US20100262032A1 - Systems and Methods for Indicating Aberrant Behavior Detected by an Implanted Medical Device - Google Patents
Systems and Methods for Indicating Aberrant Behavior Detected by an Implanted Medical Device Download PDFInfo
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- US20100262032A1 US20100262032A1 US12/822,477 US82247710A US2010262032A1 US 20100262032 A1 US20100262032 A1 US 20100262032A1 US 82247710 A US82247710 A US 82247710A US 2010262032 A1 US2010262032 A1 US 2010262032A1
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/48—Other medical applications
- A61B5/4806—Sleep evaluation
- A61B5/4818—Sleep apnoea
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0002—Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network
- A61B5/0031—Implanted circuitry
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- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
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- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/372—Arrangements in connection with the implantation of stimulators
- A61N1/37211—Means for communicating with stimulators
- A61N1/37252—Details of algorithms or data aspects of communication system, e.g. handshaking, transmitting specific data or segmenting data
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/08—Detecting, measuring or recording devices for evaluating the respiratory organs
- A61B5/0816—Measuring devices for examining respiratory frequency
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- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/103—Detecting, measuring or recording devices for testing the shape, pattern, colour, size or movement of the body or parts thereof, for diagnostic purposes
- A61B5/11—Measuring movement of the entire body or parts thereof, e.g. head or hand tremor, mobility of a limb
- A61B5/113—Measuring movement of the entire body or parts thereof, e.g. head or hand tremor, mobility of a limb occurring during breathing
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- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/3601—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation of respiratory organs
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/362—Heart stimulators
- A61N1/3621—Heart stimulators for treating or preventing abnormally high heart rate
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/372—Arrangements in connection with the implantation of stimulators
- A61N1/37211—Means for communicating with stimulators
- A61N1/37252—Details of algorithms or data aspects of communication system, e.g. handshaking, transmitting specific data or segmenting data
- A61N1/37258—Alerting the patient
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/372—Arrangements in connection with the implantation of stimulators
- A61N1/37211—Means for communicating with stimulators
- A61N1/37252—Details of algorithms or data aspects of communication system, e.g. handshaking, transmitting specific data or segmenting data
- A61N1/37282—Details of algorithms or data aspects of communication system, e.g. handshaking, transmitting specific data or segmenting data characterised by communication with experts in remote locations using a network
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Abstract
Various systems and methods provide for intervening where aberrant heart and/or respiratory functionality is detected. For example, some embodiments of the present invention provide a monitor capable of detecting the occurrence of various aberrant events, and in some cases for intervening in the event. In some cases, a pacemaker or some other medical device detects an abnormality, and an information signal indicating the detected abnormality is transmitted from the pacemaker to a bedside monitor or some other monitor associated with the patient. Based on the received information signal, the bedside monitor can deliver an appropriate therapy. Such a therapy can be, but are not limited to, the sounding of an audible alarm to awake the patient, and/or the programming of a medical device implanted in the patient. Further, in some cases, the detected aberrant behavior and/or events surrounding the aberrant behavior can be transmitted from the bedside monitor to a remote monitor. Information can be retrieved from the remote monitor by a clinician and used in real time, or at a later time to diagnose and/or treat the patient.
Description
- This patent application is a divisional of U.S. patent application Ser. No. 10/837,851 filed on May 3, 2004, which is a continuation-in-part of U.S. Ser. No. 10/793,177 filed on Mar. 4, 2004, now abandoned, to which priority is claimed under 35 U.S.C. §120, and which are incorporated herein by reference in their entireties.
- The present invention is related to implantable medical devices, and in particular to a cardiac arrest and/or sleep apnea monitoring devices capable of detecting aberrant behavior and/or implementing corrective action in relation to a detected aberrant behavior.
- A large number of people suffer from obesity and/or heart disease. In these people, it is common to find heightened respiratory discomfort and shortness of breath during periods of sleep. In addition, these people often experience breathing characterized by rhythmic waxing and waning of the depth of respiration with regularly recurring periods of apnea, clinically described as Cheyne-stokes breathing.
- In general, there are two kinds of sleep related apnea that are associated with heart disease. First, central sleep apnea is the most common type found and is probably caused by heart failure. This type of apnea may be developed after a heart attack and is usually a contributing factor to heart failure. During central sleep apnea, patients stop breathing and begin to suffocate causing them to wake-up. The awakening jolts their heart muscles into action when they should be resting and thus the jolting action puts stress on the heart.
- The other type of sleep related apnea is obstructive sleep apnea and may contribute to heart failure. Obstructive sleep apnea is commonly found in people with oversized necks. Such people are typically overweight and suffer from snoring. Muscle tone keeps the throat open during the day, but at night the weight of the oversized neck narrows the airway. As a result, the tongue falls back closing the airway. The person struggles to breathe against the collapsed throat as if choking. This breathing effort can put an additional strain on the heart.
- Excessive pressure on the heart can be created during periods of apnea. These excessive pressures can be particularly problematic for patients already suffering from heart disease. In some cases, these excessive pressures can cause heart attack and/or death. Accordingly, for at least the aforementioned reasons, there exists a need in the art for advanced respiratory and/or heart function detection, and/or systems and methods for intervention where aberrant behavior is detected.
- The present invention provides various systems and methods for intervening where aberrant heart, respiratory, and/or other dysfunction is detected. For example, some embodiments of the present invention provide a monitor capable of detecting the occurrence of sleep apnea, and for audibly alerting the patient (o a spouse or caregiver associated with the patient) in which the sleep apnea is detected. In some cases, a pacemaker or some other medical device detects an abnormality indicative of the sleep apnea. An information signal indicating the detected aberrant condition is transmitted from the pacemaker to a bedside monitor. Based in the received information signal, the bedside monitor can sound an audible alarm to awake the patient. Further, in some cases, an electrocardiogram (EGM) and/or other physical signals sensed by the pacemaker can be transmitted from the bedside monitor to a remote monitor. Information can be retrieved from the remote monitor by a clinician and used in real time, or at a later time to diagnose and/or treat the patient. Further, in some cases, the remote monitor can dispatch emergency medical personnel to the location indicated by the bedside monitor. Because of the patient information provided to the remote monitor, the emergency medical personnel can arrive at the patient's location prepared to intervene.
- Various embodiments of the present invention provide systems for detecting aberrant behavior of a living being. Examples of such aberrant behavior includes, but is not limited to, a lack of heart functionality, a low heart rate, a high heart rate, a sleep apnea, an atrial fibrillation, a ventricular fibrillation, a shallow breathing, a lack of breathing, and/or the like. Such systems include, a receiver capable of receiving an information signal from a deployed, implantable medical device. The information signal is received via a wireless transmission from the medical device, and thus, the receiver is disposed within a telemetry range associated with the deployed, implantable medical device. In some cases, this telemetry ranges is very limited, and thus the receiver includes a sensor, such as, for example, a thin, small adhesive backed receiver to be applied to the skin of a patient in which the implantable medical device is deployed. In other cases, the telemetry range is significant allowing for reception of the information signal at a distance of several feet or more from the deployed, implantable medical device.
- The systems further include a processor that is capable of associating a time stamp with the information signal received from the deployed, implantable medical device. In some cases, additional information can also be associated with the information signal such as, for example, a physical location of the processor. This information can be transmitted along with the time stamp and diagnostic information from the information signal to a remote monitor via a communication system. The remote monitor can use the transmitted information for immediate or later diagnosis and treatment, and/or for dispatching emergency medical assistance.
- The systems also include a therapy delivery system that is operable to initiate a therapy based at least in part on the information signal from the deployed, implantable medical device. In one particular case, the information signal from the deployed, implantable medical device indicates an occurrence of sleep apnea, and the therapy delivery system includes a speaker that is operable to emit an audible noise upon the occurrence of sleep apnea. In another case, the information signal from the deployed, implantable medical device indicates an occurrence of a particular aberrant, and the therapy delivery system includes a programmer operable to transfer programming parameters to the implantable medical device in response to the particular aberrant behavior.
- In various instances, the systems further include a diagnostic system that is operable to determine an aberrant behavior based at least in part on the information signal from the deployed, implantable medical device. In other instances, the deployed, implantable medical device includes a diagnostic system operable to identify an aberrant behavior, and the information signal from the deployed, implantable medical device indicates the aberrant behavior. In yet other instances, both the deployed, implantable medical device and the system include diagnostic systems that can each perform all or a portion of diagnosing aberrant behavior.
- Other embodiments of the present invention provide systems for indicating an irregular physical condition. Such systems include a local monitor and a programmer disposed at a first distance to a deployed, implantable medical device. As an example, where the deployed, implantable medical device utilizes inductive telemetry, a receiver could be a standalone telemetry/alarm which is applied to the skin of the living being near the deployed, implantable medical device. Alternatively, where a stronger transmitter allows for an increased telemetry range, the receiver can be included in a monitor placed some distance from the living being. The local monitor includes a diagnostic system and an alert system. In addition, the systems include a remote monitor disposed at a second distance to the deployed, implantable medical device. The remote monitor is communicably coupled to the local monitor.
- In some cases, the programmer is communicably coupled to the local monitor and is operable to initiate a therapy based at least in part on an output from the diagnostic system operating on information received from the deployed, implantable medical device. In particular cases, the diagnostic system is operable to detect sleep apnea, and when sleep apnea is detected, a speaker associated with the alert system sounds an audible alarm. The speaker can be located remote or local to the patient in which the implantable device is employed. Thus, for example, the speaker can sound an audible alarm local to the patient such that the patient is woken, or the speaker can be in a caregiver's room next to the patient's room. Sounding the audible alarm awakens the caregiver who in turn can alert the patient.
