US2560162A - Needle structure - Google Patents

Needle structure Download PDF

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Publication number
US2560162A
US2560162A US143399A US14339950A US2560162A US 2560162 A US2560162 A US 2560162A US 143399 A US143399 A US 143399A US 14339950 A US14339950 A US 14339950A US 2560162 A US2560162 A US 2560162A
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United States
Prior art keywords
needle
cannula
point
heel portion
bore
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Expired - Lifetime
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US143399A
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Garwood W Ferguson
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Becton Dickinson and Co
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Becton Dickinson and Co
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Priority to US143399A priority Critical patent/US2560162A/en
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Publication of US2560162A publication Critical patent/US2560162A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/32Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/3286Needle tip design, e.g. for improved penetration

Definitions

  • This invention relates to afunctionally improved hollow needle or cannula structure.
  • An additional object of the invention is that of furnishing a device of this type which may readily be manufactured by quantity production methods and with minimum expense; the needle structure being equally applicable to cannulae which are merely intended to pierce closures or cannulae which are primarily intended for hypodermic injection purposes.
  • Fig. 1 is a face view of a needle and showing the same mounted by a hub or coupling member such as would ordinarily be employed in connection with a needle. to puncture diaphragms of rubber or other materials providing pharmaceutical closures;
  • Fig. 2 is a fragmentary enlarged face view of the pointed needle end
  • Fig. 3 is ya side view thereof
  • Fig. 4 is an end view of the needle point
  • Fig. 5 is a sectional side view of a thin material layer pierced by a needle, also shown in section;
  • Fig. 6 is an end view of the parts as shown in Fig. 5.
  • the numeral 5 indicates a cannula or hollow needle which, as shown, may be mounted upon a hub including a forward portion 6 and a tubular rear portion
  • This hub conveniently includes as part of its assembly a shield 8.
  • the forward portion 6 of the hub is formed with a bore 9 which proneedle is pointed at its outer end as generally indicated at I0 to furnish a piercing end or part.
  • this may include a generally obliquely extending surface.
  • This surface or zone preferably embraces forward side beve'ls I I, to the rear of which the ground surface I2 extends.
  • the end of the bore I3 is defined.
  • the forward bevel surfaces II merge as at I4 and this line of merger is continued to furnish the piercing point at the extreme end of the needle.
  • the heel portion of the needle point is depressed as indicated at l5. Such depression extends to the rear of the zone of the ground surface. Also, this depression interrupts the rearvzone of the ground surface.
  • a cannula is cut to lengths in the usual manner. Also, in
  • the end of the cannula is ground to furnish the obliquely extending surface as well as the side bevels Il which interrupt or form continuations of the forward end of that surface.
  • the heel portion of the needle is subjected to pressure exerted through a press mounting a suitable tool.
  • the depression I5 is formed to dene this heel portion.
  • the cannula and the point are complete.
  • a suitable hub portion may be associated with the cannula.
  • a needle structure including a cannula I formed with a piercing point at one end. bevel surfaces extending rearwardly from said point and presenting a line of merger, a further surface extending obliquely from said bevel surfaces rearwardly across the cannula, a. heel portion at the rear end of said oblique surface and a depression formed in the heel portion.
  • a needle structure including a cannula formed with a piercing point at one end, a surface extending obliquely ⁇ from said point rearwardly across the cannula, the outer end oi' the cannula bore terminating in suchsuriace. a heel portion contiguous with said surface and having its forward boundary defined by the rear edge cannula bore terminating in such surface, a heel portion contiguous with said surface and having 'itsforward boundary deiined by the rear edge portion of the cannula bore and said heel portion being depressed throughout its entire area in the direction of the needle axis and below the outer cannula surface.
  • a needle structure including ⁇ a. cannula formed with a piercing point at one end. a surface extending obliquely from said point rearwardly across the cannula, the outer end of the cannula bore terminating in such surface, a heel portion-contiguous with said surface andhaving GARWOOD W. FERGUSON.

Description

vvides a continuation of the cannula bore.
Patented July 10, 1951 NEEDLE STRUCTURE Garwood W. Ferguson, Paterson, N. J., assigner to Becton Dickinson and Company, Rutherford, N. J., a corporation of New Jersey Application February 10, 1950, Serial No. 143,399
(Cl. 12S-221) 4 Claims.
This invention relates to afunctionally improved hollow needle or cannula structure.
It is an object of the invention to furnish a structure of this naturegwhich may pierce layers of material or skin and tissue without severing a plug from such materials.
