|Publication number||US3650831 A|
|Publication date||21 Mar 1972|
|Filing date||10 Mar 1969|
|Priority date||10 Mar 1969|
|Publication number||US 3650831 A, US 3650831A, US-A-3650831, US3650831 A, US3650831A|
|Inventors||Carlo Armando, Herrick Aaron B, Jungermann Eric|
|Original Assignee||Armour Dial Inc|
|Export Citation||BiBTeX, EndNote, RefMan|
|Patent Citations (9), Referenced by (111), Classifications (14)|
|External Links: USPTO, USPTO Assignment, Espacenet|
United States Patent Jungermann et al.
[451 Mar. 21, 1972  METHOD OF CLEANING SURFACES  Inventors: Eric Jungermann, Chicago; Aaron B. Herrick, La Grange; Armando Carlo, Chicago, all of ill.
 Assignee: Armour-Dial, Inc., Chicago, Ill.
 Filed: Mar. 10, 1969  Appl. No.: 805,797
 US. Cl ..134/27, 134/40, 252/156, 252/408  Int. Cl ..B08b 3/08  Field of Search 1 34/27, 28, 29, 22, 40; 252/408, 103, 156
 References Cited UNITED STATES PATENTS Phair ..252/408 X Sutton...
Primary Examiner-Joseph Scovronek Assistant ExaminerD. G. Millman Attorney-Carl C. Batz and Richard G. l-larrer  ABSTRACT A method of removing deposits of soil from surfaces, which comprises applying to said surfaces a caustic alkali including an acid-base color indicator, and applying an aqueous solution which is sufficiently acidic to substantially neutralize the caustic and visibly change the color of the caustic. The method has particular efficacy for the cleaning of the interior surfaces of ovens and similar surfaces.
5 Claims, No Drawings METHOD OF CLEANING SURFACES This invention relates to a method of cleaning deposits of soils from surfaces, for example, the interior surfaces of ovens and the like.
The cleaning of the interior surfaces of household cooking ovens is a difficult, tedious, and lengthy chore. A widely used oven cleaner is the spread-on, sodium hydroxide or potassium hydroxide formulations that are messy to apply and must be handled with care as the highly caustic material is capable of injuring the user. MOre recently, aerosol oven cleaners having a considerably lower concentration of alkali and containing a nonionic or ionic detergent with a solvent suchas water or alcohol have appeared. However, they are generally not as effective as the higher caustic content cleaners, although safer to use than the highly caustic formulas.
In accordance with the present invention a method is provided for removing deposits of soils from surfaces by applying to such surfaces a caustic, an acid-base color indicator, and thereafter applying an aqueous acidic solution to substantially neutralize the caustic, such as to a pH between about 4 and 10.5. When the caustic has been substantially neutralized, a color change takes place due to the presence of the acid-base color indicator thereby indicating to the user that the surface can be wiped clean without the need of rubber gloves or the worry of skin irritation. In a preferred embodiment, the method comprises applying to such surfaces a caustic alkali foam containing an acid-base color indicator, and then applying sufficient aqueous acidic solution to the surface so as to substantially neutralize the caustic and to effect a change in color of the caustic. In the alternative the acid-base indicator may be included in the aqueous acidic solution or may be applied apart from either the caustic or the acid.
We prefer that the caustic cleaner be in the form of a highly caustic alkali foam that is dispensed from an aerosol can. The caustic foam is left on the surface long enough to do its job, generally about 20-30 minutes in the case of ovens. The concentration of caustic used as percent.free hydroxyl may be from about 5 percent to about percent or more, preferably about 7-8 percent. Any strong caustic alkali may be used, such as sodium hydroxide or potassium hydroxide or mixtures thereof. It may be in the form of a water solution, and it is preferable that a surfactant or combination of surfactants be employed to impart foaming characteristics. The surfactant may be either anionic or nonionic, including but not restricted to anionic surfactants such as alkyl aryl sulfonates,.alcohol or fatty acid sulfonates or ether sulfates, alkyl amide or ester sulfonates, and fatty acid glycerol ester sulfates or ether sulfonates; and nonionic surfactants such as ethoxylated alcohols and alkylphenols, alkyanolamides, and block copolymers of ethylene and propyleneglycol. In addition a suitable potassium or sodium soap may optionally be added and may consist of various combinations of tallow, cocoa, red oil, tall oil, stearic and oleic fatty acids. A small amount of hexylene or propylene glycol may be added as a solubilizer; and various other ingredients may be added for their known effects such as sodium carboxy methyl cellulose or starch as thickening agents to aid foam adherence to the surface, and water soluble silicones as foam boosters and soil releaseagents. An example of a preferred caustic foamcleaner to be dispensed from an aerosol container is:
Ingredient 94 by weight 45% Potassium hydroxide l9.l7 Stearic acid 0.5 Oleic acid 4.8 Hexylene glycol 4.0 Acid-base indicator 0.2 Water 7l.4
Preferably 90-60 percent proportion of the above preferred cleaner is added, to an aerosol container along with 4-10 percent of a liquefied propellant for example fluorocarbons such as Freon 12 or Freon 114 or mixtures thereof or known hydrocarbon propellants.