- In various cases, the system further includes a communication device that is operable to provide communication between the local monitor and the remote monitor. This communication device can be one of a number of device types including, but not limited to, an analog modem, or a digital based communication device.
- Yet other embodiments of the present invention provide systems for mitigating an irregular physical condition. The systems include a local monitor disposed within a telemetry range of a deployed, implantable medical device. The local monitor includes a processor that is communicably coupled to a computer readable medium. The computer readable medium includes instructions executable by the processor to receive an information signal from the deployed, implantable medical device; associate a time stamp with the information signal from the deployed, implantable medical device; initiate a therapy based at least in part on the information signal from the deployed, implantable medical device; and communicate a message to a remote monitor based at least in part on the information signal from the deployed, implantable medical device and the time stamp.
- Yet further embodiments of the present invention provide methods for mitigating an irregular physical condition. The methods include receiving an information signal from a deployed, implantable medical device at a local monitor. The information signal is stored and associated with a time stamp. Based at least in part on the information signal from the deployed, implantable medical device, a therapy is initiated. Further, the methods include communicating a message based at least in part on the information signal and the time stamp to a remote monitor disposed beyond the telemetry range of the deployed, implantable medical device. In some cases, communication between the local monitor and the remote monitor is performed over a wired and/or wireless transmission medium including, but not limited to, a cellular telephone link, the Internet, a virtual private network, a public switched telephone network, and/or combinations thereof.
- In some cases, the therapy includes sounding an external alarm designed to awaken a sleeping patient or to alert a caregiver, while in other cases, the therapy involves modifying the functionality of the deployed, implanted medical device. Modifying the functionality of the deployed, implantable medical device can include, but is not limited to, delivering a shock from an implanted pacemaker and/or speeding heart rate parameters controlled by the pacemaker.
- This summary provides only a general outline of some embodiments of the present invention. Many other objects, features, advantages and other embodiments of the present invention will become more fully apparent from the following detailed description, the appended claims and the accompanying drawings.
- A further understanding of the various embodiments of the present invention may be realized by reference to the figures which are described in remaining portions of the specification. In the figures, like reference numerals are used throughout several to refer to similar components. In some instances, a sub-label consisting of a lower case letter is associated with a reference numeral to denote one of multiple similar components. When reference is made to a reference numeral without specification to an existing sub-label, it is intended to refer to all such multiple similar components.
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FIG. 1 depicts an exemplary implantable medical device that can be used in relation to embodiments of the present invention; -
FIG. 2 illustrates a system in accordance with various embodiments of the present invention; -
FIG. 3 are flow diagrams that illustrate system operation in accordance with some embodiments of the present invention; -
FIG. 4 is a flow diagram illustrating a method in accordance with various embodiments of the present invention for detecting and intervening in sustained hyperventilation; -
FIG. 5 is a flow diagram depicting a method in accordance with some embodiments of the present invention for detecting and intervening in bradycardia; -
FIG. 6 is a flow diagram illustrating a method in accordance with some embodiments of the present invention for detecting and intervening in pacing minimum threshold; and -
FIG. 7 is a flow diagram illustrating a method in accordance with some embodiments of the present invention for detecting atrial tachycardia and intervening therein. - The present invention provides various systems and methods for intervening where aberrant behavior of a living being is detected. The aberrant behavior can include, but is not limited to, a malfunction of the heart or shallow breathing. As one particular example, some embodiments of the present invention provide a monitor capable of detecting the occurrence of sleep apnea, and for audibly alerting the patient in which the sleep apnea is detected or a spouse of the patient. In some cases, a pacemaker or some other medical device detects an abnormality indicative of the sleep apnea, and an information signal indicating the detected condition is transmitted from the pacemaker to a bedside monitor. In addition, the information can be communicated from the local monitor to a remote monitor. The remote monitor can be accessed by a clinician and used in real time, or at a later time to diagnose and/or treat the patient. Further, in some cases, the remote monitor can dispatch emergency medical personnel to the location indicated by the bedside monitor. Because of the patient information provided to the remote monitor, the emergency medical personnel can arrive at the patient's location prepared to intervene.
- As used herein, the terms “aberrant behavior” and “irregular physical condition” are is used in the broadest sense, and can include any function of a living being or devices implanted in the living being that is outside an established range. Thus, as just some examples, aberrant behavior can include a sleep apnea, an atrial fibrillation, a ventricular fibrillation, a shallow breathing, a lack of breathing, a lack of heart functionality, a low heart rate, a high heart rate, and/or a malfunction of a deployed, implantable medical device. Also, as used herein the term “deployed, implantable medical device” is used in its broadest sense and can be any device deployed either internal to or integrally attached to a living being. These devices are typically capable of monitoring, controlling, and/or intervening in the functionality of the living being. As just one example, a deployed, implantable medical device can be a pacemaker capable of delivering stimuli to a heart, and monitoring various life functions associated with the living being. Such deployed, implantable medical devices can include one or more of a plethora of sensors known in the art that are able to detect patient conditions including, but not limited to, an evoked response sensor to detect ventricular or atrial fibrillation, a minute ventilation sensor to detect breathing or a lack thereof, sense amplifiers to detect a beating heart in the atrium and ventricle, and/or the like. As used herein, a living being can be a human, or another animal.
- Turning to
FIG. 1 , an exemplary implantablemedical device 100 is depicted in relation to ahuman heart 110. As illustrated, implantablemedical device 100 is a cardiac rhythm device, but as previously stated, can be any type of implantable medical device as that term is understood in its broadest sense. The illustrated device is more fully described in U.S. Pat. No. 5,974,340 which is incorporated herein in its entirety for all purposes. In this case, implantablemedical device 100 is operatively connected to a patient'sheart 110 by electrical conductors embodied in apacing lead 120. Ahousing 130 of the implantable medical is implanted in a surgically made pocket, typically in either the left or right pectoral region of the patient. Implantablemedical device 100 includes microprocessor-base controller 194 that is programmed to operate in a plurality of modes, well known to those skilled in the art. Microprocessor basedcontroller 194 has a RAM (random access memory) 190 and a ROM (read only memory) 188 for storing programs and data. Microprocessor basedcontroller 194 controls the delivery of cardiac stimulation pulses by apulse generator 180 to simulatingelectrodes lead 120.Electrode 124 is connected to aventricular sense amplifier 166 andelectrode 125 is connected to theatrial sense amplifier 164. Theelectrodes digital converter controller 194 for evaluation and for determining cardiac stimulation. - As illustrated, an
accelerometer 184 is positioned withinhousing 130 of the cardiac rhythm management device and coupled to microprocessor-basedcontroller 194 via an analog todigital converter 178. By positioningaccelerometer 184 incasing 130,accelerometer 184 generates a global signal associated with the various atrial and ventricular events. Where implantablemedical device 100 is to be used to measure intracardiac impedance, anoscillator 162 is incorporated withincase 130 for applying a high frequency carrier betweenelectrodes metal case 130 andelectrode 124. - The analog signal output of
accelerometer 184 indicates events associated with the heart sounds, compressions, cardiac wall accelerations and decelerations caused by cardiac events along with motion artifacts and respiratory events. The signal is passed through alow pass filter 182. The resultant wave form can be associated with respiration or minute volume. The accelerometer signal is transmitted to an analog todigital converter 178 where it is digitized before being transmitted to the microprocessor-basedcontroller 194. At microprocessor-basedcontroller 194, the digitized signal is processed and analyzed. - Respiration may also be monitored from the intracardiac impedance measurements. As well known in the art,
oscillator 162 is used to provide a relatively high frequency, low amplitude alternating current for impedance measurement. A carrier frequency typically between 1 kHz and 100 kHz may be used. The respiratory or pulmonary and cardiac signals modulate the carrier and are readily separated from the high frequency carrier by ademodulator 172. The intracardiac impedance measurements are generally low-pass filtered 30 with afilter 174 to isolate the ventilation activity where amplitude is related to tidal volume. More particularly, this signal may be low-pass filtered at about a 2 Hz cut off frequency to isolate the ventilation activity component. - Programming parameters for operating implanted
medical device 100 can be received from a local external monitor/programmer 140 via awireless communication link 150. Further, an information signal from implantablemedical device 100 can be provided to local external monitor/programmer 140 viacommunication link 150. In particular, information (e.g., a number of parameters) can be organized by microprocessor-basedcontroller 194, passed to an input/output port 192, and then transmitted by atransceiver 186 to local external monitor/programmer 140. In the reverse, programming parameters can be 10 passed from local external monitor/programmer 140 totransceiver 150 viacommunication link 150. These parameters can then be passed via input/output port 192 and to microprocessor-basedcontroller 194. These parameters can be used to modify the operation of implantablemedical device 100. - As set forth in greater detail in U.S. Pat. No. 5,974,340, various implantable medical devices including, but not limited to, the device described in relation to
