US20070100455A1 - Method and apparatus for fixation of intervertebral disc prosthesis - Google Patents
Method and apparatus for fixation of intervertebral disc prosthesis Download PDFInfo
- Publication number
- US20070100455A1 US20070100455A1 US11/399,903 US39990306A US2007100455A1 US 20070100455 A1 US20070100455 A1 US 20070100455A1 US 39990306 A US39990306 A US 39990306A US 2007100455 A1 US2007100455 A1 US 2007100455A1
- Authority
- US
- United States
- Prior art keywords
- endplate
- intervertebral disc
- disc prosthesis
- prosthesis
- fixation surface
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/44—Joints for the spine, e.g. vertebrae, spinal discs
- A61F2/442—Intervertebral or spinal discs, e.g. resilient
- A61F2/4425—Intervertebral or spinal discs, e.g. resilient made of articulated components
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- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/46—Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor
- A61F2/4603—Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor for insertion or extraction of endoprosthetic joints or of accessories thereof
- A61F2/4611—Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor for insertion or extraction of endoprosthetic joints or of accessories thereof of spinal prostheses
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- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
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- A61B17/02—Surgical instruments, devices or methods, e.g. tourniquets for holding wounds open; Tractors
- A61B17/025—Joint distractors
- A61B2017/0256—Joint distractors for the spine
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- A61F2002/30004—Material related properties of the prosthesis or of a coating on the prosthesis the prosthesis being made from materials having different values of a given property at different locations within the same prosthesis
- A61F2002/30016—Material related properties of the prosthesis or of a coating on the prosthesis the prosthesis being made from materials having different values of a given property at different locations within the same prosthesis differing in hardness, e.g. Vickers, Shore, Brinell
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- A61F2002/3006—Properties of materials and coating materials
- A61F2002/30062—(bio)absorbable, biodegradable, bioerodable, (bio)resorbable, resorptive
- A61F2002/30064—Coating or prosthesis-covering structure made of biodegradable material
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Definitions
- FIG. 2 shows a side cross-sectional view of the intervertebral disc prosthesis of FIG. 1 ;
- FIG. 8 shows a cross-sectional view of the intervertebral disc prosthesis through line X-X of FIG. 5 ;
- FIG. 12 shows a perspective view of an alternative embodiment of the bottom surface of an endplate of the intervertebral disc prosthesis of FIG. 4 ;
- FIG. 12A shows a perspective view of an alternative embodiment of the intervertebral disc prosthesis of FIG. 4 including additional insertion features;
- FIG. 14A shows a cross-sectional view of an alternative embodiment of the intervertebral disc prosthesis of FIG. 4 having a core with an extended flange configured to limit motion;
- FIG. 18 shows a perspective view of an disc insertion tool for the intervertebral disc prosthesis of FIG. 4 in a retracted position
- FIG. 19 shows a perspective view of the disc insertion tool of FIG. 18 inserting the intervertebral disc prosthesis between vertebral bodies;
- the indentations are designed to allow the insertion/distraction instrument to hold the endplates and core of the prosthesis simultaneously to facilitate insertion of the prosthesis as a unitary assembled piece.
- the indentations take the form of notches 212 in the anterior corners on the left side 184 and right side 186 of the endplate 132 .
- the prongs of the insertion/distraction instrument grasp the surface of the endplate exposed by the notches 212 in order to hold the endplate and encourage the endplate toward the intervertebral space.
- the core 136 is a composite core comprised of a plurality of different portions made of different materials exhibiting different properties.
- FIGS. 15-17 show a plurality of different embodiments for a composite core comprising at least two materials with different properties, joined to form a single component.
- One embodiment of the composite core is a dual durometer core having a relatively soft bearing surface and a hardened flange.
- endplates 132 , 134 and core 136 various configurations and compositions are possible for the endplates 132 , 134 and core 136 .
- the surgeon may desire a specific endplate and core combination based on the particular needs of a patient. Therefore, the various endplates and cores are made available to the surgeon as part of a modular prosthesis system, where differing endplates may be matched with any number of different cores to arrive at the desired prosthesis. This provides the surgeon with a method of designing an intervertebral disc prosthesis that is customized to the needs of the particular patient.
Abstract
An intervertebral disc prosthesis comprises a superior endplate and an inferior endplate. The superior and inferior endplates include vertebra fixation surfaces designed to engage vertebral bodies. A composite material is provided on the vertebra fixation surfaces. The composite material includes an osteoconductive component and an osteoinductive component. The osteoconductive component provides a porous matrix or base that facilitates bone growth. The osteoinductive component provides a stimulant material that encourages growth of the bone cells between the osteoconductive component of the endplate and the vertebral body facing the endplate. In one embodiment, the osteoconductive component is permeated by an osteoinductive material to provide the composite material. In another embodiment, the composite material includes a non-resorbable portion that includes osteoconductive substances and a resorbable portion that is doped with osteoinductive substances.
Description
- This application is a continuation-in-part of U.S. patent application Ser. No. 11/264,471 filed Oct. 31, 2005.
- This invention relates to the field of prosthetics, and more particularly, to an intervertebral disc prosthesis designed to replace a damaged intervertebral disc.
- The human spine consists of twenty-four small bones known as vertebrae, or “vertebral bodies,” that protect the spinal cord and provide stability to the torso. The vertebrae are arranged in a column and stacked vertically upon each other. Between each vertebra is a fibrous bundle of tissue called an intervertebral disc. These intervertebral discs act as a cushion to the spinal column by absorbing energy and transmitting loads associated with everyday movement. They also prevent the vertebrae from rubbing against each other.
- Each intervertebral disc comprises two distinct regions. A firm outer region, the annulus, maintains the shape of the intervertebral disc. An inner region, the nucleus, provides a resilient tissue that enables the disc to function as a shock absorber. Over time, the normal aging process causes the intervertebral discs to degenerate, diminising their water content and thereby reducing their ability to properly absorb the impact associated with spinal movements. Diminished water content in the intervertebral discs may also cause the vertebrae to move closer together. Tears and scar tissue can weaken the discs, resulting in injury. When the discs wear out or are otherwise injured, a condition known as degenerative disc disease results. With this condition, discs do not function normally and may cause pain and limit activity.
- The condition of degenerative disc disease can potentially be relieved by a surgical procedure called artificial disc replacement. In this procedure, the damaged intervertebral disc is replaced by a prosthetic disc. One well known intervertebral prosthetic disc is produced by DePuy Spine, Inc. of Raynaham, Mass. and is sold under the trademark CHARITÉ®. This disc prosthesis is comprised of two metal endplates and a center polyethylene core. The center core includes a superior spherical bearing surface and an inferior spherical bearing surface. The superior endplate includes a concave surface that fits upon and is congruent with the superior bearing surface of the core. The inferior endplate includes a concave surface that fits under and is congruent with the inferior bearing surface of the core. During the CHARITÉ® artificial disc replacement procedure, the damaged disc is first removed via an anterior surgical approach and the end surfaces of the exposed vertebrae are cleared of debris. The vertebrae are spread apart and the metal endplates are positioned on the respective vertebra and tapped into place. The polyethylene core is then inserted between the endplates and the vertebrae are returned to their normal position. The pressure of the spinal column further seats the endplates into the vertebral bones and secures the core in place.
- Although current intervertebral disc prosthetic devices have enjoyed success, it would be beneficial to add additional desirable features to the prosthetic device. For example, it would be desirable to design the prosthetic device to provide improved fixation features to ensure attachment of the prosthetic device to the vertebral bodies. It would be particularly advantageous if such fixation features facilitated bony in-growth between the prosthetic device and the vertebral bodies, thus providing a secure and natural fixation of the prosthetic device to the vertebral bodies.
- An intervertebral disc prosthesis comprises a superior endplate and an inferior endplate. A bearing surface is positioned between the superior endplate and the inferior endplate such that the superior endplate is operable to pivot relative to the inferior endplate. The superior and inferior endplates include vertebra fixation surfaces designed to engage the vertebral bodies. The vertebra fixation surfaces are typically included on the faces of the endplates. For example, the vertebra fixation surfaces may be provided on a plurality of teeth found on the faces of the endplates.
- A textured surface is formed on each vertebra fixation surface. The textured surface provides a substrate that will accommodate bony in-growth between the endplate and the vertebral body. The surface texture on the teeth or other endplate surfaces may take any of several forms. In one embodiment, the texture is provided by an osteoconductive coating. The textured surface may also be provided by mechanical processes such as grinding or engraving, energy beam processes such as laser beam or electron beam, lithographical processes such as chemical lithography or electrochemical lithography, or other processes known in the art. The textured surface may be patterned or random and may include pockets, slots, grooves, indentations, bumps, or other texturing.
- The textured surface to provides a substrate for bone growth and attachment. An osteoinductive material is incorporated into or applied onto the substrate or the osteoconductive material to promote accumulation, attachment, and in-growth of the bone cells. Bony in-growth will result in a secure attachment between the endplate and the vertebral body.
- Provision of the textured surface may also be included as a composite material applied to the fixation surface of the endplate, wherein the composite material includes an osteoconductive component and an osteoinductive component. The osteoconductive component provides a porous matrix or base that facilitates bone attachment. The osteoinductive component provides a stimulant material that encourages growth of the bone cells between the osteoconductive component of the endplate and the vertebral body facing the endplate.
- In one embodiment, the osteoconductive component is soaked in or otherwise permeated by an osteoinductive material to provide the composite material. In another embodiment, the composite material includes a non-resorbable portion that includes osteoconductive substances and a resorbable portion that is doped with osteoinductive substances. The resorbable portion of the composite material is subject to dissolution in the body and essentially serves as a carrier designed to deliver a timed release of osteoinductive substances. As the resorbable component breaks down in the body, the osteoinductive substance is released and promotes bony ingrowth/attachment to the non-resorbable portion of the coating.
