US20060100663A1 - Embolic basket - Google Patents

Embolic basket Download PDF

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Publication number
US20060100663A1
US20060100663A1 US11/317,930 US31793005A US2006100663A1 US 20060100663 A1 US20060100663 A1 US 20060100663A1 US 31793005 A US31793005 A US 31793005A US 2006100663 A1 US2006100663 A1 US 2006100663A1
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US
United States
Prior art keywords
basket
coil
elongate member
proximal
section
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
US11/317,930
Inventor
Olin Palmer
Christopher Shen
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Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/469,431 external-priority patent/US6402771B1/en
Application filed by Individual filed Critical Individual
Priority to US11/317,930 priority Critical patent/US20060100663A1/en
Publication of US20060100663A1 publication Critical patent/US20060100663A1/en
Priority to US12/111,911 priority patent/US8137377B2/en
Abandoned legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/22Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
    • A61B17/221Gripping devices in the form of loops or baskets for gripping calculi or similar types of obstructions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/01Filters implantable into blood vessels
    • A61F2/013Distal protection devices, i.e. devices placed distally in combination with another endovascular procedure, e.g. angioplasty or stenting
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M29/00Dilators with or without means for introducing media, e.g. remedies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B2017/00526Methods of manufacturing
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/22Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
    • A61B17/221Gripping devices in the form of loops or baskets for gripping calculi or similar types of obstructions
    • A61B2017/2212Gripping devices in the form of loops or baskets for gripping calculi or similar types of obstructions having a closed distal end, e.g. a loop
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/01Filters implantable into blood vessels
    • A61F2002/016Filters implantable into blood vessels made from wire-like elements
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/01Filters implantable into blood vessels
    • A61F2002/018Filters implantable into blood vessels made from tubes or sheets of material, e.g. by etching or laser-cutting
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2230/00Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2230/0063Three-dimensional shapes
    • A61F2230/0097Harpoon-shaped

Definitions

  • the present invention relates generally to intravascular devices and systems and more particularly, basket devices which can be used to capture embolic material or thrombi found in blood vessels.
  • the intravascular basket device and system of the present invention is particularly useful when performing balloon angioplasty, stenting procedures, laser angioplasty or atherectomy in critical vessels where the release of embolic debris into the bloodstream can occlude the flow of oxygenated blood to the brain or other vital organs, which can cause devastating consequences to the patient.
  • the basket device is also suited for the removal of clots adhering to vessel walls.
  • the device is also suitable for removal of misplaced coils or other foreign material. While the basket device and system of the present invention is particularly useful in the cerebral vasculature and neurovasculature, the invention can be used in conjunction with any vascular interventional procedure in which there is an embolic risk.
  • the basket device can be used in any region of the body where removal of debris or foreign material is indicated. Having a patterned body cut from a single tube element, the basket device allows for an enhanced radial opening into the basket body that provides for greater ease of embolic capture. Additionally the patterned body embodies greater stability during use by resisting the natural tendency to collapse as seen in most prior art snares during a typical operation.
  • a variety of non-surgical interventional procedures have been developed over the years for opening stenosed or occluded blood vessels in a patient caused by the build-up of plaque or other substances on the wall of the blood vessel.
  • Such procedures usually involve the remote introduction of the interventional device into the lumen of the artery, usually through a catheter.
  • a guiding catheter or sheath is percutaneously introduced into the cardiovascular system of a patient through the femoral artery and advanced, for example, through the vasculature until the distal end of the guiding catheter is in the common carotid artery.
  • a guidewire and a dilatation catheter having a balloon on the distal end are introduced through the guiding catheter with the guidewire sliding within the dilatation catheter.
  • the guidewire is first advanced out of the guiding catheter into the patient's carotid vasculature and is directed across the arterial lesion.
  • the dilatation catheter is subsequently advanced over the previously advanced guidewire until the dilatation balloon is properly positioned across the arterial lesion.
  • the expandable balloon is inflated to a predetermined size with a radiopaque liquid at relatively high pressures to radially compress the atherosclerotic plaque of the lesion against the inside of the artery wall and thereby dilate the lumen of the artery.
  • the balloon is then deflated to a small profile so that the dilatation catheter can be withdrawn from the patient's vasculature and the blood flow resumed through the dilated artery.
  • the above-described procedure is typical, it is not the only method used in angioplasty.
  • Atherectomy is yet another method of treating a stenosed blood vessel in which cutting blades are rotated to shave the deposited plaque from the arterial wall.
  • a vacuum catheter is usually used to capture the shaved plaque or thrombus from the blood stream during this procedure.
  • abrupt reclosure may occur or restenosis of the artery may develop over time, which may require another angioplasty procedure, a surgical bypass operation, or some other method of repairing or strengthening the area.
  • a physician can implant an intravascular prosthesis for maintaining vascular patency, commonly known as a stent, inside the artery across the lesion.
  • the stent is crimped tightly onto the balloon portion of the catheter and transported in its delivery diameter through the patient's vasculature. At the deployment site, the stent is expanded to a larger diameter, often by inflating the balloon portion of the catheter.
  • a first type of stent is expandable upon application of a controlled force, as described above, through the inflation of the balloon portion of a dilatation catheter which, upon inflation of the balloon or other expansion means, expands the compressed stent to a larger diameter to be left in place within the artery at the target site.
  • a second type of stent is a self-expanding stent formed from, for example, shape memory metals or super-elastic nickel-titanum (NiTi) alloys, which will automatically expand from a compressed state when the stent is advanced out of the distal end of the delivery catheter into the body lumen.
  • NiTi super-elastic nickel-titanum
  • fragmented clot may be incomplete, also resulting in emboli and distal occlusions, and further, access through tortuous lumens may prove difficult.
  • Laser-based disruption devices employ the photo-acoustic effect to fragment clot. Local disruption may open up a proximal occlusion but also may cause significant distal emboli.
  • thrombectomy and foreign matter removal devices have been disclosed in the art.
  • such devices have been found to have structures which are either highly complex such as with multiple components or highly convoluted geometry or lacking in sufficient or effective expansion and retraction capabilities.
  • Disadvantages associated with the devices having highly complex structure such as with multiple components or highly convoluted geometry include difficulty in manufacturability as well as use in conjunction with microcatheters.
  • Other devices with less coverage can pull through clots due in part to the lack of experience in using the same or otherwise lack an expanded profile that is adequate to capture clots or foreign bodies.
  • Thrombo-embolic materials can be friable, amorphous, and/or lubricious in nature contributing to this difficulty.
  • Most current therapies rely on grasping, fragmenting, or dissolving the blood-based obstructions.
  • the grasping devices are the loop snares and the wire basket snares. These devices may have limited effectiveness, due in part to the lack of encapsulation. Objects are difficult to grasp within these devices, and friable objects, e.g. blood-based blockages, tend to fragment when grasped or pulled, introducing multiple emboli.
  • Lytic drugs are also used to dissolve blood-based obstructions. These typically have the disadvantages of lengthy treatment/infusion times to remove the obstruction (>3 hrs.), production of emboli, and the potential for systemic iatrogenic bleeding as a side effect of the drug usage. Also, these drugs are not typically effective in removing obstructions that are not blood-based.
  • the basket devices should be capable of capturing any naturally occurring embolic debris or that which may be released into the bloodstream during an interventional treatment, while minimizing profile during delivery and maximizing coverage when deployed to safely contain the debris until the basket device is removed from the patient's vasculature.
  • the devices should embody an expanded profile that presents a consistent radial opening that completely occupies the vessel at the repair site as well as structure for effectively resisting collapse.
  • such devices should be relatively easy to deploy and remove from the patient's vasculature and also should be capable of being used in narrow and very distal vasculature such as the cerebral vasculature. The following invention addresses these needs.
  • the present invention is directed towards a basket for removing undesired material or objects and restoring patency of blood vessels.
  • the basket is a linked or monolithic framework of thin struts that is radially expansible.
  • the basket of the present invention embodies a structure that provides a consistent radial opening as well as improved radial and angular resistance to collapse. That is, as the device is pulled such as through a vessel, the entrance thereto will not fall back or tip over.
  • the basket device maintains clearance in its interior space along its length allowing the material or objects to enter and be captured.
  • the basket includes struts with very small widths and thicknesses and rings with very small widths and thicknesses but large expansion ratios. It is particularly beneficial to manufacture the basket from a piece of tube stock, as opposed to prior art wire baskets, because the resulting basket is more ordered upon compression, returns to its expanded state more reliably and is quicker to manufacture.
  • the body of the basket device is defined by a plurality of openings bounded by generally longitudinally and generally circumferentially extending members. A proximally extending member is attached to an elongate wire and the assembly is contemplated to be used in conjunction with a generally tubular delivery catheter.
  • the body provides enhanced stability at the proximal transition between the wire and the proximally extending members because the design may allow for varying lengths and widths of the proximally extending members.
  • the basket may be manufactured from a single tubular element or from a sheet to form a desired configuration.
  • the intent of the invention is to provide a structure that has the capacity to engage, encompass and retain naturally occurring or foreign bodies while having a minimal profile that can traverse easily and repeatedly through a standard microcatheter across tortuous anatomy.
  • the device embodies superior flexibility to be deployed and retrieved consistently across difficult anatomy while being able to retain captured material.
  • the inner diameter of the device is heat-set to a pre-determined size. It is envisioned that there be a family of devices that have varying strut lengths, thicknesses, flexibility, and diameters as deemed appropriate for the specific type of vascular or non-vascular setting for which the device is to be used.
  • the basket device is self-expanding and includes a mid-section that forms a generally tubular profile.
  • the proximally extending member projects as an axial extension of a line at the surface of the cylinder generally defining the substantially tubular portion to thereby provide an unobstructed opening at the proximal end of the basket.
  • a terminal (i.e., distal) end of the basket device can be closed or constricted so as to form a pocket for receiving emboli or thrombotic debris.
  • the basket device can assume a number of forms.
  • the basket device of the present invention embodies first and second end portions, and a mid-section having a plurality of consecutive rings, each ring having a plurality of generally straight members configured in an alternating V-pattern providing a plurality of proximal and distal apices.
  • the intravascular basket device has a mid-section defined by a single ring also having generally straight members configured in an alternating V-pattern providing four apices on each of the mid-section proximal and distal ends.
  • the mid-section may embody a double ring design configured in a four apex pattern.
  • the basket device mid-section may include rings having different lengths or, in the alternative, include a proximal section having different lengths.
  • the plurality of members can be curved, S-shaped, angled, tapered etc. rather than straight or can be a combination of straight and curved, angled, tapered or other combinations etc.
  • the present invention embodies a tip for an endovascular device including an atraumatic soft coil for preventing damage to tissue and facilitates advanceability.
  • the tip further includes multiple layers of coiled material to enhance these objectives as well as to provide stiffness variations.
  • FIG. 1 is a side view, partially in cross-section, of a vessel occluded by debris and a distal portion of a delivery catheter and intravascular snare assembly of the present invention positioned proximate the debris;
  • FIG. 2 is a side view, partially in cross-section, of the intravascular basket as deployed within the vessel of FIG. 1 ;
  • FIG. 3 is a plan view, depicting a pattern of a preferred embodiment of an intravascular basket of the present invention as if the basket was cut longitudinally and unrolled to show its pattern in a flat configuration;
  • FIG. 3 a is an enlarged view of a portion of an intravascular basket of the present invention, depicting curvilinear members defining the basket;
  • FIG. 3 b is an enlarged view of a portion of an intravascular basket of the present invention, depicting a filler member positioned between other members defining the basket;
  • FIG. 4 is a plan view, depicting an unrolled pattern of a second alternative embodiment of an intravascular basket of the present invention.
  • FIG. 5 is a plan view, depicting an unrolled pattern of a third alternative embodiment of an intravascular basket of the present invention.
  • FIG. 6 is a plan view, depicting an unrolled pattern of a fourth alternative embodiment of an intravascular basket of the present invention.
  • FIG. 7 is a plan view, depicting an unrolled pattern of a fifth alternative embodiment of an intravascular basket of the present invention.
  • FIG. 8 is a plan view, depicting an elongate member of the present invention.
  • FIG. 9 is a side view, partially in cross-section, depicting a plurality of coils configured about a distal end portion of the elongate members in combination with a basket device of the present invention
  • FIG. 10 is a cross-sectional view, depicting the assembly of FIG. 9 taken along lines 10 - 10 ;
  • FIG. 11 is a side view, partially in cross-section, depicting a distal end portion of a tip of the basket device of the present invention.
  • FIG. 12 is a cross-sectional view, depicting a portion of the assembly of FIG. 11 taken along lines 12 - 12 ;
  • FIG. 13 is a cross-sectional view, depicting the assembly of FIG. 11 taken along lines 13 - 13 ;
  • FIG. 14 is a perspective side view, depicting the device pattern projected onto the tubing which it will be cut from to produce the basket device of FIG. 3 ;
  • FIG. 15 is a perspective bottom view, depicting the device pattern projected onto the tubing which it will be cut from to produce the basket device of FIG. 3 .
  • the basket device 20 is adapted to provide more consistent and improved radial opening as well as enhanced angular resistance to collapse. Moreover, the basket device 20 of the present invention is configured to facilitate the maintenance of clearance in its interior space along its length allowing the material or objects to enter and be captured. Furthermore, since it is contemplated that the basket device 20 be manufactured from a tubular member to form elements with very small widths and thicknesses, the device is thus more easily packed to a relatively smaller diameter and inherently embodies high longitudinal flexibility.
  • the basket device 20 ( FIG. 2 ) of the present invention includes a body 22 having a proximal end portion 24 and a distal end portion 26 .
  • the proximal end portion 24 is intended to be affixed to a terminal end portion of an elongate member 30 (i.e., wire; described in more detail below).
  • the body 22 of the basket device 20 is generally tubular with a proximally directed opening 32 and a generally closed terminal end 34 to thereby form a basket for receiving embolus, stones, thrombus and foreign bodies found in vasculature or other body cavities.
  • the basket device 20 for intravascular uses is contemplated to be used in conjunction with a generally tubular delivery catheter 40 , such as a microcatheter. Additionally, it is contemplated that a conventional guide catheter (not shown) be used in combination with the delivery catheter 40 loaded with a basket device 20 .
  • a guide catheter (not shown) is employed to provide a guide within a patient's vasculature through which the delivery catheter 40 is inserted.
  • a proximal end of the guide may include a rotating hemostatic valve or “Y” adapter fitted with sealing hemostatic valves.
  • the basket device 20 is intended to be self-expandable, however, it is possible to employ an expandable member such as a balloon catheter (not shown) to radially expand the basket device that is not self-expandable, but rather must be deformed to assume an expanded configuration.
  • an expandable member such as a balloon catheter (not shown) to radially expand the basket device that is not self-expandable, but rather must be deformed to assume an expanded configuration.
  • the body 22 of the basket device 20 is placed proximally in a compressed configuration coaxially within an internal bore of the generally tubular delivery catheter 40 .
  • the longitudinally extending elongate member 30 which is attached to the proximal end 24 of the body 22 , is likewise coaxially received within the delivery catheter 40 .
  • Both the body 22 and elongate member 30 are slidable within the delivery catheter 40 and accordingly, the delivery catheter 40 and the basket device 20 can be displaced longitudinally with respect to each other.
  • the basket device/delivery catheter assembly 42 is introduced into a patient's vasculature using conventional means such as the Seldinger technique. Sometimes, a cutdown is made to gain access to the patient's vasculature. Using standard endovascular techniques, the emboli in the vasculature is located. The emboli is crossed with an appropriate guidewire (not shown) then the delivery catheter 40 . If the vessel is occluded, contrast is injected distal to the occlusion to map the distal vessels. The tip 48 of the delivery catheter 40 is positioned one basket length or slightly more beyond the emboli. The guidewire is removed and the basket device 20 is loaded through a rear hub (not shown) of the delivery catheter 20 with the assistance of an introducer sheath (not shown). The basket device 20 is advanced 30-40 cm and the introducer sheath is then removed.
  • the basket device 20 is advanced until the tip 26 of the basket is positioned at the distal end of the delivery catheter 40 .
  • Radioopaque markers are located on either side of the basket so that the operator can see when the basket is located just inside of the end of the delivery catheter 40 .
  • the basket device 20 is held in place by the operator holding the elongate member 30 still while the catheter 40 is retracted to allow the basket device to expand. Holding the basket device 20 in place, the catheter 40 is pulled back until it is proximal to the emboli 46 . Then, the basket device is drawn back allowing the emboli 46 to enter the basket device 20 .
  • the entire system can be drawn back holding relative positions between the basket device 20 and the catheter 40 .
  • This step can be assisted with a “stuttering” technique where the basket device 20 is drawn out a small amount, perhaps 2 mm, then the elongate member 30 is advanced back perhaps 1 mm to allow the mouth of the basket device 20 to re-open fully, thereby assisting clot or emboli entry into the basket. Then the system is drawn out another 1 mm. This is repeated until the basket device 20 has traversed a distance about its own length.
  • blood flow control may be used during extraction.
  • a guiding catheter with a flow control device such as an elastomeric balloon at the distal tip may be employed to slow or stop blood flow past the device during retrieval.
  • the basket device 20 can be moved back and forth past the coil in an iterative attempt to engage the coil in the struts of the basket. When this has occurred, the catheter 40 can be advanced causing the basket to collapse and pinch the coil, locking it into one of the openings of the basket device 20 . If the emboli is not radiopaque, its position may be checked by a contrast injection and noting a “filling defect.” Also, the radiopaque tip 26 of basket device 20 can be observed under fluoroscopy during this process. A pulsing motion can indicate restored flow.
  • the system 42 is then drawn back until the distal end of a proximal device marker coil (described below) is at the tip of the guide.
  • a large syringe perhaps 60 cc, is attached to the guide catheter at the “Y” adapter on the hub.
  • the guide catheter is aspirated as the basket device 20 and emboli 46 are drawn into the guide. Aspiration is maintained until the basket device 20 is fully into the “Y” adapter of the guide catheter, but the basket device 20 is not yet drawn through the hemostatic valve.
  • the “Y” adapter is detached and removed with the basket device in it, allowing a moment of bleed back through the guide to flush any loose emboli.
  • a second “Y” arm is attached to prevent excessive bleed back.
  • the guide is then flushed with saline and the entire procedure repeated as required to remove further emboli.
  • the body portion 22 of the basket device 20 self-expands within the vasculature and the resultant expansion profile provides a number of advantages.
  • the body 22 expands to conform to the repair site 44 . That is, the generally tubular profile of the body portion 22 substantially conforms to the walls defining the blood vessel 49 .
  • the basket device 20 can be sized such that upon full expansion it has a diameter smaller than the diameter of the blood vessel 49 if desired.
  • the expansion of the body 22 facilitates the maintenance of clearance in its interior space along its length allowing the material or objects 46 to enter and be captured and specifically provides a substantially unobstructed access to the proximally directed opening 32 to the body 22 .
  • members 50 and 51 leading to the opening 32 to the body 22 are angled or oriented so as to be adjacent to the walls defining the blood vessel 49 and are therefore substantially removed from the flow path to thereby provide an unobstructed opening 32 .
  • the basket device 20 is particularly well-suited to remove embolic or thrombotic debris 46 from the blood vessel 49 .
  • the basket device 20 can be withdrawn proximally so that the debris 46 can be captured by the body 22 of the basket device 20 .
  • a separate pusher mechanism (not shown) can be employed to push the debris 46 within the basket defined by the body portion 22 .
  • the system 42 can be removed from the patient's vasculature or the basket device 20 containing the debris 46 can first be pulled within the guide catheter (not shown) and then the assembly 42 removed from the target repair site 44 .
  • just the proximal end portion 24 of the basket device 20 can be cinched down to lock the debris without being fully pulled into the delivery catheter 40 .
  • thrombus or other blood-based material captured within the basket may be eliminated in a variety of ways.
  • the material may be drawn into the guide catheter with the aide of suction applied to the guide catheter, and removed from the body.
  • these materials may be removed from the occluded vessel and allowed to dissolve under natural or induced lytic processes.
  • the blood-based material may be inserted into other vasculature more tolerant of occlusion and released.
  • a basket 20 in a preferred embodiment of a basket pattern 125 shown as if it was cut longitudinally and unrolled to depict its pattern in a flat configuration, includes a proximal section 126 , mid-section 132 , and a distal section 127 .
  • the sections 126 , 132 and 127 together form a substantially tubular basket body 22 with a tapered distal end as will be developed further below.
  • the body 22 embodying such a pattern 125 be cut from a tubular member using a laser.
  • the body can be made from a flat sheet of nitinol and rolled into a tubular basket body.
  • the basket pattern 125 further includes an elongate member 30 extending proximally from a proximal end portion 53 of the basket body 22 .
  • each of the members defining the basket body 22 in this or other embodiments may have curved, arced, S-shaped, partially straight sections or other configurations (See FIG. 3 a , for eg.).
  • the body can further include branches 121 with an enlarged or angled terminal end ( FIG. 3 b ) which act as fillers between other members defining the body 20 . Such fillers 121 aid in providing a basket highly equipped to contain material.
  • the proximal section 126 of the basket 20 includes a proximal end 23 , a distal end 25 and a straight member section 128 .
  • the straight member section 128 includes a plurality of members 130 generally configured in a V-shape in that the members “fan out” or diverge in a distal direction. In this configuration, the straight members 130 lead to and aid in defining an opening 32 (see FIGS. 2 and 14 ) to the body 22 , when in its as-cut tubular configuration.
  • the members 130 of the straight member section 128 are pair-wise configured in a V-shape such that two proximal vertices 129 are formed where the members 130 proximally merge and four open-ended distal end points 131 are provided to define the distal end 25 of the member section 128 .
  • the straight member section 128 defines the entirety of the basket proximal section 126 , however, as will be subsequently discussed, in alternative embodiments, the proximal section 126 may include a plurality of straight member sections.
  • the two proximal vertices 129 of the member section 128 merge into two curved members 50 .
  • the curved members 50 converge proximally to form a tab 53 that may be connected to an elongate member 30 .
  • the mid-section 132 of the basket pattern 125 may be of a four apex design including a single ring 133 that defines the generally tubular mid-section 132 .
  • the ring 133 includes a plurality of straight members 136 configured in an alternating V-pattern forming a plurality of proximal apices 135 and distal apices 137 .
  • the ring 133 of the basket mid-section 132 may include eight straight members 136 converging end to end in an alternating V-pattern to form four proximal apices 135 and four distal apices 137 .
  • Each of the four proximal apices 135 merge into the open-ended distal end points 131 of the straight members 130 of the basket proximal section 126 .
  • intersection of the four straight members 130 of the basket proximal section 126 and the straight members 133 of the basket mid-section 132 at the proximal apices 135 define a plurality of diamond-shaped apertures 118 .
  • a single enlarged diamond-like aperture 116 located substantially within the basket proximal section 126 , is defined by the intersections at the proximal end of the basket proximal section 126 between the two curved members 50 and the proximal vertices 129 of the basket proximal section 126 and the intersections at distal end of the basket proximal section between the distal end points 131 of the proximal section 126 to the proximal apices 135 of the basket mid-section 132 .
  • the distal section 127 of the basket 20 includes a single straight member section 139 having straight members 140 in a V-shape configuration that “fans-in” (i.e., converge) distally.
  • the straight members 140 include four open-ended proximal ends 138 (the branches of the V-shape) at the distal apices 137 of the basket 20 mid-section 132 .
  • straight members converge to form two vertices 141 at the distally directed members 142 .
  • the junction between the two straight members 140 of the basket distal section 127 and the straight members 133 of the basket mid-section 132 at the distal apices 137 define a plurality of diamond-shaped apertures 120 .
  • the distally directed straight members 142 of the basket distal portion 127 may be joined together to form a substantially closed basket. This structure can be joined using soldering or by employing a coil (described herein below) that is wrapped about adjacent structures to form a soft tip.
  • the distally directed extensions 142 may also be trimmed to a desired length.
  • the basket device begins with a proximal elongate member linked to a series of divergent branches of increasing density covering successively smaller fractions of the tubular circumference.
  • the increasing density of the divergent branches wrap around the circumference from the side where the elongate member ends to form the tube.
  • Linked from the divergent branches is one or more ring segments in which an equal number of struts enter and exit at the joints.
  • Branching from the ring segment is a series of convergent branches of decreasing density covering successively larger fractions of the tubular circumference. This section is tapered down to the distal tip to reduce the required coverage area thus maintaining adequately small openings for encapsulation.
  • a basket pattern may be varied in a number of ways to produce a number of alternative embodiments of the current invention. From these alternative embodiments it will be understood that the lengths of the straight members of the mid-section rings may be varied accordingly to address any specific application requirement. Similarly, the lengths of the generally straight members of the member section of the proximal section may also be varied in length according to the desired design requirement. In order to have the device collapse evenly, all continuous (not recursive) paths from the first bifurcation to the last convergence of members must be of approximately the same length. Otherwise, during collapse the longer members are forced to buckle or the shorter members are forced to stretch to achieve a substantially linear constrained configuration.
  • the basket patterns 145 include a mid-section 148 having two rings 152 and 153 configured in a “four apex” design. Each ring 152 , 153 is defined by a plurality of connected vees to thereby define a ring having a generally serpentine pattern. A two ring design having a distal taper may provide enhanced clot capturing capabilities because of the smaller sized apertures located at the distal portions of the basket body 22 .
  • the rings 152 and 153 include straight members 155 and 159 having a first length.
  • FIGS. 4 and 6 the rings 152 and 153 include straight members 155 and 159 having a first length.
  • the rings 152 and 153 include straight members 170 and 174 having a second length that is longer than the first length of straight members 155 and 159 . Therefore, the rings 152 and 153 of the second and fourth embodiments are shorter in length than the rings 152 and 153 of the third and fifth embodiments. It is envisioned that the length of the rings of the third and fifth embodiments may be two or more times longer than the rings of the second and fourth embodiments and that there can be any number of rings.
  • each ring 152 includes proximal apices 154 and distal apices 156 and each ring 153 includes proximal apices 158 and distal apices 160 .
  • the ring 152 is connected to ring 153 at the connection 157 between apices 156 and 158 . Together rings 152 and 153 form the generally tubular mid-section 148 .
  • the basket patterns 145 of the second through fifth embodiments includes a proximal section 146 and a distal section 147 configured and connected to the mid-section 148 in a like manner as the first embodiment.
  • the two ring design of the basket patterns 145 allow for a distally tapering body 22 that provides for the capture of smaller emboli because the additional ring results in a body 22 having an increased number of apertures which are each smaller in size than those of the single ring design.
  • a first member section 150 includes straight members 151 having a first length
  • the first member section 150 includes straight members 181 having a second length that is shorter than the length of straight members 151 .
  • the change in the length of the members of the first member section 150 is intended to increase the radial strength of the device proximally. Therefore, the radial strength of the proximal transition of the device body 22 is increased which improves emboli capture by holding the device open and a shorter tab improves push by providing greater resistance to column buckling.
  • the basket device 20 may be configured having different mid-section 148 or proximal section 146 lengths or may be designed to include different numbers of apices within the mid-section.
  • the member 30 embodies a gradual or step-tapered core comprising a proximal section of 304V stainless steel and a distal section of nitinol or an equivalent material for the intended purpose.
  • a proximal portion 200 of the member 30 has a generally constant cross-sectional profile and a first diameter 201 .
  • the member 30 begins to taper in a gradual and consistent, alternatively in a step-tapered or in parabolic or other non-linear manner, from the first diameter 201 to a second diameter 203 along a distal end portion 204 .
  • a pair of longitudinally adjacent arranged coils 206 , 208 are employed to attach a proximal tab 214 of a basket device 20 to the distal end portion 204 of the elongate member 30 .
  • the first, proximal coil 206 is contemplated to be composed of 304V stainless steel, the first coil being soldered to the elongate wire 30 near its tapered portion 210 .
  • the second coil 208 is contemplated to embody a medical grade radiopaque wire, typically a platinum alloy such as about 90% platinum and 10% iridium alloy.
  • This second coil 208 which serves as a radiopaque marker, is soldered to the elongate member 30 near a distal end portion 212 of the first coil 206 .
  • the second coil 208 is soldered to the first coil 206 .
  • a proximal tab 214 of the basket device 20 is contained within the second coil 208 and is soldered 216 to the elongate member 30 .
  • the distal tip portion 220 embodies two partially coaxial coils 222 , 224 , the combination of which retains the distally directed extensions projecting from the body 22 of the basket device 20 .
  • the combination also provides a soft atraumatic tip with variable stiffness from softest distally to stiffer proximally. Varying the relative lengths of the tip and coils 222 , 224 results in creating changes in stiffness and thus, can be selected to provide the device with desired flexibility.
  • the inner coil 222 is comprised of nitinol or equivalent material, and begins at a proximal location 226 and extends to a distal location 228 .
  • the nitinol inner coil 222 provides kink resistance as well as creates a smooth stiffness transition from the tip of the basket portion of the basket device 20 .
  • the outer coil 224 is coaxially configured about a distal portion 230 of the inner coil 222 and is preferably comprised of 90% platinum and 10% iridium alloy or an equivalent combination of materials. As such, the outer coil 224 can operate as a radiopaque marker.
  • the distal tip portion 220 further includes a rounded terminal end 232 that provides a blunt atraumatic surface.
  • the terminal end 232 embodies a soldered joint which acts in retaining the helical configuration of the outer coil 224 .
  • the preferred embodiment of the present invention is relatively similar to the other embodiments disclosed and includes a four apex single ring pattern 125 .
  • the basket devices 20 of the present invention be cut from a tube 240 using a laser.
  • a specific pattern is programmed into the laser device and the laser is activated to cut the desired pattern into the tubular element 240 .
  • the excess tubular components are removed, thereby leaving a manufactured structure such as the basket pattern 125 shown in FIG. 3 , corresponding to the desired pattern.
  • a superelastic material such as nitinol is a material of choice for the basket device 20 .
  • post-processing such as surface treatment, burr removal, oxide removal and/or shape setting of the manufactured structure is performed. Heat treating is also performed for stress-relief of the device.
  • post-processing steps include taking an as-cut device and bead blasting the device with aluminum oxide blasting media.
  • the device is then inspected under a microscope for residual slag. If slag remains, the device is bead blasted again. Thereafter, the device is stress relieved in a molten salt bath without expanding.
  • the device is subsequently heat-expanded in a molten salt bath mounted on a suitable size mandrel. After heat expansion, surface oxidation is removed in an aqua regia bath.
  • nitinol is the material of choice, the nitinol is etched with HF solution to desired strut size resulting in desired softness.
  • the device is then mounted on a guidewire using coils and solder.
  • the post-processing may include deforming the pattern 125 and then joining together the distal end members 142 for the purpose of achieving a closed basket for receiving debris found in vasculature.
  • the pair of diverging members 50 define an opening 32 to the resultant basket and the elongate member 30 extends from a sidewall defined by the opening.
  • the basket devices of the present invention each provide improved radial opening compared to prior art loop snares since in an expanded state, the elongate member 30 is positioned substantially out of the flow path. Additionally, the device embodies improved resistance to radial and axial loads compared to prior art loop snares. Moreover, since less deformation is required to produce a desired basket pattern, in that, angles between members are provided by laser cutting rather than from local deformations, for example, there is potentially improved stress distribution along the basket devices of the present invention compared to prior art loop snares. Additionally, a greater reduction in radial profile can be achieved without sacrificing performance and in particular, the device can be used in conjunction with microcatheters. As such, the basket devices 20 of the present invention can be passed through narrow and tortuous vasculature. The applications of the present invention are more widespread than that of conventional snare devices because of greater retrieval characteristics while retaining the deliverability characteristics.
  • the above described invention is principally conceived to be operational for use in engaging for the purpose of displacing and/or removing material either foreign or native to the body, including partial or complete obstructions embolic and/or thrombotic in nature, from intraluminal or extraluminal spaces of the body including but not limited to intravascular and/or intra-arterial regions of the cerebral vasculature, as well as tubings, stents, or other objects that may or may not be internal to the body.
  • the purpose of the device is to restore functionality of the luminal space or systems dependent on the particular luminal space or as a method of producing any desired effect associated with the removal or displacement of undesirable material.
  • the intended delivery of the disclosed invention is by means of a commercially available catheter selected for its ability to access the desired location of engagement.
  • the invention may be optimized for specific locations or uses by means of sizing the individual elements in the design and/or the overall dimensions, as well as selection of materials, mesh configuration, number and relative geometry of component members to meet the requirements of the operational space. Optimizations may include tabs protruding from the sides of members to increase coverage of the open areas between members, offsetting vertices of joints to increase packing efficiency, or providing unconnected distal curved path. There may additionally be variations of the dimensions of length, thickness, and width of distal and proximal tabs for joining basket with delivery wire and distal tip to provide smooth stiffness transitions from tip to basket and basket to delivery wire. Such optimizations are means of adjusting operational attributes including: flexibility, applied circumferential force, engagement effectiveness, deliverability and traversal through tortuous vasculature, and volume of material to be engaged.
  • Alternate or additional materials for the basket portion of the device may include a shape memory polymer thermoset, elastomer, thermoplastic constituents such as nylon, or other metal either pure or alloyed, as well as composite materials such as a combination of glass, aramid, or carbon in a binding matrix.
  • a secondary mesh of the same or dissimilar material may be added to the basket.
  • the wire portion of the device can alternatively be made from a single metal or combination of metals for kink resistance and high flexibility. Either or both components may be tapered to give a transition in stiffness that is appropriate for the vessel in which the invention is to be delivered.
  • the distal tip of the device may incorporate concentric coils made of nitinol, stainless steel, or other metal or plastic to provide a soft flexible atraumatic end.
  • An alternate method of manufacture of the basket portion of the device may be photo etching, or metal or polymer injection molding or water jet cutting.
  • the device may employ any combination of coatings, agents, or features including those that result from material addition or subtraction to create grooves, bumps, three dimensional patterns, and textures on inner and/or outer surfaces or any combination thereof to promote desired properties such as adherence of materials to be engaged, radiopacity, and low friction between the device and the vessel wall or microcatheter lumen.
  • the invention is deliverable to remote regions of the vasculature by gaining access through the use of a guidewire and microcatheter in the vasculature and subsequent deployment of the invention through the lumen of the microcatheter.
  • the device In a vessel in which flow is impeded or obstructed by material and/or objects including those formed by the body such as blood clot, the device is deployed by withdrawing the microcatheter relative to the elongate wire and basket. Engagement occurs as the system composed of the invention is pulled proximal, causing the basket to encompass the material. After the material has been engaged, removal of the material is accomplished by withdrawing the system into a guide catheter lumen through which the microcatheter is passed with or without simultaneously pulling fluid through the guide lumen or removing the entire system with the guide catheter.