FIG. 1 measure activity and respiratory signals for the purposes of rate adaptive pacing. Respiration can be determined by minute ventilation which is the product of respiratory rate and tidal volume. Minute ventilation is estimated by frequent measurements of trans-thoracic impedance between an intracardiac lead and the pulse generator case using a bipolar system. Further details regarding trans-thoracic impedance can be found in U.S. Pat. No. 6,684,101. The entirety of the aforementioned patent is incorporated herein by reference for all purposes. A low energy pulse of known current amplitude, well below the threshold of stimulation, is delivered from the ring electrode of a standard bipolar pacing lead. The resultant voltage between the tip electrode and the pulse generator case is measured and the impedance is calculated. By measuring the frequency of respiration, related fluctuations in impedance (correlated with respiratory rate) and the amplitude of those excursions (correlated with tidal volume) minute ventilation can be estimated. The respiratory information derived from the impedance waveform can be used as a physiological functional parameter for determining optimum pacing rate in a rate responsive pacer or can be used to monitor respiratory activity. - The trans-thoracic impedance signal is a complex parameter influenced by several factors. However, the trans-thoracic impedance is most closely related to the volume and resistivity of the blood in the heart and the systemic venous system. The impedance signal fluctuates in response to both respiration and cardiac motion (ventricular ejection). This information can be quantified and passed from deployed, implantable
medical device 100 to local external monitor/programmer 140 viacommunication link 150. - Turning to
FIG. 2 , asystem 200 in accordance with various embodiments of the present invention is illustrated.System 200 includes local external monitor/programmer 240 communicably coupled to aremote monitor 250 via acommunication network 270. Local external monitor/programmer 240 includes anantenna 246 that provides for communication with a deployed, implantablemedical device 110 disposed within a living being 210. Local external monitor/programmer 240 further includes aspeaker 249 capable of emitting an audible signal, and adisplay 248 capable of providing one or more messages related the operation of deployed, implantablemedical device 110. Further, local external monitor/programmer 240 includes one ormore input mechanisms -
Communication network 270 can be any communication network including, but not limited to, the Internet, a virtual private network, a local area network, a pager network, a cellular telephone network, a public switched telephone network, a direct wired connection, combinations of the aforementioned, and/or the like.Remote monitor 250 is communicably coupled to adatabase 252. As used herein, the term “communicably coupled” is to be interpreted in its broadest sense, and indicates any coupling whereby information can be passed from a source to a destination. Thus, two devices can be communicably coupled where they communicate via a wire, or where they communicate wirelessly.System 200 also includes aremote access station 266 comprised of acomputer 260, monitor 262 andinput device 264.Remote access station 266 is communicably coupled toremote monitor 250 and/or local external monitor/programmer 140, and can access and utilize information maintained ondatabase 252. - In operation, an information signal is passed from deployed, implantable
medical device 110 viacommunication link 150 to local external monitor/programmer. In some cases, the information signal indicates one or more aberrant behaviors detected in relation to living being 210 and/or deployed, implantablemedical device 110. Upon receiving this information signal, local external monitor/programmer 140 can perform one of a number of functions. Local external monitor/programmer 140 can associate a time stamp with the received information signal and store both the time stamp and the received information signal. In some embodiments, the deployed, implantable medical device associates a time stamp with the episode information. In various cases, the information signal passed from the deployed, implantable medical device includes one or more event counters and stored electrograms. Such event counters can include an indication of the number of incidents of sleep apnea detected, and/or the like. - In addition, local external monitor/
programmer 140 can apply diagnostic tests to the received information and select one or more therapies to be provided. For example, where sleep apnea is indicated, an audible alarm can be sounded viaspeaker 249 in an attempt to awaken living being 210. Alternatively, or in addition, an audible alarm can be sounded via aspeaker 290 located remote from living being 210. The remote location can be, for example, near a caregiver who in turn can attempt to awaken living being 210 and/or provide additional care. For example, the caregiver could apply external defibrillation where an unconverted tachycardia is detected, or could apply a some shock event when living being 210 is unconscious or vulnerable. - Further, diagnostic tests run by one or both of local external monitor/
programmer 140 and deployed, implantablemedical device 110 may indicate initiation of a therapy using deployed, implantablemedical device 110 to deliver that therapy. In such a case, deployed, implantablemedical device 110 may initiate the therapy on its own. - Alternatively, local external monitor/
programmer 140 can upload operational parameters viacommunication link 150 to deployed, implantablemedical device 110 directed at initiating the therapy. In turn, deployed, implantable medical device can implement the received operational parameters directed at alleviating or curing the detected aberrant behavior. Thus, for example, where sleep apnea is detected, parameters to speed the heart rate may be uploaded to deployed, implantable medical device. Alternatively, where some form of arrhythmia is detected, parameters causing a shock to be delivered to the heart may be uploaded to deployed, implantable medical device. Based on the disclosure provided herein, one of ordinary skill in the art will recognize a number of possible therapies that can be implemented in relation to living being 210 and/or deployed, implantablemedical device 110. - In addition, local external monitor/
programmer 140 can upload incident information toremote monitor 250 viacommunication network 270. This incident information can include the information signal received from deployed, implantablemedical device 110, and a time stamp applied by local external monitor/programmer 140. In addition, any diagnostics performed by local external monitor/programmer 140, parameter changes performed by local external monitor/programmer 140, and/or the physical location of local external monitor/programmer 140 can be uploaded toremote monitor 250. - This incident information can then be accessed via one or more
remote access stations 266. Thus, for example, where the patient is suffering from sleep apnea, the patient's physician may use aremote access station 266 to evaluate the progress of the patient. This can be done in real time, or later during, for example, the patient's next scheduled appointment with the physician. Where monitoring is ongoing in real time, the physician may enter programming commands that cause local external monitor/programmer 140 to implement a particular therapy specified by the physician. As previously discussed, the therapy can be external in the form of an audible alarm and/or internal in the form of a modification of the parameters of deployed, implantablemedical device 110. - In one particular case,
remote access station 266 is located in a physician's office, while in other cases,remote access station 266 is located in an emergency dispatch office or in an ambulance. Thus, in some cases,remote access station 266 can be used to alert emergency medical personnel about an ongoing aberration, and dispatch the personnel to the patient's location based on the location information provided by local external monitor/programmer 140. Based on the disclosure provided herein, one of ordinary skill in the art will recognize a number of other locations that would be benefited by a remote access station. - Turning to
FIG. 3 , a flow diagram 300 describing a method in accordance with various embodiments of the present invention is discussed. Following flow diagram 300, internal activity of a living being is monitored via a deployed, implantable medical device (block 302). This monitoring includes detection of one or more aberrant behaviors. Thus, for example it is determined whether a cardiac arrest is detected (block 304). Where a cardiac arrest is not detected (block 304), it is determined if the patient is in a restive state (block 306), where the patient may be exposed to the occurrence of sleep apnea. Where the patient is in a restive state, it is determined if the patient's respiration indicates the onset of sleep apnea (block 308). Where either the patient is not resting (block 306) or that respiration is normal (block 308), the monitoring is continued (block 302). It will be appreciated that the aberrant behaviors used in flow diagram 300 (blocks 304, 308) are merely exemplary and that a myriad of other behaviors can be detected in addition to or in place of those described. - Where a cardiac arrest is detected (block 304) or where abnormal respiration is detected (block 308), a number of parameters monitored by deployed, implantable
medical device 110 are prepared for transfer (block 310). In some cases, deployed, implantablemedical device 110 can monitor several hundred or more parameters. With the information prepared for transfer (block 310), it is transmitted to local external monitor/programmer 140 (block 312). In one particular case, the information signal transmitted is a binary encoded signal. - Turning to
FIG. 3 b, the transmitted information is received by local external monitor/programmer 140 (block 314). It is determined if the indicated aberrant behavior can be mitigated locally (block 316). If local mitigation is possible (block 316), a mitigation strategy or therapy is selected based on a diagnostic system implemented as part of local external monitor/programmer 140 (block 318). It is determined if the selected therapy requires programming of deployed, implantable medical device 110 (block 320). Where programming is called for (block 320), operational parameters associated with the therapy are selected and uploaded from local external monitor/programmer 140 to deployed, implantable medical device 110 (block 322). Further, it is determined if a local external strategy or therapy is called for (block 324). Where such an external therapy is called for (block 324), the external therapy is implemented (block 326). - In addition, the information from local external monitor/
programmer 140 is transmitted to remote monitor 250 (block 328). Turning toFIG. 3 c,remote monitor 250 receives the information transmitted from local external monitor/programmer 140 (block 330). It is determined if the information transmitted requires immediate attention, or if it can merely be recorded for later consideration (block 332). Where the information indicates the need for immediate attention (block 332), a party to be alerted is identified (block 334) and the party is alerted (block 336). This can include, but is not limited to, emergency medical personnel. Thus, for example, a message including the information from localexternal programmer 140 can be transferred to an ambulance station, and the ambulance can be dispatched to the location of the localexternal programmer 140. Alternatively, or in addition, the information can be transferred to an emergency room that can thus be prepared to receive the patient transported in the ambulance. Based on the disclosure provided herein, one of ordinary skill in the art will recognize a number of other parties that can be alerted in accordance with various embodiments of the present invention. - In addition, the information from local
external programmer 140 is stored to a database communicably coupled to remote monitor 250 (block 338). This information can be accessed at a later time by, for example, a physician or other medical personnel and used to treat and/or diagnose the patient. - Turning to
