US3434615A - Centrifuge bottle and closure therefor - Google Patents

Centrifuge bottle and closure therefor Download PDF

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Publication number
US3434615A
US3434615A US666710A US3434615DA US3434615A US 3434615 A US3434615 A US 3434615A US 666710 A US666710 A US 666710A US 3434615D A US3434615D A US 3434615DA US 3434615 A US3434615 A US 3434615A
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United States
Prior art keywords
bottle
closure
mouth
stopper
centrifuge bottle
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
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US666710A
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Anthony J Barletta
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Thermo IEC Inc
INT EQUIPMENT CO
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INT EQUIPMENT CO
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    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5021Test tubes specially adapted for centrifugation purposes
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
    • B01L3/5082Test tubes per se
    • B01L3/50825Closing or opening means, corks, bungs

Definitions

  • Plastic centrifuge bottles are widely used and are satisfactory to the extent they can be sealed against leakage while their contents are being centrifuged.
  • One particular problem is that even when the upper part of the bottle is rigidly held in a jacket and the closure seated by a cap threaded on the jacket in accordance with Patent No. 3,265,296, for example, the sealing means sometimes fail.
  • the particular objective of the present invention is to provide a closure-bottle construction providing a seal of substantially increased effectiveness.
  • this objective is attained by tapering the upper end portion of the inner surface of the bottle outwardly to the mouth thereof and by providing a closure in the form of a stopper tapering inwardly towards its mouth-entering end.
  • the closure has a plurality of annular grooves each supporting a sealing ring, the sealing rings being brought into effective sealing relationship with the tapered portion of the bottle by closure attaching means attached to the bottle.
  • FIGURE 1 is a perspective view of a centrifuge bottle in accordance with the invention, and the bottle-closing means therefor, the bottle-closing means being shown as detached from the bottle and its parts separated from each other.
  • FIGURE 2 is a vertically sectioned view on an increase in scale of the closure and of the upper part of the bottle, the closure being partly entered into the mouth of the bottle, and
  • FIGURE 3 is a view on the scale of FIGURE 2 but with the closure so clamped to the bottle as to render its sealing rings effective.
  • a centrifuge bottle is generally indicated at 5 and is shown 5 having a neck 6 provided with external threads 7 and establishing a shoulder 8.
  • the bottle 5 has a relatively flexible wall structure as it is molded from a suitable plastic such, for example, as polyethylene, polypropylene, or a polycarbonate.
  • a suitable plastic such as polyethylene, polypropylene, or a polycarbonate.
  • the inner surface of the neck 6 is tapered outwardly as at 6A to the mouth 9 of the bottle 5.
  • a reinforcing jacket generally indicated at 10 and preferably of metal, has a neck 11 formed with internal threads 12 and external threads 13, a portion 14 extending below the bottle shoulder 8 and an internal, intermediate shoulder 15 engagealble therewith.
  • the internal threads 12 enable the jacket 10 to be threaded onto the bottle 5 until its shoulder 15 engages the shoulder 8, the
  • a closure generally indicated at 16 and made of a suitable auto-claveable and clinically inert plastic, Delvin, a product of E. I. du Pont de Nemours: & Company, Inc., for example, includes a stopper portion 17 that is tapered inwardly towards its bottle-entering end.
  • the stopper portion 17 has annular grooves 18 and 19 for the compressible sealing rings 20 and 21, respectively.
  • the closure 16 also has a marginal flange 22 of a diameter greater than the inside diameter of the jacket neck 11 but less than the inside diameter of the generally indicated cap 23 which is interiorly threaded as at 24 for attachment to the jacket neck .11 and has an annular internal flange 25 engagea-ble with the closure flange 22 so that, as the cap 23 is threaded onto the jacket neck 11, the closure 16 will be securely seated.
  • the stopper portion 17 of the closure 16 is so dimensioned that its bottle-entering end is a free fit in the portion 6A of the bottle 5 and that when it has been advanced therein to an extent suitably compressing the sealing rings 20 and 21, the stopper portion 17 does not contact the portion 6A and the flange 22 does not engage the bottle mouth 9.
  • the portion 6A and the portion 17 taper to the same degree, best results being obtained with a taper that is approximately 3 from the vertical.
  • the sealing rings 20 and 21 are compressed. approximately to the same extent with the ring 20 backing the sealing ring 21 and with the sealing ring 21 ensuring that the full pressure on it is not transferred to the sealing ring 20, even should leakage occur.
  • a plastic centrifuge bottle a portion of the inner surface of the bottle tapering outwardly to the mouth thereof, a closure in the form of a stopper tapering inwardly towards its mouth-entering end and having a plurality of grooves, 21 compressible sealing ring in each groove, and means to clamp said closure to the bottle, the axial extents of said bottle portion and of said stopper being such that said rings are compressed against said bottle portion when the closure is so clamped and the dimensions of the stopper being such that it is then substantially without contact with said bottle portion.

