US20090222076A1 - Self-Expandable Medical Instrument for Treating of Defects in a Patient's Heart - Google Patents
Self-Expandable Medical Instrument for Treating of Defects in a Patient's Heart Download PDFInfo
- Publication number
- US20090222076A1 US20090222076A1 US12/084,421 US8442106A US2009222076A1 US 20090222076 A1 US20090222076 A1 US 20090222076A1 US 8442106 A US8442106 A US 8442106A US 2009222076 A1 US2009222076 A1 US 2009222076A1
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- United States
- Prior art keywords
- medical instrument
- stent
- heart valve
- mesh
- patient
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- Abandoned
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Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
- A61F2/2412—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body with soft flexible valve members, e.g. tissue valves shaped like natural valves
- A61F2/2418—Scaffolds therefor, e.g. support stents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
- A61F2/2427—Devices for manipulating or deploying heart valves during implantation
- A61F2/2436—Deployment by retracting a sheath
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/95—Instruments specially adapted for placement or removal of stents or stent-grafts
- A61F2002/9528—Instruments specially adapted for placement or removal of stents or stent-grafts for retrieval of stents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2230/00—Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2230/0063—Three-dimensional shapes
- A61F2230/0073—Quadric-shaped
- A61F2230/0078—Quadric-shaped hyperboloidal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2230/00—Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2230/0063—Three-dimensional shapes
- A61F2230/0073—Quadric-shaped
- A61F2230/008—Quadric-shaped paraboloidal
Abstract
Description
- The present invention relates to a self-expandable medical instrument for treating defects in a patient's heart, in particular for the transvascular implantation of a prosthetic heart valve, whereby the medical instrument can be introduced via a catheter system into the patient's body in a minimally-invasive procedure. In particular, the invention relates to a device for the transvascular replacement of diseased heart valves.
- A device of this type is known in principle to medical technology. At present, biological or mechanical valve models are available to substitute for human heart valves which are usually fixedly sewn into the bed of the heart valve during a surgical procedure through an opening in the thorax after removal of the diseased heart valve. In this surgical procedure, the patient's circulation must be maintained by a heart-lung machine, whereby cardiac arrest is induced during the implantation of the prosthetic heart valve. This consequently makes the surgical procedure a risky one coupled with the associated risks for the patients and a lengthy post-operative treatment phase. In particular, the risks of such a surgical procedure are often no longer justifiable in the case of multimorbid patients.
- Minimally-invasive treatment procedures of recent development are characterized in particular by the surgery being able to be performed under local anesthesia. One approach provides for implanting a self-expanding stent connected to a collapsible heart valve into the human body by means of an appropriate catheter system. The catheter systems is used to guide such a self-expanding prosthetic heart valve through the inguinal artery or vein to its site of implantation at the heart. After reaching the site of implantation, the stent, consisting for example of a plurality of self-expanding stent segments which can be bent relative one another in its longitudinal direction, can then be successively expanded. Following this expansion, anchoring hooks can for example support the anchoring of the prosthetic heart valve at least in the respective blood vessel close to the heart. The actual prosthetic heart valve itself is thereby in the direct proximal area of the stent.
- Known for example from the DE 100 10 074 A1 printed publication is a device for fastening and anchoring prosthetic heart valves, which is essentially formed from wire-shaped interconnected elements. The device thereby provides for using various different arched elements in order to attain a secure fixation of and support for the prosthetic heart valve. To this end, the device described in this printed publication makes use of three identical pairs of arched elements, arranged to be offset from one another by 120°. These arched elements are interconnected by means of solid articulations, whereby the solid articulations fulfill the function of pivot bearings. Additional arched elements bent opposite to each other are furthermore provided which form rocker arms as equal in length as possible in order to achieve a secure placement of the arched elements even when subject to peristaltic actions on the heart and blood vessels and a solid sealing for an implanted and anchored prosthetic heart valve.
- In the known solutions, however, there is a risk of heart valve implant malalignment. This essentially relates to the exact positioning and longitudinal orientation of the prosthetic heart valve to be implanted. In particular, it is only with immense skill on the part of the attending surgeon—if at all—that a stent with the prosthetic heart valve at its proximal end winds up being positioned so precisely in the proximity of the patient's diseased heart valve that both sufficient lateral positioning accuracy as well as a suitable longitudinal placement to the prosthetic heart valve can be optimally ensured.
- Among other complications, an implantation malalignment of a less than optimally positioned prosthetic heart valve can lead to, for example, leakage or valvular regurgitation, which puts a substantial burden on the ventricle. Should, for example, a prosthetic heart valve be implanted too far above the actual heart valve plane, this can lead to occlusion of the coronary artery origination (coronaries) and thus to a fatal coronary ischemia with myocardial infarction. It is therefore imperative for an implanted prosthetic heart valve to meet all the respective requirements for both the accuracy of the lateral positioning as well as the longitudinal placement.
- In conventional implantation techniques in which self-expandable prosthetic heart valves are, for example, guided through a patient's inguinal artery to the site of deployment at the heart in a minimally-invasive procedure, the prosthesis is usually introduced using a guide wire and catheters, whereby conventional balloon catheters can also be used. Although such a surgical introduction can be monitored and controlled, for example with fluoroscopy (Cardiac Catheterization Laboratory=CCL) or with ultrasound (Transesophageal Echocardiogram=TEE), oftentimes—due to the limited maneuverability of the prosthetic heart valve which is still in a collapsed state during the introduction procedure and despite being in the collapsed state is still of relatively large size—it is not possible to ensure the required positioning accuracy and especially the longitudinal placement to the prosthetic heart valve implant with the corresponding anchoring elements affixed thereto. In particular—as a result of a possible coronary artery occlusion—an angle misalignment to the implanted prosthetic heart valve from the optimum site of deployment can pose a threat to the respective patient.
- In designing a prosthetic heart valve, special consideration must in particular be given to the substantial forces also acting on the prosthetic during the filling period of the cardiac cycle (diastole), necessitating a secure anchorage in order to prevent the implanted prosthetic heart valve from dislodging.
- Hence on the one hand, the prosthetic heart valve must be able to be maneuvered to the greatest extent possible in the respective coronary artery during the implantation procedure so as to ensure optimum positioning accuracy and, on the other hand, the implanted prosthesis must be able to be firmly anchored at its site of implantation in order to effectively prevent subsequent prosthesis misalignment.
- The present invention addresses the problem that the known devices for transvascular implantation and fixation of prosthetic heart valves are often not suitable for a simple implantation of a prosthetic heart valve with the required positioning accuracy. Moreover, explanting a previously implanted prosthetic heart valve in a minimally-invasive procedure or accordingly correcting an incorrectly positioned prosthetic heart valve has to date often only been possible with great effort, if at all.
- On the basis of the problems as set forth, one task on which the present invention is based is that of providing a device for the transvascular implantation and fixation of prosthetic heart valves which remedies the above-described disadvantages inherent to conventional implantation systems.
- According to the invention, this task is solved by a medical self-expandable instrument for treating heart defects in a patient, in particular for the transvascular implantation of a prosthetic heart valve, whereby the medical instrument can be introduced into the patient's body in a minimally-invasive procedure using a catheter system and a stent made from a flexible mesh of thin wires or filaments. It is thereby provided for the stent or the mesh to exhibit a first predefinable shape while the medical instrument is being inserted into the patient's body and a second predefinable shape when the medical instrument is in its implanted state, whereby the medical instrument is in a collapsed state in the first shape of the stent or mesh and in an expanded state in the second shape of the stent or mesh. In particular, in its expanded state, the medical instrument according to the inventive solution exhibits a distal retention area with a laterally-inverted beaded portion, which in the implanted state of the medical instrument is engageable with at least one pocket of the patient's defective heart valve, a proximal retention area, as well as a center area positioned between the distal and the proximal retention area. In its expanded state, the center area of the medical instrument thereby exhibits a smaller diameter than the proximal and/or distal retention area, whereby in the implanted state of the medical instrument at the height of the patient's defective heart valve, the center area is designed to form a positive connection with the vascular wall at or in the direct proximity of the defective heart valve.
- The advantages of the invention are in particular noted to be in the providing of a transvascularly introducible medical instrument, in particular for treating a patient's heart defects, whereby the medical instrument is suitable to be delivered by catheter to the defect to be treated in the patient's heart. Because the medical instrument is configured as a self-expandable instrument and essentially consists of a stent made of a flexible mesh of thin wires or filaments, one particularly advantageous result achieved is that the medical instrument—regardless of the size of the heart valve to be treated and regardless of the diameter to the defective heart valve—can self-adapt to the defective heart valve, and in such a way that, on the one hand, the portions of the medical instrument protruding into the bloodstream flowing past the implanted medical instrument are as small as possible, while at the same time, an optimal positioning, secure anchorage and optimal lateral sealing of the implanted medical instrument is ensured.
- Accordingly, the medical instrument is optimally positionable at the defective heart valve and anchored there in extremely stable manner, whereby at the same time, embolism-related problems can be prevented. Using thin wires or filaments as the source material of the stent or the medical instrument according to the invention respectively yields the further advantage of the medical instrument exhibiting long-term mechanical stability. This thus sustainably prevents structural fractures from occurring in the instrument employed. The mesh furthermore has sufficient rigidity.
- Briefly summarized, the solution according to the invention is characterized by the medical instrument comprising a stent made from a flexible mesh, in particular a wire mesh, which upon release from the catheter inverts in mushroom-shape form into the pockets of the diseased heart valve and is clamped there by this inversion. This thus provides an optimum positioning and stable anchoring of a prosthetic heart valve disposed or provided in the middle of the stent. At the same time, an optimum lateral sealing of the implanted prosthetic valve is ensured.
- Preferred embodiments of the medical instrument are indicated in the subclaims.
- A particularly preferred realization of the medical instrument according to the invention accordingly provides for the stent to furthermore exhibit a self-expandable prosthetic heart valve arranged in the center area which self-expands upon the medical instrument being released from the catheter system and which then assumes the function of the patient's defective heart valve. In this preferred embodiment, the mesh thus serves the medical instrument as a heart valve stent in the anchoring and positioning of the prosthetic heart valve arranged in the center area of the medical instrument. The medical instrument is in particular characterized by the fact that, due to its shape in the expanded state, it not only provides an extremely stable anchoring of the prosthetic heart valve, but also a self-positioning of same at the height of the defective heart valve to be replaced.
- With respect to the mesh which forms the prosthetic heart valve stent, it is preferably provided for same to be a mesh tube such that the medical instrument exhibits a form open to the proximal and distal end in its expanded state. A mesh tube offers the advantage of blood being able to flow through the medical instrument in the implanted state of the expanded medical instrument, whereby—except for the prosthetic heart valve disposed in the center area of the medical instrument—virtually no foreign components protrude into the bloodstream.
- It is furthermore conceivable for the beaded portion at the distal retention area of the stent in the expanded medical instrument to be formed by the mushroom-shaped outwardly turned-back distal end of the mesh. In particular, the beaded portion at the distal retention area of the expanded medical instrument in the implanted state of the medical instrument is thereby invertible in the at least one pocket of the patient's defective heart valve and thus serves as a self-positioning means for positioning the medical instrument at the height of the patient's defective heart valve.
- According to a further aspect of the present invention, because of the self-expanding properties of the stent made from the flexible mesh, the proximal retention area of the stent forms a force-fit connection with the vascular wall when the medical instrument is in its expanded state, thus ensuring a stable anchoring of the implanted medical instrument.
- On the other hand, the center area of the stent in the expanded medical instrument is advantageously configured such that based on the self-expanding properties of the stent made from the flexible mesh, the center area presses the patient's defective heart valve against the vascular wall distal the defective heart valve in the implanted state of the medical instrument.
- With respect to the shape of the medical instrument in its expanded state, the stent in its second shape respectively, it is preferable for same to be of a shape similar to a barbell, whereby both the distal as well as the proximal retention area are respectively configured in the shape of a mushroom cap. It is furthermore preferred for the center area of the stent to exhibit a smaller diameter in the expanded medical instrument compared to the proximal and distal retention areas, whereby the center area exhibits a length which corresponds approximately to the length of the defective heart valve.
- It is particularly preferred for the mesh-based stent having a self-expandable prosthetic heart valve arranged at its center area to taper to the diameter of the catheter system used in the transvascular surgical procedure.
- In order to allow for a medical instrument already implanted into the body of the patient being able to be subsequently explanted, a preferred further development of the solution according to the invention provides for the stent to exhibit a mounting engageable with an explantation catheter system on its proximal and/or distal end, wherein the medical instrument is moreover configured such that an external manipulation will effect its alteration from the expanded state to its collapsed state so that the medical instrument, the stent with the prosthetic heart valve respectively, will be as simple as possible to explant.
- A further aspect of the invention provides for the flexible mesh forming the stent for the self-expandable medical instrument to have a multi-layered configuration around the patient's defective heart valve in the implanted state of the medical instrument.
- Because a stent formed from a flexible mesh is used and because of the self-expanding properties to the medical instrument thus attained, it is particularly preferable for the stent with the self-expandable prosthetic heart valve arranged at its center area to be configured such that in the implanted state of the expanded medical instrument, the second shape of the stent, and thus the medical instrument, adapts to the anatomical conditions in such a manner that the prosthetic heart valve attains a maximum expansion on the one hand and, on the other, an optimum lateral sealing to the vascular wall is provided.
- It is of particular advantage for the stent made of flexible mesh, in particular wire mesh, with a self-expanding prosthetic heart valve arranged in its center area to be configured such that the stent with the prosthetic heart valve can be withdrawn back into the catheter system, and thus removable from the patient's body, at any time during the implantation of the medical instrument.
- It is provided for the flexible mesh to be made from nitinol or another material having shape-memory or memory effect. Other applicable materials would include, for example, copper/zinc/aluminum alloys, gold/cadmium alloys or also iron-based alloys such as, for example, iron/manganese, silicon alloys, as well as also plastics, which are all characterized by the fact that they have extremely high memory capabilities.
- Lastly, with regard to the use of the medical instrument, it is particularly preferred for the flexible stent of mesh with the prosthetic heart valve at its center area to be used not only for replacing aorta valves but also mitral, pulmonary and tricuspid valves.
- The following will make reference to the accompanying figures in describing the invention in greater detail, wherein the figures are as follows:
-
FIG. 1 shows a preferred embodiment of the medical instrument according to the invention during insertion into the body of a patient, whereby the flexible mesh, which here forms the aorta valve stent, exhibits its first predefined shape; -
FIG. 2 shows the medical instrument ofFIG. 1 in a first state in which the aorta valve stent is released from the insertion catheter system; -
FIG. 3 shows the medical instrument ofFIG. 2 in a further second state during the release of the aorta valve stent from the insertion catheter system; -
FIG. 4 shows the medical instrument ofFIG. 3 in a further advanced third state during the release of the aorta valve stent from the insertion catheter system; -
FIG. 5 shows a state in which the aorta valve stent and thus the medical instrument according toFIGS. 1 to 4 is fully expanded and implanted at the height of the patient's heart valve; -
FIG. 6 shows a perspective view of the expanded medical instrument according to the preferred embodiment; -
FIG. 7 shows a conceivable route of implantation for the medical instrument according to the preferred embodiment. - The embodiment depicted in the figures of the inventive self-expandable
medical instrument 100 for treating defects of a patient's heart relates to a self-expandable medical instrument for the transvascular implantation of aprosthetic heart valve 30, wherein themedical instrument 100 can be introduced into a patient's body in minimally-invasive fashion by means of acatheter system 40 and consists of a stent 1 made from a flexible mesh (2) of thin wires or filaments 2′. - As
FIG. 1 shows, the stent 1 configured from flexible mesh 2 is in a first predefined shape during the insertion of themedical instrument 100 into the patient's body. The stent 1 further exhibits a self-expandableprosthetic heart valve 30 at itscenter area 15, which is covered by mesh 2 inFIG. 1 and thus not explicitly shown. As will be described below, the self-expandableprosthetic heart valve 30 unfolds by itself upon themedical instrument 100, the stent 1 respectively, being released from thecatheter system 40. - What can in particular be noted from
FIG. 1 is that the stent 1 configured from mesh 2 with theprosthetic heart valve 30 arranged at its center area 15 (not explicitly shown inFIG. 1 ) tapers to the diameter of thecatheter system 40 used for the transvascular procedure. In this state, themedical instrument 100 is seen as being in its collapsed state. -
FIG. 1 specifically depicts a state immediately prior to themedical instrument 100 in its collapsed state being brought through thedefective aorta valve 50 of the patient to the ascending aorta by means of aguide wire 41, and after themedical instrument 100 having been transseptally inserted into the left ventricle by aninsertion catheter system 40. As already indicated, only the flexible mesh 2 can be recognized in the depiction of themedical instrument 100 shown in theFIG. 1 representation, same assuming the function of the aorta valve stent 1 and with the (not explicitly depicted) collapsedprosthetic heart valve 50 disposed at itscenter area 15. -
FIG. 2 shows a state in which—starting from the position shown in FIG. 1—the first portion of the inner wire mesh 2 of stent 1 is mushroomed out of the correspondinginsertion catheter system 40, whereby this portion forms the beadedportion 12 at thedistal retention area 10 of the stent in the fully expanded state ofmedical instrument 100, arching laterally in a mushroom shape. In the implanted state ofmedical instrument 100, the laterally outward cappingbeaded portion 12 engages in at least onepocket 51 of the patient'sdefective heart valve 50, as will be described in detail below. -
FIG. 3 shows a further state in which the entire stent 1 is drawn back to the height of thedefective aorta valve 50, where thedefective valve 50 is hooked in form-fit manner to the “midriff” of stent 1; i.e., thecenter area 15 of the double-mushroomed stent 1 after full expansion, after the distal (upper) portion of the wire mesh 2 inverts into place and the beadedportion 12 is fully formed. -
FIG. 4 meanwhile shows a state in which by the further extending of stent 1 formed from the mesh 2 out of thecatheter system 40, the self-expandableprosthetic heart valve 30 disposed in thecenter area 15 within stent 1 emerges. In this state, the patient's defective (old)valve 50 engages with themidsectioned center area 15 of stent 1. The beadedportion 12 at thedistal retention area 10 of stent 1 is furthermore turned inside out by the mushroom-shaped inverting of the distal end of mesh 2, whereby the beadedportion 12 turns to fit into thepockets 51 of the patient'sdefective heart valve 50 so as to serve as a means for positioning themedical instrument 100 at the height of the patient'sdefective heart valve 50. - Upon stent 1 being further extended from the
catheter system 40, theproximal retention area 20 of stent 1 finally unfolds, whereby same then forms a force-fit connection with thevascular wall 52 in the direct proximity of thedefective heart valve 50 due to the self-expanding properties of the mesh 2. At the same time, thecenter area 15 of stent 1 presses against theaorta wall 52, whereby the self-expandable mesh 2 expands further, thereby clamping theprosthetic valve 30. - Both
FIG. 5 a andFIG. 5 b show a state in which the mechanicalprosthetic heart valve 30 is correctly positioned and fully closed, whereby the defective (old)valve 50 remains in the heart and is pressed against thevascular wall 52. Moreover indicated is how, following a check of the proper seating and the error-free functioning of the mechanicalprosthetic heart valve 30, theguide wire 41 can then be removed again. It is hereby pointed out that in the event of valve malfunction, theguide wire 41 can retract stent 1 with the integratedprosthetic heart valve 30 back into the insertion catheter system as necessary and the stent can be replaced by another stent with an integrated prosthetic heart valve. -
FIG. 6 shows a perspective view of the expandedmedical instrument 100 in accordance with the preferred embodiment. It can be recognized that in the expanded state ofmedical instrument 100, the stent 1 exhibits a barbell-like shape, whereby the stent 1 formed from the flexible mesh 2 with the self-expandableprosthetic heart valve 30 disposed within thecenter area 15 of stent 1 (not recognizable inFIG. 6 ) is configured such that the second shape of stent 1 in the implanted state of the expandedmedical instrument 100 can adapt to the anatomical conditions in such a manner that theprosthetic heart valve 30 attains maximum expansion on the one hand and, on the other, achieves an optimum lateral sealing tovascular wall 52. - It can further be noted from
FIG. 6 that in the expanded state ofmedical instrument 100, thecenter area 15 of stent 1 exhibits a smaller diameter than the proximal anddistal retention areas center area 15 exhibits a length which corresponds approximately to the length of thedefective heart valve 50. - The embodiment of the
medical instrument 100 as depicted moreover provides for the stent 1 to have a mounting 4 in the form of a ring at its proximal end which can be brought into engagement with a (not shown) explantation catheter system, whereby themedical instrument 100 is configured such that external manipulation can commute it from its expanded state into its collapsed state. -
FIG. 7 shows how aguide wire 41 can be fed through the vena cava to the right atrium and the interatrial septum in the left atrium and further into the left ventricle and from there through the left ventricular outflow tract and the aorta valve to the ascending aorta. - It is particularly preferred for the transvascular replacement of a patient's
defective aorta valve 50, for example, to sew or otherwise fasten a suitableprosthetic valve 30 in the middle of thecenter area 15 of the stent 1 configured from flexible mesh 2. The stent 1 with the integratedprosthetic valve 30 can then be tapered to the diameter of thecatheter system 40 used in the transvascular surgical procedure and brought through the venous system, passing the interatrial septum, from the right atrium into the left atrium and from there, further into the left ventricle and the left ventricular outflow tract by means of the insertion catheter system. - The stent 1 configured from mesh 2 is released from the
insertion catheter system 40 at the height of the defective (old)aorta valve 50, as is shown inFIG. 1 . Because stent 1 is discharged successively, at first only thedistal retention area 10 is released such that it upends inside out in mushroom shape, as depicted inFIGS. 2 to 4 . Subsequent thereto, a careful guiding of themedical instrument 100 toward the ventricles will bring the beadedportion 12 into a form-fit connection in thepockets 51 of the patient's defectiveold valve 50. The middle midriff, thecenter area 15 respectively, of stent 1, in which theprosthetic valve 30 is disposed, is now in form-fit seating at the height of the old heart valve (50), as shown inFIG. 4 . - The
proximal retention area 20 of stent 1 is then also subsequently ejected from thecatheter system 40, whereby the artificialprosthetic valve 30 expands and at the same time, the olddefective heart valve 50 is pressed againstwall 52 due to the self-expanding properties of the wire mesh 2 (cf.FIG. 5 ). In this state, the beaded orflanged portion 12 at thedistal retention area 10 turns inversely outward into the left ventricular outflow tract and thus effects an additional mechanical support and secure anchorage for the medical instrument. In the event of any malfunctioning of stent 1 with the integratedprosthetic valve 30, theguide wire 41 still tethered to stent 1 can effect its removal as necessary, as is indicated inFIGS. 5 a and 5 b. - It is not imperative to have the route of implantation for the double-mushroom-shaped heart valve stent 1 be transvenous and through the interatrial septum. It is just as conceivable to perform a retrograde implantation procedure through the aortic arch with a
catheter system 40 in the manner as described above. The heart valve stent 1 constructed in this manner with its givenmedial midriff 15 furthermore offers the opportunity of the integrated mounting (ring) of stent 1 subsequently re-fixing onto the integratedprosthetic heart valve 30 and collapsing same by the longitudinal extension of the wire mesh such that it can be removed again through a catheter tube. - The entire detailed route of implantation is depicted in
FIG. 7 . Aguide wire 41 is first introduced through the venous system to the right atrium and through the interatrial septum into the left atrium. From the left atrium, the guide wire is pushed through the left ventricle and the left ventricular outflow tract into the aorta (FIG. 7 ). Using theguide wire 41 as a rail, theinsertion catheter 40 is now advanced into the left ventricular outflow tract and the aortic valve plane. The implantation of the valve as described above now follows. - Alternatively, a
guide wire 41 coming from the aortic arch can be pushed in retrograde manner through the aortic valve into the left ventricle. A similar implantation of the aortic valve stent 1 as indicated above is now possible here with a modified catheter tube. - By a design-contingent integration of retaining elements on the self-expandable stent 1, same can also be explanted again with a special catheter subsequent a successful implantation. To this end, the distal or
proximal retention area guide wire 41 into acatheter 40 at a plurality of, preferably more than three retaining punctures. In so doing, reversed as in implantation, the mushroom-shapedproximal beaded portion 22 at theproximal retention area 20 of stent 1 is buffeted back, whereby the wire mesh 2 expands again and assumes a state as shown inFIG. 4 . Subsequently, the engagement or anchoring of the beadedportion 12 ondistal retention area 10 of stent 1 with thepockets 51 of the body's own defective heart valve can be disengaged. - The stent 1 composed of the flexible wire mesh 2 with the
prosthetic valve 30 integrated in itscenter area 15 and adapted to the valve ring and, where necessary, to the outflow tract of the human heart, can be used in similar fashion for replacing mitral valves as well as replacing pulmonary or tricuspid valves. - It is obvious that the following features in particular distinguish the solution according to the invention over the medical instruments as known to date for the transvascular replacement of diseased heart valves:
-
- 1. With the stent configured from the self-expandable mesh with a prosthetic valve disposed in the middle thereof, the old diseased heart valve is enfolded, reversely pushed in and pressed against the vascular wall.
- 2. The prosthetic valve in the stent can be implanted both in antegrade (via transseptal puncture) as well as retrograde procedures.
- 3. The stent, the flexible mesh respectively, optimally self-adapts to the anatomical conditions of the valve ring and the heart's outflow tract, which thereby achieves a better lateral sealing for the implanted medical instrument.
- 4. In the event of the prosthetic valve malfunctioning, the stent with the integrated prosthetic valve can be retracted back through the insertion catheter system and removed completely from the patient's body.
- 5. Compared to conventional stent valves, the great degree of flexibility to the wire mesh allows implantation even in the case of highly angular approaches.