Accordingly, in the case of a needle which is caused to puncture a diaphragm, stopper or other sealing portion of a pharmaceutical closure, material will not be cut from such closure.r Therefore, there will be no danger of the bore of the cannula becoming clogged, nor will there be any danger of a plug dropping into the receptacle to which the seal is applied. Where the invention is embodied in a hypodermic needle and the latter pierces skin and underlying tissues no embolus will be cut.
An additional object of the invention is that of furnishing a device of this type which may readily be manufactured by quantity production methods and with minimum expense; the needle structure being equally applicable to cannulae which are merely intended to pierce closures or cannulae which are primarily intended for hypodermic injection purposes.
With these and other objects in mind, reference is had to the attached sheet of drawings illustrating one practical embodiment of the invention and in which:
Fig. 1 is a face view of a needle and showing the same mounted by a hub or coupling member such as would ordinarily be employed in connection with a needle. to puncture diaphragms of rubber or other materials providing pharmaceutical closures; 1
Fig. 2 is a fragmentary enlarged face view of the pointed needle end;
Fig. 3 is ya side view thereof;
Fig. 4 is an end view of the needle point;
Fig. 5 is a sectional side view of a thin material layer pierced by a needle, also shown in section;
Fig. 6 is an end view of the parts as shown in Fig. 5.
Referring primarily to Fig. 1, the numeral 5 indicates a cannula or hollow needle which, as shown, may be mounted upon a hub including a forward portion 6 and a tubular rear portion This hub conveniently includes as part of its assembly a shield 8. The forward portion 6 of the hub is formed with a bore 9 which proneedle is pointed at its outer end as generally indicated at I0 to furnish a piercing end or part.
Referring in detail to the structure provided adjacent the point of the needle it will be seen The as in Figs. 2, 3 and 4 that this may include a generally obliquely extending surface. This surface or zone preferably embraces forward side beve'ls I I, to the rear of which the ground surface I2 extends. Within the zone of surface I2 the end of the bore I3 is defined. To the rear of this bore is the heel portion of the needle. The forward bevel surfaces II merge as at I4 and this line of merger is continued to furnish the piercing point at the extreme end of the needle.
In accordance with the present teachings, the heel portion of the needle point is depressed as indicated at l5. Such depression extends to the rear of the zone of the ground surface. Also, this depression interrupts the rearvzone of the ground surface.
To provide a unit of this character, a cannula is cut to lengths in the usual manner. Also, in
the usual manner the end of the cannula is ground to furnish the obliquely extending surface as well as the side bevels Il which interrupt or form continuations of the forward end of that surface. Thereafter, the heel portion of the needle is subjected to pressure exerted through a press mounting a suitable tool. In this manner the depression I5 is formed to dene this heel portion. Thereupon, the cannula and the point are complete. At any stage in the manufacture, a suitable hub portion may be associated with the cannula.
As a result'of the depression which is formed to provide the heel portion, no plug will be severed from a layer or layers pierced by a needle embodying the present teachings. Rather, if a thin layer I6 is punctured as shown in Figs. 5 and 6, the layer will have a ap portion I1 extending laterally from it and usually in direct sliding contact with the outer surface of the cannula 5. This ap portion will be attached through a substantial part of its circumference to layer I6. Therefore, there will be no danger of the flap beingsevered and detaching from the main layer during the piercing operation.
Where a relatively thick diaphragm or other closure layer is punctured by the needle, the point and adjacent edges of the latter will cut an arcuate slit as they initially pierce that layer. This slit may extend through substantially Continued projection of the needle will result in this slit being stretched or spread by' the wedging action of the needle surfaces. Accordingly, a plug of material will in no case be deposited within the interior of a laboratory ilaslcv or bottle with consequent objectionable appearance to the contents of that receptacle and possible contamination of such contents. Neither will a plugcome into being which will tend -to or actually ride into. the lumen of the cannula.. Where the structure is embraced inhypodermic needles, no embolus will be cut and therefore the patient will experience no danger in this connection.
Thus, among others, the several objects ot the invention as speciiically aiore noted are achieved. Obviously numerous changes in construction and rearrangement of the parts may be resorted to without departing. from the spirit of the invention as deiinedby the claims.
1. A needle structure including a cannula I formed with a piercing point at one end. bevel surfaces extending rearwardly from said point and presenting a line of merger, a further surface extending obliquely from said bevel surfaces rearwardly across the cannula, a. heel portion at the rear end of said oblique surface and a depression formed in the heel portion.
