|Publication number||US3486539 A|
|Publication date||30 Dec 1969|
|Filing date||28 Sep 1965|
|Priority date||28 Sep 1965|
|Also published as||DE1548992A1, DE1548992B2, DE1548992C3|
|Publication number||US 3486539 A, US 3486539A, US-A-3486539, US3486539 A, US3486539A|
|Original Assignee||Jacuzzi Bros Inc|
|Export Citation||BiBTeX, EndNote, RefMan|
|Patent Citations (8), Referenced by (147), Classifications (22)|
|External Links: USPTO, USPTO Assignment, Espacenet|
Dec. 30, 1969 3 c. JACU ZZI 3,486,539
LIQUID DISPENSING AND METERING ASSEMBLY Filed Sept. 28, 1965 Z SheetS-Sheet 1 M/l/E/VTOR SAND/D0 JA GUZZ/ BY WARREM BROSLEECYPHER 8 ANGL/M .4 TTOENEYS Dec. 30, 1969 c) cum I 3,486,539
LIQUID DISPENSING'AND METERING ASSEMBLY Filed Sept. 28, 1965 2 Sheets-Sheet 2 a 400 r i" 9/ 2 E s00 USA BLE r 3 RAM E v 1' E 200 m @100 E 0 I0 20 a0 40 5o 60 VOLUME (00) //v VE/V r01? E2 8. OAA/D/DO JA 0022/ WA HREN, BR 08L E'R, crpnsn .9 AN 61. m
ATTORNEYS United States Patent 3,486,539 LIQUID DISPENSING AND METERING ASSEMBLY Candido Jacuzzi, Lafayette, Calif., assignor to Jacuzzi Bros., Incorporated, a corporation of California Filed Sept. 28, 1965, Ser. No. 490,787 Int. Cl. B65b 1/04, 9/04; B67d /58 US. Cl. 141-329 11 Claims ABSTRACT OF THE DISCLOSURE My invention relates to a liquid dispensing and metering assembly, and more particularly to an assembly particularly adaptable for use in the medical field, insofar as it relates to the supplying of liquids, other than orally, to patients, or to the withdrawal of fluids from body cavities.
In the treatment of patients, it is often necessary to supply such patients with liquids other than by mouth. In intravenous feeding, for example, liquids are administered through a needle introduced into a vein. Ofttimes, in the treatment of localized cancers, solutions are introduced in concentrated form at th site of such condition. Other situations calling for the infusion of liquids into the body of a patient are Well known to the medical profession. In most cases where such is necessary or desirable, the flow rate should be held substantially constant over a substantial period of time, and at a pressure rate which in most instances would be quite low, for example, of the order of 400 millimeters of mercury or less. 7
Other conditions prevail Where instead of supplying liquid to a patient, withdrawal of fluids from a body cavity of a patient may become desirable in the treatment of a patient.
Among the objects of my invention are:
(1) To provide a novel and improved liquid dispensing and metering assembly;
(2) To provide a novel and improved liquid dispensing and metering assembly capable of supplying liquid at substantially a constant flow rate and pressure over a period of time;
(3) To provide a novel and improved liquid dispensing and metering assembly which can dispense liquid at low, substantially constant flow rate and pressure over a substantial period of time;
(4) To provide a novel and improved liquid dispensing and metering assembly capable of prolonged infusion of liquid into the human body at a slow but constant rate;
(5) To provide a novel and improved liquid dispensing and metering assembly capable of use in the production of a sub-atmospheric condition, and employable in the removal of fluids from an external source, such as a body cavity of a patient under treatment;
(6) To provide a novel and improved means for holding liquid under pressure, and adapted to discharge the same at a substantially constant pressure over a period of time;
(7) To provide a novel and improved means for holding liquid under pressure and capable of dispensing same at a substantially constant pressure despite a decrease in volume of said holding means during discharge;
(8) To provide a novel and improved metering assembly for a liquid dispenser;
3,486,539 Patented Dec. 30, 1969 (9) To provide a novel and improved metering assembly for a liquid dispenser, capable of metering liquid at low pressure and low flow rate;
(10) To provide a novel and improved liquid dispensing and metering assembly of light weight, and which can be manufactured sufliciently economically to justify discarding the same after one use thereof, and thus provide what is customarily referred to as a throwaway item.
Additional objects of my invention will be brought out in the following description of a preferred embodiment of the same, taken in conjunction with the accompanying drawings wherein,
FIGURE 1 is a longitudinal view in section through a liquid dispensing and metering assembly of the present invention, depicting the same prior to filling and use thereof;
FIGURE 2 is a view similar to that of FIGURE 1 but illustrating the same in its filled condition and ready for use;
FIGURE 3 is an enlarged fragmentary view of section, through the coupling portion of the assembly of FIG- URE 2;
FIGURE 4 is a front end view in elevation of a receptacle assembly constituting a portion of the assembly of FIGURES 1 and 2;
FIGURE 5 is an end view in elevation of a hub constituting a component of a coupling involved in the apparatus of FIGURE 1;
FIGURE 6 is a longitudinal view in section of an assembly utilizing the principle of the apparatus of FIG- URE 1 in the removal of fluids from a body cavity of a patient;
FIGURE 7 is a view similar to that of FIGURE 6, but depicting the assembly in a partially discharged condition; and
FIGURE 8 is a curve depicting dispensing characteristics of the apparatus of the present invention, when designed for use in the medical field where a discharge flow at low rate and substantially constant pressure over a prolonged period of time is a prerequisite.
