US20140350518A1 - Syringe extrusion accessory - Google Patents
Syringe extrusion accessory Download PDFInfo
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- US20140350518A1 US20140350518A1 US14/284,285 US201414284285A US2014350518A1 US 20140350518 A1 US20140350518 A1 US 20140350518A1 US 201414284285 A US201414284285 A US 201414284285A US 2014350518 A1 US2014350518 A1 US 2014350518A1
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- Prior art keywords
- syringe
- handle
- accessory
- prawl
- plunger
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/3129—Syringe barrels
- A61M5/3137—Specially designed finger grip means, e.g. for easy manipulation of the syringe rod
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31533—Dosing mechanisms, i.e. setting a dose
- A61M5/31545—Setting modes for dosing
- A61M5/31548—Mechanically operated dose setting member
- A61M5/31555—Mechanically operated dose setting member by purely axial movement of dose setting member, e.g. during setting or filling of a syringe
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31533—Dosing mechanisms, i.e. setting a dose
- A61M5/31545—Setting modes for dosing
- A61M5/31548—Mechanically operated dose setting member
- A61M5/31556—Accuracy improving means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
- A61M5/31576—Constructional features or modes of drive mechanisms for piston rods
- A61M5/31578—Constructional features or modes of drive mechanisms for piston rods based on axial translation, i.e. components directly operatively associated and axially moved with plunger rod
- A61M5/31581—Constructional features or modes of drive mechanisms for piston rods based on axial translation, i.e. components directly operatively associated and axially moved with plunger rod performed by rotationally moving or pivoting actuator operated by user, e.g. an injection lever or handle
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/50—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for preventing re-use, or for indicating if defective, used, tampered with or unsterile
- A61M5/5013—Means for blocking the piston or the fluid passageway to prevent illegal refilling of a syringe
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/3129—Syringe barrels
- A61M5/3137—Specially designed finger grip means, e.g. for easy manipulation of the syringe rod
- A61M2005/3139—Finger grips not integrally formed with the syringe barrel, e.g. using adapter with finger grips
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- Health & Medical Sciences (AREA)
- Vascular Medicine (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Dental Tools And Instruments Or Auxiliary Dental Instruments (AREA)
Abstract
Described herein are syringe extrusion accessories comprising: a handle operatively coupled to an attachment portion configured to attach to a syringe; and at least one prawl operatively coupled to the handle and configured to engage with a plunger of the syringe, wherein the syringe extrusion accessory is configured to transfer a substantially perpendicular force applied to the handle to an axial force to push the plunger and extrude a product from the syringe.
Description
- This application claims the benefit of U.S. provisional patent application No. 61/826,878, filed May 23, 2013, the entire disclosure of which is incorporated herein by reference.
- The present invention generally relates to medical injection device accessories, and more specifically relates to a medical syringe accessory designed to facilitate aliquot dosing.
- The ability to accurately assess correct injection dosage is most commonly associated with visual cues. For example, volumetric marks already come printed or etched on the side of conventional syringe bodies, and this remains the most common form of measurement. A practitioner injects a certain amount of a substance, such as a drug, by verifying fluid level using these volumetric marks.
- Even more generally, a physician can intake an amount of a drug to be injected into the syringe using the volumetric marks. Then, a practitioner can simply expel the entire volume into a patient in a single plunger run. Such a full expulsion of drug removed the need to only inject a portion of a drug in a syringe. Thus, for pharmaceutical drugs, the benefits of injecting the correct dosage should not require explanation.
- However, in applications using sensitive drugs such as botulinum toxin or aesthetic soft tissue fillers, for example, hyaluronic acid-based dermal fillers such as Juvederm® XC, manufactured by Allergan, Inc., dose indication provides the practitioner with additional control over precise facial sculpting.
- Additionally, with applications like botulinum toxin, injection of multiple small, precise doses of toxin may be advantageous over injection of a large bolus of the material.
