US20100016971A1 - Adjustable Spinal Implant - Google Patents
Adjustable Spinal Implant Download PDFInfo
- Publication number
- US20100016971A1 US20100016971A1 US12/566,975 US56697509A US2010016971A1 US 20100016971 A1 US20100016971 A1 US 20100016971A1 US 56697509 A US56697509 A US 56697509A US 2010016971 A1 US2010016971 A1 US 2010016971A1
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- United States
- Prior art keywords
- row
- apertures
- tubular body
- end portion
- threaded surface
- Prior art date
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- Abandoned
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/46—Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor
- A61F2/4603—Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor for insertion or extraction of endoprosthetic joints or of accessories thereof
- A61F2/4611—Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor for insertion or extraction of endoprosthetic joints or of accessories thereof of spinal prostheses
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- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
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- A61F2/44—Joints for the spine, e.g. vertebrae, spinal discs
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- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
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- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
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- A61F2002/30411—Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements made by screwing complementary threads machined on the parts themselves having two threaded end parts connected by a threaded central part with opposite threads at its opposite ends, i.e. for adjusting the distance between both end parts by rotating the central part
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- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
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- A61F2002/30316—The prosthesis having different structural features at different locations within the same prosthesis; Connections between prosthetic parts; Special structural features of bone or joint prostheses not otherwise provided for
- A61F2002/30535—Special structural features of bone or joint prostheses not otherwise provided for
- A61F2002/30537—Special structural features of bone or joint prostheses not otherwise provided for adjustable
- A61F2002/3055—Special structural features of bone or joint prostheses not otherwise provided for adjustable for adjusting length
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- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
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- A61F2002/30316—The prosthesis having different structural features at different locations within the same prosthesis; Connections between prosthetic parts; Special structural features of bone or joint prostheses not otherwise provided for
- A61F2002/30535—Special structural features of bone or joint prostheses not otherwise provided for
- A61F2002/30593—Special structural features of bone or joint prostheses not otherwise provided for hollow
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- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
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- A61F2002/30535—Special structural features of bone or joint prostheses not otherwise provided for
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- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/30767—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth
- A61F2/30771—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth applied in original prostheses, e.g. holes or grooves
- A61F2002/30772—Apertures or holes, e.g. of circular cross section
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- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
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Definitions
- the present invention concerns medical procedures and instruments used during surgery. More particularly, a novel apparatus and method is provided for adjusting an adjustable vertebral implant.
- spinal injuries and deformities can occur due to trauma, disease or congenital effects.
- one type of spinal deformity a kyphosis
- This destruction can be in the form of a trauma type injury, such as a fracture or burst injury to the vertebral body, or a non-traumatic deformity caused by a tumor or a degeneration of the bone in the vertebral body.
- a kyphosis in the thoracic or lumbar spine appears now to be best achieved through an anterior approach, particularly in order to avoid some of the more severe complications associated with support or replacement of a damaged vertebral body.
- a high degree of anterior reconstruction of the spine is required, most frequently involving total removal of the damaged vertebral body.
- partial or total ablation of the vertebral body and the two adjacent vertebral discs is carried out.
- a vertebral implant assembly may be used to restore the vertebral column to the correct orientation.
- the implant disclosed in the Rabbe patent is an adjustable vertebral implant assembly configured to span the void created by the removed vertebral body and discs.
- the assembly includes a thin-walled tubular body which defines a hollow interior and further includes endplates with end surfaces configured to engage the tubular body between the adjacent vertebrae. In some embodiments, the end surfaces defines a bore through the endplate.
- an expansion assembly expands a vertebral implant.
- the vertebral implant has an inner cylindrical assembly adapted for insertion into an outer cylindrical assembly having an outer wall.
- the vertebral implant is expandable along an implant axis defined by the outer and inner cylindrical assemblies.
- the expansion assembly comprises an axle having proximal and distal end portions and an axle axis defined between the proximal and distal end portions.
- the expansion assembly further comprises a gear arranged about the axle axis at the proximal end portion of the axle and adapted to rotate about the axle axis to cause the inner cylindrical assembly to expand the vertebral implant.
- the engagement assembly also comprising a first engaging portion adapted to engage the inner cylindrical assembly and a second engaging portion adapted to engage the gear externally of the outer wall of the outer cylindrical assembly.
- a method for installing a vertebral implant between adjacent vertebrae comprises providing a vertebral implant having an inner cylindrical body extending into an outer cylindrical body.
- the outer cylindrical body has an outer wall and the bodies defining an implant axis.
- the method further includes providing an expansion assembly.
- the expansion assembly comprises an axle having proximal and distal end portions and an axle axis defined between the proximal and distal end portions.
- the expansion assembly also includes a secondary gear assembly attached to the proximal end portion and a main gear assembly engaged with the secondary gear assembly externally of the outer wall.
- the method further includes engaging the main gear assembly with the inner cylindrical body and rotating the axle about the axle axis to cause the inner cylindrical body to move relative to the outer cylindrical body along the implant axis.
- an instrument is adapted for installing a vertebral implant.
- the implant has at least one outer tubular assembly threadedly engaged with an inner tubular assembly.
- the instrument comprises an axle having proximal and distal ends and an axle axis defined between the proximal and distal ends.
- the instrument also comprises a gear assembly connected to the proximal end of the axle and adapted to rotate the inner tubular assembly to expand the vertebral implant. The inner tubular assembly is rotated without extending the gear assembly into the at least one outer tubular assembly.
- FIG. 1 is an perspective view of a destroyed vertebral body within a vertebral column (in shadow) and a vertebral implant assembly according to one embodiment of the present invention positioned within the vertebral column.
- FIG. 2 a perspective view of a vertebral implant assembly coupled with a portion of an expansion apparatus according to one embodiment of the present invention.
- FIG. 3 is a perspective view of an expansion apparatus according to an embodiment of the present invention.
- FIG. 4 is a cross-sectional view of a portion of the expansion apparatus of FIG. 3 .
- FIG. 5 is a partial cross-section of a portion of the expansion apparatus of FIG. 3 .