- 6. The self-expanding wire mesh can be used to replace both the valves of the left as well as the right ventricle and to replace both the atrioventricular valve as well as also the semilunar valve of the heart, since it flexibly adapts to the anatomical conditions and surrounds the old diseased valve.
- 7. Reversely pushing in the old diseased valve into the self-expanding wire mesh prevents embolization of portions of the old valve.
- 8. The design-contingent integration of retaining elements on the self-expanding wire mesh also allows for same to be explanted again with a special catheter subsequent a successful implantation.
- It is pointed out that the realization of the invention is not restricted to the embodiments described with reference to
FIGS. 1 to 7 , but is also possible in a plurality of other variants. -
- 1 stent
- 2 mesh
- 2′ filaments/wire of the mesh
- 4 mounting
- 10 distal retention area of the stent
- 12 beaded portion at the distal retention area
- 15 center area of the stent
- 20 proximal retention area of the stent
- 22 beaded portion at the proximal retention area
- 30 prosthetic valve
- 40 catheter system
- 41 guide wire
- 50 body's own heart valve
- 51 pocket of body's own heart valve
- 52 vascular wall
- 100 medical instrument
Claims (17)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE102005052628.4A DE102005052628B4 (en) | 2005-11-04 | 2005-11-04 | Self-expanding, flexible wire mesh with integrated valvular prosthesis for the transvascular heart valve replacement and a system with such a device and a delivery catheter |
DE102005052628.4 | 2005-11-04 | ||
PCT/EP2006/010519 WO2007051620A1 (en) | 2005-11-04 | 2006-11-02 | Self-expandable medical instrument for treatment of defects on a patient’s heart |
Publications (1)
Publication Number | Publication Date |
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US20090222076A1 true US20090222076A1 (en) | 2009-09-03 |
Family
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Application Number | Title | Priority Date | Filing Date |
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US12/084,421 Abandoned US20090222076A1 (en) | 2005-11-04 | 2006-11-02 | Self-Expandable Medical Instrument for Treating of Defects in a Patient's Heart |
US11/592,369 Active 2028-02-13 US8062355B2 (en) | 2005-11-04 | 2006-11-03 | Self-expandable medical instrument for treating defects in a patient's heart |
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Application Number | Title | Priority Date | Filing Date |
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US11/592,369 Active 2028-02-13 US8062355B2 (en) | 2005-11-04 | 2006-11-03 | Self-expandable medical instrument for treating defects in a patient's heart |
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US (2) | US20090222076A1 (en) |
EP (1) | EP1942834B1 (en) |
JP (1) | JP4904362B2 (en) |
AU (1) | AU2006310681B2 (en) |
CA (1) | CA2627555C (en) |
DE (1) | DE102005052628B4 (en) |
DK (1) | DK1942834T3 (en) |
ES (1) | ES2401451T3 (en) |
PL (1) | PL1942834T3 (en) |
PT (1) | PT1942834E (en) |
SI (1) | SI1942834T1 (en) |
WO (1) | WO2007051620A1 (en) |
Cited By (181)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20060173524A1 (en) * | 2003-12-23 | 2006-08-03 | Amr Salahieh | Medical Implant Delivery And Deployment Tool |
US20060271166A1 (en) * | 2005-05-27 | 2006-11-30 | Heart Leaflet Technologies, Inc. | Stentless support structure |
US20090210047A1 (en) * | 2008-02-18 | 2009-08-20 | Aga Medical Corporation | Stent graft for reinforcement of vascular abnormalities and associated method |
US7914575B2 (en) | 2007-04-13 | 2011-03-29 | Jenavalve Technology, Inc. | Medical device for treating a heart valve insufficiency |
US20110137397A1 (en) * | 2009-12-04 | 2011-06-09 | Edwards Lifesciences Corporation | Prosthetic valve for replacing mitral valve |
US7988724B2 (en) | 2003-12-23 | 2011-08-02 | Sadra Medical, Inc. | Systems and methods for delivering a medical implant |
US20110218620A1 (en) * | 2010-03-05 | 2011-09-08 | Edwards Lifesciences Corporation | Retaining Mechanisms for Prosthetic Valves |
US8052749B2 (en) | 2003-12-23 | 2011-11-08 | Sadra Medical, Inc. | Methods and apparatus for endovascular heart valve replacement comprising tissue grasping elements |
US8136659B2 (en) | 2005-09-13 | 2012-03-20 | Sadra Medical, Inc. | Two-part package for medical implant |
US8163008B2 (en) | 2002-08-28 | 2012-04-24 | Heart Leaflet Technologies, Inc. | Leaflet valve |
US8182528B2 (en) | 2003-12-23 | 2012-05-22 | Sadra Medical, Inc. | Locking heart valve anchor |
US8231670B2 (en) | 2003-12-23 | 2012-07-31 | Sadra Medical, Inc. | Repositionable heart valve and method |
US8236049B2 (en) | 2008-06-20 | 2012-08-07 | Edwards Lifesciences Corporation | Multipiece prosthetic mitral valve and method |
US8246678B2 (en) | 2003-12-23 | 2012-08-21 | Sadra Medicl, Inc. | Methods and apparatus for endovascularly replacing a patient's heart valve |
US8252052B2 (en) | 2003-12-23 | 2012-08-28 | Sadra Medical, Inc. | Methods and apparatus for endovascularly replacing a patient's heart valve |
US8287584B2 (en) | 2005-11-14 | 2012-10-16 | Sadra Medical, Inc. | Medical implant deployment tool |
US8317858B2 (en) | 2008-02-26 | 2012-11-27 | Jenavalve Technology, Inc. | Stent for the positioning and anchoring of a valvular prosthesis in an implantation site in the heart of a patient |
US8328868B2 (en) | 2004-11-05 | 2012-12-11 | Sadra Medical, Inc. | Medical devices and delivery systems for delivering medical devices |
US8343213B2 (en) | 2003-12-23 | 2013-01-01 | Sadra Medical, Inc. | Leaflet engagement elements and methods for use thereof |
WO2012178115A3 (en) * | 2011-06-24 | 2013-02-21 | Rosenbluth, Robert | Percutaneously implantable artificial heart valve system and associated methods and devices |
US8398704B2 (en) | 2008-02-26 | 2013-03-19 | Jenavalve Technology, Inc. | Stent for the positioning and anchoring of a valvular prosthesis in an implantation site in the heart of a patient |
US8465540B2 (en) | 2008-02-26 | 2013-06-18 | Jenavalve Technology, Inc. | Stent for the positioning and anchoring of a valvular prosthesis |
US8468667B2 (en) | 2009-05-15 | 2013-06-25 | Jenavalve Technology, Inc. | Device for compressing a stent |
US8579962B2 (en) | 2003-12-23 | 2013-11-12 | Sadra Medical, Inc. | Methods and apparatus for performing valvuloplasty |
US8603160B2 (en) | 2003-12-23 | 2013-12-10 | Sadra Medical, Inc. | Method of using a retrievable heart valve anchor with a sheath |
US8623076B2 (en) | 2003-12-23 | 2014-01-07 | Sadra Medical, Inc. | Low profile heart valve and delivery system |
CN103517688A (en) * | 2011-01-11 | 2014-01-15 | 汉斯·赖纳·菲古拉 | Valve prosthesis for replacing an atrioventricular valve of the heart |
US8668733B2 (en) | 2004-06-16 | 2014-03-11 | Sadra Medical, Inc. | Everting heart valve |
US8679174B2 (en) | 2005-01-20 | 2014-03-25 | JenaValve Technology, GmbH | Catheter for the transvascular implantation of prosthetic heart valves |
US8728155B2 (en) | 2011-03-21 | 2014-05-20 | Cephea Valve Technologies, Inc. | Disk-based valve apparatus and method for the treatment of valve dysfunction |
US8834561B2 (en) | 2005-10-28 | 2014-09-16 | Jenavalve Technology Gmbh | Device for the implantation and fixation of prosthetic valves |
US8840663B2 (en) | 2003-12-23 | 2014-09-23 | Sadra Medical, Inc. | Repositionable heart valve method |
US8858620B2 (en) | 2003-12-23 | 2014-10-14 | Sadra Medical Inc. | Methods and apparatus for endovascularly replacing a heart valve |
US8870948B1 (en) | 2013-07-17 | 2014-10-28 | Cephea Valve Technologies, Inc. | System and method for cardiac valve repair and replacement |
US8940014B2 (en) | 2011-11-15 | 2015-01-27 | Boston Scientific Scimed, Inc. | Bond between components of a medical device |
US8951243B2 (en) | 2011-12-03 | 2015-02-10 | Boston Scientific Scimed, Inc. | Medical device handle |
US8998976B2 (en) | 2011-07-12 | 2015-04-07 | Boston Scientific Scimed, Inc. | Coupling system for medical devices |
US9005273B2 (en) | 2003-12-23 | 2015-04-14 | Sadra Medical, Inc. | Assessing the location and performance of replacement heart valves |
US9011521B2 (en) | 2003-12-23 | 2015-04-21 | Sadra Medical, Inc. | Methods and apparatus for endovascularly replacing a patient's heart valve |
US9044318B2 (en) | 2008-02-26 | 2015-06-02 | Jenavalve Technology Gmbh | Stent for the positioning and anchoring of a valvular prosthesis |
US9078749B2 (en) | 2007-09-13 | 2015-07-14 | Georg Lutter | Truncated cone heart valve stent |
US9131926B2 (en) | 2011-11-10 | 2015-09-15 | Boston Scientific Scimed, Inc. | Direct connect flush system |
US9168130B2 (en) | 2008-02-26 | 2015-10-27 | Jenavalve Technology Gmbh | Stent for the positioning and anchoring of a valvular prosthesis in an implantation site in the heart of a patient |
US9259237B2 (en) | 2013-07-12 | 2016-02-16 | Inceptus Medical, Llc | Methods and apparatus for treating pulmonary embolism |
US9271832B2 (en) | 2011-05-16 | 2016-03-01 | Hlt, Inc. | Inversion delivery device and method for a prosthesis |
US9277993B2 (en) | 2011-12-20 | 2016-03-08 | Boston Scientific Scimed, Inc. | Medical device delivery systems |
US9289291B2 (en) | 2009-11-05 | 2016-03-22 | The Trustees Of The University Of Pennsylvania | Valve prosthesis |
US9295551B2 (en) | 2007-04-13 | 2016-03-29 | Jenavalve Technology Gmbh | Methods of implanting an endoprosthesis |
US9301840B2 (en) | 2008-10-10 | 2016-04-05 | Edwards Lifesciences Corporation | Expandable introducer sheath |
US9326853B2 (en) | 2010-07-23 | 2016-05-03 | Edwards Lifesciences Corporation | Retaining mechanisms for prosthetic valves |
US9333074B2 (en) | 2009-04-15 | 2016-05-10 | Edwards Lifesciences Cardiaq Llc | Vascular implant and delivery system |
US9339377B2 (en) | 2008-09-29 | 2016-05-17 | Edwards Lifesciences Cardiaq Llc | Body cavity prosthesis |
US9375312B2 (en) | 2010-07-09 | 2016-06-28 | Highlife Sas | Transcatheter atrio-ventricular valve prosthesis |
US9415225B2 (en) | 2005-04-25 | 2016-08-16 | Cardiac Pacemakers, Inc. | Method and apparatus for pacing during revascularization |
US9414918B2 (en) | 2012-09-06 | 2016-08-16 | Edwards Lifesciences Corporation | Heart valve sealing devices |
US9439757B2 (en) | 2014-12-09 | 2016-09-13 | Cephea Valve Technologies, Inc. | Replacement cardiac valves and methods of use and manufacture |
US9439763B2 (en) | 2013-02-04 | 2016-09-13 | Edwards Lifesciences Corporation | Prosthetic valve for replacing mitral valve |
US9480559B2 (en) | 2011-08-11 | 2016-11-01 | Tendyne Holdings, Inc. | Prosthetic valves and related inventions |
US9486314B2 (en) | 2013-03-15 | 2016-11-08 | Hlt, Inc. | Low-profile prosthetic valve structure |
US9486306B2 (en) | 2013-04-02 | 2016-11-08 | Tendyne Holdings, Inc. | Inflatable annular sealing device for prosthetic mitral valve |
US9510947B2 (en) | 2011-10-21 | 2016-12-06 | Jenavalve Technology, Inc. | Catheter system for introducing an expandable heart valve stent into the body of a patient |
US9510945B2 (en) | 2011-12-20 | 2016-12-06 | Boston Scientific Scimed Inc. | Medical device handle |
US9526609B2 (en) | 2003-12-23 | 2016-12-27 | Boston Scientific Scimed, Inc. | Methods and apparatus for endovascularly replacing a patient's heart valve |
US9526611B2 (en) | 2013-10-29 | 2016-12-27 | Tendyne Holdings, Inc. | Apparatus and methods for delivery of transcatheter prosthetic valves |
US9532870B2 (en) | 2014-06-06 | 2017-01-03 | Edwards Lifesciences Corporation | Prosthetic valve for replacing a mitral valve |
US9554897B2 (en) | 2011-04-28 | 2017-01-31 | Neovasc Tiara Inc. | Methods and apparatus for engaging a valve prosthesis with tissue |
US9572665B2 (en) | 2013-04-04 | 2017-02-21 | Neovasc Tiara Inc. | Methods and apparatus for delivering a prosthetic valve to a beating heart |
CN106456325A (en) * | 2014-02-28 | 2017-02-22 | 高品质生活简化股份公司 | Transcatheter valve prosthesis |
US9597182B2 (en) | 2010-05-20 | 2017-03-21 | Jenavalve Technology Inc. | Catheter system for introducing an expandable stent into the body of a patient |
US9597181B2 (en) | 2013-06-25 | 2017-03-21 | Tendyne Holdings, Inc. | Thrombus management and structural compliance features for prosthetic heart valves |
US9597183B2 (en) | 2008-10-01 | 2017-03-21 | Edwards Lifesciences Cardiaq Llc | Delivery system for vascular implant |
US9610159B2 (en) | 2013-05-30 | 2017-04-04 | Tendyne Holdings, Inc. | Structural members for prosthetic mitral valves |
US9675454B2 (en) | 2012-07-30 | 2017-06-13 | Tendyne Holdings, Inc. | Delivery systems and methods for transcatheter prosthetic valves |
US9681951B2 (en) | 2013-03-14 | 2017-06-20 | Edwards Lifesciences Cardiaq Llc | Prosthesis with outer skirt and anchors |
US9713529B2 (en) | 2011-04-28 | 2017-07-25 | Neovasc Tiara Inc. | Sequentially deployed transcatheter mitral valve prosthesis |
US9744031B2 (en) | 2010-05-25 | 2017-08-29 | Jenavalve Technology, Inc. | Prosthetic heart valve and endoprosthesis comprising a prosthetic heart valve and a stent |
US9770329B2 (en) | 2010-05-05 | 2017-09-26 | Neovasc Tiara Inc. | Transcatheter mitral valve prosthesis |
US9788942B2 (en) | 2015-02-03 | 2017-10-17 | Boston Scientific Scimed Inc. | Prosthetic heart valve having tubular seal |
US9801711B2 (en) | 2010-08-11 | 2017-10-31 | Hlt, Inc. | Reinforced commissural support structure |
US20170325938A1 (en) | 2016-05-16 | 2017-11-16 | Boston Scientific Scimed, Inc. | Replacement heart valve implant with invertible leaflets |
US9827095B2 (en) | 2005-05-27 | 2017-11-28 | Hlt, Inc. | Stentless support structure |
US9827092B2 (en) | 2011-12-16 | 2017-11-28 | Tendyne Holdings, Inc. | Tethers for prosthetic mitral valve |
US9839515B2 (en) | 2005-12-22 | 2017-12-12 | Symetis, SA | Stent-valves for valve replacement and associated methods and systems for surgery |
US9861477B2 (en) | 2015-01-26 | 2018-01-09 | Boston Scientific Scimed Inc. | Prosthetic heart valve square leaflet-leaflet stitch |
US9867699B2 (en) | 2008-02-26 | 2018-01-16 | Jenavalve Technology, Inc. | Endoprosthesis for implantation in the heart of a patient |
US9867694B2 (en) | 2013-08-30 | 2018-01-16 | Jenavalve Technology Inc. | Radially collapsible frame for a prosthetic valve and method for manufacturing such a frame |
US9878127B2 (en) | 2012-05-16 | 2018-01-30 | Jenavalve Technology, Inc. | Catheter delivery system for heart valve prosthesis |
US9895221B2 (en) | 2012-07-28 | 2018-02-20 | Tendyne Holdings, Inc. | Multi-component designs for heart valve retrieval device, sealing structures and stent assembly |
US9901445B2 (en) | 2014-11-21 | 2018-02-27 | Boston Scientific Scimed, Inc. | Valve locking mechanism |
US9949816B2 (en) | 2013-06-14 | 2018-04-24 | Avantec Vascular Corporation | IVC filter retrieval systems with multiple capture modes |
US9986993B2 (en) | 2014-02-11 | 2018-06-05 | Tendyne Holdings, Inc. | Adjustable tether and epicardial pad system for prosthetic heart valve |
US9994980B2 (en) | 2016-10-14 | 2018-06-12 | Inceptus Medical, Llc | Braiding machine and methods of use |
US9999504B2 (en) | 2014-10-13 | 2018-06-19 | Hlt, Inc. | Inversion delivery device and method for a prosthesis |
US9999502B2 (en) | 2016-11-04 | 2018-06-19 | Highlife Sas | Transcather valve prosthesis |
US10010417B2 (en) | 2015-04-16 | 2018-07-03 | Edwards Lifesciences Corporation | Low-profile prosthetic heart valve for replacing a mitral valve |
US10016276B2 (en) | 2012-11-21 | 2018-07-10 | Edwards Lifesciences Corporation | Retaining mechanisms for prosthetic heart valves |
US10016275B2 (en) | 2012-05-30 | 2018-07-10 | Neovasc Tiara Inc. | Methods and apparatus for loading a prosthesis onto a delivery system |
US10058424B2 (en) | 2014-08-21 | 2018-08-28 | Edwards Lifesciences Corporation | Dual-flange prosthetic valve frame |
US10064718B2 (en) | 2015-04-16 | 2018-09-04 | Edwards Lifesciences Corporation | Low-profile prosthetic heart valve for replacing a mitral valve |
US10080652B2 (en) | 2015-03-13 | 2018-09-25 | Boston Scientific Scimed, Inc. | Prosthetic heart valve having an improved tubular seal |
US10136991B2 (en) | 2015-08-12 | 2018-11-27 | Boston Scientific Scimed Inc. | Replacement heart valve implant |
US10143552B2 (en) | 2015-05-14 | 2018-12-04 | Cephea Valve Technologies, Inc. | Replacement mitral valves |
US10172708B2 (en) | 2012-01-25 | 2019-01-08 | Boston Scientific Scimed, Inc. | Valve assembly with a bioabsorbable gasket and a replaceable valve implant |
US10179041B2 (en) | 2015-08-12 | 2019-01-15 | Boston Scientific Scimed Icn. | Pinless release mechanism |
US10188514B2 (en) | 2016-11-04 | 2019-01-29 | Highlife Sas | Transcatheter valve prosthesis |
US10195027B2 (en) | 2016-11-04 | 2019-02-05 | Highlife Sas | Transcatheter valve prosthesis |
US10195026B2 (en) | 2014-07-22 | 2019-02-05 | Edwards Lifesciences Corporation | Mitral valve anchoring |
US10195392B2 (en) | 2015-07-02 | 2019-02-05 | Boston Scientific Scimed, Inc. | Clip-on catheter |
US10195028B2 (en) | 2013-09-10 | 2019-02-05 | Edwards Lifesciences Corporation | Magnetic retaining mechanisms for prosthetic valves |
US10201419B2 (en) | 2014-02-05 | 2019-02-12 | Tendyne Holdings, Inc. | Apparatus and methods for transfemoral delivery of prosthetic mitral valve |
US10201417B2 (en) | 2015-02-03 | 2019-02-12 | Boston Scientific Scimed Inc. | Prosthetic heart valve having tubular seal |
US10201418B2 (en) | 2010-09-10 | 2019-02-12 | Symetis, SA | Valve replacement devices, delivery device for a valve replacement device and method of production of a valve replacement device |
US10245136B2 (en) | 2016-05-13 | 2019-04-02 | Boston Scientific Scimed Inc. | Containment vessel with implant sheathing guide |
US10258465B2 (en) | 2003-12-23 | 2019-04-16 | Boston Scientific Scimed Inc. | Methods and apparatus for endovascular heart valve replacement comprising tissue grasping elements |
US10278804B2 (en) | 2014-12-12 | 2019-05-07 | Avantec Vascular Corporation | IVC filter retrieval systems with releasable capture feature |
US10278805B2 (en) | 2000-08-18 | 2019-05-07 | Atritech, Inc. | Expandable implant devices for filtering blood flow from atrial appendages |
US10285809B2 (en) | 2015-03-06 | 2019-05-14 | Boston Scientific Scimed Inc. | TAVI anchoring assist device |
US10327894B2 (en) | 2015-09-18 | 2019-06-25 | Tendyne Holdings, Inc. | Methods for delivery of prosthetic mitral valves |
US10335277B2 (en) | 2015-07-02 | 2019-07-02 | Boston Scientific Scimed Inc. | Adjustable nosecone |
US10342660B2 (en) | 2016-02-02 | 2019-07-09 | Boston Scientific Inc. | Tensioned sheathing aids |
US10368990B2 (en) | 2017-01-23 | 2019-08-06 | Cephea Valve Technologies, Inc. | Replacement mitral valves |
US10376267B2 (en) | 2017-02-24 | 2019-08-13 | Inceptus Medical, Llc | Vascular occlusion devices and methods |
US10376364B2 (en) | 2015-11-10 | 2019-08-13 | Edwards Lifesciences Corporation | Implant delivery capsule |
US10426617B2 (en) | 2015-03-06 | 2019-10-01 | Boston Scientific Scimed, Inc. | Low profile valve locking mechanism and commissure assembly |
US10449043B2 (en) | 2015-01-16 | 2019-10-22 | Boston Scientific Scimed, Inc. | Displacement based lock and release mechanism |
US10456247B2 (en) | 2016-11-04 | 2019-10-29 | Highlife Sas | Transcatheter valve prosthesis |
US10463494B2 (en) | 2013-04-02 | 2019-11-05 | Tendyne Holdings, Inc. | Prosthetic heart valve and systems and methods for delivering the same |
US10463489B2 (en) | 2013-04-02 | 2019-11-05 | Tendyne Holdings, Inc. | Prosthetic heart valve and systems and methods for delivering the same |
US10470881B2 (en) | 2015-05-14 | 2019-11-12 | Cephea Valve Technologies, Inc. | Replacement mitral valves |
US10470877B2 (en) | 2016-05-03 | 2019-11-12 | Tendyne Holdings, Inc. | Apparatus and methods for anterior valve leaflet management |
US10470876B2 (en) | 2015-11-10 | 2019-11-12 | Edwards Lifesciences Corporation | Transcatheter heart valve for replacing natural mitral valve |
US10478293B2 (en) | 2013-04-04 | 2019-11-19 | Tendyne Holdings, Inc. | Retrieval and repositioning system for prosthetic heart valve |
US10517728B2 (en) | 2014-03-10 | 2019-12-31 | Tendyne Holdings, Inc. | Devices and methods for positioning and monitoring tether load for prosthetic mitral valve |
US10555718B2 (en) | 2013-10-17 | 2020-02-11 | Tendyne Holdings, Inc. | Apparatus and methods for alignment and deployment of intracardiac devices |
US10555809B2 (en) | 2012-06-19 | 2020-02-11 | Boston Scientific Scimed, Inc. | Replacement heart valve |
US10583005B2 (en) | 2016-05-13 | 2020-03-10 | Boston Scientific Scimed, Inc. | Medical device handle |
US10583002B2 (en) | 2013-03-11 | 2020-03-10 | Neovasc Tiara Inc. | Prosthetic valve with anti-pivoting mechanism |
US10610356B2 (en) | 2015-02-05 | 2020-04-07 | Tendyne Holdings, Inc. | Expandable epicardial pads and devices and methods for delivery of same |
US10610358B2 (en) | 2015-12-28 | 2020-04-07 | Tendyne Holdings, Inc. | Atrial pocket closures for prosthetic heart valves |
US10610354B2 (en) | 2013-08-01 | 2020-04-07 | Tendyne Holdings, Inc. | Epicardial anchor devices and methods |
US10667905B2 (en) | 2015-04-16 | 2020-06-02 | Tendyne Holdings, Inc. | Apparatus and methods for delivery, repositioning, and retrieval of transcatheter prosthetic valves |
US10709555B2 (en) | 2015-05-01 | 2020-07-14 | Jenavalve Technology, Inc. | Device and method with reduced pacemaker rate in heart valve replacement |
US10736739B2 (en) | 2016-11-04 | 2020-08-11 | Highlife Sas | Transcatheter valve prosthesis |
US10779940B2 (en) | 2015-09-03 | 2020-09-22 | Boston Scientific Scimed, Inc. | Medical device handle |
