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Publication numberUS2959964 A
Publication typeGrant
Publication date15 Nov 1960
Filing date24 Jul 1956
Priority date24 Jul 1956
Publication numberUS 2959964 A, US 2959964A, US-A-2959964, US2959964 A, US2959964A
InventorsStreitfeld Murray M
Original AssigneeNat Children S Cardiac Hospita
Export CitationBiBTeX, EndNote, RefMan
External Links: USPTO, USPTO Assignment, Espacenet
Pipette adaptor
US 2959964 A
Abstract  available in
Previous page
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Claims  available in
Description  (OCR text may contain errors)

Nov. 15, 1960 M. M. STRE ITFELD PIPETTE ADAPTOR Filed July 24, 1956 INVENTOR ATTORNEY United States Patent 2 O PIPETTE ADAPTOR Murray M. Streitfeld, Miami, Fla., assignor of seventyfive percent to National Childrens Cardiac Hospital, a not-for-profit corporation of Florida Filed July 24, 1956, Ser. No. 599,854-

4 Claims. (Cl. 73425.6)

This invention relates to the detachable coupling of pipettes or like slender tubing to suction devices and has more especial reference to a pipette-to-syringe adaptor, the main object of the invention being, first, the provision of a connection of this character which enables dangerous biological or chemical fluids to be measured quantitatively and safely transferred from one container to another; and, second, to design the adaptor for use with available laboratory equipment.

Another and important object of the invention is the elimination of oral pipetting of dangerous fluids.

The invention is particularly adaptable for use with the standard type of glass syringe having a tapered nipple around which the adaptor makes an air-tight connection. In some instances this type of syringe is provided with means encircling the nipple, such as the well known Luer-Lok, for the attachment of a needle, and it is a further object of the invention to so form the tip, or nipple engaging end of the adaptor, as to detachably engage such needle attaching means in interlocking relation.

Removable connection of the pipette is by its insertion into the bore of a pliable sleeve housed within the adaptor, and it is a further object of the invention to make provision for this sleeve being readily removable in order that sleeves of diflering internal diameter may be substituted one for another to accommodate pipettes of various sizes.

A still further object of the invention is the provision of means for the accurate control of air pulled through the adaptor.

Briefly described the invention consists of a detachable coupling between a suction device and a pipette, such coupling having means in its air passage for accurate control of air drawn through the passage. This coupling, or adaptor, has a reduced tip end and a body portion, the latter preferably being cylindrical. The tip end has a sliding fit over the tapered nipple of the suction device and is formed with means for interlocking engagement within a needle attachment should such device be so equipped. The body portion is formed with a chamber open at one end for receiving a sleeve of pliable material which makes an air-tight seal with that part of a pipette inserted therein. The sleeve is interchangeable for the reason herein set forth, with others of different internal diameter and means provided for removably holding the sleeve in place.

The accompanying drawings illustrating a preferred embodiment of the invention and forming a part of the following more detailed description are as follows:

Fig. 1 is an exploded view showing in elevation the adaptor and associated parts viz., a syringe and a pipette with which the adaptor is to be coupled, intermediate portions of the syringe being broken away.

Fig. 2 is a greatly enlarged sectional view taken axially through the adaptor, fragmentary portions of the syringe and the pipette to which the adaptor is connected being seen in elevation.

2,959,994 Patented Nov; 15, IQGQ ice Fig. 3 is a plan view of the neck or tip end portion of the adaptor.

Fig. 4 is a view in elevation of the part seen in Fig. 3.

Fig. 5 is a fragmentary sectional detail of the tip end of the adaptor showing a variation of the invention to be explained below.

Fig. 6 is a detail in plan view of the split retaining ring.

In the drawings similar reference numerals refer to similar parts throughout the several views.

The illustrated embodiment of the suction device is a standard type of glass syringe comprising a barrel 7,. a manually operable plunger 8 slidable in and longitudinally of the barrel 7, a nipple 9 extending downward from the bottom of the barrel, and a needle attachment 10 encircling the nipple 9'and commonly known as the Lucr- Lok. A pipette having calibration markings thereon and a tapered tip end is shown at 11.

The adaptor comprises a jacket preferably of metal and formed of two parts, viz., a body portion, indicated generally by numeral 12, and a neck portion similarly indicated by numeral 13. The body 12 has an axial bore which provides a chamber 14 open at its outer end, this chamber 14 having a side wall 15 and an end wall 16. Extending through the end wall 16 is a bore 17 communicating with the chamber 14. Adjacent to the open end of chamber 14 is an annular recess 18 in the inner face of the side wall 15.