- FIGS. 6 a and 6 b are perspective views of a holding instrument used with the expansion apparatus of FIG. 3 .
- a vertebral column 10 includes a damaged vertebra 12 a (shown in phantom) extending between a vertebra 12 b and a vertebra 12 c .
- An intervertebral disc 14 a (shown in phantom) extends between vertebrae 12 a and 12 b
- an intervertebral disc 14 b (shown in phantom) extends between vertebrae 12 a and 12 c .
- the vertebra 12 a can be removed together with discs 14 a and 14 b creating a void between the two intact vertebra 12 b and 12 c .
- This procedure may be performed using an anterior, anterolateral, or other approach known to one skilled in the art.
- a vertebral implant assembly 20 as described in the Rabbe patent can then be provided to fill the void between the two intact vertebrae 12 b and 12 c.
- the implant assembly 20 generally includes a threaded tubular body 22 extending between threaded endplate assemblies 24 and 26 .
- the threaded tubular body 22 is provided with a plurality of apertures 28 that may be used for installation of the assembly 20 and that may also provide an avenue for bone or tissue ingrowth to further enhance the stability of the replacement assembly after implantation.
- the opposite ends of the tubular body 22 are formed into external threads 30 .
- the threads 30 may extend from each opposite end over most or all of the length of the tubular body 22 and may be configured to threadedly engage endplate assemblies 24 and 26 .
- the endplate assembly 24 may include a flange 32 , which may cover a substantial load-bearing area of the endplates of the adjacent intact vertebral bodies.
- a cylinder 34 may be integrally formed with flange 32 to extend toward the threaded tubular body 22 when the endplate assembly 24 is placed within the excised vertebral space.
- the cylinder 34 and flange 32 define a bore 36 there through.
- the inside surface of the bore 36 is provided with internal threads 38 which are configured to mate with the external threads 30 of the tubular body 22 .
- the threads 38 extend along the entire length of the cylinder 34 and into the flange 32 .
- Endplate assembly 26 may be configured similar or identical to endplate assembly 24 and therefore will not be described in detail.
- the endplate assemblies 24 and 26 may further include one or more apertures 40 configured to engage a holding instrument (as described below for FIGS. 6 a and 6 b ).
- the external threads 30 on the threaded tubular body 22 may be cut in opposite directions (e.g., right handed and left handed) so that the endplates can be drawn together or apart by rotating only the body.
- the threads 30 at each of the ends engage the internal threads 38 of each of the end caps 24 and 26 in the proper direction to draw the end caps together.
- the handedness of the threads 30 can be the same at each end so that it is necessary to individually thread each end cap in opposite directions onto the tubular body 22 .
- the disadvantage of this arrangement is that it is more difficult to adjust the height of the total assembly 20 while maintaining the proper orientation of each of the endplate assemblies 24 and 26 .
- An advantage is that in situ the assembly is unable to unthread itself. Further details of the assembly 20 and its operation are described in the embodiments shown in the Rabbe patent.
- the assembly 20 may be inserted into the vertebral column (as shown in FIG. 1 ) and then expanded to achieve the desired fit and alignment between the adjacent intact vertebrae.
- expansion of the assembly can be achieved by rotating the tubular body 22 using an expander apparatus 50 as shown in FIG. 3 .
- the expander apparatus 50 includes a handle section 52 , an extension section 54 , a main gear box 56 and an engager 58 .
- the expander apparatus 50 may allow the assembly 20 to be adjusted without the use of lateral movement, thereby reducing the size of a patient's wound and decreasing the time and labor involved to complete the procedure.
- the handle section 52 can receive and enclose a portion of the extension section 54 .
- the extension section 54 may comprise an outer casing 60 through which an interior axle 62 may extend.
- the handle section 52 may include a handle 64 that receives, surrounds and rotationally engages the outer casing 60 of the extension section 54 through one or more bushings 66 .
- the rotational engagement of the outer casing 60 may be accomplished using ball bearing assemblies and/or the material comprising the handle 64 .
- the handle 64 may be separated into two independent portions, with one portion being fixed to the outer casing 60 to secure and position the expander apparatus 50 during use, and the other portion being free to rotate for providing the rotational force discussed below.
- the handle section 52 may further include a distally located selector gear box 70 .
- the selector gear box 70 may include a set or plurality of gears 72 a , 72 b , 72 c configured to selectively engage with the distal end of the interior axle 62 of the extension section 54 .
- Each of the gears 72 a , 72 b , and 72 c may be of a different size so that a user of the expander apparatus 50 may choose from a range of selectable gear ratios, enabling the user to achieve a desired speed or torque for adjusting the vertebral implant assembly 20 .
- the selector gear box 70 may be configured to engage with a cap member 74 .
- the cap member 74 can be both axially and rotationally movable about the handle 64 and can further include a gear selection member 76 which, as the cap member 74 is moved, can engage any of the different gears 72 a , 72 b , or 72 c to create the desired gear ratio.
- the present embodiment depicts three gears, it is understood that in other embodiments a fewer or a greater number of gears may be used. Further, any of a variety of gear train systems may be employed incorporating a variety of gear components such as a planetary gear systems, a layshaft, a clutch, a worm gear system, a bevel gear system, a rack and pinion system, or other gear based systems.
- the cap member 74 rotates or translates about the handle 64 to select a particular gear, but other gear selection mechanisms can also be used.
- the selector gear box may not be located in the handle section 52 , but rather, may be included in the extension section 54 or elsewhere in the expander tool 50 .
- the selector gear box 70 may be omitted and the distal end of the axle 62 may be fixedly engaged with the gear selection cap 74 and/or a rotating portion of the handle section 52 .
- the rotation of the axle 62 may be directly driven by rotation of the gear selection cap 74 .
- the axle 62 may be driven by a motor coupled to the axle 62 or to the selector gear box 70 .
- the main gear box 56 may include a main gear/tooth assembly 80 and a secondary gear assembly 82 .
- the main gear/tooth assembly 80 can be partially enclosed and secured within a casing 83 , and can include a gear section 84 coaxially attached to a toothed section 86 .
- the casing 83 may include a pin 88 about which the main gear/tooth assembly 80 can rotate.
