US20100280388A1 - CMUT Packaging for Ultrasound System - Google Patents

CMUT Packaging for Ultrasound System Download PDF

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US20100280388A1
US20100280388A1 US12/745,754 US74575408A US2010280388A1 US 20100280388 A1 US20100280388 A1 US 20100280388A1 US 74575408 A US74575408 A US 74575408A US 2010280388 A1 US2010280388 A1 US 2010280388A1
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flexible
cmut
ultrasonic transducer
ultrasonic
flexible member
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US9408588B2 (en
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Yongli Huang
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Kolo Medical (suzhou) Co Ltd
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Kolo Technologies Inc
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/12Diagnosis using ultrasonic, sonic or infrasonic waves in body cavities or body tracts, e.g. by using catheters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/44Constructional features of the ultrasonic, sonic or infrasonic diagnostic device
    • A61B8/4483Constructional features of the ultrasonic, sonic or infrasonic diagnostic device characterised by features of the ultrasound transducer
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B06GENERATING OR TRANSMITTING MECHANICAL VIBRATIONS IN GENERAL
    • B06BMETHODS OR APPARATUS FOR GENERATING OR TRANSMITTING MECHANICAL VIBRATIONS OF INFRASONIC, SONIC, OR ULTRASONIC FREQUENCY, e.g. FOR PERFORMING MECHANICAL WORK IN GENERAL
    • B06B1/00Methods or apparatus for generating mechanical vibrations of infrasonic, sonic, or ultrasonic frequency
    • B06B1/02Methods or apparatus for generating mechanical vibrations of infrasonic, sonic, or ultrasonic frequency making use of electrical energy
    • B06B1/0292Electrostatic transducers, e.g. electret-type
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/44Constructional features of the ultrasonic, sonic or infrasonic diagnostic device
    • A61B8/4444Constructional features of the ultrasonic, sonic or infrasonic diagnostic device related to the probe
    • A61B8/445Details of catheter construction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/44Constructional features of the ultrasonic, sonic or infrasonic diagnostic device
    • A61B8/4483Constructional features of the ultrasonic, sonic or infrasonic diagnostic device characterised by features of the ultrasound transducer
    • A61B8/4488Constructional features of the ultrasonic, sonic or infrasonic diagnostic device characterised by features of the ultrasound transducer the transducer being a phased array
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B06GENERATING OR TRANSMITTING MECHANICAL VIBRATIONS IN GENERAL
    • B06BMETHODS OR APPARATUS FOR GENERATING OR TRANSMITTING MECHANICAL VIBRATIONS OF INFRASONIC, SONIC, OR ULTRASONIC FREQUENCY, e.g. FOR PERFORMING MECHANICAL WORK IN GENERAL
    • B06B1/00Methods or apparatus for generating mechanical vibrations of infrasonic, sonic, or ultrasonic frequency
    • B06B1/02Methods or apparatus for generating mechanical vibrations of infrasonic, sonic, or ultrasonic frequency making use of electrical energy
    • B06B1/06Methods or apparatus for generating mechanical vibrations of infrasonic, sonic, or ultrasonic frequency making use of electrical energy operating with piezoelectric effect or with electrostriction
    • B06B1/0644Methods or apparatus for generating mechanical vibrations of infrasonic, sonic, or ultrasonic frequency making use of electrical energy operating with piezoelectric effect or with electrostriction using a single piezoelectric element
    • B06B1/0651Methods or apparatus for generating mechanical vibrations of infrasonic, sonic, or ultrasonic frequency making use of electrical energy operating with piezoelectric effect or with electrostriction using a single piezoelectric element of circular shape
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B06GENERATING OR TRANSMITTING MECHANICAL VIBRATIONS IN GENERAL
    • B06BMETHODS OR APPARATUS FOR GENERATING OR TRANSMITTING MECHANICAL VIBRATIONS OF INFRASONIC, SONIC, OR ULTRASONIC FREQUENCY, e.g. FOR PERFORMING MECHANICAL WORK IN GENERAL
    • B06B3/00Methods or apparatus specially adapted for transmitting mechanical vibrations of infrasonic, sonic, or ultrasonic frequency
    • HELECTRICITY
    • H04ELECTRIC COMMUNICATION TECHNIQUE
    • H04RLOUDSPEAKERS, MICROPHONES, GRAMOPHONE PICK-UPS OR LIKE ACOUSTIC ELECTROMECHANICAL TRANSDUCERS; DEAF-AID SETS; PUBLIC ADDRESS SYSTEMS
    • H04R31/00Apparatus or processes specially adapted for the manufacture of transducers or diaphragms therefor
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T29/00Metal working
    • Y10T29/49Method of mechanical manufacture
    • Y10T29/49002Electrical device making
    • Y10T29/49005Acoustic transducer

Abstract

Ultrasonic scanners and methods of manufacturing ultra-sonic scanners. One embodiment of a method includes integrating a flexible electronic device (e.g. an IC) and a flexible ultrasonic transducer (e.g. a portion of a circular CMUT array) with a flexible member. The IC, the transducer, and the flexible member can form a flexible subassembly which is rolled up to form an ultrasonic scanner. The integration of the IC and the transducer can occur at the same time. In the alternative, the integration of the electronic device can occur before the integration of the transducer. Moreover, the integration of the transducer can include using a semiconductor technique. Furthermore, the rolled up subassembly can form a lumen or can be attached to a lumen. The method can include folding a portion of the flexible subassembly to form a forward looking transducer. The flexible member of some subassemblies can include a pair of arms.

Description

    PRIORITY
  • This application claims priority from U.S. Provisional Application Ser. No. 60/992,020, filed Dec. 3, 2007 and U.S. Provisional Application Ser. No. 61/024,843, filed Jan. 30, 2008.
  • BACKGROUND
  • The present application relates to capacitive micromachined ultrasonic transducers (CMUT) and, more particularly to the packaging of CMUT based ultrasonic transducers, devices, and systems
  • A catheter allows surgical personnel to diagnose and treat conditions deep within a patient's body by navigating the distal end of the catheter to the site where some condition might exist. Then, surgical personnel can operate various sensors, instruments, etc. at the site to perform certain procedures with minimal intrusive effect on the patient. One type of device that has found widespread use is the ultrasonic scanner. Ultrasonic scanners generate acoustic waves at frequencies selected for their ability to allow the acoustic waves to penetrate various tissues and other biological structures and return echoes there from. Often, it is desired to select frequencies on the order of 20 MHz or higher. Images of the tissue surrounding the ultrasonic scanner can be derived from these returned echoes. Another type of ultrasonic device is used to perform High-Intensity Focused Ultrasound (HIFU) through an ultrasonic transducer equipped catheter; it can safely and effectively ablate atrial fibrillation (AF) from the outside surface of a beating heart. Two types of ultrasonic transducers exist, those which are based on piezoelectric crystals (i.e., a crystal fabricated from a piezoelectric material or a piezoelectric composite material) and those based on capacitive micromachined ultrasonic transducers (CMUTs and embedded spring CMUTS or ESCMUTs).
  • CMUTs typically include two spaced apart electrodes with a membrane attached to one of the two electrodes. In operation, an alternating current (AC) signal is used to charge the electrodes to differing voltages. The differential voltage induces movement of the electrode attached to the membrane and hence, the membrane itself. A piezoelectric transducer (PZTs) also applies an AC signal to the crystal therein causing it to vibrate and produce acoustic waves. The echoes returned to the crystal are used to derive images of the surrounding tissue.
  • Thus, surgical personnel have found it useful to employ ultrasonic scanner equipped catheters to obtain images of certain tissues (e.g. blood vessels), structures, etc. within human (and animal) patients and to view the effects of therapy thereon. For instance, ultrasonic transducers can provide images which allow medical personnel to determine whether blood is flowing through a particular blood vessel.
  • Some catheters include a single ultrasonic transducer situated at, or near, the distal end of the catheter whereas other catheters include arrays of ultrasonic transducers at the distal end of the catheter. These ultrasonic transducer transducers can be arrange along the side of the catheter and can point outward there from. If so they can be referred to as “side looking” transducers. When the catheter only has one side looking transducer the catheter can be rotated to obtain images of the tissue in all directions around the catheter. Otherwise, the catheter can have ultrasonic transducers pointed in all directions around the catheter.
  • In other situations, catheters can have ultrasonic transducers arranged at the distal end of the catheter which point in a distal direction from the end of the catheter. These types of ultrasonic transducers can be referred to as “forward looking” transducers. Forward looking transducers can be useful for obtaining images of tissue in front of (i.e. “forward” of) the catheter.
  • Since in both ultrasound imaging and ultrasound therapy, the ultrasound system focuses ultrasound in a target zone to achieve either imaging or therapy, a catheter based ultrasound system used for imaging can also be configured to perform therapy by selecting a proper ultrasound frequency and energy input.
  • SUMMARY
  • Embodiments provide ultrasonic transducers, device, and systems, (e.g. scanners or HIFU devices) and methods of manufacturing ultrasonic systems. More particularly, a method practiced according to one embodiment includes integrating a flexible electronic device (e.g. an integrated circuit) with a flexible member and integrating a flexible ultrasonic transducer (e.g. a portion of a circular CMUT array) with the flexible member. The integrated flexible electronic device, flexible ultrasonic transducer, and flexible member can form a flexible subassembly which is rolled up to form the ultrasonic transducer. The packaging methods disclosed herein can be used to make miniaturized ultrasonic transducers, devices, and systems. These methods can also be used to make flexible ultrasonic transducers, devices, and systems. Moreover, the resulting ultrasonic transducers, devices, and systems can be mechanically flexible. In some embodiments, these ultrasonic transducers, devices, and systems can also be operationally flexible in that they can be applied to a variety of situations including: IVUS/ICE) imaging and various forms of therapy. For example, these ultrasonic transducers, devices, and systems can be used for, but not limited to, high intensity focused ultrasound (HIFU) ablation for AF on a human patient's heart.
  • In some embodiments, the integration of the flexible electronic device and the flexible ultrasonic transducer with the flexible member occurs at the same time. Furthermore, the integration of the ultrasonic transducer can be performed from the side of ultrasonic transducer which includes its active surface. In the alternative, the integration of the flexible electronic device can occur before (or after) the integration of the flexible ultrasonic transducer. Moreover, the integration of the flexible ultrasonic transducer can include using a semiconductor technique. In some embodiments, the rolled up flexible subassembly forms a lumen which can be coupled to the lumen of a catheter. However, the rolled up flexible subassembly can be attached to a lumen of a catheter instead. In some embodiments, the method includes folding a portion of the flexible member (which hosts the flexible ultrasonic transducer) through an angle of about ninety degrees to form a forward looking ultrasonic transducer. The flexible member of some embodiments can include a pair of arms attached to portions of a circular array of CMUT transducers. As the arms (and the rest of the flexible member) are rolled up, the circular CMUT array can be folded through about ninety degrees to form a ring shaped CMUT array. The ring shaped CMUT array can then be used as a forward looking CMUT array.
  • One embodiment of an ultrasonic system disclosed herein includes a flexible electronic device (e.g. an integrated circuit), a flexible ultrasonic transducer; and a flexible member with the flexible electronic device and the flexible ultrasonic transducer integrated with the flexible member. The integrated flexible electronic device, the flexible ultrasonic transducer, and the flexible member can form a flexible subassembly which is rolled up to form the ultrasonic scanner. In some embodiments, the rolled up flexible subassembly is a lumen or, instead, can be attached to a lumen of a catheter. The flexible ultrasonic transducer can include a through wafer interconnect and a portion of a circular CMUT array in communication therewith. Moreover, the ultrasonic transducer can be a forward looking, ring shaped CMUT array.
  • Accordingly, embodiments provide many advantages over previously available ultrasonic transducers and, more particularly, over PZT based ultrasonic systems. For instance, embodiments provide ultrasonic scanners which can operate at higher frequencies and with wider bandwidths than heretofore possible. Embodiments also provide ultrasonic systems with smaller form factors than those of previously available ultrasonic transducers. In addition, embodiments provide methods of manufacturing ultrasonic scanners which are simpler, less costly, and faster than previously available ultrasonic manufacturing methods.
