US2151418A - Powder applicator - Google Patents

Powder applicator Download PDF

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Publication number
US2151418A
US2151418A US142154A US14215437A US2151418A US 2151418 A US2151418 A US 2151418A US 142154 A US142154 A US 142154A US 14215437 A US14215437 A US 14215437A US 2151418 A US2151418 A US 2151418A
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Prior art keywords
cartridge
chamber
powder
insertible
head
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Expired - Lifetime
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US142154A
Inventor
Bolte Brown
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Scott & Bowne
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Scott & Bowne
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Priority to US142154A priority Critical patent/US2151418A/en
Priority to GB14192/38A priority patent/GB501564A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M13/00Insufflators for therapeutic or disinfectant purposes, i.e. devices for blowing a gas, powder or vapour into the body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0028Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0028Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/003Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
    • A61M15/0033Details of the piercing or cutting means
    • A61M15/0035Piercing means
    • A61M15/0036Piercing means hollow piercing means
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B05SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05BSPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B11/00Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
    • B05B11/01Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use characterised by the means producing the flow
    • B05B11/06Gas or vapour producing the flow, e.g. from a compressible bulb or air pump
    • B05B11/062Gas or vapour producing the flow, e.g. from a compressible bulb or air pump designed for spraying particulate material
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00Special media to be introduced, removed or treated
    • A61M2202/06Solids
    • A61M2202/064Powder
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/07General characteristics of the apparatus having air pumping means
    • A61M2205/071General characteristics of the apparatus having air pumping means hand operated
    • A61M2205/075Bulb type

Definitions

  • This invention relates to new and useful improvements in powder applicators particularly of the type employed for applying powder to the interior surfaces or cavities of the body.
  • the powder although merchandised in closed containers in the form of cartridges which are placed in the device, all such cartridges must have their ends opened or removed before insertion into the device. This requires compression of the charge by the fingers of the user and exposes the powder to contamination.
  • the powder is merchandised in closed cartridge-like containers which are placed in the device in their closed position, the cartridges being automatically opened when the device is assembled for use.
  • Still a further object of the invention resides in a novel form of powder cartridge which lends itself readily to automatic opening after it has been placed in position in the device.
  • Figure 1 is a view in elevation of a device constructed in accordance with the present invention
  • Figure. 2 is a fragmentary longitudinal sectional view of the insertible head section of the device, the view being on a slightly enlarged scale,
  • FIG. 3 is a detail sectional view taken substantially on the line 3-3 of Figure 2,
  • Figure 4 is a fragmentary longitudinal sectional view illustratingthe manner in which the device operates
  • Figure 5 is a perspective view illustrating the improved powder cartridge
  • Figure 6 is a perspective view of the body portion of the cartridge
  • Figure '7 is a plan view of the cartridge wrapper, and;
  • Figure 8 is a detail longitudinal sectional view illustrating a slightly modified form of insertible head.
  • the device includes an insertible head I ll from which projects a stem ll, preferably curved, and I2 designates a pressure producing device, preferably in the form of a conventional compressible bulb.
  • the insertible head comprises two members [4 and I6 and the stem H- is illustrated as an integral extension of the member M of the in sertible head.
  • the twomembers I 4 and I6 are separably connected together by a threaded connection l8 and each is hollowed out to provide, when threaded together, an insertible head having a cartridge receiving recess 20.
  • the cartridge consists of a hollow body portion 22 having its ends open and preferably of cylindrical form.
  • This body portion may be formed from any suitable material but I prefer to employ paper, cardboard or some similar material from which to form it.
  • the reference character 24 designates a wrapper for enclosing the cartridge body portion and for closing the ends thereof.
  • This wrapper is of a length sufiicient to pass around the cartridge body at least once and of a width greater than the length of the cartridge body to provide portions 25 which may be tucked into the open ends of the body portion to close the same.
  • One end of the wrapper is cut at an angle as at 28 and this end may be provided with a suitable adhesive designated 30.
  • the hollow cartridge is filled with powder, after which it is enclosed in the wrapper 24, the portions 25 of the wrapper being tucked into the open ends of the cartridge body to form the complete wrapper shown in Figure 5.
  • the end wall of the recess in the member I4 is so formed as to provide a conical projection 34 which extends into the cartridge chamber.