- the rotational axis of the pin 88 and the gear section 84 may be aligned perpendicular to the rotational axis of the axle 62 , although different embodiments may have different arrangements.
- the secondary gear assembly 82 may be attached to the proximate end of the interior axle 62 , opposite from the end engaged with the selector gear box 70 , and may rotate about the axis of the axle 62 .
- the secondary gear assembly 82 may engage with the gear section 84 of the main gear/tooth assembly 80 causing any rotational force from the axle 62 to be transferred to the main gear/tooth assembly 80 .
- the main gear box 56 can be further connected to the engager 58 .
- the casing 83 of the main gear box 56 may be attached to a positioning mechanism 90 , which in the embodiment of FIG. 2 is shaped like a semi-circle with opposing arc portions 92 a and 92 b .
- the arc portions 92 a and 92 b can define a cross-section of an engagement area 91 into which the implant assembly 20 may be positioned.
- the positioning mechanism 90 is shaped to mate with the tubular body 22 of the implant assembly 20 , allowing the tubular body 22 to rotate while assisting in maintaining the general position and proximity of the engager 58 to the tubular body 22 .
- the casing 83 may cover only a portion of the main gear/tooth assembly 80 .
- the other portion which can include the tooth section 86 , may extend into the engagement area 91 of the engager 58 .
- the tooth section 86 may include a plurality of teeth 93 that are sized, spaced, and shaped to engage the apertures 28 on the tubular body 22 when the tubular body 22 is positioned in the engagement area 91 .
- the positioning mechanism 90 and the arrangement of the apertures 28 can minimize any translation of the tubular body 22 , ensuring that the next tooth 93 easily locates and engages the next aperture 28 , to thereby maintain the rotation.
- the teeth 93 are radially arranged on the tooth section 86 in a gear-like configuration.
- a toothed belt or another gripping mechanism can be used to drive the rotation of the tubular body 22 .
- the positioning mechanism 90 is shaped more like a “C.” In these embodiments, the positioning mechanism 90 also helps to prevent the engager 58 from accidentally disengaging from the replacement assembly 20 .
- the opposing arc portions 92 a , 92 b are selectively pivotable about pins 94 a and 94 b with friction keeping the arc portions 92 a , 92 b either open or closed. In the open position, the tubular body 22 can be positioned in or removed from the engagement area 91 . In the closed position, the arc portions 92 a and 92 b aid in keeping the positioning mechanism 90 engaged to the tubular body 22 while the body rotates. It is understood, that other embodiments may use a clip, a spring, or some other means of engagement to selectively allow the positioning mechanism 90 to remain engaged.
- the positioning mechanism 90 may be configured to more securely maintain the desired position of implant assembly 20 .
- the positioning mechanism 90 may extend laterally along the tubular body 22 to restrain the assembly 20 from pivoting about its longitudinal axis.
- Another example e.g. FIGS. 6 a and 6 b ) may include a second positioning mechanism 90 extending from the casing 83 in which case the assembly 20 can be held in position by arc positions both above and below the tooth section 86 .
- the expander apparatus 50 may be positioned within the surgical area proximate to the implant assembly 20 . It is understood, however, that in some instances the expander apparatus 50 can be used to facilitate the placement of the assembly 20 inside the vertebral column 10 .
- the expander apparatus 50 is positioned so that the engager 58 is engaged with the tubular body 22 of the implant assembly 20 . Specifically, at least one of the teeth 93 may engage one of the apertures 28 .
- the handle 60 can extend away from the vertebral column 10 , for example, in an anterior surgical approach, the handle may be positioned in the anterior area of the patient, within easy reach of the surgeon.
- the surgeon can rotate or axially translate the cap member 74 to engage the appropriate gear 72 a , 72 b , 72 c to achieve the desired gear ratio, although it is understood that in some embodiments the selector gear box 70 can be omitted.
- the surgeon can then turn either the handle 64 or the rotatably movable portion of the handle 64 around the axis of the interior axle 62 to expand (or contract, if necessary) the implant assembly 20 .
- the rotation of the handle 64 or handle portion is transferred through the gear box 70 to rotate the axle 62 .
- the axle rotates the secondary gear assembly 82 , which rotates the gear section 84 .
- the rotation of the gear section 84 causes the fixedly attached tooth section 86 to rotate which, in turn moves the teeth 93 .
- the movement of the teeth 93 can cause the tubular body 20 to rotate which may cause the endplate assemblies 24 and 26 to move relative to one another, thereby expanding, contracting, or otherwise adjusting the implant assembly 20 .
- a holding instrument 100 may be coupled to the expander apparatus 50 to hold the implant assembly 20 in position during the expansion, all the while minimizing backlash or lateral movement of the assembly 20 .
- the holding instrument can be attached to the extension section 54 by an attachment device 102 which may include one or more rings 104 configured for fastening to the outer casing 60 .
- the one or more rings 104 may be fixedly attached to the extension section with one or more fastening mechanisms 106 which can be, for example, screws.
- the fastening mechanisms 106 may engage a protrusion (not shown) extending from the outer casing 60 .
- a plurality of expansion members 108 may connect the attachment device 102 to a pair of alignment arms 110 and 112 .
- Each expansion member 108 may be a rigid bar pivotally connected at one end to the attachment device 102 and at the opposite end to one of the alignment arms 110 or 112 .
- the expansion member may be a spring, an elastic member, or another mechanism capable of expanding with the alignment arms 110 and 112 as the implant 20 is expanded.
- An alignment member 114 may further extend between the alignment arms 110 and 112 and may be adjustable to maintain a relatively parallel alignment of the alignment arms.
- Each of the alignment arms 110 and 112 extend toward the engagement area 91 where the ends of each alignment arm 110 and 112 are configured with holding assemblies 116 and 118 , respectively.
- the holding assemblies 116 and 118 may be arc-shaped to accept the assembly 20 and may further include fasteners 120 for engaging the apertures 40 on the endplate assemblies 24 and 26 to maintain the assembly 20 in a generally rigid vertical position while the assembly 20 is expanded.
- the fasteners may be, for example, pins, screws, or clamps.