-
FIG. 1 shows an superior perspective view of an intervertebral disc prosthesis including a superior plate and a inferior plate separated by a core; -
FIG. 2 shows a side cross-sectional view of the intervertebral disc prosthesis ofFIG. 1 ; -
FIG. 3 shows a side cross-sectional view of the intervertebral disc prostheis ofFIG. 1 with the superior plate rotated to display flexion; -
FIG. 4 shows a perspective view of an alternative embodiment of the intervebral disc prosthesis ofFIG. 1 ; -
FIG. 5 shows a top plan view of the intervertebral disc prosthesis ofFIG. 4 including a top plan view of a superior plate of the intervertebral disc prosthesis; -
FIG. 6 shows a bottom plan view of the superior plate of the intervertebral disc prosthesis ofFIG. 5 , showing an articulation socket; -
FIG. 7 shows a right side elevational view of the superior plate of the intervebral disc prosthesis ofFIG. 5 ; -
FIG. 8 shows a cross-sectional view of the intervertebral disc prosthesis through line X-X ofFIG. 5 ; -
FIG. 9 shows a cross-sectional view of the intervertebral disc prosthesis through line XI-XI ofFIG. 5 ; -
FIG. 9A shows a cross-sectional view of an alternative embodiment of the intervebral disc prosthesis ofFIG. 9 ; -
FIG. 10 shows a bottom plan view of the superior plate ofFIG. 6 and its footprint in relation to a vertebral body; -
FIG. 11 shows a perspective view of an alternative embodiment of an endplate of the intervertebral disc prosthesis ofFIG. 4 ; -
FIG. 11A shows a perspective view of another alternative embodiment of the endplate ofFIG. 11 including a coating on the face of the endplate; -
FIG. 12 shows a perspective view of an alternative embodiment of the bottom surface of an endplate of the intervertebral disc prosthesis ofFIG. 4 ; -
FIG. 12A shows a perspective view of an alternative embodiment of the intervertebral disc prosthesis ofFIG. 4 including additional insertion features; -
FIG. 13 shows a perspective view of an alternative embodiment of the intervertebral disc prosthesis ofFIG. 4 ; -
FIG. 14A shows a cross-sectional view of an alternative embodiment of the intervertebral disc prosthesis ofFIG. 4 having a core with an extended flange configured to limit motion; -
FIG. 14B shows a cross-sectional view of an alternative embodiment of the intervertebral disc prosthesis ofFIG. 14A ; -
FIG. 15 shows a top view of an alternative embodiment of a core of the intervertebral disc prosthesis ofFIG. 4 ; -
FIG. 15A shows a cross-sectional view of the core ofFIG. 15 through line A-A; -
FIG. 16 shows a top view of another alternative embodiment of a core of the intervertebral disc prosthesis ofFIG. 4 ; -
FIG. 16A shows a cross-sectional view of the core ofFIG. 16 through line A-A; -
FIG. 17 shows a top view of yet another alternative embodiment of a core of the intervertebral disc prosthesis ofFIG. 4 ; -
FIG. 17A shows a cross-sectional view of the core ofFIG. 17 through line A-A; -
FIG. 17B shows a cross-sectional view of the core ofFIG. 17 through line B-B; -
FIG. 18 shows a perspective view of an disc insertion tool for the intervertebral disc prosthesis ofFIG. 4 in a retracted position; -
FIG. 19 shows a perspective view of the disc insertion tool ofFIG. 18 inserting the intervertebral disc prosthesis between vertebral bodies; -
FIG. 20 shows a perspective view of the disc insertion tool ofFIG. 18 in an extended position; -
FIG. 21 shows a top view of the intervertebral disc prosthesis ofFIG. 12A engaged with a disc insertion tool; and -
FIG. 22 shows a perspective view of the disc insertion tool ofFIG. 21 . - General Structure
- With reference to
FIGS. 1-3 , anintervertebral disc prosthesis 30 comprises asuperior plate 32, aninferior plate 34, and acore 36. Thecore 36 is sandwiched between thesuperior plate 32 and theinferior plate 34. Thesuperior plate 32 and theinferior plate 34 ride upon thecore 36 and are operable to rotate relative to the core. - The
superior plate 32 serves as a first endplate for theprosthetic device 30. In one embodiment, thesuperior plate 32 is comprised of metal. In particular, thesuperior plate 32 may be comprised of a medical grade cobalt chromium alloy. Thesuperior plate 32 comprises anupper surface 40 on one side and alower surface 42 on the other side. Anouter perimeter edge 44 defines the “footprint” shape of thesuperior plate 32. - The
upper surface 40 of thesuperior plate 32 is designed for engagement with a vertebral surface of a patient. To this end, theupper surface 40 of the superior plate may be slightly convex for close engagement with the slightly concave vertebral surface of the patient. A typical convexity of the superior plate is based on a 90-200 mm radius of curvature. The preferred convexity will vary from patient to patient, depending upon the size and vertebral surface shape of the patient. -
Teeth 46 are included on theupper surface 40 of thesuperior plate 32. Theteeth 46 are designed to penetrate into the vertebral surface, helping to secure thesuperior plate 32 to the vertebral surface. As explained in further detail below, certain advantages are achieved based on the positioning of the teeth on theplate 32, the size of theteeth 46, and the shape of the teeth. Screws (not shown) may also be threaded through holes (not shown) in the superior plate to provide further assistance in securing thesuperior plate 32 to the vertebral surface. - The
inferior surface 42 of thesuperior plate 32 is generally flat near theouter perimeter edge 44. However, with reference toFIGS. 2-3 , a donut-shapedcollar portion 48 depends from the center of theinferior surface 42 of theplate 32. An innerconcave surface 49 is provided at the center of thecollar portion 48. As explained in further detail below, this innerconcave surface 49 serves as a bearing surface/articulating surface for engagement with the core. As explained in further detail below, the bearing surfaces of the endplates and core together provide ball and socket joint arrangements for the prosthetic device. - The
inferior plate 34 is a mirror image of thesuperior plate 32 and is also made of a medical grade cobalt chromium alloy. Theinferior plate 34 includes a slightly convexinferior surface 50 outlined by anouter perimeter edge 54. A plurality ofteeth 56 extend from theinferior surface 50. Theteeth 56 are designed to help secure theinferior plate 34 to a vertebral surface. Theupper surface 52 of theinferior plate 34 includes acollar portion 58 with an innerconcave surface 59 which provides a bearing surface/articulating surface for engagement with the core. - The
prosthesis core 36 is sandwiched between thesuperior plate 32 and theinferior plate 34. Thecore 36 is arranged within an interior space of theprosthesis 30 defined between thelower surface 42 of thesuperior plate 32 and theupper surface 52 of theinferior plate 34. In one embodiment, theprosthesis core 36 is comprised of a plastic material having a high resistance to wear, such as ultra high molecular weight polyethylene (UHMWPE), which allows theendplates prosthesis core 36 is generally disc shaped with an outerradial flange 60, an upperspherical surface 62, and a lowerspherical surface 64. The upper spherical surface and lower spherical surface act as bearing surfaces/articulating surfaces that engage the bearing surfaces of theendplates FIG. 2 , afirst groove 66 is formed between theflange 60 and the superiorspherical surface 62. Asecond groove 68 is formed between theflange 60 and the inferiorspherical surface 64. - When the
prosthesis 30 is assembled, theconcave surface 49 of thesuperior plate 32 and the upperspherical surface 62 of the core 36 engage one another and form articular surfaces. Likewise, theconcave surface 59 of theinferior plate 34 and the lowerspherical surface 64 of the core 36 engage one another and form articular surfaces. - In one preferred embodiment, the
articular surfaces vertical axis 70. In this embodiment, the radii of the arcs in the frontal plane (i.e., the lateral bending plane) are equal to the radii of the arcs in the sagittal plane (i.e., flexion plane). This allows theplates core 36, including rotation in the transversal plane (i.e., torsional plane) while the articular surfaces remain in congruous contact. In this embodiment, thearticular surfaces - With reference to
FIG. 3 , theradial flange 60 and associatedgrooves superior plate 32 relative to theinferior plate 34 in the frontal and sagittal planes, theflange 60 of the prosthesis core engages thecollar portions endplates prosthesis 30. - Further Embodiments
- With reference to
FIG. 4 , an alternative embodiment of anintervertebral disc prosthesis 130 is shown. As shown inFIG. 4 , theprosthesis 130 comprises asuperior plate 132, aninferior plate 134 and acore 136 sandwiched between thesuperior plate 132 and theinferior plate 134. Thesuperior plate 132 is generally symmetric to theinferior plate 134. The plates are configured to include ananterior side 180, aposterior side 182, aleft side 184, and aright side 186. - The “footprint” of each
endplate FIG. 10 . With reference toFIGS. 5, 6 and 10, theleft side 184 of thesuperior endplate 132 is generally straight/flat and parallel to theright side 186 of theplate 132. Theanterior side 180 of theendplate 132 is generally arched and provides a curved edge that extends from theleft side 184 to theright side 186 of theendplate 132. Theanterior edge 180 of theendplate 132 provides an arch defined by a radius of curvature ranging from 10 to 40 mm. - The
posterior side 182 of the endplate includes three angled edges that give the endplate a trapezoidal appearance. In particular, theposterior side 182 of theendplate 132 includes arear edge 178, aleft bevel 174, and aright bevel 176. Theleft bevel 174 joins therear edge 178 to theleft edge 184 and theright bevel 176 joins therear edge 178 to theright edge 186. Theleft bevel 174 is substantially straight and extends between therear edge 178 and theleft edge 184 at a 45° angle relative to the rear edge. Likewise, theright bevel 176 is substantially straight and extends between therear edge 178 and theright edge 178 at a 45° angle relative to the rear edge. Therear edge 178 is generally perpendicular to theright edge 186 and leftedge 184. - As shown in
FIG. 10 , the above-described endplate footprint allows the endplate to substantially conform to thevertebral body 200 of the patient. In particular, the endplate footprint covers a substantial portion of the vertebral body, thus providing additional surface area for connection and bony in-growth between the endplate and the vertebral body. This in-growth may be facilitated by a porous bony in-growth coating on the endplates. - In addition to the above, each
endplate prosthesis 130 is slightly convex for close engagement with the slightly concave vertebral surface of the patient. A typical convexity of the superior plate is based on a 90-200 mm radius of curvature. The preferred convexity will vary from patient to patient, depending upon the patient's size and vertebral surface shape. - Endplate Teeth and Fixation Features
- As shown in
FIGS. 4 and 5 , theteeth 146 of theendplates outer surface 140 of the endplate (i.e., the upper surface of the superior endplate). The triangular base is an acute triangle with two of the triangular sides significantly longer than the triangular side opposite thevertex 190 of the triangular base. This results in pyramidal shaped teeth having twoelongated faces endplates vertex 190 of each triangular base pointed toward a central portion of the endplate. Theteeth 146 are also generally positioned toward theleft side 184 andright side 186 of the endplates. The radial arrangement of theteeth 146 on the left and right sides of the endplate results in the elongated faces 192 and 194 of the teeth directed generally toward the anterior or posterior sides of the endplates (i.e., anterior-posterior faces). - Each pyramidal shaped
tooth 146 may be further defined by a width and a height. The width of thetooth 146 is generally defined as the distance between thevertex 190 of the triangular base and the opposing side of the triangular base on the surface of the endplate. The height of the tooth is generally defined as the perpendicular distance from thepyramidal vertex 196 of thetooth 146 to the face of the endplate. The teeth shown inFIGS. 4 and 5 are broad teeth having a width that is greater than their height. This generally short yet broad tooth structure allows theprosthesis 130 to be more easily inserted into the intervertebral space than those prosthetic devices with longer teeth. This tooth structure also results in broad antero-posterior faces. The broad antero-posterior faces provide significant resistance to migration and antero-posterior shear/expulsion once the prosthetic device is in place in the intervertebral space. The radial arrangement of the teeth provides resistance to lateral shear and rotation relative to the vertebral bodies. - Another alternative embodiment of the teeth is shown in
FIG. 13 . The teeth ofFIG. 13 include two elongatedradial teeth 246 and two elongatedcircumferential teeth 248. The radial teeth are wedge shaped and extend laterally from right to left near the lateral midline of the prosthesis. Each radial tooth includes an elongatedanterior face 250 and an elongated posterior face (not shown). Thecircumferential teeth 248 bisect theradial teeth 246 as they extend circumferentially upon the face of the endplate. Thecircumferential teeth 248 are also wedge shaped. Eachcircumferential tooth 248 includes anexterior face 254 and aninterior face 256. Together, theradial teeth 246 andcircumferential teeth 248 form cross-shaped teeth on the left side and the right side of each endplate face. The teeth are relatively short and broad, allowing the intervertebral prosthesis to be more easily inserted in the intervertebral space. In addition, the cross-shaped tooth arrangement is configured to provide significant resistance to migration of the endplates once the intervertebral prosthesis is positioned in a patient. - In addition to the above features, the teeth may include a textured surface that will accommodate bony in-growth between the endplate and the vertebral body. However, the use of a textured surface on the endplate is not limited to the teeth. Textured surfaces may be provided on other portions of the endplate where bony in-growth is desirable. For example, as shown in
FIG. 11A , theface 140 of theendplate 132 includes atextured portion 147 designed to contact a vertebra. - The surface texture on the teeth or other endplate surfaces may take any of several forms. In one embodiment, the texture is provided by a coating of titanium, hydroxyapatite (HA), calcium phosphate, an osteoconductive matrix of cross-linked collagen fibers coated with hydroxyapatite (such as that sold under the trademark Healos®), or other osteoconductive materials as are known in the art. Such osteoconductive materials and/or coatings generally provide a porous substrate capable of accommodating bone growth and attachment. Osteoconductive coatings may be applied by a physical packing, brush, spray, chemical vapor deposition, physical vapor deposition, electrochemical deposition, or other methods as are known in the art. Alternatively, the textured surface may be provided by mechanical processes such as grinding or engraving, energy beam processes such as laser beam or electron beam, lithographical processes such as chemical lithography or electrochemical lithography, or other processes known in the art. The textured surface may be patterned or random and may include pockets, slots, grooves, indentations, bumps, or other texturing. As used herein, the term “textured surface” generally refers to a surface where texturing is intentionally formed on a surface using an osteoconductive coating, mechanical process, lithographical process, energy beam process, or other process. However, the term “textured surface” as used herein does not refer to the microscopic texture inherent to a surface that is not otherwise intentionally formed on the surface.