The neutralizer should be sufiiciently acidic to reduce the alkalinity of the caustic to a relatively safe level. Suitable active ingredients include any generally weak acid or acid salt, and the following are preferred: sodium dihydrogen phosphate, citric acid, hemi sodium phosphate, carbamide phosphoric acid, gluconic acid, ethylene diamine tetracetic acid, phosphoric acid, and any appropriate combinations thereof. Other acids such as dilute mineral acids may be used but generally in low concentration or very dilute form. The acid is preferably present in about 10 3 to l0"6 moles per liter hydrogen ion concentration; but this is widely variable since merely more of lower concentrations and less of higher concentrations will be used to substantially neutralize the caustic. An example of a preferred neutralizer to be dispensed from an aerosol container is:
It is preferred to add a defoamer to aid in the penetration of the acid or acid salt into the caustic foam. In the alternative the incorporation of a soap in the first stage aids in defoaming by the neutralizer acting to convert the soap to a fatty acid.
Suitable acid-base indicators include any that effect a color or change or color at a pH of between about 4 and about 1 l and include but are not restricted to phenolphthalein, thymolphthalein, brilliant yellow, thymol blue, cresol purple, neutral red, phenol red, bromthymol blue, chlorphenol red, methyl red, bromcresol green, and alizarine yellow. The acidbase indicator may be added to the first stage formulation, thereby visibly coloring the caustic foam i.e., phenolphthalein in about 0.2 percent by weight concentration will produce a red foam in the above described specific preferred caustic, thymolphthalein will produce blue, brilliant yellow will produce orange, and meta cresol purple will produce purple. After the caustic has been applied and allowed sufficient time to work, the second stage neutralizer would be sprayed on prior to wiping. The neutralizer renders the caustic safe and the safe level is indicated by a change in color of the foam. Thus when a caustic foam that includes phenolphthalein is sprayed on the surface to be cleaned a red color is developed. When the neutralizer is applied the color disappears as the foam is substantially neutralized. Thymolphthalein indicator would also turn colorless, brilliant yellow indicator would become yellow and meta cresol purple would also become yellow. Bromthymol blue will change from blue to yellow and neutral red from light brown to red.
Although the compositions of the present invention may be applied by brushing or daubing, they are preferably applied from two separate aerosol cans and/or spr'ay bottles. As a further alternative the two-formulations may be applied via separate nozzles of a compartmentalized aerosol or via separable bottle aerosol nozzle and propellant combinations, and like means.
Thisinvention is still further illustrated by specific examples, which are not to be construed as composition limitations upon the scope thereof.
EXAMPLE I .Exemplary caustic formulations were prepared as set forth in Table 1. Each of the formulations was added to an aerosol container, using about -96 percent of the formulation and about 4-l0 percent of a suitable propellant such as dichloro difluoromethane (Freon 12), tetrafluoro dichloro ethane (Freon 114), pentafluoro monochloro ethane (Freon 115), trifluoro trichloro ethane (Freon 113) cyclic hexafluoro dichloro butane (Freon C 316), octafluoropropane (Freon 218), cyclic octafluoro butane (Freon C 318), propane, butane, pentane, isobutane, hexane, eptane, octane, nonane and decane, or mixtures thereof.
A preferred acidic formulation was prepared as set forth hereinabove. It was packaged in a spray bottle and also in an aerosol can propelled with carbon dioxide, nitrogen, nitrous oxide or a combination of Freon 12, Freon l l and Freon l 14.