- the holding assemblies 116 and 118 may fasten to the endplate assemblies 24 and 26 without engaging the apertures 40 .
- the expander apparatus 50 with the attached holding instrument 100 may be positioned within the surgical area proximate to the implant assembly 20 . It is understood, however, that in some instances the expander apparatus 50 and holding instrument 100 can be used to facilitate the placement of the assembly 20 inside the vertebral column 10 .
- the expander apparatus 50 is positioned so that the engager 58 is engaged with the tubular body 22 of the implant assembly 20 . Specifically, at least one of the teeth 93 may engage one of the apertures 28 .
- the pins 120 may be engaged with the apertures 40 on the endplate assemblies 24 and 26 .
- the handle 60 can extend away from the vertebral column 10 , for example, in an anterior surgical approach, the handle may be positioned in the anterior area of the patient, within easy reach of the surgeon.
- the surgeon can rotate or axially translate the cap member 74 to engage the appropriate gear 72 a , 72 b , 72 c to achieve the desired gear ratio. It is understood that in some embodiments the selector gear box 70 can be omitted.
- the surgeon can then rotate either the handle 64 or the rotatably movable portion of the handle 64 along the axis of the interior axle 62 to expand (or contract, if necessary) the implant assembly 20 .
- the rotation of the handle 64 or handle portion is transferred through the gear box 70 to rotate the axle 62 .
- the axle rotates the secondary gear assembly 82 , which rotates the gear section 84 .
- the rotation of the gear section 84 causes the fixedly attached tooth section 86 to rotate which, in turn moves the teeth 93 .
- the movement of the teeth 93 can cause the tubular body 20 to rotate, which in turn can cause the endplate assemblies 24 and 26 to move relative to one another, thereby expanding (or contracting, if necessary) the implant assembly 20 .
- the expansion members 108 may pivot to allow the alignment arms 110 and 112 to move apart while remaining in relatively parallel alignment.
- the alignment member 114 may adjust to further preserve the parallel alignment of the alignment arms 110 and 112 .
Abstract
An expansion assembly expands a vertebral implant. The vertebral implant has an inner cylindrical assembly adapted for insertion into an outer cylindrical assembly having an outer wall. The vertebral implant is expandable along an implant axis defined by the outer and inner cylindrical assemblies. The expansion assembly comprises an axle having proximal and distal end portions and an axle axis defined between the proximal and distal end portions. The expansion assembly further comprises a gear arranged about the axle axis at the proximal end portion of the axle and adapted to rotate about the axle axis to cause the inner cylindrical assembly to expand the vertebral implant. The engagement assembly also comprising a first engaging portion adapted to engage the inner cylindrical assembly and a second engaging portion adapted to engage the gear externally of the outer wall of the outer cylindrical assembly.
Description
- This application is a Divisional of U.S. Ser. No. 11/286,887, filed on Nov. 23, 2005 and incorporated by reference herein, which is a Continuation of U.S. Ser. No. 10/663,554, filed on Sep. 16, 2003 and incorporated by reference herein, which claims the benefit of U.S. Provisional Application No. 60/412,730 filed on Sep. 23, 2002 and incorporated by reference herein.
- The present invention concerns medical procedures and instruments used during surgery. More particularly, a novel apparatus and method is provided for adjusting an adjustable vertebral implant.
- A variety of spinal injuries and deformities can occur due to trauma, disease or congenital effects. For example, one type of spinal deformity, a kyphosis, involves a prolapse of the vertebral column towards the front of the body, often caused by the destruction of the vertebral body itself. This destruction can be in the form of a trauma type injury, such as a fracture or burst injury to the vertebral body, or a non-traumatic deformity caused by a tumor or a degeneration of the bone in the vertebral body.
- Treatment of a kyphosis in the thoracic or lumbar spine appears now to be best achieved through an anterior approach, particularly in order to avoid some of the more severe complications associated with support or replacement of a damaged vertebral body. In most treatments of a kyphosis, a high degree of anterior reconstruction of the spine is required, most frequently involving total removal of the damaged vertebral body. In a typical anterior approach, partial or total ablation of the vertebral body and the two adjacent vertebral discs is carried out. Following this vertebrectomy, a vertebral implant assembly may be used to restore the vertebral column to the correct orientation.
- One implant that may be used is disclosed in U.S. Pat. No. 6,344,057 to Rabbe et al. (“Rabbe patent”), which is hereby incorporated by reference. The implant disclosed in the Rabbe patent is an adjustable vertebral implant assembly configured to span the void created by the removed vertebral body and discs. The assembly includes a thin-walled tubular body which defines a hollow interior and further includes endplates with end surfaces configured to engage the tubular body between the adjacent vertebrae. In some embodiments, the end surfaces defines a bore through the endplate.
- Current surgical spinal reconstruction techniques can use a plurality of wrenches to expand or otherwise manipulate rotationally adjustable implants, such as the assembly disclosed in the Rabbe patent. However, a wrench requires lateral translation which, in the confined area of the wound, can require an enlarged wound and increased labor and time. It must also relocate and reattach to the implant after each turn, which is both difficult and time consuming.
- In one embodiment of the present disclosure, an expansion assembly expands a vertebral implant. The vertebral implant has an inner cylindrical assembly adapted for insertion into an outer cylindrical assembly having an outer wall. The vertebral implant is expandable along an implant axis defined by the outer and inner cylindrical assemblies. The expansion assembly comprises an axle having proximal and distal end portions and an axle axis defined between the proximal and distal end portions. The expansion assembly further comprises a gear arranged about the axle axis at the proximal end portion of the axle and adapted to rotate about the axle axis to cause the inner cylindrical assembly to expand the vertebral implant. The engagement assembly also comprising a first engaging portion adapted to engage the inner cylindrical assembly and a second engaging portion adapted to engage the gear externally of the outer wall of the outer cylindrical assembly.