- The faces 192 and 194 of the teeth generally provide a good surface area where a textured surface capable of accommodating bone growth may be formed. However, as mentioned above, other surfaces on the endplate are also appropriate for a textured surface, such as
textured portion 147 on theendplate 132 ofFIG. 11A . - Bony in-growth will result in a secure attachment between the endplate and the vertebral body. Bone morphogenetic protein (BMP), bone marrow, stem cells or other osteoinductive material is used as the stimulant to promote bony in-growth. The osteoinductive material can be incorporated into or applied onto the endplate or the osteoconductive material. This combination of an osteoinductive material in association with an osteoconductive material on the surface of the endplate provides a desirable setting for bony in-growth. In one embodiment, an osteoconductive coating is provided as a first coating on the vertebra fixation surface of the endplate. An osteoinductive material is then applied as a second coating over the first coating of osteoconductive material. The osteoinductive material provides a stimulant material that encourages growth of the bone cells between the osteoconductive coating of the endplate and the vertebral body facing the endplate.
- In another embodiment, a coating of a composite material is applied to the vertebra fixation surface, wherein the composite material includes an osteoconductive component incorporated with an osteoinductive component. For example, a composite material including an osteoconductive component and an osteoinductive component may be provided by Healos® soaked in or otherwise permeated with BMP or bone marrow. In this example, the Healos® provides the osteoconductive material/component and the BMP or bone marrow provides the osteoinductive material/component. The Healos® is soaked in the BMP or bone marrow before application to the vertebra fixation surface of the endplate. After the Healos® is soaked in BMP (or bone marrow) the soaked material may be cut to a desired size and/or configuration for proper placement on the vertebra fixation surface. The soaked Healos® is then packed in a textured surface formed on the endplate, such as pockets or grooves on the anterior/posterior faces of the teeth or other vertebra fixation surface. While this embodiment has been described with reference to Healos® soaked in BMP or bone marrow, it should be recognized that other osteoconductive materials may soaked with the same or different osteoinductive materials to prepare the material to be packed on the vertebra fixation surface. In addition, it should be recognized that the osteoconductive material could actually be packed on the endplate before the osteoconductive material is soaked in the osteoinductive material.
- In addition to the above, other coatings of composite materials having osteoinductive and osteoconductive properties may be provided. For example, in one embodiment the composite material includes a non-resorbable portion that includes osteoconductive substances and a resorbable carrier portion that is doped with osteoinductive substances. The resorbable portion of the composite material is subject to dissolution in the body and essentially serves as a carrier designed to deliver a timed release of osteoinductive substances.
- Examples of materials that may be used as the non-resorbable portion of such composite material include titanium, metal matrix composite (MMC), ceramic or combinations thereof. Such osteoconductive substances serve as a porous matrix or base to which the resorbable carrier adheres. Examples of materials that may be used as the resorbable carrier portion include calcium phosphate, hydroxyapatite, collagen, mineralized collagen, biodegradable polyglycolic acid (PGA), polylactic acid (PLA), hydrogels, or combinations thereof. As mentioned above, the resorbable carrier portion is doped or impregnated with an osteoinductive substance, such as BMP, the patient's bone marrow, stem cell concentrates, or combinations thereof. As the resorbable component breaks down in the body, the osteoinductive substance impregnated in the resorbable component is released, promoting bony ingrowth and attachment to the non-resorble portion of the coating.
- Posterior Center of Rotation
-
FIG. 6 shows a plan view of thelower surface 142 of thesuperior plate 132 of one embodiment of theintervertebral disc prosthesis 130. As shown inFIG. 6 , a donut-shapedcollar portion 148 is included on thelower surface 142 of theupper plate 132. Thecollar 148 extends outward from other portions of thelower surface 142 and surrounds a semi-sphericalconcave surface 149 that provides a socket for thecore 136 of the prosthesis. Theconcave surface 149 defines a center-of-rotation for thesuperior plate 132 relative to thecore 136. The position of the center of rotation is shown inFIG. 6 by a “+” 120. Also shown inFIG. 6 is alateral midline 122 extending laterally across theplate 132 from theleft side 184 to theright side 186. Thelateral midline 122 is a line located directly between the furthermost anterior edge and the furthermost posterior edge of theendplate 132. - As shown in
FIG. 6 , theradial collar 148 is centered upon theplate 132 such that it is closer to theposterior edge 182 than theanterior edge 180 of the plate. As a result, the center ofrotation 120 of thesuperior plate 132 is positioned to the posterior of thelateral midline 122. In particular, the center ofrotation 120 is located a distance “d” behind thelateral midline 122. In a preferred embodiment, the center of rotation is about 1 mm to 3 mm posterior to the lateral midline. This posterior center of rotation arrangement closely mimics the true anatomy of healthy vertebral bodies and intervertebral discs. - Insertion Features
- With continued reference to
FIGS. 4-7 , theendplates prosthesis 130 to be more easily inserted into the intervertebral space. For example, as best seen inFIG. 7 , theposterior side 182 of theendplate 132 is bulleted such that therear edge 176,left bevel 174, andright bevel 176 are all tapered and provide a generally pointed edge. This tapered edge on theposterior side 182 of endplate allows the endplate to be more easily inserted into a collapsed intervertebral space if an anterior approach is taken when inserting theprosthesis 130. In particular, the taperedrear edge 176 provides a bulleted surface to help wedge the prosthesis in the intervertebral space. In addition, theleft edge 184 andright edge 186 are tapered. These tapered edges further allow the endplate to be more easily inserted into a collapsed intervertebral space if a lateral approach is taken when inserting theprosthesis 130. - While the
posterior side 182 of theprosthesis 130 is tapered, theanterior side 180 is more flat and blunt. As explained in further detail below, thisblunt side 180 provides a flat anterior surface that may be pressed upon as the endplate is forced into the intervertebral space during insertion from an anterior approach. - In addition to the above, the
prosthesis 130 includes a central channel/slot 202 formed on the face of thesuperior plate 132, as shown inFIGS. 4 and 5 . Thecentral channel 202 is formed by aleft side rail 204 and aright side rail 206 that extend above the face of the superior plate from theanterior side 180 to theposterior side 182 and define the sides of thecentral channel 202. As explained in further detail below, the central channel is designed to engage a distracting ramp provided by an insertion arm of on an disc insertion tool, thus facilitating insertion of the prosthesis device into the intervertebral disc space. - In one alternative embodiment, the
central channel 202 may be defined by oblique rails or lateral rails that extend across the face of thesuperior plate 130 at 45° or 90° angles with respect to therails FIGS. 4 and 5 . Such oblique rails or lateral rails would facilitate oblique or lateral insertion of theintervertebral disc prosthesis 130. - In yet another alternative embodiment, the central channel may be embedded in the face of the endplate, such as that shown in
FIG. 11 . In this embodiment, thecentral channel 202 is defined by a left side rail embedded in the face of the plate to form aleft side wall 205. Likewise the right side rail is embedded in the face such that it forms aright side wall 207. Thecentral channel 202 gradually ramps deeper into the face of the endplate from the anterior to the posterior. In this embodiment, the endplate itself becomes gradually thicker from theanterior side 180 to theposterior side 182 of the endplate. This allows the endplate to incorporate a lordotic angle in the sagittal plane of the prosthesis. For example, if each endplate incorporates a 3.5° angle from anterior to posterior, the intervertebral prosthesis as a whole will incorporate a 7° lordotic angle in the sagittal plane. Endplates incorporating such a lordotic angle may desirable for certain patients. - Another feature designed to assist with insertion of the prosthesis device are retention surfaces in the form of indentations positioned on the endplates, such as grooves, notches, cavities, channels, crevices, or other recesses. As best seen in
FIGS. 4, 8 and 9, in one embodiment, the retention surfaces take the form ofgrooves 210 formed by thecollar 148 of the endplate. Thegrooves 210 are dimensioned to receive and engage prongs or “retaining arms” of the disc insertion tool, allowing the endplate to be retained by the instrument during insertion, as explained in further detail below. Preferably, the indentations are designed to allow the insertion/distraction instrument to hold the endplates and core of the prosthesis simultaneously to facilitate insertion of the prosthesis as a unitary assembled piece. In an alternative embodiment, such as that shown inFIG. 12 , the indentations take the form ofnotches 212 in the anterior corners on theleft side 184 andright side 186 of theendplate 132. In this embodiment, the prongs of the insertion/distraction instrument grasp the surface of the endplate exposed by thenotches 212 in order to hold the endplate and encourage the endplate toward the intervertebral space. - Another feature of the
intervertebral prosthesis 130 are lateral holding features, such as notches, holes, grooves, indentations, protrusions or other structural features that provide an easy means of grasping the endplates or theintervertebral prosthesis 130 in general. Examples of lateral holding features include thehole 220 in the central channel ofFIG. 13 and thenotches 212 in thelower surface 142 ofplate 132 inFIG. 12 . These lateral holding features facilitate non-anterior insertion of theintervertebral prosthesis 130 and non-anterior revision/retrieval of the prosthesis. In particular, the lateral holding features provide structural components that may be easily grasped by instrumentation that may be used to properly orient theprosthesis 130 during implantation or help retract an implanted prosthesis. Alternatively, thegroove 210 formed in thecollar 148 of the endplate could be a circumferential groove, such that an instrument could attach to this groove from any direction, including anterior, lateral, or posterior surgical approaches. An example of an embodiment with the circumferential groove is shown inFIG. 12A . - With reference to
FIG. 12A , an alternative embodiment of theintervertebral disc prosthesis 130 includes additional insertion features. In particular, ananti-rotation notch 218 is provided in both thesuperior plate 132 and theinferior plate 134. Theanti-rotation notch 218 takes the form of a semi-cylindrical notch carved in theanterior edge 181 of the endplate, extending from the upper surface of the endplate to the lower surface of the endplate. As explained in further detail below, the anti-rotation notch is designed to engage a peg on the disc insertion tool, and prevent rotation of thedisc 130 during the insertion process. - As also shown in
FIG. 12A , theintervertebral disc prosthesis 130 may include a spring-arm detent 222 formed in eachendplate spring arm detent 222 is formed in thelower surface 142 of thesuperior plate 132 and theupper surface 152 of theinferior plate 134. Eachspring arm detent 222 extends partially into the endplate and provides a small cavity designed to receive the lip of a spring arm on a disc insertion tool. As explained in further detail below, the interaction between thedetent 222 and the spring arm of the disc insertion tool provides additional stability for the intervertebral disc prosthesis during the implantation process. - Shear-Limiting Features
- With reference to
FIGS. 8 and 9 , theintervertebral disc prosthesis 130 is configured to allow theendplates FIG. 8 shows a cross-sectional view of theprosthesis 130 with theendplates FIG. 9 shows a cross-sectional view of theprosthesis 130 with theendplates posterior side 182. As shown in bothFIG. 8 andFIG. 9 , the degree to which the endplates are allowed to pivot is restricted by theradial flange 160 of thecore 136. In particular, when anendplate core 136, thecollar flange 160 of the core and thus prohibit further pivoting of theendplate core 136. - In an alternative embodiment, the
radial flange 160 of the core may be extended toward the inferior endplate or the superior endplate to further limit or prevent articulation on that side of the core. For example, with reference toFIG. 14A , thecore 136 comprises a central disc portion 138 and aradial flange portion 160. The central disc portion includes anupper bearing surface 162 and alower bearing surface 164. The convexupper bearing surface 162 engages the concave articulating surface 143 of thesuperior plate 132, while the convexlower bearing surface 164 engage the concave articulating surface 145 of theinferior plate 134. Theflange portion 160 is positioned in a ring-like fashion about the central disc portion 138. - The