FIG. 4 , a flow diagram 400 illustrates a method in accordance with various embodiments of the present invention for detecting and intervening in sustained hyperventilation. Following flow diagram 400, activity monitoring is performed by a pacemaker (PG) (block 405). A sustained hyperventilation condition is indicated when a resting state of the patient under monitor (block 410) along with a high breathing rate (block 415) are detected. Such a high breathing rate can be, for example, detected using minute ventilation transthorasic impedance monitoring over time. Where it is determined that the patient is involved in some level of physical activity that justifies a higher breathing rate, then the high breathing rate is considered normal and no notification is provided. Alternatively, where it is determined that the patient is in a resting or sedentary state and a sustained high breathing rate is observed, sustained hyperventilation is indicated (blocks 410, 415), and the detected condition is communicated by the PG to the bedside monitor (block 420). The bedside monitor queries the PG to determine if the PG is modifying the atrial or ventricular pacing rate based on the breathing rate (i.e., the PG MV rate responsive) (block 425). If it is determined that the PG is responsive to the breathing rate (block 425), the bedside monitor programs the PG with updated parameters (block 430) that cause the PG to discontinue pacing modification with respect to the breathing rate. The pacing rate would then typically 30 drop to a more appropriate rate that is not influenced by the high breathing rate. At this point, the event is logged (block 435) and communicated to a remote monitor (block 440). Alternatively, where the PG is not breathing rate responsive (block 425) the event is logged (block 435) and communicated to a remote monitor (block 440). - Turning to
FIG. 5 , a flow diagram 500 depicts a method in accordance with some embodiments of the present invention for detecting and intervening in untreated bradycardia. Untreated bradycardia occurs when a patient's intrinsic heart rate is allowed to drop to less than forty to fifty beats per minute. Such a low heart rate can result in fainting or other indications of stress. It is untreated where the PG does not automatically mitigate this occurrence. Following flow diagram 500, activity monitoring is performed by a PG (block 505). Where the PG detects an untreated bradycardia (block 510), an alarm or SOS signal is communicated to a bedside monitor indicating the detected low pacing rate (block 515). The bedside monitor sounds a local alarm (block 520), and the condition as well as events surrounding the condition are logged (block 525). In addition, the bedside monitor queries the PG to determine if the PG can be reprogrammed to address the detected condition (block 530). Thus, for example, it can be determined if a rate drop feature in the PG is enabled which is allowing the detected condition to occur. As other examples, it can be determined if the lower rate limit on the PG device is simply programmed too low, or if there are other rate modifying features enabled that are allowing the rate to drop too low. If it is determined that the PG can be reprogrammed to alleviate the detected condition (block 530), the proposed therapy (e.g., reprogramming) is logged (block 535) and a program implementing the therapy in the PG is loaded to the PG (block 540). Thus, for example, if it is determined that a rate drop feature in the PG is enabled and potentially causing the condition, the feature can be disabled. Alternatively, or in addition, where it is determined that the minimum rate is programmed too low, it can be adjusted to a higher rate. Where neither of the aforementioned situations exist, the monitor can further evaluate if there are other pacing rate modifiers that are causing the detected condition. If so, these modifiers can be disabled. The detected condition and events detected in relation to the condition are communicated to the remote monitor (as well as any reprogramming of the PG) (block 545). - Turning to
FIG. 6 , a flow diagram 600 depicts a method in accordance with some embodiments of the present invention for detecting and intervening pacemaker mediated tachycardia (PMT). Following flow diagram 600, activity monitoring is performed by a PG (block 605). Where the PG detects PMT (block 610), it is determined if the PG includes PMT mitigation capability (block 615). Where such capability is found (block 615), it is determined if the capability is enabled and properly mitigating the PMT (block 620). Where the capability is not enabled or not properly mitigating the PMT (block 625), the PG is programmed to enable the capability (block 625). Alternatively, where the mitigation capability is enabled and properly mitigating PMT (block 620), the events surrounding the detection of the PMT as well as the mitigation efforts are logged (block 630) and communicated to a remote monitor (block 635). - Alternatively, where it is determined that the PO does not include PMT mitigation capability (block 615), the bedside monitor determines one or more parameters to be programmed into the PO allowing for mitigation of the detected condition, and the parameters are programmed to the PO (block 640). It is determined whether the detected PMT has been mitigated (block 645), and if it has not, additional PO parameters are selected (block 650) and programmed into the PO (block 640). This process can continue until mitigation of the PMT is complete or until some defined point. Where it is determined that the PMT has been mitigated (block 645), the events surrounding the detection of the PMT as well as the mitigation efforts are logged (block 630) and communicated to a remote monitor (block 635).
- Turning to
FIG. 7 , a flow diagram 700 illustrates a method in accordance with some embodiments of the present invention for detecting atrial tachycardia and intervening therein. Atrial tachycardia results in high ventricular pacing rate as the ventricle is paced in an effort to track runaway atrial events. Following flow diagram 700, activity monitoring is performed by a PO (block 705). Where the PO detects a sustained atrial tachycardia (block 710), an alarm or SOS signal is communicated to a bedside monitor (block 715). In addition, the monitor queries the PG to determine if ATR fallback is available (block 720). As may be appreciated by one of ordinary skill in the art, ATR fallback is a device feature that disassociates the device from the atrium so that pacing of the ventricle is based on something other than detection of the atrial signal. Such a feature can be used to prevent pacing the ventricle at the maximum rate during atrial tachycardia. Where ATR fallback is available (block 720), it is determined if it is enabled (block 725). Where ATR fallback is not enabled (block 725), it is changed by programming the PO to enable ATR fallback (block 730), and events surrounding the detected atrial fibrillation are logged (block 735) and communicated to a remote monitor (block 740). - Alternatively, where it is determined that ATR fallback is not available (block 720), the operational mode of the PG is changed to a non-atrial tracking mode (block 745). As may be appreciated by one of ordinary skill in the art, the non-atrial tracking mode is initiated by programming the PG to dissociate ventricular and atrial pacing, and thus allow the ventricular pacing rate to return to a more appropriate level. In addition, events surrounding the detected atrial fibrillation are logged (block 735) and communicated to a remote monitor (block 740).
- The invention has now been described in detail for purposes of clarity and understanding. However, it will be appreciated that certain changes and modifications may be practiced within the scope of the appended claims. Thus, although the invention is described with reference to specific embodiments and figures thereof, the embodiments and figures are merely illustrative, and not limiting of the invention. Rather, the scope of the invention is to be determined solely by the appended claims.
Claims (26)
1. A system for mitigating sleep disordered breathing, the system comprising:
an implantable sensor configured to determine if a patient is in a restive state;
an implantable medical device communicatively coupled to the sensor and configured to generate an information signal indicating an occurrence of apnea based at least in part on the restive state determination; and
a local external monitor comprising:
communication circuitry configured to receive the information signal;
memory configured to store the information signal; and
a processor configured to associate a time stamp with the information signal;
the processor configured to autonomously select and initiate at least one appropriate therapy from among a plurality of available therapies for mitigating the occurrence of the apnea based at least in part on the information signal; and
the processor cooperating with the communication circuitry to communicate a message based at least in part on the information signal and the time stamp to a remote monitor disposed beyond a telemetry range of the implantable medical device.
2. The system of claim 1 , wherein the information signal generated by the implantable medical device is received by the communication circuitry of the local monitor via a wireless link.
3. The system of claim 1 , wherein:
the local monitor is disposed within an external telemetry range of the implantable medical device deployed within the patient; and
the remote monitor is disposed beyond the external telemetry range.
4. The system of claim 1 , wherein the communication circuitry of the local monitor is configured to communicate the message to the remote monitor via a medium selected from a group consisting of a cellular telephone link, the Internet, a virtual private network, a public switched telephone network, a local area network, a pager network, and a direct wired connection.
5. The system of claim 1 , wherein the therapy includes sounding an audible alarm.
6. The system of claim 1 , wherein the processor is configured to initiate the therapy at least in part by programming the implantable medical device.
7. The system of claim 1 , wherein the processor is configured to associate the time stamp and a physical location of the processor with the information signal.
8. A programmer comprising at least the local monitor according to claim 1 .
9. A system for mitigating sleep disordered breathing, the system comprising:
an implantable sensor configured to determine if a patient is in a restive state;
an implantable medical device communicatively coupled to the sensor and configured to generate an information signal comprising sleep disordered breathing information based at least in part on the restive state determination;
a local external monitor comprising:
communication circuitry configured to receive the information signal;
memory configured to store the information signal;
an alert system comprising an alert generator configured to generate a perceivable alarm; and
a processor configured to associate a time stamp with the information signal; and
a diagnostic system configured to indicate an occurrence of apnea based at least in part on the information signal;
the processor configured to autonomously select and initiate at least one appropriate therapy from among a plurality of available therapies for mitigating the occurrence of the apnea based at least in part on the information signal; and
the processor cooperating with the alert system to communicate a message based at least in part on the information signal and the time stamp to a remote monitor disposed beyond a telemetry range of the implantable medical device.
10. The system of claim 9 , wherein the implantable medical device comprises the diagnostic system.
11. The system of claim 9 , wherein the local monitor comprises the diagnostic system.
12. The system of claim 9 , wherein the information signal generated by the implantable medical device is received by the communication circuitry of the local monitor via a wireless link.
13. The system of claim 9 , wherein:
the local monitor is disposed within an external telemetry range of the implantable medical device deployed within the patient; and
the remote monitor is disposed beyond the external telemetry range.
14. The system of claim 9 , wherein the communication circuitry of the local monitor is configured to communicate the message to the remote monitor via a medium selected from a group consisting of a cellular telephone link, the Internet, a virtual private network, a public switched telephone network, a local area network, a pager network, and a direct wired connection.