  • BRIEF DESCRIPTION OF THE FIGURES
  • FIG. 1 illustrates a perspective view of a CMUT based ultrasonic scanner and of a flexible subassembly for a CMUT based ultrasonic scanner of one embodiment.
  • FIG. 2 illustrates a perspective view of another CMUT based ultrasonic scanner and of a flexible subassembly for a CMUT based ultrasonic scanner of one embodiment.
  • FIG. 3 illustrates perspective views of a flexible subassembly for a CMUT based ultrasonic scanner of one embodiment.
  • FIG. 4 illustrates a method of integrating ICs and CMUT arrays with flexible members for a CMUT based ultrasonic scanner of one embodiment.
  • FIG. 5 illustrates another method of integrating ICs and CMUT arrays with flexible members for a CMUT based ultrasonic system of one embodiment.
  • FIG. 6 illustrates another method of integrating ICs and CMUT arrays with flexible members for a CMUT based ultrasonic system of one embodiment.
  • FIG. 7 illustrates another method of integrating ICs and CMUT arrays with flexible members for a CMUT based ultrasonic scanner of one embodiment.
  • FIG. 8 illustrates yet another method of integrating ICs and CMUT arrays with flexible members for a CMUT based ultrasonic scanner of one embodiment.
  • FIG. 9 illustrates perspective views of a flexible subassembly for a CMUT based ultrasonic scanner of one embodiment.
  • FIG. 10 illustrates a method of manufacturing a flexible IC subassembly for a CMUT based ultrasonic scanner of one embodiment.
  • FIG. 11 illustrates another method of manufacturing CMUT arrays and CMUT elements for a CMUT based ultrasonic scanner of one embodiment.
  • FIG. 12 illustrates methods of various embodiments of manufacturing CMUT arrays.
  • DETAILED DESCRIPTION
  • One component of a capacitive micromachined ultrasonic transducer (CMUT) based system (e.g. IVUS/ICE scanner, miniature high intensity focus ultrasound (HIFU) device, etc.) of various embodiments is a flexible member with a CMUT array(s) and/or an IC(s) integrated thereon. The integration of the CMUT arrays and ICs can be performed at the same time using semiconductor and MEMS fabrication and packaging techniques (hereinafter “semiconductor” techniques) or can be performed at different times. Semiconductor techniques can be used in batch processes thereby providing relatively simple, reliable, and cost efficient methods of manufacturing CMUT based ultrasonic systems. The integrated flexible members (with the CMUT arrays and/or ICs) can be folded, or otherwise arranged, to fit within limited spaces and can be made to conform to various surfaces (even those with compound curvature). More specifically, the ultrasonic systems disclosed herein can be included on, or in, various types of catheters. More particularly, these batch semiconductor processes can provide methods of manufacturing ultrasonic systems which are simpler, more reliable, and more cost efficient than methods of manufacturing piezoelectric transducer (PZT) based ultrasonic systems.
  • Though piezoelectric transducers (PZTs) can perform some desirable diagnostic and therapeutic functions, it remains difficult to obtain piezoelectric transducers (PZTs) with small form factors. More specifically, due to constraints associated with the materials from which PZTs are manufactured, it remains difficult to design and manufacture catheters with PZTs small enough to fit within many catheters designed to be navigated through various cardiovascular vessels, neurovascular vessels, and other biologic structures. Moreover, PZT materials do not lend themselves well to relatively high frequency regimes. For example, it is difficult to design and manufacture a PZT capable of operation in the region near (and above) 20 MHz which is useful for imaging biological tissues.
  • Furthermore, to form cylindrical arrays of PZT (such as the cylindrical arrays desirable for inclusion on various catheters) the individual PZTs must be diced from flat sheets of the transducers. The individual PZTs can then be arranged in a cylindrical array on the catheter. As a result, some of the individual PZTs (or groups thereof) can be damaged or contaminated with kerf or other contaminants during the dicing and assembly operations. Additionally, the dicing operation and the assembly of the individual PZTs on to the catheter can lead to variations in the operational characteristics of the individual PZTs. Thus, previously available PZTs have found use in only certain ultrasound applications. This disclosure provides CMUT based ultrasonic systems, and catheters equipped with such CMUTs which address at least some of the shortcomings of PZTs. As discussed herein, the CMUT based ultrasonic systems and catheters disclosed herein also possess other advantages.
  • CMUTs transmit and detect acoustic waves in adjacent media using two plate-like structures arranged to form a capacitor. The plates (or electrodes coupled to the plates) can be repetitively charged to displace one plate relative to the other thereby generating the acoustic waves. Typically, an alternating current (AC) charges the plates. In the alternative, the plates may be charged to a selected voltage (with, for example, a direct current or DC signal) and can be used to sense acoustic waves which impinge on the exposed plate and therefore displace that plate relative to the other plate. The displacement of the exposed plate causes a change in the capacitance of the CMUT. The resulting electric signal generated by the CMUT can be analyzed to generate images of the media surrounding the CMUT. Some CMUT based ultrasonic systems include switches so that, when the switch is in one position, the switch allows the CMUT to transmit acoustic waves and, when the switch is in the other position, the switch allows the CMUT to detect acoustic waves.
  • CMUTs can be fabricated separately or can be fabricated in various types of arrays. For instance, a one dimensional (1-D) array of CMUTs can be fabricated wherein the various CMUTs are formed in a linear array. 2-D CMUT arrays can also be fabricated in which the various CMUTs are formed in various patterns including, for example, rows and columns. The rows and columns can create arrays which are generally square, rectangular, or other shapes. Moreover, individual CMUTs can be operated separately; can be operated in conjunction with other CMUTs; or can be operated in conjunction with all of the CMUTs in a particular array or scanner. For instance, the signals driving the various CMUTs can be timed to operate a number of the CMUTs as a phased array to direct the acoustic energy in a particular direction(s).
  • CMUT arrays can be formed to be flexible so that the array can conform to a surface, cavity, etc. with a desired or given shape or curvature. For instance, CMUT arrays can be fitted to conform to the shape of a particular instrument, catheter, or other device. Similarly, the ICs (or other electronic circuits) used to drive the CMUTs (and sense the signals there from) can be formed to be flexible also. Furthermore, the CMUTs and ICs can be integrated with each other and the instrument at the same time using the same techniques or at separate times using the same (or different) techniques as disclosed herein.
  • More particularly, the CMUTs and ICs of some embodiments can be integrated with each other on a flexible member at the same time using semiconductor or micro electromechanical systems (MEMS) fabrication and packaging techniques (hereinafter “semiconductor” techniques). The flexible member, with the CMUTs and/or ICs on it, can be wrapped onto a catheter (or other device) to form a catheter with a CMUT based ultrasonic system. These CMUT based ultrasonic systems serving as ultrasound scanners can be forward looking, side looking, or combinations thereof. They can also be used to perform imaging, therapeutic functions (e.g. tissue ablation), or combinations thereof. In some embodiments, other transducers (e.g., pressure, temperature, etc.) can be fabricated and integrated with the CMUTs and ICs on the flexible membrane.
  • FIG. 1A illustrates a perspective view of a flexible subassembly for a capacitive micromachined transducer (CMUT) based ultrasonic system of one embodiment. The flexible subassembly 108 includes a CMUT array 110, support electronics 120 for the CMUT array 110, and a flexible member 130. In some embodiments, the support electronics 120 are in the form of one or more integrated circuits (ICs). The flexible member 130 mechanically couples the CMUT array 110 and the support electronics 120 while allowing the CMUT array 110 and the support electronics 120 to move relative to each other during assembly. Flexible member 130 can also provide electrical connectivity between the CMUT array 110 and support electronics 120. Moreover, each of the CMUT elements with in the CMUT array 110 are flexibly coupled to each other. Likewise, various portions of the support electronics 120 can be flexibly coupled to each other.
  • FIG. 1B illustrates a perspective view of a CMUT based ultrasonic system (e.g. scanner) of one embodiment. More particularly, the CMUT based ultrasonic system 109 can be formed from the flexible subassembly 108. In one embodiment, flexible subassembly 108 is rolled into a cylindrical shape as indicated by reference arrow 136 to form CMUT based ultrasonic system 109. As illustrated in FIG. 1B, CMUT based ultrasonic system 109 can be a side looking ultrasonic scanner. CMUT based ultrasonic scanner 109 can be attached to a lumen of a catheter, or other device, and can be used to image tissues within a patient's body. CMUT based ultrasonic scanner 109 can also focus the ultrasound into the region generally adjacent to the scanner to do HIFU ablation. While the flexible subassembly 108 can be wrapped around objects, rolled into a tube, partial lumen, or lumen, or formed into other shapes (even those with compound curves).
  • FIG. 2 illustrates a perspective view of another flexible subassembly for a CMUT based ultrasonic system of one embodiment. The flexible subassembly 208 includes a circular CMUT array 210, supporting ICs 220, and a flexible member 230. The flexible member 230 includes a pair of arcuate arms 232 which project from the ICs 220 and to the circular CMUT array 210. The arms 232 can also define a void 234 which will allow arms 232 to conform to the overall cylindrical shape of the CMUT based ultrasonic system 209 illustrated in FIG. 2B. To form the ultrasonic system 209 from the flexible subassembly 208, the circular CMUT array 210 can be folded inward as the flexible subassembly 208 is rolled into a cylindrical shape. Thus, the individual elements of the circular CMUT array 210 can point distally from the CMUT based ultrasonic system 209. Accordingly, the CMUT based ultrasonic system 209 can be a forward looking, CMUT based, ultrasonic scanner. CMUT based ultrasonic scanner 209 can also focus the ultrasound into the region forward of the scanner to do HIFU ablation.
  • With reference now to FIG. 3A, a perspective view of a flexible subassembly for a CMUT based ultrasonic system of one embodiment is illustrated. The flexible subassembly 308 includes a CMUT array 310 and ICs 320 lying parallel to, and spaced apart from, each other on a flexible member 330. The CMUT array 310 can be a single element CMUT or a CMUT array (e.g. 1 dimensional, 2 dimensional, 1.5 dimensional, or any other types of CMUT arrays). Thus, portions 350 of the flexible member 330 span the distance between at least some of the ICs 320 and the CMUT array 310. The flexible assembly 308 can be folded at these portions 350 of the flexible member 330 to form a compact ultrasonic system 309 (see FIG. 3B). The compact ultrasonic system 309 can resemble a stack of ICs 320 with the CMUT array 310 at one end of the stack and the portions 350 of the flexible member defining layers of the flexible member between the CMUT array 310 and the ICs 320. Compact ultrasonic system 309 can be made small enough so that it can fit within a catheter and within other similarly limited spaces. While the flexible assembly 308 can be folded into a stack, it can also be wrapped around objects, rolled into a tube or lumen, or formed into other shapes (even those with compound curves).
  • With reference now to FIGS. 4-8, various methods of integrating ICs and CMUT arrays with flexible members are illustrated. These methods can use various semiconductor techniques to perform the integration of the ICs and the CMUT arrays with the flexible members. Indeed, in some embodiments, the same semiconductor techniques are used to integrate the ICs and to integrate the CMUT arrays with the flexible member. In contrast, PZT based ultrasonic scanners require different techniques to integrate the PCT transducers and ICs (or other supporting electronics) of PZT based ultrasonic systems.
  • FIG. 4 illustrates a method of integrating ICs and CMUT arrays with flexible members to form a flexible subassembly 408 for CMUT based ultrasonic systems of one embodiment. More particularly, the flexible member 430 can be fabricated on the wafer 400 (or some other substrate) using various semiconductor techniques. FIG. 4 further illustrates that a wafer 400 can be used to integrated CMUT arrays 410 and ICs 420 with a flexible member 430. During the integration of the CMUT arrays 410 and the ICs 420, various structures such as a flexible member 430, comprising at least one insulation layer 431-435, at least one conductive layer 432-434, and bonding pads 439, can be formed. In the method illustrated by FIG. 4, the CMUT arrays 410 and the ICs 420 can be fabricated separately.