flange portion 160 includes a radially extending portion 166 and a lip portion 168. The radially extending portion 166 extends outwardly from the central disc portion 138 in a radial direction (relative to a vertical axis of the prosthesis). The lip portion 168 extends in an axial direction relative to the radially extending portion 166 and forms a ring about the central disc portion 138. As explained in further detail below with reference toFIGS. 15-17 , thecore 136 may be formed as an integral component or a combination of materials and components. - In the embodiment of
FIG. 14A , the lip portion 168 of theflange 160 extends downward and encompasses thecollar 158 of theinferior plate 134 in the neutral position (i.e., with the endplate un-pivoted relative to the core in the lateral bending plane or flexion plane). However, in this embodiment, the lip portion 168 of theflange 160 does not contact the surface of theendplate 134 around thecollar 158 in the neutral position. This configuration substantially limits the amount of pivoting allowed for the inferior endplate relative to the core. At the same time, the lip portion 168 of the flange extends only slightly upward and does not encompass thecollar 148 of thesuperior plate 132 in the neutral position. This allows normal pivoting of thesuperior endplate 132 relative to thecore 136. - In another embodiment, such as that shown in
FIG. 14B , the lip portion 168 of theflange 160 of thecore 136 is configured to extend completely to theinferior endplate 134 when the inferior endplate is in the neutral position. Furthermore, the lip portion 168 of theflange 160 encases thecollar 158 of the inferior endplate when the endplate is in a neutral position. In this embodiment, the lip portion 166 on theflange 160 of the core 136 substantially conforms to and engages an upper surface of theinferior endplate 134, including thecollar 158. In an alternative embodiment, the lip portion 168 of theflange 160 of thecore 136 is also configured to engage thegroove 210 in thecollar 158. Such engagement between the lip portion 168 of thecore 136 and thegroove 210 of theendplate 134 may be provided in a snap fit engagement to secure thecore 136 to theendplate 134. When securing the core to the inferior endplate, the core may be stretched and pressed to properly engage the lip portion 168 of theflange 160 with the upper surface of theinferior endplate 134, thus properly positioning thecore 136 on theinferior endplate 134. After positioning thecore 136 on theinferior endplate 134, theextended flange 160 of the core, and particularly the lip portion 168 of theflange 160, prevents theinferior endplate 134 from lateral bending and flexion relative to thecore 136. - In addition to the above, it will be recognized from
FIG. 14B that the fit between theflange 160 and thecollar 158 of theinferior endplate 134 may also prohibit or significantly restrict torsional movement of the inferior endplate relative to the core. In particular, if a relatively tight fit is provided between theflange 160 and thecollar 158, torsional movement will be prevented or restricted. However, if a relatively loose fit is provided between theflange 160 and thecollar 158, torsional movement may be allowed. - In yet another embodiment, the
flange 160 extends to the surface of the inferior endplate and includes protrusions that are press-fit into holes or other indentations formed in the surface of theinferior endplate 134. In this embodiment, thecore 136 is fixed to the inferior plate by the protrusions that fit into the holes, intentionally preventing movement of theendplate 134 relative to thecore 136. These protrusions on the core may be press-fit into the holes in the inferior plate when the physician assembles the prosthesis. - Each of the above embodiments are designed to limit the amount of articulation between the
endplates core 136 and thus provide shear resistance to help protect the facets. Although the features have been shown with respect to theinferior endplate 134, they could likewise be provided with respect to thesuperior endplate 132. - Alternative Materials
- As discussed above, the
metal endplates core 136 may be comprised of a plastic material such as ultra high molecular weight polyethylene. Because plastic materials are typically not radio-opaque, a cobalt chromium alloy wire may be provided around the core to allow the physician to determine the location of the core when viewing an x-ray image of an installed prosthesis. The cobalt chromium alloy wire is typically inserted into a channel on the core, such aschannel 37 ofFIG. 1 andchannel 137 ofFIG. 4 . - In many cases, a physician may desire an MRI image rather than an x-ray image of an implanted prosthesis. Unfortunately, cobalt chromium alloy is not MRI compatible. Thus, in an alternative embodiment of the prosthesis, the
endplates core channel 137, are all comprised of titanium. The use of titanium allows the endplates and core wire of an implanted prosthesis to be MRI compatible. Other MRI compatible materials that could be used for the endplates and core wire include ceramics, polycarbonate-polyurethane (PCPU), polyetheretherketone (PEEK), or composites thereof. - In addition to alternative materials that make the intervertebral prosthesis MRI compatible, other materials may be advantageous to the surgeon, depending upon the desired outcome for the patient. For example, a ceramic core could be used for excellent wear performance in the youngest patients. A PCPU core could be used to offer shock-absorbing capabilities for more active patients.
- Composite Core
- In one embodiment, the
core 136 is a composite core comprised of a plurality of different portions made of different materials exhibiting different properties. For example,FIGS. 15-17 show a plurality of different embodiments for a composite core comprising at least two materials with different properties, joined to form a single component. One embodiment of the composite core is a dual durometer core having a relatively soft bearing surface and a hardened flange. - With reference to
FIGS. 15 and 15 A, thecore 136 is formed as a three-part composite core comprising acentral disc portion 163, anupper bearing portion 162, and alower bearing portion 164. Theradial flange 160 is provided by thedisc portion 163 and encompasses aconvex bearing surface 161. The bearingsurface 161 is provided by theupper bearing portion 162 and thelower bearing portion 164. The surface of theupper bearing portion 162 is designed to engage thesocket 149 of thesuperior endplate 132 and the surface of thelower bearing portion 164 is designed to engage the socket of theinferior endplate 134. Theupper bearing portion 162 andlower bearing portion 164 are fixed to thedisc portion 163 such that the core is provided as a unitary piece. Thecore 136 may be configured such that the bearingportions disc portion 163 by any number of different methods, such as press-fit, threaded engagement, snap fit, welding, insert or two-shot injection molding, insert compression molding, brazing, bonding with adhesives, sintering, or other methods as will be recognized by those of skill in the art. - Another embodiment of a composite core is shown in
FIGS. 16 and 16 A. In this embodiment, thecore 136 is a two-part composite core comprising acentral bearing portion 262 and anouter ring portion 264 encircling the central bearing portion. Thetop surface 261 of thecentral bearing portion 262 is designed to engage the socket of thesuperior plate 132, and thebottom surface 263 of thecentral bearing portion 262 is designed to engage the socket of theinferior plate 134. Theouter ring portion 264 is theflange 160 of thecore 136. When thecentral bearing portion 262 is comprised of a relatively soft material and theouter ring portion 263 is comprised of a relatively hard material, thering portion 263 acts as a retaining wall for the bearingportion 262, making the bearing portion creep resistant. In particular, when the soft material of the bearingportion 262 is compressed following implantation in the patient, the harder material of thering portion 263 prevents the soft material of the bearing portion from deforming into a flatter shape. Alternatively, the bearingportion 262 may be comprised of a relatively hard wear-resistant material while thering portion 263 may be comprised of a relatively resilient or tough material that limits extreme motions, such as that shown inFIGS. 14 and 14 A. Thecore 136 may be configured such that the bearingportion 262 is attached to thering portion 163 by any number of different methods, such as press-fit, snap fit, welding, insert or two-shot injection molding, insert compression molding, brazing, bonding with adhesives, sintering, or other methods as will be recognized by those of skill in the art. -
FIGS. 17, 17A and 17B show yet another embodiment of theprosthesis core 136. In this embodiment, theprosthesis core 136 is specifically designed to allow injection molding of two materials using insert or two-shot molding, where a second material is molded over a first material. As shown inFIG. 17A , the core comprises aninner skeleton 266 of a first material and anouter bearing flesh 267 of a second material. Theskeleton 266 is generally disc shaped and the material of the skeleton extends continuously across the core from one point on theflange 160 to an opposite point on the flange. The skeleton also provides aridge 269 where the bearingflesh 267 abuts theskeleton 266. However, in certain locations on thecore 136, as shown inFIG. 17B , the skeleton does not extend continuously across the core, and is interrupted by portions of bearingflesh 267. This arrangement provides a cohesive part with strong mechanical interconnections. Furthermore, if the bearingflesh 267 is comprised of a relatively soft material and theskeleton 266 is comprised of a relatively hard material, the flange of the skeleton provides a retaining wall along with theridge 269 to prevent creep of the soft bearing material during compression. As discussed above, the arrangement shown inFIGS. 17-17B is specifically configured for insert molding of the core. - From the above examples it will be clear that a
core 136 may be provided in multiple portions comprised of differing materials such that the properties of the core vary from location to location in an advantageous manner. For example, as discussed above, the core may be manufactured in a manner such that the core provides a soft bearing surface on the exterior and a rigid support skeleton on the inside. As another example, the core may be manufactured with a hard bearing surface and a relatively resilient skeleton. - Example materials for use with the core include PEEK or titanium with a wear-improving coating, PCPU, MMC, cobalt chromium alloy, ceramics, double- network hydrogels, in addition to ultra-high molecular weight polyethylene (UHMWPE). Alternate combinations of interest from a wear perspective include metal matrix composites (MMC) with cobalt chromium or MMC with ceramic. Example ceramics include synthetic ruby, zirconia, alumina, zirconia toughened alumina (ZTA), Y-TZP, silicon nitride, or combinations thereof.
- Examples of core material combinations and arrangements include a ruby bearing portion brazed to a metal flange; a cobalt chromium, titanium or stainless steel flange press fit around a ceramic bearing; a MMC such as titanium with titanium carbide bearing surface over a titanium skeleton; polycarbonate-polyurethane (PCPU) or UHMWPE bearing surfaces injection or compression molded over a metal flange insert; a ceramic bearing with a PCPU or UHMWPE flange; or a PEEK bearing with PCPU or a metal flange skeleton. As another example, a PCPU core could be produced by multi-shot or insert injection molding a relatively rigid central frame and flange with a relatively soft outer bearing surface (e.g., shore 55D frame and shore 80A bearing). In another example embodiment, layered sintering of MMC to a similar metal results in a MMC bearing surface applied to a metal frame, thus providing a bearing surface with ceramic-like properties and a retention flange with non-ceramic (i.e., non-brittle) properties.
- Modular Prosthesis Components
- As described above, various configurations and compositions are possible for the
endplates core 136. With a wide variety of differing endplates and cores available, the surgeon may desire a specific endplate and core combination based on the particular needs of a patient. Therefore, the various endplates and cores are made available to the surgeon as part of a modular prosthesis system, where differing endplates may be matched with any number of different cores to arrive at the desired prosthesis. This provides the surgeon with a method of designing an intervertebral disc prosthesis that is customized to the needs of the particular patient. - When customizing the intervertebral prosthesis, the surgeon analyzes and/or tests the patient to determine features that may be desirable for the patient based on his or her particular situation. These features may include, for example, material composition of the prosthesis, structural features, and size of the prosthesis. The surgeon then decides which features to include in the patient's intervertebral prosthesis, and places an order for the desired prosthesis with the prosthesis manufacturer. The surgeon's decision to order certain structural features, sizes, or materials for the prosthesis will likely be made based on the patient's concerns, the patient's medical history, testing conducted on the patient, the patient's age, the patient's size, the patient's health, the patient's activity level, and the physician's general best judgment. The surgeon's order includes a description of the desired endplates as well as a description of the desired core. After the customized prosthesis is ordered, a manufacturer or other assembler puts together a prosthesis package for the physician and patient by selecting the modular endplate and core components that provide the desired prosthetic device. The components are then delivered to the physician for implantation in the patient.