Abstract

An intravascular basket device for use in capturing either naturally occurring or foreign debris found in blood vessels or other regions of the body. The basket device is fabricated from a tube and includes a mid-section having at least one ring configured in an alternating V-pattern. The basket device specifically embodies structure that provides enhanced radial opening and angular resistance to collapse.

Description

    CROSS-REFERENCES TO RELATED APPLICATIONS
  • This application is a continuation-in-part of application Ser. No. 09/469,431, filed Dec. 23, 1999. The content of that application is hereby incorporated herein by reference.
  • BACKGROUND OF THE INVENTION
  • The present invention relates generally to intravascular devices and systems and more particularly, basket devices which can be used to capture embolic material or thrombi found in blood vessels.
  • The intravascular basket device and system of the present invention is particularly useful when performing balloon angioplasty, stenting procedures, laser angioplasty or atherectomy in critical vessels where the release of embolic debris into the bloodstream can occlude the flow of oxygenated blood to the brain or other vital organs, which can cause devastating consequences to the patient. The basket device is also suited for the removal of clots adhering to vessel walls. The device is also suitable for removal of misplaced coils or other foreign material. While the basket device and system of the present invention is particularly useful in the cerebral vasculature and neurovasculature, the invention can be used in conjunction with any vascular interventional procedure in which there is an embolic risk. Additionally, it can be used in any region of the body where removal of debris or foreign material is indicated. Having a patterned body cut from a single tube element, the basket device allows for an enhanced radial opening into the basket body that provides for greater ease of embolic capture. Additionally the patterned body embodies greater stability during use by resisting the natural tendency to collapse as seen in most prior art snares during a typical operation.
  • A variety of non-surgical interventional procedures have been developed over the years for opening stenosed or occluded blood vessels in a patient caused by the build-up of plaque or other substances on the wall of the blood vessel. Such procedures usually involve the remote introduction of the interventional device into the lumen of the artery, usually through a catheter. In typical carotid PTA procedures, a guiding catheter or sheath is percutaneously introduced into the cardiovascular system of a patient through the femoral artery and advanced, for example, through the vasculature until the distal end of the guiding catheter is in the common carotid artery. A guidewire and a dilatation catheter having a balloon on the distal end are introduced through the guiding catheter with the guidewire sliding within the dilatation catheter. The guidewire is first advanced out of the guiding catheter into the patient's carotid vasculature and is directed across the arterial lesion. The dilatation catheter is subsequently advanced over the previously advanced guidewire until the dilatation balloon is properly positioned across the arterial lesion. Once in position across the lesion, the expandable balloon is inflated to a predetermined size with a radiopaque liquid at relatively high pressures to radially compress the atherosclerotic plaque of the lesion against the inside of the artery wall and thereby dilate the lumen of the artery. The balloon is then deflated to a small profile so that the dilatation catheter can be withdrawn from the patient's vasculature and the blood flow resumed through the dilated artery. As should be appreciated by those skilled in the art, while the above-described procedure is typical, it is not the only method used in angioplasty.
  • Another procedure is laser angioplasty which utilizes a laser to ablate the stenosis by super heating and vaporizing the deposited plaque. Atherectomy is yet another method of treating a stenosed blood vessel in which cutting blades are rotated to shave the deposited plaque from the arterial wall. A vacuum catheter is usually used to capture the shaved plaque or thrombus from the blood stream during this procedure.
  • In the procedures of the kind referenced above, abrupt reclosure may occur or restenosis of the artery may develop over time, which may require another angioplasty procedure, a surgical bypass operation, or some other method of repairing or strengthening the area. To reduce the likelihood of the occurrence of abrupt reclosure and to strengthen the area, a physician can implant an intravascular prosthesis for maintaining vascular patency, commonly known as a stent, inside the artery across the lesion. The stent is crimped tightly onto the balloon portion of the catheter and transported in its delivery diameter through the patient's vasculature. At the deployment site, the stent is expanded to a larger diameter, often by inflating the balloon portion of the catheter.
  • Prior art stents typically fall into two general categories of construction. A first type of stent is expandable upon application of a controlled force, as described above, through the inflation of the balloon portion of a dilatation catheter which, upon inflation of the balloon or other expansion means, expands the compressed stent to a larger diameter to be left in place within the artery at the target site. A second type of stent is a self-expanding stent formed from, for example, shape memory metals or super-elastic nickel-titanum (NiTi) alloys, which will automatically expand from a compressed state when the stent is advanced out of the distal end of the delivery catheter into the body lumen. Such stents manufactured from expandable heat sensitive materials allow for phase transformations of the material to occur, resulting in the expansion and contraction of the stent.
  • The above minimally invasive interventional procedures, when successful, avoid the necessity of major surgical operations. However, there is one common problem which can become associated with all of these types of procedures, namely, the potential release of embolic debris into the bloodstream that can occlude distal vasculature and cause significant health problems to the patient. For example, during deployment of a stent, it is possible that the metal struts of the stent can cut into the stenosis and shear off pieces of plaque which become embolic debris that can travel downstream and lodge somewhere in the patient's vascular system. Pieces of plaque material can sometimes dislodge from the stenosis during a balloon angioplasty procedure and become released into the bloodstream. Additionally, while complete vaporization of plaque is the intended goal during a laser angioplasty procedure, quite often particles are not fully vaporized and thus enter the bloodstream. Likewise, not all of the emboli created during an atherectomy procedure may be drawn into the vacuum catheter and, as a result, enter the bloodstream as well.
  • When any of the above-described procedures are performed in the carotid arteries, cerebral vasculature, or neurovasculature, the release of emboli into the circulatory system can be extremely dangerous and sometimes fatal to the patient. Naturally occurring debris can also be highly dangerous to a patient. That is, debris which travels through the blood vessel as a natural result of bodily functions and not as a result of an intervention procedure. Debris that is carried by the bloodstream to distal vessels of the brain can cause these cerebral vessels to occlude, resulting in a stroke, and in some cases, death. Therefore, although cerebral percutaneous transluminal angioplasty has been performed in the past, the number of procedures performed has been limited due to the justifiable fear of causing an embolic stroke should embolic debris enter the bloodstream and block vital downstream blood passages.
  • Medical devices have been developed to attempt to deal with the problem created when debris or fragments that naturally occur or that enter the circulatory system following vessel treatment utilizing any one of the above-identified procedures. One approach which has been attempted is the cutting of any debris into minute sizes which pose little chance of becoming occluded in major vessels within the patient's vasculature. However, it is often difficult to control the size of the fragments which are formed, and the potential risk of vessel occlusion still exists, making such a procedure in the carotid arteries a high-risk proposition.
  • In addition, the retrieval of fragmented clot may be incomplete, also resulting in emboli and distal occlusions, and further, access through tortuous lumens may prove difficult. Laser-based disruption devices employ the photo-acoustic effect to fragment clot. Local disruption may open up a proximal occlusion but also may cause significant distal emboli.
  • Other techniques which have been developed to address the problem of removing embolic debris include the use of catheters with a vacuum source which provides temporary suction to remove embolic debris from the bloodstream. However, as mentioned above, there have been complications with such systems since the vacuum catheter may not always remove all of the embolic material from the bloodstream, and a powerful suction could otherwise cause problems to the patient's vasculature. Other techniques which have had some limited success include the placement of a filter or trap downstream from the treatment site to capture embolic debris before it reaches the smaller blood vessels downstream. However, there have been problems associated with conventional filtering systems as well. In particular, certain previously developed filtering devices do not optimize the area for embolic collection. That is, conventional filtering devices may not present a collection device that spans the entirety of the vessel or it may include supporting structure that itself impedes emboli collection. Certain other devices do not embody sufficient angular resistance to collapse.
  • Moreover, thrombectomy and foreign matter removal devices have been disclosed in the art. However, in addition to suffering from the same disadvantages as certain conventional filter devices, such devices have been found to have structures which are either highly complex such as with multiple components or highly convoluted geometry or lacking in sufficient or effective expansion and retraction capabilities. Disadvantages associated with the devices having highly complex structure such as with multiple components or highly convoluted geometry include difficulty in manufacturability as well as use in conjunction with microcatheters. Other devices with less coverage can pull through clots due in part to the lack of experience in using the same or otherwise lack an expanded profile that is adequate to capture clots or foreign bodies.
  • Furthermore, in current interventional radiology practice, the need arises to remove a variety of objects from intraluminal spaces. Among these are embolic coils, guidewire tips, distal catheter segments, thrombus and other vascular emboli, few of which can be readily removed with current devices.
  • Thrombo-embolic materials can be friable, amorphous, and/or lubricious in nature contributing to this difficulty. Most current therapies rely on grasping, fragmenting, or dissolving the blood-based obstructions. Among the grasping devices are the loop snares and the wire basket snares. These devices may have limited effectiveness, due in part to the lack of encapsulation. Objects are difficult to grasp within these devices, and friable objects, e.g. blood-based blockages, tend to fragment when grasped or pulled, introducing multiple emboli.
  • Lytic drugs are also used to dissolve blood-based obstructions. These typically have the disadvantages of lengthy treatment/infusion times to remove the obstruction (>3 hrs.), production of emboli, and the potential for systemic iatrogenic bleeding as a side effect of the drug usage. Also, these drugs are not typically effective in removing obstructions that are not blood-based.
  • What has been needed is a reliable intravascular basket device and system for use when treating blood vessels. The basket devices should be capable of capturing any naturally occurring embolic debris or that which may be released into the bloodstream during an interventional treatment, while minimizing profile during delivery and maximizing coverage when deployed to safely contain the debris until the basket device is removed from the patient's vasculature. The devices should embody an expanded profile that presents a consistent radial opening that completely occupies the vessel at the repair site as well as structure for effectively resisting collapse. Moreover, such devices should be relatively easy to deploy and remove from the patient's vasculature and also should be capable of being used in narrow and very distal vasculature such as the cerebral vasculature. The following invention addresses these needs.
  • SUMMARY OF THE INVENTION
  • Briefly and in general terms, the present invention is directed towards a basket for removing undesired material or objects and restoring patency of blood vessels. The basket is a linked or monolithic framework of thin struts that is radially expansible. The basket of the present invention embodies a structure that provides a consistent radial opening as well as improved radial and angular resistance to collapse. That is, as the device is pulled such as through a vessel, the entrance thereto will not fall back or tip over. Moreover, the basket device maintains clearance in its interior space along its length allowing the material or objects to enter and be captured.
  • In one aspect of the invention, the basket includes struts with very small widths and thicknesses and rings with very small widths and thicknesses but large expansion ratios. It is particularly beneficial to manufacture the basket from a piece of tube stock, as opposed to prior art wire baskets, because the resulting basket is more ordered upon compression, returns to its expanded state more reliably and is quicker to manufacture. The body of the basket device is defined by a plurality of openings bounded by generally longitudinally and generally circumferentially extending members. A proximally extending member is attached to an elongate wire and the assembly is contemplated to be used in conjunction with a generally tubular delivery catheter. In this aspect the body provides enhanced stability at the proximal transition between the wire and the proximally extending members because the design may allow for varying lengths and widths of the proximally extending members. The basket may be manufactured from a single tubular element or from a sheet to form a desired configuration.
  • Overall, the intent of the invention is to provide a structure that has the capacity to engage, encompass and retain naturally occurring or foreign bodies while having a minimal profile that can traverse easily and repeatedly through a standard microcatheter across tortuous anatomy. The device embodies superior flexibility to be deployed and retrieved consistently across difficult anatomy while being able to retain captured material. The inner diameter of the device is heat-set to a pre-determined size. It is envisioned that there be a family of devices that have varying strut lengths, thicknesses, flexibility, and diameters as deemed appropriate for the specific type of vascular or non-vascular setting for which the device is to be used.
  • In a presently preferred embodiment, the basket device is self-expanding and includes a mid-section that forms a generally tubular profile. The proximally extending member projects as an axial extension of a line at the surface of the cylinder generally defining the substantially tubular portion to thereby provide an unobstructed opening at the proximal end of the basket. A terminal (i.e., distal) end of the basket device can be closed or constricted so as to form a pocket for receiving emboli or thrombotic debris.
  • The basket device can assume a number of forms. In one presently contemplated aspect, the basket device of the present invention embodies first and second end portions, and a mid-section having a plurality of consecutive rings, each ring having a plurality of generally straight members configured in an alternating V-pattern providing a plurality of proximal and distal apices. In another aspect, the intravascular basket device has a mid-section defined by a single ring also having generally straight members configured in an alternating V-pattern providing four apices on each of the mid-section proximal and distal ends. In yet another embodiment, the mid-section may embody a double ring design configured in a four apex pattern. In other aspects, the basket device mid-section may include rings having different lengths or, in the alternative, include a proximal section having different lengths. In the embodiments, the plurality of members can be curved, S-shaped, angled, tapered etc. rather than straight or can be a combination of straight and curved, angled, tapered or other combinations etc.
  • Moreover, the present invention embodies a tip for an endovascular device including an atraumatic soft coil for preventing damage to tissue and facilitates advanceability. The tip further includes multiple layers of coiled material to enhance these objectives as well as to provide stiffness variations.
  • These and other objects and advantages of the invention will become apparent from the following more detailed description, when taken in conjunction with the accompanying drawings of illustrative embodiments.
  • BRIEF DESCRIPTION OF THE DRAWINGS
  • FIG. 1 is a side view, partially in cross-section, of a vessel occluded by debris and a distal portion of a delivery catheter and intravascular snare assembly of the present invention positioned proximate the debris;
  • FIG. 2 is a side view, partially in cross-section, of the intravascular basket as deployed within the vessel of FIG. 1;
  • FIG. 3 is a plan view, depicting a pattern of a preferred embodiment of an intravascular basket of the present invention as if the basket was cut longitudinally and unrolled to show its pattern in a flat configuration;
  • FIG. 3 a is an enlarged view of a portion of an intravascular basket of the present invention, depicting curvilinear members defining the basket;
  • FIG. 3 b is an enlarged view of a portion of an intravascular basket of the present invention, depicting a filler member positioned between other members defining the basket;
  • FIG. 4 is a plan view, depicting an unrolled pattern of a second alternative embodiment of an intravascular basket of the present invention;
  • FIG. 5 is a plan view, depicting an unrolled pattern of a third alternative embodiment of an intravascular basket of the present invention;
  • FIG. 6 is a plan view, depicting an unrolled pattern of a fourth alternative embodiment of an intravascular basket of the present invention;
  • FIG. 7 is a plan view, depicting an unrolled pattern of a fifth alternative embodiment of an intravascular basket of the present invention;
  • FIG. 8 is a plan view, depicting an elongate member of the present invention;
  • FIG. 9 is a side view, partially in cross-section, depicting a plurality of coils configured about a distal end portion of the elongate members in combination with a basket device of the present invention;
  • FIG. 10 is a cross-sectional view, depicting the assembly of FIG. 9 taken along lines 10-10;
  • FIG. 11 is a side view, partially in cross-section, depicting a distal end portion of a tip of the basket device of the present invention;
  • FIG. 12 is a cross-sectional view, depicting a portion of the assembly of FIG. 11 taken along lines 12-12;
  • FIG. 13 is a cross-sectional view, depicting the assembly of FIG. 11 taken along lines 13-13;
  • FIG. 14 is a perspective side view, depicting the device pattern projected onto the tubing which it will be cut from to produce the basket device of FIG. 3; and
  • FIG. 15 is a perspective bottom view, depicting the device pattern projected onto the tubing which it will be cut from to produce the basket device of FIG. 3.
  • DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS
  • Referring now to the drawings, and in particular FIGS. 1 and 2, there is shown a basket device of the present invention. The basket device 20 is adapted to provide more consistent and improved radial opening as well as enhanced angular resistance to collapse. Moreover, the basket device 20 of the present invention is configured to facilitate the maintenance of clearance in its interior space along its length allowing the material or objects to enter and be captured. Furthermore, since it is contemplated that the basket device 20 be manufactured from a tubular member to form elements with very small widths and thicknesses, the device is thus more easily packed to a relatively smaller diameter and inherently embodies high longitudinal flexibility.
  • The basket device 20 (FIG. 2) of the present invention includes a body 22 having a proximal end portion 24 and a distal end portion 26. The proximal end portion 24 is intended to be affixed to a terminal end portion of an elongate member 30 (i.e., wire; described in more detail below). In a presently preferred embodiment, the body 22 of the basket device 20 is generally tubular with a proximally directed opening 32 and a generally closed terminal end 34 to thereby form a basket for receiving embolus, stones, thrombus and foreign bodies found in vasculature or other body cavities.
  • The basket device 20 for intravascular uses is contemplated to be used in conjunction with a generally tubular delivery catheter 40, such as a microcatheter. Additionally, it is contemplated that a conventional guide catheter (not shown) be used in combination with the delivery catheter 40 loaded with a basket device 20. A guide catheter (not shown) is employed to provide a guide within a patient's vasculature through which the delivery catheter 40 is inserted. A proximal end of the guide may include a rotating hemostatic valve or “Y” adapter fitted with sealing hemostatic valves. The basket device 20 is intended to be self-expandable, however, it is possible to employ an expandable member such as a balloon catheter (not shown) to radially expand the basket device that is not self-expandable, but rather must be deformed to assume an expanded configuration.
  • In use, the body 22 of the basket device 20 is placed proximally in a compressed configuration coaxially within an internal bore of the generally tubular delivery catheter 40. The longitudinally extending elongate member 30 which is attached to the proximal end 24 of the body 22, is likewise coaxially received within the delivery catheter 40. Both the body 22 and elongate member 30 are slidable within the delivery catheter 40 and accordingly, the delivery catheter 40 and the basket device 20 can be displaced longitudinally with respect to each other.
  • A typical procedure will now be described. In order to restore patency in a vessel, the basket device/delivery catheter assembly 42 is introduced into a patient's vasculature using conventional means such as the Seldinger technique. Sometimes, a cutdown is made to gain access to the patient's vasculature. Using standard endovascular techniques, the emboli in the vasculature is located. The emboli is crossed with an appropriate guidewire (not shown) then the delivery catheter 40. If the vessel is occluded, contrast is injected distal to the occlusion to map the distal vessels. The tip 48 of the delivery catheter 40 is positioned one basket length or slightly more beyond the emboli. The guidewire is removed and the basket device 20 is loaded through a rear hub (not shown) of the delivery catheter 20 with the assistance of an introducer sheath (not shown). The basket device 20 is advanced 30-40 cm and the introducer sheath is then removed.
  • Next, the basket device 20 is advanced until the tip 26 of the basket is positioned at the distal end of the delivery catheter 40. Radioopaque markers are located on either side of the basket so that the operator can see when the basket is located just inside of the end of the delivery catheter 40. The basket device 20 is held in place by the operator holding the elongate member 30 still while the catheter 40 is retracted to allow the basket device to expand. Holding the basket device 20 in place, the catheter 40 is pulled back until it is proximal to the emboli 46. Then, the basket device is drawn back allowing the emboli 46 to enter the basket device 20. Alternatively, the entire system can be drawn back holding relative positions between the basket device 20 and the catheter 40. This step can be assisted with a “stuttering” technique where the basket device 20 is drawn out a small amount, perhaps 2 mm, then the elongate member 30 is advanced back perhaps 1 mm to allow the mouth of the basket device 20 to re-open fully, thereby assisting clot or emboli entry into the basket. Then the system is drawn out another 1 mm. This is repeated until the basket device 20 has traversed a distance about its own length. To reduce the risk of losing the material contained in the basket or device, blood flow control may be used during extraction. For example, a guiding catheter with a flow control device such as an elastomeric balloon at the distal tip may be employed to slow or stop blood flow past the device during retrieval.
  • If the emboli 46 is foreign in origin, such as a coil, the basket device 20 can be moved back and forth past the coil in an iterative attempt to engage the coil in the struts of the basket. When this has occurred, the catheter 40 can be advanced causing the basket to collapse and pinch the coil, locking it into one of the openings of the basket device 20. If the emboli is not radiopaque, its position may be checked by a contrast injection and noting a “filling defect.” Also, the radiopaque tip 26 of basket device 20 can be observed under fluoroscopy during this process. A pulsing motion can indicate restored flow.
  • The system 42 is then drawn back until the distal end of a proximal device marker coil (described below) is at the tip of the guide. At this point, a large syringe, perhaps 60 cc, is attached to the guide catheter at the “Y” adapter on the hub. The guide catheter is aspirated as the basket device 20 and emboli 46 are drawn into the guide. Aspiration is maintained until the basket device 20 is fully into the “Y” adapter of the guide catheter, but the basket device 20 is not yet drawn through the hemostatic valve. The “Y” adapter is detached and removed with the basket device in it, allowing a moment of bleed back through the guide to flush any loose emboli. Optionally, then a second “Y” arm is attached to prevent excessive bleed back. The guide is then flushed with saline and the entire procedure repeated as required to remove further emboli.
  • The manner in which the body portion 22 of the basket device 20 self-expands within the vasculature and the resultant expansion profile provides a number of advantages. In particular, the body 22 expands to conform to the repair site 44. That is, the generally tubular profile of the body portion 22 substantially conforms to the walls defining the blood vessel 49. Alternatively, the basket device 20 can be sized such that upon full expansion it has a diameter smaller than the diameter of the blood vessel 49 if desired. Moreover, the expansion of the body 22 facilitates the maintenance of clearance in its interior space along its length allowing the material or objects 46 to enter and be captured and specifically provides a substantially unobstructed access to the proximally directed opening 32 to the body 22. Significantly, as the body 22 self-expands, members 50 and 51 leading to the opening 32 to the body 22 are angled or oriented so as to be adjacent to the walls defining the blood vessel 49 and are therefore substantially removed from the flow path to thereby provide an unobstructed opening 32.
  • In its expanded state, the basket device 20 is particularly well-suited to remove embolic or thrombotic debris 46 from the blood vessel 49. As stated, the basket device 20 can be withdrawn proximally so that the debris 46 can be captured by the body 22 of the basket device 20. Alternatively, a separate pusher mechanism (not shown) can be employed to push the debris 46 within the basket defined by the body portion 22. Once the debris has been captured, the system 42 can be removed from the patient's vasculature or the basket device 20 containing the debris 46 can first be pulled within the guide catheter (not shown) and then the assembly 42 removed from the target repair site 44. Also, just the proximal end portion 24 of the basket device 20 can be cinched down to lock the debris without being fully pulled into the delivery catheter 40.
  • It is to be understood, however, that thrombus or other blood-based material captured within the basket may be eliminated in a variety of ways. For example, the material may be drawn into the guide catheter with the aide of suction applied to the guide catheter, and removed from the body. Also, these materials may be removed from the occluded vessel and allowed to dissolve under natural or induced lytic processes. Alternately, the blood-based material may be inserted into other vasculature more tolerant of occlusion and released.
  • Referring to FIG. 3, in a preferred embodiment of a basket pattern 125 shown as if it was cut longitudinally and unrolled to depict its pattern in a flat configuration, a basket 20 includes a proximal section 126, mid-section 132, and a distal section 127. The sections 126, 132 and 127 together form a substantially tubular basket body 22 with a tapered distal end as will be developed further below. It is contemplated that the body 22 embodying such a pattern 125 be cut from a tubular member using a laser. Alternatively, the body can be made from a flat sheet of nitinol and rolled into a tubular basket body. As best seen in its flattened or unrolled state, the basket pattern 125 further includes an elongate member 30 extending proximally from a proximal end portion 53 of the basket body 22. It is also to be recognized that each of the members defining the basket body 22 in this or other embodiments may have curved, arced, S-shaped, partially straight sections or other configurations (See FIG. 3 a, for eg.). Additionally, it is contemplated that the body can further include branches 121 with an enlarged or angled terminal end (FIG. 3 b) which act as fillers between other members defining the body 20. Such fillers 121 aid in providing a basket highly equipped to contain material.
  • The proximal section 126 of the basket 20 includes a proximal end 23, a distal end 25 and a straight member section 128. The straight member section 128 includes a plurality of members 130 generally configured in a V-shape in that the members “fan out” or diverge in a distal direction. In this configuration, the straight members 130 lead to and aid in defining an opening 32 (see FIGS. 2 and 14) to the body 22, when in its as-cut tubular configuration. Therefore, the members 130 of the straight member section 128 are pair-wise configured in a V-shape such that two proximal vertices 129 are formed where the members 130 proximally merge and four open-ended distal end points 131 are provided to define the distal end 25 of the member section 128. It is noted that in the current configuration, the straight member section 128 defines the entirety of the basket proximal section 126, however, as will be subsequently discussed, in alternative embodiments, the proximal section 126 may include a plurality of straight member sections. Finally, the two proximal vertices 129 of the member section 128 merge into two curved members 50. The curved members 50 converge proximally to form a tab 53 that may be connected to an elongate member 30.
  • The mid-section 132 of the basket pattern 125 may be of a four apex design including a single ring 133 that defines the generally tubular mid-section 132. The ring 133 includes a plurality of straight members 136 configured in an alternating V-pattern forming a plurality of proximal apices 135 and distal apices 137. In order to achieve the four apex design of basket pattern 125, the ring 133 of the basket mid-section 132 may include eight straight members 136 converging end to end in an alternating V-pattern to form four proximal apices 135 and four distal apices 137. Each of the four proximal apices 135 merge into the open-ended distal end points 131 of the straight members 130 of the basket proximal section 126.
  • The intersection of the four straight members 130 of the basket proximal section 126 and the straight members 133 of the basket mid-section 132 at the proximal apices 135 define a plurality of diamond-shaped apertures 118. Additionally, a single enlarged diamond-like aperture 116, located substantially within the basket proximal section 126, is defined by the intersections at the proximal end of the basket proximal section 126 between the two curved members 50 and the proximal vertices 129 of the basket proximal section 126 and the intersections at distal end of the basket proximal section between the distal end points 131 of the proximal section 126 to the proximal apices 135 of the basket mid-section 132.
  • Referring still to FIG. 3, the distal section 127 of the basket 20 includes a single straight member section 139 having straight members 140 in a V-shape configuration that “fans-in” (i.e., converge) distally. At the proximal end, the straight members 140 include four open-ended proximal ends 138 (the branches of the V-shape) at the distal apices 137 of the basket 20 mid-section 132. At the distal end, straight members converge to form two vertices 141 at the distally directed members 142. The junction between the two straight members 140 of the basket distal section 127 and the straight members 133 of the basket mid-section 132 at the distal apices 137 define a plurality of diamond-shaped apertures 120.
  • The distally directed straight members 142 of the basket distal portion 127 may be joined together to form a substantially closed basket. This structure can be joined using soldering or by employing a coil (described herein below) that is wrapped about adjacent structures to form a soft tip. The distally directed extensions 142 may also be trimmed to a desired length.
  • Another way to describe the basket device is that it begins with a proximal elongate member linked to a series of divergent branches of increasing density covering successively smaller fractions of the tubular circumference. The increasing density of the divergent branches wrap around the circumference from the side where the elongate member ends to form the tube. Linked from the divergent branches is one or more ring segments in which an equal number of struts enter and exit at the joints. Branching from the ring segment is a series of convergent branches of decreasing density covering successively larger fractions of the tubular circumference. This section is tapered down to the distal tip to reduce the required coverage area thus maintaining adequately small openings for encapsulation.
  • It is noted that the dimensions of a basket pattern may be varied in a number of ways to produce a number of alternative embodiments of the current invention. From these alternative embodiments it will be understood that the lengths of the straight members of the mid-section rings may be varied accordingly to address any specific application requirement. Similarly, the lengths of the generally straight members of the member section of the proximal section may also be varied in length according to the desired design requirement. In order to have the device collapse evenly, all continuous (not recursive) paths from the first bifurcation to the last convergence of members must be of approximately the same length. Otherwise, during collapse the longer members are forced to buckle or the shorter members are forced to stretch to achieve a substantially linear constrained configuration.
  • Referring to FIGS. 4-7, alternative embodiments of the current invention are depicted. Generally, the basket patterns 145 include a mid-section 148 having two rings 152 and 153 configured in a “four apex” design. Each ring 152, 153 is defined by a plurality of connected vees to thereby define a ring having a generally serpentine pattern. A two ring design having a distal taper may provide enhanced clot capturing capabilities because of the smaller sized apertures located at the distal portions of the basket body 22. In the second and fourth embodiments (FIGS. 4 and 6), the rings 152 and 153 include straight members 155 and 159 having a first length. In the third and fifth embodiments (FIGS. 5 and 7), the rings 152 and 153 include straight members 170 and 174 having a second length that is longer than the first length of straight members 155 and 159. Therefore, the rings 152 and 153 of the second and fourth embodiments are shorter in length than the rings 152 and 153 of the third and fifth embodiments. It is envisioned that the length of the rings of the third and fifth embodiments may be two or more times longer than the rings of the second and fourth embodiments and that there can be any number of rings.
  • As with the previous embodiment described above, in all four alternative embodiments of basket pattern 145 (FIGS. 4-7), the straight members of each ring are configured in an alternating V-pattern layout to produce four apices on both the proximal and distal ends of each ring. Each ring 152 includes proximal apices 154 and distal apices 156 and each ring 153 includes proximal apices 158 and distal apices 160. The ring 152 is connected to ring 153 at the connection 157 between apices 156 and 158. Together rings 152 and 153 form the generally tubular mid-section 148.
  • Similar to the first embodiment (as shown in FIG. 3), the basket patterns 145 of the second through fifth embodiments (FIGS. 4-7) includes a proximal section 146 and a distal section 147 configured and connected to the mid-section 148 in a like manner as the first embodiment. As mentioned above, the two ring design of the basket patterns 145 allow for a distally tapering body 22 that provides for the capture of smaller emboli because the additional ring results in a body 22 having an increased number of apertures which are each smaller in size than those of the single ring design.
  • Referring to FIGS. 6 and 7, further variations on the embodiments of FIGS. 4 and 5 respectively are provided. The variations include changes to the proximal transition defining proximal opening 32 of the basket 20. Therefore, in the second and third embodiments (FIGS. 4 and 5), a first member section 150 includes straight members 151 having a first length, while in the fourth and fifth embodiments (FIGS. 6 and 7) the first member section 150 includes straight members 181 having a second length that is shorter than the length of straight members 151. The change in the length of the members of the first member section 150 is intended to increase the radial strength of the device proximally. Therefore, the radial strength of the proximal transition of the device body 22 is increased which improves emboli capture by holding the device open and a shorter tab improves push by providing greater resistance to column buckling.
  • As can be seen from the various embodiments presented herein, the basket device 20 may be configured having different mid-section 148 or proximal section 146 lengths or may be designed to include different numbers of apices within the mid-section. These changes are only dependent on the design requirements of the physician, and any such modification will not depart from the scope of the present invention.
  • Referring now to FIG. 8, there is shown one preferred embodiment of the elongated member 30 of the present invention. The member 30 embodies a gradual or step-tapered core comprising a proximal section of 304V stainless steel and a distal section of nitinol or an equivalent material for the intended purpose. A proximal portion 200 of the member 30 has a generally constant cross-sectional profile and a first diameter 201. At a transition point 202, the member 30 begins to taper in a gradual and consistent, alternatively in a step-tapered or in parabolic or other non-linear manner, from the first diameter 201 to a second diameter 203 along a distal end portion 204.
  • As shown in FIGS. 9 and 10, a pair of longitudinally adjacent arranged coils 206, 208 are employed to attach a proximal tab 214 of a basket device 20 to the distal end portion 204 of the elongate member 30. The first, proximal coil 206 is contemplated to be composed of 304V stainless steel, the first coil being soldered to the elongate wire 30 near its tapered portion 210. The second coil 208 is contemplated to embody a medical grade radiopaque wire, typically a platinum alloy such as about 90% platinum and 10% iridium alloy. This second coil 208, which serves as a radiopaque marker, is soldered to the elongate member 30 near a distal end portion 212 of the first coil 206. Alternatively, the second coil 208 is soldered to the first coil 206. A proximal tab 214 of the basket device 20 is contained within the second coil 208 and is soldered 216 to the elongate member 30.
  • Turning now to FIGS. 11-13, one presently preferred embodiment of a distal tip portion 220 of the basket device 20 of the present invention is described. The distal tip portion 220 embodies two partially coaxial coils 222, 224, the combination of which retains the distally directed extensions projecting from the body 22 of the basket device 20. The combination also provides a soft atraumatic tip with variable stiffness from softest distally to stiffer proximally. Varying the relative lengths of the tip and coils 222, 224 results in creating changes in stiffness and thus, can be selected to provide the device with desired flexibility.
  • The inner coil 222 is comprised of nitinol or equivalent material, and begins at a proximal location 226 and extends to a distal location 228. The nitinol inner coil 222 provides kink resistance as well as creates a smooth stiffness transition from the tip of the basket portion of the basket device 20. The outer coil 224 is coaxially configured about a distal portion 230 of the inner coil 222 and is preferably comprised of 90% platinum and 10% iridium alloy or an equivalent combination of materials. As such, the outer coil 224 can operate as a radiopaque marker.
  • The distal tip portion 220 further includes a rounded terminal end 232 that provides a blunt atraumatic surface. The terminal end 232 embodies a soldered joint which acts in retaining the helical configuration of the outer coil 224.
  • With reference to FIGS. 14 and 15, a brief summary of the process used to manufacture the basket devices 20 of the present invention is provided, with a specific focus on a second embodiment of the present invention. As shown in FIG. 3, the preferred embodiment of the present invention is relatively similar to the other embodiments disclosed and includes a four apex single ring pattern 125. It is contemplated that the basket devices 20 of the present invention be cut from a tube 240 using a laser. In particular, a specific pattern is programmed into the laser device and the laser is activated to cut the desired pattern into the tubular element 240. The excess tubular components are removed, thereby leaving a manufactured structure such as the basket pattern 125 shown in FIG. 3, corresponding to the desired pattern. In a presently preferred embodiment, a superelastic material such as nitinol is a material of choice for the basket device 20. Thereafter, post-processing such as surface treatment, burr removal, oxide removal and/or shape setting of the manufactured structure is performed. Heat treating is also performed for stress-relief of the device.
  • In particular, post-processing steps include taking an as-cut device and bead blasting the device with aluminum oxide blasting media. The device is then inspected under a microscope for residual slag. If slag remains, the device is bead blasted again. Thereafter, the device is stress relieved in a molten salt bath without expanding. The device is subsequently heat-expanded in a molten salt bath mounted on a suitable size mandrel. After heat expansion, surface oxidation is removed in an aqua regia bath. When nitinol is the material of choice, the nitinol is etched with HF solution to desired strut size resulting in desired softness. The device is then mounted on a guidewire using coils and solder.
  • In the case of the pattern 125, the post-processing may include deforming the pattern 125 and then joining together the distal end members 142 for the purpose of achieving a closed basket for receiving debris found in vasculature. Being so configured, the pair of diverging members 50 define an opening 32 to the resultant basket and the elongate member 30 extends from a sidewall defined by the opening.
  • The basket devices of the present invention each provide improved radial opening compared to prior art loop snares since in an expanded state, the elongate member 30 is positioned substantially out of the flow path. Additionally, the device embodies improved resistance to radial and axial loads compared to prior art loop snares. Moreover, since less deformation is required to produce a desired basket pattern, in that, angles between members are provided by laser cutting rather than from local deformations, for example, there is potentially improved stress distribution along the basket devices of the present invention compared to prior art loop snares. Additionally, a greater reduction in radial profile can be achieved without sacrificing performance and in particular, the device can be used in conjunction with microcatheters. As such, the basket devices 20 of the present invention can be passed through narrow and tortuous vasculature. The applications of the present invention are more widespread than that of conventional snare devices because of greater retrieval characteristics while retaining the deliverability characteristics.
  • The above described invention is principally conceived to be operational for use in engaging for the purpose of displacing and/or removing material either foreign or native to the body, including partial or complete obstructions embolic and/or thrombotic in nature, from intraluminal or extraluminal spaces of the body including but not limited to intravascular and/or intra-arterial regions of the cerebral vasculature, as well as tubings, stents, or other objects that may or may not be internal to the body. The purpose of the device is to restore functionality of the luminal space or systems dependent on the particular luminal space or as a method of producing any desired effect associated with the removal or displacement of undesirable material.
  • The intended delivery of the disclosed invention is by means of a commercially available catheter selected for its ability to access the desired location of engagement. The invention may be optimized for specific locations or uses by means of sizing the individual elements in the design and/or the overall dimensions, as well as selection of materials, mesh configuration, number and relative geometry of component members to meet the requirements of the operational space. Optimizations may include tabs protruding from the sides of members to increase coverage of the open areas between members, offsetting vertices of joints to increase packing efficiency, or providing unconnected distal curved path. There may additionally be variations of the dimensions of length, thickness, and width of distal and proximal tabs for joining basket with delivery wire and distal tip to provide smooth stiffness transitions from tip to basket and basket to delivery wire. Such optimizations are means of adjusting operational attributes including: flexibility, applied circumferential force, engagement effectiveness, deliverability and traversal through tortuous vasculature, and volume of material to be engaged.
  • Alternate or additional materials for the basket portion of the device may include a shape memory polymer thermoset, elastomer, thermoplastic constituents such as nylon, or other metal either pure or alloyed, as well as composite materials such as a combination of glass, aramid, or carbon in a binding matrix. A secondary mesh of the same or dissimilar material may be added to the basket. The wire portion of the device can alternatively be made from a single metal or combination of metals for kink resistance and high flexibility. Either or both components may be tapered to give a transition in stiffness that is appropriate for the vessel in which the invention is to be delivered. The distal tip of the device may incorporate concentric coils made of nitinol, stainless steel, or other metal or plastic to provide a soft flexible atraumatic end.
  • An alternate method of manufacture of the basket portion of the device may be photo etching, or metal or polymer injection molding or water jet cutting. Furthermore, the device may employ any combination of coatings, agents, or features including those that result from material addition or subtraction to create grooves, bumps, three dimensional patterns, and textures on inner and/or outer surfaces or any combination thereof to promote desired properties such as adherence of materials to be engaged, radiopacity, and low friction between the device and the vessel wall or microcatheter lumen.
  • In summary, the invention is deliverable to remote regions of the vasculature by gaining access through the use of a guidewire and microcatheter in the vasculature and subsequent deployment of the invention through the lumen of the microcatheter. In a vessel in which flow is impeded or obstructed by material and/or objects including those formed by the body such as blood clot, the device is deployed by withdrawing the microcatheter relative to the elongate wire and basket. Engagement occurs as the system composed of the invention is pulled proximal, causing the basket to encompass the material. After the material has been engaged, removal of the material is accomplished by withdrawing the system into a guide catheter lumen through which the microcatheter is passed with or without simultaneously pulling fluid through the guide lumen or removing the entire system with the guide catheter.
  • Thus, it will be apparent from the foregoing that, while particular forms of the invention have been illustrated and described, various modifications can be made without the parting from the spirit and scope of the invention. Accordingly, it is not intended that the invention be limited, except as by the appended claims.