15. The system of claim 9 , wherein the therapy includes sounding an audible alarm generated by the alert system.
16. The system of claim 9 , wherein the processor is configured to initiate the therapy at least in part by programming the implantable medical device.
17. The system of claim 9 , wherein the processor is configured to associate the time stamp and a physical location of the processor with the information signal.
18. The system of claim 9 , wherein at least the communication circuitry, memory, alert system, and processor are disposed is a bedside monitor.
19. The system of claim 9 , wherein at least the communication circuitry, memory, and processor are disposed is a bedside monitor, and at least an output device of the alert system is disposed remotely of the beside monitor.
20. A system for mitigating sleep disordered breathing, the system comprising:
an implantable sensor arrangement configured to determine if a patient is in a restive state and to detect a breathing rate of the patient;
an implantable pulse generator coupled to the implantable sensor arrangement and configured to generate pacing pulses according to a pacing rate that is responsive to the detected breathing rate, the pulse generator configured to generate an information signal in response to concurrently determining that the patient is in the restive state and detecting a high breathing rate that exceeds a predetermined value; and
a local external monitor comprising:
communication circuitry configured to effect communication between the local monitor and the pulse generator, and to receive the information signal; and
a processor configured to query the pulse generator in response to the information signal to determine if the pulse generator is modifying the pacing rate based on the breathing rate; and
the processor configured to communicate with the pulse generator to cause a change in pulse generator operation such that the pacing rate is not responsive to the detected breathing rate.
21. The system of claim 20 , wherein the implantable sensor arrangement comprises a transthoracic impedance sensor.
22. The system of claim 20 , wherein the pulse generator is configured to generate the information signal indicating an occurrence of sustained hyperventilation in response to concurrently determining that the patient is in the restive state and detecting the high breathing rate that exceeds the predetermined value.
23. The system of claim 20 , wherein the pulse generator is configured to associate a time stamp with the information signal.
24. The system of claim 23 , wherein the communication circuitry of the local monitor is configured to communicate a message based at least in part on the information signal and the time stamp to a remote monitor disposed beyond a telemetry range of the pulse generator.
25. The system of claim 20 , wherein the processor is configured to communicate with the pulse generator to cause a reduction in the pacing rate to a rate that is not influenced by the high rate breathing.
26. The system of claim 20 , wherein the processor is configured to program the pulse generator with updated parameters that cause the pulse generator to discontinue pacing modification with response to the patient's breathing rate.
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Cited By (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8783250B2 (en) | 2011-02-27 | 2014-07-22 | Covidien Lp | Methods and systems for transitory ventilation support |
US9358355B2 (en) | 2013-03-11 | 2016-06-07 | Covidien Lp | Methods and systems for managing a patient move |
US9375542B2 (en) | 2012-11-08 | 2016-06-28 | Covidien Lp | Systems and methods for monitoring, managing, and/or preventing fatigue during ventilation |
US9993604B2 (en) | 2012-04-27 | 2018-06-12 | Covidien Lp | Methods and systems for an optimized proportional assist ventilation |
US10668239B2 (en) | 2017-11-14 | 2020-06-02 | Covidien Lp | Systems and methods for drive pressure spontaneous ventilation |
US11517691B2 (en) | 2018-09-07 | 2022-12-06 | Covidien Lp | Methods and systems for high pressure controlled ventilation |
US11666271B2 (en) | 2020-12-09 | 2023-06-06 | Medtronic, Inc. | Detection and monitoring of sleep apnea conditions |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US10129348B2 (en) | 2015-12-04 | 2018-11-13 | At&T Intellectual Property I, L.P. | Method and apparatus for modifying behavior of a user via a network |
Citations (88)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4648407A (en) * | 1985-07-08 | 1987-03-10 | Respitrace Corporation | Method for detecting and differentiating central and obstructive apneas in newborns |
US4860766A (en) * | 1983-11-18 | 1989-08-29 | Respitrace Corp. | Noninvasive method for measuring and monitoring intrapleural pressure in newborns |
US5101831A (en) * | 1989-07-07 | 1992-04-07 | Matsushita Electric Works, Ltd. | System for discriminating sleep state |
US5233983A (en) * | 1991-09-03 | 1993-08-10 | Medtronic, Inc. | Method and apparatus for apnea patient screening |
US5249572A (en) * | 1990-12-27 | 1993-10-05 | Ela Medical | Method and apparatus for controlling the pacing rate of a metabolic demand pacemaker |
US5275159A (en) * | 1991-03-22 | 1994-01-04 | Madaus Schwarzer Medizintechnik Gmbh & Co. Kg | Method and apparatus for diagnosis of sleep disorders |
US5353788A (en) * | 1992-09-21 | 1994-10-11 | Miles Laughton E | Cardio-respiratory control and monitoring system for determining CPAP pressure for apnea treatment |
US5485850A (en) * | 1993-08-13 | 1996-01-23 | Dietz; Henry G. | Monitor of low pressure intervals with control capabilities |
US5517983A (en) * | 1992-12-09 | 1996-05-21 | Puritan Bennett Corporation | Compliance meter for respiratory therapy |
US5738102A (en) * | 1994-03-31 | 1998-04-14 | Lemelson; Jerome H. | Patient monitoring system |
US5891180A (en) * | 1998-04-29 | 1999-04-06 | Medtronic Inc. | Interrogation of an implantable medical device using audible sound communication |
US5904708A (en) * | 1998-03-19 | 1999-05-18 | Medtronic, Inc. | System and method for deriving relative physiologic signals |
US5974340A (en) * | 1997-04-29 | 1999-10-26 | Cardiac Pacemakers, Inc. | Apparatus and method for monitoring respiratory function in heart failure patients to determine efficacy of therapy |
US6064910A (en) * | 1996-11-25 | 2000-05-16 | Pacesetter Ab | Respirator rate/respiration depth detector and device for monitoring respiratory activity employing same |
US6126611A (en) * | 1998-02-04 | 2000-10-03 | Medtronic, Inc. | Apparatus for management of sleep apnea |
US20010007053A1 (en) * | 1999-06-03 | 2001-07-05 | Bardy Gust H. | System and method for automated collection and analysis of patient information retreived from an implantable medical device for remote patient care |
US6299581B1 (en) * | 1992-05-07 | 2001-10-09 | New York University | Method and apparatus for optimizing the continuous positive airway pressure for treating obstructive sleep apnea |
US6304773B1 (en) * | 1998-05-21 | 2001-10-16 | Medtronic Physio-Control Manufacturing Corp. | Automatic detection and reporting of cardiac asystole |
US6306088B1 (en) * | 1998-10-03 | 2001-10-23 | Individual Monitoring Systems, Inc. | Ambulatory distributed recorders system for diagnosing medical disorders |
US20020002327A1 (en) * | 2000-04-10 | 2002-01-03 | Grant Brydon J.B. | Method for detecting cheyne-stokes respiration in patients with congestive heart failure |
US6336903B1 (en) * | 1999-11-16 | 2002-01-08 | Cardiac Intelligence Corp. | Automated collection and analysis patient care system and method for diagnosing and monitoring congestive heart failure and outcomes thereof |
US20020013613A1 (en) * | 1999-07-07 | 2002-01-31 | Markus Haller | System and method for remote programming of an implantable medical device |
US20020019606A1 (en) * | 2000-01-21 | 2002-02-14 | Lebel Ronald J. | Microprocessor controlled ambulatory medical apparatus with hand held communication device |
US20020019586A1 (en) * | 2000-06-16 | 2002-02-14 | Eric Teller | Apparatus for monitoring health, wellness and fitness |
US20020026223A1 (en) * | 1999-12-24 | 2002-02-28 | Riff Kenneth M. | Method and a system for using implanted medical device data for accessing therapies |
US20020029321A1 (en) * | 2000-08-21 | 2002-03-07 | Hidetaka Ebeshu | Cache system with limited number of tag memory accesses |
US6368284B1 (en) * | 1999-11-16 | 2002-04-09 | Cardiac Intelligence Corporation | Automated collection and analysis patient care system and method for diagnosing and monitoring myocardial ischemia and outcomes thereof |
US20020065539A1 (en) * | 2000-11-30 | 2002-05-30 | Von Arx Jeffrey A. | Telemetry apparatus and method for an implantable medical device |
US6398728B1 (en) * | 1999-11-16 | 2002-06-04 | Cardiac Intelligence Corporation | Automated collection and analysis patient care system and method for diagnosing and monitoring respiratory insufficiency and outcomes thereof |