Description

March 25, 1969 A. J. BARLETTA 3,434,615
CENTR IFUGE BOTTLE AND CLOSURE THEREFOR Filed Sept. 11. 1967 Shee t of 2 FIG] fi .r s I "I INVENTPOR ANTHONY J. BARLETTA BY, a
ATTORN EY March 25, 1969 A. J. BARLETTA 3,434,615
CENTRIFUGE BOTTLE AND CLOSURE THEREFOR Filed Sept. 11, 1967 Sheet 2 of 2 /6 E5 90 El 9 9 FIGB E3 "8:? he a I; I 8 6A I I? 1 I i i I? J" INVENTOR ANTHONY J. BARLETTA ATTORNEY United States Patent US. Cl. 21547 6 Claims ABSTRACT OF THE DISCLOSURE Plastic centrifuge bottle having a portion of its wall tapering outwardly to the mouth, a closure tapering inwardly towards its mouth-entering end and carrying a plurality of sealing rings, and means to attach the closure to the bottle and to render the seals eflective.
Plastic centrifuge bottles are widely used and are satisfactory to the extent they can be sealed against leakage while their contents are being centrifuged. One particular problem is that even when the upper part of the bottle is rigidly held in a jacket and the closure seated by a cap threaded on the jacket in accordance with Patent No. 3,265,296, for example, the sealing means sometimes fail.
The particular objective of the present invention is to provide a closure-bottle construction providing a seal of substantially increased effectiveness. In accordance with the invention, this objective is attained by tapering the upper end portion of the inner surface of the bottle outwardly to the mouth thereof and by providing a closure in the form of a stopper tapering inwardly towards its mouth-entering end. The closure has a plurality of annular grooves each supporting a sealing ring, the sealing rings being brought into effective sealing relationship with the tapered portion of the bottle by closure attaching means attached to the bottle.
In the accompanying drawings, there is shown an illustrative embodiment of the invention from which these and other of its objectives, novel features, and advantages will be readily apparent.
In the drawings:
FIGURE 1 is a perspective view of a centrifuge bottle in accordance with the invention, and the bottle-closing means therefor, the bottle-closing means being shown as detached from the bottle and its parts separated from each other.
FIGURE 2 is a vertically sectioned view on an increase in scale of the closure and of the upper part of the bottle, the closure being partly entered into the mouth of the bottle, and
FIGURE 3 is a view on the scale of FIGURE 2 but with the closure so clamped to the bottle as to render its sealing rings effective.
A centrifuge bottle is generally indicated at 5 and is shown 5 having a neck 6 provided with external threads 7 and establishing a shoulder 8. The bottle 5 has a relatively flexible wall structure as it is molded from a suitable plastic such, for example, as polyethylene, polypropylene, or a polycarbonate. As may best be seen in FIG- URES 2 and 3 the inner surface of the neck 6 is tapered outwardly as at 6A to the mouth 9 of the bottle 5.
A reinforcing jacket, generally indicated at 10 and preferably of metal, has a neck 11 formed with internal threads 12 and external threads 13, a portion 14 extending below the bottle shoulder 8 and an internal, intermediate shoulder 15 engagealble therewith. The internal threads 12 enable the jacket 10 to be threaded onto the bottle 5 until its shoulder 15 engages the shoulder 8, the