Referring to the drawings for details of my invention in its preferred form, the same relates to a liquid dispensing and metering assembly made up of a unique receptacle assembly 1 and a novel metering assembly 3, connectable together in functional relationship by a disconnectable coupling 5.
The receptacle assembly comprises a receptacle 7 formed from a tube of expansible material such as a polymer, one end of the tube being closed off, preferably by a clamping ring 9, leaving the other end open for stretching over the neck 11 of a connector 13 which also forms one component of the coupling 5. An O-ring 15 about the attached end of the tube serves to anchor the same more securely, the neck portion of the connector having an O-ring recess 17 to assure retention of the tube about the neck portion of the connector.
The connector 13 comprises a head 19 from which the neck 11 extends, and has a passageway 21 therethrough. The neck end of the coupling is formed with a counter bore to receive a syringe type plug or stopper 23 which is held in its installed position against a shoulder formed by the counter bore, by a retainer sleeve 25 snugly fitting into the neck, and preferably adhesively secured or bonded therein. A wide diametrical slot 27 across the face of the conector, creates a pair of oposing side walls 29, 31, which are undercut to form interlock grooves 33, 35 respectively, while the floor of the slot is recessed about the passageway 21 to form a teat 32.
The plug or stoper 23, while it normally closes the entrance to the tube, is capable of being penetrated by the needle of a syringe, of the type conventionally employed in the medical field, and such type of syringe can be utilized in filling the tube with liquid under pressure, the tube expanding under such pressure as the liquid is forced into it. Upon withdrawal of the needle, the liquid will be trapped under pressure in the tube.
Surrounding the tube is a sheath or packet 39, which in the preferred form of the invention under consideration, may be of nylon film or other cheap flexible material, and such sheath will function to protect the tube and limit the radial expansion thereof as is filled.
The jacket, at one end, is preferably anchored about the head of the connector, to which it is retained by an O-ring 43, the opposite end of the jacket being left open.
In its unfilled condition, the receptacle assembly, as thus described, is limp and flexible, but when filled to capacity, the tube will inflate to the limit permitted by the jacket and become semi-rigid.
As an aid in filling the receptacle, a string 45 preferably of nylon, because of its inherent strength, is affixed to the closed off end of the tube, which can readily be accomplished during the application of the clamping ring, by looping the string through the clamping ring While applying the ring.
In filling such receptacle, care should be exercised to eliminate all air from the tube during the process, and this is particularly important in connection with the utilization of the device in the treatment of patients for certain conditions.
With this in mind, the receptacle is held upright with the connector end uppermost, and while so held, approximately twelve to fifteen cubic centimeters of the solution to be utilized, is forced into the tube from a syringe, the needle of which has been inserted through the plug or stopper. While retaining the syringe in its inserted position, the tube is manipulated to work all air to the space above the liquid level, whereupon, the syringe plunger is withdrawn to suck out the air. The syringe can then be removed leaving the unfilled portion of the tube evacuated and free of air.
The receptacle is then suspended from a hook by means of the loop of nylon string, following which a syringe containing the desired liquid, is again applied and the solution is slowly injected while the operator manually pinches the tube at a point close to the syringe needle, to assure starting a bubble forming at the entrance end of the tube.
As the bubble continues to grow with the increase of liquid into the tube, tension on the string is increased until the tube has expanded, along its length, into contact with the jacket.
The receptacle as thus filled is ready for use in discharging is contents and for this purpose I provide a hub 51 which constitutes the other half of the coupling. This hub at its coupling end, is formed with diametrically located cam fins 53, 55 adapted to fit into the interlock grooves 33, 35 of the connector component of the receptacle assembly, and by a partial turn of the hub, interlock and couple the hub to the receptacle asembly in a manner which, under normal conditions, will assure retention of the hub against accidental uncoupling.
The hub is preferably molded with an extension 57 terminating in a head 59 contoured to permit of forcible entry into an end of a discharge tube 60 of rubber or like material, to retain the same fixedly Secured to the hub against accidental dislodgment therefrom. A longitudinal passageway 61 through the hub is adapted to frictionally receive a cannula 63, such passageway, at the tube attachment end, being of a smaller diameter to match that of the inside diameter of the cannula, and at the same time form a shoulder 65 against which the cannula may abut, to permit pressure being applied to the cannula in puncturing the plug or stopper 23, and affect a flow connection with the interior of the rece tac e.
The coupling end of the passageway through the hub is preferably counter-sunk to provide suflicient flexibility during camming of the fins into the interlock grooves to facilitate such coupling.
Metering of the liquid as thus released from the receptacle under pressure, is accomplished by the meter ing assembly 3. Such metering assembly, in its preferred form, consists of a porous plug 71 in the tube and of such uniform porosity as to function as a meter in determining flow rate of liquid, such meter being preferably in conjunction with a porous fiber 73 also disposed in the tube 60 in spaced relationship to the meter, on the upstream side thereof. The calibration of the porous meter is a function of its built-in porosity, as well as its diameter and length, and these may be varied to meet required conditions. The meter plug 71 and filter 73 may be of ceramic or sintered metal, or any other suitable material capable of providing porosity having the desired characteristics.