  • Due, in part, to the semiconductor techniques used to fabricate the flexible member 430, the dimensions of various interconnects to be formed in the flexible member 430 can be controlled to a greater degree than the corresponding dimensions of interconnects in the printed circuit boards (PCBs) used in PZT based ultrasonic systems. Additionally, the method illustrated by FIG. 4 allows interconnect density to be increased (as compared to PZT based ultrasonic transducer interconnect density) by fabricating multiple conductive layers 432-434 with better dimension control. Thus, miniature ultrasonic systems can be manufactured in accordance with various embodiments.
  • With reference now to FIG. 4.1, the insulation layer 431 can be coated and patterned on to the wafer 400 to form a first layer of the flexible member 430. Note that the wafer 400 can be a silicon wafer, a glass wafer, or some other substrate and that the insulation layer 431 can be coated or formed, e.g. oxide, nitride, Parylene, polyimide, polymer, PDMS, Kapton, etc.
  • One of the conductive layers 432 can be formed and patterned on to the wafer 400 (as illustrated by FIG. 4.2) to form various interconnects within the flexible member 430. As noted previously, additional insulation layers 433-435 and additional conductive layers 432-434 can be coated and patterned on to the wafer 400 as desired to form additional interconnects within the flexible member 430 (see FIG. 4.3). The material of the conductive layers 432-434 can be Al, Au, Cr, Ti, Cu, etc.
  • FIG. 4.4 illustrates that bonding pads 439 can be fabricated and patterned from a conductive material on various interconnects previously to mate with corresponding contacts on the CMUT arrays 410, the ICs 420, and other components. The material from which the bonding pads 439 can be formed and can be selected based on the techniques which, in the process illustrated in FIGS. 4.4 and 4.5, are selected to integrate the CMUT arrays 410 and ICs 420 with the flexible member 430. Thus, as illustrated by FIG. 4.5 the CMUT arrays 410 and the ICs 420 can be positioned on the bonding pads 439 and bonded therewith. More specifically, the bonding, either in device level or wafer level, of the CMUT arrays 410 and the ICs 420 with the bonding pads 439 can be performed with eutectic bonding, thermal compression bonding, as well as various flip-chip bonding methods. The flexible subassembly 408, including the flexible member, 430, the CMUT arrays 410 and the ICs 420, can then be separated from the wafer 400 as illustrated by FIG. 4.6. The flexible member comprises the layers 431-435 and bond pads 439. In some embodiments, the integrated flexible subassembly can then subsequently be assembled into an ultrasonic system. Thus, the CMUT arrays 410 can be integrated with the flexible member 430 using the same techniques as are used to integrate the ICs 420 with the flexible member 430 (and, more particularly, semiconductor batch-process techniques).
  • FIG. 5 illustrates another method of integrating ICs and CMUT arrays with flexible members for a CMUT based ultrasonic system of one embodiment. More particularly, in stead of forming a flexible member on a prime wafer as shown in FIG. 4, the flexible member 530 in FIG. 5 is formed on a SOI wafer with fabricated CMUT arrays 510.
  • With reference now to FIG. 5.1, CMUT arrays 510 are fabricated on a SOI wafer 500. The SOI wafer comprises a device layer 501, an insulation layer 502 and a handling layer 503. In FIG. 5.2, a first pattern (e.g., trenches or openings) 570, 571 is formed from a top side of the CMUT fabrication substrate. The first pattern includes trenches (or openings) 571 which may define a boundary of each CMUT array 510 on the wafer and trenches (or openings) 570 which may define a boundary of each CMUT element in a CMUT array 510. The trench's deepest end can reach the insulation layer 502. The first pattern (e.g., trenches or openings) 570, 571 may be done during or after CMUT fabrication. After this step, the subsequent processing can be similar to the method of FIG. 4 from FIG. 4.1 to FIG. 4.4 to form the flexible member 530 on the CMUT array (FIG. 5.3). As illustrated by FIG. 5.4, the ICs 520 can be positioned on the bonding pads 539 and bonded therewith. More specifically, the bonding, either in device level or wafer level, of the ICs 520 with the bonding pads 539 can be performed with eutectic bonding, thermal compression bonding, as well as various flip-chip bonding methods. The handling layer 503 of the SOI wafer 500 may be removed. And then the flexible subassembly 508, including the flexible member 530, the CMUT arrays 510 and the ICs 520, can then be separated from the wafer 500 as illustrated by FIG. 5.5. Furthermore, as illustrated by FIG. 5.5, the method illustrated by FIG. 5 can result in the CMUT arrays 510 being positioned on one side of the flexible member 530 (e.g., the side which was fabricated onto the wafer 500) and the ICs 520 being positioned on the other side of the flexible member 530.
  • FIG. 6 illustrates another method of integrating ICs and CMUT arrays with flexible members for a CMUT based ultrasonic system of one embodiment. More particularly, in stead of forming a flexible member on a prime wafer as shown in FIG. 4, the flexible member 630 in FIG. 6 is formed on a SOI wafer with ICs 610 fabricated thereon.
  • With reference now to FIG. 6.1, supporting ICs 620 can be fabricated on a SOI wafer 600. The SOI wafer comprises a device layer 601, an insulation layer 602 and a handling layer 603. In FIG. 6.2, a first pattern (e.g., trenches or openings) 671 can be formed from one side (e.g. the top side) of the IC fabrication substrate. The first pattern includes trenches (or openings) 671 which may define a boundary of each IC 610 on the wafer. The trench's deepest end can reach the insulation layer 602. After this step, the subsequent processing can be similar to the method of FIG. 4 from FIG. 4.1 to FIG. 4.4 to form the flexible member 630 on the ICs 620 (FIG. 6.3). As illustrated by FIG. 6.4, the CMUT arrays 610 can be positioned on the bonding pads 639 and bonded therewith. More specifically, the bonding, either in the device level or wafer level, of the CMUT arrays 610 with the bonding pads 639 can be performed with eutectic bonding, thermal compression bonding, as well as various flip-chip bonding methods. The handling layer 603 of the SOI wafer 600 may be removed. And then the flexible subassembly 608, including the flexible member 630, the CMUT arrays 610 and the ICs 620, can then be separated from the wafer 600 as illustrated by FIG. 6.5.
  • FIG. 7 illustrates another method of integrating ICs and CMUT arrays with flexible members for a CMUT based ultrasonic system of one embodiment. In the method illustrated by FIG. 7, a flexible member 730 can be formed on various CMUT arrays 710 and ICs 720 using various semiconductor techniques. The method of FIG. 7 can be used to increase the interconnect density of the resulting ultrasonic systems (as compared to PZT based ultrasonic systems and conventional PCBs) by increasing the number of conductive layers and decreasing line width and separation of conductive wires in the flexible member 730. Moreover, the method of FIG. 7 can be performed as a batch process thereby taking advantage of the economies of scale associated with batch semiconductor techniques. Thus, many CMUT arrays 710 and ICs 720 can be integrated on various flexible members 730 at the same time.
  • With reference now to FIG. 7.1, the method illustrated therein can use a wafer 700 to form the flexible member 730 and to integrate the CMUT arrays 710 and the ICs 720 therewith. More particularly, FIG. 7 illustrates that using a SOI wafer 700 can include an embedded insulation layer 702 and a handling layer 703. Furthermore, FIG. 7 illustrates that various structures such as latch structures 705, insulation layers 731 and 732, and conductive layer 732 can be fabricated on the wafer 700.
  • More particularly, FIG. 7.1 illustrates that the latch structures 705 can be formed on wafer 700. These latch structures can be designed on the wall of the cavities 721 to latch the CMUT arrays 710 and the ICs 720 in place in cavities 721 formed at locations selected for the CMUT arrays 710 and ICs 720. The CMUT arrays 710 and the ICs 720 can be latched in place in their respective cavities 721 using the latch structures 705 (FIG. 7.2). The insulation layer 731 can then be formed and patterned (to provide access to the CMUT arrays 710 and the ICs 720) on the wafer 700 using various semiconductor techniques such as spin-coating, evaporating, sputtering, depositing, etc (FIG. 7.3). Moreover, the insulation layer 731 can be formed from various insulating materials such as Parylene, PMDS, polyimide, polymer, oxide, nitride, etc.
  • With reference now to FIG. 7.4 a conductive layer 732 can be formed on the wafer 700 to provide various interconnects within the flexible member 730 and between the CMUT arrays 710, the ICs 720, and various other components. The conductive layer 732 can be formed and patterned on the wafer 700 from various conductive materials such as Al, Au, Cu, Ti, etc. Moreover, the conductive layer 732 can be fabricated using various semiconductor techniques such as evaporation, sputtering, depositing, etc. If desired, additional insulation layers 731 and conductive layers 732 can be formed on the wafer 700 to increase the interconnect density of the resulting flexible member 730.
  • FIG. 7.5 illustrates that the flexible insulation layer 733 can be formed and patterned on the wafer 700 as a protection layer of the flexible subassembly 708. The flexible insulation layer 733 can be formed from various insulating materials such as Parylene, PMDS, polyimide, polymer, oxide, nitride, etc. and can be fabricated via spin-coating, evaporation, sputtering, deposition, etc. The flexible insulation layer 733 can be fabricated with sufficient thickness and material properties to protect the flexible member 730 (and its various layers 731-732 as well as the CMUT arrays 710 and the ICs 720) from mechanical abuse and from the environment.
  • FIG. 7.6 illustrates that, the handling layer 703 and the insulation layer 702 can be removed from the surface of the wafer 700 which is opposite the side of the wafer 700 which hosts the CMUT arrays 710, the ICs 720, and the flexible member 730. Thus, the flexible subassembly 708 including the integrated flexible member 730, the CMUT arrays 710 and ICs 720, can be removed from the wafer 700. Accordingly, the integrated flexible member 730 can be used to assemble various ultrasonic systems.
  • FIG. 8 illustrates yet another method of integrating ICs and CMUT arrays with flexible members for a CMUT based ultrasonic scanner of one embodiment. More particularly, FIG. 8.1 illustrates that the CMUT arrays 810 can be fabricated on the wafer 800 first and then the ICs 820 can be latched in place by the latch structures 805 in the wafer with fabricated CMUT arrays. In contrast, FIG. 8.2 illustrates that the ICs 820 can be fabricated on the wafer 800 first and then the CMUT arrays 810 can be latched in place in the wafer with fabricated ICs. In the methods illustrated by FIGS. 8.1 and 8.2, the fabrication of the flexible member 830, and its integration with the CMUT arrays 810 and the ICs 820 can be similar to the method illustrated by FIGS. 7.2-7.6. The finished flexible subassembly can be similar to the flexible subassembly 708 in FIG. 7.6.
  • FIG. 9 illustrates a top view of a flexible assembly 900 in which multiple CMUT arrays 910 and multiple ICs 920 packaged on a flexible member 930 to form multiple CMUT based flexible subassemblies 908 of one embodiment. The flexible assembly 900 with multiple flexible subassemblies 908 can be built using the methods illustrates in FIGS. 4-8. Each flexible subassembly 908 can be used to built a CMUT based ultrasound system The CMUT based ultrasonic flexible assembly 900 illustrated by FIG. 9 can be manufactured using methods similar to the methods disclosed herein. More particularly, the figure in the zoomed window in FIG. 9 illustrate a perspective view the CMUT based ultrasonic system built from the flexible subassembly 908 can include a CMUT array 910 and ICs 920 integrated with the flexible member 930 using various batch semiconductor techniques. Moreover, various contact pads 937 in the flexible member 930 can be fabricated to provide an electronic interface with components external to the CMUT based ultrasonic systems 908. Thus, the interconnects 936 (between the CMUT arrays 910, the ICs 920, and various other components) and the contact pads 937 in the flexible member 930 can be fabricated with the dimensional accuracy provided by various semiconductor techniques at the same time.