- In another embodiment, a method for installing a vertebral implant between adjacent vertebrae comprises providing a vertebral implant having an inner cylindrical body extending into an outer cylindrical body. The outer cylindrical body has an outer wall and the bodies defining an implant axis. The method further includes providing an expansion assembly. The expansion assembly comprises an axle having proximal and distal end portions and an axle axis defined between the proximal and distal end portions. The expansion assembly also includes a secondary gear assembly attached to the proximal end portion and a main gear assembly engaged with the secondary gear assembly externally of the outer wall. The method further includes engaging the main gear assembly with the inner cylindrical body and rotating the axle about the axle axis to cause the inner cylindrical body to move relative to the outer cylindrical body along the implant axis.
- In still another embodiment, an instrument is adapted for installing a vertebral implant. The implant has at least one outer tubular assembly threadedly engaged with an inner tubular assembly. The instrument comprises an axle having proximal and distal ends and an axle axis defined between the proximal and distal ends. The instrument also comprises a gear assembly connected to the proximal end of the axle and adapted to rotate the inner tubular assembly to expand the vertebral implant. The inner tubular assembly is rotated without extending the gear assembly into the at least one outer tubular assembly.
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FIG. 1 is an perspective view of a destroyed vertebral body within a vertebral column (in shadow) and a vertebral implant assembly according to one embodiment of the present invention positioned within the vertebral column. -
FIG. 2 a perspective view of a vertebral implant assembly coupled with a portion of an expansion apparatus according to one embodiment of the present invention. -
FIG. 3 is a perspective view of an expansion apparatus according to an embodiment of the present invention. -
FIG. 4 is a cross-sectional view of a portion of the expansion apparatus ofFIG. 3 . -
FIG. 5 is a partial cross-section of a portion of the expansion apparatus ofFIG. 3 . -
FIGS. 6 a and 6 b are perspective views of a holding instrument used with the expansion apparatus ofFIG. 3 . - Referring to
FIG. 1 , avertebral column 10 includes a damagedvertebra 12 a (shown in phantom) extending between avertebra 12 b and avertebra 12 c. Anintervertebral disc 14 a (shown in phantom) extends betweenvertebrae intervertebral disc 14 b (shown in phantom) extends betweenvertebrae vertebra 12 a can be removed together withdiscs intact vertebra vertebral implant assembly 20 as described in the Rabbe patent can then be provided to fill the void between the twointact vertebrae - Referring now to
FIG. 2 , thevertebral implant assembly 20 is shown as a turnbuckle in accordance with one embodiment of the present invention. Theimplant assembly 20 generally includes a threadedtubular body 22 extending between threadedendplate assemblies tubular body 22 is provided with a plurality ofapertures 28 that may be used for installation of theassembly 20 and that may also provide an avenue for bone or tissue ingrowth to further enhance the stability of the replacement assembly after implantation. In the present embodiment, the opposite ends of thetubular body 22 are formed intoexternal threads 30. Thethreads 30 may extend from each opposite end over most or all of the length of thetubular body 22 and may be configured to threadedly engageendplate assemblies - The
endplate assembly 24 may include aflange 32, which may cover a substantial load-bearing area of the endplates of the adjacent intact vertebral bodies. Acylinder 34 may be integrally formed withflange 32 to extend toward the threadedtubular body 22 when theendplate assembly 24 is placed within the excised vertebral space. Thecylinder 34 andflange 32 define abore 36 there through. The inside surface of thebore 36 is provided withinternal threads 38 which are configured to mate with theexternal threads 30 of thetubular body 22. In one embodiment, thethreads 38 extend along the entire length of thecylinder 34 and into theflange 32.Endplate assembly 26 may be configured similar or identical toendplate assembly 24 and therefore will not be described in detail. Theendplate assemblies more apertures 40 configured to engage a holding instrument (as described below forFIGS. 6 a and 6 b). - In one specific embodiment, the
external threads 30 on the threadedtubular body 22 may be cut in opposite directions (e.g., right handed and left handed) so that the endplates can be drawn together or apart by rotating only the body. Thus, as the body is rotated in one direction, thethreads 30 at each of the ends engage theinternal threads 38 of each of the end caps 24 and 26 in the proper direction to draw the end caps together. Alternatively, the handedness of thethreads 30 can be the same at each end so that it is necessary to individually thread each end cap in opposite directions onto thetubular body 22. The disadvantage of this arrangement is that it is more difficult to adjust the height of thetotal assembly 20 while maintaining the proper orientation of each of theendplate assemblies assembly 20 and its operation are described in the embodiments shown in the Rabbe patent. - The
assembly 20 may be inserted into the vertebral column (as shown inFIG. 1 ) and then expanded to achieve the desired fit and alignment between the adjacent intact vertebrae. In one embodiment, expansion of the assembly can be achieved by rotating thetubular body 22 using anexpander apparatus 50 as shown inFIG. 3 . - Referring now to
FIG. 3 , in accordance with one embodiment of the present invention, theexpander apparatus 50 includes ahandle section 52, anextension section 54, amain gear box 56 and anengager 58. Theexpander apparatus 50 may allow theassembly 20 to be adjusted without the use of lateral movement, thereby reducing the size of a patient's wound and decreasing the time and labor involved to complete the procedure. - Referring to both
FIG. 3 andFIG. 4 , thehandle section 52 can receive and enclose a portion of theextension section 54. In the present embodiment, theextension section 54 may comprise anouter casing 60 through which aninterior axle 62 may extend. Thehandle section 52 may include ahandle 64 that receives, surrounds and rotationally engages theouter casing 60 of theextension section 54 through one ormore bushings 66. It is understood that in other embodiments, the rotational engagement of theouter casing 60 may be accomplished using ball bearing assemblies and/or the material comprising thehandle 64. Although not shown, in some embodiments, thehandle 64 may be separated into two independent portions, with one portion being fixed to theouter casing 60 to secure and position theexpander apparatus 50 during use, and the other portion being free to rotate for providing the rotational force discussed below. - In the present embodiment, the