  • This construction provides a shoulder 36 with which the adjacent end of the body portion of the cartridge is adapted to engage when the cartridge is in its operative position. The end of the body portion of the cartridge is forced into engagemerit with the shoulder 36 by reason of th engagernent of the opposite end of the body of the cartridge with a shoulder 38 at the end wall of the recess of the member l6 of the insertible head it), when the two members I4 and I6 of the insertible head 10 are threaded together.
  • the member I6 of the insertible head forms the discharge member thereof and has a discharge passage extending therethrough, the member I4 having an inlet passage 40 which leads into the cartridge receptacle 20.
  • the discharger passage of the member l6 has a contracted neck portion 42 which is spaced slightly from the shoulder 38 to provide an intervening chamber 44,
  • the chamber provides a space into which the tucked in portion of the wrapper which closes the adjacent end of the cartridge body may extend as the powder is subjected to pressure to force it from the device, as is illustrated at 26' in Figure 4 of the drawing.
  • the contracted neck portion 42 serves to pre-' vent too rapid movement of the powder through the discharge passage of the member l6, thereby insuring that the powder is discharged more in the form of a continuous spray than a single blast. This is also aided by reason of the projection of the adjacent tucked in portion of the cartridge wrapper into the chamber 44 under very light pressure upon the powder, therefore permitting movement of the powder before sufficient pressure is built up to discharge the powder in a single blast-like charge.
  • the discharge passage is flared outwardly as at 48 to provide a relatively large discharge opening 50 which permits the powder to discharge in a spray-like form as illustrated in Figure 4 of the drawing.
  • the form of the invention illustrated in Figure 8 of the drawing provides for opening both ends of the cartridge when the two members of the insertible head are threaded together and to this end, the end wall of the recess in the member I6 is so constructed as toprovide a conically shaped projection 60, which forces the adjacent tucked in portion of the wrapper inwardly of the cartridge body as the two members of the insertible head are threaded together, thus automatically opening both ends of the cartridge as illustrated in Figure 8, when the device is assembled for use.
  • an insertible head comprising two hollow members separably connected together to provide a cartridge receiving chamber, a projection extending into said chamber from one end thereof, the other end of the chamber having a discharge passage contracted intermediate its ends to provide an intervening chamber immediately adjacent the end of the cartridge chamber into which the adjacent end of a cartridge may expand, and a shoulder at each end of the. cartridge chamber for engagement by the cartridge to prevent endwise movement of a cartridge in the cartridge chamber.
  • an insertible head member for body cavities com-' prising two hollow members each havng a longitudinally extending passage, means for securingv said hollow members together to combine in providing a cartridge receiving chamber having an inlet passage and an outlet passage, means adapted to hold a cartridge against longitudinal movement in said chamber when said members are secured together in their operative position, and means for rupturing one end of said cartridge during relative movement of the members to their connected position,
  • an insertible head member for body cavities comprising two hollow members separably connected together, said hollow members when connected together providing a chamber for receiving a cartridge having disruptible ends, each end of said chamber comprising a longitudinally extending conical projection having a base substantially coextensive with the end of the chamber for engaging and rupturing the ends of a cartridge placed in the chamber, said projections having central passages communicating with the chamber, the passage in one of the projections being utilized for discharging the contents of. the cartridge by fluid pressure admitted through the passage in the other of the projections.
  • an insertible head comprising two hollow members, means for securing said members together to provide a cartridge receiving chamber having inlet and outlet passages, said outlet passage being flared, means for holding a cartridge in the chamber when said members are secured together in their operative position and means extending into the chamber from the inlet passage for rupturing one of the ends of the cartridge when the members are secured together.

Description

March 21, 1939. B. BOLTE POWDER APPLICATOR Filed May 12, 1957 LI n mm Q j RN BROWN 504 75 6%? INVENT OR.
ATTORNE Y3.
WITNESS;
Patented Mar. 21, 1939 PATENT OFFICE POWDER APPLICATOR Brown Bolt, Orange, N. J., assignor to Scott & Bowne, Bloomfield, N. J., a corporation of New Jersey Application May 12, 1937, Serial No. 142,154
4 Claims.
This invention relates to new and useful improvements in powder applicators particularly of the type employed for applying powder to the interior surfaces or cavities of the body.