- Further, with fat grafting, injection of multiple small, precise doses of fat cell-containing material may be advantageous over injection of a single large bolus of the material. Smaller bolus injection increases retention of the injected material, possibly by providing greater vascularization of the material throughout the fat cells and improving survivability thereof. Injection of a large bolus is less likely to be retained long term as the injected fat cells are may be more prone to die, due to lack of vascularization, for example.
- Many of these injectable materials, for example, dermal fillers and fat grafting materials, are not easily extruded through standard syringes and accompanying cannula. These materials tend to provide significant resistance to be pushed through a narrow cannula. The problem is even more exacerbated by the fact that these materials are often used for detailed precision work in facial contouring and body sculpting.
- Injection devices, both manual and motorized, have been specifically developed, or at least proposed, to address these issues. Interestingly, many physicians prefer the use of manual conventional syringe injectors over electronically controlled, motorized devices. For at least this reason, there remains a need for devices (e.g., simple devices) that can be attached to a standard syringe and which provide better control over small aliquot dosing of relatively difficult to inject materials, for example, dermal fillers, fat grafting materials and the like.
- Disclosed herein are mechanical dosing accessories and/or syringe extrusion accessories configured to be attached to, coupled to, or incorporated into standard syringes. The dosing accessories are configured to provide improved mechanical advantage or leverage and dosing capability, relative to a conventional syringe alone. In some embodiments, the accessories described can be used in conjunction with conventional syringes for injection of substances. The substances or products can be highly viscous such as, but not limited to, dermal fillers or fat grafting materials.
- In one embodiment described herein are syringe extrusion accessories. The accessories can include: a handle operatively coupled to an attachment portion configured to attach to a syringe; and at least one prawl operatively coupled to the handle and configured to engage with a plunger of the syringe. The syringe extrusion accessory can be configured to transfer a substantially perpendicular force applied to the handle to an axial force to push the plunger and extrude a product from the syringe.
- Other embodiments include methods of using the syringe extrusion accessories. The methods describe extruding a product from a syringe. The methods include: applying a substantially perpendicular force to an accessory associated with the syringe thereby extruding the product from the syringe. The accessories can include a handle operatively coupled to an attachment portion configured to attach to a syringe; and at least one prawl operatively coupled to the handle and configured to engage with a plunger of the syringe. The handle can include one or more depressions configured to apply force from at least one finger.
- In some embodiments, the methods can be used with the accessory which is configured to transfer a substantially perpendicular force applied to the handle to an axial force to push the plunger and extrude the product from the syringe. The accessory can be attached to the syringe's flange by a snap fit, a friction fit, a glue, an adhesive, or a combination thereof.
- The at least one prawl described herein can include at least one claw which can be configured to engage with the syringe's plunger. The prawl can also have a sinusoidal shape.
- The accessory includes a handle which can be coupled to the attachment portion through a hinge. In other embodiments, the prawl is also coupled to the handle through a hinge. The prawl can further be attached to the handle with a spring, such as a compression spring. The accessories described herein can attach to any portion of a syringe. In some embodiments, the accessories can attach or be configured to attach to a flange associated with the syringe.
- Embodiments of the present description are illustrated by way of example, and not by way of limitation, in the figures of the accompanying drawings and in which like reference numerals refer to similar elements, wherein:
-
FIG. 1 illustrates a perspective view of a syringe and a syringe extrusion accessory as described herein. -
FIG. 2 illustrates a perspective view of a syringe with an extrusion accessory as illustrated inFIG. 1 attached thereto. -
FIG. 3 illustrates a first step in using an extrusion accessory wherein the accessory is added to the syringe and prepared for use. -
FIG. 4 illustrates a second step in using an extrusion accessory wherein a substantially perpendicular force is applied to the accessory's handle thereby applying an axial force to the syringe's plunger. -
FIG. 5 illustrates a third step in using an extrusion accessory wherein a substantially perpendicular force is applied to the accessory's handle until the prawl can no longer extend from the handle indicating the end of an injection sequence. -
FIG. 6 illustrates a reset of the extrusion accessory to extrude a further amount of substance from the syringe. - Generally described are syringe accessories such as, but not limited to mechanical dosing accessories and/or syringe extrusion accessories that can be attached to a conventional syringe and provide a transfer of perpendicular force to axial force for injection. In other embodiments, an accessory as described herein can be permanently mounted to a syringe using, for example, glue or adhesive. In still other embodiments, a syringe including an accessory as described herein can be produced as a single integrated device.