Claims (19)

1-37. (canceled)
38. A medical device for treating vasculature of a patient, comprising:
an elongate member, the elongate member having a first end portion and a second end portion and including a portion which tapers from a first transverse dimension to a second transverse dimension; and
a filter body, the filter body attached to the second end portion of the elongate member.
39. The device of claim 38, wherein the elongate member tapers in a direction from the first end portion to the second end portion.
40. The device of claim 38, wherein the elongate member includes a tapered portion, the tapered portion characterized by a gradual taper.
41. The device of claim 38, wherein the elongate member includes a tapered portion, the tapered portion characterized by a step-taper.
42. The device of claim 38, wherein the elongate member includes a tapered portion, the tapered portion characterized by a non-linear taper.
43. The device of claim 38, wherein the elongate member includes a tapered portion, the tapered portion characterized by a parabolic taper.
44. The device of claim 38, wherein the filter body includes a tab.
45. The device of claim 44, further comprising a coil attaching the tab to the elongate member.
46. The device of claim 44, further comprising a first coil and a second coil each attaching the tab to the elongate member.
47. The device of claim 46, wherein the first coil is formed from 304V stainless steel.
48. The device of claim 47, when the second coil is formed from a platinum alloy.
49. The device of claim 48, wherein the first and second coils are positioned longitudinally adjacent each other.
50. The device of claim 38, wherein the filter body includes a distal tip portion.
51. The device of claim 50, wherein the distal tip portion includes an inner coil and an outer coil.
52. The device of claim 51, wherein the inner and outer coils are coaxially arranged.
53. The device of claim 52, wherein the inner coil is formed from nitinol and the outer coil is formed from a platinum alloy.
54. The device of claim 53, wherein the inner and outer coils have different longitudinal dimensions.
55. The device of claim 52, wherein the distal tip portion includes a rounded terminal end formed from a soldered joint.
US11/317,930 1999-12-23 2005-12-22 Embolic basket Abandoned US20060100663A1 (en)

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US09/469,431 US6402771B1 (en) 1999-12-23 1999-12-23 Snare
US09/939,205 US6575997B1 (en) 1999-12-23 2001-08-24 Embolic basket
US10/423,300 US7004956B2 (en) 1999-12-23 2003-04-25 Embolic basket
US11/317,930 US20060100663A1 (en) 1999-12-23 2005-12-22 Embolic basket

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Cited By (58)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030120303A1 (en) * 2001-12-21 2003-06-26 Boyle William J. Flexible and conformable embolic filtering devices
US20050075663A1 (en) * 2001-11-27 2005-04-07 Boyle William J. Offset proximal cage for embolic filtering devices
US20090019073A1 (en) * 2001-08-29 2009-01-15 Takahi Itoh System and method for transcoding digital content
US20100022951A1 (en) * 2008-05-19 2010-01-28 Luce, Forward, Hamilton 7 Scripps, Llp Detachable hub/luer device and processes
US7662166B2 (en) 2000-12-19 2010-02-16 Advanced Cardiocascular Systems, Inc. Sheathless embolic protection system
US7678131B2 (en) 2002-10-31 2010-03-16 Advanced Cardiovascular Systems, Inc. Single-wire expandable cages for embolic filtering devices
US7678129B1 (en) 2004-03-19 2010-03-16 Advanced Cardiovascular Systems, Inc. Locking component for an embolic filter assembly
US7780694B2 (en) 1999-12-23 2010-08-24 Advanced Cardiovascular Systems, Inc. Intravascular device and system
US7815660B2 (en) 2002-09-30 2010-10-19 Advanced Cardivascular Systems, Inc. Guide wire with embolic filtering attachment
US7842064B2 (en) 2001-08-31 2010-11-30 Advanced Cardiovascular Systems, Inc. Hinged short cage for an embolic protection device
US7867273B2 (en) 2007-06-27 2011-01-11 Abbott Laboratories Endoprostheses for peripheral arteries and other body vessels
US7892251B1 (en) 2003-11-12 2011-02-22 Advanced Cardiovascular Systems, Inc. Component for delivering and locking a medical device to a guide wire
US7918820B2 (en) 1999-12-30 2011-04-05 Advanced Cardiovascular Systems, Inc. Device for, and method of, blocking emboli in vessels such as blood arteries
US7959646B2 (en) 2001-06-29 2011-06-14 Abbott Cardiovascular Systems Inc. Filter device for embolic protection systems
US7959647B2 (en) 2001-08-30 2011-06-14 Abbott Cardiovascular Systems Inc. Self furling umbrella frame for carotid filter
US7976560B2 (en) 2002-09-30 2011-07-12 Abbott Cardiovascular Systems Inc. Embolic filtering devices
US20110184454A1 (en) * 2010-01-27 2011-07-28 Penumbra, Inc. Embolic implants
US8016854B2 (en) 2001-06-29 2011-09-13 Abbott Cardiovascular Systems Inc. Variable thickness embolic filtering devices and methods of manufacturing the same
US8066757B2 (en) 2007-10-17 2011-11-29 Mindframe, Inc. Blood flow restoration and thrombus management methods
US8088140B2 (en) 2008-05-19 2012-01-03 Mindframe, Inc. Blood flow restorative and embolus removal methods
US8137377B2 (en) 1999-12-23 2012-03-20 Abbott Laboratories Embolic basket
US8142442B2 (en) 1999-12-23 2012-03-27 Abbott Laboratories Snare
US8177791B2 (en) 2000-07-13 2012-05-15 Abbott Cardiovascular Systems Inc. Embolic protection guide wire
US20120123466A1 (en) * 2010-11-12 2012-05-17 Stryker Nv Operations, Ltd. Axially variable radial pressure cages for clot capture
US8216209B2 (en) 2007-05-31 2012-07-10 Abbott Cardiovascular Systems Inc. Method and apparatus for delivering an agent to a kidney
US8262689B2 (en) 2001-09-28 2012-09-11 Advanced Cardiovascular Systems, Inc. Embolic filtering devices
US8545514B2 (en) 2008-04-11 2013-10-01 Covidien Lp Monorail neuro-microcatheter for delivery of medical devices to treat stroke, processes and products thereby
US8585713B2 (en) 2007-10-17 2013-11-19 Covidien Lp Expandable tip assembly for thrombus management
US8591540B2 (en) 2003-02-27 2013-11-26 Abbott Cardiovascular Systems Inc. Embolic filtering devices
US8679142B2 (en) 2008-02-22 2014-03-25 Covidien Lp Methods and apparatus for flow restoration
US8845583B2 (en) 1999-12-30 2014-09-30 Abbott Cardiovascular Systems Inc. Embolic protection devices
US8926680B2 (en) 2007-11-12 2015-01-06 Covidien Lp Aneurysm neck bridging processes with revascularization systems methods and products thereby
US8961551B2 (en) 2006-12-22 2015-02-24 The Spectranetics Corporation Retractable separating systems and methods
US9028520B2 (en) 2006-12-22 2015-05-12 The Spectranetics Corporation Tissue separating systems and methods
US9198687B2 (en) 2007-10-17 2015-12-01 Covidien Lp Acute stroke revascularization/recanalization systems processes and products thereby
US9220522B2 (en) 2007-10-17 2015-12-29 Covidien Lp Embolus removal systems with baskets
US9259305B2 (en) 2005-03-31 2016-02-16 Abbott Cardiovascular Systems Inc. Guide wire locking mechanism for rapid exchange and other catheter systems
US9283040B2 (en) 2013-03-13 2016-03-15 The Spectranetics Corporation Device and method of ablative cutting with helical tip
US9291663B2 (en) 2013-03-13 2016-03-22 The Spectranetics Corporation Alarm for lead insulation abnormality
US9413896B2 (en) 2012-09-14 2016-08-09 The Spectranetics Corporation Tissue slitting methods and systems
USD765243S1 (en) 2015-02-20 2016-08-30 The Spectranetics Corporation Medical device handle
US9456872B2 (en) 2013-03-13 2016-10-04 The Spectranetics Corporation Laser ablation catheter
USD770616S1 (en) 2015-02-20 2016-11-01 The Spectranetics Corporation Medical device handle
US9603618B2 (en) 2013-03-15 2017-03-28 The Spectranetics Corporation Medical device for removing an implanted object
US9668765B2 (en) 2013-03-15 2017-06-06 The Spectranetics Corporation Retractable blade for lead removal device
US9883885B2 (en) 2013-03-13 2018-02-06 The Spectranetics Corporation System and method of ablative cutting and pulsed vacuum aspiration
US9925366B2 (en) 2013-03-15 2018-03-27 The Spectranetics Corporation Surgical instrument for removing an implanted object
US9980743B2 (en) 2013-03-15 2018-05-29 The Spectranetics Corporation Medical device for removing an implanted object using laser cut hypotubes
US10123803B2 (en) 2007-10-17 2018-11-13 Covidien Lp Methods of managing neurovascular obstructions
US10136913B2 (en) 2013-03-15 2018-11-27 The Spectranetics Corporation Multiple configuration surgical cutting device
US10383691B2 (en) 2013-03-13 2019-08-20 The Spectranetics Corporation Last catheter with helical internal lumen
US10405924B2 (en) 2014-05-30 2019-09-10 The Spectranetics Corporation System and method of ablative cutting and vacuum aspiration through primary orifice and auxiliary side port
US10448999B2 (en) 2013-03-15 2019-10-22 The Spectranetics Corporation Surgical instrument for removing an implanted object
US10722255B2 (en) 2008-12-23 2020-07-28 Covidien Lp Systems and methods for removing obstructive matter from body lumens and treating vascular defects
US10835279B2 (en) 2013-03-14 2020-11-17 Spectranetics Llc Distal end supported tissue slitting apparatus
US10842532B2 (en) 2013-03-15 2020-11-24 Spectranetics Llc Medical device for removing an implanted object
US11337714B2 (en) 2007-10-17 2022-05-24 Covidien Lp Restoring blood flow and clot removal during acute ischemic stroke
US11925334B2 (en) 2020-11-30 2024-03-12 Spectranetics Llc Surgical instrument for removing an implanted object