US10786351B2 (en) | 2015-01-07 | 2020-09-29 | Tendyne Holdings, Inc. | Prosthetic mitral valves and apparatus and methods for delivery of same |
US10828154B2 (en) | 2017-06-08 | 2020-11-10 | Boston Scientific Scimed, Inc. | Heart valve implant commissure support structure |
US10849746B2 (en) | 2015-05-14 | 2020-12-01 | Cephea Valve Technologies, Inc. | Cardiac valve delivery devices and systems |
US10856962B2 (en) | 2014-12-12 | 2020-12-08 | Avantec Vascular Corporation | IVC filter retrieval systems with interposed support members |
US10874499B2 (en) | 2016-12-22 | 2020-12-29 | Avantec Vascular Corporation | Systems, devices, and methods for retrieval systems having a tether |
US10898325B2 (en) | 2017-08-01 | 2021-01-26 | Boston Scientific Scimed, Inc. | Medical implant locking mechanism |
US10939996B2 (en) | 2017-08-16 | 2021-03-09 | Boston Scientific Scimed, Inc. | Replacement heart valve commissure assembly |
US11039921B2 (en) | 2016-06-13 | 2021-06-22 | Tendyne Holdings, Inc. | Sequential delivery of two-part prosthetic mitral valve |
US11065138B2 (en) | 2016-05-13 | 2021-07-20 | Jenavalve Technology, Inc. | Heart valve prosthesis delivery system and method for delivery of heart valve prosthesis with introducer sheath and loading system |
US11065116B2 (en) | 2016-07-12 | 2021-07-20 | Tendyne Holdings, Inc. | Apparatus and methods for trans-septal retrieval of prosthetic heart valves |
US11090157B2 (en) | 2016-06-30 | 2021-08-17 | Tendyne Holdings, Inc. | Prosthetic heart valves and apparatus and methods for delivery of same |
US11096782B2 (en) | 2015-12-03 | 2021-08-24 | Tendyne Holdings, Inc. | Frame features for prosthetic mitral valves |
US11147668B2 (en) | 2018-02-07 | 2021-10-19 | Boston Scientific Scimed, Inc. | Medical device delivery system with alignment feature |
US11154399B2 (en) | 2017-07-13 | 2021-10-26 | Tendyne Holdings, Inc. | Prosthetic heart valves and apparatus and methods for delivery of same |
US11179236B2 (en) | 2009-12-08 | 2021-11-23 | Colorado State University Research Foundation | Device and system for transcatheter mitral valve replacement |
US11191639B2 (en) | 2017-08-28 | 2021-12-07 | Tendyne Holdings, Inc. | Prosthetic heart valves with tether coupling features |
US11191641B2 (en) | 2018-01-19 | 2021-12-07 | Boston Scientific Scimed, Inc. | Inductance mode deployment sensors for transcatheter valve system |
US11197754B2 (en) | 2017-01-27 | 2021-12-14 | Jenavalve Technology, Inc. | Heart valve mimicry |
US11224510B2 (en) | 2013-04-02 | 2022-01-18 | Tendyne Holdings, Inc. | Prosthetic heart valve and systems and methods for delivering the same |
US11229517B2 (en) | 2018-05-15 | 2022-01-25 | Boston Scientific Scimed, Inc. | Replacement heart valve commissure assembly |
US11241312B2 (en) | 2018-12-10 | 2022-02-08 | Boston Scientific Scimed, Inc. | Medical device delivery system including a resistance member |
US11241310B2 (en) | 2018-06-13 | 2022-02-08 | Boston Scientific Scimed, Inc. | Replacement heart valve delivery device |
US11246625B2 (en) | 2018-01-19 | 2022-02-15 | Boston Scientific Scimed, Inc. | Medical device delivery system with feedback loop |
US11278406B2 (en) | 2010-05-20 | 2022-03-22 | Jenavalve Technology, Inc. | Catheter system for introducing an expandable heart valve stent into the body of a patient, insertion system with a catheter system and medical device for treatment of a heart valve defect |
US11278398B2 (en) | 2003-12-23 | 2022-03-22 | Boston Scientific Scimed, Inc. | Methods and apparatus for endovascular heart valve replacement comprising tissue grasping elements |
US11285002B2 (en) | 2003-12-23 | 2022-03-29 | Boston Scientific Scimed, Inc. | Methods and apparatus for endovascularly replacing a heart valve |
US11331187B2 (en) | 2016-06-17 | 2022-05-17 | Cephea Valve Technologies, Inc. | Cardiac valve delivery devices and systems |
US11364030B2 (en) * | 2019-02-15 | 2022-06-21 | Boston Scientific Scimed, Inc. | Medical device for treating esophageal atresia |
US11439732B2 (en) | 2018-02-26 | 2022-09-13 | Boston Scientific Scimed, Inc. | Embedded radiopaque marker in adaptive seal |
US11439504B2 (en) | 2019-05-10 | 2022-09-13 | Boston Scientific Scimed, Inc. | Replacement heart valve with improved cusp washout and reduced loading |
US11648114B2 (en) | 2019-12-20 | 2023-05-16 | Tendyne Holdings, Inc. | Distally loaded sheath and loading funnel |
US11648110B2 (en) | 2019-12-05 | 2023-05-16 | Tendyne Holdings, Inc. | Braided anchor for mitral valve |
US11678980B2 (en) | 2020-08-19 | 2023-06-20 | Tendyne Holdings, Inc. | Fully-transseptal apical pad with pulley for tensioning |
US11771544B2 (en) | 2011-05-05 | 2023-10-03 | Symetis Sa | Method and apparatus for compressing/loading stent-valves |
US11833025B2 (en) | 2018-06-29 | 2023-12-05 | Avantec Vascular Corporation | Systems and methods for implants and deployment devices |
US11885051B2 (en) | 2017-10-14 | 2024-01-30 | Inceptus Medical, Llc | Braiding machine and methods of use |
US11951002B2 (en) | 2020-03-30 | 2024-04-09 | Tendyne Holdings, Inc. | Apparatus and methods for valve and tether fixation |
Families Citing this family (315)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE10010074B4 (en) | 2000-02-28 | 2005-04-14 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Device for fastening and anchoring heart valve prostheses |
DE10010073B4 (en) | 2000-02-28 | 2005-12-22 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Anchoring for implantable heart valve prostheses |
US8366769B2 (en) | 2000-06-01 | 2013-02-05 | Edwards Lifesciences Corporation | Low-profile, pivotable heart valve sewing ring |
US6409758B2 (en) | 2000-07-27 | 2002-06-25 | Edwards Lifesciences Corporation | Heart valve holder for constricting the valve commissures and methods of use |
FR2828263B1 (en) | 2001-08-03 | 2007-05-11 | Philipp Bonhoeffer | DEVICE FOR IMPLANTATION OF AN IMPLANT AND METHOD FOR IMPLANTATION OF THE DEVICE |
AU2002337598A1 (en) | 2001-10-04 | 2003-04-14 | Neovasc Medical Ltd. | Flow reducing implant |
US7201771B2 (en) | 2001-12-27 | 2007-04-10 | Arbor Surgical Technologies, Inc. | Bioprosthetic heart valve |
US7959674B2 (en) | 2002-07-16 | 2011-06-14 | Medtronic, Inc. | Suture locking assembly and method of use |
US8551162B2 (en) | 2002-12-20 | 2013-10-08 | Medtronic, Inc. | Biologically implantable prosthesis |
US8021421B2 (en) | 2003-08-22 | 2011-09-20 | Medtronic, Inc. | Prosthesis heart valve fixturing device |
US7556647B2 (en) | 2003-10-08 | 2009-07-07 | Arbor Surgical Technologies, Inc. | Attachment device and methods of using the same |
IL158960A0 (en) | 2003-11-19 | 2004-05-12 | Neovasc Medical Ltd | Vascular implant |
US7871435B2 (en) | 2004-01-23 | 2011-01-18 | Edwards Lifesciences Corporation | Anatomically approximate prosthetic mitral heart valve |
EP2308425B2 (en) | 2004-03-11 | 2023-10-18 | Percutaneous Cardiovascular Solutions Pty Limited | Percutaneous Heart Valve Prosthesis |
US7534259B2 (en) | 2004-05-05 | 2009-05-19 | Direct Flow Medical, Inc. | Nonstented heart valves with formed in situ support |
US8574257B2 (en) | 2005-02-10 | 2013-11-05 | Edwards Lifesciences Corporation | System, device, and method for providing access in a cardiovascular environment |
WO2006097931A2 (en) | 2005-03-17 | 2006-09-21 | Valtech Cardio, Ltd. | Mitral valve treatment techniques |
US7513909B2 (en) | 2005-04-08 | 2009-04-07 | Arbor Surgical Technologies, Inc. | Two-piece prosthetic valves with snap-in connection and methods for use |
US7799072B2 (en) * | 2005-05-20 | 2010-09-21 | The Cleveland Clinic Foundation | Apparatus and methods for repairing the function of a diseased valve and method for making same |
EP1883375B1 (en) | 2005-05-24 | 2016-12-07 | Edwards Lifesciences Corporation | Rapid deployment prosthetic heart valve |
US8211169B2 (en) | 2005-05-27 | 2012-07-03 | Medtronic, Inc. | Gasket with collar for prosthetic heart valves and methods for using them |
WO2006133294A2 (en) | 2005-06-07 | 2006-12-14 | Direct Flow Medical, Inc. | Stentless aortic valve replacement with high radial strength |
US8951285B2 (en) | 2005-07-05 | 2015-02-10 | Mitralign, Inc. | Tissue anchor, anchoring system and methods of using the same |
US7776084B2 (en) | 2005-07-13 | 2010-08-17 | Edwards Lifesciences Corporation | Prosthetic mitral heart valve having a contoured sewing ring |
DE102005052628B4 (en) | 2005-11-04 | 2014-06-05 | Jenavalve Technology Inc. | Self-expanding, flexible wire mesh with integrated valvular prosthesis for the transvascular heart valve replacement and a system with such a device and a delivery catheter |
WO2007058857A2 (en) | 2005-11-10 | 2007-05-24 | Arshad Quadri | Balloon-expandable, self-expanding, vascular prosthesis connecting stent |
US7967857B2 (en) | 2006-01-27 | 2011-06-28 | Medtronic, Inc. | Gasket with spring collar for prosthetic heart valves and methods for making and using them |
WO2007130881A2 (en) | 2006-04-29 | 2007-11-15 | Arbor Surgical Technologies, Inc. | Multiple component prosthetic heart valve assemblies and apparatus and methods for delivering them |
US8021161B2 (en) | 2006-05-01 | 2011-09-20 | Edwards Lifesciences Corporation | Simulated heart valve root for training and testing |
WO2008013915A2 (en) | 2006-07-28 | 2008-01-31 | Arshad Quadri | Percutaneous valve prosthesis and system and method for implanting same |
US8252036B2 (en) | 2006-07-31 | 2012-08-28 | Syntheon Cardiology, Llc | Sealable endovascular implants and methods for their use |
US9585743B2 (en) * | 2006-07-31 | 2017-03-07 | Edwards Lifesciences Cardiaq Llc | Surgical implant devices and methods for their manufacture and use |
US9408607B2 (en) | 2009-07-02 | 2016-08-09 | Edwards Lifesciences Cardiaq Llc | Surgical implant devices and methods for their manufacture and use |
FR2906454B1 (en) * | 2006-09-28 | 2009-04-10 | Perouse Soc Par Actions Simpli | IMPLANT INTENDED TO BE PLACED IN A BLOOD CIRCULATION CONDUIT. |
US7935144B2 (en) | 2006-10-19 | 2011-05-03 | Direct Flow Medical, Inc. | Profile reduction of valve implant |
US8133213B2 (en) | 2006-10-19 | 2012-03-13 | Direct Flow Medical, Inc. | Catheter guidance through a calcified aortic valve |
US11259924B2 (en) | 2006-12-05 | 2022-03-01 | Valtech Cardio Ltd. | Implantation of repair devices in the heart |
US9883943B2 (en) | 2006-12-05 | 2018-02-06 | Valtech Cardio, Ltd. | Implantation of repair devices in the heart |
US11660190B2 (en) | 2007-03-13 | 2023-05-30 | Edwards Lifesciences Corporation | Tissue anchors, systems and methods, and devices |
US9138315B2 (en) | 2007-04-13 | 2015-09-22 | Jenavalve Technology Gmbh | Medical device for treating a heart valve insufficiency or stenosis |
JP5264264B2 (en) * | 2007-04-23 | 2013-08-14 | セント ジョセフズ トランスレーショナル リサーチ インスティテュート インコーポレイテッド | Replacement heart valve and method of manufacturing the same |
US20110022149A1 (en) | 2007-06-04 | 2011-01-27 | Cox Brian J | Methods and devices for treatment of vascular defects |
US9814611B2 (en) | 2007-07-31 | 2017-11-14 | Edwards Lifesciences Cardiaq Llc | Actively controllable stent, stent graft, heart valve and method of controlling same |
US9566178B2 (en) | 2010-06-24 | 2017-02-14 | Edwards Lifesciences Cardiaq Llc | Actively controllable stent, stent graft, heart valve and method of controlling same |
CA2978267A1 (en) | 2007-08-23 | 2009-02-23 | Dfm, Llc | Translumenally implantable heart valve with formed in place support |
AU2008305600B2 (en) | 2007-09-26 | 2013-07-04 | St. Jude Medical, Inc. | Collapsible prosthetic heart valves |
US9532868B2 (en) | 2007-09-28 | 2017-01-03 | St. Jude Medical, Inc. | Collapsible-expandable prosthetic heart valves with structures for clamping native tissue |
EP2244668A1 (en) * | 2008-01-25 | 2010-11-03 | JenaValve Technology Inc. | Medical apparatus for the therapeutic treatment of an insufficient cardiac valve |
US8801776B2 (en) † | 2008-02-25 | 2014-08-12 | Medtronic Vascular, Inc. | Infundibular reducer devices |
US8382829B1 (en) | 2008-03-10 | 2013-02-26 | Mitralign, Inc. | Method to reduce mitral regurgitation by cinching the commissure of the mitral valve |
US20090276040A1 (en) | 2008-05-01 | 2009-11-05 | Edwards Lifesciences Corporation | Device and method for replacing mitral valve |
BRPI0911923B8 (en) | 2008-05-02 | 2021-06-22 | Sequent Medical Inc | device for treating a cerebral aneurysm |
US9226820B2 (en) * | 2008-07-15 | 2016-01-05 | St. Jude Medical, Inc. | Axially anchoring collapsible and re-expandable prosthetic heart valves for various disease states |
DE202009019058U1 (en) | 2008-07-15 | 2016-01-26 | St. Jude Medical, Inc. | Heart valve prosthesis and arrangement for delivering a heart valve prosthesis |
US8449625B2 (en) | 2009-10-27 | 2013-05-28 | Edwards Lifesciences Corporation | Methods of measuring heart valve annuluses for valve replacement |
WO2010065265A2 (en) | 2008-11-25 | 2010-06-10 | Edwards Lifesciences Corporation | Apparatus and method for in situ expansion of prosthetic device |
US8308798B2 (en) | 2008-12-19 | 2012-11-13 | Edwards Lifesciences Corporation | Quick-connect prosthetic heart valve and methods |
US8545553B2 (en) | 2009-05-04 | 2013-10-01 | Valtech Cardio, Ltd. | Over-wire rotation tool |
US8926696B2 (en) | 2008-12-22 | 2015-01-06 | Valtech Cardio, Ltd. | Adjustable annuloplasty devices and adjustment mechanisms therefor |
US8715342B2 (en) | 2009-05-07 | 2014-05-06 | Valtech Cardio, Ltd. | Annuloplasty ring with intra-ring anchoring |
US10517719B2 (en) | 2008-12-22 | 2019-12-31 | Valtech Cardio, Ltd. | Implantation of repair devices in the heart |
US8241351B2 (en) | 2008-12-22 | 2012-08-14 | Valtech Cardio, Ltd. | Adjustable partial annuloplasty ring and mechanism therefor |
US8353956B2 (en) | 2009-02-17 | 2013-01-15 | Valtech Cardio, Ltd. | Actively-engageable movement-restriction mechanism for use with an annuloplasty structure |
US8348997B2 (en) | 2009-02-24 | 2013-01-08 | Medtronic Vascular, Inc. | One-way replacement valve |
US20100217382A1 (en) * | 2009-02-25 | 2010-08-26 | Edwards Lifesciences | Mitral valve replacement with atrial anchoring |
AU2010218384B2 (en) | 2009-02-27 | 2014-11-20 | St. Jude Medical, Inc. | Stent features for collapsible prosthetic heart valves |
US9980818B2 (en) | 2009-03-31 | 2018-05-29 | Edwards Lifesciences Corporation | Prosthetic heart valve system with positioning markers |
US9968452B2 (en) | 2009-05-04 | 2018-05-15 | Valtech Cardio, Ltd. | Annuloplasty ring delivery cathethers |
WO2010132451A2 (en) | 2009-05-11 | 2010-11-18 | Mayo Foundation For Medical Education And Research | Treating congestive heart failure |
US8348998B2 (en) | 2009-06-26 | 2013-01-08 | Edwards Lifesciences Corporation | Unitary quick connect prosthetic heart valve and deployment system and methods |
US9730790B2 (en) | 2009-09-29 | 2017-08-15 | Edwards Lifesciences Cardiaq Llc | Replacement valve and method |
US10098737B2 (en) | 2009-10-29 | 2018-10-16 | Valtech Cardio, Ltd. | Tissue anchor for annuloplasty device |
US9180007B2 (en) | 2009-10-29 | 2015-11-10 | Valtech Cardio, Ltd. | Apparatus and method for guide-wire based advancement of an adjustable implant |
CA2778639A1 (en) | 2009-11-05 | 2011-05-12 | Sequent Medical Inc. | Multiple layer filamentary devices or treatment of vascular defects |
EP2506777B1 (en) | 2009-12-02 | 2020-11-25 | Valtech Cardio, Ltd. | Combination of spool assembly coupled to a helical anchor and delivery tool for implantation thereof |
US8870950B2 (en) | 2009-12-08 | 2014-10-28 | Mitral Tech Ltd. | Rotation-based anchoring of an implant |
WO2011111047A2 (en) | 2010-03-10 | 2011-09-15 | Mitraltech Ltd. | Prosthetic mitral valve with tissue anchors |
US8986374B2 (en) | 2010-05-10 | 2015-03-24 | Edwards Lifesciences Corporation | Prosthetic heart valve |
US9554901B2 (en) | 2010-05-12 | 2017-01-31 | Edwards Lifesciences Corporation | Low gradient prosthetic heart valve |
AU2011271007A1 (en) | 2010-06-21 | 2013-01-31 | Cardiaq Valve Technologies, Inc. | Replacement heart valve |
US20110313359A1 (en) * | 2010-06-21 | 2011-12-22 | Cohen Stanley A | Retention device for gastrostomy tube and low profile gastrostomy device |
US11653910B2 (en) | 2010-07-21 | 2023-05-23 | Cardiovalve Ltd. | Helical anchor implantation |
US8992604B2 (en) | 2010-07-21 | 2015-03-31 | Mitraltech Ltd. | Techniques for percutaneous mitral valve replacement and sealing |
US9763657B2 (en) | 2010-07-21 | 2017-09-19 | Mitraltech Ltd. | Techniques for percutaneous mitral valve replacement and sealing |
US9132009B2 (en) | 2010-07-21 | 2015-09-15 | Mitraltech Ltd. | Guide wires with commissural anchors to advance a prosthetic valve |
US9125741B2 (en) | 2010-09-10 | 2015-09-08 | Edwards Lifesciences Corporation | Systems and methods for ensuring safe and rapid deployment of prosthetic heart valves |
US9370418B2 (en) | 2010-09-10 | 2016-06-21 | Edwards Lifesciences Corporation | Rapidly deployable surgical heart valves |
US8641757B2 (en) | 2010-09-10 | 2014-02-04 | Edwards Lifesciences Corporation | Systems for rapidly deploying surgical heart valves |
US9579193B2 (en) | 2010-09-23 | 2017-02-28 | Transmural Systems Llc | Methods and systems for delivering prostheses using rail techniques |
EP3459500B1 (en) | 2010-09-23 | 2020-09-16 | Edwards Lifesciences CardiAQ LLC | Replacement heart valves and delivery devices |
US10321998B2 (en) | 2010-09-23 | 2019-06-18 | Transmural Systems Llc | Methods and systems for delivering prostheses using rail techniques |
US8845720B2 (en) | 2010-09-27 | 2014-09-30 | Edwards Lifesciences Corporation | Prosthetic heart valve frame with flexible commissures |
CA3035048C (en) | 2010-12-23 | 2021-05-04 | Mark Deem | System for mitral valve repair and replacement |
EP2663258B1 (en) | 2011-01-11 | 2018-11-21 | Hans Reiner Figulla | Prosthetic valve for replacing an atrioventricular heart valve |
US8888843B2 (en) | 2011-01-28 | 2014-11-18 | Middle Peak Medical, Inc. | Device, system, and method for transcatheter treatment of valve regurgitation |
US8845717B2 (en) | 2011-01-28 | 2014-09-30 | Middle Park Medical, Inc. | Coaptation enhancement implant, system, and method |
US8945209B2 (en) | 2011-05-20 | 2015-02-03 | Edwards Lifesciences Corporation | Encapsulated heart valve |
AU2012272855C1 (en) | 2011-06-21 | 2018-04-05 | Twelve, Inc. | Prosthetic heart valve devices and associated systems and methods |
US10792152B2 (en) | 2011-06-23 | 2020-10-06 | Valtech Cardio, Ltd. | Closed band for percutaneous annuloplasty |
US9918840B2 (en) | 2011-06-23 | 2018-03-20 | Valtech Cardio, Ltd. | Closed band for percutaneous annuloplasty |
US20140324164A1 (en) | 2011-08-05 | 2014-10-30 | Mitraltech Ltd. | Techniques for percutaneous mitral valve replacement and sealing |
WO2013021374A2 (en) | 2011-08-05 | 2013-02-14 | Mitraltech Ltd. | Techniques for percutaneous mitral valve replacement and sealing |
US8852272B2 (en) | 2011-08-05 | 2014-10-07 | Mitraltech Ltd. | Techniques for percutaneous mitral valve replacement and sealing |
EP2739214B1 (en) | 2011-08-05 | 2018-10-10 | Cardiovalve Ltd | Percutaneous mitral valve replacement and sealing |
DE102011054172A1 (en) * | 2011-09-12 | 2013-03-14 | Highlife Sas | Transcatheter valve prosthesis |
US9387075B2 (en) | 2011-09-12 | 2016-07-12 | Highlife Sas | Transcatheter valve prosthesis |
CN103917194B (en) | 2011-09-12 | 2017-02-15 | 高品质生活简化股份公司 | Transcatheter valve prosthesis |
US8956404B2 (en) | 2011-09-12 | 2015-02-17 | Highlife Sas | Transcatheter valve prosthesis |
US9549817B2 (en) | 2011-09-22 | 2017-01-24 | Transmural Systems Llc | Devices, systems and methods for repairing lumenal systems |
US9039757B2 (en) | 2011-10-19 | 2015-05-26 | Twelve, Inc. | Prosthetic heart valve devices, prosthetic mitral valves and associated systems and methods |
EP2750630B1 (en) | 2011-10-19 | 2021-06-30 | Twelve, Inc. | Device for heart valve replacement |
US9655722B2 (en) | 2011-10-19 | 2017-05-23 | Twelve, Inc. | Prosthetic heart valve devices, prosthetic mitral valves and associated systems and methods |
US9763780B2 (en) * | 2011-10-19 | 2017-09-19 | Twelve, Inc. | Devices, systems and methods for heart valve replacement |
US11202704B2 (en) | 2011-10-19 | 2021-12-21 | Twelve, Inc. | Prosthetic heart valve devices, prosthetic mitral valves and associated systems and methods |
US10016271B2 (en) | 2011-10-19 | 2018-07-10 | Twelve, Inc. | Prosthetic heart valve devices, prosthetic mitral valves and associated systems and methods |
US9827093B2 (en) | 2011-10-21 | 2017-11-28 | Edwards Lifesciences Cardiaq Llc | Actively controllable stent, stent graft, heart valve and method of controlling same |
US8858623B2 (en) | 2011-11-04 | 2014-10-14 | Valtech Cardio, Ltd. | Implant having multiple rotational assemblies |
US9724192B2 (en) | 2011-11-08 | 2017-08-08 | Valtech Cardio, Ltd. | Controlled steering functionality for implant-delivery tool |
EP2793765B1 (en) * | 2011-12-19 | 2021-02-17 | Coloplast A/S | A luminal prosthesis |
US9078747B2 (en) | 2011-12-21 | 2015-07-14 | Edwards Lifesciences Corporation | Anchoring device for replacing or repairing a heart valve |
EP2620125B1 (en) | 2012-01-24 | 2017-10-11 | Medtentia International Ltd Oy | An arrangement, a loop-shaped support, a prosthetic heart valve and a method of repairing or replacing a native heart valve |
US9579198B2 (en) | 2012-03-01 | 2017-02-28 | Twelve, Inc. | Hydraulic delivery systems for prosthetic heart valve devices and associated methods |
GB2500432A (en) * | 2012-03-22 | 2013-09-25 | Stephen Brecker | Replacement heart valve with resiliently deformable securing means |
US9011515B2 (en) | 2012-04-19 | 2015-04-21 | Caisson Interventional, LLC | Heart valve assembly systems and methods |
