|Publication number||US3217707 A|
|Publication date||16 Nov 1965|
|Filing date||29 Oct 1962|
|Priority date||2 Nov 1961|
|Also published as||DE1223992B|
|Publication number||US 3217707 A, US 3217707A, US-A-3217707, US3217707 A, US3217707A|
|Original Assignee||Werding Winfried|
|Export Citation||BiBTeX, EndNote, RefMan|
|Patent Citations (2), Referenced by (59), Classifications (17)|
|External Links: USPTO, USPTO Assignment, Espacenet|
Nov. 16, 1965 w. WERDING 3,2173%? APPARATUS FOR TREATMENT OF ARTERIAL CIRCULATION DISTURBANCES AND RHEUMATISM Filed Oct. 29, 1962 INVENTOR W/NFRIED WERDING 5 WWW ATTo/VEYS United States Patent M 3,217,707 APPARATUS FOR TREATMENT OF ARTERIAL CIgCULATION DISTURBANCES AND RHEUMA- Ti M Winfried Werding, 25 Ave. de Chailly, Lausanne, Switzerland Filed Oct. 29, 1962, Ser. No. 233,616
Claims priority, application Switzerland, Nov. 2, 1961,
12,680/ 61 6 Claims. '(Cl. 128-241) This invention relates to apparatus for the treatment of disturbances in the circulation of blood and various forms of rheumatic diseases of the upper and lower limbs of the human body.
The object of the present invention is to provide an apparatus for the treatment of disturbances in the circulation of blood and various forms of rheumatic discases of the upper and lower limbs of the human body which apparatus has a receptacle for receiving a limb and an inflatable sleeve for airtight sealing as well as control means for the operation of a pump unit for the production of an excess pressure or reduced pressure in the receptacle.
For the treatment of arterial circulation disturbances and rheumatism, apparatus is known having a glass cylinder for receiving the limb to be treated. The airtight sealing of the glass cylinder is effected by means of rubber sheaths and rubber bandages. Connected to the glass cylinder is a vacuum pump to be operated by hand for producing a reduced pressure which results in a widening of the vessels of the limb inserted in the cylinder whereby a hyperaemia is released. The suction produced results in a firm pressing of the rubber sheath onto the limb and thereby prevents the venous return flow.
For determining the duration of the reduced pressure of air in the cylinder a valve is provided which according to the hyperaemia reaction is held closed for several minutes. By the opening of the valve the rarefaction of the air in the cylinder is terminated whereby the construction is relaxed and the venous return flow is restored.
By means of the use of inflatable sleeves and an electronic control in conjunction with the known apparatus it has become possible to subject the limbs to be treated also to an excess pressure whereby the indication area is enlarged. It has been proved however, that the inflatable sleeves, according to the type of treatment to be effected, for example, alternating excess and under pressure phases, elfect an extraordinarily considerable construction of the limb and thus prevent a premature venous return flow whereby the exposure of the limb to great rarefaction of air leads to great pain. One therefore can no longer obtain with a very full sleeve the widening of the vessels exclusively by the rarefaction of air but only by a venous congestion by constriction.
The object of the invention is to provide a fundamental improvement of the known apparatus in the sense that the inflatable sleeve can be filled and emptied automatically in proportion to the pressure ratio in the cylinder in order to extend the field of use of the apparatus and to facilitate the maintaining of the circulation of the blood so that the venous return flow can also take place during the phase of the rarefaction of air in that the rarefaction of air brings about a widening of the blood and lymph vessels. This widening results in an increased quantity of blood and lymph in the limb to be treated whereby the feeding of the tissue is increased or when there is a deficiency it is reestablished as far as possible.
The apparatus according to the present invention is 3,217,707 Patented Nov. 16, 1965 characterised in that one end of the receptacle is closed by means of a wall carrying an air supply connection, a thermostat, a blower and a heating and cooling device while the other end of the container has a removable airtight lid with a sleeve connection with an air supply and an inflatable sleeve connected to the inner wall of this connection and that means are provided which control the pressure and the temperature within the receptacle and the pressure within the inflatable sleeve automatically according to a variable program whereby upon an excess pressure occurring in the receptacle the sleeve fills such that it excludes a leakage of the excess pressure from the receptacle and with an intended reduction in pressure does not prevent the return flow of blood in the venous system.
The above stated and further objects of the invention will be apparent from the following description of one embodiment of the apparatus which is shown diagrammatically in the accompanying drawing and in conjunction with the various control means.