handle section 52 may further include a distally locatedselector gear box 70. Theselector gear box 70 may include a set or plurality ofgears interior axle 62 of theextension section 54. Each of thegears expander apparatus 50 may choose from a range of selectable gear ratios, enabling the user to achieve a desired speed or torque for adjusting thevertebral implant assembly 20. Theselector gear box 70 may be configured to engage with acap member 74. Thecap member 74 can be both axially and rotationally movable about thehandle 64 and can further include agear selection member 76 which, as thecap member 74 is moved, can engage any of thedifferent gears - Although the present embodiment depicts three gears, it is understood that in other embodiments a fewer or a greater number of gears may be used. Further, any of a variety of gear train systems may be employed incorporating a variety of gear components such as a planetary gear systems, a layshaft, a clutch, a worm gear system, a bevel gear system, a rack and pinion system, or other gear based systems. In the present embodiment, the
cap member 74 rotates or translates about thehandle 64 to select a particular gear, but other gear selection mechanisms can also be used. In some embodiments, the selector gear box may not be located in thehandle section 52, but rather, may be included in theextension section 54 or elsewhere in theexpander tool 50. - Although not shown, in another embodiment, the
selector gear box 70 may be omitted and the distal end of theaxle 62 may be fixedly engaged with thegear selection cap 74 and/or a rotating portion of thehandle section 52. In this embodiment, the rotation of theaxle 62 may be directly driven by rotation of thegear selection cap 74. In still another embodiment, theaxle 62 may be driven by a motor coupled to theaxle 62 or to theselector gear box 70. - Referring now to
FIG. 5 , while one end of theextension section 54 engages with thehandle section 52, the opposite end may engage with themain gear box 56. Themain gear box 56 may include a main gear/tooth assembly 80 and asecondary gear assembly 82. The main gear/tooth assembly 80 can be partially enclosed and secured within acasing 83, and can include agear section 84 coaxially attached to atoothed section 86. Thecasing 83 may include apin 88 about which the main gear/tooth assembly 80 can rotate. In the present embodiment, the rotational axis of thepin 88 and thegear section 84 may be aligned perpendicular to the rotational axis of theaxle 62, although different embodiments may have different arrangements. - The
secondary gear assembly 82 may be attached to the proximate end of theinterior axle 62, opposite from the end engaged with theselector gear box 70, and may rotate about the axis of theaxle 62. Thesecondary gear assembly 82 may engage with thegear section 84 of the main gear/tooth assembly 80 causing any rotational force from theaxle 62 to be transferred to the main gear/tooth assembly 80. - Referring to
FIGS. 2 and 5 , themain gear box 56 can be further connected to theengager 58. Thecasing 83 of themain gear box 56 may be attached to apositioning mechanism 90, which in the embodiment ofFIG. 2 is shaped like a semi-circle with opposingarc portions arc portions engagement area 91 into which theimplant assembly 20 may be positioned. Thepositioning mechanism 90 is shaped to mate with thetubular body 22 of theimplant assembly 20, allowing thetubular body 22 to rotate while assisting in maintaining the general position and proximity of the engager 58 to thetubular body 22. - As described above, the
casing 83 may cover only a portion of the main gear/tooth assembly 80. The other portion, which can include thetooth section 86, may extend into theengagement area 91 of theengager 58. Thetooth section 86 may include a plurality ofteeth 93 that are sized, spaced, and shaped to engage theapertures 28 on thetubular body 22 when thetubular body 22 is positioned in theengagement area 91. With the endplate assemblies at least tentatively affixed to the adjacent vertebral endplates, thetubular body 22 can rotate as thetooth section 86 is rotated. Furthermore, thepositioning mechanism 90 and the arrangement of theapertures 28 can minimize any translation of thetubular body 22, ensuring that thenext tooth 93 easily locates and engages thenext aperture 28, to thereby maintain the rotation. In the present embodiment, theteeth 93 are radially arranged on thetooth section 86 in a gear-like configuration. In other embodiments, a toothed belt or another gripping mechanism can be used to drive the rotation of thetubular body 22. - Referring more specifically to
FIG. 5 , in some embodiments, thepositioning mechanism 90 is shaped more like a “C.” In these embodiments, thepositioning mechanism 90 also helps to prevent the engager 58 from accidentally disengaging from thereplacement assembly 20. In one embodiment, the opposingarc portions pins arc portions tubular body 22 can be positioned in or removed from theengagement area 91. In the closed position, thearc portions positioning mechanism 90 engaged to thetubular body 22 while the body rotates. It is understood, that other embodiments may use a clip, a spring, or some other means of engagement to selectively allow thepositioning mechanism 90 to remain engaged. - In some embodiments, the
positioning mechanism 90 may be configured to more securely maintain the desired position ofimplant assembly 20. For example, thepositioning mechanism 90 may extend laterally along thetubular body 22 to restrain theassembly 20 from pivoting about its longitudinal axis. Another example (e.g.FIGS. 6 a and 6 b) may include asecond positioning mechanism 90 extending from thecasing 83 in which case theassembly 20 can be held in position by arc positions both above and below thetooth section 86. - Referring now to
FIGS. 1-5 , in operation, once theimplant assembly 20 is placed in position between the endplates of the twoadjacent vertebrae FIG. 1 ), theexpander apparatus 50 may be positioned within the surgical area proximate to theimplant assembly 20. It is understood, however, that in some instances theexpander apparatus 50 can be used to facilitate the placement of theassembly 20 inside thevertebral column 10. Theexpander apparatus 50 is positioned so that the engager 58 is engaged with thetubular body 22 of theimplant assembly 20. Specifically, at least one of theteeth 93 may engage one of theapertures 28. Thehandle 60 can extend away from thevertebral column 10, for example, in an anterior surgical approach, the handle may be positioned in the anterior area of the patient, within easy reach of the surgeon. - After the expander apparatus is in place, the surgeon can rotate or axially translate the
cap member 74 to engage theappropriate gear selector gear box 70 can be omitted. The surgeon can then turn either thehandle 64 or the rotatably movable portion of thehandle 64 around the axis of theinterior axle 62 to expand (or contract, if necessary) theimplant assembly 20. Specifically, the rotation of thehandle 64 or handle portion is transferred through thegear box 70 to rotate theaxle 62. The axle, in turn, rotates thesecondary gear assembly 82, which rotates thegear section 84. The rotation of thegear section 84, causes the fixedly attachedtooth section 86 to rotate which, in turn moves theteeth 93. With theendplate assemblies endplate assemblies teeth 93 can cause thetubular body 20 to rotate which may cause theendplate assemblies implant assembly 20. - Referring now to