US9427315B2 (en) | 2012-04-19 | 2016-08-30 | Caisson Interventional, LLC | Valve replacement systems and methods |
DE102012107465A1 (en) * | 2012-08-15 | 2014-05-22 | Pfm Medical Ag | Implantable device for use in the human and / or animal body for replacement of an organ flap |
EP2900150B1 (en) | 2012-09-29 | 2018-04-18 | Mitralign, Inc. | Plication lock delivery system |
US10376266B2 (en) | 2012-10-23 | 2019-08-13 | Valtech Cardio, Ltd. | Percutaneous tissue anchor techniques |
US9949828B2 (en) | 2012-10-23 | 2018-04-24 | Valtech Cardio, Ltd. | Controlled steering functionality for implant-delivery tool |
US8628571B1 (en) | 2012-11-13 | 2014-01-14 | Mitraltech Ltd. | Percutaneously-deliverable mechanical valve |
WO2014087402A1 (en) | 2012-12-06 | 2014-06-12 | Valtech Cardio, Ltd. | Techniques for guide-wire based advancement of a tool |
EP2742911A1 (en) | 2012-12-17 | 2014-06-18 | Hans Reiner Figulla | Valve prosthesis for replacing an atrioventricular valve |
EP2948103B1 (en) | 2013-01-24 | 2022-12-07 | Cardiovalve Ltd | Ventricularly-anchored prosthetic valves |
WO2014134183A1 (en) | 2013-02-26 | 2014-09-04 | Mitralign, Inc. | Devices and methods for percutaneous tricuspid valve repair |
US20140243954A1 (en) * | 2013-02-27 | 2014-08-28 | Donald Shannon | Transcatheter mitral valve prosthesis |
US9398951B2 (en) | 2013-03-12 | 2016-07-26 | St. Jude Medical, Cardiology Division, Inc. | Self-actuating sealing portions for paravalvular leak protection |
US9339274B2 (en) | 2013-03-12 | 2016-05-17 | St. Jude Medical, Cardiology Division, Inc. | Paravalvular leak occlusion device for self-expanding heart valves |
US8986375B2 (en) * | 2013-03-12 | 2015-03-24 | Medtronic, Inc. | Anti-paravalvular leakage component for a transcatheter valve prosthesis |
EP2967849A4 (en) | 2013-03-12 | 2017-01-18 | St. Jude Medical, Cardiology Division, Inc. | Self-actuating sealing portions for paravalvular leak protection |
US10271949B2 (en) | 2013-03-12 | 2019-04-30 | St. Jude Medical, Cardiology Division, Inc. | Paravalvular leak occlusion device for self-expanding heart valves |
US10449333B2 (en) | 2013-03-14 | 2019-10-22 | Valtech Cardio, Ltd. | Guidewire feeder |
US9730791B2 (en) | 2013-03-14 | 2017-08-15 | Edwards Lifesciences Cardiaq Llc | Prosthesis for atraumatically grasping intralumenal tissue and methods of delivery |
US20140277427A1 (en) | 2013-03-14 | 2014-09-18 | Cardiaq Valve Technologies, Inc. | Prosthesis for atraumatically grasping intralumenal tissue and methods of delivery |
US9326856B2 (en) | 2013-03-14 | 2016-05-03 | St. Jude Medical, Cardiology Division, Inc. | Cuff configurations for prosthetic heart valve |
CN105283214B (en) | 2013-03-15 | 2018-10-16 | 北京泰德制药股份有限公司 | Translate conduit, system and its application method |
US11007058B2 (en) | 2013-03-15 | 2021-05-18 | Edwards Lifesciences Corporation | Valved aortic conduits |
CA2900367C (en) | 2013-03-15 | 2020-12-22 | Edwards Lifesciences Corporation | Valved aortic conduits |
CN108294846A (en) | 2013-05-20 | 2018-07-20 | 托尔福公司 | Implantable cardiac valve device, mitral valve repair device and related system and method |
US9468527B2 (en) | 2013-06-12 | 2016-10-18 | Edwards Lifesciences Corporation | Cardiac implant with integrated suture fasteners |
US10321991B2 (en) | 2013-06-19 | 2019-06-18 | St. Jude Medical, Cardiology Division, Inc. | Collapsible valve having paravalvular leak protection |
US9955976B2 (en) | 2013-08-16 | 2018-05-01 | Sequent Medical, Inc. | Filamentary devices for treatment of vascular defects |
US9078658B2 (en) | 2013-08-16 | 2015-07-14 | Sequent Medical, Inc. | Filamentary devices for treatment of vascular defects |
US9919137B2 (en) | 2013-08-28 | 2018-03-20 | Edwards Lifesciences Corporation | Integrated balloon catheter inflation system |
US10070857B2 (en) | 2013-08-31 | 2018-09-11 | Mitralign, Inc. | Devices and methods for locating and implanting tissue anchors at mitral valve commissure |
US10117742B2 (en) | 2013-09-12 | 2018-11-06 | St. Jude Medical, Cardiology Division, Inc. | Stent designs for prosthetic heart valves |
EP3046512B1 (en) | 2013-09-20 | 2024-03-06 | Edwards Lifesciences Corporation | Heart valves with increased effective orifice area |
SG11201601674WA (en) * | 2013-10-05 | 2016-04-28 | Sino Medical Sciences Tech Inc | Device and method for mitral valve regurgitation method |
US10299793B2 (en) | 2013-10-23 | 2019-05-28 | Valtech Cardio, Ltd. | Anchor magazine |
US9050188B2 (en) | 2013-10-23 | 2015-06-09 | Caisson Interventional, LLC | Methods and systems for heart valve therapy |
US10166098B2 (en) | 2013-10-25 | 2019-01-01 | Middle Peak Medical, Inc. | Systems and methods for transcatheter treatment of valve regurgitation |
US9913715B2 (en) | 2013-11-06 | 2018-03-13 | St. Jude Medical, Cardiology Division, Inc. | Paravalvular leak sealing mechanism |
US20150122687A1 (en) | 2013-11-06 | 2015-05-07 | Edwards Lifesciences Corporation | Bioprosthetic heart valves having adaptive seals to minimize paravalvular leakage |
US9700409B2 (en) | 2013-11-06 | 2017-07-11 | St. Jude Medical, Cardiology Division, Inc. | Reduced profile prosthetic heart valve |
EP2870946B1 (en) | 2013-11-06 | 2018-10-31 | St. Jude Medical, Cardiology Division, Inc. | Paravalvular leak sealing mechanism |
EP3071149B1 (en) | 2013-11-19 | 2022-06-01 | St. Jude Medical, Cardiology Division, Inc. | Sealing structures for paravalvular leak protection |
US9610162B2 (en) | 2013-12-26 | 2017-04-04 | Valtech Cardio, Ltd. | Implantation of flexible implant |
EP2896387A1 (en) * | 2014-01-20 | 2015-07-22 | Mitricares | Heart valve anchoring device |
US20150209141A1 (en) | 2014-01-24 | 2015-07-30 | St. Jude Medical, Cardiology Division, Inc. | Stationary intra-annular halo designs for paravalvular leak (pvl) reduction-passive channel filling cuff designs |
US9820852B2 (en) | 2014-01-24 | 2017-11-21 | St. Jude Medical, Cardiology Division, Inc. | Stationary intra-annular halo designs for paravalvular leak (PVL) reduction—active channel filling cuff designs |
EP3107496B1 (en) | 2014-02-18 | 2018-07-04 | St. Jude Medical, Cardiology Division, Inc. | Bowed runners for paravalvular leak protection |
EP3107497B1 (en) | 2014-02-21 | 2020-07-22 | Edwards Lifesciences CardiAQ LLC | Delivery device for controlled deployment of a replacement valve |
US9763779B2 (en) | 2014-03-11 | 2017-09-19 | Highlife Sas | Transcatheter valve prosthesis |
US10064719B2 (en) | 2014-03-11 | 2018-09-04 | Highlife Sas | Transcatheter valve prosthesis |
US9889003B2 (en) | 2014-03-11 | 2018-02-13 | Highlife Sas | Transcatheter valve prosthesis |
USD755384S1 (en) | 2014-03-05 | 2016-05-03 | Edwards Lifesciences Cardiaq Llc | Stent |
US9687343B2 (en) | 2014-03-11 | 2017-06-27 | Highlife Sas | Transcatheter valve prosthesis |
JP6526043B2 (en) | 2014-03-26 | 2019-06-05 | セント・ジュード・メディカル,カーディオロジー・ディヴィジョン,インコーポレイテッド | Transcatheter mitral valve stent frame |
US10058315B2 (en) | 2014-03-27 | 2018-08-28 | Transmural Systems Llc | Devices and methods for closure of transvascular or transcameral access ports |
EP3125826B1 (en) | 2014-03-31 | 2020-10-07 | St. Jude Medical, Cardiology Division, Inc. | Paravalvular sealing via extended cuff mechanisms |
US9549816B2 (en) | 2014-04-03 | 2017-01-24 | Edwards Lifesciences Corporation | Method for manufacturing high durability heart valve |
US9629635B2 (en) | 2014-04-14 | 2017-04-25 | Sequent Medical, Inc. | Devices for therapeutic vascular procedures |
US9585752B2 (en) | 2014-04-30 | 2017-03-07 | Edwards Lifesciences Corporation | Holder and deployment system for surgical heart valves |
ES2795358T3 (en) | 2014-05-16 | 2020-11-23 | St Jude Medical Cardiology Div Inc | Subannular sealing for paravalvular leak protection |
EP3142604B1 (en) | 2014-05-16 | 2024-01-10 | St. Jude Medical, Cardiology Division, Inc. | Transcatheter valve with paravalvular leak sealing ring |
EP3257473A1 (en) | 2014-05-16 | 2017-12-20 | St. Jude Medical, Cardiology Division, Inc. | Stent assembly for use in prosthetic heart valves |
EP3128952A1 (en) | 2014-05-19 | 2017-02-15 | Edwards Lifesciences CardiAQ LLC | Replacement mitral valve with annular flap |
EP3145450B1 (en) | 2014-05-22 | 2019-07-17 | St. Jude Medical, Cardiology Division, Inc. | Stents with anchoring sections |
US9974647B2 (en) | 2014-06-12 | 2018-05-22 | Caisson Interventional, LLC | Two stage anchor and mitral valve assembly |
ES2908178T3 (en) | 2014-06-18 | 2022-04-28 | Polares Medical Inc | Mitral valve implants for the treatment of valvular regurgitation |
CA2914094C (en) | 2014-06-20 | 2021-01-05 | Edwards Lifesciences Corporation | Surgical heart valves identifiable post-implant |
USD867594S1 (en) | 2015-06-19 | 2019-11-19 | Edwards Lifesciences Corporation | Prosthetic heart valve |
ES2914153T3 (en) | 2014-06-24 | 2022-06-07 | Polares Medical Inc | Systems to anchor an implant |
WO2016016899A1 (en) | 2014-07-30 | 2016-02-04 | Mitraltech Ltd. | Articulatable prosthetic valve |
EP4331503A2 (en) | 2014-10-14 | 2024-03-06 | Edwards Lifesciences Innovation (Israel) Ltd. | Leaflet-restraining techniques |
US9750605B2 (en) | 2014-10-23 | 2017-09-05 | Caisson Interventional, LLC | Systems and methods for heart valve therapy |
US9750607B2 (en) | 2014-10-23 | 2017-09-05 | Caisson Interventional, LLC | Systems and methods for heart valve therapy |
WO2016083551A1 (en) * | 2014-11-26 | 2016-06-02 | Konstantinos Spargias | Transcatheter prosthetic heart valve and delivery system |
EP3028668A1 (en) * | 2014-12-05 | 2016-06-08 | Nvt Ag | Prosthetic heart valve system and delivery system therefor |
CN110141399B (en) | 2015-02-05 | 2021-07-27 | 卡迪尔维尔福股份有限公司 | Prosthetic valve with axially sliding frame |
US9974651B2 (en) | 2015-02-05 | 2018-05-22 | Mitral Tech Ltd. | Prosthetic valve with axially-sliding frames |
US20160256269A1 (en) | 2015-03-05 | 2016-09-08 | Mitralign, Inc. | Devices for treating paravalvular leakage and methods use thereof |
BR112017019934B1 (en) | 2015-03-19 | 2023-01-17 | Caisson Interventional, LLC | PROSTHETIC MITRAL VALVE SYSTEM AND ANCHOR ASSEMBLY OF A PROSTHETIC MITRAL VALVE SYSTEM |
US9962260B2 (en) | 2015-03-24 | 2018-05-08 | St. Jude Medical, Cardiology Division, Inc. | Prosthetic mitral valve |
US10441416B2 (en) | 2015-04-21 | 2019-10-15 | Edwards Lifesciences Corporation | Percutaneous mitral valve replacement device |
CR20170480A (en) | 2015-04-30 | 2018-02-21 | Valtech Cardio Ltd | Annuloplasty technologies |
US10376363B2 (en) | 2015-04-30 | 2019-08-13 | Edwards Lifesciences Cardiaq Llc | Replacement mitral valve, delivery system for replacement mitral valve and methods of use |
CA2990872C (en) | 2015-06-22 | 2022-03-22 | Edwards Lifescience Cardiaq Llc | Actively controllable heart valve implant and methods of controlling same |
US10092400B2 (en) | 2015-06-23 | 2018-10-09 | Edwards Lifesciences Cardiaq Llc | Systems and methods for anchoring and sealing a prosthetic heart valve |
CR20170597A (en) | 2015-07-02 | 2018-04-20 | Edwards Lifesciences Corp | INTEGRATED HYBRID HEART VALVES |
CN107735051B (en) | 2015-07-02 | 2020-07-31 | 爱德华兹生命科学公司 | Hybrid heart valve adapted for post-implant expansion |
CN107920895B (en) | 2015-08-21 | 2020-06-26 | 托尔福公司 | Implantable heart valve devices, mitral valve repair devices, and associated systems and methods |
US10117744B2 (en) | 2015-08-26 | 2018-11-06 | Edwards Lifesciences Cardiaq Llc | Replacement heart valves and methods of delivery |
US10575951B2 (en) | 2015-08-26 | 2020-03-03 | Edwards Lifesciences Cardiaq Llc | Delivery device and methods of use for transapical delivery of replacement mitral valve |
US10350066B2 (en) | 2015-08-28 | 2019-07-16 | Edwards Lifesciences Cardiaq Llc | Steerable delivery system for replacement mitral valve and methods of use |
CN108135592B (en) | 2015-09-02 | 2021-05-14 | 爱德华兹生命科学公司 | Spacer for securing a transcatheter valve to a bioprosthetic cardiac structure |
US10080653B2 (en) | 2015-09-10 | 2018-09-25 | Edwards Lifesciences Corporation | Limited expansion heart valve |
US10426482B2 (en) | 2015-09-15 | 2019-10-01 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Devices and methods for effectuating percutaneous Glenn and Fontan procedures |
US9592121B1 (en) | 2015-11-06 | 2017-03-14 | Middle Peak Medical, Inc. | Device, system, and method for transcatheter treatment of valvular regurgitation |
US10751182B2 (en) | 2015-12-30 | 2020-08-25 | Edwards Lifesciences Corporation | System and method for reshaping right heart |
WO2017117370A2 (en) | 2015-12-30 | 2017-07-06 | Mitralign, Inc. | System and method for reducing tricuspid regurgitation |
WO2017117388A1 (en) | 2015-12-30 | 2017-07-06 | Caisson Interventional, LLC | Systems and methods for heart valve therapy |
US11833034B2 (en) | 2016-01-13 | 2023-12-05 | Shifamed Holdings, Llc | Prosthetic cardiac valve devices, systems, and methods |
CN108882981B (en) | 2016-01-29 | 2021-08-10 | 内奥瓦斯克迪亚拉公司 | Prosthetic valve for preventing outflow obstruction |
US10531866B2 (en) | 2016-02-16 | 2020-01-14 | Cardiovalve Ltd. | Techniques for providing a replacement valve and transseptal communication |
US10667904B2 (en) | 2016-03-08 | 2020-06-02 | Edwards Lifesciences Corporation | Valve implant with integrated sensor and transmitter |
US10973527B2 (en) * | 2016-03-11 | 2021-04-13 | Hemant Deshmukh | Low profile, self-expanding, blood flow resisting device |
USD815744S1 (en) | 2016-04-28 | 2018-04-17 | Edwards Lifesciences Cardiaq Llc | Valve frame for a delivery system |
CN109069272A (en) | 2016-04-29 | 2018-12-21 | 美敦力瓦斯科尔勒公司 | Prosthetic heart valve equipment and associated system and method with the anchor log with tether |
US10456245B2 (en) | 2016-05-16 | 2019-10-29 | Edwards Lifesciences Corporation | System and method for applying material to a stent |
US10702274B2 (en) | 2016-05-26 | 2020-07-07 | Edwards Lifesciences Corporation | Method and system for closing left atrial appendage |
GB201611910D0 (en) | 2016-07-08 | 2016-08-24 | Valtech Cardio Ltd | Adjustable annuloplasty device with alternating peaks and troughs |
US10828150B2 (en) * | 2016-07-08 | 2020-11-10 | Edwards Lifesciences Corporation | Docking station for heart valve prosthesis |
US10350062B2 (en) | 2016-07-21 | 2019-07-16 | Edwards Lifesciences Corporation | Replacement heart valve prosthesis |
USD800908S1 (en) | 2016-08-10 | 2017-10-24 | Mitraltech Ltd. | Prosthetic valve element |
EP3496664B1 (en) | 2016-08-10 | 2021-09-29 | Cardiovalve Ltd | Prosthetic valve with concentric frames |
CA3033666A1 (en) | 2016-08-19 | 2018-02-22 | Edwards Lifesciences Corporation | Steerable delivery system for replacement mitral valve and methods of use |
ES2902516T3 (en) | 2016-08-26 | 2022-03-28 | St Jude Medical Cardiology Div Inc | Prosthetic heart valve with paravalvular leak mitigation features |
EP3964173B1 (en) | 2016-08-26 | 2024-04-10 | Edwards Lifesciences Corporation | Multi-portion replacement heart valve prosthesis |
EP3512466B1 (en) | 2016-09-15 | 2020-07-29 | St. Jude Medical, Cardiology Division, Inc. | Prosthetic heart valve with paravalvular leak mitigation features |
US11241307B2 (en) | 2016-10-13 | 2022-02-08 | Boston Scientific Scimed, Inc. | Replacement heart valve with diaphragm |
EP3531977A1 (en) | 2016-10-28 | 2019-09-04 | St. Jude Medical, Cardiology Division, Inc. | Prosthetic mitral valve |
US10758348B2 (en) | 2016-11-02 | 2020-09-01 | Edwards Lifesciences Corporation | Supra and sub-annular mitral valve delivery system |
EP3541462A4 (en) | 2016-11-21 | 2020-06-17 | Neovasc Tiara Inc. | Methods and systems for rapid retraction of a transcatheter heart valve delivery system |
USD846122S1 (en) | 2016-12-16 | 2019-04-16 | Edwards Lifesciences Corporation | Heart valve sizer |
US10478303B2 (en) | 2017-03-13 | 2019-11-19 | Polares Medical Inc. | Device, system, and method for transcatheter treatment of valvular regurgitation |
EP3595587A4 (en) | 2017-03-13 | 2020-11-11 | Polares Medical Inc. | Device, system, and method for transcatheter treatment of valvular regurgitation |
US10653524B2 (en) | 2017-03-13 | 2020-05-19 | Polares Medical Inc. | Device, system, and method for transcatheter treatment of valvular regurgitation |
US10463485B2 (en) | 2017-04-06 | 2019-11-05 | Edwards Lifesciences Corporation | Prosthetic valve holders with automatic deploying mechanisms |
US10575950B2 (en) | 2017-04-18 | 2020-03-03 | Twelve, Inc. | Hydraulic systems for delivering prosthetic heart valve devices and associated methods |
US10433961B2 (en) | 2017-04-18 | 2019-10-08 | Twelve, Inc. | Delivery systems with tethers for prosthetic heart valve devices and associated methods |
US10702378B2 (en) | 2017-04-18 | 2020-07-07 | Twelve, Inc. | Prosthetic heart valve device and associated systems and methods |
US11045627B2 (en) | 2017-04-18 | 2021-06-29 | Edwards Lifesciences Corporation | Catheter system with linear actuation control mechanism |
EP3614969B1 (en) | 2017-04-28 | 2023-05-03 | Edwards Lifesciences Corporation | Prosthetic heart valve with collapsible holder |
US10888646B2 (en) | 2017-04-28 | 2021-01-12 | Nuheart As | Ventricular assist device and method |
US10537670B2 (en) | 2017-04-28 | 2020-01-21 | Nuheart As | Ventricular assist device and method |
US10792151B2 (en) | 2017-05-11 | 2020-10-06 | Twelve, Inc. | Delivery systems for delivering prosthetic heart valve devices and associated methods |
USD875935S1 (en) | 2017-05-15 | 2020-02-18 | St. Jude Medical, Cardiology Division, Inc. | Stent having tapered struts |
USD875250S1 (en) | 2017-05-15 | 2020-02-11 | St. Jude Medical, Cardiology Division, Inc. | Stent having tapered aortic struts |
USD889653S1 (en) | 2017-05-15 | 2020-07-07 | St. Jude Medical, Cardiology Division, Inc. | Stent having tapered struts |
US10646338B2 (en) | 2017-06-02 | 2020-05-12 | Twelve, Inc. | Delivery systems with telescoping capsules for deploying prosthetic heart valve devices and associated methods |
US10709591B2 (en) | 2017-06-06 | 2020-07-14 | Twelve, Inc. | Crimping device and method for loading stents and prosthetic heart valves |
EP3641700A4 (en) | 2017-06-21 | 2020-08-05 | Edwards Lifesciences Corporation | Dual-wireform limited expansion heart valves |
AU2018291171B2 (en) | 2017-06-30 | 2023-11-30 | Edwards Lifesciences Corporation | Lock and release mechanisms for trans-catheter implantable devices |
SG11201912180QA (en) * | 2017-06-30 | 2020-01-30 | Edwards Lifesciences Corp | Docking stations transcatheter valves |
US10786352B2 (en) * | 2017-07-06 | 2020-09-29 | Twelve, Inc. | Prosthetic heart valve devices and associated systems and methods |
US10729541B2 (en) | 2017-07-06 | 2020-08-04 | Twelve, Inc. | Prosthetic heart valve devices and associated systems and methods |
ES2923913T3 (en) | 2017-07-06 | 2022-10-03 | Edwards Lifesciences Corp | Steerable rail supply system |
US10537426B2 (en) | 2017-08-03 | 2020-01-21 | Cardiovalve Ltd. | Prosthetic heart valve |
US10575948B2 (en) | 2017-08-03 | 2020-03-03 | Cardiovalve Ltd. | Prosthetic heart valve |
US11793633B2 (en) | 2017-08-03 | 2023-10-24 | Cardiovalve Ltd. | Prosthetic heart valve |
US10888421B2 (en) | 2017-09-19 | 2021-01-12 | Cardiovalve Ltd. | Prosthetic heart valve with pouch |
US11246704B2 (en) | 2017-08-03 | 2022-02-15 | Cardiovalve Ltd. | Prosthetic heart valve |
EP3672530A4 (en) | 2017-08-25 | 2021-04-14 | Neovasc Tiara Inc. | Sequentially deployed transcatheter mitral valve prosthesis |
US11382751B2 (en) | 2017-10-24 | 2022-07-12 | St. Jude Medical, Cardiology Division, Inc. | Self-expandable filler for mitigating paravalvular leak |
US10835221B2 (en) | 2017-11-02 | 2020-11-17 | Valtech Cardio, Ltd. | Implant-cinching devices and systems |
US11135062B2 (en) | 2017-11-20 | 2021-10-05 | Valtech Cardio Ltd. | Cinching of dilated heart muscle |
GB201720803D0 (en) | 2017-12-13 | 2018-01-24 | Mitraltech Ltd | Prosthetic Valve and delivery tool therefor |
GB201800399D0 (en) | 2018-01-10 | 2018-02-21 | Mitraltech Ltd | Temperature-control during crimping of an implant |
US11337805B2 (en) | 2018-01-23 | 2022-05-24 | Edwards Lifesciences Corporation | Prosthetic valve holders, systems, and methods |
EP3743015A1 (en) | 2018-01-24 | 2020-12-02 | Valtech Cardio, Ltd. | Contraction of an annuloplasty structure |
CN117481869A (en) | 2018-01-25 | 2024-02-02 | 爱德华兹生命科学公司 | Delivery system for assisting in recapture and repositioning of replacement valves after deployment |
WO2019145941A1 (en) | 2018-01-26 | 2019-08-01 | Valtech Cardio, Ltd. | Techniques for facilitating heart valve tethering and chord replacement |
US11051934B2 (en) | 2018-02-28 | 2021-07-06 | Edwards Lifesciences Corporation | Prosthetic mitral valve with improved anchors and seal |
US11813413B2 (en) | 2018-03-27 | 2023-11-14 | St. Jude Medical, Cardiology Division, Inc. | Radiopaque outer cuff for transcatheter valve |
US10441449B1 (en) | 2018-05-30 | 2019-10-15 | Vesper Medical, Inc. | Rotary handle stent delivery system and method |
USD908874S1 (en) | 2018-07-11 | 2021-01-26 | Edwards Lifesciences Corporation | Collapsible heart valve sizer |
CR20210020A (en) | 2018-07-12 | 2021-07-21 | Valtech Cardio Ltd | Annuloplasty systems and locking tools therefor |
US10449073B1 (en) | 2018-09-18 | 2019-10-22 | Vesper Medical, Inc. | Rotary handle stent delivery system and method |
EP3852679A1 (en) | 2018-09-20 | 2021-07-28 | St. Jude Medical, Cardiology Division, Inc. | Attachment of leaflets to prosthetic heart valve |
JP2022504241A (en) | 2018-10-05 | 2022-01-13 | シファメド・ホールディングス・エルエルシー | Artificial heart valve device, system, and method |
CN112822991A (en) * | 2018-10-10 | 2021-05-18 | 得维医疗有限公司 | Implant for treating and/or replacing inflamed, thrombosed or degenerated heart valves |