  • In the methods described in FIGS. 4-8, at least one of CMUT arrays (e.g. 410, 710) and ICs (e.g. 420, 720) can be separated from a first substrate (e.g. their original fabrication substrate) and then can be integrated on a flexible member (e.g. 430, 730) on a second packaging substrate (e.g. 400, 700). Therefore, at least one of the CMUT arrays and ICs can be fabricated first on their original fabrication substrate and can then be separated and can be ready for the packaged methods described herein. Usually, multiple ICs can be integrated on a flexible member individually. But they can also be integrated with a flexible sub-member on their original fabrication substrate first to form a flexible IC, and then the flexible ICs can be integrated with a CMUT array on the flexible member on the packaging substrate. Usually, CMUT arrays with multiple elements can be made to be flexible before they are integrated with ICs on the flexible member on the packaging substrate. FIGS. 10-12 illustrate several methods to make flexible CMUT arrays (e.g. 410, 720) and flexible ICs (e.g. 410, 720) which can be used in the packaging methods in FIGS. 4-8 as well as other methods.
  • With reference to FIGS. 10-12, it can be desirable to form through wafer interconnects for multiple elements in the CMUT arrays and multiple chips in the electronics (and other components) of various ultrasonic systems. Moreover, it can be desirable to form the interconnections from the inactive side of the flexible CMUT arrays. Thus, it may be desired to fabricate through wafer interconnects in the CMUT arrays and ICs. Flexible
  • CMUT arrays or ICs which include through wafer interconnections, and methods of fabricating such flexible CMUTs or ICs, are described in International Patent Application No. PCT/IB2006/051566, entitled THROUGH-WAFER INTERCONNECTION, filed on May 18, 2006 by Huang; U.S. patent application Ser. No. 11/425,128, entitled FLEXIBLE MICRO-ELECTRO-MECHANICAL TRANSDUCER, filed on Jun. 19, 2006, by Huang; International Patent Application No. ______, entitled THROUGH-WAFER INTERCONNECT, filed on Dec. 3, 2008 by Huang, and International Patent Application No. ______, entitled PACKAGING AND CONNECTING ELECTROSTATIC TRANSDUCER ARRAYS, filed on Dec. 3, 2008 by Huang which are incorporated herein as if set forth in full.
  • As described in the foregoing patent applications, flexible CMUT arrays or ICs can be formed generally as follows. A pattern of separation trenches can be formed in a wafer hosting ICs, CMUT arrays, or a combination thereof. The trenches can be formed from the side of the wafer hosting the ICs or CMUT arrays. These trenches can be formed to a selected depth and can subsequently be filled with a desired material (for example, an insulator). Material can be removed from the side of the wafer opposite the side hosting the ICs or CMUT arrays until the trenches are exposed. FIGS. 10-12 illustrate various methods of forming flexible CMUTs or ICs of various embodiments.
  • Now with reference to FIG. 10, many ultrasonic scanners contain more than one IC to support the ultrasonic transducers and, perhaps, perform other functions. In accordance with one embodiment, the multiple ICs can be integrated with the flexible member of an ultrasonic scanner using semiconductor techniques. More particularly, the ICs can be fabricated as flexible ICs and then integrated with the flexible member.
  • Furthermore, FIG. 10 illustrates that a flexible IC 1020 having a flexible sub-member 1030 s (see FIG. 10.5) and multiple IC chips 1020 a-1020 c can be fabricated from a SOI wafer 1000 on which various structures are fabricated such as: a device layer 1001, an insulation layer 1002, a handling layer 1003, one or more ICs 1020, an insulation layer 1031, a conductive layer 1032, and various trenches 1070. As illustrated by FIG. 10.1, multiple ICs 1020 a-1020 c can be fabricated on the SOI wafer 1000 with a thickness which can be defined by the device layer 1001. FIG. 10.2 illustrates that a pattern of trenches 1070 can be etched through the device layer 1001 to reach the insulation layer 1002. In a subsequent step, the back side of the wafer 1000 including the insulation layer 1002 and the handling layer 1003 can be removed to reach the trenches 1070 thereby creating the flexible IC 1020. The insulation layer 1231 can be coated on to the wafer 1000 with a pattern selected to leave various contacts on the ICs 1020 a-1220 c exposed (as illustrated by FIG. 10.3). The insulation layer 1031 may be made of a flexible material such as Parylene, polymer, polyimide, polydimethylsiloxane (PDMS), oxide, nitride, etc. The flexible sub-member 1030 s comprises one insulation layer 1031 and one conductive layer 1032 in FIG. 10.5. However, the flexible sub-member 1030 s may comprise multiple insulation layers 1031 and multiple conductive layers 1032 to increase its connection density by repeating the process steps from FIG. 10.3 and FIG. 10.4.
  • FIG. 10.4 illustrates that the conductive layer 1032 can be coated on to the wafer 1000 in a pattern selected to provide interconnects to the ICs 1020. If desired to (for example) increase the density of the interconnects, additional insulation layers 1031 and conductive layers 1032 can be coated on to the wafer 1000. The handling layer 1003 and insulation layer 1002 can be removed, as illustrated by FIG. 10.5, to expose the trenches 1070. Note that with the trenches 1070 exposed, the only materials connecting the ICs to each other can be the flexible sub-member 1030 s having the insulation layer 1031 and the conductive layer 1032. Thus, by selecting the dimensions and materials of these layers 1031 and 1032, the flexible sub-member 1030 s can be fabricated to allow the various IC chips 1020 to move relative to one another during assembly yet still remain interconnected. Thus, the flexible sub-member 1030 s can be made to be flexible with the layers 1031 and 1032 forming the flexible IC 1020. Subsequently, various CMUTs, CMUT arrays and other devices can be integrated with the flexible IC 1020 in a flexible member using the methods illustrated in FIGS. 4-8 as well as other methods.
  • With reference now to FIG. 11, another method of manufacturing CMUT arrays with multiple CMUT elements for a CMUT based ultrasonic system of one embodiment is illustrated. The CMUT arrays illustrated by FIG. 11 can be integrated with the flexible member of an ultrasonic system using semiconductor techniques. More particularly, the CMUT arrays can be fabricated as flexible CMUT arrays and then integrated with the flexible member.
  • Figures at the left side in FIG. 11 show that the multiple CMUT arrays 1110, 1110 a and 1110 b are fabricated in the same substrate 1100. Figures at the right side in FIG. 11 are detailed views of portion of the CMUT array 1110 which show the structure of the CMUT elements 1110-1 and 1110-2 in a CMUT array 1110 in more detail.
  • More specifically, FIG. 11.1 illustrates that flexible CMUT arrays 1110 can be fabricated from a SOI wafer 1100 (including a handling wafer 1103, insulation layer 1102 and the device layer 1101) on which a substrate or bottom electrode 1101, an insulation layer 1102, CMUT arrays 1110 (or CMUT elements), an insulation layer 1131, and various trenches 1170 and 1171 can be fabricated. Each of the CMUT arrays 1110 can include a flexible membrane 1111, a first electrode 1113, a cavity 1116, and a spring anchor 1118 among other possible components. These components 1111, 1113, 1116, and 1118 of the CMUT can be seen in greater detail in the detailed view shown in FIGS. 11.1-11.4. Also, in some embodiments, the CMUTs can be embedded spring ESCMUTs.
  • FIG. 11.2 illustrates that once the CMUT arrays 1110 have been fabricated, a pattern of trenches 1170 (which separate the CMUT from each other) can be fabricated. These trenches 1170 can be sufficiently deep that they reach the insulation layer 1102 which, as discussed herein, can be removed to expose the trenches. In some embodiments, the trenches 1170 and 1171 are formed during the fabrication of the CMUT arrays 1110. At the same time that trenches 1170 are formed, another pattern of trenches 1171 can be fabricated. These trenches 1171 can be formed so that when the insulation layer 1102 is removed, the trenches 1171 are also exposed thereby separating various CMUT arrays 1110 from each other. The trenches 1170 can define the boundaries of individual CMUT transducer elements 1110-1 and 1110-2. The trenched 1171 can define boundaries of individual CMUT transducer arrays 1110, 1110 a and 1110 b on the same wafer.
  • The insulation layer 1131 can be patterned and coated on the wafer 1100 to leave the active surfaces of the CMUT arrays 1110 exposed as illustrated in FIG. 11.2. As the insulation layer 1131 is fabricated, the material from which it is fabricated may fill the trenches 1170 and 1171. The insulation layer 1131 can be made of various semiconductor materials such as Parylene, polyimide, polymer, PDMS, oxide, nitride, etc.
  • FIG. 11.4 illustrates that the insulation layer 1102 can be removed to expose the trenches 1170 and 1171 (which can lie between individual CMUT elements and CMUT arrays 1110, respectively). Thus, the CMUT arrays 1110 can have multiple CMUT elements 1110-1 and 1110-2, can be separated from each other as illustrated by FIG. 11.4. These CMUT arrays 1110 and the CMUT elements can subsequently be integrated on various flexible members such as flexible members 130, 230, and 330 (see FIGS. 1-3) using the methods illustrated in FIGS. 4-8. While FIG. 11 illustrates that the wafer 1100, from which the CMUT arrays 1110 can be fabricated, can be a silicon-on-oxide wafer, other types of wafers can be used to fabricate the CMUT arrays 1110. For instance, a prime wafer can be used to fabricate the CMUT arrays 1110 (or the CMUT elements).
  • FIG. 12 illustrates methods of various embodiments of manufacturing CMUT arrays from prime wafers. More specifically, FIG. 12A illustrates that the trenches 1270 and 1271 can be etched (from the side of the wafer hosting the CMUT arrays 1210) to a selected thickness. Then, in some embodiments, the wafer 1200 can be thinned (from the side which is opposite the CMUT arrays 1110) until the trenches 1170 and 1171 are exposed. Thus, the CMUT arrays 1110 (or CMUT elements) which are hosted on the prime wafer 1100 can be separated from each other.
  • With reference now to FIG. 12B, another method of manufacturing CMUT arrays 1210 of one embodiment is illustrated. In the method illustrated in FIG. 12B, the method can begin with a wafer 1200 which includes an embedded cavity 1208. The CMUT arrays 1210 can be fabricated on regions of the wafer 1200 adjacent to the cavities 1208. The trenches 1270 and 1271 can then be etched into the wafer 1200 and can reach the embedded cavities 1208. Thereafter, in some embodiments, the wafer 1200 can be thinned (e.g., the handling wafer 1203 can be removed) to expose the trenches 1270 and 1271 thereby separating the CMUT arrays 1210 (and the CMUT elements)
  • With reference now to FIG. 12C, another method of manufacturing CMUT arrays 1210 of one embodiment is illustrated. Instead of forming the trenches 1270 and 1271 after finishing CMUT fabrication, the trenches 1270 and 1271 can be formed during the CMUT fabrication. For example, the trenches 1270 and 1271 in FIG. 12C can be etched before the formation of the membrane 1212 and top electrode 1213. According to some embodiments, the trenches embedded under the membrane 1212 can avoid etching the top electrode 1213 and the membrane 1212 during the trench etching in the method illustrated in FIG. 11.2. This may be desirable for the implementation of some CMUT systems. After the CMUT arrays with the embedded trenches 1270 and 1271 are fabricated, the following process can be used to form the flexible CMUT arrays 1210 and is similar to the process illustrated in FIG. 11, FIG. 12A and FIG. 12B.
  • CMUT based ultrasonic scanners provide several advantages over PZT based ultrasonic scanners. These advantages arise, in part, from the relatively low acoustic impedance of CMUTs. CMUTs typically have lower acoustic impedances than air, water, tissue, etc. As a result, and unlike PZTs, CMUTs can be used without a layer of material to match the acoustic impedance of the CMUTs with the acoustic impedance of the surrounding media.