- As illustrated in
FIGS. 1-2 , anaccessory 100 as described herein can generally includehandle 102,prawl 104,attachment portion 106, afirst hinge 108 and asecond hinge 110. -
Handle 102 can optionally include afinger indentation region 112 wherein a user can apply a substantially perpendicular force to a depressed portion thereby focusing the force to a substantially predetermined point onhandle 102.Handle 102 can be configured to accept a substantially perpendicular input force and transfer that force toprawl 104. -
Prawl 104 is operably attached to handle 102 throughsecond hinge 110.Prawl 104 can have a generally sinusoidal shape having afirst end 114 terminating atsecond hinge 110 and second end 116 terminating at one ormore claws 118.First end 114 can be curved toward theproximal end 130 ofsyringe 122 when fully extended in use thereby achieving the translation of force provided by the accessories. Second end 116 can be curved toward the distal end ofsyringe 122 when fully extended in use. -
Prawl 104 can be operably configured to move one ormore claws 118 in generallyaxial direction 120.Prawl 104 can include one, two, three, four, five, six, seven, eight, nine, ten, eleven, twelve, 13, 14, 15, 16, 17, 18, 19, 20, or more claws. As such, based on substantially perpendicular movement ofhandle 102,claws 118 can in turn be moved inaxial direction 120 throughsecond hinge 110. - Further, handle 102 is operably connected to
attachment portion 106 throughfirst hinge 108.Attachment portion 106 is configured to allow attachment ofaccessory 100 tosyringe 122. In one embodiment,accessory 100 can be attached tosyringe 122 atflange 124.Attachment portion 106 can be shaped to at least partially engageflange 124. In some embodiments,attachment portion 106 can engage between about 20% and about 80%, between about 30% and about 60%, between about 40% and about 60%, between about 50% and about 70%, or between about 60% and about 80% offlange 124.Attachment portion 106 can engage withflange 124 using a friction fit, a locking fit whereattachment portion 106 includes locking features that snap and lock once the two parts are engaged, or a glue engagement whereinattachment portion 106 andflange 124 are glued together. - Substantially perpendicular force applied to handle 102 can be translated to force in
axial direction 120.Claws 118 can engageplunger 126 and provide an axial force thereby drivingplunger head 128 towardproximal end 130 ofsyringe 122. - Substantially perpendicular force can be applied at an
angle 132 which is substantially perpendicular tosyringe 122.Angle 132 can be about 1 degree, about 5 degrees, about 10 degrees, about 15 degrees, about 20 degrees, about 25 degrees, less than about 5 degrees, less than about 10 degrees, less than about 15 degrees, between about 1 degree and about 10 degrees, between about 1 degree and about 20 degrees, or between about 5 degrees and about 25 degrees. - This substantially perpendicular force can replace axial forces that typically must be applied to
plunger finger surface 134. With highly viscous materials such as dermal fillers and fat grafting substances, substantial axial forces must be applied in order to extrude these materials from a needle or other delivery device attached toluer tip 136 or other attachment interface. This need to apply a substantial force toplunger finger surface 134 requires a user to balance applying axial forces to the syringe with resisting axial forces of a needle into the tissue. - In some embodiments,
luer tip 136 or other attachment interface can be configured to attach to a cannula or needle which is suitable for introducing contents ofsyringe 122 into a target region of a patient for tissue bulking, augmentation or reconstructive purposes. - In other embodiments,
luer tip 136 or other attachment interface can be configured to attach to flexible tubing or a conduit which is suitable for introducing contents ofsyringe 122 into a target region of a patient for tissue bulking, augmentation or reconstructive purposes. Such embodiments may allow for enhanced flexibility and ergonomic grip of a cannula or a needle. - A cannula or a needle as used herein can be a 10, 12, 14, 16, 18, 20, 22 up to 33 gauge, or other gauges. In some embodiments, the needle gauge may be one suitable for fat grafting or dermal filler purposes. In one embodiment, the needle gauge is between 10 and 33. The length of a needle can be any appropriate length known in the art. In one embodiment, the needle length is about 1/16 inch to about 3 inches, more generally about 1/16 inch to about 2 inches. A cannula or a needle may be blunt or sharp tipped.