FIGS. 6 a and 6 b, in this embodiment, a holdinginstrument 100 may be coupled to theexpander apparatus 50 to hold theimplant assembly 20 in position during the expansion, all the while minimizing backlash or lateral movement of theassembly 20. The holding instrument can be attached to theextension section 54 by anattachment device 102 which may include one ormore rings 104 configured for fastening to theouter casing 60. The one ormore rings 104 may be fixedly attached to the extension section with one ormore fastening mechanisms 106 which can be, for example, screws. In one alternative embodiment, to avoid interference with theinterior axle 62 running through theextension section 54, thefastening mechanisms 106 may engage a protrusion (not shown) extending from theouter casing 60. - A plurality of
expansion members 108 may connect theattachment device 102 to a pair ofalignment arms expansion member 108 may be a rigid bar pivotally connected at one end to theattachment device 102 and at the opposite end to one of thealignment arms alignment arms implant 20 is expanded. Analignment member 114 may further extend between thealignment arms alignment arms engagement area 91 where the ends of eachalignment arm assemblies assemblies assembly 20 and may further includefasteners 120 for engaging theapertures 40 on theendplate assemblies assembly 20 in a generally rigid vertical position while theassembly 20 is expanded. The fasteners may be, for example, pins, screws, or clamps. In some embodiments, the holdingassemblies endplate assemblies apertures 40. - Referring still to
FIGS. 6 a and 6 b, in operation, once theimplant assembly 20 is placed in position between the endplates of the twoadjacent vertebrae FIG. 1 ), theexpander apparatus 50 with the attached holdinginstrument 100 may be positioned within the surgical area proximate to theimplant assembly 20. It is understood, however, that in some instances theexpander apparatus 50 and holdinginstrument 100 can be used to facilitate the placement of theassembly 20 inside thevertebral column 10. Theexpander apparatus 50 is positioned so that the engager 58 is engaged with thetubular body 22 of theimplant assembly 20. Specifically, at least one of theteeth 93 may engage one of theapertures 28. To further secure theimplant assembly 20, thepins 120 may be engaged with theapertures 40 on theendplate assemblies handle 60 can extend away from thevertebral column 10, for example, in an anterior surgical approach, the handle may be positioned in the anterior area of the patient, within easy reach of the surgeon. - After the expander apparatus is in place, the surgeon can rotate or axially translate the
cap member 74 to engage theappropriate gear selector gear box 70 can be omitted. The surgeon can then rotate either thehandle 64 or the rotatably movable portion of thehandle 64 along the axis of theinterior axle 62 to expand (or contract, if necessary) theimplant assembly 20. Specifically, the rotation of thehandle 64 or handle portion is transferred through thegear box 70 to rotate theaxle 62. The axle, in turn, rotates thesecondary gear assembly 82, which rotates thegear section 84. The rotation of thegear section 84, causes the fixedly attachedtooth section 86 to rotate which, in turn moves theteeth 93. - With the
endplate assemblies instrument 100, the movement of theteeth 93 can cause thetubular body 20 to rotate, which in turn can cause theendplate assemblies implant assembly 20. As theimplant assembly 20 expands, theexpansion members 108 may pivot to allow thealignment arms alignment arms alignment member 114 may adjust to further preserve the parallel alignment of thealignment arms implant assembly 20 has attained the desired height, the pins may be removed from theapertures 40, disconnecting the holdinginstrument 100 from theimplant assembly 20. - Although only a few exemplary embodiments of this invention have been described in detail above, those skilled in the art will readily appreciate that many modifications are possible in the exemplary embodiments without materially departing from the novel teachings and advantages of this invention. Accordingly, all such modifications are intended to be included within the scope of this invention.
Claims (20)
1. A vertebral implant for expansion between two vertebral bodies, comprising:
a first end plate component including a first cylindrical portion, the first cylindrical portion comprising a first threaded surface;
a second end plate component including a second cylindrical portion, the second cylindrical portion comprising a second threaded surface; and
a tubular body comprising a first end portion and a second end portion and including a central hollow bore, the tubular body having a longitudinally extending axis, the tubular body having a threaded surface at the first end portion and at the second end portion,
the threaded surface at the first end portion threadably engaging the first threaded surface of the first end plate, the threaded surface at the second end portion threadably engaging the second threaded surface of the second end plate,
the tubular body comprising a plurality of apertures extending from an exterior of tubular body to the hollow bore, the plurality of apertures being sized and configured to receive a driving tool, the plurality of apertures being arranged in at least adjacent first and second rows, the first row and the second row being axially offset along the longitudinal axis, the plurality of apertures of the first row also being radially offset from the plurality of apertures of the second row.
2. The vertebral implant of claim 1 , wherein the plurality of apertures are further arranged in a third row, the third row being axially offset along the longitudinal axis from both the first row and the second row and located such that the second row is disposed between and adjacent to both the first and third rows, the plurality of apertures of the third row being radially offset from the plurality of apertures of the second row and being radially aligned with the plurality of apertures of the first row.
3. The vertebral implant of claim 1 , wherein the first threaded surface of the first end plate is an inwardly facing surface and wherein the second threaded surface of the second end plate is an inwardly facing surface.
4. The vertebral implant of claim 3 , wherein the threaded body surface is an outwardly facing surface.
5. The vertebral implant of claim 4 , wherein the plurality of apertures are formed through threads on the threaded outer facing surface of the tubular body.
6. The vertebral implant of claim 1 , wherein each of the first and second end plates includes a flange sized to fit against a substantial load bearing portion of a vertebral endplate.
7. The vertebral implant of claim 6 , wherein the flange and the cylindrical portions are integrally formed.
8. The vertebral implant of claim 1 , wherein the threads on the threaded surface of the tubular body extend substantially along a length of the tubular body from the first end portion to the second end portion.
9. The vertebral implant of claim 1 , wherein the threads on the threaded surface of the tubular body are cut in opposite directions such that the endplates can be drawn together or apart by rotating only the tubular body.