- As an example of the modular prosthesis system in operation, consider a particular situation where the patient is allergic to nickel. In this situation, the surgeon will not want to use a cobalt chromium endplate, since nickel is found in cobalt chromium alloy, and the patient's body is likely to have an adverse reaction to the nickel. However, because the prosthesis described herein may be assembled from various modular components, the surgeon will have the choice of selecting an endplate that contains no nickel, such as a titanium endplate. In addition, the surgeon may determine that a patient may benefit from a core having a rigid ceramic-like bearing surface with a non-brittle and more cushioned retention flange. For this core, the surgeon may use a core comprised of an MMC material applied to a metal frame using layered sintering. As another example, the surgeon may decide that movement of the inferior endplate should be restricted for a particular patient. In this case, the surgeon may order a prosthesis having a core similar to that of
FIG. 14B as opposed to the core shown inFIGS. 8 and 9 . In any case, the modular characteristics of the prosthesis system described herein allow the surgeon to choose endplates and a core that together provide the prosthesis that is most appropriate for the patient. - After receiving an order for an intervertebral disc prosthesis having a specified superior plate, core, and inferior plate, the seller of the prosthetic devices obtains the appropriate modular components and sends them to the physician. After receiving the modular components, the physician assembles the components before implanting the assembled prosthesis in the patient.
- It should be recognized that various alternative methods of ordering and order fulfillment of customized prosthetic devices are available. Orders for customized prosthetic devices may be placed by mail, telephone, on-line or by any other method known in the art. In addition, the orders may be received, assembled and shipped by a single entity or by different entities cooperating with each other. Furthermore, the entity receiving and/or fulfilling the order may be completely independent of the surgeon or associated with the surgeon in some way. For example, a hospital may purchase an array of modular components from a manufacturer and make custom prosthetic devices available to surgeons associated with the hospital. In this situation a surgeon would place an order for the custom prosthetic device directly with the hospital. After receiving the request for the custom prosthetic device, the hospital would assemble the requested prosthetic device and deliver it to the surgeon.
- Insertion of Intervertebral Prosthesis
- After selecting and receiving the
proper endplates core 136 for a particular patient, the surgeon assembles theintervertebral prosthesis 130 by sandwiching the core between the endplates. Once assembled the prosthesis may be implanted in the patient as a complete unit using an insertion/distraction instrument. - In particular, with reference to
FIG. 18 anintervertebral prosthesis 130 is shown positioned within adisc insertion tool 300. Thedisc insertion tool 300 generally includes ahandle 302 and associatedlever 304.Separate insertion arms 306 extend from the handle. Theinsertion arms 306 end inflat fingers 308 that contact one another at atip 310 opposite thehandle 302. Holding prongs/retention arms 312 are provided between the insertion arms. Theretention arms 312 are designed to retain theprosthesis 130 on thedisc insertion tool 300 by engaging the insertion features, such asindentations endplates lever 304 causes a ratcheting operation that moves theinsertion arms 312 andprosthesis 300 toward thetip 310. - As shown in
FIG. 19 , once the old disc is removed from the intervertebral space, thetip 310 of the disc insertion tool is placed in the intervertebral space with blunt edges of theinsertion arms 306 positioned against thevertebral bodies 320. As the prosthesis is gradually ratcheted toward the intervertebral space thecentral channel 202 of theprosthesis 130 receives the insertion arms/distracting ramp 306, and this engagement properly orients and stabilizes theprosthesis 130 as it enters the vertebral space. Furthermore, as the prosthesis is ratcheted further and further down theinsertion arms 306 toward thetip 310, the prosthesis causes theinsertion arms 306 to spread apart near thetip 310. As theinsertion arms 306 andfingers 308 are moved apart, space is created between thevertebral bodies 320 for theprosthesis 130. - The height of the
fingers 308 in the intervertebral space is greater than the height of theteeth 146 on theprosthesis 130. This allows theprosthesis 130 to slide into position between thevertebral bodies 320, moving along theinsertion arms 306 andfingers 308 without contacting thevertebral bodies 320 until thefingers 308 are removed from the intervertebral space. - Stop blocks 314 are provided on the disc insertion tool toward the rear of the
retention arms 312. In one embodiment, the position of the stop blocks 314 could be adjustable relative to theinsertion arms 312. The stop blocks 314 are designed to prevent theprosthesis 130 from being inserted too far into the intervertebral space. In particular, when theprosthesis 130 has been moved down the insertion arms and to a position in the intervertebral space such that the disc insertion tool should be removed, the stop blocks 314 will contact thevertebral bodies 320 at the end of theinsertion arms 306.FIG. 20 shows thedisc insertion tool 300 near such a position. Continued ratcheting of thelever 304 at this point causes theinsertion arms 306 to retract from thevertebral bodies 320, as the stop blocks 314 press against the vertebral bodies. Once theinsertion fingers 308 are removed from the intervertebral space, theteeth 146 of theprosthesis 130 contact thevertebral bodies 320. Natural compression of theprosthesis 130 by thevertebral bodies 320 causes theteeth 146 to sink into the vertebral bodies, securing theprosthesis 130 in place between the vertebral bodies. Bony in-growth between the endplate and bone further secures the prosthesis in place over time. - An alternative embodiment of
disc insertion tool 300 is shown inFIGS. 21 and 22 . This embodiment of thedisc insertion tool 300 is configured for use with the intervertebral disc prosthesis shown inFIG. 12A . In this embodiment, thedisc insertion tool 300 includes anti-rotation pegs 318 as well asspring arms 316. The anti-rotation pegs 318 are fixed to theretention arms 312 of thedisc insertion tool 300. Oneanti-rotation peg 318 is provided on atop retention arm 312 a and another anti-rotation peg is provided on alower retention arm 312 b (the lower anti-rotation peg is not shown in the figures). When the anti-rotation pegs 318 are fully inserted into theanti-rotation notches 218 of thedisc prosthesis 130, as shown inFIG. 21 , theprosthesis 130 is prevented from rotating relative to the disc insertion tool, thus maintaining the proper orientation of the disc prosthesis during the implantation procedure. - The
spring arms 316 are provided at the central back portion of theretention arms 312. Thespring arms 316 are cantilever arms having resilient qualities that allow the spring arms to bend and spring back into place. Thespring arms 316 each include a lip extending from the end of the spring arm. These lips are designed to fit into thespring arm detents 222 of the disc prosthesis 130 (seeFIG. 12A ). When the lips of thespring arms 316 extend into thespring arm detents 222, thedisc prosthesis 130 is further secured to theinsertion tool 300 during the implantation process. Once thedisc prosthesis 130 is properly situated in the intervertebral space, thespring arms 316 may be automatically released, allowing the lips of the spring arms to move away from thespring arm detents 222. With thespring arms 316 released, thedisc insertion tool 300 may be pulled away, leaving thedisc prosthesis 130 in place in the intervertebral space. - Alternative Embodiments Possible
- Although the present invention has been described with respect to certain preferred embodiments, it will be appreciated by those of skill in the art that other implementations and adaptations are possible. For example, the prosthetic disc components shown in the attached drawings are most commonly associated with artificial lumbar discs, but the features described herein could also apply to other discs such as artificial cervical discs.
- Another example of a possible alternative embodiment is shown in
FIG. 9A . In this embodiment, theprosthesis 130 comprises asuperior endplate 132,inferior endplate 134 and anintermediate core 136. However, unlike the embodiment ofFIG. 9 which included a socket and concave bearing surface on each endplate, the embodiment ofFIG. 9A includes opposing concave bearing surfaces 151 and 153 on theintermediate core 136. These concave bearing surfaces 151 and 153 respectively engage convex bearing surface 165 of thesuperior plate 132 and convex bearing surface 167 of the inferior plate 167. In this embodiment, thecore 136 essentially provides opposing sockets for the substantially spherical/ball-shaped bearing surfaces of theendplates endplates core 136, as the bearing surfaces 165 and 167 of the endplates engage the bearing surfaces 151 and 153 of the core. - In addition to the above, it should be recognized that there are advantages to individual advancements described herein that may be obtained without incorporating other aspects described above. In view of the foregoing, the spirit and scope of the appended claims should not be limited to the description of the preferred embodiments contained herein.
Claims (24)
1. An intervertebral disc prosthesis comprising:
a) a first endplate including a first vertebra fixation surface;
b) a second endplate including a second vertebra fixation surface, wherein the first endplate is operable to pivot relative to the second endplate; and
c) a composite material provided on the first vertebra fixation surface, the composite material comprising an osteoconductive material and an osteoinductive material.
2. The intervertebral disc prosthesis of claim 1 wherein the osteoconductive material is permeated with the osteoinductive material.
3. The intervertebral disc prosthesis of claim 1 wherein the composite material includes a resorbable portion doped with the osteoinductive material and a non-resorbable portion comprising the osteoconductive material.
4. The intervertebral disc prosthesis of claim 3 wherein the resorbable portion comprises a resorbable carrier selected from the group consisting of calcium phosphate, hydroxyapatite, collagen, biodegradable polyglycolic acid, polylactic acid or a hydrogel.
5. The intervertebral disc prosthesis of claim 1 wherein the osteoconductive material is selected from the group consisting of titanium, metal matrix composite, ceramic, calcium phosphate, hydroxyapatite or a matrix of cross-linked collagen fibers coated with hydroxyapatite.
6. The intervertebral disc prosthesis of claim 1 wherein the osteoinductive material is selected from the group consisting of bone morphogenetic protein, bone marrow or stem cells.
7. A method of fixing an intervertebral disc prosthesis in an intervertebral space, the method comprising:
a) providing an intervertebral disc prosthesis including at least one vertebra fixation surface; and
b) applying a composite material to the vertebra fixation surface, the composite material comprising an osteoconductive component and an osteoinductive component.
8. The method of claim 7 further comprising the step of inserting the intervertebral disc prosthesis in an intervertebral space with the vertebra fixation surface in contact with a vertebral body.
9. The method of claim 7 wherein the at least one vertebra fixation surface includes a first vertebra fixation surface and a second vertebra fixation surface, wherein the first vertebra fixation surface is operable to pivot relative to the second vertebra fixation surface.
10. The method of claim 7 wherein the osteoconductive component comprises a first material and the osteoinductive component comprises a second material, and wherein the first material is permeated with the second material.
11. The method of claim 10 further comprising the step of soaking the first material in the second material in order to permeate the first material with the second material.
12. The method of claim 7 wherein the vertebra fixation surface comprises a textured surface.
13. The method of claim 12 wherein the step of applying the composite material to the vertebra fixation surface comprises the step of packing the composite material on the textured surface.
14. The intervertebral disc prosthesis of claim 7 wherein the osteoinductive component includes a resorbable portion and the osteoconductive component includes a non-resorbable portion.
15. The intervertebral disc prosthesis of claim 14 wherein the resorbable portion is doped with an osteoinductive material, and the osteoinductive material includes bone morphogenetic protein or bone marrow.
16. An intervertebral disc prosthesis comprising:
a) a first vertebra fixation surface; and
b) a composite material provided on the first vertebra fixation surface, the composite material comprising an osteoconductive material and an osteoinductive material.
17. The intervertebral disc prosthesis of claim 16 further comprising a second vertebra fixation surface, wherein the first vertebra fixation surface is operable to pivot relative to the second vertebra fixation surface.
18. The intervertebral disc prosthesis of claim 17 further comprising a bearing surface positioned between the first vertebra fixation surface and the second vertebra fixation surface, wherein the first vertebra fixation surface is operable to pivot upon the bearing surface.
19. The intervertebral disc prosthesis of claim 16 wherein the osteoconductive material is permeated with the osteoinductive material.
20. The intervertebral disc prosthesis of claim 19 wherein the first vertebra fixation surface comprises a textured surface, and the composite material is applied to the textured surface.