  • PZTs also transmit acoustic energy (i.e., acoustic waves) from both their front and rear surfaces. As a result of this characteristic, PZTs require a backing layer on their rear surface to absorb the acoustic energy emitted there from. Otherwise the acoustic waves transmitted from the rear of the PZTs could reflect from various structures and interfere with the operation of the PZTs. However, in absorbing the acoustic energy transmitted from the rear of the PZTs, the backing layers generate heat. As a result, PZTs can become warm, or even hot, during operation thereby reducing their desirability for use in certain applications such as HIFU. Since CMUTs transmit acoustic energy only from there front surfaces, heating due to misdirected acoustic energy is not a concern for CMUT based ultrasonic scanners. Furthermore, the backing layers (and acoustic matching layers discussed previously) complicate the manufacturing of PZT based ultrasonic systems. In contrast CMUT based ultrasonic systems can omit these layers and the attendant manufacturing steps.
  • Moreover, CMUT based ultrasonic scanners can be produced using semiconductor manufacturing techniques. Since these semiconductor techniques benefit from decades of investments by various portions of the semiconductor industry, these techniques can provide relatively high levels of uniformity, precision, repeatability, dimensional control, repeatability, etc. in the CMUTs thereby produced. Further still, many of the foregoing semiconductor techniques can be batch processes. As a result, economies of scale associated with these techniques allow for lower per unit costs for CMUT based ultrasonic systems, particularly when relatively large volumes of ultrasonic systems may be desired. For instance, since all of the features of the CMUT arrays on a particular wafer can be patterned simultaneously, the fabrication of multiple CMUT arrays introduce no (or little) overhead as compared to the fabrication of a single CMUT array.
  • Additionally, since CMUT based ultrasonic systems can be produced with semiconductor techniques, integrated circuits (ICs) and other semiconductor devices can be integrated with the CMUT arrays with relative ease. Thus, the CMUT arrays and the ICs can be fabricated on the same wafer at the same time using the same techniques. In the alternative, CMUTs and ICs can be integrated into various transducers at different times. Furthermore, CMUTs and ICs can be fabricated from the same, or similar, biocompatible materials.
  • In contrast, the fabrication and integration of PZTs with other components (e.g., ICs) using semiconductor techniques is impracticable due to constraints imposed by the PZT materials Moreover, the available PZT related fabrication and integration techniques suffer from several disadvantages including being labor intensive, being expensive, being subject to manufacturing variations, etc. Furthermore, available PZT techniques meet with additional difficulties as the size of the individual PZT devices approaches the small dimensions (e.g., tens of microns) required for relatively high frequency devices. For instance, separation of the individual PZT devices is dominated by lapping and dicing techniques which lead to device-to-device variability.
  • Accordingly, CMUT based ultrasonic systems enjoy both performance and cost advantages over PZT based ultrasonic systems. More particularly, since it is typically desirable for ultrasonic systems to have transducers with both high frequency operating ranges and small physical sizes, CMUT based ultrasonic systems can have several advantages over PZT based ultrasonic systems.
  • First, CMUT based ultrasonic systems can be fabricated with better dimensional control than PZT based ultrasonic systems. More particularly, CMUT based ultrasonic systems can be fabricated with minimum dimensions less than about 1 micrometer whereas the minimum dimensions of PZT based ultrasonic systems are greater than about 10 micrometers. Accordingly, CMUT based ultrasonic systems can be fabricated with correspondingly smaller CMUT element pitches. Secondly, the minimum width and pitch of CMUT based ultrasonic system interconnects can be less than about 2-3 micrometers whereas the minimum interconnect width and pitch for PZT based ultrasonic systems is greater than about 25 micrometers. Thus, CMUT based ultrasonic system interconnects can be fabricated at higher densities than PZT based ultrasonic system interconnects. Accordingly, CMUT based ultrasound systems can possess more transducers (for a given system size) or can be smaller (for a given number of transducers) than PZT based ultrasonic systems.
  • Moreover, given the improved device size of CMUT based ultrasonic scanners, as compared to PZT based ultrasonic scanners, CMUT based ultrasonic scanners can be created which can operate up to about 100 MHz. In contrast, PZT based ultrasonic scanners are limited to operating regions well below 20 MHz. Furthermore, since the resolution of an ultrasonic transducer depends on its operating frequency, CMUT based ultrasonic scanners can be fabricated with correspondingly improved resolution. For similar reasons, the bandwidth of CMUT based ultrasonic scanners is wider than the bandwidth of PZT based ultrasonic scanners. Accordingly, CMUT based ultrasonic scanners can be applied to more situations than PZT based ultrasonic scanners.
  • The simpler design and fabrication of CMUT based ultrasonic systems (as compared with PZT based ultrasonic transducers) also gives rise to certain advantages. For instance, since the ICs used to support the CMUTs and the CMUTs themselves can be fabricated with the same techniques, fabrication of the CMUTs and ICs, taken together, can be simplified. Additionally, because CMUTs do not require matching or backing layers, the manufacturing steps associated with these layers can also be eliminated. Likewise, steps associated with integrating the CMUTs and the ICs can be eliminated or, if not, simplified.
  • The present disclosure is described with reference to specific embodiments thereof, but those skilled in the art will recognize that the present disclosure is not limited thereto. Various features and aspects of the above-described disclosure may be used individually or jointly. Further, the present disclosure can be utilized in any number of environments and applications beyond those described herein without departing from the broader spirit and scope of the specification. We claim all such modifications and variations that fall within the scope and spirit of the present disclosure. The specification and drawings are, accordingly, to be regarded as illustrative rather than restrictive.

Claims (33)

1. A method of packaging an ultrasonic system, comprising:
integrating an ultrasonic transducer with a flexible member;
integrating an electrical circuit with the flexible member, the integrated electrical circuit, the ultrasonic transducer, and the flexible member being a flexible subassembly; and
shaping the flexible subassembly to have at least one curved part and to be the ultrasonic system.
2. The method of claim 1 wherein the ultrasonic transducer is flexible.
3. The method of claim 1 wherein the electronic device is flexible.
4. The method of claim 1 further comprising integrating the electronic device and the ultrasonic transducer on a device layer of a substrate before integrating the electronic device and the ultrasonic transducer with the flexible member.
5. The method of claim 4 further comprising forming a least a trench through a device layer of a substrate.
6. The method of claim 5 further comprising forming the device layer with at least one embedded cavity.
7. The method of claim 5 further comprising forming the device layer on a SOI wafer.
8. The method of claim 1 further comprising integrating the electronic device and the ultrasonic transducer with the flexible member at the same time.
9. The method of claim 1 wherein the integrating the ultrasonic transducer includes using a semiconductor technique.
10. The method of claim 1 wherein the shaped flexible member defines a lumen or a partial lumen.
11. The method of claim 1 further comprising forming a through wafer interconnect in the ultrasonic transducer and wherein the integrating of the flexible transducer is from the side of the ultrasonic transducer which does not include an active surface of the flexible ultrasonic transducer.
12. The method of claim 1 further comprising attaching the shaped flexible member to a lumen.
13. The method of claim 1 wherein the flexible ultrasonic transducer includes at least one capacitive micromachined ultrasonic transducer (CMUT).
14. The method of claim 1 further comprising folding a portion of the flexible member which hosts the flexible ultrasonic transducer wherein the folded portion of the flexible member and the flexible ultrasonic transducer form a forward looking ultrasonic transducer.
15. The method of claim 1 wherein the flexible ultrasonic transducer includes at least a portion of a circular CMUT array.
16. The method of claim 1 wherein the flexible member includes a pair of arms.
17. The method of claim 1 wherein the integrating of the ultrasonic transducer and the integrating of the electronic circuit are from opposite sides of the flexible member.
18. An ultrasonic system comprising:
an electronic circuit;
an ultrasonic transducer; and
a flexible member with the electronic circuit and the ultrasonic transducer integrated there with, the integrated electronic circuit, the ultrasonic transducer, and the flexible member being a flexible subassembly, the flexible subassembly being shaped to have at least one curved part and being the ultrasonic system.
19. The system of claim 18 wherein the ultrasound transducer is a flexible ultrasound transducer.
20. The system of claim 18 wherein the shaped flexible subassembly is a lumen.
21. The system of claim 18 wherein the flexible ultrasonic transducer includes a through wafer interconnect.
22. The system of claim 18 wherein the ultrasonic transducer includes at least one CMUT element.
23. The system of claim 18 wherein the ultrasonic transducer is a CMUT array including at least two CMUT elements.
24. The system of claim 18 further comprising one of a temperature sensor or pressure sensor integrated with the flexible member.
25. The system of claim 18 wherein the ultrasonic transducer includes at least a portion of a circular CMUT array.
26. The system of claim 18 wherein the ultrasonic transducer is a forward looking ultrasonic transducer.
27. The system of claim 18 wherein the ultrasonic transducer and the electronic circuit are on opposite sides of the flexible member.
28. An ultrasonic system comprising:
an integrated circuit;
a capacitive micromachined ultrasonic transducer (CMUT);
a flexible member with the integrated circuit and the CMUT integrated there with, the integrated circuit, the CMUT, and the flexible member being a flexible subassembly, the flexible subassembly being shaped to have at least one curved part and to be at least a portion of a lumen, the CMUT being positioned on the distal end of the ultrasonic scanner and being a forward looking ring shaped ultrasonic transducer;
29. A method of manufacturing an ultrasonic transducer, the method comprising:
integrating a plurality of ultrasonic transducers and a plurality of electrical circuits with a flexible substrate having interconnections built therein to form a flexible subassembly; and
shaping the flexible subassembly into a compact shape, the shaped flexible subassembly being an ultrasonic transducer.
30. The method of claim 29, wherein the integrating of the plurality of ultrasonic transducers with the flexible substrate comprises:
forming the flexible substrate including the interconnections;
forming a plurality of bonding pads on the flexible substrate, the bonding pads conductively connecting to the interconnections; and
connecting each of the plurality of ultrasonic transducers to a respective one of the plurality of bonding pads.
31. The method of claim 29, wherein the integrating of the plurality of ultrasonic transducers with the flexible substrate comprises:
providing a support substrate;
placing the plurality of ultrasonic transducers onto the support substrate; and
forming the flexible substrate with the interconnections over the plurality of ultrasonic transducers.
32. The method of claim 31, further comprising:
removing at least a part of the support substrate.
33. The method of claim 29, wherein the shaping of the flexible subassembly comprises rolling up the flexible subassembly.