2. A needle structure including a cannula formed with a piercing point at one end, a surface extending obliquely `from said point rearwardly across the cannula, the outer end oi' the cannula bore terminating in suchsuriace. a heel portion contiguous with said surface and having its forward boundary defined by the rear edge cannula bore terminating in such surface, a heel portion contiguous with said surface and having 'itsforward boundary deiined by the rear edge portion of the cannula bore and said heel portion being depressed throughout its entire area in the direction of the needle axis and below the outer cannula surface.
4. A needle structure including `a. cannula formed with a piercing point at one end. a surface extending obliquely from said point rearwardly across the cannula, the outer end of the cannula bore terminating in such surface, a heel portion-contiguous with said surface andhaving GARWOOD W. FERGUSON.
REFERENCES CITED The following references are of record in the Ille of this patent:
UNITED STATES PATENTS Number Name Date 2,137,132 Cooley a- Nov. 15, 1938 2,409,979 Huber Oct. 22. 1946 FOREIGN PATENTS Number Country Date 466,002 Great Britain May 20, 1937 453,877 France Apr. 16, 1913 739,717
France Jan. 16, 1933
US143399A 1950-02-10 1950-02-10 Needle structure Expired - Lifetime US2560162A (en)

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Cited By (60)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2711733A (en) * 1951-08-10 1955-06-28 Jr George W Jacoby Hypodermic needle
US2728314A (en) * 1952-05-28 1955-12-27 Ideal Toy Corp Apparatus for inserting hair into a doll's head
US2728342A (en) * 1952-04-10 1955-12-27 Ohio Commw Eng Co Hollow filling and/or transfusion needle
US3071135A (en) * 1960-01-27 1963-01-01 Mfg Process Lab Inc Hollow needle
US3308822A (en) * 1964-04-02 1967-03-14 Loretta Fontano Hypodermic needle
US3448740A (en) * 1966-06-24 1969-06-10 Frank H J Figge Nonheel shaving hypodermic needle
US3893445A (en) * 1974-01-09 1975-07-08 Becton Dickinson Co Bone marrow biopsy instrument
US4020837A (en) * 1975-11-04 1977-05-03 Pharmaco, Inc. (Entire) Hollow piercing tip for vial stoppers
JPS54168092U (en) * 1978-05-18 1979-11-27
US4237892A (en) * 1979-02-16 1980-12-09 American Cyanamid Company Multi-beveled, v-shaped needle point
US4561445A (en) * 1983-05-25 1985-12-31 Joseph J. Berke Elongated needle electrode and method of making same
US4990135A (en) * 1989-08-29 1991-02-05 Truesdale Jr R Grant Inoculator and needle therefor
EP0819442A1 (en) * 1996-06-20 1998-01-21 Becton, Dickinson and Company A five beveled point geometry for a hypodermic needle
FR2757405A1 (en) * 1996-12-23 1998-06-26 Vermed Needle which prevents coring of human tissue
US5941899A (en) * 1995-03-03 1999-08-24 United States Surgical Corporation Channel-bodied surgical needle and method of manufacture
US6517523B1 (en) * 1999-03-15 2003-02-11 Kaneko Kogyo Inc. Needle for injection syringe and method for manufacturing the same
AU766720B2 (en) * 1996-06-20 2003-10-23 Becton Dickinson & Company Five beveled point geometry for a hypodermic needle
US20040030303A1 (en) * 1996-06-20 2004-02-12 Becton, Dickinson And Company Multi-beveled point needle and syringe having a multi-beveled point needle
US20040111066A1 (en) * 1996-06-20 2004-06-10 Becton, Dickinson And Company Mult-beveled point needle and syringe having a multi-beveled point needle
US20040260203A1 (en) * 2001-12-12 2004-12-23 Arkray Inc. Method and implement for opening hole in soft material
EP1532996A1 (en) 2003-11-20 2005-05-25 Novo Nordisk A/S Non grinded needle tip-geometry for an injection needle
US20050215977A1 (en) * 2004-03-25 2005-09-29 Uschold John E Needles and methods of using same
US20070123935A1 (en) * 2005-11-30 2007-05-31 Myers Gene E Method and apparatus for contemporaneous formation of a body structure opening and homologous pedicle