Families Citing this family (143)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7491216B2 (en) 1997-11-07 2009-02-17 Salviac Limited Filter element with retractable guidewire tip
IES81060B2 (en) 1997-11-07 2000-01-12 Salviac Ltd An embolic protection device
US7314477B1 (en) 1998-09-25 2008-01-01 C.R. Bard Inc. Removable embolus blood clot filter and filter delivery unit
US6964672B2 (en) 1999-05-07 2005-11-15 Salviac Limited Support frame for an embolic protection device
US6918921B2 (en) 1999-05-07 2005-07-19 Salviac Limited Support frame for an embolic protection device
US9113936B2 (en) * 1999-12-23 2015-08-25 Abbott Laboratories Snare
GB2369575A (en) 2000-04-20 2002-06-05 Salviac Ltd An embolic protection system
EP1455681B1 (en) 2001-12-21 2014-09-17 Salviac Limited A support frame for an embolic protection device
US9204956B2 (en) 2002-02-20 2015-12-08 C. R. Bard, Inc. IVC filter with translating hooks
US7029440B2 (en) * 2002-03-13 2006-04-18 Scimed Life Systems, Inc. Distal protection filter and method of manufacture
US7172614B2 (en) * 2002-06-27 2007-02-06 Advanced Cardiovascular Systems, Inc. Support structures for embolic filtering devices
DE10233085B4 (en) 2002-07-19 2014-02-20 Dendron Gmbh Stent with guide wire
US20040082947A1 (en) 2002-10-25 2004-04-29 The Regents Of The University Of Michigan Ablation catheters
US20050033137A1 (en) * 2002-10-25 2005-02-10 The Regents Of The University Of Michigan Ablation catheters and methods for their use
CA2564378A1 (en) * 2004-05-06 2005-11-17 Boston Scientific Limited Variable size retrieval basket
EP1750619B1 (en) 2004-05-25 2013-07-24 Covidien LP Flexible vascular occluding device
US20060206200A1 (en) 2004-05-25 2006-09-14 Chestnut Medical Technologies, Inc. Flexible vascular occluding device
US8628564B2 (en) 2004-05-25 2014-01-14 Covidien Lp Methods and apparatus for luminal stenting
AU2010236494B2 (en) 2004-05-25 2013-05-30 Covidien Lp Vascular stenting for aneurysms
US8617234B2 (en) 2004-05-25 2013-12-31 Covidien Lp Flexible vascular occluding device
US7704267B2 (en) 2004-08-04 2010-04-27 C. R. Bard, Inc. Non-entangling vena cava filter
US9655633B2 (en) * 2004-09-10 2017-05-23 Penumbra, Inc. System and method for treating ischemic stroke
US8366735B2 (en) 2004-09-10 2013-02-05 Penumbra, Inc. System and method for treating ischemic stroke
US8795315B2 (en) 2004-10-06 2014-08-05 Cook Medical Technologies Llc Emboli capturing device having a coil and method for capturing emboli
US20060089637A1 (en) 2004-10-14 2006-04-27 Werneth Randell L Ablation catheter
US7794473B2 (en) 2004-11-12 2010-09-14 C.R. Bard, Inc. Filter delivery system
US8617152B2 (en) 2004-11-15 2013-12-31 Medtronic Ablation Frontiers Llc Ablation system with feedback
US7429261B2 (en) 2004-11-24 2008-09-30 Ablation Frontiers, Inc. Atrial ablation catheter and method of use
US7468062B2 (en) 2004-11-24 2008-12-23 Ablation Frontiers, Inc. Atrial ablation catheter adapted for treatment of septal wall arrhythmogenic foci and method of use
US8267954B2 (en) 2005-02-04 2012-09-18 C. R. Bard, Inc. Vascular filter with sensing capability
US8945169B2 (en) 2005-03-15 2015-02-03 Cook Medical Technologies Llc Embolic protection device
US8221446B2 (en) 2005-03-15 2012-07-17 Cook Medical Technologies Embolic protection device
US7967838B2 (en) 2005-05-12 2011-06-28 C. R. Bard, Inc. Removable embolus blood clot filter
EP1883371B1 (en) 2005-05-25 2015-10-07 Covidien LP System and method for delivering and deploying and occluding device within a vessel
US7850708B2 (en) 2005-06-20 2010-12-14 Cook Incorporated Embolic protection device having a reticulated body with staggered struts
EP2759276A1 (en) 2005-06-20 2014-07-30 Medtronic Ablation Frontiers LLC Ablation catheter
US8109962B2 (en) 2005-06-20 2012-02-07 Cook Medical Technologies Llc Retrievable device having a reticulation portion with staggered struts
CA2615267A1 (en) 2005-07-11 2007-01-18 Ablation Frontiers, Inc. Low power tissue ablation system
US7771452B2 (en) 2005-07-12 2010-08-10 Cook Incorporated Embolic protection device with a filter bag that disengages from a basket
US7766934B2 (en) 2005-07-12 2010-08-03 Cook Incorporated Embolic protection device with an integral basket and bag
US8187298B2 (en) 2005-08-04 2012-05-29 Cook Medical Technologies Llc Embolic protection device having inflatable frame
US8062327B2 (en) 2005-08-09 2011-11-22 C. R. Bard, Inc. Embolus blood clot filter and delivery system
US8657814B2 (en) 2005-08-22 2014-02-25 Medtronic Ablation Frontiers Llc User interface for tissue ablation system
US8377092B2 (en) 2005-09-16 2013-02-19 Cook Medical Technologies Llc Embolic protection device
US8632562B2 (en) 2005-10-03 2014-01-21 Cook Medical Technologies Llc Embolic protection device
US8182508B2 (en) 2005-10-04 2012-05-22 Cook Medical Technologies Llc Embolic protection device
US8252017B2 (en) 2005-10-18 2012-08-28 Cook Medical Technologies Llc Invertible filter for embolic protection
US8216269B2 (en) 2005-11-02 2012-07-10 Cook Medical Technologies Llc Embolic protection device having reduced profile
US8152831B2 (en) 2005-11-17 2012-04-10 Cook Medical Technologies Llc Foam embolic protection device
JP2009519731A (en) 2005-11-18 2009-05-21 シー・アール・バード・インコーポレイテツド Vena cava filter with filament
US20070162108A1 (en) * 2005-12-13 2007-07-12 Carlson James M Implantable medical device using palladium
US20070225749A1 (en) * 2006-02-03 2007-09-27 Martin Brian B Methods and devices for restoring blood flow within blocked vasculature
US8152833B2 (en) 2006-02-22 2012-04-10 Tyco Healthcare Group Lp Embolic protection systems having radiopaque filter mesh
WO2007133366A2 (en) 2006-05-02 2007-11-22 C. R. Bard, Inc. Vena cava filter formed from a sheet
CA2655158A1 (en) 2006-06-05 2007-12-13 C.R. Bard Inc. Embolus blood clot filter utilizable with a single delivery system or a single retrieval system in one of a femoral or jugular access
US20070288054A1 (en) * 2006-06-13 2007-12-13 Tanaka Don A Vascular thrombectomby apparatus and method of use
US20080071307A1 (en) 2006-09-19 2008-03-20 Cook Incorporated Apparatus and methods for in situ embolic protection
US20080269774A1 (en) 2006-10-26 2008-10-30 Chestnut Medical Technologies, Inc. Intracorporeal Grasping Device
US9901434B2 (en) 2007-02-27 2018-02-27 Cook Medical Technologies Llc Embolic protection device including a Z-stent waist band
US8795351B2 (en) 2007-04-13 2014-08-05 C.R. Bard, Inc. Migration resistant embolic filter
US10076346B2 (en) 2007-04-17 2018-09-18 Covidien Lp Complex wire formed devices
US10064635B2 (en) * 2007-04-17 2018-09-04 Covidien Lp Articulating retrieval devices
US8512352B2 (en) 2007-04-17 2013-08-20 Lazarus Effect, Inc. Complex wire formed devices
US11202646B2 (en) 2007-04-17 2021-12-21 Covidien Lp Articulating retrieval devices
US8641704B2 (en) 2007-05-11 2014-02-04 Medtronic Ablation Frontiers Llc Ablation therapy system and method for treating continuous atrial fibrillation
US8252018B2 (en) 2007-09-14 2012-08-28 Cook Medical Technologies Llc Helical embolic protection device
US8419748B2 (en) 2007-09-14 2013-04-16 Cook Medical Technologies Llc Helical thrombus removal device
US9138307B2 (en) 2007-09-14 2015-09-22 Cook Medical Technologies Llc Expandable device for treatment of a stricture in a body vessel
US20100256600A1 (en) * 2009-04-04 2010-10-07 Ferrera David A Neurovascular otw pta balloon catheter and delivery system
US20100174309A1 (en) * 2008-05-19 2010-07-08 Mindframe, Inc. Recanalization/revascularization and embolus addressing systems including expandable tip neuro-microcatheter
WO2009086482A1 (en) 2007-12-26 2009-07-09 Lazarus Effect, Inc. Retrieval systems and methods for use thereof
WO2009089297A2 (en) * 2008-01-07 2009-07-16 Intersect Partners, Llc Novel enhanced ptna rapid exchange type of catheter system
EP2341845B1 (en) * 2008-07-22 2016-01-06 Neuravi Limited Clot capture systems
US9402707B2 (en) 2008-07-22 2016-08-02 Neuravi Limited Clot capture systems and associated methods
US8388644B2 (en) 2008-12-29 2013-03-05 Cook Medical Technologies Llc Embolic protection device and method of use
US20100191168A1 (en) 2009-01-29 2010-07-29 Trustees Of Tufts College Endovascular cerebrospinal fluid shunt
EP2403583B1 (en) 2009-03-06 2016-10-19 Lazarus Effect, Inc. Retrieval systems
EP3505136A1 (en) * 2009-07-29 2019-07-03 C.R. Bard Inc. Tubular filter
US8801748B2 (en) 2010-01-22 2014-08-12 Lazarus Effect, Inc. Retrieval systems and methods for use thereof
WO2012009675A2 (en) 2010-07-15 2012-01-19 Lazarus Effect, Inc. Retrieval systems and methods for use thereof
US9039749B2 (en) 2010-10-01 2015-05-26 Covidien Lp Methods and apparatuses for flow restoration and implanting members in the human body
WO2012052982A1 (en) 2010-10-22 2012-04-26 Neuravi Limited Clot engagement and removal system
EP2683309B1 (en) 2011-03-09 2021-04-21 Neuravi Limited A clot retrieval device for removing occlusive clot from a blood vessel
US11259824B2 (en) 2011-03-09 2022-03-01 Neuravi Limited Clot retrieval device for removing occlusive clot from a blood vessel
EP3741314B1 (en) 2011-05-23 2022-12-21 Covidien LP Retrieval systems
US8897856B2 (en) * 2011-11-26 2014-11-25 Angelo Gaitas Atherosclerosis therapy via delivery and localized heating of micro size particles
JP6069348B2 (en) 2011-12-16 2017-02-01 ストライカー コーポレイションStryker Corporation Embolization removal cage
US9114001B2 (en) 2012-10-30 2015-08-25 Covidien Lp Systems for attaining a predetermined porosity of a vascular device
US9452070B2 (en) 2012-10-31 2016-09-27 Covidien Lp Methods and systems for increasing a density of a region of a vascular device
US9943427B2 (en) 2012-11-06 2018-04-17 Covidien Lp Shaped occluding devices and methods of using the same
US9157174B2 (en) 2013-02-05 2015-10-13 Covidien Lp Vascular device for aneurysm treatment and providing blood flow into a perforator vessel
US9642635B2 (en) 2013-03-13 2017-05-09 Neuravi Limited Clot removal device
US9433429B2 (en) 2013-03-14 2016-09-06 Neuravi Limited Clot retrieval devices
WO2014140092A2 (en) 2013-03-14 2014-09-18 Neuravi Limited Devices and methods for removal of acute blockages from blood vessels
TR201820525T4 (en) 2013-03-14 2019-01-21 Neuravi Ltd A clot removal device for removing an occlusive clot from a blood vessel.
US10076399B2 (en) 2013-09-13 2018-09-18 Covidien Lp Endovascular device engagement
US9737696B2 (en) 2014-01-15 2017-08-22 Tufts Medical Center, Inc. Endovascular cerebrospinal fluid shunt
EP3998100A1 (en) 2014-01-15 2022-05-18 Tufts Medical Center, Inc. Endovascular cerebrospinal fluid shunt system
US10285720B2 (en) 2014-03-11 2019-05-14 Neuravi Limited Clot retrieval system for removing occlusive clot from a blood vessel
US10441301B2 (en) 2014-06-13 2019-10-15 Neuravi Limited Devices and methods for removal of acute blockages from blood vessels
US10792056B2 (en) 2014-06-13 2020-10-06 Neuravi Limited Devices and methods for removal of acute blockages from blood vessels
US10265086B2 (en) 2014-06-30 2019-04-23 Neuravi Limited System for removing a clot from a blood vessel
CN107148293B (en) 2014-10-31 2020-08-11 西瑞维斯克有限责任公司 Methods and systems for treating hydrocephalus
ES2920773T3 (en) 2014-11-26 2022-08-09 Neuravi Ltd A clot removal device to remove an occlusive clot from a blood vessel
US10617435B2 (en) 2014-11-26 2020-04-14 Neuravi Limited Clot retrieval device for removing clot from a blood vessel
US11253278B2 (en) 2014-11-26 2022-02-22 Neuravi Limited Clot retrieval system for removing occlusive clot from a blood vessel
WO2016130647A1 (en) 2015-02-11 2016-08-18 Lazarus Effect, Inc. Expandable tip medical devices and methods
US9570318B1 (en) * 2015-07-22 2017-02-14 International Business Machines Corporation High-k and p-type work function metal first fabrication process having improved annealing process flows
CN108136164B (en) 2015-10-30 2020-12-08 西瑞维斯克公司 Systems and methods for treating hydrocephalus
JP7086935B2 (en) 2016-08-17 2022-06-20 ニューラヴィ・リミテッド Thrombus recovery system for removing thromboangiitis obliterans from blood vessels
AU2017324233A1 (en) 2016-09-06 2019-04-04 Neuravi Limited A clot retrieval device for removing occlusive clot from a blood vessel
US9993257B2 (en) * 2016-09-07 2018-06-12 NeuroVarc Technologies Inc. Clot retrieval device for ischemic stroke treatment
US11298145B2 (en) 2017-05-12 2022-04-12 Covidien Lp Retrieval of material from vessel lumens
US11191555B2 (en) 2017-05-12 2021-12-07 Covidien Lp Retrieval of material from vessel lumens
US10722257B2 (en) 2017-05-12 2020-07-28 Covidien Lp Retrieval of material from vessel lumens
US10709464B2 (en) 2017-05-12 2020-07-14 Covidien Lp Retrieval of material from vessel lumens
US11129630B2 (en) 2017-05-12 2021-09-28 Covidien Lp Retrieval of material from vessel lumens
WO2018232044A1 (en) 2017-06-12 2018-12-20 Covidien Lp Tools for sheathing treatment devices and associated systems and methods
US10478322B2 (en) 2017-06-19 2019-11-19 Covidien Lp Retractor device for transforming a retrieval device from a deployed position to a delivery position
US10575864B2 (en) 2017-06-22 2020-03-03 Covidien Lp Securing element for resheathing an intravascular device and associated systems and methods
US11013900B2 (en) 2018-03-08 2021-05-25 CereVasc, Inc. Systems and methods for minimally invasive drug delivery to a subarachnoid space
US10842498B2 (en) 2018-09-13 2020-11-24 Neuravi Limited Systems and methods of restoring perfusion to a vessel
US11406416B2 (en) 2018-10-02 2022-08-09 Neuravi Limited Joint assembly for vasculature obstruction capture device
ES2910600T3 (en) 2019-03-04 2022-05-12 Neuravi Ltd Powered Clot Recovery Catheter
JP2021041169A (en) 2019-09-11 2021-03-18 ニューラヴィ・リミテッド Expandable mouth catheter
US11712231B2 (en) 2019-10-29 2023-08-01 Neuravi Limited Proximal locking assembly design for dual stent mechanical thrombectomy device
US11839725B2 (en) 2019-11-27 2023-12-12 Neuravi Limited Clot retrieval device with outer sheath and inner catheter
US11779364B2 (en) 2019-11-27 2023-10-10 Neuravi Limited Actuated expandable mouth thrombectomy catheter
US11517340B2 (en) 2019-12-03 2022-12-06 Neuravi Limited Stentriever devices for removing an occlusive clot from a vessel and methods thereof
US11633198B2 (en) 2020-03-05 2023-04-25 Neuravi Limited Catheter proximal joint
US11883043B2 (en) 2020-03-31 2024-01-30 DePuy Synthes Products, Inc. Catheter funnel extension
US11759217B2 (en) 2020-04-07 2023-09-19 Neuravi Limited Catheter tubular support
US11717308B2 (en) 2020-04-17 2023-08-08 Neuravi Limited Clot retrieval device for removing heterogeneous clots from a blood vessel
US11871946B2 (en) 2020-04-17 2024-01-16 Neuravi Limited Clot retrieval device for removing clot from a blood vessel
US11730501B2 (en) 2020-04-17 2023-08-22 Neuravi Limited Floating clot retrieval device for removing clots from a blood vessel
CN116075274A (en) * 2020-06-05 2023-05-05 格拉维蒂医疗技术有限公司 Method and apparatus for restoring flow
US11737771B2 (en) 2020-06-18 2023-08-29 Neuravi Limited Dual channel thrombectomy device
US11439418B2 (en) 2020-06-23 2022-09-13 Neuravi Limited Clot retrieval device for removing clot from a blood vessel
US11395669B2 (en) 2020-06-23 2022-07-26 Neuravi Limited Clot retrieval device with flexible collapsible frame
US11864781B2 (en) 2020-09-23 2024-01-09 Neuravi Limited Rotating frame thrombectomy device
US11872354B2 (en) 2021-02-24 2024-01-16 Neuravi Limited Flexible catheter shaft frame with seam
EP4329643A1 (en) 2021-04-27 2024-03-06 Contego Medical, Inc. Thrombus aspiration system and methods for controlling blood loss
US20220361942A1 (en) * 2021-05-13 2022-11-17 Biosense Webster (Israel) Ltd. Distal Assembly for Catheter with Lumens Running Along Spines

Citations (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5509923A (en) * 1989-08-16 1996-04-23 Raychem Corporation Device for dissecting, grasping, or cutting an object
US5549626A (en) * 1994-12-23 1996-08-27 New York Society For The Ruptured And Crippled Maintaining The Hospital For Special Surgery Vena caval filter
US5601572A (en) * 1989-08-16 1997-02-11 Raychem Corporation Device or apparatus for manipulating matter having a elastic ring clip
US5681347A (en) * 1995-05-23 1997-10-28 Boston Scientific Corporation Vena cava filter delivery system
US5695518A (en) * 1990-12-28 1997-12-09 Laerum; Frode Filtering device for preventing embolism and/or distension of blood vessel walls
US5720754A (en) * 1989-08-16 1998-02-24 Medtronic, Inc. Device or apparatus for manipulating matter
US5720764A (en) * 1994-06-11 1998-02-24 Naderlinger; Eduard Vena cava thrombus filter
US5792156A (en) * 1995-06-27 1998-08-11 Laboratoire Perouse Implant Instrument for vascular surgery and its use
US5810874A (en) * 1996-02-22 1998-09-22 Cordis Corporation Temporary filter catheter
US5820628A (en) * 1989-08-16 1998-10-13 Medtronic, Inc. Device or apparatus for manipulating matter
US5895398A (en) * 1996-02-02 1999-04-20 The Regents Of The University Of California Method of using a clot capture coil
US5902263A (en) * 1997-02-12 1999-05-11 Prolifix Medical, Inc. Apparatus and method for removing stenotic material from stents
US5904690A (en) * 1989-08-16 1999-05-18 Medtronic, Inc. Device or apparatus for manipulating matter
US6053932A (en) * 1997-03-06 2000-04-25 Scimed Life Systems, Inc. Distal protection device
US6168603B1 (en) * 1995-02-02 2001-01-02 Boston Scientific Corporation Surgical extractor
US6443972B1 (en) * 1997-11-19 2002-09-03 Cordis Europa N.V. Vascular filter
US6551342B1 (en) * 2001-08-24 2003-04-22 Endovascular Technologies, Inc. Embolic filter