The function of the filter is to assure that the liquid passing through the meter shall be entirely free of sediment or precipitates which might otherwise clog pores of the meter and alter the calibration value thereof. The present invention is particularly intended for use with liquids which are initially considered free of precipitate or sediment, and consequently the porous filter is really intended as a safeguard for the meter, against liquid which may accidentally have become slightly contaminated with solids, and to assure against clogging of the filter under such circumstances, the filter element is preferably of greater diameter than the meter element.
The plug 23 and cannula arrangement for withdrawing liquid from the receptacle 7, may be replaced by a needle valve assembly.
Inasmuch as the assembly of the present invention is intended for use but once before being discarded, it will be appreciated that the probability of impairment of the metering assembly through clogging or even partial clogging of the ceramic filter element can be effectively avoided.
In the device of FIGURE 5, for use in the withdrawal of fluids from external sources, such as fluids from a body cavity of a patient, advantage is taken of the fact that the receptacle of the assembly of FIGURES l and 2, contracts as it forces liquid therefrom, and consequently the basic structure of this assembly is included in the device of FIGURE 5.
In this device, an expandable tube 75 is housed in an airtight shell or jacket 79, through one end of which it discharges into a discharge line 81 through a metering means in the form of a manually controllable flow adjustable valve assembly 83 including a valve 85. This form of metering means may 'be utilized for this device in that flow of liquid is not required to be as precise and critical as when delivering liquid to a patient utilizing the assembly of FIGURES 1 and 2, and flow rates may be greater.
To the other end of the shell is connected an incoming line 84 through a similar manually controllable flow adjustable valve assembly 86 including a valve 87. The incoming line is connected to a source of fluid (not shown), from which it is desired to withdraw the fluid, and as liquid is discharged from the expandable tube 75, the reduction in volume thereof creates in the shell, a vacuum condition, which causes liquid or fluid to be withdrawn from the source into the shell.
The valve 87 in the incoming line may be adjusted to maximum permissible flow of the fluid to be withdrawn, while the actual rate of flow of such fluid will be determined by the adjustment of the valve in the discharge line.
The shell or jacket 79 may be of any suitable material, but should be sufficiently rigid to withstand the differential pressures developed during development of reduced pressures within the same, and preferably should be of a light transparent plastic to permit observation of the fluids drawn into it.
If a slow and precise evacuation of body fluids or liquids from other sources is desired, the coupling assembly and metering assembly of the apparatus of FIG- URE 1 may be relied on, otherwise the more conventional construction illustrated may be employed.
In connection with the many uses of the present invention in the medical field, and in certain other applica tions it is quite important that the flow rate in the discharge line shall be steady, and at a low and constant pressure. An important feature of the present invention accordingly lies in the ability to realize a discharge having these characteristics, and this I have been able to accomplish through the development of a receptacle which will discharge at a substantially constant pressure over a period of time, despite its decreasing volume during such discharge, and which when employed in co operation with the metering assembly, will provide a discharge flow to satisfy such requirements.
In FIGURE 8 of the drawings, I have depicted in phantom, the discharge characteristic curve 91 of an ideal receptacle, in terms of withdrawal performance, wherein I have plotted volume discharge from the receptacle against discharge pressure. From this curve it will be appreciated, that what is desired, is a discharge pressure which remains substantially constant throughout the entire discharge cycle.
I have discovered that this ideal curve can be approached through the use of pure gum rubber in the fabrication of the receptacle, for such rubber possesses the qualities required, namely low hysteresis, high tensile strength, high ultimate strength, high elasticity, and ,excellent recovery, besides being chemically compatible with liquids contemplated for use therewith. Such rubber is sometimes referred to as latex or surgical rubber.
The length and diameter of the tube used in the receptacle will determine the capacity of the receptacle assembly, while the thickness of the tube wall will establish the functioning pressure. The solid line curve 93 of FIG- URE 6 represents an actual curve obtained with a receptacle of pure gum rubber having a wall thickness of /32 of an inch, a length of 6 inches, an uninfiated diameter of of an inch and an inflated diameter of 1 inch.
From this curve, it becomes apparent that the specific receptacle considered, has a dispensing capacity of 50 cubic centimeters at a substantially constant pressure of approximately 414 millimeters of mercury, the slightly varying pressure at the beginning and end of the dispensing range, being acceptable in view of the relatively brief elements of time involved and the fact that the metering means, in throttling down the pressure, will tend to minimize such variations.
Being that the receptacle dispenses under positively applied pressure, as distinguished from gravity feed employed in conventional intravenous feeding procedure and the like, it no longer becomes necessary to maintain an elevated position of the receptacle with respect to the patient being treated, which in turn, required substantial immobilization of the patient.
The device of the present invention, can be strapped or otherwise attached to the patient, thus allowing the patient complete mobility and freedom of movement, with full assurance, due to the positive pressure involved in its operation, that the device will function smoothly and continpously, and will not require the repeated attention and adjustment demanded by apparatus which dispenses by gravity.
The receptacle and nylon jacket, being flexible will accommodate themselves to the body contour at the location of application, and thus may be readily concealed beneath ones clothing. To enhance this characteristics of the device, the connector, in lieu of being made circular, can be oval in contour.