The apparatus comprises a receptacle 1 adapted to receive the limb to be treated which container is closed airtight at one end by a Wall 2. On the inside of the wall 2 are fixed a thermostat 3 for the regulation of the temperature inside the receptacle 1 and a blower 4 with heating and cooling coil 5. The other end of the container 1 is capable of being closed by means of a lid 6 on which is located a connection piece 7 for the application of an inflatable sleeve 8. The sleeve 8 is made of a thin rubber tube the edges 8a and 8b of which are fixed to the inner wall of the connection piece 7. The connection piece 7 has a bore which has a connection with an air connection 7a through which compressed air for the inflation of the sleeve can be let in or let out in order that the latter after the insertion of the limb to be treated always remains in contact with the latter in an airtight manner. The lid 6 and its sleeve connection 7 are preferably made of thicker rubber so that the lid upon reduced pressure in the receptacle takes up the position I shown in dot and dash lines in the drawing. While upon excess pressure in the receptacle it is adjusted to a position II.
Associated With the apparatus is a regulatable pressure and vacuum pump 9 the pressure side of which is connected via an air pipe 10 to the inflatable sleeve 8. The pipe 10 has an excess pressure valve 11 and comprises also a relay-operated valve 12, a non-return valve 13 connected to the latter and a manually adjustable throttle valve 14. For the control of the relay-operated valve 12 there is provided a pressure regulator 15 with adjustable minimum and maximum pressure which is connected by means of a tube piece 16 to the pipe 10 such that the air pressure behind the throttle valve 14 and thus that in the inflatable sleeve 8 is effective. A further branch 17 with a throttle valve 18 and a relayoperated valve 19 is connected to the branch of the pipe 10 which lies between the inflatable sleeve 8 and the throttle valve 14. The relay-operated valve 19 is likewise controlled by the pressure regulator 15 which in its turn is connected electrically via a wire 21 to a constant voltage source 20.
In front of the relay-operated valve 12, a further air pipe 22 branches off from the air pipe 10 and from which a branch is provided via a relay-operated valve 24. From the relay-operated valve 23 the air pipe 22 leads via a non-return valve 25 and a throttle valve 26 to a connection piece 27 on the wall 2 of the receptacle 1. The connection piece makes the connection of the air pipe 22 to the inside of the receptacle 1. For the control of the relay-operated valves 23 and 24 a further pressure regulator 28 with adjustable minimum and maximum pressure is used. The two pressure regulators 15 and 28 may as a contact manometer have or be in the form of a photocell control. The portion of the air pipe 22 lying between the throttle valve 26 and the connection piece 27 has a connection via a pipe 29 with a throttle valve 30 and a relay-operated valve 31 with the pressure and vacuum pump 9 to which pipe a relayoperated valve 32 and an excess pressure valve 33 as well as a branch 34 leading to the pressure regulator 28 are connected. The control of the relay-operated valves 31 and 32 is affected by means of the pressure regulator 28 which is connected to the constant voltage source 20. There are also present a time relay 35 for the regulation of the reduced pressure phases and a time relay 36 for the control of the excess pressure phases in the receptacle 1. Both time relays 35, 36 are connected to the pressure regulator 28 and to the constant voltage source 20.
The connection of the apparatus to the mains is effected via an on and off switch 38 to which are connected the constant voltage 20 and the pressure and vacuum pump 9 as well as a heating and cooling unit which latter for its part is connected to the heating and cooling coil and to the thermostat 3. The thermostat 3 is adjustable by means of a rotary knob 3a mounted on the outside of the wall 2 to give the temperature desired at the time.
The manner of operation of the apparatus is described as follows in the treatment of a dry gangrene. For this treatment it is necessary to subject the limb to an excess pressure as well as a reduced pressure, to heat the inside of the receptacle 1 to 35 C. but upon pain occurring to cool to C. As treatment values are provided:
Excess pressure 0.05 atmosphere. Maintaining constant stabilization 30 seconds. Reduced pressure 0.15 atmosphere. Maintaining constant stabilization 45 seconds. Sleeve pressure:
Maximum value 0.08 atmosphere.
Minimum value 0.01 atmosphere. Temperature:
Without pain 35 C.
With pain 10 C.