Family Cites Families (504)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US444531A (en) * 1891-01-13 greene
US2943626A (en) 1957-01-31 1960-07-05 Dormia Enrico Instruments for the extraction of foreign bodies
US3952747A (en) 1974-03-28 1976-04-27 Kimmell Jr Garman O Filter and filter insertion instrument
DE2821048C2 (en) 1978-05-13 1980-07-17 Willy Ruesch Gmbh & Co Kg, 7053 Kernen Medical instrument
IT1126526B (en) 1979-12-07 1986-05-21 Enrico Dormia SURGICAL EXTRACTOR TO REMOVE FOREIGN BODIES THAT ARE FOUND IN THE NATURAL ROUTES OF THE HUMAN BODY, AS CALCULATIONS AND SIMILAR
NZ201207A (en) 1981-07-23 1984-11-09 British Petroleum Co Plc Zeolite-based catalyst production and use
US4643184A (en) * 1982-09-29 1987-02-17 Mobin Uddin Kazi Embolus trap
US4494531A (en) 1982-12-06 1985-01-22 Cook, Incorporated Expandable blood clot filter
US4611594A (en) 1984-04-11 1986-09-16 Northwestern University Medical instrument for containment and removal of calculi
US4727873A (en) 1984-04-17 1988-03-01 Mobin Uddin Kazi Embolus trap
DK151404C (en) 1984-05-23 1988-07-18 Cook Europ Aps William FULLY FILTER FOR IMPLANTATION IN A PATIENT'S BLOOD
IT1176442B (en) 1984-07-20 1987-08-18 Enrico Dormia INSTRUMENT FOR THE EXTRACTION OF FOREIGN BODIES FROM THE BODY'S PHYSIOLOGICAL CHANNELS
FR2573646B1 (en) 1984-11-29 1988-11-25 Celsa Composants Electr Sa PERFECTED FILTER, PARTICULARLY FOR THE RETENTION OF BLOOD CLOTS
US4790813A (en) 1984-12-17 1988-12-13 Intravascular Surgical Instruments, Inc. Method and apparatus for surgically removing remote deposits
FR2580504B1 (en) 1985-04-22 1987-07-10 Pieronne Alain FILTER FOR THE PARTIAL AND AT LEAST PROVISIONAL INTERRUPTION OF A VEIN AND CATHETER CARRYING THE FILTER
US4706671A (en) 1985-05-02 1987-11-17 Weinrib Harry P Catheter with coiled tip
US4662885A (en) 1985-09-03 1987-05-05 Becton, Dickinson And Company Percutaneously deliverable intravascular filter prosthesis
US4650466A (en) 1985-11-01 1987-03-17 Angiobrade Partners Angioplasty device
US4790812A (en) 1985-11-15 1988-12-13 Hawkins Jr Irvin F Apparatus and method for removing a target object from a body passsageway
US4723549A (en) * 1986-09-18 1988-02-09 Wholey Mark H Method and apparatus for dilating blood vessels
FR2606641B1 (en) 1986-11-17 1991-07-12 Promed FILTERING DEVICE FOR BLOOD CLOTS
US4794928A (en) * 1987-06-10 1989-01-03 Kletschka Harold D Angioplasty device and method of using the same
JPH052166Y2 (en) 1987-07-10 1993-01-20
US5154705A (en) * 1987-09-30 1992-10-13 Lake Region Manufacturing Co., Inc. Hollow lumen cable apparatus
US4873978A (en) 1987-12-04 1989-10-17 Robert Ginsburg Device and method for emboli retrieval
FR2624747A1 (en) 1987-12-18 1989-06-23 Delsanti Gerard REMOVABLE ENDO-ARTERIAL DEVICES FOR REPAIRING ARTERIAL WALL DECOLLEMENTS
US4921478A (en) 1988-02-23 1990-05-01 C. R. Bard, Inc. Cerebral balloon angioplasty system
FR2632848A1 (en) 1988-06-21 1989-12-22 Lefebvre Jean Marie FILTER FOR MEDICAL USE
US4832055A (en) 1988-07-08 1989-05-23 Palestrant Aubrey M Mechanically locking blood clot filter
US4921484A (en) 1988-07-25 1990-05-01 Cordis Corporation Mesh balloon catheter device
US5152777A (en) 1989-01-25 1992-10-06 Uresil Corporation Device and method for providing protection from emboli and preventing occulsion of blood vessels
US4969891A (en) 1989-03-06 1990-11-13 Gewertz Bruce L Removable vascular filter
DE8910603U1 (en) 1989-09-06 1989-12-07 Guenther, Rolf W., Prof. Dr.
US5100425A (en) 1989-09-14 1992-03-31 Medintec R&D Limited Partnership Expandable transluminal atherectomy catheter system and method for the treatment of arterial stenoses
US4997435A (en) 1989-09-25 1991-03-05 Methodist Hospital Of Indiana Inc. Percutaneous catheter with encapsulating receptacle
US5092839A (en) 1989-09-29 1992-03-03 Kipperman Robert M Coronary thrombectomy
AU6376190A (en) 1989-10-25 1991-05-02 C.R. Bard Inc. Occluding catheter and methods for treating cerebral arteries
US5421832A (en) 1989-12-13 1995-06-06 Lefebvre; Jean-Marie Filter-catheter and method of manufacturing same
US5221261A (en) 1990-04-12 1993-06-22 Schneider (Usa) Inc. Radially expandable fixation member
US5071407A (en) 1990-04-12 1991-12-10 Schneider (U.S.A.) Inc. Radially expandable fixation member
US5158548A (en) 1990-04-25 1992-10-27 Advanced Cardiovascular Systems, Inc. Method and system for stent delivery
US5171233A (en) 1990-04-25 1992-12-15 Microvena Corporation Snare-type probe
FR2663217B1 (en) 1990-06-15 1992-10-16 Antheor FILTERING DEVICE FOR THE PREVENTION OF EMBOLIES.
CA2048307C (en) 1990-08-14 1998-08-18 Rolf Gunther Method and apparatus for filtering blood in a blood vessel of a patient
US5160342A (en) 1990-08-16 1992-11-03 Evi Corp. Endovascular filter and method for use thereof
US5108419A (en) 1990-08-16 1992-04-28 Evi Corporation Endovascular filter and method for use thereof
US5100423A (en) 1990-08-21 1992-03-31 Medical Engineering & Development Institute, Inc. Ablation catheter
US5064428A (en) 1990-09-18 1991-11-12 Cook Incorporated Medical retrieval basket
US5053008A (en) 1990-11-21 1991-10-01 Sandeep Bajaj Intracardiac catheter
US5350398A (en) 1991-05-13 1994-09-27 Dusan Pavcnik Self-expanding filter for percutaneous insertion
ES2127756T3 (en) 1991-06-17 1999-05-01 Wilson Cook Medical Inc ENDOSCOPIC EXTRACTION DEVICE WITH A COMPOSITE METALLIC FILAR STRUCTURE.
DE9109006U1 (en) 1991-07-22 1991-10-10 Schmitz-Rode, Thomas, Dipl.-Ing. Dr.Med., 5100 Aachen, De
US5192286A (en) 1991-07-26 1993-03-09 Regents Of The University Of California Method and device for retrieving materials from body lumens
US5626605A (en) 1991-12-30 1997-05-06 Scimed Life Systems, Inc. Thrombosis filter
FR2689388B1 (en) 1992-04-07 1999-07-16 Celsa Lg PERFECTIONALLY RESORBABLE BLOOD FILTER.
US5324304A (en) 1992-06-18 1994-06-28 William Cook Europe A/S Introduction catheter set for a collapsible self-expandable implant
US5527338A (en) 1992-09-02 1996-06-18 Board Of Regents, The University Of Texas System Intravascular device
FR2696092B1 (en) 1992-09-28 1994-12-30 Lefebvre Jean Marie Kit for medical use composed of a filter and its device for placement in the vessel.
US5792157A (en) 1992-11-13 1998-08-11 Scimed Life Systems, Inc. Expandable intravascular occlusion material removal devices and methods of use
US5501694A (en) 1992-11-13 1996-03-26 Scimed Life Systems, Inc. Expandable intravascular occlusion material removal devices and methods of use
US5836868A (en) 1992-11-13 1998-11-17 Scimed Life Systems, Inc. Expandable intravascular occlusion material removal devices and methods of use
US5490859A (en) * 1992-11-13 1996-02-13 Scimed Life Systems, Inc. Expandable intravascular occlusion material removal devices and methods of use
FR2699809B1 (en) 1992-12-28 1995-02-17 Celsa Lg Device which can selectively constitute a temporary blood filter.
DE69433774T2 (en) 1993-02-19 2005-04-14 Boston Scientific Corp., Natick SURGICAL EXTRACTOR
US5897567A (en) 1993-04-29 1999-04-27 Scimed Life Systems, Inc. Expandable intravascular occlusion material removal devices and methods of use
US5634942A (en) 1994-04-21 1997-06-03 B. Braun Celsa Assembly comprising a blood filter for temporary or definitive use and a device for implanting it
WO1996001591A1 (en) 1994-07-08 1996-01-25 Microvena Corporation Method of forming medical devices; intravascular occlusion devices
US6123715A (en) 1994-07-08 2000-09-26 Amplatz; Curtis Method of forming medical devices; intravascular occlusion devices
US5601595A (en) 1994-10-25 1997-02-11 Scimed Life Systems, Inc. Remobable thrombus filter
US5658296A (en) 1994-11-21 1997-08-19 Boston Scientific Corporation Method for making surgical retrieval baskets
US5709704A (en) * 1994-11-30 1998-01-20 Boston Scientific Corporation Blood clot filtering
US6013093A (en) * 1995-11-28 2000-01-11 Boston Scientific Corporation Blood clot filtering
US5690671A (en) 1994-12-13 1997-11-25 Micro Interventional Systems, Inc. Embolic elements and methods and apparatus for their delivery
US6348056B1 (en) * 1999-08-06 2002-02-19 Scimed Life Systems, Inc. Medical retrieval device with releasable retrieval basket
ES2148362T3 (en) * 1995-03-02 2000-10-16 Schneider Europ Gmbh METHOD TO MANUFACTURE A GUIDE WIRE.
US5795322A (en) 1995-04-10 1998-08-18 Cordis Corporation Catheter with filter and thrombus-discharge device
DE69629865T2 (en) 1995-04-14 2004-07-15 B. Braun Medical Sas Intraluminal medical device, especially blood filter
US5833650A (en) 1995-06-05 1998-11-10 Percusurge, Inc. Catheter apparatus and method for treating occluded vessels
TW438587B (en) 1995-06-20 2001-06-07 Takeda Chemical Industries Ltd A pharmaceutical composition for prophylaxis and treatment of diabetes
FR2737654B1 (en) 1995-08-10 1997-11-21 Braun Celsa Sa FILTRATION UNIT FOR THE RETENTION OF BLOOD CLOTS
US5779716A (en) 1995-10-06 1998-07-14 Metamorphic Surgical Devices, Inc. Device for removing solid objects from body canals, cavities and organs
US6264663B1 (en) 1995-10-06 2001-07-24 Metamorphic Surgical Devices, Llc Device for removing solid objects from body canals, cavities and organs including an invertable basket
US6168604B1 (en) * 1995-10-06 2001-01-02 Metamorphic Surgical Devices, Llc Guide wire device for removing solid objects from body canals
US5989281A (en) 1995-11-07 1999-11-23 Embol-X, Inc. Cannula with associated filter and methods of use during cardiac surgery
US5769816A (en) 1995-11-07 1998-06-23 Embol-X, Inc. Cannula with associated filter
US5695519A (en) 1995-11-30 1997-12-09 American Biomed, Inc. Percutaneous filter for carotid angioplasty
EP0879068A4 (en) 1996-02-02 1999-04-21 Transvascular Inc Methods and apparatus for blocking flow through blood vessels
US5846251A (en) 1996-07-22 1998-12-08 Hart; Charles C. Access device with expandable containment member
US6096053A (en) 1996-05-03 2000-08-01 Scimed Life Systems, Inc. Medical retrieval basket
US6800080B1 (en) 1996-05-03 2004-10-05 Scimed Life Systems, Inc. Medical retrieval device
US5935139A (en) 1996-05-03 1999-08-10 Boston Scientific Corporation System for immobilizing or manipulating an object in a tract
EP0897288A4 (en) 1996-05-14 2000-04-05 Embol X Inc Aortic occluder with associated filter and methods of use during cardiac surgery
US20050245894A1 (en) 1996-05-20 2005-11-03 Medtronic Vascular, Inc. Methods and apparatuses for drug delivery to an intravascular occlusion
US6022336A (en) * 1996-05-20 2000-02-08 Percusurge, Inc. Catheter system for emboli containment
US6652480B1 (en) 1997-03-06 2003-11-25 Medtronic Ave., Inc. Methods for reducing distal embolization
ATE285812T1 (en) 1996-05-20 2005-01-15 Medtronic Percusurge Inc LOW PROFILE CATHETER VALVE
US6270477B1 (en) 1996-05-20 2001-08-07 Percusurge, Inc. Catheter for emboli containment
US6544276B1 (en) 1996-05-20 2003-04-08 Medtronic Ave. Inc. Exchange method for emboli containment
NL1003497C2 (en) 1996-07-03 1998-01-07 Cordis Europ Catheter with temporary vena-cava filter.
US5662671A (en) 1996-07-17 1997-09-02 Embol-X, Inc. Atherectomy device having trapping and excising means for removal of plaque from the aorta and other arteries
US5669933A (en) 1996-07-17 1997-09-23 Nitinol Medical Technologies, Inc. Removable embolus blood clot filter
US6066158A (en) 1996-07-25 2000-05-23 Target Therapeutics, Inc. Mechanical clot encasing and removal wire
US6447530B1 (en) 1996-11-27 2002-09-10 Scimed Life Systems, Inc. Atraumatic anchoring and disengagement mechanism for permanent implant device
US5876367A (en) 1996-12-05 1999-03-02 Embol-X, Inc. Cerebral protection during carotid endarterectomy and downstream vascular protection during other surgeries
FR2758078B1 (en) 1997-01-03 1999-07-16 Braun Celsa Sa BLOOD FILTER WITH IMPROVED PERMEABILITY
US5776162A (en) 1997-01-03 1998-07-07 Nitinol Medical Technologies, Inc. Vessel implantable shape memory appliance with superelastic hinged joint
US6391044B1 (en) 1997-02-03 2002-05-21 Angioguard, Inc. Vascular filter system
EP1226796B1 (en) 1997-02-03 2005-06-01 Angioguard, Inc. Vascular filter
US20020169458A1 (en) 1997-02-06 2002-11-14 Connors John J. ICA angioplasty with cerebral protection
US6295989B1 (en) 1997-02-06 2001-10-02 Arteria Medical Science, Inc. ICA angioplasty with cerebral protection
US6254633B1 (en) 1997-02-12 2001-07-03 Corvita Corporation Delivery device for a medical device having a constricted region
WO1998034673A1 (en) 1997-02-12 1998-08-13 Prolifix Medical, Inc. Apparatus for removal of material from stents
US5800457A (en) 1997-03-05 1998-09-01 Gelbfish; Gary A. Intravascular filter and associated methodology
US7094249B1 (en) 1997-03-06 2006-08-22 Boston Scientific Scimed, Inc. Distal protection device and method
EP0934092A4 (en) 1997-03-06 2008-03-26 Boston Scient Scimed Inc Distal protection device and method
US5827324A (en) 1997-03-06 1998-10-27 Scimed Life Systems, Inc. Distal protection device
US6152946A (en) 1998-03-05 2000-11-28 Scimed Life Systems, Inc. Distal protection device and method
US6974469B2 (en) 1997-03-06 2005-12-13 Scimed Life Systems, Inc. Distal protection device and method
US5772674A (en) 1997-03-31 1998-06-30 Nakhjavan; Fred K. Catheter for removal of clots in blood vessels
WO1998047447A1 (en) 1997-04-23 1998-10-29 Dubrul William R Bifurcated stent and distal protection system
US5868708A (en) * 1997-05-07 1999-02-09 Applied Medical Resources Corporation Balloon catheter apparatus and method
US6676682B1 (en) 1997-05-08 2004-01-13 Scimed Life Systems, Inc. Percutaneous catheter and guidewire having filter and medical device deployment capabilities
US5846260A (en) 1997-05-08 1998-12-08 Embol-X, Inc. Cannula with a modular filter for filtering embolic material
US5911734A (en) 1997-05-08 1999-06-15 Embol-X, Inc. Percutaneous catheter and guidewire having filter and medical device deployment capabilities
US6258120B1 (en) 1997-12-23 2001-07-10 Embol-X, Inc. Implantable cerebral protection device and methods of use
US5954745A (en) 1997-05-16 1999-09-21 Gertler; Jonathan Catheter-filter set having a compliant seal
US6059814A (en) 1997-06-02 2000-05-09 Medtronic Ave., Inc. Filter for filtering fluid in a bodily passageway
US6761727B1 (en) * 1997-06-02 2004-07-13 Medtronic Ave, Inc. Filter assembly
US5800525A (en) 1997-06-04 1998-09-01 Vascular Science, Inc. Blood filter
US5848964A (en) 1997-06-06 1998-12-15 Samuels; Shaun Lawrence Wilkie Temporary inflatable filter device and method of use
US6245088B1 (en) 1997-07-07 2001-06-12 Samuel R. Lowery Retrievable umbrella sieve and method of use
US5941896A (en) 1997-09-08 1999-08-24 Montefiore Hospital And Medical Center Filter and method for trapping emboli during endovascular procedures
FR2768326B1 (en) 1997-09-18 1999-10-22 De Bearn Olivier Despalle TEMPORARY BLOOD FILTER
US6395014B1 (en) 1997-09-26 2002-05-28 John A. Macoviak Cerebral embolic protection assembly and associated methods
US6361545B1 (en) 1997-09-26 2002-03-26 Cardeon Corporation Perfusion filter catheter
US6066149A (en) * 1997-09-30 2000-05-23 Target Therapeutics, Inc. Mechanical clot treatment device with distal filter
US6174318B1 (en) * 1998-04-23 2001-01-16 Scimed Life Systems, Inc. Basket with one or more moveable legs
US6099534A (en) 1997-10-01 2000-08-08 Scimed Life Systems, Inc. Releasable basket
US6183482B1 (en) 1997-10-01 2001-02-06 Scimed Life Systems, Inc. Medical retrieval basket with legs shaped to enhance capture and reduce trauma
US6461370B1 (en) 1998-11-03 2002-10-08 C. R. Bard, Inc. Temporary vascular filter guide wire
US7491216B2 (en) * 1997-11-07 2009-02-17 Salviac Limited Filter element with retractable guidewire tip
IES81060B2 (en) 1997-11-07 2000-01-12 Salviac Ltd An embolic protection device
DE69839888D1 (en) 1997-11-12 2008-09-25 Genesis Technologies Llc DEVICE FOR REMOVING OCCLUSIONS IN BIOLOGICAL PASSES
US20040260333A1 (en) 1997-11-12 2004-12-23 Dubrul William R. Medical device and method
US6136015A (en) 1998-08-25 2000-10-24 Micrus Corporation Vasoocclusive coil
US6695864B2 (en) 1997-12-15 2004-02-24 Cardeon Corporation Method and apparatus for cerebral embolic protection
ATE454098T1 (en) 1998-02-10 2010-01-15 Artemis Medical Inc OCCLUSION, ANCHORING, CHIPING OR POWER CONTROL DEVICE
EP1054634A4 (en) 1998-02-10 2006-03-29 Artemis Medical Inc Entrapping apparatus and method for use
US6206868B1 (en) 1998-03-13 2001-03-27 Arteria Medical Science, Inc. Protective device and method against embolization during treatment of carotid artery disease
US6423032B2 (en) 1998-03-13 2002-07-23 Arteria Medical Science, Inc. Apparatus and methods for reducing embolization during treatment of carotid artery disease
US20050131453A1 (en) 1998-03-13 2005-06-16 Parodi Juan C. Apparatus and methods for reducing embolization during treatment of carotid artery disease
CN1295451A (en) 1998-04-02 2001-05-16 萨尔维亚克有限公司 Delivery catheter
IE980241A1 (en) 1998-04-02 1999-10-20 Salviac Ltd Delivery catheter with split sheath
US5944728A (en) 1998-04-23 1999-08-31 Boston Scientific Corporation Surgical retrieval basket with the ability to capture and release material
US6450989B2 (en) 1998-04-27 2002-09-17 Artemis Medical, Inc. Dilating and support apparatus with disease inhibitors and methods for use
US6007557A (en) 1998-04-29 1999-12-28 Embol-X, Inc. Adjustable blood filtration system
US6511492B1 (en) 1998-05-01 2003-01-28 Microvention, Inc. Embolectomy catheters and methods for treating stroke and other small vessel thromboembolic disorders
US6908474B2 (en) 1998-05-13 2005-06-21 Gore Enterprise Holdings, Inc. Apparatus and methods for reducing embolization during treatment of carotid artery disease
JP4741728B2 (en) 1998-06-04 2011-08-10 ニューヨーク・ユニバーシティ Intravascular thin film device and stroke treatment
IL124958A0 (en) 1998-06-16 1999-01-26 Yodfat Ofer Implantable blood filtering device
US6241746B1 (en) 1998-06-29 2001-06-05 Cordis Corporation Vascular filter convertible to a stent and method
NL1009551C2 (en) 1998-07-03 2000-01-07 Cordis Europ Vena cava filter with improvements for controlled ejection.
US6306163B1 (en) 1998-08-04 2001-10-23 Advanced Cardiovascular Systems, Inc. Assembly for collecting emboli and method of use
US6231588B1 (en) 1998-08-04 2001-05-15 Percusurge, Inc. Low profile catheter for angioplasty and occlusion
US6179860B1 (en) * 1998-08-19 2001-01-30 Artemis Medical, Inc. Target tissue localization device and method
US6328755B1 (en) 1998-09-24 2001-12-11 Scimed Life Systems, Inc. Filter delivery device
US6051014A (en) 1998-10-13 2000-04-18 Embol-X, Inc. Percutaneous filtration catheter for valve repair surgery and methods of use
US7044134B2 (en) 1999-11-08 2006-05-16 Ev3 Sunnyvale, Inc Method of implanting a device in the left atrial appendage
US7128073B1 (en) 1998-11-06 2006-10-31 Ev3 Endovascular, Inc. Method and device for left atrial appendage occlusion
US6083239A (en) 1998-11-24 2000-07-04 Embol-X, Inc. Compliant framework and methods of use
US6102932A (en) * 1998-12-15 2000-08-15 Micrus Corporation Intravascular device push wire delivery system
US6652554B1 (en) 1999-01-04 2003-11-25 Mark H. Wholey Instrument for thromboembolic protection
US6254609B1 (en) * 1999-01-11 2001-07-03 Scimed Life Systems, Inc. Self-expanding stent delivery system with two sheaths
US6896690B1 (en) 2000-01-27 2005-05-24 Viacor, Inc. Cardiac valve procedure methods and devices
AU2315500A (en) 1999-01-28 2000-08-18 Ansamed Limited Catheter with an expandable end portion
US7018401B1 (en) * 1999-02-01 2006-03-28 Board Of Regents, The University Of Texas System Woven intravascular devices and methods for making the same and apparatus for delivery of the same
US20020138094A1 (en) 1999-02-12 2002-09-26 Thomas Borillo Vascular filter system
US6991641B2 (en) * 1999-02-12 2006-01-31 Cordis Corporation Low profile vascular filter system
US6171327B1 (en) 1999-02-24 2001-01-09 Scimed Life Systems, Inc. Intravascular filter and method
US6355051B1 (en) 1999-03-04 2002-03-12 Bioguide Consulting, Inc. Guidewire filter device
US20020169474A1 (en) 1999-03-08 2002-11-14 Microvena Corporation Minimally invasive medical device deployment and retrieval system
US6632236B2 (en) 1999-03-12 2003-10-14 Arteria Medical Science, Inc. Catheter having radially expandable main body
US6245012B1 (en) 1999-03-19 2001-06-12 Nmt Medical, Inc. Free standing filter
US6893450B2 (en) 1999-03-26 2005-05-17 Cook Urological Incorporated Minimally-invasive medical retrieval device
US6743247B1 (en) 1999-04-01 2004-06-01 Scion Cardio-Vascular, Inc. Locking frame, filter and deployment system
US6277138B1 (en) 1999-08-17 2001-08-21 Scion Cardio-Vascular, Inc. Filter for embolic material mounted on expandable frame
US6537296B2 (en) 1999-04-01 2003-03-25 Scion Cardio-Vascular, Inc. Locking frame, filter and deployment system
US6277139B1 (en) 1999-04-01 2001-08-21 Scion Cardio-Vascular, Inc. Vascular protection and embolic material retriever
US7150756B2 (en) 1999-04-01 2006-12-19 Scion Cardio-Vascular, Inc Radiopaque locking frame, filter and flexible end
US6340465B1 (en) * 1999-04-12 2002-01-22 Edwards Lifesciences Corp. Lubricious coatings for medical devices
US6267776B1 (en) 1999-05-03 2001-07-31 O'connell Paul T. Vena cava filter and method for treating pulmonary embolism
WO2000067666A1 (en) 1999-05-07 2000-11-16 Salviac Limited Improved filter element for embolic protection device
EP1176923A1 (en) 1999-05-07 2002-02-06 Salviac Limited An embolic protection device
US20020058911A1 (en) 1999-05-07 2002-05-16 Paul Gilson Support frame for an embolic protection device
US6964672B2 (en) 1999-05-07 2005-11-15 Salviac Limited Support frame for an embolic protection device
WO2000067665A1 (en) 1999-05-07 2000-11-16 Salviac Limited Support frame for embolic protection device
US6918921B2 (en) 1999-05-07 2005-07-19 Salviac Limited Support frame for an embolic protection device
US7014647B2 (en) 1999-05-07 2006-03-21 Salviac Limited Support frame for an embolic protection device
US6585756B1 (en) 1999-05-14 2003-07-01 Ernst P. Strecker Implantable lumen prosthesis
US6176849B1 (en) * 1999-05-21 2001-01-23 Scimed Life Systems, Inc. Hydrophilic lubricity coating for medical devices comprising a hydrophobic top coat
FR2794653B1 (en) * 1999-06-14 2001-12-21 Sarl Aln KIT FOR THE REMOVAL OF A BLADDER VESSEL FILTER OF THE UMBRELLA TYPE
US6458139B1 (en) 1999-06-21 2002-10-01 Endovascular Technologies, Inc. Filter/emboli extractor for use in variable sized blood vessels
US6468291B2 (en) 1999-07-16 2002-10-22 Baff Llc Emboli filtration system having integral strut arrangement and methods of use
US6179859B1 (en) * 1999-07-16 2001-01-30 Baff Llc Emboli filtration system and methods of use
US20030150821A1 (en) 1999-07-16 2003-08-14 Bates Mark C. Emboli filtration system and methods of use
US6485507B1 (en) 1999-07-28 2002-11-26 Scimed Life Systems Multi-property nitinol by heat treatment
US6616679B1 (en) 1999-07-30 2003-09-09 Incept, Llc Rapid exchange vascular device for emboli and thrombus removal and methods of use
US7229462B2 (en) 1999-07-30 2007-06-12 Angioguard, Inc. Vascular filter system for carotid endarterectomy
EP1207933B1 (en) 1999-07-30 2011-05-11 Incept Llc Vascular filter having articulation region
US6620182B1 (en) 1999-07-30 2003-09-16 Incept Llc Vascular filter having articulation region and methods of use in the ascending aorta
US6214026B1 (en) 1999-07-30 2001-04-10 Incept Llc Delivery system for a vascular device with articulation region
US7306618B2 (en) 1999-07-30 2007-12-11 Incept Llc Vascular device for emboli and thrombi removal and methods of use
US6371970B1 (en) 1999-07-30 2002-04-16 Incept Llc Vascular filter having articulation region and methods of use in the ascending aorta
US7320697B2 (en) 1999-07-30 2008-01-22 Boston Scientific Scimed, Inc. One piece loop and coil
US6544279B1 (en) 2000-08-09 2003-04-08 Incept, Llc Vascular device for emboli, thrombus and foreign body removal and methods of use
US6589263B1 (en) 1999-07-30 2003-07-08 Incept Llc Vascular device having one or more articulation regions and methods of use
US6203561B1 (en) 1999-07-30 2001-03-20 Incept Llc Integrated vascular device having thrombectomy element and vascular filter and methods of use
US7229463B2 (en) 1999-07-30 2007-06-12 Angioguard, Inc. Vascular filter system for cardiopulmonary bypass
US6179861B1 (en) * 1999-07-30 2001-01-30 Incept Llc Vascular device having one or more articulation regions and methods of use
US6530939B1 (en) 1999-07-30 2003-03-11 Incept, Llc Vascular device having articulation region and methods of use
US6142987A (en) 1999-08-03 2000-11-07 Scimed Life Systems, Inc. Guided filter with support wire and methods of use
US6245087B1 (en) 1999-08-03 2001-06-12 Embol-X, Inc. Variable expansion frame system for deploying medical devices and methods of use
US6346116B1 (en) 1999-08-03 2002-02-12 Medtronic Ave, Inc. Distal protection device
US6235044B1 (en) 1999-08-04 2001-05-22 Scimed Life Systems, Inc. Percutaneous catheter and guidewire for filtering during ablation of mycardial or vascular tissue
US6168579B1 (en) * 1999-08-04 2001-01-02 Scimed Life Systems, Inc. Filter flush system and methods of use
US6273901B1 (en) 1999-08-10 2001-08-14 Scimed Life Systems, Inc. Thrombosis filter having a surface treatment
ATE410975T1 (en) 1999-08-27 2008-10-15 Ev3 Inc SLIDING VASCULAR FILTER
US6251122B1 (en) 1999-09-02 2001-06-26 Scimed Life Systems, Inc. Intravascular filter retrieval device and method
US6187025B1 (en) * 1999-09-09 2001-02-13 Noble-Met, Ltd. Vascular filter
DE29916162U1 (en) * 1999-09-14 2000-01-13 Cormedics Gmbh Vascular filter system
US6325815B1 (en) 1999-09-21 2001-12-04 Microvena Corporation Temporary vascular filter
US6939361B1 (en) 1999-09-22 2005-09-06 Nmt Medical, Inc. Guidewire for a free standing intervascular device having an integral stop mechanism
US6364895B1 (en) 1999-10-07 2002-04-02 Prodesco, Inc. Intraluminal filter
US6375670B1 (en) 1999-10-07 2002-04-23 Prodesco, Inc. Intraluminal filter
US6340364B2 (en) * 1999-10-22 2002-01-22 Nozomu Kanesaka Vascular filtering device
US6264672B1 (en) 1999-10-25 2001-07-24 Biopsy Sciences, Llc Emboli capturing device
US6425909B1 (en) 1999-11-04 2002-07-30 Concentric Medical, Inc. Methods and devices for filtering fluid flow through a body structure
US6171328B1 (en) * 1999-11-09 2001-01-09 Embol-X, Inc. Intravascular catheter filter with interlocking petal design and methods of use
US6371971B1 (en) 1999-11-15 2002-04-16 Scimed Life Systems, Inc. Guidewire filter and methods of use
WO2001035858A1 (en) 1999-11-18 2001-05-25 Advanced Cardiovascular Systems, Inc. Embolic protection system and method including an emboli-capturing catheter
US6331184B1 (en) * 1999-12-10 2001-12-18 Scimed Life Systems, Inc. Detachable covering for an implantable medical device
US6623450B1 (en) 1999-12-17 2003-09-23 Advanced Cardiovascular Systems, Inc. System for blocking the passage of emboli through a body vessel
US6443979B1 (en) 1999-12-20 2002-09-03 Advanced Cardiovascular Systems, Inc. Expandable stent delivery sheath and method of use
US6443971B1 (en) 1999-12-21 2002-09-03 Advanced Cardiovascular Systems, Inc. System for, and method of, blocking the passage of emboli through a vessel
US6402771B1 (en) 1999-12-23 2002-06-11 Guidant Endovascular Solutions Snare
US6660021B1 (en) 1999-12-23 2003-12-09 Advanced Cardiovascular Systems, Inc. Intravascular device and system
US6575997B1 (en) 1999-12-23 2003-06-10 Endovascular Technologies, Inc. Embolic basket
US6406471B1 (en) 1999-12-28 2002-06-18 Embol-X, Inc. Arterial filter with aspiration and methods of use
US6290710B1 (en) 1999-12-29 2001-09-18 Advanced Cardiovascular Systems, Inc. Embolic protection device
US6511503B1 (en) * 1999-12-30 2003-01-28 Advanced Cardiovascular Systems, Inc. Catheter apparatus for treating occluded vessels and filtering embolic debris and method of use
US6645220B1 (en) 1999-12-30 2003-11-11 Advanced Cardiovascular Systems, Inc. Embolic protection system and method including and embolic-capturing filter
US6702834B1 (en) 1999-12-30 2004-03-09 Advanced Cardiovascular Systems, Inc. Embolic protection devices
US6540722B1 (en) 1999-12-30 2003-04-01 Advanced Cardiovascular Systems, Inc. Embolic protection devices
US6383206B1 (en) 1999-12-30 2002-05-07 Advanced Cardiovascular Systems, Inc. Embolic protection system and method including filtering elements
US6290656B1 (en) 1999-12-30 2001-09-18 Advanced Cardiovascular Systems, Inc. Guide wire with damped force vibration mechanism
US6695813B1 (en) 1999-12-30 2004-02-24 Advanced Cardiovascular Systems, Inc. Embolic protection devices