US20020077673A1 (en) * | 2000-10-16 | 2002-06-20 | Remon Medical Technologies, Ltd. | Systems and methods for communicating with implantable devices |
US6411840B1 (en) * | 1999-11-16 | 2002-06-25 | Cardiac Intelligence Corporation | Automated collection and analysis patient care system and method for diagnosing and monitoring the outcomes of atrial fibrillation |
US20020082665A1 (en) * | 1999-07-07 | 2002-06-27 | Medtronic, Inc. | System and method of communicating between an implantable medical device and a remote computer system or health care provider |
US20020087203A1 (en) * | 2001-01-04 | 2002-07-04 | Steven Schmitt | System and method for receiving telemetry data from an implantable medical device |
US20020091416A1 (en) * | 2001-01-05 | 2002-07-11 | Wassmund Paul G. | Downloadable software support in a pacemaker |
US20020099424A1 (en) * | 2000-12-04 | 2002-07-25 | Bozidar Ferek-Petric | Implantable medical device telemetry control systems and methods of use |
US20020099412A1 (en) * | 1997-10-27 | 2002-07-25 | Neuropace, Inc. | Methods for using an implantable device for patient communication |
US20020103514A1 (en) * | 2001-01-31 | 2002-08-01 | St. Jude Medical Ab | Communication system and method for communicating between an implanted medical device and another device |
US20020111539A1 (en) * | 1999-04-16 | 2002-08-15 | Cosentino Daniel L. | Apparatus and method for two-way communication in a device for monitoring and communicating wellness parameters of ambulatory patients |
US6440066B1 (en) * | 1999-11-16 | 2002-08-27 | Cardiac Intelligence Corporation | Automated collection and analysis patient care system and method for ordering and prioritizing multiple health disorders to identify an index disorder |
US20020123673A1 (en) * | 1999-12-17 | 2002-09-05 | Webb James D. | Method and apparatus for remotely programming implantable medical devices |
US20020123776A1 (en) * | 2001-03-02 | 2002-09-05 | Von Arx Jeffrey A. | Antenna for an implantable medical device |
US20020123672A1 (en) * | 2000-10-26 | 2002-09-05 | Christophersom Mark A. | Externally worn transceiver for use with an implantable medical device |
US20020123036A1 (en) * | 2000-11-10 | 2002-09-05 | Francois Clavel | Method for analysing human immunodeficiency virus (HIV) phenotypic characteristics |
US20020147388A1 (en) * | 2001-04-06 | 2002-10-10 | Mass William R. | Passive telemetry system for implantable medical device |
US6466810B1 (en) * | 1995-11-22 | 2002-10-15 | Legacy Good Samaritan Hospital And Medical Center | Implantable device for monitoring changes in analyte concentration |
US20020151770A1 (en) * | 2001-01-04 | 2002-10-17 | Noll Austin F. | Implantable medical device with sensor |
US20020156504A1 (en) * | 2001-04-20 | 2002-10-24 | Chen Victor T. | Patient controlled atrial shock therapy |
US20030009204A1 (en) * | 2001-07-06 | 2003-01-09 | Amundson Mark D. | Adapative telemetry system and method for an implantable medical device |
US20030006898A1 (en) * | 2001-07-03 | 2003-01-09 | International Business Machines Corporation | Warning method and apparatus |
US20030022637A1 (en) * | 2001-07-26 | 2003-01-30 | Kabushiki Kaisha Toshiba | Electronic device and method of mounting radio antenna |
US20030023175A1 (en) * | 2001-05-22 | 2003-01-30 | Arzbaecher Robert C. | Implantable cardiac arrest monitor and alarm system |
US20030028226A1 (en) * | 1998-06-19 | 2003-02-06 | Medtronic, Inc. | Medical management system integrated programming apparatus for communication with an implantable medical device |
US20030025645A1 (en) * | 2001-08-03 | 2003-02-06 | Cardiac Pacemakers, Inc. | Circumferential antenna for an implantable medical device |
US20030041866A1 (en) * | 1999-12-17 | 2003-03-06 | Medtronic, Inc. | Virtual remote monitor, alert, diagnostics and programming for implantable medical device systems |
US6574507B1 (en) * | 1998-07-06 | 2003-06-03 | Ela Medical S.A. | Active implantable medical device for treating sleep apnea syndrome by electrostimulation |
US6574511B2 (en) * | 2000-04-21 | 2003-06-03 | Medtronic, Inc. | Passive data collection system from a fleet of medical instruments and implantable devices |
US20030114897A1 (en) * | 2001-12-19 | 2003-06-19 | Von Arx Jeffrey A. | Implantable medical device with two or more telemetry systems |
US20030114896A1 (en) * | 2001-12-19 | 2003-06-19 | Wim Boute | System and method for transmission of medical and like data from a patient to a dedicated internet website |
US6587725B1 (en) * | 1998-07-27 | 2003-07-01 | Dominique Durand | Method and apparatus for closed-loop stimulation of the hypoglossal nerve in human patients to treat obstructive sleep apnea |
US20030122718A1 (en) * | 2001-12-27 | 2003-07-03 | Shyh-Tirng Fang | Dual-frequency planar antenna |
US20030139778A1 (en) * | 2002-01-22 | 2003-07-24 | Fischell Robert E. | Rapid response system for the detection and treatment of cardiac events |
US20030144718A1 (en) * | 2002-01-29 | 2003-07-31 | Zeijlemaker Volkert A. | Method and apparatus for shielding coating for MRI resistant electrode systems |
US6602201B1 (en) * | 2000-07-10 | 2003-08-05 | Cardiodynamics International Corporation | Apparatus and method for determining cardiac output in a living subject |
US20030149423A1 (en) * | 2002-02-04 | 2003-08-07 | Fischell Robert E. | Methods for the detection and treatment of cardiac events |
US6609023B1 (en) * | 2002-09-20 | 2003-08-19 | Angel Medical Systems, Inc. | System for the detection of cardiac events |
US6622045B2 (en) * | 2001-03-29 | 2003-09-16 | Pacesetter, Inc. | System and method for remote programming of implantable cardiac stimulation devices |
US6622043B1 (en) * | 1999-06-25 | 2003-09-16 | Biotronik Mess- Und Therapiegeraete Gmbh & Co. Ingenieurbuero Berlin | Method of data interrogation in implant after-care |
US20030177031A1 (en) * | 2002-03-15 | 2003-09-18 | Medtronic, Inc. | Data management of patient medical information for use with an implantable medical device |
US20030195396A1 (en) * | 1998-09-30 | 2003-10-16 | Scarantino Charles W. | Methods, systems, and associated implantable devices for dynamic monitoring of physiological and biological properties of tumors |
US6636769B2 (en) * | 2000-12-18 | 2003-10-21 | Biosense, Inc. | Telemetric medical system and method |
US20030199945A1 (en) * | 2002-02-11 | 2003-10-23 | James Ciulla | Device and method for treating disordered breathing |
US6638231B2 (en) * | 2000-12-18 | 2003-10-28 | Biosense, Inc. | Implantable telemetric medical sensor and method |
US20030204216A1 (en) * | 2002-04-25 | 2003-10-30 | Ries Andrew J. | Electrically insulated component sub-assemblies of implantable medical devices |
US6752765B1 (en) * | 1999-12-01 | 2004-06-22 | Medtronic, Inc. | Method and apparatus for monitoring heart rate and abnormal respiration |
US20040122294A1 (en) * | 2002-12-18 | 2004-06-24 | John Hatlestad | Advanced patient management with environmental data |
US20040134496A1 (en) * | 2003-01-10 | 2004-07-15 | Cho Yong K. | Method and apparatus for detecting respiratory disturbances |
US20040138719A1 (en) * | 2003-01-10 | 2004-07-15 | Cho Yong K. | System and method for automatically monitoring and delivering therapy for sleep-related disordered breathing |
US20050061319A1 (en) * | 2003-09-18 | 2005-03-24 | Cardiac Pacemakers, Inc. | Methods and systems for implantably monitoring external breathing therapy |
US20050085865A1 (en) * | 2003-10-15 | 2005-04-21 | Tehrani Amir J. | Breathing disorder detection and therapy delivery device and method |
US20050113710A1 (en) * | 2003-09-18 | 2005-05-26 | Stahmann Jeffrey E. | Implantable device employing movement sensing for detecting sleep-related disorders |
US20060143372A1 (en) * | 2004-12-28 | 2006-06-29 | Walker Robert M | Directed auto-refresh synchronization |
US7094207B1 (en) * | 2004-03-02 | 2006-08-22 | Pacesetter, Inc. | System and method for diagnosing and tracking congestive heart failure based on the periodicity of cheyne-stokes respiration using an implantable medical device |
US7115097B2 (en) * | 2003-10-09 | 2006-10-03 | Johnson Joseph L | Positive airway pressure notification system for treatment of breathing disorders during sleep |
US7179229B1 (en) * | 2004-04-07 | 2007-02-20 | Pacesetter, Inc. | System and method for apnea detection using blood pressure detected via an implantable medical system |
US7225013B2 (en) * | 2003-05-15 | 2007-05-29 | Widemed Ltd. | Adaptive prediction of changes of physiological/pathological states using processing of biomedical signals |
US7225021B1 (en) * | 2004-01-30 | 2007-05-29 | Pacesetter, Inc. | Differentiation of central sleep apnea and obstructive sleep apnea using an implantable cardiac device |
US20070143741A1 (en) * | 2005-12-07 | 2007-06-21 | Microsoft Corporation | Efficient per-object operations in software transactional memory |
US20070239057A1 (en) * | 2006-03-29 | 2007-10-11 | Yanchuan Pu | Periodic disordered breathing detection |