The sleeve 8 fitting the limb to be treated is fixed to the sleeve connection piece 7 and the limb is introduced through the opening of the sleeve into the container 1. The pressure regulator 28 is then adjusted to the desired excess and reduced pressure values in the receptacle 1, the pressure regulator to the maximum and minimum values of the sleeve pressure, the time relay 35 to the stabilization value of the reduced pressure, the time relay 36 to the stabilization value of the excess pressure and the thermostat 3 to the temperature in the receptacle.
After the switching on of the switch 33 the blower 4 begins to run and the heating coil 5 produces heat until the temperature set on the thermostat 3 is attained whereupon the heating device is automatically switched 01f. In the case where instead of the heating a cooling is to be effected the heating coil 5 is to be replaced by a cooling coil. In this case the switching off of the blower 4 is effected as soon as the temperature set on the thermostat is reached.
For the automatic regulation of the pressure ratios between the pressure within the sleeve 8 and that in the receptacle 1, the throttle valves 30, 26, 18 and 14 are used whereby care should be taken that the throttle effect by the throttle valve 30 must be smaller than that of the throttle valve 18 and that the throttle effect of the throttle valve 26 must be greater than the throttle effect of the throttle valve 14. The non-return valves 13 and 25 prevent an equalization of pressure between the sleeve 8 and the casing 1. This measure is necessary because the sleeve 8 at the beginning has to take a larger quantity of air than the casing 1 in order that a satisfactory application of the sleeve to the limb is ensured. In this way the necessary sealing of the casing is first effected which only then makes an increase of pressure within the casing possible.
When the maximum value of the sleeve pressure is attained the relay-operated valve 12 closes. In setting this maximum value on the pressure regulator 15 care is to be taken that the increase in pressure in the receptacle 1 results in an increase of pressure in the sleeve 8 readable on the pressure regulator. This pressure effect coming from outside must be added to the pressure existing in the sleeve 8 itself whereby the maximum value of the sleeve pressure to be set at the beginning turns out to be higher than the pressure in the receptacle 1. Experiments which have been carried out resulted in a difference of about 0.03 atmosphere. If therefore the pressure present in the receptacle 1 is to be 0.05 atmosphere then the maximum value of the sleeve pressure must be adjusted in the first place to 0.08 atmosphere with the result that the relay-operated valve 12 only closes when in the receptacle 1 the pressure of +5 (0.05 is actually reached.
The minimum value of the sleeve pressure depends on the disease to be treated as there are cases in which a certain constriction proves to be favorable. Thus the zero value of the pressure regulator 15 corresponds to the pressure which is necessary in order to press the sleeve 3 onto the limb such that it contacts the skin. This pressure suffices to prevent a flowing in of air at the commence of the rarefaction of air in the receptacle 1. If one wishes therefore to bring about a certain constriction one must increase the minimum value of the sleeve pressure whereby at the commencement of the reduced pressure a certain pressure remains in the sleeve 8 which places the sleeve firmly into contact with the limb so that during the phase of the rarefaction of air a constriction and thereby a stronger or weaker prevention of the venous return flow is brought about.
Due to the weaker throttling at the throttle valve 30 in proportion to the throttling at the throttle valve 18 the pressure in the casing 1 dissipates more rapidly than in the sleeve 8 and the reduced pressure in the receptacle already begins before the sleeve pressure has reached the set minimum value. The reduced pressure in the receptacle 1 effects a continuously stronger suction of the sleeve on the limb. As the limb however offers a resistance the same is expressed by a measurable increase of pressure in the sleeve 8. This increase of pressure may be drawn off by opening of the relay-operated valve 19. If therefore the minimum valve of the sleeve pressure is set such that it is under the value necessary for adopting the sleeve at 0 pressure onto the limb so that it contacts the skin (zero value of the sleeve pressure) then one causes thereby the sleeve 3 during the reduced pressure phase of the treatment to give the pressure which is necessary or would be necessary to produce a reduced pressure in the receptacle 1. This prevents to a great extent a constriction of the limb by the sleeve 8 so that the venous return flow can also be maintained even during a greatly reduced pressure. At 0 pressure the atmospheric outer pressure applies which exists also in the inside of the receptacle before the switching on of the apparatus.