While I have stressed the importance of the present invention in its use in the medical field, it will be apparent that the same may have use in other applications and fields, and accordingly while I have illustrated and described the same in its preferred form and in considerable detail, I do not desired to be limited in my protection to the specific details illustrated and described except as may be necessitated by the appended claims.
1. A liquid dispensing and metering assembly comprising a receptacle assembly having expansible characteristics, for holding liquid under pressure, and including a receptacle of a polymer having the characteristics of maintaining a substantially constant internal pressure in said receptacle throughout a range of decreasing volume of its contents, a flow passageway from said receptacle assembly, and means in said flow passageway for metering liquid from said receptacle assembly, and under pressure from said receptacle assembly.
2. A liquid dispensing and metering assembly in accordance with claim 1, characterised by a hypodermic type cap normally closing an opening in said receptacle, to enable filling thereof with a hypodermic type springe, and a flexible jacket surrounding said receptacle to limit expansion of said receptacle during such filling thereof.
3. A liquid dispensing and metering assembly in accordance with claim 1, characterised by said means for holding liquid under pressure including a receptacle of elastic material such as surgical rubber, adapted to maintain a substantially constant internal pressure in said receptacle throughout a range of decreasing volume of its contents, a hypodermic type cap normally closing an opening in said receptacle, to enable filling thereof with a hypodermic type syringe, and a flexible jacket of transparent plastic surrounding said receptacle to limit radial expansion of said receptacle during such filling thereof and permit observation thereof.
4. A liquid dispensing and metering assembly in accordance with claim 1, characterised by a disconnectable coupling between said receptacle means and said metering means, and having a flow passageway therethrough, said disconnectable coupling including a connector at an end of said receptacle having opposing interlock grooves on either side of said passageway, and a hub having oppositely located cam fins adapted to engage and frictionally lock in the interlock grooves of said connector.
5. A receptacle assembly for a liquid dispensing and metering assembly, comprising a receptacle of expansible material enabling said receptacle to expand under pressure of liquid forced into said receptacle and maintain pressure on such liquid upon completion of a filling operation, a closure for said receptacle having a flow passageway therethrough, means aflixing said receptacle at one end to said closure with said passageway in flow communication with said receptacle, and means for controlling flow through said passageway from a fully closed condition of said passageway, to enable one to maintain liquid in said receptacle under pressure of said receptacle, a collapsible jacket about said receptacle and affixed at one end to said closure and open at its other end.
6. A receptacle assembly in accordance with claim 5, characterised by said closure constituting a connector forming one component of a coupling.
' 7. A receptacle assembly in accordance with claim 5, characterised by said jacket being of transparent plastic.
8. A receptacle assembly in accordance with claim 5 characterised by said receptacle having means at its opposite end and accessible through the open end of said jacket for use in placing said receptacle under tension.
9. A receptacle assembly in accordance with claim 5, characterised by said jacket being of thin sheet plastic.
10. A receptacle assembly in accordance with claim 6, characterised by said connector including a head and neck portion, with said receptacle afiixed to said neck portion and said jacket being afiixed to said head portion.
7 8 11. A receptacle assembly in accordance with claim 6, 3,200,996 8/1965 Picatti 222--107 characterised by said connector having opposing interlock 3,303,898 2/ 1967 Bercaru 175228 grooves to either side of said flow passageway. 1,746,139 2/ 1930 Bijur.
2,480,558 8/1949 Dekiss 138-30 References Cited UNITED STATES PATENTS 5 HOUSTON s. BELL, TR., Primary Examiner 10/1929 Gleason.
5/1931 cafpellter- 128--272; 141382, 383, 387; 222189, 386.5; 239- 5/1932 Wilkes. 323 10/1932 Morse. 10
|Cited Patent||Filing date||Publication date||Applicant||Title|