US20100222796A1 (en) * 2005-04-29 2010-09-02 Vivasure Medical Ltd. Interventional medical closure device
WO2014077677A1 (en) 2012-11-13 2014-05-22 Ambro B.V. Micro needle for transporting fluid across or into a biological barrier and method for producing such a micro needle
US9060751B2 (en) 2010-12-30 2015-06-23 Vivasure Medical Limited Surgical closure systems and methods
US9572558B2 (en) 2012-02-29 2017-02-21 Vivasure Medical Limited Devices and methods for delivering implants for percutaneous perforation closure
US9610070B2 (en) 2007-06-15 2017-04-04 Vivasure Medical Limited Closure device
USD794183S1 (en) * 2014-03-19 2017-08-08 Medimop Medical Projects Ltd. Dual ended liquid transfer spike
US9801786B2 (en) 2013-04-14 2017-10-31 Medimop Medical Projects Ltd. Drug container closure for mounting on open-topped drug container to form drug reconstitution assemblage for use with needleless syringe
USD801522S1 (en) 2015-11-09 2017-10-31 Medimop Medical Projects Ltd. Fluid transfer assembly
US9839580B2 (en) 2012-08-26 2017-12-12 Medimop Medical Projects, Ltd. Liquid drug transfer devices
US9850013B2 (en) 2013-03-15 2017-12-26 Vivasure Medical Limited Loading devices and methods for percutaneous perforation closure systems
US9943463B2 (en) 2013-05-10 2018-04-17 West Pharma. Services IL, Ltd. Medical devices including vial adapter with inline dry drug module
US10076352B2 (en) 2015-05-29 2018-09-18 Restoration Robotics, Inc. Implantation needle
USD832430S1 (en) 2016-11-15 2018-10-30 West Pharma. Services IL, Ltd. Dual vial adapter assemblage
US10206668B2 (en) 2014-12-15 2019-02-19 Vivasure Medical Limited Implantable sealable member with mesh layer
US10278897B2 (en) 2015-11-25 2019-05-07 West Pharma. Services IL, Ltd. Dual vial adapter assemblage including drug vial adapter with self-sealing access valve
US10285907B2 (en) 2015-01-05 2019-05-14 West Pharma. Services IL, Ltd. Dual vial adapter assemblages with quick release drug vial adapter for ensuring correct usage
US10357429B2 (en) 2015-07-16 2019-07-23 West Pharma. Services IL, Ltd. Liquid drug transfer devices for secure telescopic snap fit on injection vials
US10433826B2 (en) 2014-12-15 2019-10-08 Vivasure Medical Limited Closure apparatus with flexible sealable member and flexible support member
US10646404B2 (en) 2016-05-24 2020-05-12 West Pharma. Services IL, Ltd. Dual vial adapter assemblages including identical twin vial adapters
US10688295B2 (en) 2013-08-07 2020-06-23 West Pharma. Services IL, Ltd. Liquid transfer devices for use with infusion liquid containers
US10765604B2 (en) 2016-05-24 2020-09-08 West Pharma. Services IL, Ltd. Drug vial adapter assemblages including vented drug vial adapter and vented liquid vial adapter
US10772798B2 (en) 2016-12-06 2020-09-15 West Pharma Services Il, Ltd. Liquid transfer device with integral telescopic vial adapter for use with infusion liquid container and discrete injection vial
US10806671B2 (en) 2016-08-21 2020-10-20 West Pharma. Services IL, Ltd. Syringe assembly
US10806667B2 (en) 2016-06-06 2020-10-20 West Pharma. Services IL, Ltd. Fluid transfer devices for filling drug pump cartridges with liquid drug contents
US10945921B2 (en) 2017-03-29 2021-03-16 West Pharma. Services IL, Ltd. User actuated liquid drug transfer devices for use in ready-to-use (RTU) liquid drug transfer assemblages
USD917693S1 (en) 2018-07-06 2021-04-27 West Pharma. Services IL, Ltd. Medication mixing apparatus
USD923812S1 (en) 2019-01-16 2021-06-29 West Pharma. Services IL, Ltd. Medication mixing apparatus
USD923782S1 (en) 2019-01-17 2021-06-29 West Pharma. Services IL, Ltd. Medication mixing apparatus
US20220081178A1 (en) * 2012-10-19 2022-03-17 Cryovac, Llc Apparatus and method for vacuum skin packaging of a product
US11311280B2 (en) 2015-12-15 2022-04-26 Vivasure Medical Limited Arteriotomy closure apparatus with slotted shoe for advantageous pressure distribution
USD954253S1 (en) * 2019-04-30 2022-06-07 West Pharma. Services IL, Ltd. Liquid transfer device