If in the treatment set forth of a dry gangrene the relay-operated valves 31, 24 and 19 are closed and the relay-operated valves 32, 23 and 12 open then the sleeve 8 and the receptacle 1 fill with compressed air. If the set maximum values are reached then the relay-operated valves 31, 23, 19 and 12 close while the relay-operated valves 32 and 24 open. The time relay 36 effects the stabilization of these positions during the set period. After expiration of this period the relay-operated valves 32, 23 and 12 close while the relay-operated valves 31, 24 and 19 open. The sleeve 8 and the receptacle 1 can now empty. If the minimum value of the sleeve pressure set is reached, the relay-operated valves 32, 23, 19 and 12 are closed and the relay-operated valves 31 and 24 are opened so that in the receptacle 1 a pressure reduction is brought-about. If the maximum value of air rarefaction set is reached then the relay-operated valves 31, 23, 19 and 12 are closed while the relay-operated valves 32 and 24 are opened. The time relay 28 effects the stabilization of this position during the set period after expiration of which the relay-operated valves 31, 23, 19 and 12 close and the relay-operated valves 32 and 23 open with the result that the receptacle 1 receives compressed air and the air rarefaction disappears. If the set minimum value of the sleeve pressure is reached, the relay-operated valves 31, 24 and 19 close and the relayoperated valves 32, 23 and 12 open which position corre sponds to the above mentioned starting position.
The treatment phases described run according to the duration of treatment for 20 minutes to hours returning always to the sequence set forth and thus effect the therapy. In consequence of the automatic sequence special supervision is not necessary.
For reasons of safety for the pressure regulators 28 and 15 the excess pressure valves 33 and 11 are provided as well as the member ensuring the constant voltage. There are also safety devices, not shown, present in the individual circuits.
1. Apparatus for the treatment of disturbances in the circulation of the blood and various forms of rheumatic diseases of the upper and lower limbs of the human body comprising a hollow receptacle having an opening, a closure member mounted on said receptacle across said opening and having a tubular extension with said closure member and tubular extension being formed of a semirigid material, an inflatable sleeve fixedly mounted within said tubular extension and being capable of having the limb to be treated extending therethrough into said receptacle, means for heating and cooling the interior of said receptacle, a source of compressed air connected to said receptacle and said sleeve, relay operated valves for controlling the pressure in said sleeve in proportion to the pressure inside said receptacle interconnected between said source of compressed air and said sleeve and receptacle and means for regulating said valve relays and said heating and cooling means according to a variable program of treatment for the limb.
2. Apparatus for the treatment of disturbances in the circulation of blood and various forms of rheumatic diseases of the upper and lower limbs of the human body comprising an elongated hollow receptacle having an open end, a lid for closing said receptacle open end and having a tubular extension for receiving the limb to be treated extending therethrough into said receptacle, said lid and its extension being formed of a semi-rigid material, an inflatable sleeve fixedly mounted in said lid extension, means for heating and cooling the interior of said receptacle, a pressure and vacuum pump, air conveying means connecting said pump to said receptacle and said sleeve and automatic means for controlling the flow of air through said air conveying means and the temperature provided by said heating and cooling means as desired.
3. Apparatus as claimed in claim 2 wherein said air conveying means consists of a pair of pipes with one pipe connected to said receptacle and the other to said sleeve and including a pair of individually regulatable throttle valves each interconnected in one of said pipes being adjustable for permitting a greater quantity of air to flow into said sleeve than into said receptacle and a greater quantity of air to flow out of said receptacle than out of said sleeve.
4. Apparatus as claimed in claim 2 wherein said air conveying means consists of a pair of pipes with one pipe connected to said receptacle and the other pipe to said sleeve and including a pair of individually regulatable throttle valves each interconnected in one of said pipes and a non-return valve interconnected in said pipe connected to said sleeve for preventing equalization of pressure between said sleeve and said receptacle.
5. Apparatus as claimed in claim 2 including a pressure regulator in fluid circulation with said sleeve.
6. Apparatus as claimed in claim 2 including a pressure regulator in fluid circulation with said receptacle.
References Cited by the Examiner UNITED STATES PATENTS 1,110,494 9/1914 Kellogg 128402X 2,655,145 10/1953 Heger 12824.1
RICHARD A. GAUDET, Primary Examiner.