I am aware of the fact that such devices have heretofore been patented, but all such devices with'which I am familiar have certain disadvantages which the device of the present invention overcomes.
It is the primary object of the present invention to improve the construction of such devices in such a manner as to render them more efficient, simple in operation, and of a more sanitary character. I
One serious "disadvantage of all such devices with which I am familiar is that the powder is discharged in a single blast-like action instead of a continuous spray or stream, and it is an object of this invention so to construct the device that this serious disadvantage is overcome.
Further, in all such devices with which I am familiar, the powder, although merchandised in closed containers in the form of cartridges which are placed in the device, all such cartridges must have their ends opened or removed before insertion into the device. This requires compression of the charge by the fingers of the user and exposes the powder to contamination.
In the present device the powder is merchandised in closed cartridge-like containers which are placed in the device in their closed position, the cartridges being automatically opened when the device is assembled for use.
Still a further object of the invention resides in a novel form of powder cartridge which lends itself readily to automatic opening after it has been placed in position in the device.
Other objects of the invention will appear as the nature ofthe invention is better understood, and reference will be had to the following specification and claims and to the accompanying drawing, wherein,
Figure 1 is a view in elevation of a device constructed in accordance with the present invention,
Figure. 2 is a fragmentary longitudinal sectional view of the insertible head section of the device, the view being on a slightly enlarged scale,
Figure 3 is a detail sectional view taken substantially on the line 3-3 of Figure 2,
Figure 4 is a fragmentary longitudinal sectional view illustratingthe manner in which the device operates,
Figure 5 is a perspective view illustrating the improved powder cartridge,
Figure 6 is a perspective view of the body portion of the cartridge,
Figure '7 is a plan view of the cartridge wrapper, and;
Figure 8 is a detail longitudinal sectional view illustrating a slightly modified form of insertible head.
Referring more particularly to the drawing, the device includes an insertible head I ll from which projects a stem ll, preferably curved, and I2 designates a pressure producing device, preferably in the form of a conventional compressible bulb.
In both of the illustrated forms of the invention the insertible head comprises two members [4 and I6 and the stem H- is illustrated as an integral extension of the member M of the in sertible head. The twomembers I 4 and I6 are separably connected together by a threaded connection l8 and each is hollowed out to provide, when threaded together, an insertible head having a cartridge receiving recess 20.
In Figures 5 through 7 of the drawing I have illustrated one form of a new and improved cartridge for use in connection with my device, and I will not proceed to describe the same.
The cartridge consists of a hollow body portion 22 having its ends open and preferably of cylindrical form. This body portion may be formed from any suitable material but I prefer to employ paper, cardboard or some similar material from which to form it. The reference character 24 designates a wrapper for enclosing the cartridge body portion and for closing the ends thereof. This wrapper is of a length sufiicient to pass around the cartridge body at least once and of a width greater than the length of the cartridge body to provide portions 25 which may be tucked into the open ends of the body portion to close the same. One end of the wrapper is cut at an angle as at 28 and this end may be provided with a suitable adhesive designated 30.
The hollow cartridge is filled with powder, after which it is enclosed in the wrapper 24, the portions 25 of the wrapper being tucked into the open ends of the cartridge body to form the complete wrapper shown in Figure 5.
It is obvious that if such a cartridge were inserted in an insertible head of ordinary construction, the pressure produced by such a device as the bulb [2 would not be sufiicient to effect a discharge of the contents of the cartridge, and I therefore provide means for rupturing the cartridge wrapper in order that the contents of the cartridge may be discharged by such pressure as the bulb I2 is capable of producing. This means for rupturing the cartridge is so incorporated in the device that the cartridge may be placed in the insertible head before the cartridge has been opened, the rupturing operation being accomplished automatically upon operatively connecting together the two members ofthe insertible head l0.
The foregoing result is accomplished in the following manner:
The end wall of the recess in the member I4 is so formed as to provide a conical projection 34 which extends into the cartridge chamber. This construction provides a shoulder 36 with which the adjacent end of the body portion of the cartridge is adapted to engage when the cartridge is in its operative position. The end of the body portion of the cartridge is forced into engagemerit with the shoulder 36 by reason of th engagernent of the opposite end of the body of the cartridge with a shoulder 38 at the end wall of the recess of the member l6 of the insertible head it), when the two members I4 and I6 of the insertible head 10 are threaded together.