Family Cites Families (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6644321B1 (en) | 1999-10-29 | 2003-11-11 | Medtronic, Inc. | Tactile feedback for indicating validity of communication link with an implantable medical device |
WO2001045793A1 (en) | 1999-12-21 | 2001-06-28 | Medtronic, Inc. | System for dynamic remote networking with implantable medical devices |
US6650944B2 (en) | 2000-02-23 | 2003-11-18 | Medtronic, Inc. | Follow-up monitoring method and system for implantable medical devices |
DE10008917A1 (en) | 2000-02-25 | 2001-08-30 | Biotronik Mess & Therapieg | Arrangement for monitoring and localizing patients |
WO2001097909A2 (en) | 2000-06-14 | 2001-12-27 | Medtronic, Inc. | Deep computing applications in medical device systems |
US6658300B2 (en) | 2000-12-18 | 2003-12-02 | Biosense, Inc. | Telemetric reader/charger device for medical sensor |
CA2431420C (en) | 2000-12-21 | 2011-10-11 | Insulet Corporation | Medical apparatus remote control and method |
US6650941B2 (en) | 2000-12-22 | 2003-11-18 | Medtronic, Inc. | Implantable medical device programming wands having integral input device |
US6873870B2 (en) | 2001-04-30 | 2005-03-29 | Medtronic, Inc. | Methods for adjusting cardiac detection criteria and implantable medical devices using same |
US6636762B2 (en) | 2001-04-30 | 2003-10-21 | Medtronic, Inc. | Method and system for monitoring heart failure using rate change dynamics |
US6910084B2 (en) | 2001-04-30 | 2005-06-21 | Medtronic, Inc | Method and system for transferring and storing data in a medical device with limited storage and memory |
US6686886B2 (en) | 2001-05-29 | 2004-02-03 | International Business Machines Corporation | Integrated antenna for laptop applications |
US6731984B2 (en) | 2001-06-07 | 2004-05-04 | Medtronic, Inc. | Method for providing a therapy to a patient involving modifying the therapy after detecting an onset of sleep in the patient, and implantable medical device embodying same |
US6648823B2 (en) | 2001-07-31 | 2003-11-18 | Medtronic, Inc. | Method and system of follow-up support for a medical device |
US6647299B2 (en) | 2001-09-21 | 2003-11-11 | Medtronic, Inc. | Patient programmer for implantable medical device with audio locator signal |
US6658283B1 (en) | 2001-09-25 | 2003-12-02 | Pacesetter, Inc. | Implantable cardiac stimulation device, system and method which provides an electrogram signal having the appearance of a surface electrocardiogram |
SE0201490D0 (en) | 2002-05-17 | 2002-05-17 | St Jude Medical | Implantable Antenna |
-
2004
- 2004-05-03 US US10/837,851 patent/US7751894B1/en not_active Expired - Fee Related
-
2010
- 2010-06-24 US US12/822,477 patent/US20100262032A1/en not_active Abandoned
Patent Citations (99)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4860766A (en) * | 1983-11-18 | 1989-08-29 | Respitrace Corp. | Noninvasive method for measuring and monitoring intrapleural pressure in newborns |
US4648407A (en) * | 1985-07-08 | 1987-03-10 | Respitrace Corporation | Method for detecting and differentiating central and obstructive apneas in newborns |
US5101831A (en) * | 1989-07-07 | 1992-04-07 | Matsushita Electric Works, Ltd. | System for discriminating sleep state |
US5249572A (en) * | 1990-12-27 | 1993-10-05 | Ela Medical | Method and apparatus for controlling the pacing rate of a metabolic demand pacemaker |
US5275159A (en) * | 1991-03-22 | 1994-01-04 | Madaus Schwarzer Medizintechnik Gmbh & Co. Kg | Method and apparatus for diagnosis of sleep disorders |
US5233983A (en) * | 1991-09-03 | 1993-08-10 | Medtronic, Inc. | Method and apparatus for apnea patient screening |
US6299581B1 (en) * | 1992-05-07 | 2001-10-09 | New York University | Method and apparatus for optimizing the continuous positive airway pressure for treating obstructive sleep apnea |
US5353788A (en) * | 1992-09-21 | 1994-10-11 | Miles Laughton E | Cardio-respiratory control and monitoring system for determining CPAP pressure for apnea treatment |
US5517983A (en) * | 1992-12-09 | 1996-05-21 | Puritan Bennett Corporation | Compliance meter for respiratory therapy |
US5715812A (en) * | 1992-12-09 | 1998-02-10 | Nellcor Puritan Bennett | Compliance meter for respiratory therapy |
US5485850A (en) * | 1993-08-13 | 1996-01-23 | Dietz; Henry G. | Monitor of low pressure intervals with control capabilities |
US5738102A (en) * | 1994-03-31 | 1998-04-14 | Lemelson; Jerome H. | Patient monitoring system |
US6466810B1 (en) * | 1995-11-22 | 2002-10-15 | Legacy Good Samaritan Hospital And Medical Center | Implantable device for monitoring changes in analyte concentration |
US6064910A (en) * | 1996-11-25 | 2000-05-16 | Pacesetter Ab | Respirator rate/respiration depth detector and device for monitoring respiratory activity employing same |
US5974340A (en) * | 1997-04-29 | 1999-10-26 | Cardiac Pacemakers, Inc. | Apparatus and method for monitoring respiratory function in heart failure patients to determine efficacy of therapy |
US20020099412A1 (en) * | 1997-10-27 | 2002-07-25 | Neuropace, Inc. | Methods for using an implantable device for patient communication |
US6126611A (en) * | 1998-02-04 | 2000-10-03 | Medtronic, Inc. | Apparatus for management of sleep apnea |
US5904708A (en) * | 1998-03-19 | 1999-05-18 | Medtronic, Inc. | System and method for deriving relative physiologic signals |
US5891180A (en) * | 1998-04-29 | 1999-04-06 | Medtronic Inc. | Interrogation of an implantable medical device using audible sound communication |
US6304773B1 (en) * | 1998-05-21 | 2001-10-16 | Medtronic Physio-Control Manufacturing Corp. | Automatic detection and reporting of cardiac asystole |
US20030028226A1 (en) * | 1998-06-19 | 2003-02-06 | Medtronic, Inc. | Medical management system integrated programming apparatus for communication with an implantable medical device |
US6574507B1 (en) * | 1998-07-06 | 2003-06-03 | Ela Medical S.A. | Active implantable medical device for treating sleep apnea syndrome by electrostimulation |
US6587725B1 (en) * | 1998-07-27 | 2003-07-01 | Dominique Durand | Method and apparatus for closed-loop stimulation of the hypoglossal nerve in human patients to treat obstructive sleep apnea |
US20030195396A1 (en) * | 1998-09-30 | 2003-10-16 | Scarantino Charles W. | Methods, systems, and associated implantable devices for dynamic monitoring of physiological and biological properties of tumors |
US6306088B1 (en) * | 1998-10-03 | 2001-10-23 | Individual Monitoring Systems, Inc. | Ambulatory distributed recorders system for diagnosing medical disorders |
US20020111539A1 (en) * | 1999-04-16 | 2002-08-15 | Cosentino Daniel L. | Apparatus and method for two-way communication in a device for monitoring and communicating wellness parameters of ambulatory patients |
US20010007053A1 (en) * | 1999-06-03 | 2001-07-05 | Bardy Gust H. | System and method for automated collection and analysis of patient information retreived from an implantable medical device for remote patient care |
US6622043B1 (en) * | 1999-06-25 | 2003-09-16 | Biotronik Mess- Und Therapiegeraete Gmbh & Co. Ingenieurbuero Berlin | Method of data interrogation in implant after-care |
US20020013613A1 (en) * | 1999-07-07 | 2002-01-31 | Markus Haller | System and method for remote programming of an implantable medical device |
US20020082665A1 (en) * | 1999-07-07 | 2002-06-27 | Medtronic, Inc. | System and method of communicating between an implantable medical device and a remote computer system or health care provider |
US6368284B1 (en) * | 1999-11-16 | 2002-04-09 | Cardiac Intelligence Corporation | Automated collection and analysis patient care system and method for diagnosing and monitoring myocardial ischemia and outcomes thereof |
US6398728B1 (en) * | 1999-11-16 | 2002-06-04 | Cardiac Intelligence Corporation | Automated collection and analysis patient care system and method for diagnosing and monitoring respiratory insufficiency and outcomes thereof |
US6411840B1 (en) * | 1999-11-16 | 2002-06-25 | Cardiac Intelligence Corporation | Automated collection and analysis patient care system and method for diagnosing and monitoring the outcomes of atrial fibrillation |
US6440066B1 (en) * | 1999-11-16 | 2002-08-27 | Cardiac Intelligence Corporation | Automated collection and analysis patient care system and method for ordering and prioritizing multiple health disorders to identify an index disorder |
US6336903B1 (en) * | 1999-11-16 | 2002-01-08 | Cardiac Intelligence Corp. | Automated collection and analysis patient care system and method for diagnosing and monitoring congestive heart failure and outcomes thereof |
US6752765B1 (en) * | 1999-12-01 | 2004-06-22 | Medtronic, Inc. | Method and apparatus for monitoring heart rate and abnormal respiration |
US20030041866A1 (en) * | 1999-12-17 | 2003-03-06 | Medtronic, Inc. | Virtual remote monitor, alert, diagnostics and programming for implantable medical device systems |
US20020123673A1 (en) * | 1999-12-17 | 2002-09-05 | Webb James D. | Method and apparatus for remotely programming implantable medical devices |