|US1732579 *||11 Jun 1928||22 Oct 1929||Gleason Frederick H||Lubricating system|
|US1746139 *||5 Jun 1928||4 Feb 1930||Auto Research Corp||Chassis-lubricating installation|
|US1807059 *||25 Jan 1929||26 May 1931||Ideal Lubricator Company||Lubricating system|
|US1857992 *||22 Dec 1930||10 May 1932||Frederic Wilkes||Lubricating apparatus|
|US1881848 *||1 Apr 1929||11 Oct 1932||Alemite Corp||Lubricating apparatus|
|US2480558 *||9 Mar 1944||30 Aug 1949||Bendix Aviat Corp||Accumulator|
|US3200996 *||23 Mar 1964||17 Aug 1965||Joe E Picatti||Collapsible bag type applicator|
|US3303898 *||28 Oct 1963||14 Feb 1967||Mini Petrolului||Bearing sealing and lubricating device|
|Citing Patent||Filing date||Publication date||Applicant||Title|
|US3589470 *||24 Sep 1969||29 Jun 1971||Superior Mfg Co||Grease gun adapter|
|US3640276 *||9 Jan 1970||8 Feb 1972||Allis Chalmers Mfg Co||Apparatus for making intravenous or intra-arterial injections|
|US3640277 *||9 Dec 1968||8 Feb 1972||Marvin Adelberg||Medical liquid administration device|
|US3736954 *||20 May 1971||5 Jun 1973||Sparton Corp||Self-attaching check valve|
|US3785367 *||13 Mar 1972||15 Jan 1974||Pharmasel Division American Ho||Arterial blood sampler|
|US3817248 *||6 Nov 1972||18 Jun 1974||Alza Corp||Self powered device for delivering beneficial agent|
|US3850348 *||9 Feb 1973||26 Nov 1974||Anvar||Apparatus for injection of liquid|
|US3895631 *||4 Feb 1974||22 Jul 1975||Alza Corp||Liquid infusion unit|
|US3961725 *||9 Apr 1974||8 Jun 1976||Clark Richard A||Method and apparatus for dispensing fluids under pressure|
|US3965889 *||3 Jan 1975||29 Jun 1976||Commissariat A L'energie Atomique||Apparatus for the sampling of blood and the separation of plasma under anaerobic conditions|
|US3993069 *||18 Aug 1975||23 Nov 1976||Alza Corporation||Liquid delivery device bladder|
|US4201207 *||26 Nov 1976||6 May 1980||Alza Corporation||Bladder for liquid dispenser|
|US4204538 *||7 Jun 1978||27 May 1980||Imed Corporation||Cassette for intravenous controller|
|US4318400 *||18 Jan 1980||9 Mar 1982||Alza Corporation||Medical infusor|
|US4331147 *||1 Jul 1980||25 May 1982||Glasrock Products, Inc.||System for draining wounds|
|US4386929 *||19 Oct 1981||7 Jun 1983||Alza Corporation||Elastomeric bladder assembly|
|US4595006 *||16 Aug 1982||17 Jun 1986||Burke Dennis W||Apparatus for cemented implantation of prostheses|
|US4702397 *||18 Sep 1984||27 Oct 1987||Infusion Systems Corporation||Pressurized fluid dispenser|
|US4735239 *||19 Sep 1986||5 Apr 1988||Water Weenies, Inc.||Liquid projecting device|
|US4785859 *||22 Jun 1987||22 Nov 1988||Bengt Gustavsson||Variable volume vessel having a rigid cover and a flexible part receivable into the cover|
|US4787429 *||20 Jul 1987||29 Nov 1988||Farmitalia Carlo Erba S.P.A.||Device for coupling a small tube to an apparatus adapted for fitting a syringe to a drug holding bottle|
|US4854480 *||4 Jan 1988||8 Aug 1989||Shindo Robert S||Long range trigger-actuated squirt gun|
|US4857055 *||14 Apr 1987||15 Aug 1989||Wang Paul Y||Compression device enabling flexible solution containers to produce constant delivery rate|
|US4863454 *||6 Nov 1987||5 Sep 1989||Labove Larry D||Dual bag intravenous preparation system|
|US4867208 *||4 Feb 1988||19 Sep 1989||Fitzgerald Robert M||Apparatus for storing and dispensing fluid under pressure|
|US4953753 *||10 Jun 1988||4 Sep 1990||The Norman Company||Fluid dispensing apparatus with prestressed bladder|
|US4955512 *||23 Jan 1989||11 Sep 1990||Splicerite Limited||Liquid container and dispenser for controlled liquid dispensation|
|US5011477 *||21 Apr 1989||30 Apr 1991||Baxter International Inc.||Continuous/bolus infusor|
|US5061243 *||8 Feb 1989||29 Oct 1991||Baxter International Inc.||System and apparatus for the patient-controlled delivery of a beneficial agent, and set therefor|
|US5080652 *||12 Mar 1990||14 Jan 1992||Block Medical, Inc.||Infusion apparatus|
|US5098385 *||26 Apr 1990||24 Mar 1992||Baxter International Inc.||Two-way valve for infusion devices|
|US5105983 *||31 Oct 1989||21 Apr 1992||Block Medical, Inc.||Infusion apparatus|
|US5135497 *||8 Jul 1991||4 Aug 1992||Baxter International Inc.||Large volume pressurized fluid dispenser|
|US5137175 *||28 Feb 1990||11 Aug 1992||Gmi Engineering & Management Institute||Fluid storing and dispensing|
|US5306257 *||4 May 1992||26 Apr 1994||Prime Medical Products, Inc.||Drug infuser|
|US5346476 *||29 Apr 1992||13 Sep 1994||Edward E. Elson||Fluid delivery system|
|US5529525 *||5 Oct 1994||25 Jun 1996||Deal; Jeffry T.||Water bomb - mounted water gun|