-
Prawl 104 can be configured to engage with a given plunger style. Plungers can have various shapes forstem portion 138. For example, as illustrated in the Figures, stem 138 includesvertical appendage 140 andhorizontal appendage 142. Thus, in one embodiment,prawl 104 can be split at second end 116 thereby straddlingvertical appendage 140 without touching it and engaging both sides ofhorizontal appendage 142. - In other embodiments,
stem portion 138 may have a cylindrical shape or circular cross-section. In such embodiments,prawl 104 can have a single second end 116 or an un-split second end. This single second end 116 can engagestem portion 138 along its cylindrical surface. - Various other stem shapes can be used and skilled artisans will understand how to modify
prawl 104 to engage these types of plungers and translate substantially perpendicular force to axial force on the plunger. - In some embodiments,
spring 144 can be provided to couple prawl 104 to handle 102 as illustrated inFIGS. 3-6 .Spring 144 can provide a resistive or compressive force ashandle 102 is depressed. When handle 102 is disengaged, thereby disengagingprawl 104 fromplunger 126,spring 144 can compress thereby pullingprawl 104 towardhandle 102 as illustrated inFIG. 6 thereby “re-setting” the device. - In some embodiments, tracks can be provided on
plunger 126 forclaws 118 to engage. For example, as illustrated inFIG. 5 , in some embodiments,tracks 146 can be located onvertical appendage 140 and/orhorizontal appendage 142. - An exemplary track system can be configured to allow
claws 118 to engage in one ormore valleys 150 betweenadjacent teeth 148. In some embodiments,teeth 148 can have a generally rounded or oval surface preventing claw leverage onto the plunger. Eachvalley 150 betweenadjacent teeth 148 can be spaced apredetermined distance 152 from thenext valley 150. - In other embodiments,
teeth 148 can be configured to have a generally wave-like shape. When a claw is engaged in avalley 150 with a long front surface and a short back surface,claws 118 can provide force against the short wall ofteeth 148. In some embodiments, anaccessory 100 can include a plunger that has tracks that can be used withaccessory 100. When a plunger is provided, the syringe plunger can be replaced with the provided plunger. - In other embodiments, a track or set of tracks can be provided to be attached to a plunger. In these embodiments, tracks can be glued to the plunger stem prior to use. In other embodiments, tracks can be snapped around a plunger stem.
- Each
valley 150 between adjacent ratchetingteeth 148 can be spaced 152 from the next valley. Eachspace 152 can be equivalent to a predetermined amount of substance ejected from the syringe. This is the case because movement of track 146 a particular distance movesplunger 126 which eventually movesplunger head 128 the same axial distance. -
Accessory 100 can be formed of metal, a polymer, or a combination thereof. In some embodiments,accessory 100 can include materials such as, but not limited to, rigid thermoplastics, thermoplastic elastomers, silicones, glass, metals, composite materials, carbons fillers, or any combination thereof. - The accessories described herein can allow an operator to easily inject viscous substances or materials through any size needle known in the art by applying substantially perpendicular force to the handle. The accessories make the syringe easy to hold, manipulate and operate with one hand, and in some cases adjust easily with the operator's opposing hand. The accessories can allow the operator to precisely control the injection speed (or extrusion rate) being injected. The accessories can also allow an operator to still see the graduation or volume markings on the syringe body thereby allowing an operator to visualize initial volume, volume injected and remaining volume of substance in the syringe.