21. The intervertebral disc prosthesis of claim 16 wherein the composite material includes a resorbable portion and a non-resorbable portion.
22. The intervertebral disc prosthesis of claim 21 wherein the resorbable portion is doped with the osteoinductive material and the non-resorbable portion comprises the osteoconductive material.
23. The intervertebral disc prosthesis of claim 16 further comprising an endplate including a face, wherein the first vertebra fixation surface is provided on the face of the endplate.
24. The intervertebral disc prosthesis of claim 23 wherein at least one tooth is included on the face of the endplate and the first vertebra fixation surface is provided on the at least one tooth.
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PCT/US2007/008248 WO2007117425A2 (en) | 2005-10-31 | 2007-03-30 | Spinal prosthesis comprising composite materials and method of use |
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Cited By (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20070073404A1 (en) * | 2005-09-23 | 2007-03-29 | Ralph Rashbaum | Intervertebral disc prosthesis |
US20070100453A1 (en) * | 2005-10-31 | 2007-05-03 | Depuy Spine, Inc. | Intervertebral disc prosthesis |
US20080103598A1 (en) * | 2006-09-15 | 2008-05-01 | Trudeau Jeffrey L | System and Method for Sizing, Inserting and Securing Artificial Disc in Intervertebral Space |
US20090240333A1 (en) * | 2007-09-17 | 2009-09-24 | Trudeau Jeffrey L | Motion Preserving Artificial Intervertebral Disc Device |
US20100016974A1 (en) * | 2006-09-15 | 2010-01-21 | Janowski Brian P | Systems and methods for securing an implant in intervertebral space |
US7695516B2 (en) | 2004-12-22 | 2010-04-13 | Ldr Medical | Intervertebral disc prosthesis |
US20100241231A1 (en) * | 2009-02-20 | 2010-09-23 | Marino James F | Intervertebral fixation device |
US20100262244A1 (en) * | 2009-04-14 | 2010-10-14 | Warsaw Orthopedic, Inc. | Metal Coated Implant |
US20100280619A1 (en) * | 2006-09-15 | 2010-11-04 | Hansen Yuan | Systems and methods for sizing, inserting and securing an implant in intervertebral space |
US20110035006A1 (en) * | 2009-08-07 | 2011-02-10 | Ebi, Llc | Toroid-Shaped Spinal Disc |
US8002835B2 (en) | 2004-04-28 | 2011-08-23 | Ldr Medical | Intervertebral disc prosthesis |
US20110251690A1 (en) * | 2010-04-09 | 2011-10-13 | Roger Berger | Intervertebral implant |
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US20220062002A1 (en) * | 2004-05-13 | 2022-03-03 | Moskowitz Family Llc | Artificial cervical and lumbar disc system |
US11957598B2 (en) | 2004-02-04 | 2024-04-16 | Ldr Medical | Intervertebral disc prosthesis |
Families Citing this family (84)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
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EP2329778A3 (en) | 2003-01-31 | 2012-06-20 | Spinalmotion, Inc. | Spinal midline indicator |
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US10052211B2 (en) | 2003-05-27 | 2018-08-21 | Simplify Medical Pty Ltd. | Prosthetic disc for intervertebral insertion |
US7575599B2 (en) | 2004-07-30 | 2009-08-18 | Spinalmotion, Inc. | Intervertebral prosthetic disc with metallic core |
US7585326B2 (en) | 2004-08-06 | 2009-09-08 | Spinalmotion, Inc. | Methods and apparatus for intervertebral disc prosthesis insertion |
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WO2006104722A2 (en) * | 2005-03-24 | 2006-10-05 | Accelerated Innovation, Llc | Intervertebral disc replacement device |
US20070173941A1 (en) * | 2006-01-25 | 2007-07-26 | Sdgi Holdings, Inc. | Intervertebral prosthetic disc and method of installing same |
US20070208426A1 (en) * | 2006-03-03 | 2007-09-06 | Sdgi Holdings, Inc. | Spinal implant with improved surface properties for delivery |
JP2009533187A (en) | 2006-04-12 | 2009-09-17 | スパイナルモーション, インコーポレイテッド | Posterior spine apparatus and method |
US8043379B2 (en) * | 2006-04-21 | 2011-10-25 | Depuy Spine, Inc. | Disc prosthesis having remote flexion/extension center of rotation |
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US9381098B2 (en) * | 2006-09-28 | 2016-07-05 | Spinal Kinetics, Inc. | Tool systems for implanting prosthetic intervertebral discs |
US7905919B2 (en) | 2006-11-07 | 2011-03-15 | Biomedflex Llc | Prosthetic joint |
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US20110166671A1 (en) | 2006-11-07 | 2011-07-07 | Kellar Franz W | Prosthetic joint |
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US8105382B2 (en) | 2006-12-07 | 2012-01-31 | Interventional Spine, Inc. | Intervertebral implant |
CA2675222A1 (en) * | 2007-01-12 | 2008-07-24 | Synthes Usa, Llc | Modular intervertebral implant |
US7942104B2 (en) | 2007-01-22 | 2011-05-17 | Nuvasive, Inc. | 3-dimensional embroidery structures via tension shaping |
US7946236B2 (en) | 2007-01-31 | 2011-05-24 | Nuvasive, Inc. | Using zigzags to create three-dimensional embroidered structures |
US8900307B2 (en) | 2007-06-26 | 2014-12-02 | DePuy Synthes Products, LLC | Highly lordosed fusion cage |
WO2009006455A1 (en) * | 2007-06-29 | 2009-01-08 | Nuvasive, Inc. | Facet joint implant and related methods |
US8486081B2 (en) * | 2007-07-23 | 2013-07-16 | DePuy Synthes Products, LLC | Implant insertion device and method |
US20090043391A1 (en) | 2007-08-09 | 2009-02-12 | Spinalmotion, Inc. | Customized Intervertebral Prosthetic Disc with Shock Absorption |
US8282681B2 (en) | 2007-08-13 | 2012-10-09 | Nuvasive, Inc. | Bioresorbable spinal implant and related methods |
US8801758B2 (en) | 2007-08-13 | 2014-08-12 | Stryker Spine | Insertion instrument for intervertebral implants |
WO2009055481A1 (en) | 2007-10-22 | 2009-04-30 | Spinalmotion, Inc. | Dynamic spacer device and method for spanning a space formed upon removal of an intervertebral disc |
EP2211785B1 (en) * | 2007-10-25 | 2016-01-27 | Synergy Disc Replacement, Inc. | Systems for vertebral disc replacement |
US8142441B2 (en) * | 2008-10-16 | 2012-03-27 | Aesculap Implant Systems, Llc | Surgical instrument and method of use for inserting an implant between two bones |
US8591587B2 (en) | 2007-10-30 | 2013-11-26 | Aesculap Implant Systems, Llc | Vertebral body replacement device and method for use to maintain a space between two vertebral bodies within a spine |
EP2471493A1 (en) | 2008-01-17 | 2012-07-04 | Synthes GmbH | An expandable intervertebral implant and associated method of manufacturing the same |
EP2244671A4 (en) * | 2008-01-25 | 2013-03-20 | Spinalmotion Inc | Intervertebral prosthetic disc with shock absorbing core formed with disc springs |
US8764833B2 (en) | 2008-03-11 | 2014-07-01 | Spinalmotion, Inc. | Artificial intervertebral disc with lower height |
US8377135B1 (en) | 2008-03-31 | 2013-02-19 | Nuvasive, Inc. | Textile-based surgical implant and related methods |
BRPI0910325A8 (en) | 2008-04-05 | 2019-01-29 | Synthes Gmbh | expandable intervertebral implant |
US9034038B2 (en) | 2008-04-11 | 2015-05-19 | Spinalmotion, Inc. | Motion limiting insert for an artificial intervertebral disc |
KR20110009216A (en) | 2008-05-05 | 2011-01-27 | 스피날모우션, 인코포레이티드 | Polyaryletherketone artificial intervertebral disc |
US9220603B2 (en) | 2008-07-02 | 2015-12-29 | Simplify Medical, Inc. | Limited motion prosthetic intervertebral disc |
WO2010000766A2 (en) * | 2008-07-03 | 2010-01-07 | Ceramtec Ag | Intervertebral disc endoprosthesis |
EP2299944A4 (en) | 2008-07-17 | 2013-07-31 | Spinalmotion Inc | Artificial intervertebral disc placement system |
WO2010009153A1 (en) | 2008-07-18 | 2010-01-21 | Spinalmotion, Inc. | Posterior prosthetic intervertebral disc |
US9526620B2 (en) * | 2009-03-30 | 2016-12-27 | DePuy Synthes Products, Inc. | Zero profile spinal fusion cage |
US8377136B2 (en) * | 2009-04-20 | 2013-02-19 | Warsaw Orthopedic, Inc. | Method for stabilizing an intervertebral disc device |
US8394125B2 (en) | 2009-07-24 | 2013-03-12 | Zyga Technology, Inc. | Systems and methods for facet joint treatment |
US20110035010A1 (en) * | 2009-08-07 | 2011-02-10 | Ebi, Llc | Toroid-shaped spinal disc |
US8979860B2 (en) | 2010-06-24 | 2015-03-17 | DePuy Synthes Products. LLC | Enhanced cage insertion device |
US9282979B2 (en) | 2010-06-24 | 2016-03-15 | DePuy Synthes Products, Inc. | Instruments and methods for non-parallel disc space preparation |
EP2588034B1 (en) | 2010-06-29 | 2018-01-03 | Synthes GmbH | Distractible intervertebral implant |
US20120078373A1 (en) | 2010-09-23 | 2012-03-29 | Thomas Gamache | Stand alone intervertebral fusion device |
US8353964B2 (en) | 2010-11-04 | 2013-01-15 | Carpenter Clyde T | Anatomic total disc replacement |
US8496713B2 (en) | 2010-12-10 | 2013-07-30 | Globus Medical, Inc. | Spine stabilization device and methods |
US8998991B2 (en) * | 2011-02-23 | 2015-04-07 | Globus Medical, Inc. | Six degree spine stabilization devices and methods |
RU2465870C1 (en) * | 2011-02-28 | 2012-11-10 | Общество с ограниченной ответственностью "Эндокарбон" | Intervertebral disc prosthesis |
US8500749B2 (en) * | 2011-04-19 | 2013-08-06 | Prescient Surgical Designs, Llc | Apparatus and method for inserting intervertebral implants |
US9017410B2 (en) | 2011-10-26 | 2015-04-28 | Globus Medical, Inc. | Artificial discs |
US9271836B2 (en) | 2012-03-06 | 2016-03-01 | DePuy Synthes Products, Inc. | Nubbed plate |
CN103417313B (en) * | 2012-05-18 | 2016-07-06 | 朱悦 | A kind of artificial neck lumbar intervertebral disc |
US9204972B2 (en) | 2013-03-01 | 2015-12-08 | Globus Medical, Inc. | Articulating expandable intervertebral implant |
US9770343B2 (en) | 2013-03-01 | 2017-09-26 | Globus Medical Inc. | Articulating expandable intervertebral implant |
US9198772B2 (en) | 2013-03-01 | 2015-12-01 | Globus Medical, Inc. | Articulating expandable intervertebral implant |