RICHARD J. HOFFMAN, Examiner.
|Cited Patent||Filing date||Publication date||Applicant||Title|
|US1110494 *||13 Jul 1912||15 Sep 1914||Therapeutic apparatus.|
|US2655145 *||14 Jun 1948||13 Oct 1953||Guillaume Heger||Apparatus for a percutaneous treatment|
|Citing Patent||Filing date||Publication date||Applicant||Title|
|US3599631 *||18 Jul 1969||17 Aug 1971||Contimed Sa||Apparatus for medically treating circulatory ailments of the human body|
|US3712298 *||25 Aug 1970||23 Jan 1973||Nat Res Dev||Medical treatment apparatus|
|US4003371 *||28 Jan 1976||18 Jan 1977||Fischer Boguslav||Low pressure hyperbaric chamber|
|US4376437 *||19 Jul 1979||15 Mar 1983||Sundheim Benson R||Topical environmental device|
|US4691695 *||4 Oct 1985||8 Sep 1987||Deutsche Forschungs- Und Versuchsanstalt Fur Luft- Und Raumfart E.V.||Apparatus for medical treatments|
|US6846322||21 Nov 2001||25 Jan 2005||Dynatherm Medical, Inc.||Apparatus and method for manipulating core body temperature|
|US7128735||30 Dec 2004||31 Oct 2006||Richard Scott Weston||Reduced pressure wound treatment appliance|
|US7160316||23 Sep 2004||9 Jan 2007||Dynatherm Medical, Inc.||Methods and apparatus for adjusting body core temperature|
|US7708724||4 Apr 2005||4 May 2010||Blue Sky Medical Group Incorporated||Reduced pressure wound cupping treatment system|
|US7776028||31 Mar 2005||17 Aug 2010||Bluesky Medical Group Incorporated||Adjustable overlay reduced pressure wound treatment system|
|US7833179 *||30 Dec 2003||16 Nov 2010||Otivio As||Device for applying a pulsating pressure to a local region of the body and applications thereof|
|US7833180||9 Oct 2008||16 Nov 2010||Otivio As||Device for applying a pulsating pressure to a local region of the body and the applications thereof|
|US7846141||28 Aug 2003||7 Dec 2010||Bluesky Medical Group Incorporated||Reduced pressure treatment system|
|US7909805||4 Apr 2005||22 Mar 2011||Bluesky Medical Group Incorporated||Flexible reduced pressure treatment appliance|
|US7998125||19 May 2005||16 Aug 2011||Bluesky Medical Group Incorporated||Hypobaric chamber treatment system|
|US8021314||11 Oct 2010||20 Sep 2011||Otivio As||Device for applying a pulsating pressure to a local region of the body and the applications thereof|
|US8062272||24 Feb 2005||22 Nov 2011||Bluesky Medical Group Incorporated||Flexible reduced pressure treatment appliance|
|US8062273||6 Dec 2010||22 Nov 2011||Bluesky Medical Group Incorporated||Reduced pressure treatment system|
|US8066752||4 Dec 2006||29 Nov 2011||Dynatherm Medical, Inc.||Methods and apparatus for adjusting body core temperature|
|US8100887||8 Mar 2005||24 Jan 2012||Bluesky Medical Group Incorporated||Enclosure-based reduced pressure treatment system|
|US8182521||30 Jul 2007||22 May 2012||Dynatherm Medical Inc.||Methods and apparatus for increasing blood circulation|
|US8361001||17 Aug 2011||29 Jan 2013||Otivio As||Device for applying a pulsating pressure to a local region of the body and the applications thereof|
|US8398614||1 Apr 2009||19 Mar 2013||Smith & Nephew Plc||Apparatus for aspirating, irrigating and cleansing wounds|
|US8449509||7 Jul 2010||28 May 2013||Bluesky Medical Group Incorporated||Flexible reduced pressure treatment appliance|
|US8540699||13 Aug 2010||24 Sep 2013||Bluesky Medical Group Incorporated||Reduced pressure wound treatment system|
|US8545464||23 Apr 2012||1 Oct 2013||Bluesky Medical Group Incorporated||Reduced pressure treatment system|
|US8569566||22 Nov 2011||29 Oct 2013||Smith & Nephew, Plc||Wound cleansing apparatus in-situ|
|US8603150||11 Oct 2007||10 Dec 2013||Carefusion 2200, Inc.||Methods and apparatus for adjusting blood circulation|
|US8628505||22 Nov 2011||14 Jan 2014||Bluesky Medical Group Incorporated||Reduced pressure treatment system|
|US8657864||16 Dec 2008||25 Feb 2014||Otivio As||Portable patient temperature adjustment apparatus and method|