US11357486B2 (en) 2009-12-30 2022-06-14 Vivasure Medical Limited Closure system and uses thereof
USD956958S1 (en) 2020-07-13 2022-07-05 West Pharma. Services IL, Ltd. Liquid transfer device
US11642285B2 (en) 2017-09-29 2023-05-09 West Pharma. Services IL, Ltd. Dual vial adapter assemblages including twin vented female vial adapters
CN116586924A (en) * 2023-07-17 2023-08-15 浙江一益医疗器械有限公司 Stainless steel needle tube with needle tip five-inclined-plane structure and preparation process thereof
US11793942B2 (en) 2014-12-11 2023-10-24 Facet Technologies, Llc Needle with multi-bevel tip geometry
US11918542B2 (en) 2020-01-31 2024-03-05 West Pharma. Services IL, Ltd. Liquid transfer device

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Publication number Priority date Publication date Assignee Title
FR453877A (en) * 1912-04-15 1913-06-18 Raoul Robert Bayeux Needle for hypodermic injections
FR739717A (en) * 1932-07-06 1933-01-16 Steenbrugghe & Breton Rotary drive punch needle
GB466002A (en) * 1936-10-03 1937-05-20 Selwyn Henry Winter An improved hypodermic needle
US2137132A (en) * 1937-09-17 1938-11-15 Kenneth L Cooley Duplex needle
US2409979A (en) * 1946-03-14 1946-10-22 Ralph L Huber Hypodermic needle

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR453877A (en) * 1912-04-15 1913-06-18 Raoul Robert Bayeux Needle for hypodermic injections
FR739717A (en) * 1932-07-06 1933-01-16 Steenbrugghe & Breton Rotary drive punch needle
GB466002A (en) * 1936-10-03 1937-05-20 Selwyn Henry Winter An improved hypodermic needle
US2137132A (en) * 1937-09-17 1938-11-15 Kenneth L Cooley Duplex needle
US2409979A (en) * 1946-03-14 1946-10-22 Ralph L Huber Hypodermic needle

Cited By (86)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2711733A (en) * 1951-08-10 1955-06-28 Jr George W Jacoby Hypodermic needle
US2728342A (en) * 1952-04-10 1955-12-27 Ohio Commw Eng Co Hollow filling and/or transfusion needle
US2728314A (en) * 1952-05-28 1955-12-27 Ideal Toy Corp Apparatus for inserting hair into a doll's head
US3071135A (en) * 1960-01-27 1963-01-01 Mfg Process Lab Inc Hollow needle
US3308822A (en) * 1964-04-02 1967-03-14 Loretta Fontano Hypodermic needle
US3448740A (en) * 1966-06-24 1969-06-10 Frank H J Figge Nonheel shaving hypodermic needle
US3893445A (en) * 1974-01-09 1975-07-08 Becton Dickinson Co Bone marrow biopsy instrument
US4020837A (en) * 1975-11-04 1977-05-03 Pharmaco, Inc. (Entire) Hollow piercing tip for vial stoppers
JPS54168092U (en) * 1978-05-18 1979-11-27
JPS5528274Y2 (en) * 1978-05-18 1980-07-05
US4237892A (en) * 1979-02-16 1980-12-09 American Cyanamid Company Multi-beveled, v-shaped needle point
US4561445A (en) * 1983-05-25 1985-12-31 Joseph J. Berke Elongated needle electrode and method of making same
US4990135A (en) * 1989-08-29 1991-02-05 Truesdale Jr R Grant Inoculator and needle therefor
US5941899A (en) * 1995-03-03 1999-08-24 United States Surgical Corporation Channel-bodied surgical needle and method of manufacture
US5968076A (en) * 1995-03-03 1999-10-19 United States Surgical Corporation Channel-bodied surgical needle and method of manufacture
US7320683B2 (en) * 1996-06-20 2008-01-22 Becton, Dickinson And Company Multi-beveled point needle and syringe having a multi-beveled point needle
US20040030303A1 (en) * 1996-06-20 2004-02-12 Becton, Dickinson And Company Multi-beveled point needle and syringe having a multi-beveled point needle
US5752942A (en) * 1996-06-20 1998-05-19 Becton Dickinson And Company Five beveled point geometry for a hypodermic needle
AU738278B2 (en) * 1996-06-20 2001-09-13 Becton Dickinson & Company Five beveled point geometry for a hypodermic needle
EP1281411A1 (en) 1996-06-20 2003-02-05 Becton, Dickinson and Company A five beveled point geometry for a hypodermic needle
EP0819442A1 (en) * 1996-06-20 1998-01-21 Becton, Dickinson and Company A five beveled point geometry for a hypodermic needle