US11364117B2 (en) | 2018-10-15 | 2022-06-21 | St. Jude Medical, Cardiology Division, Inc. | Braid connections for prosthetic heart valves |
JP7260930B2 (en) | 2018-11-08 | 2023-04-19 | ニオバスク ティアラ インコーポレイテッド | Ventricular deployment of a transcatheter mitral valve prosthesis |
WO2020123267A1 (en) | 2018-12-10 | 2020-06-18 | St. Jude Medical, Cardiology Division, Inc. | Prosthetic tricuspid valve replacement design |
EP3902503A1 (en) | 2018-12-26 | 2021-11-03 | St. Jude Medical, Cardiology Division, Inc. | Elevated outer cuff for reducing paravalvular leakage and increasing stent fatigue life |
US11723783B2 (en) | 2019-01-23 | 2023-08-15 | Neovasc Medical Ltd. | Covered flow modifying apparatus |
CN113573650A (en) | 2019-03-15 | 2021-10-29 | 后续医疗股份有限公司 | Wire device with flexible connection for treating vascular defects |
EP3908209A4 (en) | 2019-03-15 | 2022-10-19 | Sequent Medical, Inc. | Filamentary devices for treatment of vascular defects |
WO2020190639A1 (en) | 2019-03-15 | 2020-09-24 | Sequent Medical, Inc. | Filamentary devices for treatment of vascular defects |
EP3941391A4 (en) | 2019-03-19 | 2022-11-23 | Shifamed Holdings, LLC | Prosthetic cardiac valve devices, systems, and methods |
EP3946163A4 (en) | 2019-04-01 | 2022-12-21 | Neovasc Tiara Inc. | Controllably deployable prosthetic valve |
CN113924065A (en) | 2019-04-10 | 2022-01-11 | 内奥瓦斯克迪亚拉公司 | Prosthetic valve with natural blood flow |
EP3932336A4 (en) * | 2019-04-29 | 2022-11-23 | Mallow Medical (Shanghai) Co., Ltd. | Occluder with no externally protruding structure at either end |
EP3972673A4 (en) | 2019-05-20 | 2023-06-07 | Neovasc Tiara Inc. | Introducer with hemostasis mechanism |
WO2020257643A1 (en) * | 2019-06-20 | 2020-12-24 | Neovasc Tiara Inc. | Low profile prosthetic mitral valve |
KR20220122966A (en) | 2019-10-29 | 2022-09-05 | 에드워즈 라이프사이언시스 이노베이션 (이스라엘) 리미티드 | Annuloplasty and Tissue Anchor Techniques |
WO2021126778A1 (en) | 2019-12-16 | 2021-06-24 | Edwards Lifesciences Corporation | Valve holder assembly with suture looping protection |
US11219541B2 (en) | 2020-05-21 | 2022-01-11 | Vesper Medical, Inc. | Wheel lock for thumbwheel actuated device |
US11938022B2 (en) | 2020-06-26 | 2024-03-26 | Highlife Sas | Transcatheter valve prosthesis and method for implanting the same |
WO2022022574A1 (en) * | 2020-07-28 | 2022-02-03 | 北京迈迪顶峰医疗科技股份有限公司 | Prosthetic valve |
DE102020209823A1 (en) | 2020-08-04 | 2022-02-10 | EPflex Feinwerktechnik GmbH. | Tubular instrument with self-expanding wire structure |
US11197755B1 (en) * | 2020-10-28 | 2021-12-14 | Occam Labs LLC | Systems, devices and methods for folded unibody heart valve stents |
US11464634B2 (en) | 2020-12-16 | 2022-10-11 | Polares Medical Inc. | Device, system, and method for transcatheter treatment of valvular regurgitation with secondary anchors |
US11759321B2 (en) | 2021-06-25 | 2023-09-19 | Polares Medical Inc. | Device, system, and method for transcatheter treatment of valvular regurgitation |
CN117224278B (en) * | 2023-11-10 | 2024-02-27 | 广东脉搏医疗科技有限公司 | Lumen flow regulator and coronary sinus constriction device |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20040236411A1 (en) * | 2001-07-19 | 2004-11-25 | The Cleveland Clinic Foundation | Prosthetic cardiac valve and method for making same |
US20060167543A1 (en) * | 1999-12-31 | 2006-07-27 | Bailey Steven R | Endoluminal cardiac and venous valve prostheses and methods of manufacture and delivery thereof |
US20080071362A1 (en) * | 2006-09-19 | 2008-03-20 | Yosi Tuval | Valve prosthesis implantation techniques |
Family Cites Families (202)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3365190D1 (en) | 1982-01-20 | 1986-09-18 | Martin Morris Black | Artificial heart valves |
CA1303298C (en) | 1986-08-06 | 1992-06-16 | Alain Carpentier | Flexible cardiac valvular support prosthesis |
US5746775A (en) | 1988-04-01 | 1998-05-05 | The Board Of Regent6S Of The University Of Michigan | Method of making calcification-resistant bioprosthetic tissue |
US5094661A (en) | 1988-04-01 | 1992-03-10 | The University Of Michigan | Calcification-resistant materials and methods of making same through use of trivalent aluminum |
US5368608A (en) | 1988-04-01 | 1994-11-29 | University Of Michigan, The Board Of Regents | Calcification-resistant materials and methods of making same through use of multivalent cations |
DE69010890T2 (en) * | 1989-02-13 | 1995-03-16 | Baxter Int | PARTLY FLEXIBLE RING-SHAPED PROSTHESIS FOR IMPLANTING AROUND THE HEART-VALVE RING. |
US5002566A (en) * | 1989-02-17 | 1991-03-26 | Baxter International Inc. | Calcification mitigation of bioprosthetic implants |
CA2046592C (en) | 1989-02-17 | 2000-05-02 | Aws Nashef | Calcification mitigation of bioprosthetic implants |
US5352240A (en) | 1989-05-31 | 1994-10-04 | Promedica International, Inc. | Human heart valve replacement with porcine pulmonary valve |
AU626686B2 (en) | 1989-06-09 | 1992-08-06 | Medtronic, Inc. | Dynamic fixation of porcine aortic valves |
US5035706A (en) * | 1989-10-17 | 1991-07-30 | Cook Incorporated | Percutaneous stent and method for retrieval thereof |
US5411552A (en) * | 1990-05-18 | 1995-05-02 | Andersen; Henning R. | Valve prothesis for implantation in the body and a catheter for implanting such valve prothesis |
DK124690D0 (en) | 1990-05-18 | 1990-05-18 | Henning Rud Andersen | FAT PROTECTION FOR IMPLEMENTATION IN THE BODY FOR REPLACEMENT OF NATURAL FLEET AND CATS FOR USE IN IMPLEMENTING A SUCH FAT PROTECTION |
US5197979A (en) | 1990-09-07 | 1993-03-30 | Baxter International Inc. | Stentless heart valve and holder |
IT1245750B (en) | 1991-05-24 | 1994-10-14 | Sorin Biomedica Emodialisi S R | CARDIAC VALVE PROSTHESIS, PARTICULARLY FOR REPLACING THE AORTIC VALVE |
US5456713A (en) | 1991-10-25 | 1995-10-10 | Cook Incorporated | Expandable transluminal graft prosthesis for repairs of aneurysm and method for implanting |
AU669338B2 (en) * | 1991-10-25 | 1996-06-06 | Cook Incorporated | Expandable transluminal graft prosthesis for repair of aneurysm and method for implanting |
US5332402A (en) | 1992-05-12 | 1994-07-26 | Teitelbaum George P | Percutaneously-inserted cardiac valve |
EP0657147B1 (en) | 1993-11-04 | 1999-08-04 | C.R. Bard, Inc. | Non-migrating vascular prosthesis |
US5509930A (en) * | 1993-12-17 | 1996-04-23 | Autogenics | Stentless heart valve |
KR100365573B1 (en) * | 1994-03-14 | 2004-08-25 | 크라이어라이프, 인크. | Transplantation tissue and its manufacturing method |
US5595571A (en) * | 1994-04-18 | 1997-01-21 | Hancock Jaffe Laboratories | Biological material pre-fixation treatment |
US5683451A (en) | 1994-06-08 | 1997-11-04 | Cardiovascular Concepts, Inc. | Apparatus and methods for deployment release of intraluminal prostheses |
US5824041A (en) | 1994-06-08 | 1998-10-20 | Medtronic, Inc. | Apparatus and methods for placement and repositioning of intraluminal prostheses |
KR0131046B1 (en) | 1994-07-13 | 1998-04-14 | 김은영 | Calcification-resistant tissue heart valve |
NZ292690A (en) | 1994-09-01 | 1998-06-26 | Upjohn Co | Parenteral formulations comprising a lazaroid steroid, buffer, cosolvent and water |
US5549666A (en) | 1994-09-02 | 1996-08-27 | Baxter International Inc. | Natural tissue valve prostheses having variably complaint leaflets |
US5674298A (en) | 1994-10-21 | 1997-10-07 | The Board Of Regents Of The University Of Michigan | Calcification-resistant bioprosthetic tissue and methods of making same |
US5824080A (en) | 1995-09-28 | 1998-10-20 | The General Hospital Corporation | Photochemistry for the preparation of biologic grafts--allografts and xenografts |
BE1009746A3 (en) * | 1995-11-07 | 1997-07-01 | Dereume Jean Pierre Georges Em | Capture device introduced in a cavity of a human or animal body. |
DE19546692C2 (en) | 1995-12-14 | 2002-11-07 | Hans-Reiner Figulla | Self-expanding heart valve prosthesis for implantation in the human body via a catheter system |
DE69722388T2 (en) * | 1996-03-04 | 2004-04-22 | Edwards Lifesciences Corp., Irvine | NON-POLYMER EPOXY COMPOUNDS FOR CROSSLINKING BIOLOGICAL TISSUE AND BIOPROTHESES MADE THEREOF |
DE69738786D1 (en) | 1996-05-08 | 2008-07-31 | Sorin Biomedica Cardio Srl | A stent for angioplasty |
US8728143B2 (en) | 1996-06-06 | 2014-05-20 | Biosensors International Group, Ltd. | Endoprosthesis deployment system for treating vascular bifurcations |
US7238197B2 (en) * | 2000-05-30 | 2007-07-03 | Devax, Inc. | Endoprosthesis deployment system for treating vascular bifurcations |
JPH09327511A (en) | 1996-06-12 | 1997-12-22 | A S A Sangyo Kk | Method for recovering and regenerating peritoneal dialysis liquid and treating device and ancillary appliance for this purpose |
EP0850607A1 (en) | 1996-12-31 | 1998-07-01 | Cordis Corporation | Valve prosthesis for implantation in body channels |
US5841382A (en) | 1997-03-19 | 1998-11-24 | Lucent Technologies Inc. | Fast testing of D/A converters |
US5928281A (en) | 1997-03-27 | 1999-07-27 | Baxter International Inc. | Tissue heart valves |
WO1998046165A1 (en) * | 1997-04-11 | 1998-10-22 | Cryolife, Inc. | Tissue decellularization |
IL121316A (en) | 1997-07-15 | 2001-07-24 | Litana Ltd | Implantable medical device of shape memory alloy |
EP1281357A3 (en) | 1997-09-26 | 2003-07-09 | Duke University | Perfusion-occlusion catheter and methods |
US6120534A (en) * | 1997-10-29 | 2000-09-19 | Ruiz; Carlos E. | Endoluminal prosthesis having adjustable constriction |
IT1296619B1 (en) | 1997-12-10 | 1999-07-14 | Sorin Biomedica Cardio Spa | PROCEDURE FOR THE TREATMENT OF OPEN STRUCTURE PROSTHESES AND RELATED DEVICES. |
US6001126A (en) | 1997-12-24 | 1999-12-14 | Baxter International Inc. | Stentless bioprosthetic heart valve with coronary protuberances and related methods for surgical repair of defective heart valves |
US6027530A (en) | 1997-12-24 | 2000-02-22 | Baxter International Inc. | System, apparatus and method for chemical fixation of stentless cardiac valvular bioprostheses |
US7722671B1 (en) | 1998-01-27 | 2010-05-25 | St. Jude Medical, Inc. | Medical devices with associated growth factors |
US6093530A (en) | 1998-02-06 | 2000-07-25 | Sulzer Carbomedics Inc. | Non-calcific biomaterial by glutaraldehyde followed by oxidative fixation |
US5935163A (en) | 1998-03-31 | 1999-08-10 | Shelhigh, Inc. | Natural tissue heart valve prosthesis |
JP4399585B2 (en) | 1998-06-02 | 2010-01-20 | クック インコーポレイティド | Multi-sided medical device |
US7452371B2 (en) | 1999-06-02 | 2008-11-18 | Cook Incorporated | Implantable vascular device |
US5979949A (en) * | 1998-06-15 | 1999-11-09 | Kason Industries, Inc. | Sliding door latch with lock-out protection |
US6117169A (en) | 1998-06-24 | 2000-09-12 | Sulzer Carbomedics Inc. | Living hinge attachment of leaflet to a valve body |
JP2002518131A (en) | 1998-06-24 | 2002-06-25 | サルザー カーボメディクス インコーポレイテッド | A heart valve leaflet coupling structure that changes to affect the location and magnitude of the maximum load pressure on the leaflet |
US6254636B1 (en) | 1998-06-26 | 2001-07-03 | St. Jude Medical, Inc. | Single suture biological tissue aortic stentless valve |
US6254564B1 (en) * | 1998-09-10 | 2001-07-03 | Percardia, Inc. | Left ventricular conduit with blood vessel graft |
JP4663120B2 (en) | 1998-09-30 | 2011-03-30 | メドトロニック,インコーポレイテッド | Methods for reducing mineralization of tissues used in transplantation |
US6214055B1 (en) * | 1998-10-30 | 2001-04-10 | Mures Cardiovascular Research, Inc. | Method and kit for rapid preparation of autologous tissue medical devices |
FR2785174A1 (en) | 1998-11-03 | 2000-05-05 | Jacques Seguin | BODY CONDUIT EXTENSIONER, ESPECIALLY VASCULAR |
DE19857887B4 (en) * | 1998-12-15 | 2005-05-04 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Anchoring support for a heart valve prosthesis |
FR2788217A1 (en) * | 1999-01-12 | 2000-07-13 | Brice Letac | PROSTHETIC VALVE IMPLANTABLE BY CATHETERISM, OR SURGICAL |
DE60037309T2 (en) * | 1999-01-26 | 2008-11-27 | Edwards Lifesciences Corp., Irvine | FLEXIBLE HEART FLAP |
US6558418B2 (en) * | 1999-01-26 | 2003-05-06 | Edwards Lifesciences Corporation | Flexible heart valve |
US6736845B2 (en) * | 1999-01-26 | 2004-05-18 | Edwards Lifesciences Corporation | Holder for flexible heart valve |
US6425916B1 (en) * | 1999-02-10 | 2002-07-30 | Michi E. Garrison | Methods and devices for implanting cardiac valves |
US6287338B1 (en) | 1999-03-10 | 2001-09-11 | Sulzer Carbomedics Inc. | Pre-stressing devices incorporating materials subject to stress softening |
US6177514B1 (en) * | 1999-04-09 | 2001-01-23 | Sulzer Carbomedics Inc. | Blocked functional reagants for cross-linking biological tissues |
US6283995B1 (en) | 1999-04-15 | 2001-09-04 | Sulzer Carbomedics Inc. | Heart valve leaflet with scalloped free margin |
US6231602B1 (en) * | 1999-04-16 | 2001-05-15 | Edwards Lifesciences Corporation | Aortic annuloplasty ring |
WO2000064371A1 (en) | 1999-04-27 | 2000-11-02 | The Children's Hospital Of Philadelphia | Stabilization of implantable bioprosthetic devices |
US6478819B2 (en) | 1999-05-27 | 2002-11-12 | Sulzer Carbomedics Inc. | Prosthetic heart valves with flexible post geometry |
US7628803B2 (en) * | 2001-02-05 | 2009-12-08 | Cook Incorporated | Implantable vascular device |
US6521179B1 (en) * | 1999-08-11 | 2003-02-18 | Biomedical Design, Inc. | Sterilization |
US6183481B1 (en) * | 1999-09-22 | 2001-02-06 | Endomed Inc. | Delivery system for self-expanding stents and grafts |
US20020123790A1 (en) | 1999-09-28 | 2002-09-05 | White Geoffrey Hamilton | Enhanced engagement member for anchoring prosthetic devices in body lumen |
US20070043435A1 (en) * | 1999-11-17 | 2007-02-22 | Jacques Seguin | Non-cylindrical prosthetic valve system for transluminal delivery |
FR2800984B1 (en) | 1999-11-17 | 2001-12-14 | Jacques Seguin | DEVICE FOR REPLACING A HEART VALVE PERCUTANEOUSLY |
US7018406B2 (en) | 1999-11-17 | 2006-03-28 | Corevalve Sa | Prosthetic valve for transluminal delivery |
US8579966B2 (en) | 1999-11-17 | 2013-11-12 | Medtronic Corevalve Llc | Prosthetic valve for transluminal delivery |
FR2815844B1 (en) | 2000-10-31 | 2003-01-17 | Jacques Seguin | TUBULAR SUPPORT FOR THE PERCUTANEOUS POSITIONING OF A REPLACEMENT HEART VALVE |
US20030097175A1 (en) | 1999-12-08 | 2003-05-22 | O'connor Bernard | Heart valve prosthesis and method of manufacture |
GB9928905D0 (en) | 1999-12-08 | 2000-02-02 | Aortech Europ Ltd | Prosthesis |
US6471723B1 (en) | 2000-01-10 | 2002-10-29 | St. Jude Medical, Inc. | Biocompatible prosthetic tissue |
CN1404376A (en) | 2000-01-27 | 2003-03-19 | 3F治疗有限公司 | Prosthetic heart valve |
US6872226B2 (en) * | 2001-01-29 | 2005-03-29 | 3F Therapeutics, Inc. | Method of cutting material for use in implantable medical device |
EP1900343B1 (en) | 2000-01-31 | 2015-10-21 | Cook Biotech Incorporated | Stent valves |
ES2286097T7 (en) * | 2000-01-31 | 2009-11-05 | Cook Biotech, Inc | ENDOPROTESIS VALVES. |
US6821297B2 (en) | 2000-02-02 | 2004-11-23 | Robert V. Snyders | Artificial heart valve, implantation instrument and method therefor |
US6540782B1 (en) * | 2000-02-02 | 2003-04-01 | Robert V. Snyders | Artificial heart valve |
KR100786028B1 (en) | 2000-02-03 | 2007-12-17 | 쿡 인코포레이티드 | Implantable vascular device |
US6391538B1 (en) | 2000-02-09 | 2002-05-21 | The Children's Hospital Of Philadelphia | Stabilization of implantable bioprosthetic tissue |
US6344044B1 (en) | 2000-02-11 | 2002-02-05 | Edwards Lifesciences Corp. | Apparatus and methods for delivery of intraluminal prosthesis |
DE10010073B4 (en) | 2000-02-28 | 2005-12-22 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Anchoring for implantable heart valve prostheses |
DE10010074B4 (en) | 2000-02-28 | 2005-04-14 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Device for fastening and anchoring heart valve prostheses |
DE20003874U1 (en) | 2000-02-28 | 2000-05-25 | Fraunhofer Ges Forschung | Device for fastening and anchoring heart valve prostheses |
US6454799B1 (en) | 2000-04-06 | 2002-09-24 | Edwards Lifesciences Corporation | Minimally-invasive heart valves and methods of use |
US20030139803A1 (en) | 2000-05-30 | 2003-07-24 | Jacques Sequin | Method of stenting a vessel with stent lumenal diameter increasing distally |
WO2002022054A1 (en) * | 2000-09-12 | 2002-03-21 | Gabbay S | Valvular prosthesis and method of using same |
US7510572B2 (en) * | 2000-09-12 | 2009-03-31 | Shlomo Gabbay | Implantation system for delivery of a heart valve prosthesis |
DE10060660A1 (en) | 2000-12-06 | 2002-06-20 | Frey Rainer | Preservation of biological prostheses comprises treating the prosthesis with a solution containing a mixture of epoxy compounds of different lengths and then with a solution containing an antithrombotic agent |
US20070027535A1 (en) * | 2005-07-28 | 2007-02-01 | Cook Incorporated | Implantable thromboresistant valve |
US8038708B2 (en) | 2001-02-05 | 2011-10-18 | Cook Medical Technologies Llc | Implantable device with remodelable material and covering material |
JP2004022614A (en) * | 2002-06-13 | 2004-01-22 | Alps Electric Co Ltd | Magnetic sensor element and method of manufacturing the same |
US7556646B2 (en) * | 2001-09-13 | 2009-07-07 | Edwards Lifesciences Corporation | Methods and apparatuses for deploying minimally-invasive heart valves |
US7374571B2 (en) * | 2001-03-23 | 2008-05-20 | Edwards Lifesciences Corporation | Rolled minimally-invasive heart valves and methods of manufacture |
US20020143387A1 (en) * | 2001-03-27 | 2002-10-03 | Soetikno Roy M. | Stent repositioning and removal |
US7078163B2 (en) | 2001-03-30 | 2006-07-18 | Medtronic, Inc. | Process for reducing mineralization of tissue used in transplantation |
DE10121210B4 (en) | 2001-04-30 | 2005-11-17 | Universitätsklinikum Freiburg | Anchoring element for the intraluminal anchoring of a heart valve replacement and method for its production |
CA2449970A1 (en) | 2001-06-14 | 2002-12-27 | Cemvac System Ab | Method and device for preparation of bone cement |
FR2826863B1 (en) | 2001-07-04 | 2003-09-26 | Jacques Seguin | ASSEMBLY FOR PLACING A PROSTHETIC VALVE IN A BODY CONDUIT |
US20030027332A1 (en) * | 2001-07-16 | 2003-02-06 | Edwards Lifesciences Corporation | Tissue engineered heart valve |
WO2003009785A1 (en) | 2001-07-26 | 2003-02-06 | 3F Therapeutics, Inc. | Method of cutting material for use in implantable medical device |
FR2828091B1 (en) | 2001-07-31 | 2003-11-21 | Seguin Jacques | ASSEMBLY ALLOWING THE PLACEMENT OF A PROTHETIC VALVE IN A BODY DUCT |
FR2828263B1 (en) | 2001-08-03 | 2007-05-11 | Philipp Bonhoeffer | DEVICE FOR IMPLANTATION OF AN IMPLANT AND METHOD FOR IMPLANTATION OF THE DEVICE |
DE10138564B4 (en) | 2001-08-06 | 2007-07-12 | Lamm, Peter Wilhelm, Dr. | Method of devitalizing natural organs and / or providing extracellular matrices for tissue engineering |
US6821211B2 (en) | 2001-09-14 | 2004-11-23 | Golftech | Sport swing analysis system |
US20030065386A1 (en) | 2001-09-28 | 2003-04-03 | Weadock Kevin Shaun | Radially expandable endoprosthesis device with two-stage deployment |
US6893460B2 (en) | 2001-10-11 | 2005-05-17 | Percutaneous Valve Technologies Inc. | Implantable prosthetic valve |
US20030074055A1 (en) | 2001-10-17 | 2003-04-17 | Haverkost Patrick A. | Method and system for fixation of endoluminal devices |
US8308797B2 (en) * | 2002-01-04 | 2012-11-13 | Colibri Heart Valve, LLC | Percutaneously implantable replacement heart valve device and method of making same |
US7163556B2 (en) * | 2002-03-21 | 2007-01-16 | Providence Health System - Oregon | Bioprosthesis and method for suturelessly making same |
US7141064B2 (en) | 2002-05-08 | 2006-11-28 | Edwards Lifesciences Corporation | Compressed tissue for heart valve leaflets |
US7828839B2 (en) * | 2002-05-16 | 2010-11-09 | Cook Incorporated | Flexible barb for anchoring a prosthesis |
DE60334791D1 (en) | 2002-05-16 | 2010-12-16 | Cook Inc | FLEXIBLE RESISTANCE TO ANCHOR A PROSTHESIS |
US20040117004A1 (en) | 2002-05-16 | 2004-06-17 | Osborne Thomas A. | Stent and method of forming a stent with integral barbs |
US20040006380A1 (en) | 2002-07-05 | 2004-01-08 | Buck Jerrick C. | Stent delivery system |
DE10235237A1 (en) | 2002-08-01 | 2004-02-12 | Symetis Ag | In vitro preparation of homologous heart valves, useful for replacement of diseased valves, by inoculating biodegradable carrier with fibroblasts and attachment to a non-degradable stent |
DE10362367B3 (en) | 2002-08-13 | 2022-02-24 | Jenavalve Technology Inc. | Device for anchoring and aligning prosthetic heart valves |
DE10301026B4 (en) * | 2002-08-13 | 2014-10-30 | Jenavalve Technology Inc. | Device for anchoring and aligning heart valve prostheses |
CA2494970C (en) | 2002-08-15 | 2009-12-29 | Cook Incorporated | Stent and method of forming a stent with integral barbs |
EP2517674B1 (en) | 2002-08-15 | 2016-03-16 | Cook Medical Technologies LLC | Implantable vascular device |
WO2004017868A1 (en) * | 2002-08-23 | 2004-03-04 | William A. Cook Australia Pty. Ltd. | Asymmetric stent graft attachment |
US7137184B2 (en) | 2002-09-20 | 2006-11-21 | Edwards Lifesciences Corporation | Continuous heart valve support frame and method of manufacture |
CO5500017A1 (en) | 2002-09-23 | 2005-03-31 | 3F Therapeutics Inc | MITRAL PROTESTIC VALVE |
US20040153145A1 (en) | 2002-11-26 | 2004-08-05 | Clemson University | Fixation method for bioprostheses |
US7189259B2 (en) * | 2002-11-26 | 2007-03-13 | Clemson University | Tissue material and process for bioprosthesis |
KR20040046829A (en) | 2002-11-28 | 2004-06-05 | 현대자동차주식회사 | Shift control method and apparatus of an automatic transmission |