- Further, the accessories described herein can have an ergonomic shape that allows the operator to hold and inject from the syringe easily. Unlike traditional syringes which do not conform to any ergonomic aspect of the hand, the present devices can have at least one ergonomic design shaped into the accessories such as
finger indentation region 112. Additionally, the present accessories can accommodate operator hands of different sizes. Hand size accommodation can be accomplished by different device sizes, position-adjustable device handles or interchangeable device handles. For example, interchangeable handles can come in various predetermined sizes or can be personalized for a particular user. - Methods of using the accessories described are also contemplated. For example, in some embodiments, an accessory is provided and attached to a syringe preferably at the
syringe flange 124 as illustrated inFIG. 3 .Spring 144 can be configured to rest handle 102 at apredetermined angle 132 relative tosyringe 122 withclaws 118 resting againstplunger stem 138. - Then, as illustrated in
FIG. 4 , force is applied to handle 102 substantially perpendicular tosyringe 122, thereby driving axial force to plunger 126 as translated byprawl 104. - When a particular spring force has been exhausted or a
stop 154 on the underside ofhandle 102 has been reached,plunger 126 will not be moved axially any further as illustrated inFIG. 5 . At this point, a full extension ofaccessory 100 has been achieved. - In other embodiments, full extension of
accessory 100 can be achieved when prawl 104 abuts handle 102 at leadingedge 162. - The force applied to move from
predetermined angle 132 illustrated inFIG. 3 to the full extension ofaccessory 100 inFIG. 5 can translate into a predetermined dose of extruded content. For example, the force can translate into about 0.1 mL, about 0.5 mL, about 1 mL, about 2 mL, about 3 mL, about 4 mL, about 5 mL, about 10 mL, about 15 mL, about 20 mL, between about 0.1 mL and about 10 mL, between about 1 mL and about 10 mL, or between about 0.5 mL and about 5 mL. In other embodiments, asecond stop 156 can be supplied such thatprawl 104 can only travel betweensecond stop 156 and stop 154. This distance ofprawl 104 travel can be equivalent to an extruded amount fromsyringe 122. - For example, in some embodiments,
predetermined distance 152 can define a dosage of substance becausepredetermined distance 152 can cause axial movement of plunger head 128 a secondpre-determined distance 160. This secondpre-determined distance 160 in turn represents a particular volume of substance extruded fromsyringe 122. - In other embodiments, the use of
accessory 100 may not deliver a predetermined amount of substance or material but rather the amount delivered may still require use of visual marks onsyringe 122. - In any circumstance, whether pre-determined or manual delivery amounts, once full extension of
accessory 100 is achieved,claws 118 can be disengaged fromplunger 126 by pullinghandle 102 upward and away fromsyringe 122 as illustrated inFIG. 6 . This disengagement can “re-set” the accessory to reengage theplunger 126 and deliver a subsequent dose of substance or material. - In some embodiments, when
spring 144 is used, theupward force 158 needed to disengageclaws 118 fromplunger 126 can be reduced. Also, usingspring 144 can pull prawl 104 towardhandle 102 thereby “re-setting”accessory 100 for subsequent delivery. - Kits including an accessory as described herein are also contemplated. A kit can include an accessory that is configured to be attached to a syringe and instructions for use. In other embodiments, a kit can include an accessory, a syringe and instructions for use. In still other embodiments, a kit can include an accessory, a syringe filled with an injectable substance or a separate vial including the substance, and instructions for use. In other embodiments, a kit can include a syringe including an integrated accessory. In other embodiments, a kit can include a syringe including an integrated accessory and an injectable substance within the syringe or in a vial in the kit.