US6361546B1 (en) 2000-01-13 2002-03-26 Endotex Interventional Systems, Inc. Deployable recoverable vascular filter and methods for use
US6443926B1 (en) 2000-02-01 2002-09-03 Harold D. Kletschka Embolic protection device having expandable trap
MXPA02007428A (en) 2000-02-01 2003-10-14 Harold D Kletschka Angioplasty device and method of making same.
US6517550B1 (en) * 2000-02-02 2003-02-11 Board Of Regents, The University Of Texas System Foreign body retrieval device
US6540767B1 (en) 2000-02-08 2003-04-01 Scimed Life Systems, Inc. Recoilable thrombosis filtering device and method
US6540768B1 (en) 2000-02-09 2003-04-01 Cordis Corporation Vascular filter system
US6863696B2 (en) 2000-02-16 2005-03-08 Viktoria Kantsevitcha Vascular prosthesis
US6629953B1 (en) 2000-02-18 2003-10-07 Fox Hollow Technologies, Inc. Methods and devices for removing material from a vascular site
WO2001062184A2 (en) 2000-02-23 2001-08-30 Boston Scientific Limited Intravascular filtering devices and methods
ES2282246T3 (en) 2000-03-10 2007-10-16 Anthony T. Don Michael VASCULAR EMBOLIA PREVENTION DEVICE USING FILTERS.
US6695865B2 (en) 2000-03-20 2004-02-24 Advanced Bio Prosthetic Surfaces, Ltd. Embolic protection device
US6485500B1 (en) 2000-03-21 2002-11-26 Advanced Cardiovascular Systems, Inc. Emboli protection system
US6514273B1 (en) * 2000-03-22 2003-02-04 Endovascular Technologies, Inc. Device for removal of thrombus through physiological adhesion
US6632241B1 (en) 2000-03-22 2003-10-14 Endovascular Technologies, Inc. Self-expanding, pseudo-braided intravascular device
US20040167567A1 (en) 2001-03-23 2004-08-26 Cano Gerald G. Method and apparatus for capturing objects beyond an operative site in medical procedures
GB2369575A (en) 2000-04-20 2002-06-05 Salviac Ltd An embolic protection system
US6706053B1 (en) 2000-04-28 2004-03-16 Advanced Cardiovascular Systems, Inc. Nitinol alloy design for sheath deployable and re-sheathable vascular devices
US6592616B1 (en) 2000-04-28 2003-07-15 Advanced Cardiovascular Systems, Inc. System and device for minimizing embolic risk during an interventional procedure
US6520978B1 (en) * 2000-05-15 2003-02-18 Intratherapeutics, Inc. Emboli filter
US6602271B2 (en) 2000-05-24 2003-08-05 Medtronic Ave, Inc. Collapsible blood filter with optimal braid geometry
US6645221B1 (en) 2000-05-30 2003-11-11 Zuli, Holdings Ltd. Active arterial embolization filter
US6939362B2 (en) 2001-11-27 2005-09-06 Advanced Cardiovascular Systems, Inc. Offset proximal cage for embolic filtering devices
US6565591B2 (en) 2000-06-23 2003-05-20 Salviac Limited Medical device
US6663650B2 (en) 2000-06-29 2003-12-16 Concentric Medical, Inc. Systems, methods and devices for removing obstructions from a blood vessel
US8298257B2 (en) 2000-06-29 2012-10-30 Concentric Medical, Inc. Systems, methods and devices for removing obstructions from a blood vessel
AU2001273088A1 (en) * 2000-06-30 2002-01-30 Viacor Incorporated Intravascular filter with debris entrapment mechanism
US6482222B1 (en) 2000-07-11 2002-11-19 Rafael Medical Technologies Inc. Intravascular filter
US6964670B1 (en) 2000-07-13 2005-11-15 Advanced Cardiovascular Systems, Inc. Embolic protection guide wire
US6575995B1 (en) 2000-07-14 2003-06-10 Advanced Cardiovascular Systems, Inc. Expandable cage embolic material filter system and method
US6656202B2 (en) 2000-07-14 2003-12-02 Advanced Cardiovascular Systems, Inc. Embolic protection systems
US6679902B1 (en) * 2000-07-19 2004-01-20 Advanced Cardiovascular Systems, Inc. Reduced profile delivery sheath for use in interventional procedures
US6740061B1 (en) 2000-07-28 2004-05-25 Ev3 Inc. Distal protection device
US6527746B1 (en) 2000-08-03 2003-03-04 Ev3, Inc. Back-loading catheter
WO2002011812A1 (en) 2000-08-04 2002-02-14 Duke University Temporary vascular filters and methods
US6394978B1 (en) 2000-08-09 2002-05-28 Advanced Cardiovascular Systems, Inc. Interventional procedure expandable balloon expansion enabling system and method
US6485501B1 (en) 2000-08-11 2002-11-26 Cordis Corporation Vascular filter system with guidewire and capture mechanism
US20020022860A1 (en) 2000-08-18 2002-02-21 Borillo Thomas E. Expandable implant devices for filtering blood flow from atrial appendages
US6558405B1 (en) 2000-08-29 2003-05-06 Advanced Cardiovascular Systems, Inc. Embolic filter
FR2813518B1 (en) 2000-09-04 2002-10-31 Claude Mialhe VASCULAR OCCLUSION DEVICE, APPARATUS AND METHOD OF USE
US6511496B1 (en) * 2000-09-12 2003-01-28 Advanced Cardiovascular Systems, Inc. Embolic protection device for use in interventional procedures
US6723108B1 (en) 2000-09-18 2004-04-20 Cordis Neurovascular, Inc Foam matrix embolization device
US6616681B2 (en) * 2000-10-05 2003-09-09 Scimed Life Systems, Inc. Filter delivery and retrieval device
US6537294B1 (en) 2000-10-17 2003-03-25 Advanced Cardiovascular Systems, Inc. Delivery systems for embolic filter devices
EP1326672A4 (en) 2000-10-18 2007-03-07 Nmt Medical Inc Over-the-wire interlock attachment/detachment mechanism
US6582447B1 (en) 2000-10-20 2003-06-24 Angiodynamics, Inc. Convertible blood clot filter
US6589265B1 (en) 2000-10-31 2003-07-08 Endovascular Technologies, Inc. Intrasaccular embolic device
US6616680B1 (en) 2000-11-01 2003-09-09 Joseph M. Thielen Distal protection and delivery system and method
US6602272B2 (en) 2000-11-02 2003-08-05 Advanced Cardiovascular Systems, Inc. Devices configured from heat shaped, strain hardened nickel-titanium
US6893451B2 (en) 2000-11-09 2005-05-17 Advanced Cardiovascular Systems, Inc. Apparatus for capturing objects beyond an operative site utilizing a capture device delivered on a medical guide wire
US6726703B2 (en) 2000-11-27 2004-04-27 Scimed Life Systems, Inc. Distal protection device and method
WO2002048248A2 (en) 2000-12-15 2002-06-20 Agrolinz Melamin Gmbh Modified inorganic particles
US6506203B1 (en) 2000-12-19 2003-01-14 Advanced Cardiovascular Systems, Inc. Low profile sheathless embolic protection system
US6582448B1 (en) 2000-12-21 2003-06-24 Advanced Cardiovascular Systems, Inc. Vessel occlusion device for embolic protection system
US6936059B2 (en) 2001-01-16 2005-08-30 Scimed Life Systems, Inc. Endovascular guidewire filter and methods of use
US7169165B2 (en) 2001-01-16 2007-01-30 Boston Scientific Scimed, Inc. Rapid exchange sheath for deployment of medical devices and methods of use
US6663651B2 (en) 2001-01-16 2003-12-16 Incept Llc Systems and methods for vascular filter retrieval
US6610077B1 (en) 2001-01-23 2003-08-26 Endovascular Technologies, Inc. Expandable emboli filter and thrombectomy device
US6689151B2 (en) 2001-01-25 2004-02-10 Scimed Life Systems, Inc. Variable wall thickness for delivery sheath housing
US20020128680A1 (en) 2001-01-25 2002-09-12 Pavlovic Jennifer L. Distal protection device with electrospun polymer fiber matrix
US6979343B2 (en) 2001-02-14 2005-12-27 Ev3 Inc. Rolled tip recovery catheter
US6506205B2 (en) * 2001-02-20 2003-01-14 Mark Goldberg Blood clot filtering system
US6840950B2 (en) 2001-02-20 2005-01-11 Scimed Life Systems, Inc. Low profile emboli capture device
US6569184B2 (en) 2001-02-27 2003-05-27 Advanced Cardiovascular Systems, Inc. Recovery system for retrieving an embolic protection device
US6974468B2 (en) 2001-02-28 2005-12-13 Scimed Life Systems, Inc. Filter retrieval catheter
US7226464B2 (en) 2001-03-01 2007-06-05 Scimed Life Systems, Inc. Intravascular filter retrieval device having an actuatable dilator tip
US20020123755A1 (en) 2001-03-01 2002-09-05 Scimed Life Systems, Inc. Embolic protection filter delivery sheath
US6562058B2 (en) 2001-03-02 2003-05-13 Jacques Seguin Intravascular filter system
US6537295B2 (en) 2001-03-06 2003-03-25 Scimed Life Systems, Inc. Wire and lock mechanism
US20020128679A1 (en) 2001-03-08 2002-09-12 Embol-X, Inc. Cerebral protection during carotid endarterectomy and methods of use
JP2005508201A (en) 2001-03-08 2005-03-31 アトリテック, インコーポレイテッド Atrial filter implant
US7214237B2 (en) 2001-03-12 2007-05-08 Don Michael T Anthony Vascular filter with improved strength and flexibility
US8298160B2 (en) 2001-03-16 2012-10-30 Ev3 Inc. Wire convertible from over-the-wire length to rapid exchange length
US6602269B2 (en) 2001-03-30 2003-08-05 Scimed Life Systems Embolic devices capable of in-situ reinforcement
US7101379B2 (en) 2001-04-02 2006-09-05 Acmi Corporation Retrieval basket for a surgical device and system and method for manufacturing same
US6428559B1 (en) 2001-04-03 2002-08-06 Cordis Corporation Removable, variable-diameter vascular filter system
US6706055B2 (en) 2001-04-03 2004-03-16 Medtronic Ave Inc. Guidewire apparatus for temporary distal embolic protection
US7044958B2 (en) 2001-04-03 2006-05-16 Medtronic Vascular, Inc. Temporary device for capturing embolic material
US6818006B2 (en) 2001-04-03 2004-11-16 Medtronic Vascular, Inc. Temporary intraluminal filter guidewire
US6866677B2 (en) 2001-04-03 2005-03-15 Medtronic Ave, Inc. Temporary intraluminal filter guidewire and methods of use
US20020161395A1 (en) 2001-04-03 2002-10-31 Nareak Douk Guide wire apparatus for prevention of distal atheroembolization
US6911036B2 (en) 2001-04-03 2005-06-28 Medtronic Vascular, Inc. Guidewire apparatus for temporary distal embolic protection
EP1379307B1 (en) 2001-04-17 2006-03-22 Salviac Limited A catheter
US6645223B2 (en) 2001-04-30 2003-11-11 Advanced Cardiovascular Systems, Inc. Deployment and recovery control systems for embolic protection devices
US6746469B2 (en) 2001-04-30 2004-06-08 Advanced Cardiovascular Systems, Inc. Balloon actuated apparatus having multiple embolic filters, and method of use
US6436121B1 (en) 2001-04-30 2002-08-20 Paul H. Blom Removable blood filter
US6814739B2 (en) 2001-05-18 2004-11-09 U.S. Endoscopy Group, Inc. Retrieval device
US6635070B2 (en) 2001-05-21 2003-10-21 Bacchus Vascular, Inc. Apparatus and methods for capturing particulate material within blood vessels
US6929652B1 (en) 2001-06-01 2005-08-16 Advanced Cardiovascular Systems, Inc. Delivery and recovery systems having steerability and rapid exchange operating modes for embolic protection systems
US20020188314A1 (en) 2001-06-07 2002-12-12 Microvena Corporation Radiopaque distal embolic protection device
US6596011B2 (en) 2001-06-12 2003-07-22 Cordis Corporation Emboli extraction catheter and vascular filter system
US6551341B2 (en) 2001-06-14 2003-04-22 Advanced Cardiovascular Systems, Inc. Devices configured from strain hardened Ni Ti tubing
JP4294470B2 (en) 2001-06-14 2009-07-15 クック インコーポレイテッド Intravascular filter
US6783538B2 (en) 2001-06-18 2004-08-31 Rex Medical, L.P Removable vein filter
US6623506B2 (en) 2001-06-18 2003-09-23 Rex Medical, L.P Vein filter
US6793665B2 (en) 2001-06-18 2004-09-21 Rex Medical, L.P. Multiple access vein filter
IL159572A0 (en) 2001-06-28 2004-06-01 Lithotech Medical Ltd Foreign body retrieval device
US7678128B2 (en) * 2001-06-29 2010-03-16 Advanced Cardiovascular Systems, Inc. Delivery and recovery sheaths for medical devices
US6575996B1 (en) 2001-06-29 2003-06-10 Advanced Cardiovascular Systems, Inc. Filter device for embolic protection system
US6599307B1 (en) 2001-06-29 2003-07-29 Advanced Cardiovascular Systems, Inc. Filter device for embolic protection systems
US7338510B2 (en) * 2001-06-29 2008-03-04 Advanced Cardiovascular Systems, Inc. Variable thickness embolic filtering devices and method of manufacturing the same
US6878153B2 (en) * 2001-07-02 2005-04-12 Rubicon Medical, Inc. Methods, systems, and devices for providing embolic protection and removing embolic material
US6951570B2 (en) * 2001-07-02 2005-10-04 Rubicon Medical, Inc. Methods, systems, and devices for deploying a filter from a filter device
JP4567918B2 (en) 2001-07-02 2010-10-27 テルモ株式会社 Intravascular foreign matter removal wire and medical device
US6962598B2 (en) 2001-07-02 2005-11-08 Rubicon Medical, Inc. Methods, systems, and devices for providing embolic protection
US6997939B2 (en) * 2001-07-02 2006-02-14 Rubicon Medical, Inc. Methods, systems, and devices for deploying an embolic protection filter
ES2264468T3 (en) * 2001-07-13 2007-01-01 B. Braun Medical Sas VASCULAR PROTECTION SYSTEM AND ANGIOPLASTIA APPARATUS EQUIPPED.
US7011671B2 (en) 2001-07-18 2006-03-14 Atritech, Inc. Cardiac implant device tether system and method
US6656203B2 (en) * 2001-07-18 2003-12-02 Cordis Corporation Integral vascular filter system
US6533800B1 (en) 2001-07-25 2003-03-18 Coaxia, Inc. Devices and methods for preventing distal embolization using flow reversal in arteries having collateral blood flow
US20030032941A1 (en) * 2001-08-13 2003-02-13 Boyle William J. Convertible delivery systems for medical devices
US6902540B2 (en) 2001-08-22 2005-06-07 Gerald Dorros Apparatus and methods for treating stroke and controlling cerebral flow characteristics
US6652557B1 (en) 2001-08-29 2003-11-25 Macdonald Kenneth A. Mechanism for capturing debris generated during vascular procedures
US6638294B1 (en) 2001-08-30 2003-10-28 Advanced Cardiovascular Systems, Inc. Self furling umbrella frame for carotid filter
US6656351B2 (en) 2001-08-31 2003-12-02 Advanced Cardiovascular Systems, Inc. Embolic protection devices one way porous membrane
US6592606B2 (en) 2001-08-31 2003-07-15 Advanced Cardiovascular Systems, Inc. Hinged short cage for an embolic protection device
US7097651B2 (en) 2001-09-06 2006-08-29 Advanced Cardiovascular Systems, Inc. Embolic protection basket
US6616682B2 (en) 2001-09-19 2003-09-09 Jomed Gmbh Methods and apparatus for distal protection during a medical procedure
US6878151B2 (en) 2001-09-27 2005-04-12 Scimed Life Systems, Inc. Medical retrieval device
US20030060843A1 (en) 2001-09-27 2003-03-27 Don Boucher Vascular filter system with encapsulated filter
US8262689B2 (en) 2001-09-28 2012-09-11 Advanced Cardiovascular Systems, Inc. Embolic filtering devices
US6755847B2 (en) 2001-10-05 2004-06-29 Scimed Life Systems, Inc. Emboli capturing device and method of manufacture therefor
US20030069597A1 (en) 2001-10-10 2003-04-10 Scimed Life Systems, Inc. Loading tool
US20030078614A1 (en) 2001-10-18 2003-04-24 Amr Salahieh Vascular embolic filter devices and methods of use therefor
US6887257B2 (en) 2001-10-19 2005-05-03 Incept Llc Vascular embolic filter exchange devices and methods of use thereof
US20030083692A1 (en) 2001-10-29 2003-05-01 Scimed Life Systems, Inc. Distal protection device and method of use thereof
US6790219B1 (en) 2001-11-06 2004-09-14 Edwards Lifesciences Corporation Filter with integrated obturator tip and methods of use
US20050021075A1 (en) * 2002-12-30 2005-01-27 Bonnette Michael J. Guidewire having deployable sheathless protective filter
US20030109824A1 (en) 2001-11-07 2003-06-12 Microvena Corporation Distal protection device with local drug delivery to maintain patency
US6890340B2 (en) 2001-11-29 2005-05-10 Medtronic Vascular, Inc. Apparatus for temporary intraluminal protection
US6837898B2 (en) * 2001-11-30 2005-01-04 Advanced Cardiovascular Systems, Inc. Intraluminal delivery system for an attachable treatment device
CA2759746C (en) 2001-12-05 2018-05-22 Smt Research And Development Ltd. Endovascular device for entrapment of particulate matter and method for use
US7153320B2 (en) 2001-12-13 2006-12-26 Scimed Life Systems, Inc. Hydraulic controlled retractable tip filter retrieval catheter
US6748255B2 (en) 2001-12-14 2004-06-08 Biosense Webster, Inc. Basket catheter with multiple location sensors
US6741878B2 (en) 2001-12-14 2004-05-25 Biosense Webster, Inc. Basket catheter with improved expansion mechanism
US6793666B2 (en) 2001-12-18 2004-09-21 Scimed Life Systems, Inc. Distal protection mechanically attached filter cartridge
US7241304B2 (en) 2001-12-21 2007-07-10 Advanced Cardiovascular Systems, Inc. Flexible and conformable embolic filtering devices
EP1455681B1 (en) 2001-12-21 2014-09-17 Salviac Limited A support frame for an embolic protection device
US6958074B2 (en) 2002-01-07 2005-10-25 Cordis Corporation Releasable and retrievable vascular filter system
US8647359B2 (en) 2002-01-10 2014-02-11 Boston Scientific Scimed, Inc. Distal protection filter
US6932830B2 (en) 2002-01-10 2005-08-23 Scimed Life Systems, Inc. Disc shaped filter
US20030135162A1 (en) 2002-01-17 2003-07-17 Scimed Life Systems, Inc. Delivery and retrieval manifold for a distal protection filter
CA2474324C (en) 2002-01-25 2011-09-20 Atritech, Inc. Atrial appendage blood filtration systems
US20030144686A1 (en) 2002-01-30 2003-07-31 Embol-X, Inc. Distal filtration devices and methods of use during aortic procedures
US7344549B2 (en) 2002-01-31 2008-03-18 Advanced Cardiovascular Systems, Inc. Expandable cages for embolic filtering devices
US6953471B1 (en) 2002-02-07 2005-10-11 Edwards Lifesciences Corporation Cannula with flexible remote cable filter deployment
US6997938B2 (en) 2002-02-12 2006-02-14 Scimed Life Systems, Inc. Embolic protection device
US20030158574A1 (en) 2002-02-15 2003-08-21 Esch Brady D. Flow-through aortic flow divider for cerebral and coronary embolic protection
US7004964B2 (en) 2002-02-22 2006-02-28 Scimed Life Systems, Inc. Apparatus and method for deployment of an endoluminal device
US7118539B2 (en) 2002-02-26 2006-10-10 Scimed Life Systems, Inc. Articulating guide wire for embolic protection and methods of use
AU2003209966A1 (en) 2002-03-05 2003-09-16 Salviac Limited An embolic protection system
US7192434B2 (en) 2002-03-08 2007-03-20 Ev3 Inc. Vascular protection devices and methods of use
US6773448B2 (en) * 2002-03-08 2004-08-10 Ev3 Inc. Distal protection devices having controllable wire motion
US20030176886A1 (en) 2002-03-12 2003-09-18 Wholey Mark H. Vascular catheter with expanded distal tip for receiving a thromboembolic protection device and method of use
US20030176884A1 (en) 2002-03-12 2003-09-18 Marwane Berrada Everted filter device
US7029440B2 (en) 2002-03-13 2006-04-18 Scimed Life Systems, Inc. Distal protection filter and method of manufacture
US20030187495A1 (en) 2002-04-01 2003-10-02 Cully Edward H. Endoluminal devices, embolic filters, methods of manufacture and use
US20030191493A1 (en) 2002-04-05 2003-10-09 Epstein Gordon H. Device for clot retrieval and distal protection
US20030199819A1 (en) 2002-04-17 2003-10-23 Beck Robert C. Filter wire system
US20030204168A1 (en) 2002-04-30 2003-10-30 Gjalt Bosma Coated vascular devices
US7060082B2 (en) 2002-05-06 2006-06-13 Scimed Life Systems, Inc. Perfusion guidewire in combination with a distal filter
US8070769B2 (en) 2002-05-06 2011-12-06 Boston Scientific Scimed, Inc. Inverted embolic protection filter
US20030229374A1 (en) 2002-05-10 2003-12-11 Salviac Limited Embolic protection system
AU2003237570A1 (en) * 2002-05-13 2003-11-11 Salviac Limited Catheter system with procedural catheter and embolic proctection system
US7585309B2 (en) 2002-05-16 2009-09-08 Boston Scientific Scimed, Inc. Aortic filter
US7001406B2 (en) 2002-05-23 2006-02-21 Scimed Life Systems Inc. Cartridge embolic protection filter and methods of use
US7959584B2 (en) 2002-05-29 2011-06-14 Boston Scientific Scimed, Inc. Dedicated distal protection guidewires
US7326224B2 (en) 2002-06-11 2008-02-05 Boston Scientific Scimed, Inc. Shaft and wire lock
US7717934B2 (en) 2002-06-14 2010-05-18 Ev3 Inc. Rapid exchange catheters usable with embolic protection devices
US6887258B2 (en) 2002-06-26 2005-05-03 Advanced Cardiovascular Systems, Inc. Embolic filtering devices for bifurcated vessels
US7172614B2 (en) * 2002-06-27 2007-02-06 Advanced Cardiovascular Systems, Inc. Support structures for embolic filtering devices
US6696666B2 (en) 2002-07-03 2004-02-24 Scimed Life Systems, Inc. Tubular cutting process and system
US6969402B2 (en) 2002-07-26 2005-11-29 Syntheon, Llc Helical stent having flexible transition zone
US7303575B2 (en) 2002-08-01 2007-12-04 Lumen Biomedical, Inc. Embolism protection devices
US6969395B2 (en) 2002-08-07 2005-11-29 Boston Scientific Scimed, Inc. Electroactive polymer actuated medical devices
US7115138B2 (en) 2002-09-04 2006-10-03 Boston Scientific Scimed, Inc. Sheath tip
US7174636B2 (en) 2002-09-04 2007-02-13 Scimed Life Systems, Inc. Method of making an embolic filter
US7056328B2 (en) 2002-09-18 2006-06-06 Arnott Richard J Apparatus for capturing objects beyond an operative site utilizing a capture device delivered on a medical guide wire
US7252675B2 (en) 2002-09-30 2007-08-07 Advanced Cardiovascular, Inc. Embolic filtering devices
US7331973B2 (en) 2002-09-30 2008-02-19 Avdanced Cardiovascular Systems, Inc. Guide wire with embolic filtering attachment
US20040093011A1 (en) 2002-10-01 2004-05-13 Scimed Life Systems, Inc. Embolic protection device with lesion length assessment markers
US7998163B2 (en) 2002-10-03 2011-08-16 Boston Scientific Scimed, Inc. Expandable retrieval device
AU2003300038A1 (en) 2002-10-11 2004-05-04 Scimed Life Systems, Inc. Embolic entrapment sheath
US20040093012A1 (en) 2002-10-17 2004-05-13 Cully Edward H. Embolic filter frame having looped support strut elements
WO2004039287A2 (en) 2002-10-29 2004-05-13 Peacock James C Iii Embolic filter device and related systems and methods
US20040088000A1 (en) 2002-10-31 2004-05-06 Muller Paul F. Single-wire expandable cages for embolic filtering devices
US6989021B2 (en) * 2002-10-31 2006-01-24 Cordis Corporation Retrievable medical filter
US20040098022A1 (en) 2002-11-14 2004-05-20 Barone David D. Intraluminal catheter with hydraulically collapsible self-expanding protection device
US20040111111A1 (en) 2002-12-10 2004-06-10 Scimed Life Systems, Inc. Intravascular filter membrane with shape memory
US7128752B2 (en) 2002-12-23 2006-10-31 Syntheon, Llc Emboli and thrombi filter device and method of using the same
US7625389B2 (en) 2002-12-30 2009-12-01 Boston Scientific Scimed, Inc. Embolic protection device
US20040138693A1 (en) 2003-01-14 2004-07-15 Scimed Life Systems, Inc. Snare retrievable embolic protection filter with guidewire stopper
US20040138694A1 (en) 2003-01-15 2004-07-15 Scimed Life Systems, Inc. Intravascular filtering membrane and method of making an embolic protection filter device
US7422595B2 (en) 2003-01-17 2008-09-09 Scion Cardio-Vascular, Inc. Proximal actuator for medical device
US20040147955A1 (en) 2003-01-28 2004-07-29 Scimed Life Systems, Inc. Embolic protection filter having an improved filter frame
US7220271B2 (en) 2003-01-30 2007-05-22 Ev3 Inc. Embolic filters having multiple layers and controlled pore size
US20040153119A1 (en) 2003-01-30 2004-08-05 Kusleika Richard S. Embolic filters with a distal loop or no loop
US7163549B2 (en) 2003-02-11 2007-01-16 Boston Scientific Scimed Inc. Filter membrane manufacturing method
JP2004261235A (en) 2003-02-20 2004-09-24 Kaneka Medix Corp Medical wire device
US7740644B2 (en) 2003-02-24 2010-06-22 Boston Scientific Scimed, Inc. Embolic protection filtering device that can be adapted to be advanced over a guidewire
US7137991B2 (en) 2003-02-24 2006-11-21 Scimed Life Systems, Inc. Multi-wire embolic protection filtering device
US20040167566A1 (en) 2003-02-24 2004-08-26 Scimed Life Systems, Inc. Apparatus for anchoring an intravascular device along a guidewire
US8591540B2 (en) * 2003-02-27 2013-11-26 Abbott Cardiovascular Systems Inc. Embolic filtering devices
US20040172055A1 (en) 2003-02-27 2004-09-02 Huter Scott J. Embolic filtering devices
US7909862B2 (en) 2003-03-19 2011-03-22 Cook Medical Technologies Llc Delivery systems and methods for deploying expandable intraluminal medical devices
US6960370B2 (en) 2003-03-27 2005-11-01 Scimed Life Systems, Inc. Methods of forming medical devices
US20040193208A1 (en) 2003-03-27 2004-09-30 Scimed Life Systems, Inc. Radiopaque embolic protection filter membrane
WO2004087018A2 (en) 2003-03-28 2004-10-14 Ev3 Inc. Double ended intravascular medical device
US6902572B2 (en) 2003-04-02 2005-06-07 Scimed Life Systems, Inc. Anchoring mechanisms for intravascular devices
US20040199199A1 (en) 2003-04-02 2004-10-07 Scimed Life Systems, Inc. Filter and method of making a filter
US20040204737A1 (en) 2003-04-11 2004-10-14 Scimed Life Systems, Inc. Embolic filter loop fabricated from composite material
US7591832B2 (en) 2003-04-24 2009-09-22 Medtronic, Inc. Expandable guide sheath and apparatus with distal protection and methods for use
US7604649B2 (en) * 2003-04-29 2009-10-20 Rex Medical, L.P. Distal protection device
US7331976B2 (en) 2003-04-29 2008-02-19 Rex Medical, L.P. Distal protection device
EP1472996B1 (en) * 2003-04-30 2009-09-30 Medtronic Vascular, Inc. Percutaneously delivered temporary valve
US7942892B2 (en) 2003-05-01 2011-05-17 Abbott Cardiovascular Systems Inc. Radiopaque nitinol embolic protection frame
US6969396B2 (en) 2003-05-07 2005-11-29 Scimed Life Systems, Inc. Filter membrane with increased surface area
US20040249409A1 (en) 2003-06-09 2004-12-09 Scimed Life Systems, Inc. Reinforced filter membrane
US7537600B2 (en) 2003-06-12 2009-05-26 Boston Scientific Scimed, Inc. Valved embolic protection filter
US20050004594A1 (en) * 2003-07-02 2005-01-06 Jeffrey Nool Devices and methods for aspirating from filters
US8337519B2 (en) * 2003-07-10 2012-12-25 Boston Scientific Scimed, Inc. Embolic protection filtering device
US8535344B2 (en) 2003-09-12 2013-09-17 Rubicon Medical, Inc. Methods, systems, and devices for providing embolic protection and removing embolic material
US20050070953A1 (en) 2003-09-18 2005-03-31 Riley James W. Medical device with flexible distal end loop and related methods of use
US7604650B2 (en) 2003-10-06 2009-10-20 3F Therapeutics, Inc. Method and assembly for distal embolic protection
US6994718B2 (en) 2003-10-29 2006-02-07 Medtronic Vascular, Inc. Distal protection device for filtering and occlusion
US8048103B2 (en) 2003-11-06 2011-11-01 Boston Scientific Scimed, Inc. Flattened tip filter wire design
US6972025B2 (en) 2003-11-18 2005-12-06 Scimed Life Systems, Inc. Intravascular filter with bioabsorbable centering element
US7354445B2 (en) 2003-12-15 2008-04-08 Medtronic Vascular Inc. Embolic containment system with asymmetric frictional control
US20050149110A1 (en) 2003-12-16 2005-07-07 Wholey Mark H. Vascular catheter with an expandable section and a distal tip for delivering a thromboembolic protection device and method of use
US20050159772A1 (en) 2004-01-20 2005-07-21 Scimed Life Systems, Inc. Sheath for use with an embolic protection filtering device
US20050159773A1 (en) 2004-01-20 2005-07-21 Scimed Life Systems, Inc. Expandable retrieval device with dilator tip
US8092483B2 (en) 2004-03-06 2012-01-10 Medtronic, Inc. Steerable device having a corewire within a tube and combination with a functional medical component
US7473265B2 (en) 2004-03-15 2009-01-06 Boston Scientific Scimed, Inc. Filter media and methods of manufacture
US7232462B2 (en) 2004-03-31 2007-06-19 Cook Incorporated Self centering delivery catheter
US8403976B2 (en) 2004-04-08 2013-03-26 Contego Medical Llc Percutaneous transluminal angioplasty device with integral embolic filter
US20050240215A1 (en) 2004-04-21 2005-10-27 Scimed Life Systems, Inc. Magnetic embolic protection device and method
WO2006055052A2 (en) * 2004-07-19 2006-05-26 Michael Gertner Methods and devices for chronic embolic protection
US20060020286A1 (en) * 2004-07-22 2006-01-26 Volker Niermann Device for filtering blood in a vessel with helical elements
US20060020285A1 (en) * 2004-07-22 2006-01-26 Volker Niermann Method for filtering blood in a vessel with helical elements
US7918872B2 (en) 2004-07-30 2011-04-05 Codman & Shurtleff, Inc. Embolic device delivery system with retractable partially coiled-fiber release
ATE520369T1 (en) 2004-09-17 2011-09-15 Nitinol Dev Corp SHAPE MEMORY THIN FILM EMBOLIC PROTECTION DEVICE
US8038696B2 (en) 2004-12-06 2011-10-18 Boston Scientific Scimed, Inc. Sheath for use with an embolic protection filter
US20060129181A1 (en) 2004-12-13 2006-06-15 Callol Joseph R Retrieval device with retractable dilator tip
US20060149313A1 (en) 2004-12-30 2006-07-06 Edward Arguello Distal protection apparatus with improved wall apposition
US20060149312A1 (en) 2004-12-30 2006-07-06 Edward Arguello Distal protection device with improved wall apposition
US7527637B2 (en) 2005-01-07 2009-05-05 Medtronic Vascular Inc. Distal protection device for filtering and occlusion
US20060206139A1 (en) 2005-01-19 2006-09-14 Tekulve Kurt J Vascular occlusion device
US20060184194A1 (en) 2005-02-15 2006-08-17 Cook Incorporated Embolic protection device
WO2006089178A2 (en) 2005-02-18 2006-08-24 Ev3 Inc. Rapid exchange catheters and embolic protection devices