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Cited By (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100225200A1 (en) * 2009-03-05 2010-09-09 Mario Kupnik Monolithic integrated CMUTs fabricated by low-temperature wafer bonding
US20110255249A1 (en) * 2010-04-20 2011-10-20 General Electric Company High density flexible foldable interconnect
US8324006B1 (en) * 2009-10-28 2012-12-04 National Semiconductor Corporation Method of forming a capacitive micromachined ultrasonic transducer (CMUT)
US8563345B2 (en) 2009-10-02 2013-10-22 National Semiconductor Corporated Integration of structurally-stable isolated capacitive micromachined ultrasonic transducer (CMUT) array cells and array elements
US20140005521A1 (en) * 2010-11-18 2014-01-02 Koninklijke Philips Electronics N.V. Catheter comprising capacitive micromachined ultrasonic transducers with an adjustable focus
KR20140035204A (en) * 2012-09-13 2014-03-21 삼성전자주식회사 Micromachined ultrasonic transducer module array
WO2014105725A1 (en) * 2012-12-28 2014-07-03 Volcano Corporation Intravascular ultrasound imaging apparatus, interface architecture, and method of manufacturing
US8852103B2 (en) 2011-10-17 2014-10-07 Butterfly Network, Inc. Transmissive imaging and related apparatus and methods
WO2015028311A1 (en) * 2013-08-26 2015-03-05 Koninklijke Philips N.V. Ultrasound transducer assembly and method for manufacturing an ultrasound transducer assembly
US20150345987A1 (en) * 2014-05-30 2015-12-03 Arman HAJATI Piezoelectric transducer device with flexible substrate
US9221077B2 (en) 2012-05-09 2015-12-29 Kolo Technologies, Inc. CMUT assembly with acoustic window
WO2016008690A1 (en) * 2014-07-17 2016-01-21 Koninklijke Philips N.V. Ultrasound transducer arrangement and assembly, coaxial wire assembly, ultrasound probe and ultrasonic imaging system
WO2016016810A1 (en) * 2014-08-01 2016-02-04 Koninklijke Philips N.V. Intravascular ultrasound imaging apparatus, interface architecture, and method of manufacturing
US9322810B2 (en) 2012-09-11 2016-04-26 Samsung Electronics Co., Ltd. Ultrasonic transducers
US9375850B2 (en) * 2013-02-07 2016-06-28 Fujifilm Dimatix, Inc. Micromachined ultrasonic transducer devices with metal-semiconductor contact for reduced capacitive cross-talk
US9511393B2 (en) 2012-08-17 2016-12-06 The Boeing Company Flexible ultrasound inspection system
WO2017074875A1 (en) * 2015-10-30 2017-05-04 Georgia Tech Research Corporation Foldable 2-d cmut-on-cmos arrays
US9667889B2 (en) 2013-04-03 2017-05-30 Butterfly Network, Inc. Portable electronic devices with integrated imaging capabilities
JP2017514556A (en) * 2014-03-31 2017-06-08 コーニンクレッカ フィリップス エヌ ヴェKoninklijke Philips N.V. IC die, ultrasonic probe, ultrasonic diagnostic system and method
US9789515B2 (en) 2014-05-30 2017-10-17 Fujifilm Dimatix, Inc. Piezoelectric transducer device with lens structures
US20180028159A1 (en) * 2016-07-29 2018-02-01 Butterfly Network, Inc. Rearward acoustic diffusion for ultrasound-on-a-chip transducer array
US10022751B2 (en) 2014-05-30 2018-07-17 Fujifilm Dimatix, Inc. Piezoelectric transducer device for configuring a sequence of operational modes
US10306820B2 (en) 2014-08-21 2019-05-28 Samsung Electronics Co., Ltd. Systems for packaging electronic devices
WO2020112775A1 (en) * 2018-11-28 2020-06-04 Butterfly Network, Inc. Method and apparatus to calibrate ultrasound transducers
WO2021142554A1 (en) * 2020-01-17 2021-07-22 The University Of British Columbia Flexible capacitive micromachined ultrasonic transducer arrays
KR20220021250A (en) * 2020-08-13 2022-02-22 한국과학기술연구원 Flexible ultrasound transducer and method for manufacturing the same
US11413008B2 (en) 2017-06-30 2022-08-16 Koninklijke Philips N.V. Intraluminal ultrasound imaging device comprising a substrate separated into a plurality of spaced-apart segments, intraluminal ultrasound imaging device comprising a trench, and method of manufacturing
US20220313205A1 (en) * 2021-04-05 2022-10-06 GE Precision Healthcare LLC Methods and systems for an invasive deployable device

Families Citing this family (58)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2009239424B9 (en) 2008-04-21 2014-10-09 Covidien Lp Braid-ball embolic devices and delivery systems
US9675482B2 (en) 2008-05-13 2017-06-13 Covidien Lp Braid implant delivery systems
US8545412B2 (en) * 2009-05-29 2013-10-01 Boston Scientific Scimed, Inc. Systems and methods for making and using image-guided intravascular and endocardial therapy systems
WO2011039723A1 (en) * 2009-09-30 2011-04-07 Paul Anthony Yuen Performance monitoring apparatus and casing therefor
US8998947B2 (en) 2010-09-10 2015-04-07 Medina Medical, Inc. Devices and methods for the treatment of vascular defects
JP6087281B2 (en) 2010-09-10 2017-03-01 メディナ メディカル,インコーポレイテッド Device and method for treating vascular abnormalities
US8696581B2 (en) 2010-10-18 2014-04-15 CardioSonic Ltd. Ultrasound transducer and uses thereof
US9310485B2 (en) 2011-05-12 2016-04-12 Georgia Tech Research Corporation Compact, energy-efficient ultrasound imaging probes using CMUT arrays with integrated electronics
CN102793568B (en) * 2011-05-23 2014-12-10 香港理工大学 Annular-array ultrasonic endoscope probe, preparation method thereof and fixing rotating device
US9271696B2 (en) * 2011-09-22 2016-03-01 Boston Scientific Scimed, Inc. Ultrasound imaging systems with bias circuitry and methods of making and using
CN104349818B (en) * 2012-04-12 2018-05-15 皇家飞利浦有限公司 Medical instrument and its control method with capacitive character micromechanics transducer
KR101383298B1 (en) 2012-04-25 2014-04-09 삼성전자주식회사 Ultrasonic probe apparatus and method for fabricating ultrasonic probe apparatus
US11357447B2 (en) 2012-05-31 2022-06-14 Sonivie Ltd. Method and/or apparatus for measuring renal denervation effectiveness
US9113825B2 (en) * 2012-07-10 2015-08-25 Fujifilm Sonosite, Inc. Ultrasonic probe and aligned needle guide system
KR102309795B1 (en) 2012-11-13 2021-10-08 코비디엔 엘피 Occlusive devices
US20140257262A1 (en) * 2013-03-11 2014-09-11 Alexandre Carpentier Interstitial ultrasonic disposable applicator and method for tissue thermal conformal volume ablation and monitoring the same
US10933259B2 (en) * 2013-05-23 2021-03-02 CardioSonic Ltd. Devices and methods for renal denervation and assessment thereof
US20150082890A1 (en) * 2013-09-26 2015-03-26 Intel Corporation Biometric sensors for personal devices
JP6221582B2 (en) * 2013-09-30 2017-11-01 セイコーエプソン株式会社 Ultrasonic device and probe, electronic apparatus and ultrasonic imaging apparatus
WO2015071051A1 (en) * 2013-11-15 2015-05-21 Koninklijke Philips N.V. Integrated circuit array and method for manufacturing an array of integrated circuits
WO2015135784A2 (en) 2014-03-12 2015-09-17 Koninklijke Philips N.V. Ultrasound transducer assembly and method for manufacturing an ultrasound transducer assembly
EP3142564A4 (en) * 2014-04-11 2017-07-19 Koninklijke Philips N.V. Imaging and treatment device
WO2015164301A1 (en) * 2014-04-23 2015-10-29 Koninklijke Philips N.V. Catheter with integrated controller for imaging and pressure sensing
WO2015169771A1 (en) * 2014-05-06 2015-11-12 Koninklijke Philips N.V. Ultrasonic transducer chip assembly, ultrasound probe, ultrasonic imaging system and ultrasound assembly and probe manufacturing methods
CN103976743A (en) * 2014-05-27 2014-08-13 江西科技师范大学 CMUT (Capacitive Micro-machined Ultrasonic Transducer) annular array based micro-photoacoustic transducer
JP6606171B2 (en) * 2014-08-28 2019-11-13 コーニンクレッカ フィリップス エヌ ヴェ Intravascular device with reinforced fast exchange port and associated system
CN105769255A (en) * 2014-12-25 2016-07-20 乐普(北京)医疗器械股份有限公司 Monocrystal multi-acoustic-beam transducer ablation device
US9375333B1 (en) 2015-03-06 2016-06-28 Covidien Lp Implantable device detachment systems and associated devices and methods
US11766237B2 (en) 2015-07-02 2023-09-26 Philips Image Guided Therapy Corporation Multi-mode capacitive micromachined ultrasound transducer and associated devices, systems, and methods for multiple different intravascular sensing capabilities
US10413938B2 (en) 2015-11-18 2019-09-17 Kolo Medical, Ltd. Capacitive micromachined ultrasound transducers having varying properties
US10413272B2 (en) 2016-03-08 2019-09-17 Covidien Lp Surgical tool with flex circuit ultrasound sensor
US11446000B2 (en) 2016-03-30 2022-09-20 Philips Image Guided Therapy Corporation Standalone flex circuit for intravascular imaging device and associated devices, systems, and methods
CN105852911B (en) * 2016-05-26 2019-11-29 苏州佳世达电通有限公司 Supersonic waveguide and medical system
US10618078B2 (en) 2016-07-18 2020-04-14 Kolo Medical, Ltd. Bias control for capacitive micromachined ultrasonic transducers
US10478195B2 (en) 2016-08-04 2019-11-19 Covidien Lp Devices, systems, and methods for the treatment of vascular defects
US10399121B2 (en) 2016-09-12 2019-09-03 Kolo Medical, Ltd. Bias application for capacitive micromachined ultrasonic transducers
KR101915255B1 (en) 2017-01-11 2018-11-05 삼성메디슨 주식회사 Method of manufacturing the ultrasonic probe and the ultrasonic probe
EP3369383A1 (en) * 2017-03-02 2018-09-05 Koninklijke Philips N.V. Ultrasound device
JP7199369B2 (en) * 2017-03-07 2023-01-05 コーニンクレッカ フィリップス エヌ ヴェ Imaging assembly for intraluminal imaging
EP3600434A4 (en) 2017-03-20 2021-01-06 Sonievie Ltd. Pulmonary hypertension treatment
US20180345046A1 (en) * 2017-05-30 2018-12-06 David A. Gallup Catheter and method for use
US10613058B2 (en) 2017-06-27 2020-04-07 Kolo Medical, Ltd. CMUT signal separation with multi-level bias control
US10675036B2 (en) 2017-08-22 2020-06-09 Covidien Lp Devices, systems, and methods for the treatment of vascular defects
CN111065340B (en) 2017-09-28 2022-09-20 波士顿科学国际有限公司 System and method for adjusting signal path along intravascular ultrasound imaging system based on frequency
JP2021505263A (en) * 2017-12-08 2021-02-18 コーニンクレッカ フィリップス エヌ ヴェKoninklijke Philips N.V. Retractable flexible substrate with integrated window for intracavitary ultrasound imaging
CN111479512A (en) * 2017-12-08 2020-07-31 皇家飞利浦有限公司 Coiled flexible substrate for intraluminal ultrasound imaging devices
WO2019115424A1 (en) * 2017-12-12 2019-06-20 Koninklijke Philips N.V. Intraluminal ultrasound scanner with reduced diameter
CN108175441A (en) * 2017-12-28 2018-06-19 业成科技(成都)有限公司 Ultrasonic sensing device
EP3542723A1 (en) * 2018-03-23 2019-09-25 Koninklijke Philips N.V. Medical device and system for blood flow measurement
CN109171816B (en) * 2018-09-05 2021-07-20 中北大学 Ultrasonic CT system for examining mammary gland and scanning method thereof
CN109589132A (en) * 2018-10-16 2019-04-09 天津大学 The capacitive micromachined ultrasound transducer array of adjustable focal length based on flexible substrate
US11129621B2 (en) 2018-12-17 2021-09-28 Covidien Lp Devices, systems, and methods for the treatment of vascular defects
EP4041090A1 (en) * 2019-10-08 2022-08-17 Koninklijke Philips N.V. Intraluminal ultrasound assembly having a multiple material support member, and associated devices, systems, and methods