37,434,615 Patented Mar. 25, 1969 upper end of the jacket neck 11 then being below the mouth 9 of the bottle.
A closure, generally indicated at 16 and made of a suitable auto-claveable and clinically inert plastic, Delvin, a product of E. I. du Pont de Nemours: & Company, Inc., for example, includes a stopper portion 17 that is tapered inwardly towards its bottle-entering end. The stopper portion 17 has annular grooves 18 and 19 for the compressible sealing rings 20 and 21, respectively. The closure 16 also has a marginal flange 22 of a diameter greater than the inside diameter of the jacket neck 11 but less than the inside diameter of the generally indicated cap 23 which is interiorly threaded as at 24 for attachment to the jacket neck .11 and has an annular internal flange 25 engagea-ble with the closure flange 22 so that, as the cap 23 is threaded onto the jacket neck 11, the closure 16 will be securely seated.
It will be noted that the stopper portion 17 of the closure 16 is so dimensioned that its bottle-entering end is a free fit in the portion 6A of the bottle 5 and that when it has been advanced therein to an extent suitably compressing the sealing rings 20 and 21, the stopper portion 17 does not contact the portion 6A and the flange 22 does not engage the bottle mouth 9. Desirably, 'both the portion 6A and the portion 17 taper to the same degree, best results being obtained with a taper that is approximately 3 from the vertical.
With the construction provided by the invention the sealing rings 20 and 21 are compressed. approximately to the same extent with the ring 20 backing the sealing ring 21 and with the sealing ring 21 ensuring that the full pressure on it is not transferred to the sealing ring 20, even should leakage occur.
I claim:
1. In combination, a plastic centrifuge bottle, a portion of the inner surface of the bottle tapering outwardly to the mouth thereof, a closure in the form of a stopper tapering inwardly towards its mouth-entering end and having a plurality of grooves, 21 compressible sealing ring in each groove, and means to clamp said closure to the bottle, the axial extents of said bottle portion and of said stopper being such that said rings are compressed against said bottle portion when the closure is so clamped and the dimensions of the stopper being such that it is then substantially without contact with said bottle portion.
2. The combination of claim 1 in which the bottle has threads adjacent its mouth and the sealing rings are substantially in the zone of the threads.
3. The combination of claim 1 in which the taper of the bottle portion is approximately 3 4. The combination of claim 1 in which the taper of the bottle portion and of the stopper is approximately the same.
5. The combination of claim 1 in which the taper of the bottle portion and of the stopper is approximately 3.
6. The combination of claim 1 in which the closure includes a marginal flange dimensioned to overlie the mouth of the bottle.
References Cited UNITED STATES PATENTS 2,848,130 8/1958 Jesnig 215-47 XR 2,330,282 7/1967 Visser et al 215-47 XR 3,366,320 1/1968 Cho 233-46 GEORGE T. HALL, Primary Examiner.
US. Cl. X.R. 215-97; 233-26
US666710A 1967-09-11 1967-09-11 Centrifuge bottle and closure therefor Expired - Lifetime US3434615A (en)