US20020026223A1 (en) * | 1999-12-24 | 2002-02-28 | Riff Kenneth M. | Method and a system for using implanted medical device data for accessing therapies |
US20020065454A1 (en) * | 2000-01-21 | 2002-05-30 | Lebel Ronald J. | Microprocessor controlled ambulatory medical apparatus with hand held communication device |
US20020065509A1 (en) * | 2000-01-21 | 2002-05-30 | Lebel Ronald J. | Microprocessor controlled ambulatory medical apparatus with hand held communication device |
US20030212441A1 (en) * | 2000-01-21 | 2003-11-13 | Medtronic Minimed, Inc. | Method and apparatus for communicating between an ambulatory medical device and a control device via telemetry using randomized data |
US20020019606A1 (en) * | 2000-01-21 | 2002-02-14 | Lebel Ronald J. | Microprocessor controlled ambulatory medical apparatus with hand held communication device |
US6635014B2 (en) * | 2000-01-21 | 2003-10-21 | Timothy J. Starkweather | Ambulatory medical apparatus and method having telemetry modifiable control software |
US20030176933A1 (en) * | 2000-01-21 | 2003-09-18 | Medtronic Minimed, Inc. | Microprocessor controlled ambulatory medical apparatus with hand held communication device |
US20020173830A1 (en) * | 2000-01-21 | 2002-11-21 | Starkweather Timothy J. | Method and apparatus for communicating between an ambulatory medical device and a control device via telemetry using randomized data |
US20020065540A1 (en) * | 2000-01-21 | 2002-05-30 | Lebel Ronald J. | Microprocessor controlled ambulatory medical apparatus with hand held communication device |
US20020002327A1 (en) * | 2000-04-10 | 2002-01-03 | Grant Brydon J.B. | Method for detecting cheyne-stokes respiration in patients with congestive heart failure |
US6574511B2 (en) * | 2000-04-21 | 2003-06-03 | Medtronic, Inc. | Passive data collection system from a fleet of medical instruments and implantable devices |
US20020019586A1 (en) * | 2000-06-16 | 2002-02-14 | Eric Teller | Apparatus for monitoring health, wellness and fitness |
US6602201B1 (en) * | 2000-07-10 | 2003-08-05 | Cardiodynamics International Corporation | Apparatus and method for determining cardiac output in a living subject |
US20020029321A1 (en) * | 2000-08-21 | 2002-03-07 | Hidetaka Ebeshu | Cache system with limited number of tag memory accesses |
US20020077673A1 (en) * | 2000-10-16 | 2002-06-20 | Remon Medical Technologies, Ltd. | Systems and methods for communicating with implantable devices |
US20020123672A1 (en) * | 2000-10-26 | 2002-09-05 | Christophersom Mark A. | Externally worn transceiver for use with an implantable medical device |
US20020123036A1 (en) * | 2000-11-10 | 2002-09-05 | Francois Clavel | Method for analysing human immunodeficiency virus (HIV) phenotypic characteristics |
US20030195589A1 (en) * | 2000-11-30 | 2003-10-16 | Cardiac Pacemakers, Inc. | Telemetry apparatus and method for an implantable medical device |
US20020065539A1 (en) * | 2000-11-30 | 2002-05-30 | Von Arx Jeffrey A. | Telemetry apparatus and method for an implantable medical device |
US20020099424A1 (en) * | 2000-12-04 | 2002-07-25 | Bozidar Ferek-Petric | Implantable medical device telemetry control systems and methods of use |
US6636769B2 (en) * | 2000-12-18 | 2003-10-21 | Biosense, Inc. | Telemetric medical system and method |
US6638231B2 (en) * | 2000-12-18 | 2003-10-28 | Biosense, Inc. | Implantable telemetric medical sensor and method |
US20020151770A1 (en) * | 2001-01-04 | 2002-10-17 | Noll Austin F. | Implantable medical device with sensor |
US20020087203A1 (en) * | 2001-01-04 | 2002-07-04 | Steven Schmitt | System and method for receiving telemetry data from an implantable medical device |
US20030199939A1 (en) * | 2001-01-04 | 2003-10-23 | Cardiac Pacemakers, Inc. | System and method for receiving telemetry data from an implantable medical device |
US20020091416A1 (en) * | 2001-01-05 | 2002-07-11 | Wassmund Paul G. | Downloadable software support in a pacemaker |
US20020103514A1 (en) * | 2001-01-31 | 2002-08-01 | St. Jude Medical Ab | Communication system and method for communicating between an implanted medical device and another device |
US20020123776A1 (en) * | 2001-03-02 | 2002-09-05 | Von Arx Jeffrey A. | Antenna for an implantable medical device |
US6622045B2 (en) * | 2001-03-29 | 2003-09-16 | Pacesetter, Inc. | System and method for remote programming of implantable cardiac stimulation devices |
US20020147388A1 (en) * | 2001-04-06 | 2002-10-10 | Mass William R. | Passive telemetry system for implantable medical device |
US20020156504A1 (en) * | 2001-04-20 | 2002-10-24 | Chen Victor T. | Patient controlled atrial shock therapy |
US20030023175A1 (en) * | 2001-05-22 | 2003-01-30 | Arzbaecher Robert C. | Implantable cardiac arrest monitor and alarm system |
US20030006898A1 (en) * | 2001-07-03 | 2003-01-09 | International Business Machines Corporation | Warning method and apparatus |
US20030009204A1 (en) * | 2001-07-06 | 2003-01-09 | Amundson Mark D. | Adapative telemetry system and method for an implantable medical device |
US20030022637A1 (en) * | 2001-07-26 | 2003-01-30 | Kabushiki Kaisha Toshiba | Electronic device and method of mounting radio antenna |
US6614406B2 (en) * | 2001-08-03 | 2003-09-02 | Cardiac Pacemakers, Inc. | Circumferential antenna for an implantable medical device |
US20030025645A1 (en) * | 2001-08-03 | 2003-02-06 | Cardiac Pacemakers, Inc. | Circumferential antenna for an implantable medical device |
US20030114897A1 (en) * | 2001-12-19 | 2003-06-19 | Von Arx Jeffrey A. | Implantable medical device with two or more telemetry systems |
US20030114896A1 (en) * | 2001-12-19 | 2003-06-19 | Wim Boute | System and method for transmission of medical and like data from a patient to a dedicated internet website |
US20030122718A1 (en) * | 2001-12-27 | 2003-07-03 | Shyh-Tirng Fang | Dual-frequency planar antenna |
US20030139778A1 (en) * | 2002-01-22 | 2003-07-24 | Fischell Robert E. | Rapid response system for the detection and treatment of cardiac events |
US20030144718A1 (en) * | 2002-01-29 | 2003-07-31 | Zeijlemaker Volkert A. | Method and apparatus for shielding coating for MRI resistant electrode systems |
US20030149423A1 (en) * | 2002-02-04 | 2003-08-07 | Fischell Robert E. | Methods for the detection and treatment of cardiac events |
US20030199945A1 (en) * | 2002-02-11 | 2003-10-23 | James Ciulla | Device and method for treating disordered breathing |
US20030177031A1 (en) * | 2002-03-15 | 2003-09-18 | Medtronic, Inc. | Data management of patient medical information for use with an implantable medical device |
US20030204216A1 (en) * | 2002-04-25 | 2003-10-30 | Ries Andrew J. | Electrically insulated component sub-assemblies of implantable medical devices |
US6609023B1 (en) * | 2002-09-20 | 2003-08-19 | Angel Medical Systems, Inc. | System for the detection of cardiac events |
US20040122294A1 (en) * | 2002-12-18 | 2004-06-24 | John Hatlestad | Advanced patient management with environmental data |
US20040134496A1 (en) * | 2003-01-10 | 2004-07-15 | Cho Yong K. | Method and apparatus for detecting respiratory disturbances |
US20040138719A1 (en) * | 2003-01-10 | 2004-07-15 | Cho Yong K. | System and method for automatically monitoring and delivering therapy for sleep-related disordered breathing |
US7225013B2 (en) * | 2003-05-15 | 2007-05-29 | Widemed Ltd. | Adaptive prediction of changes of physiological/pathological states using processing of biomedical signals |
US20050061319A1 (en) * | 2003-09-18 | 2005-03-24 | Cardiac Pacemakers, Inc. | Methods and systems for implantably monitoring external breathing therapy |
US20050113710A1 (en) * | 2003-09-18 | 2005-05-26 | Stahmann Jeffrey E. | Implantable device employing movement sensing for detecting sleep-related disorders |
US7115097B2 (en) * | 2003-10-09 | 2006-10-03 | Johnson Joseph L | Positive airway pressure notification system for treatment of breathing disorders during sleep |
US20050085865A1 (en) * | 2003-10-15 | 2005-04-21 | Tehrani Amir J. | Breathing disorder detection and therapy delivery device and method |
US7225021B1 (en) * | 2004-01-30 | 2007-05-29 | Pacesetter, Inc. | Differentiation of central sleep apnea and obstructive sleep apnea using an implantable cardiac device |
US7094207B1 (en) * | 2004-03-02 | 2006-08-22 | Pacesetter, Inc. | System and method for diagnosing and tracking congestive heart failure based on the periodicity of cheyne-stokes respiration using an implantable medical device |
US7179229B1 (en) * | 2004-04-07 | 2007-02-20 | Pacesetter, Inc. | System and method for apnea detection using blood pressure detected via an implantable medical system |
US20060143372A1 (en) * | 2004-12-28 | 2006-06-29 | Walker Robert M | Directed auto-refresh synchronization |
US20070143741A1 (en) * | 2005-12-07 | 2007-06-21 | Microsoft Corporation | Efficient per-object operations in software transactional memory |
US20070239057A1 (en) * | 2006-03-29 | 2007-10-11 | Yanchuan Pu | Periodic disordered breathing detection |
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