The examples set forth in Table l were sprayed upon standard soiled panels. The panels had vitreous porcelain surfaces and the soil resulted from deposits of general organic food constituents, including butter, that had been subjected to about 350F. heat for 30 minutes. All products formed good initial foams that were evaluated for stability and adhesion after a 20-minute period. The panels were then sprayed with the neutralizing formulation until a change in color was observed. The foams then broke and the substantially neutralized residues were wiped off the panels with a cloth. No burns or skin irritation occurred. Where heavy spots of soil deposit remained, the panel was treated a second time. All soil was removed.
TABLE I 3. The method of removing deposits of calcined food soils from surfaces, which comprises applying to said surfaces a highly caustic foam having about 5 percent or more of free hydroxyl and containing an amount of an acid-base indicator that will roduce a color change at a H of about 4 to about 11; and t en applying an aqueous acr no solution to substantially neutralize-the caustic foam to produce a change in color of said foam.
43113 m e t hod of removing deposits of calcined food soils Example, percent by weight of ingredient Ingredient:
50% potassium hydroxide Surfactant (expressed as fatty acid). Ilexylono or propylene glycol. Water Thymolphthalein Phenolphthalein.. Brilliant yellow... Meta cresol purple. Para-nitro phenol...
Methyl red Phenol red Carboxymethyl cellulose 0.2
Total 100. 0 100. 0 100. 0 100. 0 100. 0 100.0 100.0
Color of caustic foam Blue Red Orange.-- Purple.... Yellow Yellow Red. Initial foam stability G d Good. G d Good..... Good. Good Good. Foam Stability, minutes Good. Good. Goo Poor Poor Good. Foam adhesion, 20 minutes..... Fair,...... Poor Poor Poor Poor.. Poor Poor. Neutralized color Colorless.. Colorless.. Yellow.. Colorless.. ed. Yellow. pH range of color. 9.3- 8.0- 7. 4- 7.0- 6. 2 8.0 Change l0.5....... 9.8 9.0 5.0 4.4.... 6.4. Soil removal Good... Good..... Good..... ood- Good..... G d-.... Good.
1 Color slightly unstable.
1 All foams were substantially neutralized by spraying ona% phosphate.
While this invention has been described with respect to specific embodiments of the method of removing deposits of soils from surfaces, such is by way of illustration and not in limitation; and it is to be understood that variations and modifications thereof obvious to those skilled the art may be made without departing from the spirit or scope of this inventron.
What is claimed is: g l
1. The method of removing deposits of soil from surfaces which comprises applying to said surfaces a caustic alkali having about 5 percent or more of free hydroxyl, said caustic containing an acid-base indicator that changes color at a pH weak acid solution of either citric acid or sodium hydrogen from surfaces which comprises applying to said surfaces an alkaline material containing a caustic alkali having about 5 percent or more of free hydroxyl and an acid-base indicator that produces a color change at a pH of about 4 to about 1 l; and then applying an aqueous solution which is sufficiently acidic to substantially neutralize the alkaline material and to change the color of the alkaline material.
5. The method of claim 4 in which said acid-base indicator is selected from the group consisting of phenolphthalein, thymolphthalein, brilliant yellow, meta cresol purple, thymol blue, neutral red, phenol red, methyl red, paranitro phenol and bromthymol blue.