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Cited By (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3899096A (en) * 1972-03-07 1975-08-12 Illinois Tool Works Reformed plastic article and method of manufacture
US3938735A (en) * 1975-03-13 1976-02-17 Beckman Instruments, Inc. Capping assembly for thin all centrifuge tubes
US3998383A (en) * 1975-07-16 1976-12-21 E. I. Du Pont De Nemours And Company Gradient separation apparatus
US4034883A (en) * 1976-08-03 1977-07-12 Wojcik Walter J Closure lid for home canning jar
US4076170A (en) * 1977-04-18 1978-02-28 Beckman Instruments, Inc. Tube cap assembly for preparative centrifuge rotors
US4080175A (en) * 1977-04-19 1978-03-21 Beckman Instruments, Inc. Internally activated sealing centrifuge test tube cap assembly
US4166573A (en) * 1977-12-01 1979-09-04 E. I. Du Pont De Nemours And Company Centrifuge tube enclosure
US4222513A (en) * 1978-12-12 1980-09-16 E. I. Du Pont De Nemours And Company Centrifuge tube seal
US4537320A (en) * 1983-10-27 1985-08-27 Nielsen Steven T Centrifuge tube having removable crown and swage fitting
US4591061A (en) * 1981-08-05 1986-05-27 Birkbeck College Safety container for waste organic solvents
DE8700742U1 (en) * 1987-01-16 1987-05-14 Herolab Gmbh Laborgeraete, 6837 St. Leon-Rot, De
US4750525A (en) * 1985-04-15 1988-06-14 Vaughan Daniel J End closure for flexible plastic tubes
US4902270A (en) * 1988-10-03 1990-02-20 Nalge Company Centrifuge tube
US5020679A (en) * 1988-06-08 1991-06-04 Alberto Signorini Nursing apparatus
US5109997A (en) * 1991-06-21 1992-05-05 Phillips Edwin D Expandable stopper
US5127895A (en) * 1990-03-30 1992-07-07 Beckman Instruments, Inc. Self-seal centrifuge tube
US5158204A (en) * 1992-02-06 1992-10-27 Air Products And Chemicals, Inc. Containment and diversion cap for gas cylinders
US5174460A (en) * 1992-02-26 1992-12-29 Sunbeam Plastics Corporation Dual seal closure-adaptor
US5213223A (en) * 1992-03-23 1993-05-25 Sunbeam Plastics Corporation Child resistant closure-adaptor
WO1998005426A2 (en) * 1996-08-02 1998-02-12 C.A. Greiner & Söhne Gesellschaft Mbh Sealing device, separating device and collecting receptacle for a collector device
US20040108294A1 (en) * 2002-08-12 2004-06-10 Bloom Kenneth S. Plastic closure, closure and container package, and method of manufacture
US20040193080A1 (en) * 2003-03-24 2004-09-30 Health Devices Corporation Vibrator assembly with adaptor coupling
FR2859709A1 (en) * 2003-09-12 2005-03-18 Tournaire Sa Sleeve fixing device for use in e.g. perfume container, has lamellas, ring and seam to stop rotation and longitudinal movement of crown around neck, and two clipping rings for locking sleeve on crown
US20050173371A1 (en) * 2002-05-08 2005-08-11 Bruno Zeni Composite stopper made synthetic materials
US20060091099A1 (en) * 2004-11-03 2006-05-04 Klepac Gary W Leak resistant container and method of using same
US20060102584A1 (en) * 2004-11-18 2006-05-18 Craig Wellman Two-part closure for a container
DE102004062233A1 (en) * 2004-12-23 2006-07-13 Kendro Laboratory Products Gmbh Centrifuge adapter and cap
US20070062900A1 (en) * 2005-09-20 2007-03-22 Manera David A Moisture-tight safety closure and container having a flexible neck finish
WO2009026436A1 (en) 2007-08-21 2009-02-26 Nalge Nunc International Corporation Centrifuge bottle closure and assembly thereof
US7611026B1 (en) 2002-08-12 2009-11-03 Rexam Closure Systems Inc. Tamper-evident closure having a sealing disk and package for high-temperature applications
US20100258698A1 (en) * 2009-04-14 2010-10-14 Wunderwall, LLC Cup for holding bottles in a bottle rack
WO2012130016A1 (en) * 2011-03-31 2012-10-04 Chen Yuxiang Seal cover with flexible interface
US20160158744A1 (en) * 2014-12-03 2016-06-09 Fiberlite Centrifuge, Llc Centrifuge Sample Container And Closure Therefor
USD777342S1 (en) * 2014-12-03 2017-01-24 Fiberlite Centrifuge, Llc Centrifuge bottle handle
USD777941S1 (en) * 2015-07-17 2017-01-31 Fiberlite Centrifuge, Llc Centrifuge bottle
US10112199B2 (en) 2014-12-03 2018-10-30 Fiberlite Centrifuge, Llc Centrifuge sample container and closure therefore
US10220983B1 (en) * 2015-07-27 2019-03-05 James R. Gilliam Threaded bottle ring and method of fabrication and attachment
USD908001S1 (en) * 2018-09-04 2021-01-19 Jean-Pierre Pinard Cap for a bottle
US11090646B2 (en) 2017-07-27 2021-08-17 Biomerieux, Inc. Isolation tube
US11440712B2 (en) * 2018-12-27 2022-09-13 Indrio Brands, Llc Beverage container system and components