10. The vertebral implant of claim 1 , wherein the threads at the first end portion and at the second end portion of the tubular body are cut in the same direction.
11. The vertebral implant of claim 1 , wherein the flange comprises a flange bore extending therethrough, the flange bore being in communication with the hollow bore of the tubular member.
12. A vertebral implant for expansion between two vertebral bodies, comprising:
a first end plate component including a first cylindrical portion, the first cylindrical portion comprising a first threaded surface; and
a tubular body comprising a first end portion and a second end portion, the tubular body having a longitudinally extending axis, the tubular body having a threaded surface at the first end portion, the threaded surface at the first end portion threadably engaging the first threaded surface of the first end plate,
the tubular body comprising a plurality of apertures extending inwardly from an exterior of tubular body, the plurality of apertures being sized and configured to receive a driving tool, the plurality of apertures being arranged in at least adjacent first and second rows, the first row and the second row being axially offset along the longitudinal axis, the plurality of apertures of the first row also being radially offset from the plurality of apertures of the second row.
13. The vertebral implant of claim 12 , comprising a second end plate component associated with the second end portion of the tubular body.
14. The vertebral implant of claim 12 , wherein the plurality of apertures are further arranged in a third row, the third row being axially offset along the longitudinal axis from both the first row and the second row and located such that the second row is disposed between and adjacent to both the first and third rows, the plurality of apertures of the third row being radially offset from the plurality of apertures of the second row and also being radially aligned with the plurality of apertures of the first row.
15. The vertebral implant of claim 12 , wherein the first threaded surface is an inwardly facing surface.
16. The vertebral implant of claim 15 , wherein the threaded body surface is an outer facing surface.
17. The vertebral implant of claim 16 , wherein the plurality of apertures are formed through threads on the threaded outer facing surface of the tubular body.
18. A vertebral implant for expansion between two vertebral bodies, comprising:
a first end plate component including a first flange and a first cylindrical portion, the first cylindrical portion comprising an inwardly facing first threaded surface, the first flange being sized to fit against a substantial load bearing portion of an upper vertebral endplate;
a second end plate component including a second flange and a second cylindrical portion, the second cylindrical portion comprising an inwardly facing second threaded surface, the second flange being sized to fit against a substantial load bearing portion of a lower vertebral endplate;
a tubular body comprising a first end portion and a second end portion and including a central hollow bore, the tubular body having a longitudinally extending axis, the tubular body having an outwardly facing threaded surface extending from the first end portion to the second end portion,
the outer facing threaded surface at the first end portion threadably engaging the inwardly facing first threaded surface of the first end plate, the outer facing threaded surface at the second end portion threadably engaging the inwardly facing second threaded surface of the second end plate,
the tubular body comprising a plurality of apertures extending through the outwardly facing threads on the exterior of the tubular body to the hollow bore, the plurality of apertures being sized and configured to receive a driving tool, the plurality of apertures being arranged in at least first, second, and third rows, the second row being adjacent both the first and third rows, the first, second, and third rows being axially offset along the longitudinal axis, the plurality of apertures of the second row also being radially offset from the plurality of apertures of the first row and the third row, the plurality of apertures of the third row being radially aligned with the plurality of apertures of the first row.
19. The vertebral implant of claim 18 , wherein the flange and the cylindrical portions are integrally formed.
20. The vertebral implant of claim 18 , wherein each of the first and second end plate components comprises a bore extending therethrough, the bore being in communication with the hollow bore of the tubular member.
Priority Applications (1)
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US12/566,975 US20100016971A1 (en) | 2002-09-23 | 2009-09-25 | Adjustable Spinal Implant |
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US11/286,887 US7608078B2 (en) | 2002-09-23 | 2005-11-23 | Expansion apparatus for adjustable spinal implant |
US12/566,975 US20100016971A1 (en) | 2002-09-23 | 2009-09-25 | Adjustable Spinal Implant |
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US12/566,975 Abandoned US20100016971A1 (en) | 2002-09-23 | 2009-09-25 | Adjustable Spinal Implant |
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US11/286,887 Expired - Fee Related US7608078B2 (en) | 2002-09-23 | 2005-11-23 | Expansion apparatus for adjustable spinal implant |
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EP (1) | EP1551340B1 (en) |
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US8152852B2 (en) * | 2006-09-14 | 2012-04-10 | The University Of Toledo | Variable height vertebral body replacement implant |
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US8377140B2 (en) | 2011-01-12 | 2013-02-19 | Ebi, Llc | Expandable spinal implant device |
US9968460B2 (en) | 2013-03-15 | 2018-05-15 | Medsmart Innovation Inc. | Dynamic spinal segment replacement |
US11602436B2 (en) | 2015-03-23 | 2023-03-14 | Musc Foundation For Research Development | Expandable vertebral body replacement device and method |
US11278424B2 (en) | 2016-11-28 | 2022-03-22 | Musc Foundaton For Research Development | Expandable vertebral body replacement device and method |
US11554025B1 (en) * | 2019-08-19 | 2023-01-17 | Nuvasive, Inc. | Expandable implant expansion driver |
US11896501B2 (en) * | 2019-08-19 | 2024-02-13 | Nuvasive Inc. | Expandable implant expansion driver |
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US11918489B2 (en) * | 2021-04-02 | 2024-03-05 | Nuvasive Inc. | Expansion driver |
Also Published As
Publication number | Publication date |
---|---|
AU2003275196A1 (en) | 2004-04-08 |
EP1551340B1 (en) | 2008-12-17 |
US7608078B2 (en) | 2009-10-27 |
CA2500326A1 (en) | 2004-04-01 |
US7588573B2 (en) | 2009-09-15 |
EP1551340A2 (en) | 2005-07-13 |
US20060084975A1 (en) | 2006-04-20 |
WO2004026157A3 (en) | 2004-04-29 |
WO2004026157A2 (en) | 2004-04-01 |
US20040059271A1 (en) | 2004-03-25 |
ATE417580T1 (en) | 2009-01-15 |
DE60325401D1 (en) | 2009-01-29 |
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