US10004607B2 (en) | 2013-03-01 | 2018-06-26 | Globus Medical, Inc. | Articulating expandable intervertebral implant |
US9522070B2 (en) | 2013-03-07 | 2016-12-20 | Interventional Spine, Inc. | Intervertebral implant |
CA2906846C (en) * | 2013-03-15 | 2021-10-26 | Lifenet Health | Medical implant for fixation and integration with hard tissue |
US9198770B2 (en) | 2013-07-31 | 2015-12-01 | Globus Medical, Inc. | Artificial disc devices and related methods of use |
US20160034775A1 (en) | 2014-08-02 | 2016-02-04 | General Vault, LLC | Methods and apparatus for bounded image data analysis and notification mechanism |
US10105240B2 (en) * | 2014-08-19 | 2018-10-23 | Oxford Performance Materials, Inc. | Spinal implant and method for fabricating the same |
JP6971979B2 (en) * | 2015-10-16 | 2021-11-24 | グローバス メディカル インコーポレイティッド | Articulated expandable facet implant |
CN105853031B (en) * | 2016-04-29 | 2017-10-03 | 西安交通大学第二附属医院 | A kind of bionical anti-artificial lumbar vertebrae of dislocation and interverbebral disc junctional complex |
US10426628B2 (en) | 2017-12-14 | 2019-10-01 | Simplify Medical Pty Ltd | Intervertebral prosthesis |
US11197765B2 (en) | 2019-12-04 | 2021-12-14 | Robert S. Bray, Jr. | Artificial disc replacement device |
US11903841B2 (en) | 2020-06-22 | 2024-02-20 | Warsaw Orthopedic, Inc. | In-situ additive channeled implants |
US11903846B2 (en) | 2019-12-17 | 2024-02-20 | Warsaw Orthopedic, Inc. | In-situ additive expandable implants |
US11839554B2 (en) | 2020-01-23 | 2023-12-12 | Robert S. Bray, Jr. | Method of implanting an artificial disc replacement device |
US11426286B2 (en) | 2020-03-06 | 2022-08-30 | Eit Emerging Implant Technologies Gmbh | Expandable intervertebral implant |
US20220111116A1 (en) * | 2020-10-14 | 2022-04-14 | Warsaw Orthopedic, Inc. | Additive-manufactured non-woven fibrous implants, systems, and related methods |
US11850160B2 (en) | 2021-03-26 | 2023-12-26 | Medos International Sarl | Expandable lordotic intervertebral fusion cage |
US11752009B2 (en) | 2021-04-06 | 2023-09-12 | Medos International Sarl | Expandable intervertebral fusion cage |
Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6039763A (en) * | 1998-10-27 | 2000-03-21 | Disc Replacement Technologies, Inc. | Articulating spinal disc prosthesis |
US6368350B1 (en) * | 1999-03-11 | 2002-04-09 | Sulzer Spine-Tech Inc. | Intervertebral disc prosthesis and method |
US6520996B1 (en) * | 1999-06-04 | 2003-02-18 | Depuy Acromed, Incorporated | Orthopedic implant |
US6758862B2 (en) * | 2002-03-21 | 2004-07-06 | Sdgi Holdings, Inc. | Vertebral body and disc space replacement devices |
US6790233B2 (en) * | 2001-05-01 | 2004-09-14 | Amedica Corporation | Radiolucent spinal fusion cage |
US20050165485A1 (en) * | 2004-01-27 | 2005-07-28 | Sdgi Holdings, Inc. | Hybrid intervertebral disc system |
Family Cites Families (65)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0176728B1 (en) | 1984-09-04 | 1989-07-26 | Humboldt-Universität zu Berlin | Intervertebral-disc prosthesis |
DE3809793A1 (en) | 1988-03-23 | 1989-10-05 | Link Waldemar Gmbh Co | SURGICAL INSTRUMENT SET |
FR2659226B1 (en) | 1990-03-07 | 1992-05-29 | Jbs Sa | PROSTHESIS FOR INTERVERTEBRAL DISCS AND ITS IMPLEMENTATION INSTRUMENTS. |
GB9125798D0 (en) | 1991-12-04 | 1992-02-05 | Customflex Limited | Improvements in or relating to spinal vertebrae implants |
US5258031A (en) | 1992-01-06 | 1993-11-02 | Danek Medical | Intervertebral disk arthroplasty |
DE4208116C2 (en) | 1992-03-13 | 1995-08-03 | Link Waldemar Gmbh Co | Intervertebral disc prosthesis |
DE4208115A1 (en) | 1992-03-13 | 1993-09-16 | Link Waldemar Gmbh Co | DISC ENDOPROTHESIS |
US5676701A (en) | 1993-01-14 | 1997-10-14 | Smith & Nephew, Inc. | Low wear artificial spinal disc |
US5397364A (en) * | 1993-10-12 | 1995-03-14 | Danek Medical, Inc. | Anterior interbody fusion device |
US5674296A (en) | 1994-11-14 | 1997-10-07 | Spinal Dynamics Corporation | Human spinal disc prosthesis |
EP1230902A1 (en) | 1996-11-15 | 2002-08-14 | Advanced Bio Surfaces, Inc. | Biomaterial system for in situ tissue repair |
US6146421A (en) * | 1997-08-04 | 2000-11-14 | Gordon, Maya, Roberts And Thomas, Number 1, Llc | Multiple axis intervertebral prosthesis |
US5888226A (en) | 1997-11-12 | 1999-03-30 | Rogozinski; Chaim | Intervertebral prosthetic disc |
US5899941A (en) * | 1997-12-09 | 1999-05-04 | Chubu Bearing Kabushiki Kaisha | Artificial intervertebral disk |
FR2772594B1 (en) | 1997-12-19 | 2000-05-05 | Henry Graf | REAR PARTIAL DISCAL PROSTHESIS |
ES2163216T3 (en) | 1998-03-13 | 2002-01-16 | Link Waldemar Gmbh Co | ENDOPROTESIS GAME FOR INTERVERTEBRAL DISCS. |
US6231609B1 (en) | 1998-07-09 | 2001-05-15 | Hamid M. Mehdizadeh | Disc replacement prosthesis |
US5928284A (en) | 1998-07-09 | 1999-07-27 | Mehdizadeh; Hamid M. | Disc replacement prosthesis |
US6113638A (en) | 1999-02-26 | 2000-09-05 | Williams; Lytton A. | Method and apparatus for intervertebral implant anchorage |
EP1057462B1 (en) | 1999-05-21 | 2003-04-02 | Waldemar Link (GmbH & Co.) | Intervertebral endoprosthesis with a toothed connection plate |
ATE388677T1 (en) | 1999-07-02 | 2008-03-15 | Spine Solutions Inc | INTERVERBARY IMPLANT |
US7201776B2 (en) | 1999-10-08 | 2007-04-10 | Ferree Bret A | Artificial intervertebral disc replacements with endplates |
US6875235B2 (en) | 1999-10-08 | 2005-04-05 | Bret A. Ferree | Prosthetic joints with contained compressible resilient members |
FR2805733B1 (en) | 2000-03-03 | 2002-06-07 | Scient X | DISC PROSTHESIS FOR CERVICAL VERTEBRUS |
FR2805985B1 (en) | 2000-03-10 | 2003-02-07 | Eurosurgical | INTERVERTEBRAL DISK PROSTHESIS |
ATE390099T1 (en) | 2000-04-04 | 2008-04-15 | Link Spine Group Inc | INTERVERBEL PLASTIC IMPLANT |
US6478800B1 (en) | 2000-05-08 | 2002-11-12 | Depuy Acromed, Inc. | Medical installation tool |
EP1250898A1 (en) | 2001-04-05 | 2002-10-23 | Waldemar Link (GmbH & Co.) | Intervertebral disc prosthesis system |
US6607558B2 (en) | 2001-07-03 | 2003-08-19 | Axiomed Spine Corporation | Artificial disc |
DE50114037D1 (en) | 2001-08-24 | 2008-07-31 | Zimmer Gmbh | Artificial disc |
EP1287795B1 (en) | 2001-08-24 | 2008-06-18 | Zimmer GmbH | Artificial spinal disc |
GB0126467D0 (en) | 2001-11-03 | 2002-01-02 | Accentus Plc | Deposition of coatings on substrates |
US6740118B2 (en) * | 2002-01-09 | 2004-05-25 | Sdgi Holdings, Inc. | Intervertebral prosthetic joint |
DE50210270D1 (en) | 2002-03-12 | 2007-07-19 | Cervitech Inc | Intervertebral prosthesis, especially for the cervical spine |
EP1344507A1 (en) | 2002-03-12 | 2003-09-17 | Waldemar Link (GmbH & Co.) | Intervertebral prosthesis for the cervical spine |
EP1344506A1 (en) | 2002-03-12 | 2003-09-17 | Waldemar Link (GmbH & Co.) | Intervertebral prosthesis for the cervical spine |
RU2303422C2 (en) | 2002-03-12 | 2007-07-27 | Сервитек Инк. | Intervertebral prosthesis and system of intervertebral prostheses, in peculiar case, for cervical department of vertebral column |
AU2003228391A1 (en) | 2002-03-30 | 2003-10-20 | Cool Brace | Intervertebral device and method of use |
US20030195631A1 (en) | 2002-04-12 | 2003-10-16 | Ferree Bret A. | Shape-memory spacers for artificial disc replacements |
US8038713B2 (en) | 2002-04-23 | 2011-10-18 | Spinecore, Inc. | Two-component artificial disc replacements |
US20080027548A9 (en) | 2002-04-12 | 2008-01-31 | Ferree Bret A | Spacerless artificial disc replacements |
US20040030390A1 (en) | 2002-04-23 | 2004-02-12 | Ferree Bret A. | Intradiscal component installation apparatus and methods |
US20030233148A1 (en) | 2002-04-23 | 2003-12-18 | Ferree Bret A. | Modular components to improve the fit of artificial disc replacements |
US6706068B2 (en) | 2002-04-23 | 2004-03-16 | Bret A. Ferree | Artificial disc replacements with natural kinematics |
US20040030391A1 (en) | 2002-04-24 | 2004-02-12 | Bret Ferree | Artificial intervertebral disc spacers |
US6960232B2 (en) | 2002-04-25 | 2005-11-01 | Blackstone Medical, Inc. | Artificial intervertebral disc |
US7338525B2 (en) | 2002-04-30 | 2008-03-04 | Ferree Bret A | Methods and apparatus for preventing the migration of intradiscal devices |
US7066958B2 (en) | 2002-05-10 | 2006-06-27 | Ferree Bret A | Prosthetic components with partially contained compressible resilient members |
US7001433B2 (en) | 2002-05-23 | 2006-02-21 | Pioneer Laboratories, Inc. | Artificial intervertebral disc device |
US6793678B2 (en) | 2002-06-27 | 2004-09-21 | Depuy Acromed, Inc. | Prosthetic intervertebral motion disc having dampening |
DE10242331B4 (en) | 2002-09-12 | 2005-10-20 | Biedermann Motech Gmbh | Placeholder for vertebral bodies or intervertebral discs |
DE10247762A1 (en) | 2002-10-14 | 2004-04-22 | Waldemar Link (Gmbh & Co.) | Intervertebral prosthesis |
AU2003286531A1 (en) * | 2002-10-21 | 2004-05-13 | 3Hbfm, Llc | Intervertebral disk prosthesis |
US7083649B2 (en) * | 2002-10-29 | 2006-08-01 | St. Francis Medical Technologies, Inc. | Artificial vertebral disk replacement implant with translating pivot point |
EP1417940A1 (en) | 2002-11-08 | 2004-05-12 | Waldemar Link (GmbH & Co.) | Vertebral prosthesis |
US7204852B2 (en) * | 2002-12-13 | 2007-04-17 | Spine Solutions, Inc. | Intervertebral implant, insertion tool and method of inserting same |
US7815679B2 (en) | 2003-01-06 | 2010-10-19 | Cardo Medical, Inc. | Modular motion preservation artificial spinal joint assembly |
JP2004283714A (en) * | 2003-03-20 | 2004-10-14 | Fujitsu Display Technologies Corp | Liquid delivery dispenser |
US7105024B2 (en) | 2003-05-06 | 2006-09-12 | Aesculap Ii, Inc. | Artificial intervertebral disc |
US7621956B2 (en) | 2003-07-31 | 2009-11-24 | Globus Medical, Inc. | Prosthetic spinal disc replacement |