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2330282A (en) * 1940-07-31 1943-09-28 Monsanto Chemicals Manufacture of continuous sheets or webs of plastic material
US2848130A (en) * 1953-10-07 1958-08-19 Duo Vent Vacuum Closure Compan Pressure resistant closures
US3366320A (en) * 1965-07-21 1968-01-30 Atomic Energy Commission Usa Centrifuge sample holder

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2330282A (en) * 1940-07-31 1943-09-28 Monsanto Chemicals Manufacture of continuous sheets or webs of plastic material
US2848130A (en) * 1953-10-07 1958-08-19 Duo Vent Vacuum Closure Compan Pressure resistant closures
US3366320A (en) * 1965-07-21 1968-01-30 Atomic Energy Commission Usa Centrifuge sample holder

Cited By (66)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3899096A (en) * 1972-03-07 1975-08-12 Illinois Tool Works Reformed plastic article and method of manufacture
US3938735A (en) * 1975-03-13 1976-02-17 Beckman Instruments, Inc. Capping assembly for thin all centrifuge tubes
US3998383A (en) * 1975-07-16 1976-12-21 E. I. Du Pont De Nemours And Company Gradient separation apparatus
US4034883A (en) * 1976-08-03 1977-07-12 Wojcik Walter J Closure lid for home canning jar
US4076170A (en) * 1977-04-18 1978-02-28 Beckman Instruments, Inc. Tube cap assembly for preparative centrifuge rotors
US4080175A (en) * 1977-04-19 1978-03-21 Beckman Instruments, Inc. Internally activated sealing centrifuge test tube cap assembly
US4166573A (en) * 1977-12-01 1979-09-04 E. I. Du Pont De Nemours And Company Centrifuge tube enclosure
US4222513A (en) * 1978-12-12 1980-09-16 E. I. Du Pont De Nemours And Company Centrifuge tube seal
US4591061A (en) * 1981-08-05 1986-05-27 Birkbeck College Safety container for waste organic solvents
US4537320A (en) * 1983-10-27 1985-08-27 Nielsen Steven T Centrifuge tube having removable crown and swage fitting
US4750525A (en) * 1985-04-15 1988-06-14 Vaughan Daniel J End closure for flexible plastic tubes
DE8700742U1 (en) * 1987-01-16 1987-05-14 Herolab Gmbh Laborgeraete, 6837 St. Leon-Rot, De
US5020679A (en) * 1988-06-08 1991-06-04 Alberto Signorini Nursing apparatus
US4902270A (en) * 1988-10-03 1990-02-20 Nalge Company Centrifuge tube
US5127895A (en) * 1990-03-30 1992-07-07 Beckman Instruments, Inc. Self-seal centrifuge tube
US5109997A (en) * 1991-06-21 1992-05-05 Phillips Edwin D Expandable stopper
US5158204A (en) * 1992-02-06 1992-10-27 Air Products And Chemicals, Inc. Containment and diversion cap for gas cylinders
US5174460A (en) * 1992-02-26 1992-12-29 Sunbeam Plastics Corporation Dual seal closure-adaptor
US5213223A (en) * 1992-03-23 1993-05-25 Sunbeam Plastics Corporation Child resistant closure-adaptor
WO1998005426A2 (en) * 1996-08-02 1998-02-12 C.A. Greiner & Söhne Gesellschaft Mbh Sealing device, separating device and collecting receptacle for a collector device
WO1998005426A3 (en) * 1996-08-02 1998-05-07 Greiner & Soehne C A Sealing device, separating device and collecting receptacle for a collector device
US6277331B1 (en) 1996-08-02 2001-08-21 C. A. Greiner & Söhne Gesellschaft mbH Holding device for body fluids and tissues
US20050173371A1 (en) * 2002-05-08 2005-08-11 Bruno Zeni Composite stopper made synthetic materials
US7611026B1 (en) 2002-08-12 2009-11-03 Rexam Closure Systems Inc. Tamper-evident closure having a sealing disk and package for high-temperature applications
US20040108294A1 (en) * 2002-08-12 2004-06-10 Bloom Kenneth S. Plastic closure, closure and container package, and method of manufacture
US7147118B2 (en) 2002-08-12 2006-12-12 Owens-Illinois Closure Inc. Plastic closure, closure and container package, and method of manufacture
US6874647B2 (en) * 2002-08-12 2005-04-05 Owens-Illinois Closure Inc. Plastic closure, closure and container package, and method of manufacture
US20050098529A1 (en) * 2002-08-12 2005-05-12 Bloom Kenneth S. Plastic closure, closure and container package, and method of manufacture
US20040193080A1 (en) * 2003-03-24 2004-09-30 Health Devices Corporation Vibrator assembly with adaptor coupling
WO2005026008A1 (en) * 2003-09-12 2005-03-24 Tournaire S.A. Fixing system for a socket mounted on a finally-shaped container