AU2003293267B2 (en) | 2002-12-04 | 2008-02-28 | Cook Incorporated | Device and method for treating thoracid aorta |
DE10362223B4 (en) | 2003-01-21 | 2010-02-04 | pfm Produkte für die Medizin AG | Basic coil shape |
US7399315B2 (en) | 2003-03-18 | 2008-07-15 | Edwards Lifescience Corporation | Minimally-invasive heart valve with cusp positioners |
US7625399B2 (en) | 2003-04-24 | 2009-12-01 | Cook Incorporated | Intralumenally-implantable frames |
US7717952B2 (en) * | 2003-04-24 | 2010-05-18 | Cook Incorporated | Artificial prostheses with preferred geometries |
US8221492B2 (en) | 2003-04-24 | 2012-07-17 | Cook Medical Technologies | Artificial valve prosthesis with improved flow dynamics |
US7658759B2 (en) * | 2003-04-24 | 2010-02-09 | Cook Incorporated | Intralumenally implantable frames |
US7201772B2 (en) | 2003-07-08 | 2007-04-10 | Ventor Technologies, Ltd. | Fluid flow prosthetic device |
AU2004253375B2 (en) | 2003-07-08 | 2011-07-14 | Ventor Technologies Ltd. | Implantable prosthetic devices particularly for transarterial delivery in the treatment of aortic stenosis, and methods of implanting such devices |
DE10335948B3 (en) * | 2003-08-04 | 2005-02-03 | Qualimed Innovative Medizinprodukte Gmbh | Stent for medical applications comprises a tubular support structure made from joined ring segments and twisted by a thread with ends guided into the support structure via a deviating unit and coupled by a connector |
US20050049692A1 (en) * | 2003-09-02 | 2005-03-03 | Numamoto Michael J. | Medical device for reduction of pressure effects of cardiac tricuspid valve regurgitation |
CZ300625B6 (en) * | 2003-09-25 | 2009-07-01 | Dr. Karel Volenec-Ella-Cs | Stent designed to stop esophageal variceal bleeding |
US20050075725A1 (en) * | 2003-10-02 | 2005-04-07 | Rowe Stanton J. | Implantable prosthetic valve with non-laminar flow |
US7955788B2 (en) | 2003-10-30 | 2011-06-07 | Medtronic, Inc. | Bioprosthetic tissue preparation with synthetic hydrogels |
US9078780B2 (en) * | 2003-11-08 | 2015-07-14 | Cook Medical Technologies Llc | Balloon flareable branch vessel prosthesis and method |
US7476256B2 (en) * | 2003-12-09 | 2009-01-13 | Gi Dynamics, Inc. | Intestinal sleeve |
US7445631B2 (en) | 2003-12-23 | 2008-11-04 | Sadra Medical, Inc. | Methods and apparatus for endovascularly replacing a patient's heart valve |
US20050137687A1 (en) | 2003-12-23 | 2005-06-23 | Sadra Medical | Heart valve anchor and method |
US8840663B2 (en) * | 2003-12-23 | 2014-09-23 | Sadra Medical, Inc. | Repositionable heart valve method |
WO2005070343A1 (en) * | 2003-12-23 | 2005-08-04 | Laboratoires Perouse | Kit which is intended to be implanted in a conduit |
US8343213B2 (en) | 2003-12-23 | 2013-01-01 | Sadra Medical, Inc. | Leaflet engagement elements and methods for use thereof |
US7748389B2 (en) | 2003-12-23 | 2010-07-06 | Sadra Medical, Inc. | Leaflet engagement elements and methods for use thereof |
EP2526895B1 (en) | 2003-12-23 | 2014-01-29 | Sadra Medical, Inc. | Repositionable heart valve |
US7381219B2 (en) | 2003-12-23 | 2008-06-03 | Sadra Medical, Inc. | Low profile heart valve and delivery system |
JP4747245B2 (en) | 2003-12-31 | 2011-08-17 | 謙造 廣瀬 | Enzymatic construction method of RNAi library |
US7871435B2 (en) | 2004-01-23 | 2011-01-18 | Edwards Lifesciences Corporation | Anatomically approximate prosthetic mitral heart valve |
US7470285B2 (en) | 2004-02-05 | 2008-12-30 | Children's Medical Center Corp. | Transcatheter delivery of a replacement heart valve |
ITTO20040135A1 (en) | 2004-03-03 | 2004-06-03 | Sorin Biomedica Cardio Spa | CARDIAC VALVE PROSTHESIS |
JP5290573B2 (en) | 2004-04-23 | 2013-09-18 | メドトロニック スリーエフ セラピューティクス,インコーポレイティド | Implantable prosthetic valve |
WO2005118019A1 (en) | 2004-05-28 | 2005-12-15 | Cook Incorporated | Implantable bioabsorbable valve support frame |
US20050266390A1 (en) | 2004-06-01 | 2005-12-01 | Yuichiro Ueda | Processes for removing cells and cell debris from tissue and tissue constructs used in transplantation and tissue reconstruction |
US7422607B2 (en) * | 2004-08-24 | 2008-09-09 | Oviatt Henry W | Anti-calcification treatments for heart valves and vascular grafts |
WO2006052322A2 (en) * | 2004-09-22 | 2006-05-18 | Guterman Lee R | Cranial aneurysm treatment arrangement |
WO2006066327A1 (en) | 2004-12-24 | 2006-06-29 | Celxcel Pty Ltd | An implantable biomaterial and a method of producing same |
DE102005003632A1 (en) | 2005-01-20 | 2006-08-17 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Catheter for the transvascular implantation of heart valve prostheses |
US8445278B2 (en) * | 2005-03-01 | 2013-05-21 | Medtronic, Inc. | Process for producing decellularized biological tissues |
WO2006102063A2 (en) | 2005-03-19 | 2006-09-28 | Cook Biotech Incorporated | Prosthetic implants including ecm composite material |
US8062359B2 (en) | 2005-04-06 | 2011-11-22 | Edwards Lifesciences Corporation | Highly flexible heart valve connecting band |
US7914569B2 (en) | 2005-05-13 | 2011-03-29 | Medtronics Corevalve Llc | Heart valve prosthesis and methods of manufacture and use |
EP1883375B1 (en) | 2005-05-24 | 2016-12-07 | Edwards Lifesciences Corporation | Rapid deployment prosthetic heart valve |
US7238200B2 (en) | 2005-06-03 | 2007-07-03 | Arbor Surgical Technologies, Inc. | Apparatus and methods for making leaflets and valve prostheses including such leaflets |
US7780723B2 (en) * | 2005-06-13 | 2010-08-24 | Edwards Lifesciences Corporation | Heart valve delivery system |
US8685083B2 (en) | 2005-06-27 | 2014-04-01 | Edwards Lifesciences Corporation | Apparatus, system, and method for treatment of posterior leaflet prolapse |
US20070028291A1 (en) * | 2005-07-29 | 2007-02-01 | Bit 9, Inc. | Parametric content control in a network security system |
US20070038295A1 (en) * | 2005-08-12 | 2007-02-15 | Cook Incorporated | Artificial valve prosthesis having a ring frame |
US8470022B2 (en) * | 2005-08-31 | 2013-06-25 | Cook Biotech Incorporated | Implantable valve |
US8167932B2 (en) * | 2005-10-18 | 2012-05-01 | Edwards Lifesciences Corporation | Heart valve delivery system with valve catheter |
US7503928B2 (en) * | 2005-10-21 | 2009-03-17 | Cook Biotech Incorporated | Artificial valve with center leaflet attachment |
DE102005051849B4 (en) | 2005-10-28 | 2010-01-21 | JenaValve Technology Inc., Wilmington | Device for implantation and attachment of heart valve prostheses |
DE102005052628B4 (en) | 2005-11-04 | 2014-06-05 | Jenavalve Technology Inc. | Self-expanding, flexible wire mesh with integrated valvular prosthesis for the transvascular heart valve replacement and a system with such a device and a delivery catheter |
US8764820B2 (en) | 2005-11-16 | 2014-07-01 | Edwards Lifesciences Corporation | Transapical heart valve delivery system and method |
KR20080103510A (en) | 2005-12-22 | 2008-11-27 | 시메티스 에스에이 | Stent-valves for valve replacement and associated methods and systems for surgery |
US20070213813A1 (en) | 2005-12-22 | 2007-09-13 | Symetis Sa | Stent-valves for valve replacement and associated methods and systems for surgery |
US20070239271A1 (en) | 2006-04-10 | 2007-10-11 | Than Nguyen | Systems and methods for loading a prosthesis onto a minimally invasive delivery system |
US7806926B2 (en) | 2006-04-14 | 2010-10-05 | Edwards Lifesciences Corporation | Holders for prosthetic aortic heart valves |
EP3400908B1 (en) | 2006-05-30 | 2020-06-17 | Cook Medical Technologies LLC | Artificial valve prosthesis |
GR1005718B (en) | 2006-07-12 | 2007-11-07 | Ευσταθιος-Ανδρεας Αγαθος | Human cardiac valve replacement with seal aortic or pulmonary valve |
US20080021546A1 (en) * | 2006-07-18 | 2008-01-24 | Tim Patz | System for deploying balloon-expandable heart valves |
GB2440809B (en) | 2006-07-28 | 2011-08-10 | Geoffrey Douglas Tansley | Improved heart valve prosthesis |
ATE556673T1 (en) * | 2006-09-08 | 2012-05-15 | Edwards Lifesciences Corp | INTEGRATED HEART VALVE DELIVERY SYSTEM |
JP2010505597A (en) | 2006-10-10 | 2010-02-25 | セロノバ バイオサイエンシーズ, インコーポレイテッド | Bioprosthetic heart valve using polyphosphazene |
EP2077718B2 (en) | 2006-10-27 | 2022-03-09 | Edwards Lifesciences Corporation | Biological tissue for surgical implantation |
WO2008070797A2 (en) | 2006-12-06 | 2008-06-12 | Medtronic Corevalve, Inc. | System and method for transapical delivery of an annulus anchored self-expanding valve |
US8236045B2 (en) | 2006-12-22 | 2012-08-07 | Edwards Lifesciences Corporation | Implantable prosthetic valve assembly and method of making the same |
ATE515244T1 (en) | 2007-02-15 | 2011-07-15 | Cook Inc | ARTIFICIAL VALVE PROSTHESIS WITH FREE LEAF SECTION |
-
2005
- 2005-11-04 DE DE102005052628.4A patent/DE102005052628B4/en active Active
-
2006
- 2006-11-02 AU AU2006310681A patent/AU2006310681B2/en not_active Ceased
- 2006-11-02 JP JP2008539305A patent/JP4904362B2/en active Active
- 2006-11-02 EP EP06806665A patent/EP1942834B1/en active Active
- 2006-11-02 PT PT68066653T patent/PT1942834E/en unknown
- 2006-11-02 ES ES06806665T patent/ES2401451T3/en active Active
- 2006-11-02 DK DK06806665.3T patent/DK1942834T3/en active
- 2006-11-02 CA CA2627555A patent/CA2627555C/en not_active Expired - Fee Related
- 2006-11-02 SI SI200631543T patent/SI1942834T1/en unknown
- 2006-11-02 WO PCT/EP2006/010519 patent/WO2007051620A1/en active Application Filing
- 2006-11-02 PL PL06806665T patent/PL1942834T3/en unknown
- 2006-11-02 US US12/084,421 patent/US20090222076A1/en not_active Abandoned
- 2006-11-03 US US11/592,369 patent/US8062355B2/en active Active
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20060167543A1 (en) * | 1999-12-31 | 2006-07-27 | Bailey Steven R | Endoluminal cardiac and venous valve prostheses and methods of manufacture and delivery thereof |
US20040236411A1 (en) * | 2001-07-19 | 2004-11-25 | The Cleveland Clinic Foundation | Prosthetic cardiac valve and method for making same |
US20080071362A1 (en) * | 2006-09-19 | 2008-03-20 | Yosi Tuval | Valve prosthesis implantation techniques |
Cited By (417)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US10278805B2 (en) | 2000-08-18 | 2019-05-07 | Atritech, Inc. | Expandable implant devices for filtering blood flow from atrial appendages |
US8163008B2 (en) | 2002-08-28 | 2012-04-24 | Heart Leaflet Technologies, Inc. | Leaflet valve |
US11285002B2 (en) | 2003-12-23 | 2022-03-29 | Boston Scientific Scimed, Inc. | Methods and apparatus for endovascularly replacing a heart valve |
US11696825B2 (en) | 2003-12-23 | 2023-07-11 | Boston Scientific Scimed, Inc. | Replacement valve and anchor |
US10258465B2 (en) | 2003-12-23 | 2019-04-16 | Boston Scientific Scimed Inc. | Methods and apparatus for endovascular heart valve replacement comprising tissue grasping elements |
US10314695B2 (en) | 2003-12-23 | 2019-06-11 | Boston Scientific Scimed Inc. | Methods and apparatus for endovascular heart valve replacement comprising tissue grasping elements |
US7988724B2 (en) | 2003-12-23 | 2011-08-02 | Sadra Medical, Inc. | Systems and methods for delivering a medical implant |
US10335273B2 (en) | 2003-12-23 | 2019-07-02 | Boston Scientific Scimed Inc. | Leaflet engagement elements and methods for use thereof |
US8052749B2 (en) | 2003-12-23 | 2011-11-08 | Sadra Medical, Inc. | Methods and apparatus for endovascular heart valve replacement comprising tissue grasping elements |
US10357359B2 (en) | 2003-12-23 | 2019-07-23 | Boston Scientific Scimed Inc | Methods and apparatus for endovascularly replacing a patient's heart valve |
US10206774B2 (en) | 2003-12-23 | 2019-02-19 | Boston Scientific Scimed Inc. | Low profile heart valve and delivery system |
US10413412B2 (en) | 2003-12-23 | 2019-09-17 | Boston Scientific Scimed, Inc. | Methods and apparatus for endovascularly replacing a heart valve |
US8182528B2 (en) | 2003-12-23 | 2012-05-22 | Sadra Medical, Inc. | Locking heart valve anchor |
US8231670B2 (en) | 2003-12-23 | 2012-07-31 | Sadra Medical, Inc. | Repositionable heart valve and method |
US10413409B2 (en) | 2003-12-23 | 2019-09-17 | Boston Scientific Scimed, Inc. | Systems and methods for delivering a medical implant |
US9277991B2 (en) | 2003-12-23 | 2016-03-08 | Boston Scientific Scimed, Inc. | Low profile heart valve and delivery system |
US8252052B2 (en) | 2003-12-23 | 2012-08-28 | Sadra Medical, Inc. | Methods and apparatus for endovascularly replacing a patient's heart valve |
US10426608B2 (en) | 2003-12-23 | 2019-10-01 | Boston Scientific Scimed, Inc. | Repositionable heart valve |
US10478289B2 (en) | 2003-12-23 | 2019-11-19 | Boston Scientific Scimed, Inc. | Replacement valve and anchor |
US9308085B2 (en) | 2003-12-23 | 2016-04-12 | Boston Scientific Scimed, Inc. | Repositionable heart valve and method |
US9320599B2 (en) | 2003-12-23 | 2016-04-26 | Boston Scientific Scimed, Inc. | Methods and apparatus for endovascularly replacing a heart valve |
US8343213B2 (en) | 2003-12-23 | 2013-01-01 | Sadra Medical, Inc. | Leaflet engagement elements and methods for use thereof |
US9358110B2 (en) | 2003-12-23 | 2016-06-07 | Boston Scientific Scimed, Inc. | Medical devices and delivery systems for delivering medical devices |
US9358106B2 (en) | 2003-12-23 | 2016-06-07 | Boston Scientific Scimed Inc. | Methods and apparatus for performing valvuloplasty |
US9956075B2 (en) | 2003-12-23 | 2018-05-01 | Boston Scientific Scimed Inc. | Methods and apparatus for endovascularly replacing a heart valve |
US10716663B2 (en) | 2003-12-23 | 2020-07-21 | Boston Scientific Scimed, Inc. | Methods and apparatus for performing valvuloplasty |
US9872768B2 (en) | 2003-12-23 | 2018-01-23 | Boston Scientific Scimed, Inc. | Medical devices and delivery systems for delivering medical devices |
US10772724B2 (en) | 2003-12-23 | 2020-09-15 | Boston Scientific Scimed, Inc. | Medical devices and delivery systems for delivering medical devices |
US8579962B2 (en) | 2003-12-23 | 2013-11-12 | Sadra Medical, Inc. | Methods and apparatus for performing valvuloplasty |
US8603160B2 (en) | 2003-12-23 | 2013-12-10 | Sadra Medical, Inc. | Method of using a retrievable heart valve anchor with a sheath |
US9387076B2 (en) | 2003-12-23 | 2016-07-12 | Boston Scientific Scimed Inc. | Medical devices and delivery systems for delivering medical devices |
US8623078B2 (en) | 2003-12-23 | 2014-01-07 | Sadra Medical, Inc. | Replacement valve and anchor |
US10925724B2 (en) | 2003-12-23 | 2021-02-23 | Boston Scientific Scimed, Inc. | Replacement valve and anchor |
US9861476B2 (en) | 2003-12-23 | 2018-01-09 | Boston Scientific Scimed Inc. | Leaflet engagement elements and methods for use thereof |
US8828078B2 (en) | 2003-12-23 | 2014-09-09 | Sadra Medical, Inc. | Methods and apparatus for endovascular heart valve replacement comprising tissue grasping elements |
US8246678B2 (en) | 2003-12-23 | 2012-08-21 | Sadra Medicl, Inc. | Methods and apparatus for endovascularly replacing a patient's heart valve |
US8623076B2 (en) | 2003-12-23 | 2014-01-07 | Sadra Medical, Inc. | Low profile heart valve and delivery system |
US9393113B2 (en) | 2003-12-23 | 2016-07-19 | Boston Scientific Scimed Inc. | Retrievable heart valve anchor and method |
US20060173524A1 (en) * | 2003-12-23 | 2006-08-03 | Amr Salahieh | Medical Implant Delivery And Deployment Tool |
US9011521B2 (en) | 2003-12-23 | 2015-04-21 | Sadra Medical, Inc. | Methods and apparatus for endovascularly replacing a patient's heart valve |
US9005273B2 (en) | 2003-12-23 | 2015-04-14 | Sadra Medical, Inc. | Assessing the location and performance of replacement heart valves |
US8840662B2 (en) | 2003-12-23 | 2014-09-23 | Sadra Medical, Inc. | Repositionable heart valve and method |
US8840663B2 (en) | 2003-12-23 | 2014-09-23 | Sadra Medical, Inc. | Repositionable heart valve method |
US8858620B2 (en) | 2003-12-23 | 2014-10-14 | Sadra Medical Inc. | Methods and apparatus for endovascularly replacing a heart valve |
US9526609B2 (en) | 2003-12-23 | 2016-12-27 | Boston Scientific Scimed, Inc. | Methods and apparatus for endovascularly replacing a patient's heart valve |
US8894703B2 (en) | 2003-12-23 | 2014-11-25 | Sadra Medical, Inc. | Systems and methods for delivering a medical implant |
US11185408B2 (en) | 2003-12-23 | 2021-11-30 | Boston Scientific Scimed, Inc. | Methods and apparatus for endovascular heart valve replacement comprising tissue grasping elements |
US9585750B2 (en) | 2003-12-23 | 2017-03-07 | Boston Scientific Scimed, Inc. | Methods and apparatus for endovascularly replacing a patient's heart valve |
US9585749B2 (en) | 2003-12-23 | 2017-03-07 | Boston Scientific Scimed, Inc. | Replacement heart valve assembly |
US11278398B2 (en) | 2003-12-23 | 2022-03-22 | Boston Scientific Scimed, Inc. | Methods and apparatus for endovascular heart valve replacement comprising tissue grasping elements |
US8951299B2 (en) | 2003-12-23 | 2015-02-10 | Sadra Medical, Inc. | Medical devices and delivery systems for delivering medical devices |
US7824443B2 (en) | 2003-12-23 | 2010-11-02 | Sadra Medical, Inc. | Medical implant delivery and deployment tool |
US9532872B2 (en) | 2003-12-23 | 2017-01-03 | Boston Scientific Scimed, Inc. | Systems and methods for delivering a medical implant |
US8668733B2 (en) | 2004-06-16 | 2014-03-11 | Sadra Medical, Inc. | Everting heart valve |
US9744035B2 (en) | 2004-06-16 | 2017-08-29 | Boston Scientific Scimed, Inc. | Everting heart valve |
US11484405B2 (en) | 2004-06-16 | 2022-11-01 | Boston Scientific Scimed, Inc. | Everting heart valve |
US8992608B2 (en) | 2004-06-16 | 2015-03-31 | Sadra Medical, Inc. | Everting heart valve |
US8328868B2 (en) | 2004-11-05 | 2012-12-11 | Sadra Medical, Inc. | Medical devices and delivery systems for delivering medical devices |
US10531952B2 (en) | 2004-11-05 | 2020-01-14 | Boston Scientific Scimed, Inc. | Medical devices and delivery systems for delivering medical devices |
US8617236B2 (en) | 2004-11-05 | 2013-12-31 | Sadra Medical, Inc. | Medical devices and delivery systems for delivering medical devices |
US9775705B2 (en) | 2005-01-20 | 2017-10-03 | Jenavalve Technology, Inc. | Methods of implanting an endoprosthesis |
US9788945B2 (en) | 2005-01-20 | 2017-10-17 | Jenavalve Technology, Inc. | Systems for implanting an endoprosthesis |
US11517431B2 (en) | 2005-01-20 | 2022-12-06 | Jenavalve Technology, Inc. | Catheter system for implantation of prosthetic heart valves |
US10492906B2 (en) | 2005-01-20 | 2019-12-03 | Jenavalve Technology, Inc. | Catheter system for implantation of prosthetic heart valves |
US8679174B2 (en) | 2005-01-20 | 2014-03-25 | JenaValve Technology, GmbH | Catheter for the transvascular implantation of prosthetic heart valves |
US10549101B2 (en) | 2005-04-25 | 2020-02-04 | Cardiac Pacemakers, Inc. | Method and apparatus for pacing during revascularization |
US9415225B2 (en) | 2005-04-25 | 2016-08-16 | Cardiac Pacemakers, Inc. | Method and apparatus for pacing during revascularization |
US9649495B2 (en) | 2005-04-25 | 2017-05-16 | Cardiac Pacemakers, Inc. | Method and apparatus for pacing during revascularization |
US9827095B2 (en) | 2005-05-27 | 2017-11-28 | Hlt, Inc. | Stentless support structure |
US9439760B2 (en) | 2005-05-27 | 2016-09-13 | Hlt, Inc. | Stentless support structure |
US9271831B2 (en) | 2005-05-27 | 2016-03-01 | Hlt, Inc. | Stentless support structure |
US20060271166A1 (en) * | 2005-05-27 | 2006-11-30 | Heart Leaflet Technologies, Inc. | Stentless support structure |
US8974523B2 (en) * | 2005-05-27 | 2015-03-10 | Hlt, Inc. | Stentless support structure |
US9814575B2 (en) | 2005-05-27 | 2017-11-14 | Hlt, Inc. | Stentless support structure |
US10646337B2 (en) | 2005-05-27 | 2020-05-12 | Hlt, Inc. | Stentless support structure |
US11026784B2 (en) | 2005-05-27 | 2021-06-08 | Hlt, Inc. | Stentless support structure |
US9168132B2 (en) | 2005-05-27 | 2015-10-27 | Hlt, Inc. | Stentless support structure |
US10080655B2 (en) | 2005-05-27 | 2018-09-25 | Hlt, Inc. | Stentless support structure |
US9180002B2 (en) | 2005-05-27 | 2015-11-10 | Hlt, Inc. | Stentless support structure |
US9393094B2 (en) | 2005-09-13 | 2016-07-19 | Boston Scientific Scimed, Inc. | Two-part package for medical implant |
US10370150B2 (en) | 2005-09-13 | 2019-08-06 | Boston Scientific Scimed Inc. | Two-part package for medical implant |
US8136659B2 (en) | 2005-09-13 | 2012-03-20 | Sadra Medical, Inc. | Two-part package for medical implant |
USRE45790E1 (en) | 2005-10-28 | 2015-11-03 | Jenavalve Technology Gmbh | Device for the implantation and fixation of prosthetic valves |
US11116628B2 (en) | 2005-10-28 | 2021-09-14 | Jenavalve Technology, Inc. | Device for the implantation and fixation of prosthetic valves |
US10363134B2 (en) | 2005-10-28 | 2019-07-30 | Jenavalve Technology, Inc. | Device for the implantation and fixation of prosthetic valves |
US8834561B2 (en) | 2005-10-28 | 2014-09-16 | Jenavalve Technology Gmbh | Device for the implantation and fixation of prosthetic valves |
US9044320B2 (en) | 2005-10-28 | 2015-06-02 | Jenavalve Technology Gmbh | Device for the implantation and fixation of prosthetic valves |
US9855142B2 (en) | 2005-10-28 | 2018-01-02 | JenaValve Technologies, Inc. | Device for the implantation and fixation of prosthetic valves |
US9402717B2 (en) | 2005-10-28 | 2016-08-02 | Jenavalve Technology, Inc. | Device for the implantation and fixation of prosthetic valves |
USRE45962E1 (en) | 2005-10-28 | 2016-04-05 | Jenavalve Technology Gmbh | Device for the implantation and fixation of prosthetic valves |
US8287584B2 (en) | 2005-11-14 | 2012-10-16 | Sadra Medical, Inc. | Medical implant deployment tool |
US10314701B2 (en) | 2005-12-22 | 2019-06-11 | Symetis Sa | Stent-valves for valve replacement and associated methods and systems for surgery |