AU766720B2 (en) * 1996-06-20 2003-10-23 Becton Dickinson & Company Five beveled point geometry for a hypodermic needle
US7468055B2 (en) * 1996-06-20 2008-12-23 Becton Dickinson And Company Multi-beveled point needle and syringe having a multi-beveled point needle
US20040111066A1 (en) * 1996-06-20 2004-06-10 Becton, Dickinson And Company Mult-beveled point needle and syringe having a multi-beveled point needle
FR2757405A1 (en) * 1996-12-23 1998-06-26 Vermed Needle which prevents coring of human tissue
US6517523B1 (en) * 1999-03-15 2003-02-11 Kaneko Kogyo Inc. Needle for injection syringe and method for manufacturing the same
US20040260203A1 (en) * 2001-12-12 2004-12-23 Arkray Inc. Method and implement for opening hole in soft material
US7776023B2 (en) 2001-12-12 2010-08-17 Arkray, Inc. Method and implement for opening hole in soft material
US20090171246A1 (en) * 2001-12-12 2009-07-02 Arkray Inc. Method and Implement for Opening Hole in Soft Material
EP1532996A1 (en) 2003-11-20 2005-05-25 Novo Nordisk A/S Non grinded needle tip-geometry for an injection needle
US7645268B2 (en) * 2004-03-25 2010-01-12 Boston Scientific Scimed, Inc. Needles and methods of using same
US20050215977A1 (en) * 2004-03-25 2005-09-29 Uschold John E Needles and methods of using same
US20100222796A1 (en) * 2005-04-29 2010-09-02 Vivasure Medical Ltd. Interventional medical closure device
EP2260770A3 (en) * 2005-04-29 2011-11-02 Zerusa Limited An interventional medical closure device
US8906050B2 (en) 2005-04-29 2014-12-09 Vivasure Medical Limited Interventional medical closure device
GB2446109A (en) * 2005-11-30 2008-07-30 Gene E Myers Entpr Inc Method and apparatus for contemporaneous formation of a body structure opening and homologous pedicle
WO2007065119A3 (en) * 2005-11-30 2007-11-01 Gene E Myers Entpr Inc Method and apparatus for contemporaneous formation of a body structure opening and homologous pedicle
WO2007065119A2 (en) * 2005-11-30 2007-06-07 Gene E. Myers Enterprises, Inc. Method and apparatus for contemporaneous formation of a body structure opening and homologous pedicle
US20070123935A1 (en) * 2005-11-30 2007-05-31 Myers Gene E Method and apparatus for contemporaneous formation of a body structure opening and homologous pedicle
US9610070B2 (en) 2007-06-15 2017-04-04 Vivasure Medical Limited Closure device
US11357486B2 (en) 2009-12-30 2022-06-14 Vivasure Medical Limited Closure system and uses thereof
US9060751B2 (en) 2010-12-30 2015-06-23 Vivasure Medical Limited Surgical closure systems and methods
US9572558B2 (en) 2012-02-29 2017-02-21 Vivasure Medical Limited Devices and methods for delivering implants for percutaneous perforation closure
US9662099B2 (en) 2012-02-29 2017-05-30 Vivasure Medical Limited Percutaneous perforation closure systems, devices, and methods
US9737286B2 (en) 2012-02-29 2017-08-22 Vivasure Medical Limited Implants and methods for percutaneous perforation closure
US10966698B2 (en) 2012-02-29 2021-04-06 Vivasure Medical Limited Implants and methods for percutaneous perforation closure
US10299990B2 (en) 2012-08-26 2019-05-28 West Pharma. Services IL, Ltd. Liquid drug transfer devices
US9839580B2 (en) 2012-08-26 2017-12-12 Medimop Medical Projects, Ltd. Liquid drug transfer devices
US20220081178A1 (en) * 2012-10-19 2022-03-17 Cryovac, Llc Apparatus and method for vacuum skin packaging of a product
WO2014077677A1 (en) 2012-11-13 2014-05-22 Ambro B.V. Micro needle for transporting fluid across or into a biological barrier and method for producing such a micro needle
US9850013B2 (en) 2013-03-15 2017-12-26 Vivasure Medical Limited Loading devices and methods for percutaneous perforation closure systems
US9801786B2 (en) 2013-04-14 2017-10-31 Medimop Medical Projects Ltd. Drug container closure for mounting on open-topped drug container to form drug reconstitution assemblage for use with needleless syringe
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