Patent Citations (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5720754A (en) * 1989-08-16 1998-02-24 Medtronic, Inc. Device or apparatus for manipulating matter
US5904690A (en) * 1989-08-16 1999-05-18 Medtronic, Inc. Device or apparatus for manipulating matter
US5601572A (en) * 1989-08-16 1997-02-11 Raychem Corporation Device or apparatus for manipulating matter having a elastic ring clip
US5820628A (en) * 1989-08-16 1998-10-13 Medtronic, Inc. Device or apparatus for manipulating matter
US5509923A (en) * 1989-08-16 1996-04-23 Raychem Corporation Device for dissecting, grasping, or cutting an object
US5695518A (en) * 1990-12-28 1997-12-09 Laerum; Frode Filtering device for preventing embolism and/or distension of blood vessel walls
US5720764A (en) * 1994-06-11 1998-02-24 Naderlinger; Eduard Vena cava thrombus filter
US5549626A (en) * 1994-12-23 1996-08-27 New York Society For The Ruptured And Crippled Maintaining The Hospital For Special Surgery Vena caval filter
US6168603B1 (en) * 1995-02-02 2001-01-02 Boston Scientific Corporation Surgical extractor
US5681347A (en) * 1995-05-23 1997-10-28 Boston Scientific Corporation Vena cava filter delivery system
US5792156A (en) * 1995-06-27 1998-08-11 Laboratoire Perouse Implant Instrument for vascular surgery and its use
US5895398A (en) * 1996-02-02 1999-04-20 The Regents Of The University Of California Method of using a clot capture coil
US5810874A (en) * 1996-02-22 1998-09-22 Cordis Corporation Temporary filter catheter
US5902263A (en) * 1997-02-12 1999-05-11 Prolifix Medical, Inc. Apparatus and method for removing stenotic material from stents
US6053932A (en) * 1997-03-06 2000-04-25 Scimed Life Systems, Inc. Distal protection device
US6443972B1 (en) * 1997-11-19 2002-09-03 Cordis Europa N.V. Vascular filter
US6551342B1 (en) * 2001-08-24 2003-04-22 Endovascular Technologies, Inc. Embolic filter