US10265167B2 (en) | 2005-12-22 | 2019-04-23 | Symetis Sa | Stent-valves for valve replacement and associated methods and systems for surgery |
US10299922B2 (en) | 2005-12-22 | 2019-05-28 | Symetis Sa | Stent-valves for valve replacement and associated methods and systems for surgery |
US9839515B2 (en) | 2005-12-22 | 2017-12-12 | Symetis, SA | Stent-valves for valve replacement and associated methods and systems for surgery |
US20190008637A1 (en) * | 2007-04-13 | 2019-01-10 | Jenavalve Technology, Inc. | Medical device for treating a heart valve insufficiency |
US11357624B2 (en) | 2007-04-13 | 2022-06-14 | Jenavalve Technology, Inc. | Medical device for treating a heart valve insufficiency |
US7914575B2 (en) | 2007-04-13 | 2011-03-29 | Jenavalve Technology, Inc. | Medical device for treating a heart valve insufficiency |
US9918835B2 (en) | 2007-04-13 | 2018-03-20 | Jenavalve Technology, Inc. | Medical device for treating a heart valve insufficency |
US8685085B2 (en) | 2007-04-13 | 2014-04-01 | JenaValve Technologies GmbH | Medical device for treating a heart valve insufficiency |
US9339386B2 (en) | 2007-04-13 | 2016-05-17 | Jenavalve Technology, Inc. | Medical device for treating a heart valve insufficency |
US9295551B2 (en) | 2007-04-13 | 2016-03-29 | Jenavalve Technology Gmbh | Methods of implanting an endoprosthesis |
US10543084B2 (en) * | 2007-04-13 | 2020-01-28 | Jenavalve Technology, Inc. | Medical device for treating a heart valve insufficiency |
US9254192B2 (en) | 2007-09-13 | 2016-02-09 | Georg Lutter | Truncated cone heart valve stent |
US10456248B2 (en) | 2007-09-13 | 2019-10-29 | Georg Lutter | Truncated cone heart valve stent |
US9078749B2 (en) | 2007-09-13 | 2015-07-14 | Georg Lutter | Truncated cone heart valve stent |
US9095433B2 (en) | 2007-09-13 | 2015-08-04 | Georg Lutter | Truncated cone heart valve stent |
US11213387B2 (en) | 2007-09-13 | 2022-01-04 | Georg Lutter | Truncated cone heart valve stent |
US9730792B2 (en) | 2007-09-13 | 2017-08-15 | Georg Lutter | Truncated cone heart valve stent |
US20090210047A1 (en) * | 2008-02-18 | 2009-08-20 | Aga Medical Corporation | Stent graft for reinforcement of vascular abnormalities and associated method |
US8163004B2 (en) * | 2008-02-18 | 2012-04-24 | Aga Medical Corporation | Stent graft for reinforcement of vascular abnormalities and associated method |
US9168130B2 (en) | 2008-02-26 | 2015-10-27 | Jenavalve Technology Gmbh | Stent for the positioning and anchoring of a valvular prosthesis in an implantation site in the heart of a patient |
US8790395B2 (en) | 2008-02-26 | 2014-07-29 | Jenavalve Technology Gmbh | Stent for the positioning and anchoring of a valvular prosthesis in an implantation site in the heart of a patient |
US10154901B2 (en) | 2008-02-26 | 2018-12-18 | Jenavalve Technology, Inc. | Stent for the positioning and anchoring of a valvular prosthesis in an implantation site in the heart of a patient |
US9867699B2 (en) | 2008-02-26 | 2018-01-16 | Jenavalve Technology, Inc. | Endoprosthesis for implantation in the heart of a patient |
US8398704B2 (en) | 2008-02-26 | 2013-03-19 | Jenavalve Technology, Inc. | Stent for the positioning and anchoring of a valvular prosthesis in an implantation site in the heart of a patient |
US9044318B2 (en) | 2008-02-26 | 2015-06-02 | Jenavalve Technology Gmbh | Stent for the positioning and anchoring of a valvular prosthesis |
US8317858B2 (en) | 2008-02-26 | 2012-11-27 | Jenavalve Technology, Inc. | Stent for the positioning and anchoring of a valvular prosthesis in an implantation site in the heart of a patient |
US11564794B2 (en) | 2008-02-26 | 2023-01-31 | Jenavalve Technology, Inc. | Stent for the positioning and anchoring of a valvular prosthesis in an implantation site in the heart of a patient |
US9439759B2 (en) | 2008-02-26 | 2016-09-13 | Jenavalve Technology, Inc. | Endoprosthesis for implantation in the heart of a patient |
US9707075B2 (en) | 2008-02-26 | 2017-07-18 | Jenavalve Technology, Inc. | Endoprosthesis for implantation in the heart of a patient |
US8465540B2 (en) | 2008-02-26 | 2013-06-18 | Jenavalve Technology, Inc. | Stent for the positioning and anchoring of a valvular prosthesis |
US9877828B2 (en) | 2008-02-26 | 2018-01-30 | Jenavalve Technology, Inc. | Stent for the positioning and anchoring of a valvular prosthesis in an implantation site in the heart of a patient |
US10702382B2 (en) | 2008-02-26 | 2020-07-07 | Jenavalve Technology, Inc. | Stent for the positioning and anchoring of a valvular prosthesis in an implantation site in the heart of a patient |
US10993805B2 (en) | 2008-02-26 | 2021-05-04 | Jenavalve Technology, Inc. | Stent for the positioning and anchoring of a valvular prosthesis in an implantation site in the heart of a patient |
US9265631B2 (en) | 2008-02-26 | 2016-02-23 | Jenavalve Technology, Inc. | Stent for the positioning and anchoring of a valvular prosthesis in an implantation site in the heart of a patient |
US10575947B2 (en) | 2008-02-26 | 2020-03-03 | Jenavalve Technology, Inc. | Stent for the positioning and anchoring of a valvular prosthesis in an implantation site in the heart of a patient |
US11154398B2 (en) | 2008-02-26 | 2021-10-26 | JenaValve Technology. Inc. | Stent for the positioning and anchoring of a valvular prosthesis in an implantation site in the heart of a patient |
US9987133B2 (en) | 2008-02-26 | 2018-06-05 | Jenavalve Technology, Inc. | Stent for the positioning and anchoring of a valvular prosthesis in an implantation site in the heart of a patient |
US8323335B2 (en) | 2008-06-20 | 2012-12-04 | Edwards Lifesciences Corporation | Retaining mechanisms for prosthetic valves and methods for using |
US8236049B2 (en) | 2008-06-20 | 2012-08-07 | Edwards Lifesciences Corporation | Multipiece prosthetic mitral valve and method |
US9339377B2 (en) | 2008-09-29 | 2016-05-17 | Edwards Lifesciences Cardiaq Llc | Body cavity prosthesis |
US9456896B2 (en) | 2008-09-29 | 2016-10-04 | Edwards Lifesciences Cardiaq Llc | Body cavity prosthesis |
US9597183B2 (en) | 2008-10-01 | 2017-03-21 | Edwards Lifesciences Cardiaq Llc | Delivery system for vascular implant |
US9301840B2 (en) | 2008-10-10 | 2016-04-05 | Edwards Lifesciences Corporation | Expandable introducer sheath |
US9339378B2 (en) | 2009-04-15 | 2016-05-17 | Edwards Lifesciences Cardiaq Llc | Vascular implant and delivery system |
US9339380B2 (en) | 2009-04-15 | 2016-05-17 | Edwards Lifesciences Cardiaq Llc | Vascular implant |
US9333073B2 (en) | 2009-04-15 | 2016-05-10 | Edwards Lifesciences Cardiaq Llc | Vascular implant and delivery method |
US9333074B2 (en) | 2009-04-15 | 2016-05-10 | Edwards Lifesciences Cardiaq Llc | Vascular implant and delivery system |
US9339379B2 (en) | 2009-04-15 | 2016-05-17 | Edwards Lifesciences Cardiaq Llc | Vascular implant and delivery system |
US9585747B2 (en) | 2009-04-15 | 2017-03-07 | Edwards Lifesciences Cardiaq Llc | Vascular implant |
US8468667B2 (en) | 2009-05-15 | 2013-06-25 | Jenavalve Technology, Inc. | Device for compressing a stent |
US11628060B2 (en) | 2009-11-05 | 2023-04-18 | The Trustees Of The University Of Pennsylvania | Valve prosthesis |
US9289291B2 (en) | 2009-11-05 | 2016-03-22 | The Trustees Of The University Of Pennsylvania | Valve prosthesis |
US11864993B2 (en) | 2009-11-05 | 2024-01-09 | The Trustees Of The University Of Pennsylvania | Valve prosthesis |
US20110137397A1 (en) * | 2009-12-04 | 2011-06-09 | Edwards Lifesciences Corporation | Prosthetic valve for replacing mitral valve |
US9717591B2 (en) | 2009-12-04 | 2017-08-01 | Edwards Lifesciences Corporation | Prosthetic valve for replacing mitral valve |
US8926691B2 (en) | 2009-12-04 | 2015-01-06 | Edwards Lifesciences Corporation | Apparatus for treating a mitral valve |
US8449599B2 (en) | 2009-12-04 | 2013-05-28 | Edwards Lifesciences Corporation | Prosthetic valve for replacing mitral valve |
US9084676B2 (en) | 2009-12-04 | 2015-07-21 | Edwards Lifesciences Corporation | Apparatus for treating a mitral valve |
US9433500B2 (en) | 2009-12-04 | 2016-09-06 | Edwards Lifesciences Corporation | Prosthetic valve for replacing mitral valve |
US8986373B2 (en) | 2009-12-04 | 2015-03-24 | Edwards Lifesciences Corporation | Method for implanting a prosthetic mitral valve |
US11179236B2 (en) | 2009-12-08 | 2021-11-23 | Colorado State University Research Foundation | Device and system for transcatheter mitral valve replacement |
US11918461B2 (en) | 2010-03-05 | 2024-03-05 | Edwards Lifesciences Corporation | Methods for treating a deficient native mitral valve |
US10568736B2 (en) | 2010-03-05 | 2020-02-25 | Edward Lifesciences Corporation | Retaining mechanisms for prosthetic valves |
US20110218620A1 (en) * | 2010-03-05 | 2011-09-08 | Edwards Lifesciences Corporation | Retaining Mechanisms for Prosthetic Valves |
US10130464B2 (en) | 2010-03-05 | 2018-11-20 | Edwards Lifesciences Corporation | Retaining mechanisms for prosthetic valves |
US8398708B2 (en) | 2010-03-05 | 2013-03-19 | Edwards Lifesciences Corporation | Retaining mechanisms for prosthetic valves |
US11890187B2 (en) | 2010-03-05 | 2024-02-06 | Edwards Lifesciences Corporation | Retaining mechanisms for prosthetic valves |
US9370420B2 (en) | 2010-03-05 | 2016-06-21 | Edwards Lifesciences Corporation | Retaining mechanisms for prosthetic valves |
US11419720B2 (en) | 2010-05-05 | 2022-08-23 | Neovasc Tiara Inc. | Transcatheter mitral valve prosthesis |
US11432924B2 (en) | 2010-05-05 | 2022-09-06 | Neovasc Tiara Inc. | Transcatheter mitral valve prosthesis |
US9770329B2 (en) | 2010-05-05 | 2017-09-26 | Neovasc Tiara Inc. | Transcatheter mitral valve prosthesis |
US10449042B2 (en) | 2010-05-05 | 2019-10-22 | Neovasc Tiara Inc. | Transcatheter mitral valve prosthesis |
US11147669B2 (en) | 2010-05-20 | 2021-10-19 | Jenavalve Technology, Inc. | Catheter system for introducing an expandable stent into the body of a patient |
US10307251B2 (en) | 2010-05-20 | 2019-06-04 | Jenavalve Technology, Inc. | Catheter system for introducing an expandable stent into the body of a patient |
US11278406B2 (en) | 2010-05-20 | 2022-03-22 | Jenavalve Technology, Inc. | Catheter system for introducing an expandable heart valve stent into the body of a patient, insertion system with a catheter system and medical device for treatment of a heart valve defect |
US10856978B2 (en) | 2010-05-20 | 2020-12-08 | Jenavalve Technology, Inc. | Catheter system |
US9597182B2 (en) | 2010-05-20 | 2017-03-21 | Jenavalve Technology Inc. | Catheter system for introducing an expandable stent into the body of a patient |
US10603164B2 (en) | 2010-05-25 | 2020-03-31 | Jenavalve Technology, Inc. | Prosthetic heart valve and endoprosthesis comprising a prosthetic heart valve and a stent |
US9744031B2 (en) | 2010-05-25 | 2017-08-29 | Jenavalve Technology, Inc. | Prosthetic heart valve and endoprosthesis comprising a prosthetic heart valve and a stent |
US11589981B2 (en) | 2010-05-25 | 2023-02-28 | Jenavalve Technology, Inc. | Prosthetic heart valve and transcatheter delivered endoprosthesis comprising a prosthetic heart valve and a stent |
US11311377B2 (en) | 2010-07-09 | 2022-04-26 | Highlife Sas | Transcatheter atrio-ventricular valve prosthesis |
US11446140B2 (en) | 2010-07-09 | 2022-09-20 | Highlife Sas | Transcatheter atrio-ventricular valve prosthesis |
US11883283B2 (en) | 2010-07-09 | 2024-01-30 | Highlife Sas | Transcatheter atrio-ventricular valve prosthesis |
US9931206B2 (en) | 2010-07-09 | 2018-04-03 | Highlife Sas | Transcatheter atrio-ventricular valve prosthesis |
US11259922B2 (en) | 2010-07-09 | 2022-03-01 | Highlife Sas | Transcatheter atrio-ventricular valve prosthesis |
US9375312B2 (en) | 2010-07-09 | 2016-06-28 | Highlife Sas | Transcatheter atrio-ventricular valve prosthesis |
US11259921B2 (en) | 2010-07-09 | 2022-03-01 | Highlife Sas | Transcatheter atrio-ventricular valve prosthesis |
US9326853B2 (en) | 2010-07-23 | 2016-05-03 | Edwards Lifesciences Corporation | Retaining mechanisms for prosthetic valves |
US9801711B2 (en) | 2010-08-11 | 2017-10-31 | Hlt, Inc. | Reinforced commissural support structure |
US10201418B2 (en) | 2010-09-10 | 2019-02-12 | Symetis, SA | Valve replacement devices, delivery device for a valve replacement device and method of production of a valve replacement device |
US10869760B2 (en) | 2010-09-10 | 2020-12-22 | Symetis Sa | Valve replacement devices, delivery device for a valve replacement device and method of production of a valve replacement device |
CN103517688A (en) * | 2011-01-11 | 2014-01-15 | 汉斯·赖纳·菲古拉 | Valve prosthesis for replacing an atrioventricular valve of the heart |
US11931252B2 (en) * | 2011-03-21 | 2024-03-19 | Cephea Valve Technologies, Inc. | Disk-based valve apparatus and method for the treatment of valve dysfunction |
US10456255B2 (en) | 2011-03-21 | 2019-10-29 | Cephea Valve Technologies, Inc. | Disk-based valve apparatus and method for the treatment of valve dysfunction |
US8728155B2 (en) | 2011-03-21 | 2014-05-20 | Cephea Valve Technologies, Inc. | Disk-based valve apparatus and method for the treatment of valve dysfunction |
US9713529B2 (en) | 2011-04-28 | 2017-07-25 | Neovasc Tiara Inc. | Sequentially deployed transcatheter mitral valve prosthesis |
US9554897B2 (en) | 2011-04-28 | 2017-01-31 | Neovasc Tiara Inc. | Methods and apparatus for engaging a valve prosthesis with tissue |
US11771544B2 (en) | 2011-05-05 | 2023-10-03 | Symetis Sa | Method and apparatus for compressing/loading stent-valves |
US9522064B2 (en) | 2011-05-16 | 2016-12-20 | Hlt, Inc. | Inversion delivery device and method for a prosthesis |
US11413143B2 (en) | 2011-05-16 | 2022-08-16 | Hlt, Inc. | Inversion delivery device and method for a prosthesis |
US10188517B2 (en) | 2011-05-16 | 2019-01-29 | Hlt, Inc. | Inversion delivery device and method for a prosthesis |
US9566154B2 (en) | 2011-05-16 | 2017-02-14 | Hlt, Inc. | Inversion delivery device and method for a prosthesis |
US10278817B2 (en) | 2011-05-16 | 2019-05-07 | Hlt, Inc. | Inversion delivery device and method for a prosthesis |
US9693863B2 (en) | 2011-05-16 | 2017-07-04 | Hlt, Inc. | Inversion delivery device and method for a prosthesis |
US9795478B2 (en) | 2011-05-16 | 2017-10-24 | Hlt, Inc. | Inversion delivery device and method for a prosthesis |
US9271832B2 (en) | 2011-05-16 | 2016-03-01 | Hlt, Inc. | Inversion delivery device and method for a prosthesis |
WO2012178115A3 (en) * | 2011-06-24 | 2013-02-21 | Rosenbluth, Robert | Percutaneously implantable artificial heart valve system and associated methods and devices |
US8998976B2 (en) | 2011-07-12 | 2015-04-07 | Boston Scientific Scimed, Inc. | Coupling system for medical devices |
US9480559B2 (en) | 2011-08-11 | 2016-11-01 | Tendyne Holdings, Inc. | Prosthetic valves and related inventions |
US10639145B2 (en) | 2011-08-11 | 2020-05-05 | Tendyne Holdings, Inc. | Prosthetic valves and related inventions |
US11382737B2 (en) | 2011-08-11 | 2022-07-12 | Tendyne Holdings, Inc. | Prosthetic valves and related inventions |
US11311374B2 (en) | 2011-08-11 | 2022-04-26 | Tendyne Holdings, Inc. | Prosthetic valves and related inventions |
US11123180B2 (en) | 2011-08-11 | 2021-09-21 | Tendyne Holdings, Inc. | Prosthetic valves and related inventions |
US11123181B2 (en) | 2011-08-11 | 2021-09-21 | Tendyne Holdings, Inc. | Prosthetic valves and related inventions |
US11135055B2 (en) | 2011-08-11 | 2021-10-05 | Tendyne Holdings, Inc. | Prosthetic valves and related inventions |
US11364116B2 (en) | 2011-08-11 | 2022-06-21 | Tendyne Holdings, Inc. | Prosthetic valves and related inventions |
US11484404B2 (en) | 2011-08-11 | 2022-11-01 | Tendyne Holdings, Inc. | Prosthetic valves and related inventions |
US10617519B2 (en) | 2011-08-11 | 2020-04-14 | Tendyne Holdings, Inc. | Prosthetic valves and related inventions |
US9833315B2 (en) | 2011-08-11 | 2017-12-05 | Tendyne Holdings, Inc. | Prosthetic valves and related inventions |
US9510947B2 (en) | 2011-10-21 | 2016-12-06 | Jenavalve Technology, Inc. | Catheter system for introducing an expandable heart valve stent into the body of a patient |
US9131926B2 (en) | 2011-11-10 | 2015-09-15 | Boston Scientific Scimed, Inc. | Direct connect flush system |
US9555219B2 (en) | 2011-11-10 | 2017-01-31 | Boston Scientific Scimed, Inc. | Direct connect flush system |
US10478300B2 (en) | 2011-11-15 | 2019-11-19 | Boston Scientific Scimed, Inc. | Bond between components of a medical device |
US8940014B2 (en) | 2011-11-15 | 2015-01-27 | Boston Scientific Scimed, Inc. | Bond between components of a medical device |
US9642705B2 (en) | 2011-11-15 | 2017-05-09 | Boston Scientific Scimed Inc. | Bond between components of a medical device |
US11413139B2 (en) | 2011-11-23 | 2022-08-16 | Neovasc Tiara Inc. | Sequentially deployed transcatheter mitral valve prosthesis |
US10537422B2 (en) | 2011-11-23 | 2020-01-21 | Neovasc Tiara Inc. | Sequentially deployed transcatheter mitral valve prosthesis |
US8951243B2 (en) | 2011-12-03 | 2015-02-10 | Boston Scientific Scimed, Inc. | Medical device handle |
US9370421B2 (en) | 2011-12-03 | 2016-06-21 | Boston Scientific Scimed, Inc. | Medical device handle |
US10952844B2 (en) | 2011-12-16 | 2021-03-23 | Tendyne Holdings, Inc. | Tethers for prosthetic mitral valve |
US9827092B2 (en) | 2011-12-16 | 2017-11-28 | Tendyne Holdings, Inc. | Tethers for prosthetic mitral valve |
US9510945B2 (en) | 2011-12-20 | 2016-12-06 | Boston Scientific Scimed Inc. | Medical device handle |
US9277993B2 (en) | 2011-12-20 | 2016-03-08 | Boston Scientific Scimed, Inc. | Medical device delivery systems |
US10172708B2 (en) | 2012-01-25 | 2019-01-08 | Boston Scientific Scimed, Inc. | Valve assembly with a bioabsorbable gasket and a replaceable valve implant |
US10363133B2 (en) | 2012-02-14 | 2019-07-30 | Neovac Tiara Inc. | Methods and apparatus for engaging a valve prosthesis with tissue |
US11497602B2 (en) | 2012-02-14 | 2022-11-15 | Neovasc Tiara Inc. | Methods and apparatus for engaging a valve prosthesis with tissue |
US9878127B2 (en) | 2012-05-16 | 2018-01-30 | Jenavalve Technology, Inc. | Catheter delivery system for heart valve prosthesis |
US10016275B2 (en) | 2012-05-30 | 2018-07-10 | Neovasc Tiara Inc. | Methods and apparatus for loading a prosthesis onto a delivery system |
US10314705B2 (en) | 2012-05-30 | 2019-06-11 | Neovasc Tiara Inc. | Methods and apparatus for loading a prosthesis onto a delivery system |
US11389294B2 (en) | 2012-05-30 | 2022-07-19 | Neovasc Tiara Inc. | Methods and apparatus for loading a prosthesis onto a delivery system |
US10940001B2 (en) | 2012-05-30 | 2021-03-09 | Neovasc Tiara Inc. | Methods and apparatus for loading a prosthesis onto a delivery system |
US11617650B2 (en) | 2012-05-30 | 2023-04-04 | Neovasc Tiara Inc. | Methods and apparatus for loading a prosthesis onto a delivery system |
US11382739B2 (en) | 2012-06-19 | 2022-07-12 | Boston Scientific Scimed, Inc. | Replacement heart valve |
US10555809B2 (en) | 2012-06-19 | 2020-02-11 | Boston Scientific Scimed, Inc. | Replacement heart valve |
US9895221B2 (en) | 2012-07-28 | 2018-02-20 | Tendyne Holdings, Inc. | Multi-component designs for heart valve retrieval device, sealing structures and stent assembly |
US11759318B2 (en) | 2012-07-28 | 2023-09-19 | Tendyne Holdings, Inc. | Multi-component designs for heart valve retrieval device, sealing structures and stent assembly |
US11090155B2 (en) | 2012-07-30 | 2021-08-17 | Tendyne Holdings, Inc. | Delivery systems and methods for transcatheter prosthetic valves |
US10219900B2 (en) | 2012-07-30 | 2019-03-05 | Tendyne Holdings, Inc. | Delivery systems and methods for transcatheter prosthetic valves |
US9675454B2 (en) | 2012-07-30 | 2017-06-13 | Tendyne Holdings, Inc. | Delivery systems and methods for transcatheter prosthetic valves |
US9907652B2 (en) | 2012-09-06 | 2018-03-06 | Edwards Lifesciences Corporation | Heart valve sealing devices |
US9414918B2 (en) | 2012-09-06 | 2016-08-16 | Edwards Lifesciences Corporation | Heart valve sealing devices |
US9510946B2 (en) | 2012-09-06 | 2016-12-06 | Edwards Lifesciences Corporation | Heart valve sealing devices |
US10016276B2 (en) | 2012-11-21 | 2018-07-10 | Edwards Lifesciences Corporation | Retaining mechanisms for prosthetic heart valves |
US11234819B2 (en) | 2012-11-21 | 2022-02-01 | Edwards Lifesciences Corporation | Retaining mechanisms for prosthetic heart valves |
US10463481B2 (en) | 2013-02-04 | 2019-11-05 | Edwards Lifesciences Corporation | Prosthetic valve for replacing mitral valve |
US10799347B1 (en) | 2013-02-04 | 2020-10-13 | Edwards Lifesciences Corporation | Prosthetic heart valve with atrial sealing member |
US9439763B2 (en) | 2013-02-04 | 2016-09-13 | Edwards Lifesciences Corporation | Prosthetic valve for replacing mitral valve |
US10583002B2 (en) | 2013-03-11 | 2020-03-10 | Neovasc Tiara Inc. | Prosthetic valve with anti-pivoting mechanism |
US9681951B2 (en) | 2013-03-14 | 2017-06-20 | Edwards Lifesciences Cardiaq Llc | Prosthesis with outer skirt and anchors |
US9486314B2 (en) | 2013-03-15 | 2016-11-08 | Hlt, Inc. | Low-profile prosthetic valve structure |
US9931205B2 (en) | 2013-03-15 | 2018-04-03 | Hlt, Inc. | Low-profile prosthetic valve structure |
US9486306B2 (en) | 2013-04-02 | 2016-11-08 | Tendyne Holdings, Inc. | Inflatable annular sealing device for prosthetic mitral valve |
US11224510B2 (en) | 2013-04-02 | 2022-01-18 | Tendyne Holdings, Inc. | Prosthetic heart valve and systems and methods for delivering the same |
US10463489B2 (en) | 2013-04-02 | 2019-11-05 | Tendyne Holdings, Inc. | Prosthetic heart valve and systems and methods for delivering the same |