|US8708998||7 Apr 2009||29 Apr 2014||Bluesky Medical Group, Inc.||Enclosure-based reduced pressure treatment system|
|US8771329||7 Jan 2011||8 Jul 2014||Carefusion 2200, Inc.||Methods and apparatus for enhancing vascular access in an appendage to enhance therapeutic and interventional procedures|
|US8821422||21 Dec 2012||2 Sep 2014||Otivio As||Device for applying a pulsating pressure to a local region of the body and applications thereof|
|US8834451||31 Jan 2012||16 Sep 2014||Smith & Nephew Plc||In-situ wound cleansing apparatus|
|US8926592||7 Jul 2010||6 Jan 2015||Smith & Nephew Plc||Wound cleansing apparatus with heat|
|US9198801||24 May 2013||1 Dec 2015||Bluesky Medical Group, Inc.||Flexible reduced pressure treatment appliance|
|US9205001||12 Sep 2014||8 Dec 2015||Smith & Nephew Plc||Apparatus for aspirating, irrigating and cleansing wounds|
|US9211365||27 Dec 2013||15 Dec 2015||Bluesky Medical Group, Inc.||Reduced pressure treatment system|
|US9272080||30 Jul 2014||1 Mar 2016||Bluesky Medical Group Incorporated||Flexible reduced pressure treatment appliance|
|US9289542||18 Dec 2014||22 Mar 2016||Smith & Nephew Plc||Wound cleansing apparatus|
|US9308148||27 Nov 2007||12 Apr 2016||Thermatx, Inc.||Methods and apparatus for adjusting blood circulation|
|US9446178||17 Aug 2011||20 Sep 2016||Smith & Nephew Plc||Wound cleansing apparatus in-situ|
|US9452248||18 Dec 2014||27 Sep 2016||Smith & Nephew Plc||Wound cleansing apparatus in-situ|
|US9492326||7 May 2013||15 Nov 2016||Bluesky Medical Group Incorporated||Reduced pressure wound treatment system|
|US20050027218 *||30 Dec 2003||3 Feb 2005||Marius Filtvedt||Device for applying a pulsating pressure to a local region of the body and applications thereof|
|US20050148913 *||30 Dec 2004||7 Jul 2005||Weston Richard S.||Reduced pressure wound treatment appliance|
|US20050209663 *||23 Sep 2004||22 Sep 2005||Nathan Hamilton||Methods and apparatus for adjusting body core temperature|
|US20070112400 *||4 Dec 2006||17 May 2007||Nathan Hamilton||Methods and apparatus for adjusting body core temperature|
|US20090036959 *||9 Oct 2008||5 Feb 2009||Thermanor As||Device for applying a pulsating pressure to a local region of the body and the applications thereof|
|US20100152633 *||16 Dec 2008||17 Jun 2010||Thermanor As||Portable patient temperature adjustment apparatus and method|
|US20100152821 *||16 Dec 2008||17 Jun 2010||Thermanor As||Portable patient temperature adjustment apparatus and method|
|US20110021960 *||11 Oct 2010||27 Jan 2011||Otivio As||Device for applying a pulsating pressure to a local region of the body and the applications thereof|
|EP0767640A1 *||8 Mar 1996||16 Apr 1997||The Board Of Trustees Of The Leland Stanford Junior University||Apparatus and method for core body warming of mammals experiencing hypothermia|
|EP0767640A4 *||8 Mar 1996||25 Aug 1999||Univ Leland Stanford Junior||Apparatus and method for core body warming of mammals experiencing hypothermia|
|EP1884226A1 *||2 Aug 2007||6 Feb 2008||Dynatherm Medical, Inc.||Methods and apparatus for increasing blood circulation|
|WO2001037776A1 *||23 Nov 2000||31 May 2001||Jieliang Bi||A negative pressure treatment equipment|
|WO2002085266A1 *||19 Apr 2002||31 Oct 2002||Avacore Technologies, Inc.||Heat-exchange device with improved seal|
|WO2003045289A1 *||21 Nov 2002||5 Jun 2003||Dynatherm Medical Inc.||Apparatus and method for manipulating core body temperature|
|WO2016020536A1 *||7 Aug 2015||11 Feb 2016||Zimmer, Bernd||Transportable therapy device for the therapeutic treatment of at least one person, in particular of a painful state of a limb of the person|
|International Classification||A61H9/00, A61M1/02, A61F7/02|
|Cooperative Classification||A61H9/005, A61H9/00, A61H2201/0214, A61H2201/0207, A61F2007/0296, A61H2201/025, A61H9/0071, A61F7/007, A61F2007/0001, A61F2007/0239|
|European Classification||A61H9/00, A61H9/00P, A61F7/00E|