CN114630627A (en) 2019-11-04 2022-06-14 柯惠有限合伙公司 Devices, systems, and methods for treating intracranial aneurysms
CN110849539B (en) * 2019-11-27 2021-04-06 中国航空工业集团公司北京长城计量测试技术研究所 Calibration device for pressure measurement system with tube cavity
US11931041B2 (en) 2020-05-12 2024-03-19 Covidien Lp Devices, systems, and methods for the treatment of vascular defects
CN114871083B (en) * 2022-05-22 2023-07-11 中北大学 Flexible cylindrical array of capacitive micromachined ultrasonic transducer and preparation method thereof
CN116269639A (en) * 2023-03-14 2023-06-23 上海心弘生命科学有限公司 Ultrasonic guide core and ultrasonic thrombolysis device

Citations (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4413520A (en) * 1980-06-16 1983-11-08 Fujitsu Limited Ultrasonic imaging apparatus
US4603589A (en) * 1983-12-27 1986-08-05 Kabushiki Kaisha Toshiba Ultrasonic flowmeter
US5488954A (en) * 1994-09-09 1996-02-06 Georgia Tech Research Corp. Ultrasonic transducer and method for using same
US5870351A (en) * 1994-10-21 1999-02-09 The Board Of Trustees Of The Leland Stanford Junior University Broadband microfabriated ultrasonic transducer and method of fabrication
US5872536A (en) * 1997-02-19 1999-02-16 Hittite Microwave Corporation Multi-sensor anticipatory object detection system
US5906580A (en) * 1997-05-05 1999-05-25 Creare Inc. Ultrasound system and method of administering ultrasound including a plurality of multi-layer transducer elements
US5957851A (en) * 1996-06-10 1999-09-28 Acuson Corporation Extended bandwidth ultrasonic transducer
US6493288B2 (en) * 1999-12-17 2002-12-10 The Board Of Trustees Of The Leland Stanford Junior University Wide frequency band micromachined capacitive microphone/hydrophone and method
US6558330B1 (en) * 2000-12-06 2003-05-06 Acuson Corporation Stacked and filled capacitive microelectromechanical ultrasonic transducer for medical diagnostic ultrasound systems
US6558331B1 (en) * 2002-05-29 2003-05-06 Koninklijke Philips Electronics N.V. Apparatus and method for harmonic imaging using an array transducer operated in the k31 mode
US6632178B1 (en) * 2000-06-15 2003-10-14 Koninklijke Philips Electronics N.V. Fabrication of capacitive micromachined ultrasonic transducers by micro-stereolithography
US20030236443A1 (en) * 2002-04-19 2003-12-25 Cespedes Eduardo Ignacio Methods and apparatus for the identification and stabilization of vulnerable plaque
US6709392B1 (en) * 2002-10-10 2004-03-23 Koninklijke Philips Electronics N.V. Imaging ultrasound transducer temperature control system and method using feedback
US20040085858A1 (en) * 2002-08-08 2004-05-06 Khuri-Yakub Butrus T. Micromachined ultrasonic transducers and method of fabrication
US6776763B2 (en) * 1994-03-11 2004-08-17 Volcano Therapeutic, Inc. Ultrasonic transducer array and method of manufacturing the same
US20040229830A1 (en) * 1995-03-05 2004-11-18 Katsuro Tachibana Delivery of therapeutic compositions using ultrasound
US20050004466A1 (en) * 2003-07-02 2005-01-06 Hynynen Kullvero H. Harmonic motion imaging
US20050015009A1 (en) * 2000-11-28 2005-01-20 Allez Physionix , Inc. Systems and methods for determining intracranial pressure non-invasively and acoustic transducer assemblies for use in such systems
US6854338B2 (en) * 2000-07-14 2005-02-15 The Board Of Trustees Of The Leland Stanford Junior University Fluidic device with integrated capacitive micromachined ultrasonic transducers
US20050137812A1 (en) * 2003-12-22 2005-06-23 Joe Schaffer Ultrasonic flowmeter
US20050177045A1 (en) * 2004-02-06 2005-08-11 Georgia Tech Research Corporation cMUT devices and fabrication methods
US20050197574A1 (en) * 1997-01-08 2005-09-08 Volcano Corporation Ultrasound transducer array having a flexible substrate
US6945115B1 (en) * 2004-03-04 2005-09-20 General Mems Corporation Micromachined capacitive RF pressure sensor
US20050288873A1 (en) * 2004-06-28 2005-12-29 Nelson Urdaneta Ultrasonic liquid flow controller
US20060004289A1 (en) * 2004-06-30 2006-01-05 Wei-Cheng Tian High sensitivity capacitive micromachined ultrasound transducer
US20060084875A1 (en) * 2004-10-14 2006-04-20 Scimed Life Systems, Inc. Integrated bias circuitry for ultrasound imaging devices
US20060229659A1 (en) * 2004-12-09 2006-10-12 The Foundry, Inc. Aortic valve repair
US20070013269A1 (en) * 2005-06-17 2007-01-18 Yongli Huang Flexible micro-electro-mechanical transducer
US20070066902A1 (en) * 2005-09-22 2007-03-22 Siemens Medical Solutions Usa, Inc. Expandable ultrasound transducer array
US20070093702A1 (en) * 2005-10-26 2007-04-26 Skyline Biomedical, Inc. Apparatus and method for non-invasive and minimally-invasive sensing of parameters relating to blood
US7212787B2 (en) * 2001-11-29 2007-05-01 Nasaco Electronics (Hong Kong) Ltd. Wireless audio transmission system
US20070096181A1 (en) * 2005-10-27 2007-05-03 Optimum Care International Tech. Inc. Flexible memory module
US7213468B2 (en) * 2003-04-21 2007-05-08 Teijin Pharma Limited Ultrasonic apparatus and method for measuring the concentration and flow rate of gas
US20070153632A1 (en) * 2006-01-04 2007-07-05 Industrial Technology Research Institute Capacitive ultrasonic transducer and method of fabricating the same
US20070167812A1 (en) * 2004-09-15 2007-07-19 Lemmerhirt David F Capacitive Micromachined Ultrasonic Transducer
US7305883B2 (en) * 2005-10-05 2007-12-11 The Board Of Trustees Of The Leland Stanford Junior University Chemical micromachined microsensors
US7408283B2 (en) * 2003-12-29 2008-08-05 General Electric Company Micromachined ultrasonic transducer cells having compliant support structure
US20090219743A1 (en) * 1997-04-04 2009-09-03 Leedy Glenn J Three dimensional structure memory
US20100013574A1 (en) * 2005-08-03 2010-01-21 Kolo Technologies, Inc. Micro-Electro-Mechanical Transducer Having a Surface Plate
US20100160786A1 (en) * 2007-06-01 2010-06-24 Koninklijke Philips Electronics N.V. Wireless Ultrasound Probe User Interface

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7226417B1 (en) * 1995-12-26 2007-06-05 Volcano Corporation High resolution intravascular ultrasound transducer assembly having a flexible substrate
JP4274850B2 (en) * 2003-05-15 2009-06-10 テルモ株式会社 catheter
JP2004350701A (en) * 2003-05-26 2004-12-16 Olympus Corp Ultrasonic endoscope apparatus
JP4379576B2 (en) 2003-08-04 2009-12-09 株式会社日立メディコ Ultrasonic diagnostic equipment
JP4347885B2 (en) 2004-06-03 2009-10-21 オリンパス株式会社 Manufacturing method of capacitive ultrasonic transducer, ultrasonic endoscope apparatus including capacitive ultrasonic transducer manufactured by the manufacturing method, capacitive ultrasonic probe, and capacitive ultrasonic transducer Sonic transducer
EP1762182B1 (en) * 2004-06-10 2011-08-03 Olympus Corporation Electrostatic capacity type ultrasonic probe device
JP4624763B2 (en) * 2004-10-27 2011-02-02 オリンパス株式会社 Capacitive ultrasonic transducer and manufacturing method thereof
US7375420B2 (en) 2004-12-03 2008-05-20 General Electric Company Large area transducer array
US7449821B2 (en) * 2005-03-02 2008-11-11 Research Triangle Institute Piezoelectric micromachined ultrasonic transducer with air-backed cavities
EP1882127A2 (en) 2005-05-18 2008-01-30 Kolo Technologies, Inc. Micro-electro-mechanical transducers
JP4776349B2 (en) 2005-11-14 2011-09-21 株式会社日立メディコ Ultrasonic imaging device
US20070167821A1 (en) * 2005-11-30 2007-07-19 Warren Lee Rotatable transducer array for volumetric ultrasound
JP4839099B2 (en) 2006-03-03 2011-12-14 オリンパスメディカルシステムズ株式会社 Ultrasonic transducer manufactured by micromachine process, ultrasonic transducer device, ultrasonic diagnostic device in body cavity, and control method thereof
JP2007251505A (en) 2006-03-15 2007-09-27 Fuji Xerox Co Ltd Ultrasonic probe, array probe, and method of manufacturing ultrasonic probe
JP2007244638A (en) 2006-03-16 2007-09-27 Matsushita Electric Ind Co Ltd Ultrasonograph
JP4958475B2 (en) 2006-05-19 2012-06-20 株式会社日立メディコ Ultrasonic device

Patent Citations (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4413520A (en) * 1980-06-16 1983-11-08 Fujitsu Limited Ultrasonic imaging apparatus
US4603589A (en) * 1983-12-27 1986-08-05 Kabushiki Kaisha Toshiba Ultrasonic flowmeter
US6776763B2 (en) * 1994-03-11 2004-08-17 Volcano Therapeutic, Inc. Ultrasonic transducer array and method of manufacturing the same
US5488954A (en) * 1994-09-09 1996-02-06 Georgia Tech Research Corp. Ultrasonic transducer and method for using same
US5870351A (en) * 1994-10-21 1999-02-09 The Board Of Trustees Of The Leland Stanford Junior University Broadband microfabriated ultrasonic transducer and method of fabrication
US20040229830A1 (en) * 1995-03-05 2004-11-18 Katsuro Tachibana Delivery of therapeutic compositions using ultrasound
US5957851A (en) * 1996-06-10 1999-09-28 Acuson Corporation Extended bandwidth ultrasonic transducer
US20050197574A1 (en) * 1997-01-08 2005-09-08 Volcano Corporation Ultrasound transducer array having a flexible substrate
US5872536A (en) * 1997-02-19 1999-02-16 Hittite Microwave Corporation Multi-sensor anticipatory object detection system
US20090219743A1 (en) * 1997-04-04 2009-09-03 Leedy Glenn J Three dimensional structure memory
US5906580A (en) * 1997-05-05 1999-05-25 Creare Inc. Ultrasound system and method of administering ultrasound including a plurality of multi-layer transducer elements
US6493288B2 (en) * 1999-12-17 2002-12-10 The Board Of Trustees Of The Leland Stanford Junior University Wide frequency band micromachined capacitive microphone/hydrophone and method
US6632178B1 (en) * 2000-06-15 2003-10-14 Koninklijke Philips Electronics N.V. Fabrication of capacitive micromachined ultrasonic transducers by micro-stereolithography
US6854338B2 (en) * 2000-07-14 2005-02-15 The Board Of Trustees Of The Leland Stanford Junior University Fluidic device with integrated capacitive micromachined ultrasonic transducers
US20050015009A1 (en) * 2000-11-28 2005-01-20 Allez Physionix , Inc. Systems and methods for determining intracranial pressure non-invasively and acoustic transducer assemblies for use in such systems
US6558330B1 (en) * 2000-12-06 2003-05-06 Acuson Corporation Stacked and filled capacitive microelectromechanical ultrasonic transducer for medical diagnostic ultrasound systems
US7212787B2 (en) * 2001-11-29 2007-05-01 Nasaco Electronics (Hong Kong) Ltd. Wireless audio transmission system
US20030236443A1 (en) * 2002-04-19 2003-12-25 Cespedes Eduardo Ignacio Methods and apparatus for the identification and stabilization of vulnerable plaque
US6558331B1 (en) * 2002-05-29 2003-05-06 Koninklijke Philips Electronics N.V. Apparatus and method for harmonic imaging using an array transducer operated in the k31 mode
US20040085858A1 (en) * 2002-08-08 2004-05-06 Khuri-Yakub Butrus T. Micromachined ultrasonic transducers and method of fabrication
US6958255B2 (en) * 2002-08-08 2005-10-25 The Board Of Trustees Of The Leland Stanford Junior University Micromachined ultrasonic transducers and method of fabrication
US6709392B1 (en) * 2002-10-10 2004-03-23 Koninklijke Philips Electronics N.V. Imaging ultrasound transducer temperature control system and method using feedback