US7794465B2 (en) * | 2003-09-10 | 2010-09-14 | Warsaw Orthopedic, Inc. | Artificial spinal discs and associated implantation instruments and methods |
FR2865629B1 (en) * | 2004-02-04 | 2007-01-26 | Ldr Medical | INTERVERTEBRAL DISC PROSTHESIS |
US7115144B2 (en) * | 2004-03-02 | 2006-10-03 | Joint Synergy, Llc | Spinal implant |
US7780731B2 (en) * | 2004-11-26 | 2010-08-24 | Spine Solutions, Inc. | Intervertebral implant |
US7927373B2 (en) | 2005-10-31 | 2011-04-19 | Depuy Spine, Inc. | Intervertebral disc prosthesis |
-
2005
- 2005-10-31 US US11/264,471 patent/US7927373B2/en active Active
-
2006
- 2006-04-07 US US11/399,903 patent/US20070100455A1/en not_active Abandoned
- 2006-05-12 US US11/432,908 patent/US7909876B2/en active Active
-
2007
- 2007-03-30 WO PCT/US2007/008248 patent/WO2007117425A2/en active Application Filing
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6039763A (en) * | 1998-10-27 | 2000-03-21 | Disc Replacement Technologies, Inc. | Articulating spinal disc prosthesis |
US6368350B1 (en) * | 1999-03-11 | 2002-04-09 | Sulzer Spine-Tech Inc. | Intervertebral disc prosthesis and method |
US6520996B1 (en) * | 1999-06-04 | 2003-02-18 | Depuy Acromed, Incorporated | Orthopedic implant |
US6790233B2 (en) * | 2001-05-01 | 2004-09-14 | Amedica Corporation | Radiolucent spinal fusion cage |
US6758862B2 (en) * | 2002-03-21 | 2004-07-06 | Sdgi Holdings, Inc. | Vertebral body and disc space replacement devices |
US20050165485A1 (en) * | 2004-01-27 | 2005-07-28 | Sdgi Holdings, Inc. | Hybrid intervertebral disc system |
Cited By (65)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9333095B2 (en) | 2001-05-04 | 2016-05-10 | Ldr Medical | Intervertebral disc prosthesis, surgical methods, and fitting tools |
US8267999B2 (en) | 2002-11-05 | 2012-09-18 | Ldr Medical | Intervertebral disc prosthesis |
US11957598B2 (en) | 2004-02-04 | 2024-04-16 | Ldr Medical | Intervertebral disc prosthesis |
US10603185B2 (en) | 2004-02-04 | 2020-03-31 | Ldr Medical | Intervertebral disc prosthesis |
US8858635B2 (en) | 2004-02-04 | 2014-10-14 | Ldr Medical | Intervertebral disc prosthesis |
US8002835B2 (en) | 2004-04-28 | 2011-08-23 | Ldr Medical | Intervertebral disc prosthesis |
US11806244B2 (en) * | 2004-05-13 | 2023-11-07 | Moskowitz Family Llc | Artificial cervical and lumbar disc system |
US11478359B2 (en) * | 2004-05-13 | 2022-10-25 | Moskowitz Family Llc | Artificial disc system |
US20220062002A1 (en) * | 2004-05-13 | 2022-03-03 | Moskowitz Family Llc | Artificial cervical and lumbar disc system |
US11083591B2 (en) | 2004-05-13 | 2021-08-10 | Moskowitz Family Llc | Artificial cervical and lumbar disc system |
US10610371B2 (en) * | 2004-05-13 | 2020-04-07 | Moskowitz Family Llc | Artificial cervical and lumbar discs, disc plate insertion gun for performing sequential single plate intervertebral implantation enabling symmetric bi-disc plate alignment for interplate mobile core placement |
US20180140431A1 (en) * | 2004-05-13 | 2018-05-24 | Nathan C. Moskowitz | Artificial cervical and lumbar discs, disc plate insertion gun for performing sequential single plate intervertebral implantation enabling symmetric bi-disc plate alignment for interplate mobile core placement |
US8257439B2 (en) | 2004-12-22 | 2012-09-04 | Ldr Medical | Intervertebral disc prosthesis |
US7695516B2 (en) | 2004-12-22 | 2010-04-13 | Ldr Medical | Intervertebral disc prosthesis |
US10226355B2 (en) | 2004-12-22 | 2019-03-12 | Ldr Medical | Intervertebral disc prosthesis |
US10350088B2 (en) | 2005-06-29 | 2019-07-16 | Ldr Medical | Instrumentation and methods for inserting an intervertebral disc prosthesis |
US8439931B2 (en) | 2005-06-29 | 2013-05-14 | Ldr Medical | Instrumentation and methods for inserting an intervertebral disc prosthesis |
US7842088B2 (en) | 2005-09-23 | 2010-11-30 | Ldr Medical | Intervertebral disc prosthesis |
US20070073404A1 (en) * | 2005-09-23 | 2007-03-29 | Ralph Rashbaum | Intervertebral disc prosthesis |
US11872138B2 (en) | 2005-09-23 | 2024-01-16 | Ldr Medical | Intervertebral disc prosthesis |
US10492919B2 (en) | 2005-09-23 | 2019-12-03 | Ldr Medical | Intervertebral disc prosthesis |
US7909876B2 (en) | 2005-10-31 | 2011-03-22 | Depuy Spine, Inc. | Intervertebral disc prosthesis with shear-limiting core |
US7927373B2 (en) | 2005-10-31 | 2011-04-19 | Depuy Spine, Inc. | Intervertebral disc prosthesis |
US20070100453A1 (en) * | 2005-10-31 | 2007-05-03 | Depuy Spine, Inc. | Intervertebral disc prosthesis |
US9265618B2 (en) | 2005-11-30 | 2016-02-23 | Ldr Medical | Intervertebral disc prosthesis and instrumentation for insertion of the prosthesis between the vertebrae |
US11452619B2 (en) * | 2006-04-04 | 2022-09-27 | Moskowitz Family Llc | Artificial disc system |
US11135072B2 (en) | 2006-04-04 | 2021-10-05 | Moskowitz Family Llc | Artificial disc system |
US20220241093A1 (en) * | 2006-04-04 | 2022-08-04 | Moskowitz Family Llc | Artificial disc system |
US11771567B2 (en) | 2006-04-04 | 2023-10-03 | Moskowitz Family Llc | Artificial disc system |
US10080667B2 (en) | 2006-09-15 | 2018-09-25 | Pioneer Surgical Technology, Inc. | Intervertebral disc implant |
US20100280619A1 (en) * | 2006-09-15 | 2010-11-04 | Hansen Yuan | Systems and methods for sizing, inserting and securing an implant in intervertebral space |
US8377133B2 (en) | 2006-09-15 | 2013-02-19 | Pioneer Surgical Technology, Inc. | Systems and methods for sizing, inserting and securing an implant in intervertebral space |
US20100016974A1 (en) * | 2006-09-15 | 2010-01-21 | Janowski Brian P | Systems and methods for securing an implant in intervertebral space |
US8715350B2 (en) | 2006-09-15 | 2014-05-06 | Pioneer Surgical Technology, Inc. | Systems and methods for securing an implant in intervertebral space |
US9233011B2 (en) | 2006-09-15 | 2016-01-12 | Pioneer Surgical Technology, Inc. | Systems and apparatuses for inserting an implant in intervertebral space |
US8597357B2 (en) | 2006-09-15 | 2013-12-03 | Pioneer Surgical Technology, Inc. | System and method for sizing, inserting and securing artificial disc in intervertebral space |
US9693872B2 (en) | 2006-09-15 | 2017-07-04 | Pioneer Surgical Technology, Inc. | Intervertebral disc implant |
US20080103598A1 (en) * | 2006-09-15 | 2008-05-01 | Trudeau Jeffrey L | System and Method for Sizing, Inserting and Securing Artificial Disc in Intervertebral Space |
US8465546B2 (en) | 2007-02-16 | 2013-06-18 | Ldr Medical | Intervertebral disc prosthesis insertion assemblies |
US10398574B2 (en) | 2007-02-16 | 2019-09-03 | Ldr Medical | Intervertebral disc prosthesis insertion assemblies |
US10188528B2 (en) | 2007-02-16 | 2019-01-29 | Ldr Medical | Interveterbral disc prosthesis insertion assemblies |
US10751187B2 (en) | 2007-06-08 | 2020-08-25 | Ldr Medical | Intersomatic cage, intervertebral prosthesis, anchoring device and implantation instruments |
US8343219B2 (en) | 2007-06-08 | 2013-01-01 | Ldr Medical | Intersomatic cage, intervertebral prosthesis, anchoring device and implantation instruments |
US8231676B2 (en) | 2007-09-17 | 2012-07-31 | Pioneer Surgical Technology, Inc. | Motion preserving artificial intervertebral disc device |
US20090240333A1 (en) * | 2007-09-17 | 2009-09-24 | Trudeau Jeffrey L | Motion Preserving Artificial Intervertebral Disc Device |
US20100241231A1 (en) * | 2009-02-20 | 2010-09-23 | Marino James F | Intervertebral fixation device |
US20100262244A1 (en) * | 2009-04-14 | 2010-10-14 | Warsaw Orthopedic, Inc. | Metal Coated Implant |
US9173748B2 (en) * | 2009-08-07 | 2015-11-03 | Ebi, Llc | Toroid-shaped spinal disc |
US20110035006A1 (en) * | 2009-08-07 | 2011-02-10 | Ebi, Llc | Toroid-Shaped Spinal Disc |
US10085845B2 (en) | 2010-04-09 | 2018-10-02 | Centinel Spine Llc | Intervertebral implant |
US8858636B2 (en) * | 2010-04-09 | 2014-10-14 | DePuy Synthes Products, LLC | Intervertebral implant |
US9333088B2 (en) | 2010-04-09 | 2016-05-10 | DePuy Synthes Products, Inc. | Intervertebral implant |
US9301853B2 (en) | 2010-04-09 | 2016-04-05 | DePuy Synthes Products, Inc. | Holder for implantation and extraction of prosthesis |
US20110251690A1 (en) * | 2010-04-09 | 2011-10-13 | Roger Berger | Intervertebral implant |
US11419734B2 (en) | 2010-04-09 | 2022-08-23 | Centinelspine, Llc | Intervertebral implant |
US20150051705A1 (en) * | 2010-08-31 | 2015-02-19 | Meditech Spine, Llc | Spinal Implants |
US10285823B2 (en) | 2010-08-31 | 2019-05-14 | Meditech Spine, Llc | Spinal implants |
US9427329B2 (en) * | 2010-08-31 | 2016-08-30 | Meditech Spine, Llc | Spinal implants |
US9814558B2 (en) | 2011-07-13 | 2017-11-14 | Vivex Biomedical, Inc. | Spinal implants with stem cells |
WO2013009837A1 (en) * | 2011-07-13 | 2013-01-17 | Amendia, Inc. | Spinal implants with stem cells |
US9757223B2 (en) | 2011-07-13 | 2017-09-12 | Vivex Biomedical, Inc. | Spinal implants with stem cells |
US9289312B2 (en) | 2011-07-13 | 2016-03-22 | Vivex Biomedical, Inc. | Spinal implants with stem cells |
US11147682B2 (en) | 2017-09-08 | 2021-10-19 | Pioneer Surgical Technology, Inc. | Intervertebral implants, instruments, and methods |
USD968613S1 (en) | 2017-10-09 | 2022-11-01 | Pioneer Surgical Technology, Inc. | Intervertebral implant |
USD907771S1 (en) | 2017-10-09 | 2021-01-12 | Pioneer Surgical Technology, Inc. | Intervertebral implant |
Also Published As
Publication number | Publication date |
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US20070100453A1 (en) | 2007-05-03 |
US20070100456A1 (en) | 2007-05-03 |
WO2007117425A2 (en) | 2007-10-18 |
WO2007117425A3 (en) | 2008-06-12 |
US7909876B2 (en) | 2011-03-22 |
US7927373B2 (en) | 2011-04-19 |
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