|Cited Patent||Filing date||Publication date||Applicant||Title|
|US1572848 *||27 Aug 1924||9 Feb 1926||American Sheet & Tin Plate||Removal of oxids from ferrous metal|
|US1849535 *||19 Apr 1929||15 Mar 1932||Kohnstamm & Co Inc H||Laundry souring composition and method|
|US2034361 *||23 Mar 1929||17 Mar 1936||Sutton Roy C||Alkaline detergent powder and method of making the same|
|US2502881 *||17 Oct 1945||4 Apr 1950||Weston Parker Elizabeth||Household cleaning composition|
|US2994664 *||19 Feb 1958||1 Aug 1961||Nalco Chemical Co||Dry acid cleaning compositions|
|US3031408 *||7 Aug 1959||24 Apr 1962||B T Babbitt Inc||Aerosol oven cleanser|
|US3042621 *||1 Nov 1957||3 Jul 1962||Colgate Palmolive Co||Detergent composition|
|US3042622 *||1 Nov 1957||3 Jul 1962||Colgate Palmolive Co||Abrasive cleaning composition|
|US3511707 *||8 May 1967||12 May 1970||North American Detergent Corp||Method of cleaning a stone surface and composition therefor|
|Citing Patent||Filing date||Publication date||Applicant||Title|
|US4006091 *||14 Mar 1975||1 Feb 1977||Amway Corporation||Plastic bottle storable oven cleaner|
|US4390465 *||22 Jun 1981||28 Jun 1983||Fremont Industries, Inc.||Low temperature composition for plating pretreatment of ferrous metals|
|US4683008 *||12 Jul 1985||28 Jul 1987||Sparkle Wash, Inc.||Method for cleaning hard surfaces|
|US4965063 *||2 Aug 1988||23 Oct 1990||Irene Casey||Cleaner and disinfectant with dye|
|US5154917 *||11 Sep 1990||13 Oct 1992||Beecham Inc.||Color change mouthrinse|
|US5223245 *||11 Aug 1992||29 Jun 1993||Beecham Inc.||Color change mouthrinse|
|US5482654 *||9 Nov 1994||9 Jan 1996||Warnaway Corporation||Safety indicator system|
|US5626685 *||24 May 1994||6 May 1997||Spindler; William E.||Method of removing a water insoluble surface coating from a surface|
|US5670469 *||6 Jan 1995||23 Sep 1997||Texas Research Institute||Methods and compositions for cleaning and decontamination|
|US5770222 *||7 Jun 1995||23 Jun 1998||Imarx Pharmaceutical Corp.||Therapeutic drug delivery systems|
|US5776429 *||30 Apr 1996||7 Jul 1998||Imarx Pharmaceutical Corp.||Method of preparing gas-filled microspheres using a lyophilized lipids|
|US5803795 *||12 Jul 1996||8 Sep 1998||Teisan Kabushiki Kaisha||Method of treating inner surface of high-pressure gas vessel|
|US5830430 *||21 Feb 1995||3 Nov 1998||Imarx Pharmaceutical Corp.||Cationic lipids and the use thereof|
|US5842815 *||21 Nov 1996||1 Dec 1998||Arthur Michael Rogers Howes||Chemical treatment of treading surfaces|
|US5846517 *||30 Jan 1997||8 Dec 1998||Imarx Pharmaceutical Corp.||Methods for diagnostic imaging using a renal contrast agent and a vasodilator|
|US5853752 *||6 Jun 1995||29 Dec 1998||Imarx Pharmaceutical Corp.||Methods of preparing gas and gaseous precursor-filled microspheres|
|US5922304 *||9 Mar 1995||13 Jul 1999||Imarx Pharmaceutical Corp.||Gaseous precursor filled microspheres as magnetic resonance imaging contrast agents|
|US5935553 *||25 Nov 1996||10 Aug 1999||Imarx Pharmaceutical Corp.||Methods of preparing gas-filled liposomes|
|US5985246 *||8 Jul 1997||16 Nov 1999||Imarx Pharmaceutical Corp.||Contrast agents for ultrasonic imaging and methods for preparing the same|
|US5997898 *||6 Jun 1995||7 Dec 1999||Imarx Pharmaceutical Corp.||Stabilized compositions of fluorinated amphiphiles for methods of therapeutic delivery|
|US6001335 *||18 Jun 1996||14 Dec 1999||Imarx Pharmaceutical Corp.||Contrasting agents for ultrasonic imaging and methods for preparing the same|
|US6028066 *||2 Jul 1997||22 Feb 2000||Imarx Pharmaceutical Corp.||Prodrugs comprising fluorinated amphiphiles|
|US6033645 *||19 Jun 1996||7 Mar 2000||Unger; Evan C.||Methods for diagnostic imaging by regulating the administration rate of a contrast agent|
