06-12 2003-12-18 Vincent Houwaert Port, a container and a method for accessing a port
US6994699B2 (en) 2002-06-12 2006-02-07 Baxter International Inc. Port, a container and a method for accessing a port
US7025754B2 (en) * 2002-07-01 2006-04-11 Ventaira Pharmaceuticals, Inc. Drug containment system
WO2004002354A1 (en) * 2002-07-01 2004-01-08 Battellepharma, Inc. Drug containment system
US20040001655A1 (en) * 2002-07-01 2004-01-01 Proicou George C. Drug containment system
US10549074B2 (en) 2005-01-13 2020-02-04 Avent, Inc. Tubing assembly and signal generation placement device and method for use with catheter guidance systems
US9131956B2 (en) 2005-01-13 2015-09-15 Corpak Medsystems, Inc. Tubing assembly and signal generator placement control device and method for use with catheter guidance systems
US9579488B2 (en) 2005-01-13 2017-02-28 Corpak Medsystems, Inc. Tubing assembly and signal generator placement control device and method for use with catheter guidance systems
US9889277B2 (en) 2005-01-13 2018-02-13 Avent, Inc. Tubing assembly and signal generator placement control device and method for use with catheter guidance systems
US7976518B2 (en) 2005-01-13 2011-07-12 Corpak Medsystems, Inc. Tubing assembly and signal generator placement control device and method for use with catheter guidance systems
US20090030396A1 (en) * 2007-07-26 2009-01-29 Rick George Ferris Infusion Bag with Needleless Access Port
US8267912B2 (en) * 2007-07-26 2012-09-18 Richard George Ferris Infusion bag with needleless access port
US8172823B2 (en) 2008-07-03 2012-05-08 Baxter International Inc. Port assembly for use with needleless connector
US7905873B2 (en) 2008-07-03 2011-03-15 Baxter International Inc. Port assembly for use with needleless connector
US20100004618A1 (en) * 2008-07-03 2010-01-07 BAXTER INTERNATIONAL INC. and BAXTER HEALTHCARE S.A., WALLISELLEN Port assembly for use with needleless connector
US8062280B2 (en) 2008-08-19 2011-11-22 Baxter Healthcare S.A. Port assembly for use with needleless connector
US8486044B2 (en) 2008-08-19 2013-07-16 Baxter International Inc. Port assembly for use with needleless connector
US20100049160A1 (en) * 2008-08-19 2010-02-25 Baxter Healthcare S.A. Port assembly for use with needleless connector
US8936023B2 (en) * 2009-01-16 2015-01-20 Westmed, Inc. Reservoir system for gas delivery to a patient
US20130192597A1 (en) * 2009-01-16 2013-08-01 Westmed, Inc. Reservoir System for Gas Delivery to a Patient
US20100217179A1 (en) * 2009-02-20 2010-08-26 Baxter International Inc. Bulk delivery peritoneal dialysis system and method
US8394080B2 (en) 2009-05-14 2013-03-12 Baxter International Inc. Needleless connector with slider
US20120145580A1 (en) * 2009-08-24 2012-06-14 Lfb Biomedicaments Bag for storing a therapeutic solution
US10342734B2 (en) 2009-08-24 2019-07-09 Laboratoire Français Du Fractionnement Et Des Biotechnologies Bag for storing a therapeutic solution
US9468585B2 (en) * 2009-08-24 2016-10-18 Lfb Biomedicaments Bag for storing a therapeutic solution
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WO2011151492A1 (en) * 2010-05-31 2011-12-08 Onedose Pharma, S.L. Envelope for single drug dose
US9918907B2 (en) 2011-09-08 2018-03-20 Avent, Inc. Method for electromagnetic guidance of feeding and suctioning tube assembly
US9028441B2 (en) 2011-09-08 2015-05-12 Corpak Medsystems, Inc. Apparatus and method used with guidance system for feeding and suctioning
CN102499887B (en) * 2011-10-28 2014-07-09 湖南千山制药机械股份有限公司 Transfusion soft bag
CN102499887A (en) * 2011-10-28 2012-06-20 湖南千山制药机械股份有限公司 Transfusion soft bag
US20130269827A1 (en) * 2012-04-10 2013-10-17 John Sheridan Thomas, JR. Two compartment syringe accessible package and method of using and making the same
US11905060B2 (en) * 2014-10-23 2024-02-20 Grifols, S.A. Method for the aseptic filling of a bag
US20180192594A1 (en) * 2015-07-08 2018-07-12 Christophe De Mil Liquid-dispensing device
US10897854B2 (en) * 2015-07-08 2021-01-26 Christophe De Mil Slow rate liquid-dispensing device for arboriculture and viticulture
US20180346219A1 (en) * 2015-09-21 2018-12-06 Scholle Ipn Ip B.V. A Spouted Pouch Adapted To Be Filled With A Flowable Product And Method Of Production Thereof
US10829286B2 (en) * 2015-09-21 2020-11-10 Scholle Ipn Ip Bv Spouted pouch adapted to be filled with a flowable product and method of production thereof

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Publication number Publication date
DE2458220B2 (en) 1977-07-14
DE2458220A1 (en) 1975-06-12
IT1026875B (en) 1978-10-20
GB1479045A (en) 1977-07-06
FR2253496A1 (en) 1975-07-04
JPS50113090A (en) 1975-09-04
FR2253496B1 (en) 1980-04-18
PH12068A (en) 1978-10-30
ZA747751B (en) 1975-12-31
AU7623274A (en) 1976-06-10
CA1046462A (en) 1979-01-16
JPS6219868B2 (en) 1987-05-01

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