FR2859709A1 (en) * 2003-09-12 2005-03-18 Tournaire Sa Sleeve fixing device for use in e.g. perfume container, has lamellas, ring and seam to stop rotation and longitudinal movement of crown around neck, and two clipping rings for locking sleeve on crown
US20060091099A1 (en) * 2004-11-03 2006-05-04 Klepac Gary W Leak resistant container and method of using same
US20060102584A1 (en) * 2004-11-18 2006-05-18 Craig Wellman Two-part closure for a container
US8132685B2 (en) * 2004-11-18 2012-03-13 Pathtainer Systems International Pty. Ltd. Two-part closure for a container
DE102004062233A1 (en) * 2004-12-23 2006-07-13 Kendro Laboratory Products Gmbh Centrifuge adapter and cap
US8105556B2 (en) 2004-12-23 2012-01-31 Thermo Electron Led Gmbh Centrifuge adapter and closure
DE102004062233B4 (en) * 2004-12-23 2020-09-03 Thermo Electron Led Gmbh Centrifuge adapter and closure
US20080045395A1 (en) * 2004-12-23 2008-02-21 Romanauskas William A Centrifuge adapter and closure
US7461755B2 (en) * 2005-09-20 2008-12-09 Comar Moisture-tight safety closure and container having a flexible neck finish
US20070062900A1 (en) * 2005-09-20 2007-03-22 Manera David A Moisture-tight safety closure and container having a flexible neck finish
EP2190581A1 (en) * 2007-08-21 2010-06-02 Nalge Nunc International Corporation Centrifuge bottle closure and assembly thereof
EP2190581A4 (en) * 2007-08-21 2011-06-08 Nalge Nunc Int Corp Centrifuge bottle closure and assembly thereof
US8215508B2 (en) 2007-08-21 2012-07-10 Nalge Nunc International Corporation Centrifuge bottle closure and assembly thereof
US20090054221A1 (en) * 2007-08-21 2009-02-26 Nalge Nunc International Centrifuge bottle closure and assembly thereof
WO2009026436A1 (en) 2007-08-21 2009-02-26 Nalge Nunc International Corporation Centrifuge bottle closure and assembly thereof
US20100258698A1 (en) * 2009-04-14 2010-10-14 Wunderwall, LLC Cup for holding bottles in a bottle rack
US8267259B2 (en) * 2009-04-14 2012-09-18 Wunderwall, LLC Cup for holding bottles in a bottle rack
WO2012130016A1 (en) * 2011-03-31 2012-10-04 Chen Yuxiang Seal cover with flexible interface
US9987634B2 (en) * 2014-12-03 2018-06-05 Fiberlite Centrifuge, Llc Centrifuge sample container and closure therefor
US20160158744A1 (en) * 2014-12-03 2016-06-09 Fiberlite Centrifuge, Llc Centrifuge Sample Container And Closure Therefor
USD777342S1 (en) * 2014-12-03 2017-01-24 Fiberlite Centrifuge, Llc Centrifuge bottle handle
US10112199B2 (en) 2014-12-03 2018-10-30 Fiberlite Centrifuge, Llc Centrifuge sample container and closure therefore
USD777941S1 (en) * 2015-07-17 2017-01-31 Fiberlite Centrifuge, Llc Centrifuge bottle
USD817510S1 (en) * 2015-07-17 2018-05-08 Fiberlite Centrifuge, Llc Centrifuge bottle handle
USD819827S1 (en) 2015-07-17 2018-06-05 Fiberlite Centrifuge, Llc Centrifuge bottle handle
US10220983B1 (en) * 2015-07-27 2019-03-05 James R. Gilliam Threaded bottle ring and method of fabrication and attachment
US11883818B2 (en) 2017-07-27 2024-01-30 Biomerieux, Inc. Isolation tube
US11090646B2 (en) 2017-07-27 2021-08-17 Biomerieux, Inc. Isolation tube
US11305273B2 (en) 2017-07-27 2022-04-19 Biomerieux, Inc. Isolation tube with a rheological control member and a plunger
US11325117B2 (en) * 2017-07-27 2022-05-10 Biomerieux, Inc. Centrifugally separating samples in a container having a seal and containing a plunger for opening the seal
US11383231B2 (en) 2017-07-27 2022-07-12 Biomerieux, Inc. Isolation tube
US11440000B2 (en) * 2017-07-27 2022-09-13 Biomerieux, Inc. Isolation tube with an endcap
US11918998B2 (en) 2017-07-27 2024-03-05 BIOMéRIEUX, INC. Assembly comprising a sample collection vessel and a separation container having seal, plunger with seal-piercing point, retainer, and flexible sealing member
US11850584B2 (en) 2017-07-27 2023-12-26 Biomerieux, Inc. Isolation tube
USD908001S1 (en) * 2018-09-04 2021-01-19 Jean-Pierre Pinard Cap for a bottle
US11440712B2 (en) * 2018-12-27 2022-09-13 Indrio Brands, Llc Beverage container system and components

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