|US6033646 *||19 Feb 1998||7 Mar 2000||Imarx Pharmaceutical Corp.||Method of preparing fluorinated gas microspheres|
|US6056938 *||5 May 1998||2 May 2000||Imarx Pharaceutical Corp.||Cationic lipids and the use thereof|
|US6071494 *||28 Aug 1998||6 Jun 2000||Imarx Pharmaceutical Corp.||Methods for diagnostic imaging using a contrast agent and a renal vasodilator|
|US6071495 *||2 Oct 1997||6 Jun 2000||Imarx Pharmaceutical Corp.||Targeted gas and gaseous precursor-filled liposomes|
|US6088613 *||7 Jun 1995||11 Jul 2000||Imarx Pharmaceutical Corp.||Method of magnetic resonance focused surgical and therapeutic ultrasound|
|US6090800 *||6 May 1997||18 Jul 2000||Imarx Pharmaceutical Corp.||Lipid soluble steroid prodrugs|
|US6117414 *||10 Nov 1997||12 Sep 2000||Imarx Pharmaceutical Corp.||Method of computed tomography using fluorinated gas-filled lipid microspheres as contract agents|
|US6120751 *||8 Sep 1997||19 Sep 2000||Imarx Pharmaceutical Corp.||Charged lipids and uses for the same|
|US6123923 *||18 Dec 1997||26 Sep 2000||Imarx Pharmaceutical Corp.||Optoacoustic contrast agents and methods for their use|
|US6139819 *||17 Sep 1997||31 Oct 2000||Imarx Pharmaceutical Corp.||Targeted contrast agents for diagnostic and therapeutic use|
|US6143276 *||21 Mar 1997||7 Nov 2000||Imarx Pharmaceutical Corp.||Methods for delivering bioactive agents to regions of elevated temperatures|
|US6146657 *||1 Nov 1996||14 Nov 2000||Imarx Pharmaceutical Corp.||Gas-filled lipid spheres for use in diagnostic and therapeutic applications|
|US6156292 *||20 Dec 1996||5 Dec 2000||Sonus Pharmaceuticals, Inc.||Gaseous ultrasound contrast media and method for selecting gases for use as ultrasound contrast media|
|US6231834||2 Dec 1997||15 May 2001||Imarx Pharmaceutical Corp.||Methods for ultrasound imaging involving the use of a contrast agent and multiple images and processing of same|
|US6245319||24 Mar 2000||12 Jun 2001||Sonus Pharmaceuticals, Inc.||Colloidal dispersions of perfluoropentane|
|US6315981||19 Mar 1999||13 Nov 2001||Imarx Therapeutics, Inc.||Gas filled microspheres as magnetic resonance imaging contrast agents|
|US6391226||3 May 1999||21 May 2002||Laboratoires Choisy Ltee||Coating or sealing composition|
|US6403056||31 Mar 2000||11 Jun 2002||Imarx Therapeutics, Inc.||Method for delivering bioactive agents using cochleates|
|US6414139||3 Sep 1996||2 Jul 2002||Imarx Therapeutics, Inc.||Silicon amphiphilic compounds and the use thereof|
|US6416740||11 May 1998||9 Jul 2002||Bristol-Myers Squibb Medical Imaging, Inc.||Acoustically active drug delivery systems|
|US6443898||7 Jun 1995||3 Sep 2002||Imarx Pharmaceutical Corp.||Therapeutic delivery systems|
|US6444660||3 Feb 2000||3 Sep 2002||Imarx Therapeutics, Inc.||Lipid soluble steroid prodrugs|
|US6461586||10 Jul 2000||8 Oct 2002||Imarx Therapeutics, Inc.||Method of magnetic resonance focused surgical and therapeutic ultrasound|
|US6479034||17 Jul 1998||12 Nov 2002||Bristol-Myers Squibb Medical Imaging, Inc.||Method of preparing gas and gaseous precursor-filled microspheres|
|US6521211||3 Feb 1999||18 Feb 2003||Bristol-Myers Squibb Medical Imaging, Inc.||Methods of imaging and treatment with targeted compositions|
|US6528039||18 Jun 1997||4 Mar 2003||Bristol-Myers Squibb Medical Imaging, Inc.||Low density microspheres and their use as contrast agents for computed tomography and in other applications|
|US6537246||18 Jun 1997||25 Mar 2003||Imarx Therapeutics, Inc.||Oxygen delivery agents and uses for the same|
|US6548047||15 Sep 1997||15 Apr 2003||Bristol-Myers Squibb Medical Imaging, Inc.||Thermal preactivation of gaseous precursor filled compositions|
|US6551576||31 Mar 1998||22 Apr 2003||Bristol-Myers Squibb Medical Imaging, Inc.||Container with multi-phase composition for use in diagnostic and therapeutic applications|