|US5531626 *||8 Jul 1994||2 Jul 1996||Deal; Jeffry T.||Toy water bomb device|
|US5531627 *||15 Feb 1995||2 Jul 1996||Deal; Jeffry T.||Cartridge-type water bomb water gun conversion device|
|US5538457 *||5 Oct 1994||23 Jul 1996||Deal; Jeffry T.||Water gun with turreted multiple water bomb launchers|
|US5758800 *||28 Jun 1996||2 Jun 1998||D'andrade; Bruce M.||Bladder for water gun|
|US5799827 *||28 Jun 1996||1 Sep 1998||D'andrade; Bruce M.||Bladder water gun|
|US5906295 *||31 Mar 1998||25 May 1999||D'andrade; Bruce M.||Bladder for water gun|
|US6012609 *||8 Feb 1999||11 Jan 2000||Larami Limited||Bladder water gun|
|US6158619 *||5 Jan 1999||12 Dec 2000||D'andrade Bruce M.||Bladder gun with body mounted nozzle and quick-charged system|
|US6193107||23 Nov 1999||27 Feb 2001||Larami Limited||Bladder water gun|
|US6257448||5 Jan 1999||10 Jul 2001||D'andrade Bruce M.||Backpack externally chargeable bladder gun assembly|
|US6739782 *||17 Mar 2003||25 May 2004||Rehco, L.L.C.||Oral cleaning device with internal water bladder|
|US7361168||4 Aug 2004||22 Apr 2008||Acclarent, Inc.||Implantable device and methods for delivering drugs and other substances to treat sinusitis and other disorders|
|US7410480||23 Sep 2005||12 Aug 2008||Acclarent, Inc.||Devices and methods for delivering therapeutic substances for the treatment of sinusitis and other disorders|
|US7419497||4 Oct 2006||2 Sep 2008||Acclarent, Inc.||Methods for treating ethmoid disease|
|US7547323||29 Aug 2006||16 Jun 2009||Sinexus, Inc.||Stent for irrigation and delivery of medication|
|US7720521||26 Apr 2005||18 May 2010||Acclarent, Inc.||Methods and devices for performing procedures within the ear, nose, throat and paranasal sinuses|
|US7785315||12 Dec 2007||31 Aug 2010||Acclarent, Inc.||Methods for irrigation of ethmoid air cells and treatment of ethmoid disease|
|US8080000||30 Oct 2007||20 Dec 2011||Acclarent, Inc.||Methods and apparatus for treating disorders of the ear nose and throat|
|US8088101||26 Oct 2007||3 Jan 2012||Acclarent, Inc.||Devices, systems and methods for treating disorders of the ear, nose and throat|
|US8090433||30 Oct 2007||3 Jan 2012||Acclarent, Inc.||Methods and apparatus for treating disorders of the ear nose and throat|
|US8100933||8 May 2008||24 Jan 2012||Acclarent, Inc.||Method for treating obstructed paranasal frontal sinuses|
|US8114062||1 Oct 2009||14 Feb 2012||Acclarent, Inc.||Devices and methods for delivering therapeutic substances for the treatment of sinusitis and other disorders|
|US8114113||4 Oct 2005||14 Feb 2012||Acclarent, Inc.||Multi-conduit balloon catheter|
|US8118757||30 Apr 2007||21 Feb 2012||Acclarent, Inc.||Methods and devices for ostium measurement|
|US8123722||29 Oct 2007||28 Feb 2012||Acclarent, Inc.||Devices, systems and methods for treating disorders of the ear, nose and throat|
|US8142422||4 Mar 2008||27 Mar 2012||Acclarent, Inc.||Devices, systems and methods for diagnosing and treating sinusitis and other disorders of the ears, nose and/or throat|
|US8146400||31 Jul 2007||3 Apr 2012||Acclarent, Inc.||Endoscopic methods and devices for transnasal procedures|
|US8172828||30 Oct 2007||8 May 2012||Acclarent, Inc.||Apparatus and methods for dilating and modifying ostia of paranasal sinuses and other intranasal or paranasal structures|
|US8182432||10 Mar 2008||22 May 2012||Acclarent, Inc.||Corewire design and construction for medical devices|
|US8190389||17 May 2006||29 May 2012||Acclarent, Inc.||Adapter for attaching electromagnetic image guidance components to a medical device|
|US8277503||7 May 2009||2 Oct 2012||Intersect Ent, Inc.||Stent for irrigation and delivery of medication|
|US8277504||7 May 2009||2 Oct 2012||Intersect Ent, Inc.||Stent for irrigation and delivery of medication|
|US8316897||25 Jan 2010||27 Nov 2012||Mattel, Inc.||Water gun assembly|
|US8317816||30 Sep 2002||27 Nov 2012||Acclarent, Inc.||Balloon catheters and methods for treating paranasal sinuses|
|US8388642||29 Aug 2008||5 Mar 2013||Acclarent, Inc.||Implantable devices and methods for treating sinusitis and other disorders|
|US8414473||16 Sep 2009||9 Apr 2013||Acclarent, Inc.||Methods and apparatus for treating disorders of the ear nose and throat|
|US8425457||29 Dec 2009||23 Apr 2013||Acclarent, Inc.||Devices, systems and methods for diagnosing and treating sinusitus and other disorder of the ears, nose and/or throat|
|US8435290||24 Mar 2010||7 May 2013||Acclarent, Inc.||System and method for treatment of non-ventilating middle ear by providing a gas pathway through the nasopharynx|