US10463494B2 (en) | 2013-04-02 | 2019-11-05 | Tendyne Holdings, Inc. | Prosthetic heart valve and systems and methods for delivering the same |
US11311379B2 (en) | 2013-04-02 | 2022-04-26 | Tendyne Holdings, Inc. | Prosthetic heart valve and systems and methods for delivering the same |
US9572665B2 (en) | 2013-04-04 | 2017-02-21 | Neovasc Tiara Inc. | Methods and apparatus for delivering a prosthetic valve to a beating heart |
US10383728B2 (en) | 2013-04-04 | 2019-08-20 | Neovasc Tiara Inc. | Methods and apparatus for delivering a prosthetic valve to a beating heart |
US11389291B2 (en) | 2013-04-04 | 2022-07-19 | Neovase Tiara Inc. | Methods and apparatus for delivering a prosthetic valve to a beating heart |
US11364119B2 (en) | 2013-04-04 | 2022-06-21 | Tendyne Holdings, Inc. | Retrieval and repositioning system for prosthetic heart valve |
US10478293B2 (en) | 2013-04-04 | 2019-11-19 | Tendyne Holdings, Inc. | Retrieval and repositioning system for prosthetic heart valve |
US10405976B2 (en) | 2013-05-30 | 2019-09-10 | Tendyne Holdings, Inc. | Structural members for prosthetic mitral valves |
US11617645B2 (en) | 2013-05-30 | 2023-04-04 | Tendyne Holdings, Inc. | Structural members for prosthetic mitral valves |
US9610159B2 (en) | 2013-05-30 | 2017-04-04 | Tendyne Holdings, Inc. | Structural members for prosthetic mitral valves |
US10022213B2 (en) | 2013-06-14 | 2018-07-17 | Avantec Vascular Corporation | Shaping improvements for Inferior Vena Cava filter and retrieval systems |
US9949816B2 (en) | 2013-06-14 | 2018-04-24 | Avantec Vascular Corporation | IVC filter retrieval systems with multiple capture modes |
US11051926B2 (en) | 2013-06-14 | 2021-07-06 | Avantec Vascular Corporation | Method for retrieval of a medical device |
US11013589B2 (en) | 2013-06-14 | 2021-05-25 | Avantec Vascular Corporation | Method for IVC filter retrieval with multiple capture modes |
US11219517B2 (en) | 2013-06-14 | 2022-01-11 | Avantec Vascular Corporation | Inferior Vena Cava filter and retrieval systems |
US11471281B2 (en) | 2013-06-25 | 2022-10-18 | Tendyne Holdings, Inc. | Thrombus management and structural compliance features for prosthetic heart valves |
US9597181B2 (en) | 2013-06-25 | 2017-03-21 | Tendyne Holdings, Inc. | Thrombus management and structural compliance features for prosthetic heart valves |
US10595996B2 (en) | 2013-06-25 | 2020-03-24 | Tendyne Holdings, Inc. | Thrombus management and structural compliance features for prosthetic heart valves |
US9259237B2 (en) | 2013-07-12 | 2016-02-16 | Inceptus Medical, Llc | Methods and apparatus for treating pulmonary embolism |
US9561103B2 (en) * | 2013-07-17 | 2017-02-07 | Cephea Valve Technologies, Inc. | System and method for cardiac valve repair and replacement |
US10624742B2 (en) | 2013-07-17 | 2020-04-21 | Cephea Valve Technologies, Inc. | System and method for cardiac valve repair and replacement |
US10154906B2 (en) | 2013-07-17 | 2018-12-18 | Cephea Valve Technologies, Inc. | System and method for cardiac valve repair and replacement |
US10149761B2 (en) | 2013-07-17 | 2018-12-11 | Cephea Valve Technlologies, Inc. | System and method for cardiac valve repair and replacement |
US11510780B2 (en) | 2013-07-17 | 2022-11-29 | Cephea Valve Technologies, Inc. | System and method for cardiac valve repair and replacement |
US20150025623A1 (en) * | 2013-07-17 | 2015-01-22 | Juan F. Granada | System and method for cardiac valve repair and replacement |
US8870948B1 (en) | 2013-07-17 | 2014-10-28 | Cephea Valve Technologies, Inc. | System and method for cardiac valve repair and replacement |
US9554899B2 (en) | 2013-07-17 | 2017-01-31 | Cephea Valve Technologies, Inc. | System and method for cardiac valve repair and replacement |
US11612480B2 (en) | 2013-08-01 | 2023-03-28 | Tendyne Holdings, Inc. | Epicardial anchor devices and methods |
US10610354B2 (en) | 2013-08-01 | 2020-04-07 | Tendyne Holdings, Inc. | Epicardial anchor devices and methods |
US11185405B2 (en) | 2013-08-30 | 2021-11-30 | Jenavalve Technology, Inc. | Radially collapsible frame for a prosthetic valve and method for manufacturing such a frame |
US9867694B2 (en) | 2013-08-30 | 2018-01-16 | Jenavalve Technology Inc. | Radially collapsible frame for a prosthetic valve and method for manufacturing such a frame |
US10433954B2 (en) | 2013-08-30 | 2019-10-08 | Jenavalve Technology, Inc. | Radially collapsible frame for a prosthetic valve and method for manufacturing such a frame |
US11690716B2 (en) | 2013-09-10 | 2023-07-04 | Edwards Lifesciences Corporation | Method for delivering a support member to a native heart valve |
US10195028B2 (en) | 2013-09-10 | 2019-02-05 | Edwards Lifesciences Corporation | Magnetic retaining mechanisms for prosthetic valves |
US11103347B2 (en) | 2013-09-10 | 2021-08-31 | Edwards Lifesciences Corporation | Magnetic retaining mechanisms for prosthetic valves |
US11246562B2 (en) | 2013-10-17 | 2022-02-15 | Tendyne Holdings, Inc. | Apparatus and methods for alignment and deployment of intracardiac devices |
US10555718B2 (en) | 2013-10-17 | 2020-02-11 | Tendyne Holdings, Inc. | Apparatus and methods for alignment and deployment of intracardiac devices |
US9526611B2 (en) | 2013-10-29 | 2016-12-27 | Tendyne Holdings, Inc. | Apparatus and methods for delivery of transcatheter prosthetic valves |
US10363135B2 (en) | 2013-10-29 | 2019-07-30 | Tendyne Holdings, Inc. | Apparatus and methods for delivery of transcatheter prosthetic valves |
US11096783B2 (en) | 2013-10-29 | 2021-08-24 | Tendyne Holdings, Inc. | Apparatus and methods for delivery of transcatheter prosthetic valves |
US10201419B2 (en) | 2014-02-05 | 2019-02-12 | Tendyne Holdings, Inc. | Apparatus and methods for transfemoral delivery of prosthetic mitral valve |
US11464628B2 (en) | 2014-02-05 | 2022-10-11 | Tendyne Holdings, Inc. | Expandable epicardial pads and devices and methods for delivery of same |
US11589985B2 (en) | 2014-02-05 | 2023-02-28 | Tendyne Holdings, Inc. | Apparatus and methods for transfemoral delivery of prosthetic mitral valve |
US9986993B2 (en) | 2014-02-11 | 2018-06-05 | Tendyne Holdings, Inc. | Adjustable tether and epicardial pad system for prosthetic heart valve |
US11045183B2 (en) | 2014-02-11 | 2021-06-29 | Tendyne Holdings, Inc. | Adjustable tether and epicardial pad system for prosthetic heart valve |
CN106456325A (en) * | 2014-02-28 | 2017-02-22 | 高品质生活简化股份公司 | Transcatheter valve prosthesis |
US10517728B2 (en) | 2014-03-10 | 2019-12-31 | Tendyne Holdings, Inc. | Devices and methods for positioning and monitoring tether load for prosthetic mitral valve |
US11382753B2 (en) | 2014-03-10 | 2022-07-12 | Tendyne Holdings, Inc. | Devices and methods for positioning and monitoring tether load for prosthetic mitral valve |
US9532870B2 (en) | 2014-06-06 | 2017-01-03 | Edwards Lifesciences Corporation | Prosthetic valve for replacing a mitral valve |
US10195026B2 (en) | 2014-07-22 | 2019-02-05 | Edwards Lifesciences Corporation | Mitral valve anchoring |
US20210128300A1 (en) | 2014-08-21 | 2021-05-06 | Edwards Lifesciences Corporation | Dual-flange prosthetic valve frame |
US11826252B2 (en) | 2014-08-21 | 2023-11-28 | Edwards Lifesciences Corporation | Dual-flange prosthetic valve frame |
US10881512B2 (en) | 2014-08-21 | 2021-01-05 | Edwards Lifesciences Corporation | Dual-flange prosthetic valve frame |
US10058424B2 (en) | 2014-08-21 | 2018-08-28 | Edwards Lifesciences Corporation | Dual-flange prosthetic valve frame |
US9999504B2 (en) | 2014-10-13 | 2018-06-19 | Hlt, Inc. | Inversion delivery device and method for a prosthesis |
US10820995B2 (en) | 2014-10-13 | 2020-11-03 | Hlt, Inc. | Inversion delivery device and method for a prosthesis |
US9901445B2 (en) | 2014-11-21 | 2018-02-27 | Boston Scientific Scimed, Inc. | Valve locking mechanism |
US10548721B2 (en) | 2014-12-09 | 2020-02-04 | Cephea Valve Technologies, Inc. | Replacement cardiac valves and methods of use and manufacture |
US9439757B2 (en) | 2014-12-09 | 2016-09-13 | Cephea Valve Technologies, Inc. | Replacement cardiac valves and methods of use and manufacture |
US9492273B2 (en) | 2014-12-09 | 2016-11-15 | Cephea Valve Technologies, Inc. | Replacement cardiac valves and methods of use and manufacture |
US10869755B2 (en) | 2014-12-09 | 2020-12-22 | Cephea Valve Technologies, Inc. | Replacement cardiac valves and methods of use and manufacture |
US11147665B2 (en) | 2014-12-09 | 2021-10-19 | Cepha Valve Technologies, Inc. | Replacement cardiac valves and methods of use and manufacture |
US10433953B2 (en) | 2014-12-09 | 2019-10-08 | Cephea Valve Technologies, Inc. | Replacement cardiac valves and methods of use and manufacture |
US10856962B2 (en) | 2014-12-12 | 2020-12-08 | Avantec Vascular Corporation | IVC filter retrieval systems with interposed support members |
US10278804B2 (en) | 2014-12-12 | 2019-05-07 | Avantec Vascular Corporation | IVC filter retrieval systems with releasable capture feature |
US11903810B2 (en) | 2014-12-12 | 2024-02-20 | Avantec Vascular Corporation | Instrument for delivery or capture of a medical device in a blood vessel |
US10786351B2 (en) | 2015-01-07 | 2020-09-29 | Tendyne Holdings, Inc. | Prosthetic mitral valves and apparatus and methods for delivery of same |
US10449043B2 (en) | 2015-01-16 | 2019-10-22 | Boston Scientific Scimed, Inc. | Displacement based lock and release mechanism |
US9861477B2 (en) | 2015-01-26 | 2018-01-09 | Boston Scientific Scimed Inc. | Prosthetic heart valve square leaflet-leaflet stitch |
US9788942B2 (en) | 2015-02-03 | 2017-10-17 | Boston Scientific Scimed Inc. | Prosthetic heart valve having tubular seal |
US10201417B2 (en) | 2015-02-03 | 2019-02-12 | Boston Scientific Scimed Inc. | Prosthetic heart valve having tubular seal |
US10610356B2 (en) | 2015-02-05 | 2020-04-07 | Tendyne Holdings, Inc. | Expandable epicardial pads and devices and methods for delivery of same |
US10426617B2 (en) | 2015-03-06 | 2019-10-01 | Boston Scientific Scimed, Inc. | Low profile valve locking mechanism and commissure assembly |
US10285809B2 (en) | 2015-03-06 | 2019-05-14 | Boston Scientific Scimed Inc. | TAVI anchoring assist device |
US11065113B2 (en) | 2015-03-13 | 2021-07-20 | Boston Scientific Scimed, Inc. | Prosthetic heart valve having an improved tubular seal |
US10080652B2 (en) | 2015-03-13 | 2018-09-25 | Boston Scientific Scimed, Inc. | Prosthetic heart valve having an improved tubular seal |
US10010417B2 (en) | 2015-04-16 | 2018-07-03 | Edwards Lifesciences Corporation | Low-profile prosthetic heart valve for replacing a mitral valve |
US11523902B2 (en) | 2015-04-16 | 2022-12-13 | Tendyne Holdings, Inc. | Apparatus and methods for delivery, repositioning, and retrieval of transcatheter prosthetic valves |
US10667905B2 (en) | 2015-04-16 | 2020-06-02 | Tendyne Holdings, Inc. | Apparatus and methods for delivery, repositioning, and retrieval of transcatheter prosthetic valves |
US10624736B2 (en) | 2015-04-16 | 2020-04-21 | Edwards Lifesciences Corporation | Low-profile prosthetic heart valve for replacing a mitral valve |
US10064718B2 (en) | 2015-04-16 | 2018-09-04 | Edwards Lifesciences Corporation | Low-profile prosthetic heart valve for replacing a mitral valve |
US10709555B2 (en) | 2015-05-01 | 2020-07-14 | Jenavalve Technology, Inc. | Device and method with reduced pacemaker rate in heart valve replacement |
US11337800B2 (en) | 2015-05-01 | 2022-05-24 | Jenavalve Technology, Inc. | Device and method with reduced pacemaker rate in heart valve replacement |
US10849746B2 (en) | 2015-05-14 | 2020-12-01 | Cephea Valve Technologies, Inc. | Cardiac valve delivery devices and systems |
US11786373B2 (en) | 2015-05-14 | 2023-10-17 | Cephea Valve Technologies, Inc. | Cardiac valve delivery devices and systems |
US10555808B2 (en) | 2015-05-14 | 2020-02-11 | Cephea Valve Technologies, Inc. | Replacement mitral valves |
US11617646B2 (en) | 2015-05-14 | 2023-04-04 | Cephea Valve Technologies, Inc. | Replacement mitral valves |
US10470881B2 (en) | 2015-05-14 | 2019-11-12 | Cephea Valve Technologies, Inc. | Replacement mitral valves |
US10143552B2 (en) | 2015-05-14 | 2018-12-04 | Cephea Valve Technologies, Inc. | Replacement mitral valves |
US11730595B2 (en) | 2015-07-02 | 2023-08-22 | Boston Scientific Scimed, Inc. | Adjustable nosecone |
US10195392B2 (en) | 2015-07-02 | 2019-02-05 | Boston Scientific Scimed, Inc. | Clip-on catheter |
US10335277B2 (en) | 2015-07-02 | 2019-07-02 | Boston Scientific Scimed Inc. | Adjustable nosecone |
US10179041B2 (en) | 2015-08-12 | 2019-01-15 | Boston Scientific Scimed Icn. | Pinless release mechanism |
US10856973B2 (en) | 2015-08-12 | 2020-12-08 | Boston Scientific Scimed, Inc. | Replacement heart valve implant |
US10136991B2 (en) | 2015-08-12 | 2018-11-27 | Boston Scientific Scimed Inc. | Replacement heart valve implant |
US10779940B2 (en) | 2015-09-03 | 2020-09-22 | Boston Scientific Scimed, Inc. | Medical device handle |
US10327894B2 (en) | 2015-09-18 | 2019-06-25 | Tendyne Holdings, Inc. | Methods for delivery of prosthetic mitral valves |
US11318012B2 (en) | 2015-09-18 | 2022-05-03 | Tendyne Holdings, Inc. | Apparatus and methods for delivery of prosthetic mitral valve |
US10470876B2 (en) | 2015-11-10 | 2019-11-12 | Edwards Lifesciences Corporation | Transcatheter heart valve for replacing natural mitral valve |
US10376364B2 (en) | 2015-11-10 | 2019-08-13 | Edwards Lifesciences Corporation | Implant delivery capsule |
US11096782B2 (en) | 2015-12-03 | 2021-08-24 | Tendyne Holdings, Inc. | Frame features for prosthetic mitral valves |
US10610358B2 (en) | 2015-12-28 | 2020-04-07 | Tendyne Holdings, Inc. | Atrial pocket closures for prosthetic heart valves |
US11464629B2 (en) | 2015-12-28 | 2022-10-11 | Tendyne Holdings, Inc. | Atrial pocket closures for prosthetic heart valves |
US10342660B2 (en) | 2016-02-02 | 2019-07-09 | Boston Scientific Inc. | Tensioned sheathing aids |
US10470877B2 (en) | 2016-05-03 | 2019-11-12 | Tendyne Holdings, Inc. | Apparatus and methods for anterior valve leaflet management |
US11253354B2 (en) | 2016-05-03 | 2022-02-22 | Tendyne Holdings, Inc. | Apparatus and methods for anterior valve leaflet management |
US10583005B2 (en) | 2016-05-13 | 2020-03-10 | Boston Scientific Scimed, Inc. | Medical device handle |
US11065138B2 (en) | 2016-05-13 | 2021-07-20 | Jenavalve Technology, Inc. | Heart valve prosthesis delivery system and method for delivery of heart valve prosthesis with introducer sheath and loading system |
US11382742B2 (en) | 2016-05-13 | 2022-07-12 | Boston Scientific Scimed, Inc. | Medical device handle |
US10245136B2 (en) | 2016-05-13 | 2019-04-02 | Boston Scientific Scimed Inc. | Containment vessel with implant sheathing guide |
US10709552B2 (en) | 2016-05-16 | 2020-07-14 | Boston Scientific Scimed, Inc. | Replacement heart valve implant with invertible leaflets |
US20170325938A1 (en) | 2016-05-16 | 2017-11-16 | Boston Scientific Scimed, Inc. | Replacement heart valve implant with invertible leaflets |
US10201416B2 (en) | 2016-05-16 | 2019-02-12 | Boston Scientific Scimed, Inc. | Replacement heart valve implant with invertible leaflets |
US11039921B2 (en) | 2016-06-13 | 2021-06-22 | Tendyne Holdings, Inc. | Sequential delivery of two-part prosthetic mitral valve |
US11331187B2 (en) | 2016-06-17 | 2022-05-17 | Cephea Valve Technologies, Inc. | Cardiac valve delivery devices and systems |
US11701226B2 (en) | 2016-06-30 | 2023-07-18 | Tendyne Holdings, Inc. | Prosthetic heart valves and apparatus and methods for delivery of same |
US11090157B2 (en) | 2016-06-30 | 2021-08-17 | Tendyne Holdings, Inc. | Prosthetic heart valves and apparatus and methods for delivery of same |
US11065116B2 (en) | 2016-07-12 | 2021-07-20 | Tendyne Holdings, Inc. | Apparatus and methods for trans-septal retrieval of prosthetic heart valves |
US9994980B2 (en) | 2016-10-14 | 2018-06-12 | Inceptus Medical, Llc | Braiding machine and methods of use |
US11898282B2 (en) | 2016-10-14 | 2024-02-13 | Inceptus Medical, Llc | Braiding machine and methods of use |
US10577733B2 (en) | 2016-10-14 | 2020-03-03 | Inceptus Medical, Llc | Braiding machine and methods of use |
US11346027B2 (en) | 2016-10-14 | 2022-05-31 | Inceptus Medical, Llc | Braiding machine and methods of use |
US10195027B2 (en) | 2016-11-04 | 2019-02-05 | Highlife Sas | Transcatheter valve prosthesis |
US9999502B2 (en) | 2016-11-04 | 2018-06-19 | Highlife Sas | Transcather valve prosthesis |
US10736739B2 (en) | 2016-11-04 | 2020-08-11 | Highlife Sas | Transcatheter valve prosthesis |
US10456247B2 (en) | 2016-11-04 | 2019-10-29 | Highlife Sas | Transcatheter valve prosthesis |
US11141266B2 (en) | 2016-11-04 | 2021-10-12 | Highlife Sas | Transcatheter valve prosthesis |
US10188514B2 (en) | 2016-11-04 | 2019-01-29 | Highlife Sas | Transcatheter valve prosthesis |
US11376121B2 (en) | 2016-11-04 | 2022-07-05 | Highlife Sas | Transcatheter valve prosthesis |
US10874499B2 (en) | 2016-12-22 | 2020-12-29 | Avantec Vascular Corporation | Systems, devices, and methods for retrieval systems having a tether |
US11833024B2 (en) | 2016-12-22 | 2023-12-05 | Avantec Vascular Corporation | Systems, devices, and methods for retrieval systems having a tether |
US10828153B2 (en) | 2017-01-23 | 2020-11-10 | Cephea Valve Technologies, Inc. | Replacement mitral valves |
US11633278B2 (en) | 2017-01-23 | 2023-04-25 | Cephea Valve Technologies, Inc. | Replacement mitral valves |
US10368990B2 (en) | 2017-01-23 | 2019-08-06 | Cephea Valve Technologies, Inc. | Replacement mitral valves |
US11058535B2 (en) | 2017-01-23 | 2021-07-13 | Cephea Valve Technologies, Inc. | Replacement mitral valves |
US11090158B2 (en) | 2017-01-23 | 2021-08-17 | Cephea Valve Technologies, Inc. | Replacement mitral valves |
US10568737B2 (en) | 2017-01-23 | 2020-02-25 | Cephea Valve Technologies, Inc. | Replacement mitral valves |
US11197754B2 (en) | 2017-01-27 | 2021-12-14 | Jenavalve Technology, Inc. | Heart valve mimicry |
US10660648B2 (en) | 2017-02-24 | 2020-05-26 | Inceptus Medical, Llc | Vascular occlusion devices and methods |
US11304701B2 (en) | 2017-02-24 | 2022-04-19 | Inceptus Medical, Llc | Vascular occlusion devices and methods |
US10376267B2 (en) | 2017-02-24 | 2019-08-13 | Inceptus Medical, Llc | Vascular occlusion devices and methods |
US10828154B2 (en) | 2017-06-08 | 2020-11-10 | Boston Scientific Scimed, Inc. | Heart valve implant commissure support structure |
US11154399B2 (en) | 2017-07-13 | 2021-10-26 | Tendyne Holdings, Inc. | Prosthetic heart valves and apparatus and methods for delivery of same |
US10898325B2 (en) | 2017-08-01 | 2021-01-26 | Boston Scientific Scimed, Inc. | Medical implant locking mechanism |
US10939996B2 (en) | 2017-08-16 | 2021-03-09 | Boston Scientific Scimed, Inc. | Replacement heart valve commissure assembly |
US11191639B2 (en) | 2017-08-28 | 2021-12-07 | Tendyne Holdings, Inc. | Prosthetic heart valves with tether coupling features |
US11885051B2 (en) | 2017-10-14 | 2024-01-30 | Inceptus Medical, Llc | Braiding machine and methods of use |
US11191641B2 (en) | 2018-01-19 | 2021-12-07 | Boston Scientific Scimed, Inc. | Inductance mode deployment sensors for transcatheter valve system |
US11246625B2 (en) | 2018-01-19 | 2022-02-15 | Boston Scientific Scimed, Inc. | Medical device delivery system with feedback loop |
US11147668B2 (en) | 2018-02-07 | 2021-10-19 | Boston Scientific Scimed, Inc. | Medical device delivery system with alignment feature |
US11439732B2 (en) | 2018-02-26 | 2022-09-13 | Boston Scientific Scimed, Inc. | Embedded radiopaque marker in adaptive seal |
US11229517B2 (en) | 2018-05-15 | 2022-01-25 | Boston Scientific Scimed, Inc. | Replacement heart valve commissure assembly |
US11241310B2 (en) | 2018-06-13 | 2022-02-08 | Boston Scientific Scimed, Inc. | Replacement heart valve delivery device |
US11833025B2 (en) | 2018-06-29 | 2023-12-05 | Avantec Vascular Corporation | Systems and methods for implants and deployment devices |
US11241312B2 (en) | 2018-12-10 | 2022-02-08 | Boston Scientific Scimed, Inc. | Medical device delivery system including a resistance member |
US11364030B2 (en) * | 2019-02-15 | 2022-06-21 | Boston Scientific Scimed, Inc. | Medical device for treating esophageal atresia |
US11439504B2 (en) | 2019-05-10 | 2022-09-13 | Boston Scientific Scimed, Inc. | Replacement heart valve with improved cusp washout and reduced loading |
US11648110B2 (en) | 2019-12-05 | 2023-05-16 | Tendyne Holdings, Inc. | Braided anchor for mitral valve |
US11648114B2 (en) | 2019-12-20 | 2023-05-16 | Tendyne Holdings, Inc. | Distally loaded sheath and loading funnel |
US11951002B2 (en) | 2020-03-30 | 2024-04-09 | Tendyne Holdings, Inc. | Apparatus and methods for valve and tether fixation |
US11678980B2 (en) | 2020-08-19 | 2023-06-20 | Tendyne Holdings, Inc. | Fully-transseptal apical pad with pulley for tensioning |
Also Published As
Publication number | Publication date |
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PL1942834T3 (en) | 2013-06-28 |
PT1942834E (en) | 2013-04-15 |
EP1942834A1 (en) | 2008-07-16 |
JP2009514628A (en) | 2009-04-09 |
AU2006310681B2 (en) | 2011-02-17 |
US20070142906A1 (en) | 2007-06-21 |
EP1942834B1 (en) | 2013-01-16 |
US8062355B2 (en) | 2011-11-22 |
CA2627555A1 (en) | 2007-05-10 |
AU2006310681A1 (en) | 2007-05-10 |
JP4904362B2 (en) | 2012-03-28 |
DK1942834T3 (en) | 2013-04-08 |
SI1942834T1 (en) | 2013-05-31 |
ES2401451T3 (en) | 2013-04-19 |
CA2627555C (en) | 2011-04-05 |
DE102005052628A1 (en) | 2007-05-10 |
DE102005052628B4 (en) | 2014-06-05 |
WO2007051620A1 (en) | 2007-05-10 |
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