- Unless otherwise indicated, all numbers expressing quantities of ingredients, properties such as molecular weight, reaction conditions, and so forth used in the specification and claims are to be understood as being modified in all instances by the term “about.” Accordingly, unless indicated to the contrary, the numerical parameters set forth in the specification and attached claims are approximations that may vary depending upon the desired properties sought to be obtained by the present invention. At the very least, and not as an attempt to limit the application of the doctrine of equivalents to the scope of the claims, each numerical parameter should at least be construed in light of the number of reported significant digits and by applying ordinary rounding techniques. Notwithstanding that the numerical ranges and parameters setting forth the broad scope of the invention are approximations, the numerical values set forth in the specific examples are reported as precisely as possible. Any numerical value, however, inherently contains certain errors necessarily resulting from the standard deviation found in their respective testing measurements.
- The terms “a,” “an,” “the” and similar referents used in the context of describing the invention (especially in the context of the following claims) are to be construed to cover both the singular and the plural, unless otherwise indicated herein or clearly contradicted by context. Recitation of ranges of values herein is merely intended to serve as a shorthand method of referring individually to each separate value falling within the range. Unless otherwise indicated herein, each individual value is incorporated into the specification as if it were individually recited herein. All methods described herein can be performed in any suitable order unless otherwise indicated herein or otherwise clearly contradicted by context. The use of any and all examples, or exemplary language (e.g., “such as”) provided herein is intended merely to better illuminate the invention and does not pose a limitation on the scope of the invention otherwise claimed. No language in the specification should be construed as indicating any non-claimed element essential to the practice of the invention.
- Groupings of alternative elements or embodiments of the invention disclosed herein are not to be construed as limitations. Each group member may be referred to and claimed individually or in any combination with other members of the group or other elements found herein. It is anticipated that one or more members of a group may be included in, or deleted from, a group for reasons of convenience and/or patentability. When any such inclusion or deletion occurs, the specification is deemed to contain the group as modified thus fulfilling the written description of all Markush groups used in the appended claims.
- Certain embodiments of this invention are described herein, including the best mode known to the inventors for carrying out the invention. Of course, variations on these described embodiments will become apparent to those of ordinary skill in the art upon reading the foregoing description. The inventor expects skilled artisans to employ such variations as appropriate, and the inventors intend for the invention to be practiced otherwise than specifically described herein. Accordingly, this invention includes all modifications and equivalents of the subject matter recited in the claims appended hereto as permitted by applicable law. Moreover, any combination of the above-described elements in all possible variations thereof is encompassed by the invention unless otherwise indicated herein or otherwise clearly contradicted by context.
- Furthermore, numerous references have been made to patents and printed publications throughout this specification. Each of the above-cited references and printed publications are individually incorporated herein by reference in their entirety.
- Specific embodiments disclosed herein may be further limited in the claims using consisting of or and consisting essentially of language. When used in the claims, whether as filed or added per amendment, the transition term “consisting of” excludes any element, step, or ingredient not specified in the claims. The transition term “consisting essentially of” limits the scope of a claim to the specified materials or steps and those that do not materially affect the basic and novel characteristic(s). Embodiments of the invention so claimed are inherently or expressly described and enabled herein.
- In closing, it is to be understood that the embodiments of the invention disclosed herein are illustrative of the principles of the present invention. Other modifications that may be employed are within the scope of the invention. Thus, by way of example, but not of limitation, alternative configurations of the present invention may be utilized in accordance with the teachings herein. Accordingly, the present invention is not limited to that precisely as shown and described.
Claims (22)
1. A syringe extrusion accessory comprising:
a handle operatively coupled to an attachment portion configured to attach to a syringe; and
at least one prawl operatively coupled to the handle and configured to engage with a plunger of the syringe,
wherein the syringe extrusion accessory is configured to transfer a substantially perpendicular force applied to the handle to an axial force to push the plunger and extrude a product from the syringe.