|US8439687||29 Dec 2006||14 May 2013||Acclarent, Inc.||Apparatus and method for simulated insertion and positioning of guidewares and other interventional devices|
|US8485199||8 May 2007||16 Jul 2013||Acclarent, Inc.||Methods and devices for protecting nasal turbinate during surgery|
|US8702626||29 Dec 2006||22 Apr 2014||Acclarent, Inc.||Guidewires for performing image guided procedures|
|US8715169||30 Oct 2007||6 May 2014||Acclarent, Inc.||Devices, systems and methods useable for treating sinusitis|
|US8721591||23 Jan 2012||13 May 2014||Acclarent, Inc.||Apparatus and methods for dilating and modifying ostia of paranasal sinuses and other intranasal or paranasal structures|
|US8740929||6 Feb 2002||3 Jun 2014||Acclarent, Inc.||Spacing device for releasing active substances in the paranasal sinus|
|US8746357||19 Oct 2007||10 Jun 2014||Ada Technologies, Inc.||Fine water mist multiple orientation discharge fire extinguisher|
|US8747389||24 Apr 2007||10 Jun 2014||Acclarent, Inc.||Systems for treating disorders of the ear, nose and throat|
|US8764709||30 Jun 2010||1 Jul 2014||Acclarent, Inc.||Devices, systems and methods for treating disorders of the ear, nose and throat|
|US8764726||18 Aug 2009||1 Jul 2014||Acclarent, Inc.||Devices, systems and methods useable for treating sinusitis|
|US8764729||22 Dec 2008||1 Jul 2014||Acclarent, Inc.||Frontal sinus spacer|
|US8764786||9 Oct 2012||1 Jul 2014||Acclarent, Inc.||Balloon catheters and methods for treating paranasal sinuses|
|US8777926||15 Mar 2013||15 Jul 2014||Acclarent, Inc.||Apparatus and methods for dilating and modifying ostia of paranasal sinuses and other intranasel or paranasal structures|
|US8828041||18 Mar 2010||9 Sep 2014||Acclarent, Inc.||Devices, systems and methods useable for treating sinusitis|
|US8852143||7 Apr 2010||7 Oct 2014||Acclarent, Inc.||Devices, systems and methods for treating disorders of the ear, nose and throat|
|US8858586||18 Jan 2007||14 Oct 2014||Acclarent, Inc.||Methods for enlarging ostia of paranasal sinuses|
|US8864787||9 Apr 2008||21 Oct 2014||Acclarent, Inc.||Ethmoidotomy system and implantable spacer devices having therapeutic substance delivery capability for treatment of paranasal sinusitis|
|US8870893||29 Apr 2010||28 Oct 2014||Acclarent, Inc.||Devices, systems and methods for diagnosing and treating sinusitis and other disorders of the ears, nose and/or throat|
|US8894614||16 Feb 2006||25 Nov 2014||Acclarent, Inc.||Devices, systems and methods useable for treating frontal sinusitis|
|US8905922||26 Mar 2012||9 Dec 2014||Acclarent, Inc.||Devices, systems and methods for diagnosing and treating sinusitis and other disorders of the ears, nose and/or throat|
|US8932276||16 May 2007||13 Jan 2015||Acclarent, Inc.||Shapeable guide catheters and related methods|
|US8945088||28 Apr 2010||3 Feb 2015||Acclarent, Inc.||Apparatus and methods for dilating and modifying ostia of paranasal sinuses and other intranasal or paranasal structures|
|US8951225||18 May 2006||10 Feb 2015||Acclarent, Inc.||Catheters with non-removable guide members useable for treatment of sinusitis|
|US8961398||31 Oct 2007||24 Feb 2015||Acclarent, Inc.||Methods and apparatus for treating disorders of the ear, nose and throat|
|US8961495||29 Oct 2007||24 Feb 2015||Acclarent, Inc.||Devices, systems and methods for treating disorders of the ear, nose and throat|
|US8968269||18 Jan 2012||3 Mar 2015||Acclarent, Inc.||Multi-conduit balloon catheter|
|US8979888||30 Jul 2009||17 Mar 2015||Acclarent, Inc.||Paranasal ostium finder devices and methods|
|US9039657||3 Sep 2009||26 May 2015||Acclarent, Inc.||Implantable devices and methods for delivering drugs and other substances to treat sinusitis and other disorders|
|US9039680||21 Apr 2008||26 May 2015||Acclarent, Inc.||Implantable devices and methods for delivering drugs and other substances to treat sinusitis and other disorders|
|US9050440||22 Sep 2006||9 Jun 2015||Acclarent, Inc.||Multi-conduit balloon catheter|
|US9055965||22 Mar 2010||16 Jun 2015||Acclarent, Inc.||Devices, systems and methods useable for treating sinusitis|
|US9072626||6 May 2013||7 Jul 2015||Acclarent, Inc.||System and method for treatment of non-ventilating middle ear by providing a gas pathway through the nasopharynx|
|US9084876||15 Mar 2013||21 Jul 2015||Acclarent, Inc.||Implantable devices and methods for delivering drugs and other substances to treat sinusitis and other disorders|
|US9089258||15 Mar 2007||28 Jul 2015||Acclarent, Inc.||Endoscopic methods and devices for transnasal procedures|