Threading together of the two members !4 and I6 forces the projection 34 inwardly of the adjacent end of the cartridge, forcing the tucked in portion 26 thereof inwardly of the cartridge to open the end thereof.
The member I6 of the insertible head forms the discharge member thereof and has a discharge passage extending therethrough, the member I4 having an inlet passage 40 which leads into the cartridge receptacle 20.
The discharger passage of the member l6 has a contracted neck portion 42 which is spaced slightly from the shoulder 38 to provide an intervening chamber 44,
The chamber provides a space into which the tucked in portion of the wrapper which closes the adjacent end of the cartridge body may extend as the powder is subjected to pressure to force it from the device, as is illustrated at 26' in Figure 4 of the drawing.
The contracted neck portion 42 serves to pre-' vent too rapid movement of the powder through the discharge passage of the member l6, thereby insuring that the powder is discharged more in the form of a continuous spray than a single blast. This is also aided by reason of the projection of the adjacent tucked in portion of the cartridge wrapper into the chamber 44 under very light pressure upon the powder, therefore permitting movement of the powder before sufficient pressure is built up to discharge the powder in a single blast-like charge.
From the contracted neck portion 42, the discharge passage is flared outwardly as at 48 to provide a relatively large discharge opening 50 which permits the powder to discharge in a spray-like form as illustrated in Figure 4 of the drawing.
The form of the invention illustrated in Figure 8 of the drawing provides for opening both ends of the cartridge when the two members of the insertible head are threaded together and to this end, the end wall of the recess in the member I6 is so constructed as toprovide a conically shaped projection 60, which forces the adjacent tucked in portion of the wrapper inwardly of the cartridge body as the two members of the insertible head are threaded together, thus automatically opening both ends of the cartridge as illustrated in Figure 8, when the device is assembled for use.
From the foregoing it will be apparent that the present invention provides a new and novel construction by which each of the recited objects are accomplished, and while the invention has been herein illustrated in its preferred forms, it is to be understood that it is not to be limited to the specific constructon herein set forth, but may be embodied in other forms within the scope of the appended claims.
Having thus describe-d the invention, What is claimed as new, is:
1. In a device of the character described, an insertible head comprising two hollow members separably connected together to providea cartridge receiving chamber, a projection extending into said chamber from one end thereof, the other end of the chamber having a discharge passage contracted intermediate its ends to provide an intervening chamber immediately adjacent the end of the cartridge chamber into which the adjacent end of a cartridge may expand, and a shoulder at each end of the. cartridge chamber for engagement by the cartridge to prevent endwise movement of a cartridge in the cartridge chamber.
2. In a device of the character described, an insertible head member for body cavities com-' prising two hollow members each havng a longitudinally extending passage, means for securingv said hollow members together to combine in providing a cartridge receiving chamber having an inlet passage and an outlet passage, means adapted to hold a cartridge against longitudinal movement in said chamber when said members are secured together in their operative position, and means for rupturing one end of said cartridge during relative movement of the members to their connected position,
3. In a device of the character described, an insertible head member for body cavities comprising two hollow members separably connected together, said hollow members when connected together providing a chamber for receiving a cartridge having disruptible ends, each end of said chamber comprising a longitudinally extending conical projection having a base substantially coextensive with the end of the chamber for engaging and rupturing the ends of a cartridge placed in the chamber, said projections having central passages communicating with the chamber, the passage in one of the projections being utilized for discharging the contents of. the cartridge by fluid pressure admitted through the passage in the other of the projections.
4. In a device of the character described, an insertible head comprising two hollow members, means for securing said members together to provide a cartridge receiving chamber having inlet and outlet passages, said outlet passage being flared, means for holding a cartridge in the chamber when said members are secured together in their operative position and means extending into the chamber from the inlet passage for rupturing one of the ends of the cartridge when the members are secured together.