2. The syringe extrusion accessory of claim 1 , wherein the at least one prawl includes at least one claw.
3. The syringe extrusion accessory of claim 1 , wherein the prawl has a sinusoidal shape.
4. The syringe extrusion accessory of claim 1 , wherein the handle is coupled to the attachment portion through a hinge.
5. The syringe extrusion accessory of claim 1 , wherein the prawl is coupled to the handle through a hinge.
6. The syringe extrusion accessory of claim 5 , wherein the prawl is further attached to the handle with a spring.
7. The syringe extrusion accessory of claim 6 , wherein the spring is a compression spring.
8. The syringe extrusion accessory of claim 1 , wherein the substantially perpendicular force is between about 1 degree and about 20 degrees perpendicular to the syringe.
9. The syringe extrusion accessory of claim 1 , wherein the attachment portion is configured to attach to a flange portion of the syringe.
10. The syringe extrusion accessory of claim 1 , wherein the handle includes a depression configured to apply force from at least one finger.
11. A method of extruding a product from a syringe, the method comprising:
applying a substantially perpendicular force to an accessory associated with the syringe; and
extruding the product from the syringe,
wherein the accessory includes a handle operatively coupled to an attachment portion configured to attach to a syringe; and at least one prawl operatively coupled to the handle and configured to engage with a plunger of the syringe.
12. The method of claim 11 , wherein the accessory is configured to transfer a substantially perpendicular force applied to the handle to an axial force to push the plunger and extrude the product from the syringe.
13. The method of claim 11 , wherein the substantially perpendicular force is applied to a depression on the handle.
14. The method of claim 11 , wherein the method further comprises attaching the accessory to the syringe.
15. The method of claim 14 , wherein the accessory is configured to attach to a flange on the syringe.
16. The method of claim 11 , wherein the substantially perpendicular force is between about 1 degree and about 20 degrees perpendicular to the syringe.
17. The method of claim 11 , wherein the at least one prawl includes at least one claw.
18. The method of claim 11 , wherein the prawl has a sinusoidal shape.
19. The method of claim 11 , wherein the handle is coupled to the attachment portion through a hinge.
20. The method of claim 11 , wherein the prawl is coupled to the handle through a hinge.
21. The method of claim 20 , wherein the prawl is further attached to the handle with a spring.
22. The method of claim 21 , wherein the spring is a compression spring.
Priority Applications (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US14/284,285 US20140350518A1 (en) | 2013-05-23 | 2014-05-21 | Syringe extrusion accessory |
PCT/US2014/039266 WO2014190224A1 (en) | 2013-05-23 | 2014-05-23 | Syringe extrusion accessory |
CA2913333A CA2913333C (en) | 2013-05-23 | 2014-05-23 | Syringe extrusion accessory |
EP14733435.3A EP2999506A1 (en) | 2013-05-23 | 2014-05-23 | Syringe extrusion accessory |
AU2014268410A AU2014268410A1 (en) | 2013-05-23 | 2014-05-23 | Syringe extrusion accessory |
US15/011,897 US10357615B2 (en) | 2013-05-23 | 2016-02-01 | Syringe extrusion accessory |
US16/510,808 US11684719B2 (en) | 2013-05-23 | 2019-07-12 | Methods of treatment using a syringe extrusion accessory |
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Also Published As
Publication number | Publication date |
---|---|
US20160144125A1 (en) | 2016-05-26 |
US11684719B2 (en) | 2023-06-27 |
US10357615B2 (en) | 2019-07-23 |
US20190351146A1 (en) | 2019-11-21 |
CA2913333C (en) | 2021-06-15 |
EP2999506A1 (en) | 2016-03-30 |
AU2014268410A1 (en) | 2015-12-17 |
WO2014190224A1 (en) | 2014-11-27 |
CA2913333A1 (en) | 2014-11-27 |
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Legal Events
Date | Code | Title | Description |
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STCB | Information on status: application discontinuation |
Free format text: ABANDONED -- FAILURE TO RESPOND TO AN OFFICE ACTION |