The neck portion 13 of the jacket is tooled to form a flange or shoulder part 19 from the opposite faces of which are axially aligned inner and outer extensions 20 and 21, respectively. Extension 20 is rigidly fixed to the body 12 by having a force fit within the opening 17, the joint between the end wall 16 of the body 12 and the shoulder part 19 of the neck portion 13 being sealed by a packing ring 22. The neck 13 has an axial bore 23 which terminates adjacent the inner endof the neck in a restricted opening 24 communicating with the chamber 14. The outer extension 21 of the neck is the tip end of the adaptor and forms an air-tight slip connection with the inserted nipple 9 of the syringe as illustrated in Fig. 2. Should the nipple be tapered, as at 9a in Fig. 5, there will be a like slip fit with the correspondingly tapered outer end 25 of the bore 23.

Formed on the free end of the'neck part '21: are out= wardly turned, opposing flange segments 26 which enter the locking sleeve comprising the part 10 encircling the nipple 9. By relative rotation of the adaptor and the syringe through an angle of the segments 26 will engage with cam action above and against similar oppos ing segments 27 of an internal thread on the part 10. In this manner the adaptor and syringe are detachably held in interlocking engagement without danger of accidental separation.

An air-tight seal at the same time is made between the nipple 9 and the tip end 21 of the adaptor in the manner above stated.

Housed within the chamber 14 in contact with the side wall 15 and end wall 16 of the body portion 12 is a resilient sleeve 28 made preferably of a pliable material such as silicone rubber. This sleeve 28 is held in place by a split spring ring 29 inserted in the recess 18 and a spacing ring 30 interposed between the sleeve and the split ring. The upper end of the pipette 11 is inserted in the resilient sleeve 28, as clearly illustrated in Fig. 2, which yieldingly holds the pipette against removal. The connection thus made between the pipette 11 and the adaptor is air-tight.

It will be observed that the sleeve 28 is readily and easily removable by compressing and removing split ring 29 and removing spacing ring 30. The sleeve 28 can then be removed and replaced with any one of a set of a plurality of sleeves of differing internal diameters. This is for the interchange of sleeves differing in internal diameter so as to accommodate pipettes of correspondingly various sizes.

Drawing back the syringe plunger 8 induces the necessary vacuum to suck fluids up into the pipette 11. And, pushing the plunger 8 back into the barrel 7 forces fluid out of the pipette, quantitatively, as measured by the pipette and governed by the pressure on the plunger 8. The restricted opening 24 serves to give close and accurate control of quantitative pipetting of dangerous fluids to a greater extent than has been possible with prior art devices.

Furthermore the advantage of this technique is the elimination of oral pipetting of dangerous fluids, while allowing transfer of such materials accurately measured by standard quantitative laboratory equipment.

It is believed that from the foregoing the construction and operation of the invention have been made clear and is limited only by the following claims.

I claim:

1. As an article of manufacture, a detachable pipette to syringe coupling comprising in combination a rigid structure including a tubular body portion, an elongated neck portion and a transverse intermediate portion providing a dividing wall from which the said body and neck portions extend in opposite directions, said body portion providing an outwardly opening end chamber and 'having an inner annular recess, said neck portion having a longitudinal bore from its outer end for slip fit connection with a syringe nipple and said dividing wall having a restricted aperture communicating with said bore and said chamber, the said bore, chamber and restricted aperture being in axial alignment; a liner of resilient material for said tubular body portion and in endwise abutment with said dividing wall, a split ring removably insertable in said recess and a spacing sleeve interposed between said resilient liner and said split ring.

2. As an article of manufacture, a means for coupling two rigid tubes in axial alignment, one of such tubes being a pipette, and the other the taper tip end of a syringe nipple, said coupling means comprising in combination a rigid member having a longitudinal passage there through, with such passage constituting in axial alignment an annular chamber atone end having an annular recess in its side wall, a bore of less diameter than said chamber for slip fit engagement with said nipple, and a short restricted opening between said bore and said chamber, a resilient liner insertable in said chamber and in which the pipette is slidably held in relative yielding engagement, and laterally expandable liner retaining means insertable in said recess.