BROWN BOLTF
US142154A 1937-05-12 1937-05-12 Powder applicator Expired - Lifetime US2151418A (en)

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Cited By (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2501279A (en) * 1946-01-17 1950-03-21 Kark Charles Lazar Means for spraying or projecting powder
US2515193A (en) * 1945-11-19 1950-07-18 Frank R Chester Powder sprayer
US2908244A (en) * 1957-03-18 1959-10-13 Cecil B Clark Defensive device
US2946332A (en) * 1957-12-23 1960-07-26 Nysco Lab Inc Insufflator
US3235126A (en) * 1964-09-21 1966-02-15 Pace Inc Aerosol spray device
US3308818A (en) * 1964-07-24 1967-03-14 Eugene V Rutkowski Injection cartridge
US4307823A (en) * 1980-01-21 1981-12-29 Diamond Crystal Salt Company Powder dispenser
US5273531A (en) * 1992-09-21 1993-12-28 Knoepfler Dennis J Method of applying thrombic powder in laparoscopic procedures
US5683361A (en) * 1991-12-10 1997-11-04 Novo Nordisk A/S Disposable dispenser for powder
US6168587B1 (en) 1993-04-08 2001-01-02 Powderject Research Limited Needleless syringe using supersonic gas flow for particle delivery
EP1321160A3 (en) * 2001-12-21 2004-06-23 Ing. Erich Pfeiffer GmbH & Co. KG Method and dispenser for mixing and delivering of substances
US20050000518A1 (en) * 2003-04-09 2005-01-06 Nektar Therapeutics Aerosolization apparatus with capsule puncture alignment guide
US20050143675A1 (en) * 2003-12-31 2005-06-30 Home Diagnostics, Inc. Integrated diagnostic test system
US20060084910A1 (en) * 2004-10-15 2006-04-20 David Hoffman Drug delivery sheath
US20080300535A1 (en) * 2001-07-26 2008-12-04 Powderject Research Limited Particle cassette, method and kit therefor
WO2010070333A2 (en) 2008-12-15 2010-06-24 Profibrix B.V. Powder delivery device
US20100160897A1 (en) * 2008-12-23 2010-06-24 Ducharme Richard W Apparatus and Methods for Containing and Delivering Therapeutic Agents
US20100234826A1 (en) * 2007-05-08 2010-09-16 Cyto-Biotics, L.L.C. Medicament Dispensing Devices and Methods
US20110066132A1 (en) * 2009-09-17 2011-03-17 Xin Ji Internal dry powder delivery system and method thereof
US8118777B2 (en) 2009-05-29 2012-02-21 Cook Medical Technologies Llc Systems and methods for delivering therapeutic agents
US20130046278A1 (en) * 2010-01-15 2013-02-21 Xin Ji Internal Dry Powder Delivery System and Method Thereof
US8575132B2 (en) 2007-08-09 2013-11-05 Xin Ji Modified starch material of biocompatible hemostasis
US20140100551A1 (en) * 2011-06-01 2014-04-10 Catheasy Vasteras Ab Flushing device and a catheter kit comprising a flushing device
US20140308625A1 (en) * 2011-12-23 2014-10-16 Koninklijke Philips N.V. Device for delivery of a tooth whitening agent
US8920364B2 (en) 2013-02-28 2014-12-30 Medtronic Xomed, Inc. Biomaterial delivery device
US9101744B2 (en) 2009-05-29 2015-08-11 Cook Medical Technologies Llc Systems and methods for delivering therapeutic agents
EP2654863B1 (en) 2010-12-23 2016-09-21 ProFibrix BV Powder delivery device
US9839772B2 (en) 2008-05-06 2017-12-12 Cook Medical Technologies Llc Apparatus and methods for delivering therapeutic agents
US9867931B2 (en) 2013-10-02 2018-01-16 Cook Medical Technologies Llc Therapeutic agents for delivery using a catheter and pressure source
US10314937B2 (en) 2014-09-18 2019-06-11 Endoclot Plus Co., Ltd. Biocompatible hemostatic product and preparation method thereof
US11213615B2 (en) 2017-02-28 2022-01-04 EndoClot Plus Co.. Ltd Composition for submucosal injection, reagent combination, and applications thereof
US11406771B2 (en) 2017-01-10 2022-08-09 Boston Scientific Scimed, Inc. Apparatuses and methods for delivering powdered agents