|US9101384||16 Jan 2009||11 Aug 2015||Acclarent, Inc.||Devices, systems and methods for diagnosing and treating sinusitis and other disorders of the ears, Nose and/or throat|
|US9107574||8 Dec 2011||18 Aug 2015||Acclarent, Inc.||Endoscopic methods and devices for transnasal procedures|
|US9155492||24 Sep 2010||13 Oct 2015||Acclarent, Inc.||Sinus illumination lightwire device|
|US9167961||31 Oct 2007||27 Oct 2015||Acclarent, Inc.||Methods and apparatus for treating disorders of the ear nose and throat|
|US9179823||5 Jun 2009||10 Nov 2015||Acclarent, Inc.||Methods and devices for facilitating visualization in a surgical environment|
|US9198736||19 Apr 2012||1 Dec 2015||Acclarent, Inc.||Adapter for attaching electromagnetic image guidance components to a medical device|
|US9220879||30 Apr 2014||29 Dec 2015||Acclarent, Inc.||Devices, systems and methods useable for treating sinusitis|
|US9241834||21 Mar 2014||26 Jan 2016||Acclarent, Inc.||Devices, systems and methods for treating disorders of the ear, nose and throat|
|US9265407||31 Jul 2007||23 Feb 2016||Acclarent, Inc.||Endoscopic methods and devices for transnasal procedures|
|US9308361||4 Mar 2013||12 Apr 2016||Acclarent, Inc.||Implantable devices and methods for treating sinusitis and other disorders|
|US9351750||16 Dec 2009||31 May 2016||Acclarent, Inc.||Devices and methods for treating maxillary sinus disease|
|US9370649||5 Feb 2015||21 Jun 2016||Acclarent, Inc.||Devices, systems and methods useable for treating sinusitis|
|US9399121||1 Jul 2009||26 Jul 2016||Acclarent, Inc.||Systems and methods for transnasal dilation of passageways in the ear, nose or throat|
|US9433437||15 Mar 2013||6 Sep 2016||Acclarent, Inc.||Apparatus and method for treatment of ethmoid sinusitis|
|US9457175||4 Sep 2015||4 Oct 2016||Acclarent, Inc.||Balloon catheters and methods for treating paranasal sinuses|
|US9463068||18 Jun 2013||11 Oct 2016||Acclarent, Inc.||Methods and devices for protecting nasal turbinates|
|US9468362||19 Apr 2012||18 Oct 2016||Acclarent, Inc.||Endoscopic methods and devices for transnasal procedures|
|US20040206771 *||18 Apr 2003||21 Oct 2004||Eric Junkel||Water toy with two port elastic fluid bladder|
|US20060081645 *||13 Oct 2005||20 Apr 2006||Eric Junkel||Water toy with two port elastic fluid bladder|
|US20060097004 *||13 Oct 2005||11 May 2006||Eric Junkel||Water toy with two port elastic fluid bladder|
|US20080097354 *||29 Aug 2006||24 Apr 2008||Francois Lavigne||Stent for irrigation and delivery of medication|
|US20090275882 *||7 May 2009||5 Nov 2009||Francois Lavigne||Stent for irrigation and delivery of medication|
|US20090275903 *||7 May 2009||5 Nov 2009||Francois Lavigne||Stent for irrigation and delivery of medication|
|US20100198247 *||7 Apr 2010||5 Aug 2010||Acclarent, Inc.||Devices, Systems and Methods for Treating Disorders of the Ear, Nose and Throat|
|US20100269953 *||25 Jan 2010||28 Oct 2010||Mattel, Inc.||Water Gun Assembly|
|US20150151857 *||3 Jul 2014||4 Jun 2015||Deka Products Limited Partnership||Apparatus, System and Method for Fluid Delivery|
|US20150157537 *||3 Jul 2014||11 Jun 2015||Richard J. Lanigan||Apparatus, System and Method for Fluid Delivery|
|USRE35187 *||4 Sep 1992||26 Mar 1996||Gortz; Norman||Fluid dispensing apparatus with prestressed bladder|
|DE2420978A1 *||30 Apr 1974||20 Nov 1975||Alza Corp||Elastische blase zum speichern und abgeben unter druck einer fluessigkeit sowie vorrichtung mit einer solchen blase|
|EP0032792A2 *||8 Jan 1981||29 Jul 1981||Alza Corporation||Medical infusor|
|EP0032792A3 *||8 Jan 1981||2 Dec 1981||Alza Corporation||Medical infusor|
|EP0172586A1 *||8 Jan 1981||26 Feb 1986||Alza Corporation||Medical infusor|
|EP0211850A1 *||23 Dec 1985||4 Mar 1987||Baxter Travenol Lab||Infusor having a distal flow regulator.|
|EP0211850B1 *||23 Dec 1985||20 Feb 1991||BAXTER INTERNATIONAL INC. (a Delaware corporation)||Infusor having a distal flow regulator|
|EP2818197A1 *||30 Jun 2014||31 Dec 2014||Raffaele Longo||Catheter|
|WO1988000841A1 *||10 Aug 1987||11 Feb 1988||Edward John Keogh||Expansible chamber drug infuser system|
|WO1991016101A1 *||27 Feb 1991||31 Oct 1991||Baxter International Inc.||Two-way valve for infusion devices|
|WO1998000214A1||27 Jun 1997||8 Jan 1998||Andrade Bruce M D||Bladder water gun, improved bladder and nozzle|
|U.S. Classification||141/329, 128/DIG.120, 239/323, 141/387, 604/132, 222/386.5, 141/383, 222/323, 141/382, 600/576, 222/564|
|International Classification||A61M5/00, A61M5/168, A61M5/152, A61M5/162|
|Cooperative Classification||A61M5/162, A61M5/00, A61M5/152, Y10S128/12|
|European Classification||A61M5/00, A61M5/162, A61M5/152|