3. As an article of manufacture, a means for coupling in axial alignment a pipette and a hypodermic syringe, the latter having a nipple and a guard surrounding a portion of the nipple, said coupling means comprising in combination a rigid body member having a longitudinal passage therethrough with such passage constituting in axial alignment an annular chamber at one end having an annular recess in its side wall, a bore of less diameter than said chamber for slip fit engagement with said nipple and a short restricted opening between said bore and said chamber, a resilient liner insertable in said chamber and in which the pipette is slidably held in relative yielding engagement, laterally expandable liner retaining means insertable in said recess, and means integral with said body member for interlocking engagement with the said nipple guard.

4. An adaptor comprising a body portion and a neck portion, said body portion including an annular side wall and an end wall to provide a chamber open at its outer end, said end wall having an axial opening therethrough and said side wall having an annular recess in its inner surface, the said neck portion including a flange abutting said end wall and opposing outer and inner extensions from said flange, said inner extension being seated and rigidly held by force fit in said end wall opening and said outer extension being the tip end of the adaptor, said neck having an axial bore from the outer end of said tip and terminating in a restricted opening communicating with said chamber, a removable inner sleeve of resilient material in said chamber and in engagement with the said side and end walls of said body portion, a split retainer ring removably seated in said annular recess, and a spacing ring interposed between said sleeve and said retainer ring.

References Cited in the file of this patent UNITED STATES PATENTS 2,348,831 Mathis May 16, 1944 2,599,370 Caulfield June 3, 1952 2,681,034 Mannion June 15, 1954 2,767,710 Blackman Oct. 23, 1956 FOREIGN PATENTS 858,148 Germany Dec. 4, 1952 914,790 Germany July 8, 1954

Patent Citations
Cited PatentFiling datePublication dateApplicantTitle
US2348831 *27 Feb 194116 May 1944Clay Adams Co IncSafety device for pipettes
US2599370 *24 Nov 19483 Jun 1952Caulfield CarrieDevice for operating pipettes
US2681034 *23 Feb 195115 Jun 1954Trinity Equipment CorpMounting for sight glass assemblies
US2767710 *6 Nov 195223 Oct 1956Premo Pharmaccutical Lab IncHypodermic syringes
DE858148C *27 Mar 19434 Dec 1952Josef GriesVorrichtung zum Ansaugen einer fuer die Bestimmung der Blutsenkung erforderlichen Blutmenge
DE914790C *13 Jul 19518 Jul 1954Paul GiesePipettierapparat
Referenced by
Citing PatentFiling datePublication dateApplicantTitle
US3244009 *22 Aug 19635 Apr 1966Becton Dickinson CoAutomatic pipette
US3494201 *16 Aug 196810 Feb 1970Oxford LabPipetting system
US3498135 *13 Nov 19683 Mar 1970Baxter Laboratories IncPipette
US3595090 *17 Sep 196927 Jul 1971Drummond Instr CoApparatus for drawing fluid into, and discharging fluid from, a pipette
US4116068 *18 Mar 197726 Sep 1978Becton, Dickinson And CompanyAdapter for the aspiration nozzle of an automatic analytical instrument
US5104625 *4 Oct 198914 Apr 1992Drummond Scientific CompanyPipetter device
US5121642 *19 Dec 199016 Jun 1992Eastman Kodak CompanyLiquid sampling method and apparatus
US5218875 *13 Jan 199215 Jun 1993Volpe Stephen JCombination glass/plastic pipet tip assembly
US5509319 *21 Jun 199423 Apr 1996Geo-Microbial Technologies, Inc.Adapter for pipetter and hypodermic needle
US5726363 *2 Nov 199510 Mar 1998Kalidindi; Sanyasi R.Liquid sampler
US6186012 *29 Dec 199813 Feb 2001Battelle Memorial InstituteHand held sample tube manipulator, system and method
US68149363 Jul 20009 Nov 2004Goran EnhorningPipette assembly having a small volume disposable tip
US20050184516 *23 Feb 200425 Aug 2005Daniel SeguinPipette stabilizer
USRE30483 *19 Apr 197820 Jan 1981Baxter Travenol Laboratories, Inc.Pipette
WO2005087377A1 *4 Jan 200522 Sep 2005Matrix Technologies CorporationPipette stabilizer
WO2008068605A1 *6 Dec 200712 Jun 2008Gilson S.A.S.Tip mounting device for sampling device
U.S. Classification73/864.14, 422/931, 73/864.16
International ClassificationB01L3/02
Cooperative ClassificationB01L3/0275
European ClassificationB01L3/02E