US11433223B2 (en) 2016-07-01 2022-09-06 Boston Scientific Scimed, Inc. Delivery devices and methods
US11642281B2 (en) 2018-10-02 2023-05-09 Boston Scientific Scimed, Inc. Endoscopic medical device for dispensing materials and method of use
US11701448B2 (en) 2018-01-12 2023-07-18 Boston Scientific Scimed, Inc. Powder for achieving hemostasis
US11766546B2 (en) 2018-01-31 2023-09-26 Boston Scientific Scimed, Inc. Apparatuses and methods for delivering powdered agents
US11833539B2 (en) 2018-10-02 2023-12-05 Boston Scientific Scimed, Inc. Fluidization devices and methods of use
US11918780B2 (en) 2020-12-01 2024-03-05 Boston Scientific Scimed, Inc. Agent administering medical device

Families Citing this family (2)

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Publication number Priority date Publication date Assignee Title
DE1047385B (en) * 1952-03-08 1958-12-24 Armour & Co Powder atomizer with an exchangeable powder container
GB0320171D0 (en) 2003-08-28 2003-10-01 Optinose As Delivery devices

Cited By (60)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2515193A (en) * 1945-11-19 1950-07-18 Frank R Chester Powder sprayer
US2501279A (en) * 1946-01-17 1950-03-21 Kark Charles Lazar Means for spraying or projecting powder
US2908244A (en) * 1957-03-18 1959-10-13 Cecil B Clark Defensive device
US2946332A (en) * 1957-12-23 1960-07-26 Nysco Lab Inc Insufflator
US3308818A (en) * 1964-07-24 1967-03-14 Eugene V Rutkowski Injection cartridge
US3235126A (en) * 1964-09-21 1966-02-15 Pace Inc Aerosol spray device
US4307823A (en) * 1980-01-21 1981-12-29 Diamond Crystal Salt Company Powder dispenser
US5683361A (en) * 1991-12-10 1997-11-04 Novo Nordisk A/S Disposable dispenser for powder
US5273531A (en) * 1992-09-21 1993-12-28 Knoepfler Dennis J Method of applying thrombic powder in laparoscopic procedures
US6168587B1 (en) 1993-04-08 2001-01-02 Powderject Research Limited Needleless syringe using supersonic gas flow for particle delivery
US8061006B2 (en) 2001-07-26 2011-11-22 Powderject Research Limited Particle cassette, method and kit therefor
US20080300535A1 (en) * 2001-07-26 2008-12-04 Powderject Research Limited Particle cassette, method and kit therefor
EP1321160A3 (en) * 2001-12-21 2004-06-23 Ing. Erich Pfeiffer GmbH & Co. KG Method and dispenser for mixing and delivering of substances
US6877672B2 (en) 2001-12-21 2005-04-12 Ing. Erich Pfeiffer Gmbh Method and dispenser for mixing and discharging media
WO2004091707A3 (en) * 2003-04-09 2005-03-31 Nektar Therapeutics Aerosolization apparatus with capsule puncture alignment guide
US11484671B2 (en) 2003-04-09 2022-11-01 Bgp Products Operations Gmbh Aerosolization apparatus with capsule puncture alignment guide
US10207066B2 (en) 2003-04-09 2019-02-19 Bgp Products Operations Gmbh Aerosolization apparatus with capsule puncture alignment guide
US20050000518A1 (en) * 2003-04-09 2005-01-06 Nektar Therapeutics Aerosolization apparatus with capsule puncture alignment guide
US20050143675A1 (en) * 2003-12-31 2005-06-30 Home Diagnostics, Inc. Integrated diagnostic test system
US20060084910A1 (en) * 2004-10-15 2006-04-20 David Hoffman Drug delivery sheath
US8771257B2 (en) * 2004-10-15 2014-07-08 Boston Scientific Scimed, Inc. Drug delivery sheath
US20100234826A1 (en) * 2007-05-08 2010-09-16 Cyto-Biotics, L.L.C. Medicament Dispensing Devices and Methods
US8465463B2 (en) 2007-05-08 2013-06-18 Cyto-Biotics, Llc Medicament dispensing devices and methods
US8157772B2 (en) 2007-05-08 2012-04-17 Cyto-Biotics, Llc Medicament dispensing devices and methods
US10076590B2 (en) 2007-08-09 2018-09-18 Xin Ji Modified starch material of biocompatible hemostasis
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