US7213468B2 (en) * 2003-04-21 2007-05-08 Teijin Pharma Limited Ultrasonic apparatus and method for measuring the concentration and flow rate of gas
US20050004466A1 (en) * 2003-07-02 2005-01-06 Hynynen Kullvero H. Harmonic motion imaging
US20050137812A1 (en) * 2003-12-22 2005-06-23 Joe Schaffer Ultrasonic flowmeter
US7408283B2 (en) * 2003-12-29 2008-08-05 General Electric Company Micromachined ultrasonic transducer cells having compliant support structure
US20050177045A1 (en) * 2004-02-06 2005-08-11 Georgia Tech Research Corporation cMUT devices and fabrication methods
US6945115B1 (en) * 2004-03-04 2005-09-20 General Mems Corporation Micromachined capacitive RF pressure sensor
US20050288873A1 (en) * 2004-06-28 2005-12-29 Nelson Urdaneta Ultrasonic liquid flow controller
US20060004289A1 (en) * 2004-06-30 2006-01-05 Wei-Cheng Tian High sensitivity capacitive micromachined ultrasound transducer
US20070167812A1 (en) * 2004-09-15 2007-07-19 Lemmerhirt David F Capacitive Micromachined Ultrasonic Transducer
US20060084875A1 (en) * 2004-10-14 2006-04-20 Scimed Life Systems, Inc. Integrated bias circuitry for ultrasound imaging devices
US20060229659A1 (en) * 2004-12-09 2006-10-12 The Foundry, Inc. Aortic valve repair
US20070013269A1 (en) * 2005-06-17 2007-01-18 Yongli Huang Flexible micro-electro-mechanical transducer
US7880565B2 (en) * 2005-08-03 2011-02-01 Kolo Technologies, Inc. Micro-electro-mechanical transducer having a surface plate
US8018301B2 (en) * 2005-08-03 2011-09-13 Kolo Technologies, Inc. Micro-electro-mechanical transducer having a surface plate
US20100013574A1 (en) * 2005-08-03 2010-01-21 Kolo Technologies, Inc. Micro-Electro-Mechanical Transducer Having a Surface Plate
US20110136284A1 (en) * 2005-08-03 2011-06-09 Kolo Technologies, Inc. Micro-Electro-Mechanical Transducer Having a Surface Plate
US20070066902A1 (en) * 2005-09-22 2007-03-22 Siemens Medical Solutions Usa, Inc. Expandable ultrasound transducer array
US7305883B2 (en) * 2005-10-05 2007-12-11 The Board Of Trustees Of The Leland Stanford Junior University Chemical micromachined microsensors
US20070093702A1 (en) * 2005-10-26 2007-04-26 Skyline Biomedical, Inc. Apparatus and method for non-invasive and minimally-invasive sensing of parameters relating to blood
US20070096181A1 (en) * 2005-10-27 2007-05-03 Optimum Care International Tech. Inc. Flexible memory module
US20070153632A1 (en) * 2006-01-04 2007-07-05 Industrial Technology Research Institute Capacitive ultrasonic transducer and method of fabricating the same
US20100160786A1 (en) * 2007-06-01 2010-06-24 Koninklijke Philips Electronics N.V. Wireless Ultrasound Probe User Interface

Cited By (58)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8402831B2 (en) * 2009-03-05 2013-03-26 The Board Of Trustees Of The Leland Standford Junior University Monolithic integrated CMUTs fabricated by low-temperature wafer bonding
US20100225200A1 (en) * 2009-03-05 2010-09-09 Mario Kupnik Monolithic integrated CMUTs fabricated by low-temperature wafer bonding
US8563345B2 (en) 2009-10-02 2013-10-22 National Semiconductor Corporated Integration of structurally-stable isolated capacitive micromachined ultrasonic transducer (CMUT) array cells and array elements
US8324006B1 (en) * 2009-10-28 2012-12-04 National Semiconductor Corporation Method of forming a capacitive micromachined ultrasonic transducer (CMUT)
US20110255249A1 (en) * 2010-04-20 2011-10-20 General Electric Company High density flexible foldable interconnect
US9986916B2 (en) * 2010-11-18 2018-06-05 Koninklijke Philips N.V. Catheter comprising capacitive micromachined ultrasonic transducers with an adjustable focus
US20140005521A1 (en) * 2010-11-18 2014-01-02 Koninklijke Philips Electronics N.V. Catheter comprising capacitive micromachined ultrasonic transducers with an adjustable focus
EP2640466B1 (en) * 2010-11-18 2020-03-04 Koninklijke Philips N.V. Catheter comprising capacitive micromachined ultrasonic transducers with an adjustable focus
US9247924B2 (en) 2011-10-17 2016-02-02 Butterfly Networks, Inc. Transmissive imaging and related apparatus and methods
US9198637B2 (en) 2011-10-17 2015-12-01 Butterfly Network, Inc. Transmissive imaging and related apparatus and methods
US9268015B2 (en) 2011-10-17 2016-02-23 Butterfly Network, Inc. Image-guided high intensity focused ultrasound and related apparatus and methods
US9149255B2 (en) 2011-10-17 2015-10-06 Butterfly Network, Inc. Image-guided high intensity focused ultrasound and related apparatus and methods
US9033884B2 (en) 2011-10-17 2015-05-19 Butterfly Network, Inc. Transmissive imaging and related apparatus and methods
US9028412B2 (en) 2011-10-17 2015-05-12 Butterfly Network, Inc. Transmissive imaging and related apparatus and methods
US9155521B2 (en) 2011-10-17 2015-10-13 Butterfly Network, Inc. Transmissive imaging and related apparatus and methods
US9022936B2 (en) 2011-10-17 2015-05-05 Butterfly Network, Inc. Transmissive imaging and related apparatus and methods
US8852103B2 (en) 2011-10-17 2014-10-07 Butterfly Network, Inc. Transmissive imaging and related apparatus and methods
US9268014B2 (en) 2011-10-17 2016-02-23 Butterfly Network, Inc. Transmissive imaging and related apparatus and methods
US9221077B2 (en) 2012-05-09 2015-12-29 Kolo Technologies, Inc. CMUT assembly with acoustic window
US9975146B2 (en) 2012-05-09 2018-05-22 Kolo Technologies, Inc. CMUT assembly with acoustic window
US9662679B2 (en) 2012-05-09 2017-05-30 Kolo Technologies, Inc. CMUT assembly with acoustic window
US9511393B2 (en) 2012-08-17 2016-12-06 The Boeing Company Flexible ultrasound inspection system
US9322810B2 (en) 2012-09-11 2016-04-26 Samsung Electronics Co., Ltd. Ultrasonic transducers
KR20140035204A (en) * 2012-09-13 2014-03-21 삼성전자주식회사 Micromachined ultrasonic transducer module array
US9233396B2 (en) 2012-09-13 2016-01-12 Samsung Electronics Co., Ltd. Micromachined ultrasonic transducer array
US10555720B2 (en) 2012-12-28 2020-02-11 Volcano Corporation Intravascular ultrasound imaging apparatus, interface, architecture, and method of manufacturing
US11759169B2 (en) 2012-12-28 2023-09-19 Philips Image Guided Therapy Corporation Intravascular ultrasound imaging apparatus, interface architecture, and method of manufacturing
US10674996B2 (en) 2012-12-28 2020-06-09 Philips Image Guided Therapy Corporation Intravascular ultrasound imaging apparatus, interface architecture, and method of manufacturing
WO2014105725A1 (en) * 2012-12-28 2014-07-03 Volcano Corporation Intravascular ultrasound imaging apparatus, interface architecture, and method of manufacturing
US10575815B2 (en) 2012-12-28 2020-03-03 Philips Image Guided Therapy Corporation Intravascular ultrasound imaging apparatus, interface architecture, and method of manufacturing
US9375850B2 (en) * 2013-02-07 2016-06-28 Fujifilm Dimatix, Inc. Micromachined ultrasonic transducer devices with metal-semiconductor contact for reduced capacitive cross-talk
US9667889B2 (en) 2013-04-03 2017-05-30 Butterfly Network, Inc. Portable electronic devices with integrated imaging capabilities
WO2015028311A1 (en) * 2013-08-26 2015-03-05 Koninklijke Philips N.V. Ultrasound transducer assembly and method for manufacturing an ultrasound transducer assembly
JP2016529834A (en) * 2013-08-26 2016-09-23 コーニンクレッカ フィリップス エヌ ヴェKoninklijke Philips N.V. Ultrasonic transducer assembly and method for manufacturing an ultrasonic transducer assembly
US11407008B2 (en) 2013-08-26 2022-08-09 Koninklijke Philips N.V. Ultrasound transducer assembly and method for manufacturing an ultrasound transducer assembly
JP2017514556A (en) * 2014-03-31 2017-06-08 コーニンクレッカ フィリップス エヌ ヴェKoninklijke Philips N.V. IC die, ultrasonic probe, ultrasonic diagnostic system and method
US9789515B2 (en) 2014-05-30 2017-10-17 Fujifilm Dimatix, Inc. Piezoelectric transducer device with lens structures
US20150345987A1 (en) * 2014-05-30 2015-12-03 Arman HAJATI Piezoelectric transducer device with flexible substrate
US10022751B2 (en) 2014-05-30 2018-07-17 Fujifilm Dimatix, Inc. Piezoelectric transducer device for configuring a sequence of operational modes
US10107645B2 (en) * 2014-05-30 2018-10-23 Fujifilm Dimatix, Inc. Piezoelectric transducer device with flexible substrate
US10828673B2 (en) 2014-07-17 2020-11-10 Koninklijke Philips N.V. Ultrasound transducer arrangement and assembly, coaxial wire assembly, ultrasound probe and ultrasonic imaging system
WO2016008690A1 (en) * 2014-07-17 2016-01-21 Koninklijke Philips N.V. Ultrasound transducer arrangement and assembly, coaxial wire assembly, ultrasound probe and ultrasonic imaging system
JP2017528178A (en) * 2014-07-17 2017-09-28 コーニンクレッカ フィリップス エヌ ヴェKoninklijke Philips N.V. Ultrasonic transducer device and assembly, coaxial wire assembly, ultrasonic probe, and ultrasonic imaging system
EP3795262A1 (en) 2014-07-17 2021-03-24 Koninklijke Philips N.V. Ultrasound transducer arrangement
US20160029999A1 (en) * 2014-08-01 2016-02-04 Volcano Corporation Intravascular Ultrasound Imaging Apparatus, Interface Architecture, and Method of Manufacturing
WO2016016810A1 (en) * 2014-08-01 2016-02-04 Koninklijke Philips N.V. Intravascular ultrasound imaging apparatus, interface architecture, and method of manufacturing
US11224403B2 (en) * 2014-08-01 2022-01-18 Philips Image Guided Therapy Corporation Intravascular ultrasound imaging apparatus, interface architecture, and method of manufacturing
US10306820B2 (en) 2014-08-21 2019-05-28 Samsung Electronics Co., Ltd. Systems for packaging electronic devices
WO2017074875A1 (en) * 2015-10-30 2017-05-04 Georgia Tech Research Corporation Foldable 2-d cmut-on-cmos arrays
US11660073B2 (en) 2015-10-30 2023-05-30 Georgia Tech Research Corporation Foldable 2-D CMUT-on-CMOS arrays
US20180028159A1 (en) * 2016-07-29 2018-02-01 Butterfly Network, Inc. Rearward acoustic diffusion for ultrasound-on-a-chip transducer array
US11413008B2 (en) 2017-06-30 2022-08-16 Koninklijke Philips N.V. Intraluminal ultrasound imaging device comprising a substrate separated into a plurality of spaced-apart segments, intraluminal ultrasound imaging device comprising a trench, and method of manufacturing
US11883233B2 (en) 2017-06-30 2024-01-30 Koninklijke Philips N.V. Intraluminal ultrasound imaging device comprising a substrate separated into a plurality of spaced-apart segments, intraluminal ultrasound imaging device comprising a trench, and method of manufacturing
WO2020112775A1 (en) * 2018-11-28 2020-06-04 Butterfly Network, Inc. Method and apparatus to calibrate ultrasound transducers
WO2021142554A1 (en) * 2020-01-17 2021-07-22 The University Of British Columbia Flexible capacitive micromachined ultrasonic transducer arrays
KR20220021250A (en) * 2020-08-13 2022-02-22 한국과학기술연구원 Flexible ultrasound transducer and method for manufacturing the same
KR102610342B1 (en) * 2020-08-13 2023-12-07 한국과학기술연구원 Flexible ultrasound transducer and method for manufacturing the same
US20220313205A1 (en) * 2021-04-05 2022-10-06 GE Precision Healthcare LLC Methods and systems for an invasive deployable device

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