|US6576220||10 May 2001||10 Jun 2003||Imarx Therapeutics, Inc.||Non-invasive methods for surgery in the vasculature|
|US6585955||31 Oct 1996||1 Jul 2003||Bracco International B.V.||Long-lasting aqueous dispersions or suspensions of pressure-resistant gas-filled microvesicles and methods for the preparation thereof|
|US6592846||12 May 2000||15 Jul 2003||Bracco International B.V.||Long-lasting aqueous dispersions or suspensions of pressure resistant gas-filled microvesicles and methods for thereof preparation thereof|
|US6613306||22 Sep 1999||2 Sep 2003||Bracco International B.V.||Ultrasound contrast agents and methods of making and using them|
|US6620404||28 Sep 2000||16 Sep 2003||Amersham Health A/S||Gaseous ultrasound contrast media and method for selecting gases for use as ultrasound contrast media|
|US6638767||21 Dec 2000||28 Oct 2003||Imarx Pharmaceutical Corporation||Methods for delivering compounds into a cell|
|US6743779||29 Apr 1997||1 Jun 2004||Imarx Pharmaceutical Corp.||Methods for delivering compounds into a cell|
|US6773696||25 Oct 2002||10 Aug 2004||Bristol-Myers Squibb Medical Imaging, Inc.||Contrast agent comprising low density microspheres|
|US6808720||15 Jan 2002||26 Oct 2004||Imarx Therapeutics, Inc.||Charged lipids and uses for the same|
|US6814816||3 Oct 2003||9 Nov 2004||Unilever Home & Personal Care Usa Division Of Conopco, Inc.||Indicator kit|
|US6875420||18 Jul 1997||5 Apr 2005||Amersham Health As||Method of ultrasound imaging|
|US6881397||4 Feb 2002||19 Apr 2005||Bracco International B.V.||Long-lasting aqueous dispersions or suspensions of pressure-resistant gas-filled microvesicles and methods for the preparation thereof|
|US6884407||18 May 2000||26 Apr 2005||Bristol-Myers Squibb Pharma Company||Methods for diagnostic imaging involving the use of a contrast agent and a coronary vasodilator|
|US6896875||23 Aug 2002||24 May 2005||Bracco International B.V.||Mixable combination for generating a suspension of stable microbubbles for ultrasonic imaging|
|US6989141||12 Apr 2002||24 Jan 2006||Bracco International B.V.||Ultrasound contrast agents and methods of making and using them|
|US6998107||10 Jun 2004||14 Feb 2006||Bristol-Myers Squibb Pharma Comapany||Composition comprising low density microspheres|
|US7078015||8 Nov 2004||18 Jul 2006||Imarx Therapeutics, Inc.||Ultrasound imaging and treatment|
|US7083572||26 Mar 2002||1 Aug 2006||Bristol-Myers Squibb Medical Imaging, Inc.||Therapeutic delivery systems|
|US7083778||12 Mar 2003||1 Aug 2006||Bracco International B.V.||Ultrasound contrast agents and methods of making and using them|
|US7105151||6 Jan 2003||12 Sep 2006||Imarx Therapeutics, Inc.||Oxygen delivery agents and uses for the same|
|US7329402||13 Jan 2003||12 Feb 2008||Imarx Pharmaceutical Corp.||Methods of imaging and treatment|
|US7344705||18 Oct 2005||18 Mar 2008||Bristol-Myers Squibb Medical Imaging, Inc.||Composition comprising low density microspheres|
|US7452551||30 Oct 2000||18 Nov 2008||Imarx Therapeutics, Inc.||Targeted compositions for diagnostic and therapeutic use|
|US7550422||4 Oct 2005||23 Jun 2009||The Procter & Gamble Company||Composition with a metal-complexing dye and surfactant|
|US7612033||18 Mar 2004||3 Nov 2009||Imarx Pharmaceutical Corp.||Methods for delivering compounds into a cell|
|US7651989||29 Aug 2003||26 Jan 2010||Kimberly-Clark Worldwide, Inc.||Single phase color change agents|
|US7858568||22 Jan 2010||28 Dec 2010||Kimberly-Clark Worldwide, Inc.||Single phase color change agents|
|US7910531||13 Jun 2005||22 Mar 2011||C2C Technologies Llc||Composition and method for producing colored bubbles|
|US8012457||2 Jun 2005||6 Sep 2011||Acusphere, Inc.||Ultrasound contrast agent dosage formulation|
|US8067350||27 Apr 2007||29 Nov 2011||Kimberly-Clark Worldwide, Inc.||Color changing cleansing composition|
|US8084056||22 Sep 2003||27 Dec 2011||Lantheus Medical Imaging, Inc.||Preparation of a lipid blend and a phospholipid suspension containing the lipid blend|
|US8586005||6 Aug 2007||19 Nov 2013||Acusphere, Inc.||Ultrasound contrast agent dosage formulation|
|US8658205||1 Aug 2011||25 Feb 2014||Lantheus Medical Imaging, Inc.||Preparation of a lipid blend and a phospholipid suspension containing the lipid blend|
|US8685441||23 Jul 2013||1 Apr 2014||Lantheus Medical Imaging, Inc.||Preparation of a lipid blend and a phospholipid suspension containing the lipid blend|
|US8747892||25 Jul 2013||10 Jun 2014||Lantheus Medical Imaging, Inc.||Preparation of a lipid blend and a phospholipid suspension containing the lipid blend|
|US20020150539 *||2 Apr 2002||17 Oct 2002||Unger Evan C.||Ultrasound imaging and treatment|
|US20040065350 *||3 Oct 2003||8 Apr 2004||Unilever Home & Personal Care Usa, Division Of Conopco, Inc.||Indicator kit|
|US20040126322 *||3 Dec 2003||1 Jul 2004||Bracco International B.V.||Polymeric gas or air filled microballoons usable as suspensions in liquid carriers for ultrasonic echography|
|US20040173244 *||31 May 2002||9 Sep 2004||Werner Strothoff||Cleaning method for removing starch|
|US20040180004 *||20 Feb 2004||16 Sep 2004||Bracco International B.V.||Stable microbubble suspensions as enhancement agents for ultrasound echography and dry formulations thereof|
|US20040197269 *||26 Apr 2004||7 Oct 2004||Bracco Research S.A.||Ultrasound contrast media, contrast agents containing the media and method|
|US20040208826 *||26 Mar 2004||21 Oct 2004||Bracco International B.V.||Ultrasound contrast agents and methods of making and using them|
|US20050019266 *||23 Jan 2003||27 Jan 2005||Unger Evan C.||Novel targeted compositions for diagnostic and therapeutic use|
|US20050031543 *||7 Apr 2004||10 Feb 2005||Amersham Health As||Contrast agents|
|US20050049157 *||29 Aug 2003||3 Mar 2005||Kimberly-Clark Worldwide, Inc.||Single phase color change agents|
|US20050058605 *||13 Oct 2004||17 Mar 2005||Michel Schneider||Long-lasting aqueous dispersions or suspensions of pressure-resistant gas-filled microvesicles and methods for the preparation thereof|
|US20050123482 *||8 Nov 2004||9 Jun 2005||Unger Evan C.||Ultrasound imaging and treatment|
|US20050196342 *||10 Feb 2005||8 Sep 2005||Jo Klaveness||Contrast agents|
|US20050271591 *||2 Jun 2005||8 Dec 2005||Acusphere, Inc.||Ultrasound contrast agent dosage formulation|
|US20060004110 *||13 Jun 2005||5 Jan 2006||Sabnis Ram W||Composition and method for producing colored bubbles|
|US20060034771 *||22 Sep 2005||16 Feb 2006||Bracco International B.V.||Ultrasound contrast agents and methods of making and using them|
|US20060236470 *||28 Mar 2006||26 Oct 2006||Sabnis Ram W||Novelty compositions with color changing indicator|
|USRE39146||15 Jul 1998||27 Jun 2006||Bracco International B.V.|
|CN101035887B||30 Sep 2005||9 Mar 2011||宝洁公司||A composition with a metal-complexing dye and surfactant|
|WO1996020995A1 *||5 Jan 1996||11 Jul 1996||Alan Bray||Compositions containing a visible colorant and methods for cleaning and decontamination|
|WO2006041739A1 *||30 Sep 2005||20 Apr 2006||Procter & Gamble||A composition with a metal-complexing dye and surfactant|
|WO2008117233A1 *||25 Mar 2008||2 Oct 2008||Procter & Gamble||Liquid detergent composition system having a visual indication change|
|WO2008117235A1 *||25 Mar 2008||2 Oct 2008||Procter & Gamble||Liquid composition system having a visual indication change|
|WO2008141847A1 *||28 Feb 2008||27 Nov 2008||Unilever Plc||Triphenyl methane and xanthene pigments|
|U.S. Classification||134/27, 510/197, 134/40, 436/163|
|International Classification||C11D3/00, C11D7/06, C11D7/02, C11D3/40|
|Cooperative Classification||C11D3/40, C11D3/0057, C11D7/06|
|European Classification||C11D3/00B11, C11D7/06, C11D3/40|