Cited By (108)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8142442B2 (en) 1999-12-23 2012-03-27 Abbott Laboratories Snare
US8137377B2 (en) 1999-12-23 2012-03-20 Abbott Laboratories Embolic basket
US7780694B2 (en) 1999-12-23 2010-08-24 Advanced Cardiovascular Systems, Inc. Intravascular device and system
US7918820B2 (en) 1999-12-30 2011-04-05 Advanced Cardiovascular Systems, Inc. Device for, and method of, blocking emboli in vessels such as blood arteries
US8845583B2 (en) 1999-12-30 2014-09-30 Abbott Cardiovascular Systems Inc. Embolic protection devices
US8177791B2 (en) 2000-07-13 2012-05-15 Abbott Cardiovascular Systems Inc. Embolic protection guide wire
US7662166B2 (en) 2000-12-19 2010-02-16 Advanced Cardiocascular Systems, Inc. Sheathless embolic protection system
US7931666B2 (en) 2000-12-19 2011-04-26 Advanced Cardiovascular Systems, Inc. Sheathless embolic protection system
US8016854B2 (en) 2001-06-29 2011-09-13 Abbott Cardiovascular Systems Inc. Variable thickness embolic filtering devices and methods of manufacturing the same
US7959646B2 (en) 2001-06-29 2011-06-14 Abbott Cardiovascular Systems Inc. Filter device for embolic protection systems
US20090019073A1 (en) * 2001-08-29 2009-01-15 Takahi Itoh System and method for transcoding digital content
US7959647B2 (en) 2001-08-30 2011-06-14 Abbott Cardiovascular Systems Inc. Self furling umbrella frame for carotid filter
US7842064B2 (en) 2001-08-31 2010-11-30 Advanced Cardiovascular Systems, Inc. Hinged short cage for an embolic protection device
US8262689B2 (en) 2001-09-28 2012-09-11 Advanced Cardiovascular Systems, Inc. Embolic filtering devices
US20050075663A1 (en) * 2001-11-27 2005-04-07 Boyle William J. Offset proximal cage for embolic filtering devices
US20030120303A1 (en) * 2001-12-21 2003-06-26 Boyle William J. Flexible and conformable embolic filtering devices
US7972356B2 (en) 2001-12-21 2011-07-05 Abbott Cardiovascular Systems, Inc. Flexible and conformable embolic filtering devices
US7815660B2 (en) 2002-09-30 2010-10-19 Advanced Cardivascular Systems, Inc. Guide wire with embolic filtering attachment
US7976560B2 (en) 2002-09-30 2011-07-12 Abbott Cardiovascular Systems Inc. Embolic filtering devices
US8029530B2 (en) 2002-09-30 2011-10-04 Abbott Cardiovascular Systems Inc. Guide wire with embolic filtering attachment
US7678131B2 (en) 2002-10-31 2010-03-16 Advanced Cardiovascular Systems, Inc. Single-wire expandable cages for embolic filtering devices
US8591540B2 (en) 2003-02-27 2013-11-26 Abbott Cardiovascular Systems Inc. Embolic filtering devices
US7892251B1 (en) 2003-11-12 2011-02-22 Advanced Cardiovascular Systems, Inc. Component for delivering and locking a medical device to a guide wire
US7678129B1 (en) 2004-03-19 2010-03-16 Advanced Cardiovascular Systems, Inc. Locking component for an embolic filter assembly
US8308753B2 (en) 2004-03-19 2012-11-13 Advanced Cardiovascular Systems, Inc. Locking component for an embolic filter assembly
US7879065B2 (en) 2004-03-19 2011-02-01 Advanced Cardiovascular Systems, Inc. Locking component for an embolic filter assembly
US9259305B2 (en) 2005-03-31 2016-02-16 Abbott Cardiovascular Systems Inc. Guide wire locking mechanism for rapid exchange and other catheter systems
US9801650B2 (en) 2006-12-22 2017-10-31 The Spectranetics Corporation Tissue separating systems and methods
US9289226B2 (en) 2006-12-22 2016-03-22 The Spectranetics Corporation Retractable separating systems and methods
US9808275B2 (en) 2006-12-22 2017-11-07 The Spectranetics Corporation Retractable separating systems and methods
US10537354B2 (en) 2006-12-22 2020-01-21 The Spectranetics Corporation Retractable separating systems and methods
US10869687B2 (en) 2006-12-22 2020-12-22 Spectranetics Llc Tissue separating systems and methods
US9028520B2 (en) 2006-12-22 2015-05-12 The Spectranetics Corporation Tissue separating systems and methods
US8961551B2 (en) 2006-12-22 2015-02-24 The Spectranetics Corporation Retractable separating systems and methods
US8216209B2 (en) 2007-05-31 2012-07-10 Abbott Cardiovascular Systems Inc. Method and apparatus for delivering an agent to a kidney
US7867273B2 (en) 2007-06-27 2011-01-11 Abbott Laboratories Endoprostheses for peripheral arteries and other body vessels
US9387098B2 (en) 2007-10-17 2016-07-12 Covidien Lp Revascularization devices
US9220522B2 (en) 2007-10-17 2015-12-29 Covidien Lp Embolus removal systems with baskets
US8574262B2 (en) * 2007-10-17 2013-11-05 Covidien Lp Revascularization devices
US11786254B2 (en) 2007-10-17 2023-10-17 Covidien Lp Methods of managing neurovascular obstructions
US11337714B2 (en) 2007-10-17 2022-05-24 Covidien Lp Restoring blood flow and clot removal during acute ischemic stroke
US9320532B2 (en) 2007-10-17 2016-04-26 Covidien Lp Expandable tip assembly for thrombus management
US10835257B2 (en) 2007-10-17 2020-11-17 Covidien Lp Methods of managing neurovascular obstructions
US8945172B2 (en) 2007-10-17 2015-02-03 Covidien Lp Devices for restoring blood flow and clot removal during acute ischemic stroke
US8945143B2 (en) 2007-10-17 2015-02-03 Covidien Lp Expandable tip assembly for thrombus management
US8197493B2 (en) 2007-10-17 2012-06-12 Mindframe, Inc. Method for providing progressive therapy for thrombus management
US8585713B2 (en) 2007-10-17 2013-11-19 Covidien Lp Expandable tip assembly for thrombus management
US10413310B2 (en) 2007-10-17 2019-09-17 Covidien Lp Restoring blood flow and clot removal during acute ischemic stroke
US9198687B2 (en) 2007-10-17 2015-12-01 Covidien Lp Acute stroke revascularization/recanalization systems processes and products thereby
US8070791B2 (en) 2007-10-17 2011-12-06 Mindframe, Inc. Multiple layer embolus removal
US20120022576A1 (en) * 2007-10-17 2012-01-26 Mindframe, Inc. Revascularization devices
US10123803B2 (en) 2007-10-17 2018-11-13 Covidien Lp Methods of managing neurovascular obstructions
US10016211B2 (en) 2007-10-17 2018-07-10 Covidien Lp Expandable tip assembly for thrombus management
US8066757B2 (en) 2007-10-17 2011-11-29 Mindframe, Inc. Blood flow restoration and thrombus management methods
US8926680B2 (en) 2007-11-12 2015-01-06 Covidien Lp Aneurysm neck bridging processes with revascularization systems methods and products thereby
US10456151B2 (en) 2008-02-22 2019-10-29 Covidien Lp Methods and apparatus for flow restoration
US8940003B2 (en) 2008-02-22 2015-01-27 Covidien Lp Methods and apparatus for flow restoration
US8679142B2 (en) 2008-02-22 2014-03-25 Covidien Lp Methods and apparatus for flow restoration
US9161766B2 (en) 2008-02-22 2015-10-20 Covidien Lp Methods and apparatus for flow restoration
US11529156B2 (en) 2008-02-22 2022-12-20 Covidien Lp Methods and apparatus for flow restoration
US8545514B2 (en) 2008-04-11 2013-10-01 Covidien Lp Monorail neuro-microcatheter for delivery of medical devices to treat stroke, processes and products thereby
US8088140B2 (en) 2008-05-19 2012-01-03 Mindframe, Inc. Blood flow restorative and embolus removal methods
US20100022951A1 (en) * 2008-05-19 2010-01-28 Luce, Forward, Hamilton 7 Scripps, Llp Detachable hub/luer device and processes
US10722255B2 (en) 2008-12-23 2020-07-28 Covidien Lp Systems and methods for removing obstructive matter from body lumens and treating vascular defects
US20110184454A1 (en) * 2010-01-27 2011-07-28 Penumbra, Inc. Embolic implants
WO2011094226A1 (en) * 2010-01-27 2011-08-04 Penumbra, Inc. Embolic implants
US20120123466A1 (en) * 2010-11-12 2012-05-17 Stryker Nv Operations, Ltd. Axially variable radial pressure cages for clot capture
US9763692B2 (en) 2012-09-14 2017-09-19 The Spectranetics Corporation Tissue slitting methods and systems
US9413896B2 (en) 2012-09-14 2016-08-09 The Spectranetics Corporation Tissue slitting methods and systems
US10368900B2 (en) 2012-09-14 2019-08-06 The Spectranetics Corporation Tissue slitting methods and systems
US11596435B2 (en) 2012-09-14 2023-03-07 Specrtranetics Llc Tissue slitting methods and systems
US10531891B2 (en) 2012-09-14 2020-01-14 The Spectranetics Corporation Tissue slitting methods and systems
US9949753B2 (en) 2012-09-14 2018-04-24 The Spectranetics Corporation Tissue slitting methods and systems
US9724122B2 (en) 2012-09-14 2017-08-08 The Spectranetics Corporation Expandable lead jacket
US10383691B2 (en) 2013-03-13 2019-08-20 The Spectranetics Corporation Last catheter with helical internal lumen
US9291663B2 (en) 2013-03-13 2016-03-22 The Spectranetics Corporation Alarm for lead insulation abnormality
US10799293B2 (en) 2013-03-13 2020-10-13 The Spectranetics Corporation Laser ablation catheter
US9883885B2 (en) 2013-03-13 2018-02-06 The Spectranetics Corporation System and method of ablative cutting and pulsed vacuum aspiration
US9283040B2 (en) 2013-03-13 2016-03-15 The Spectranetics Corporation Device and method of ablative cutting with helical tip
US9937005B2 (en) 2013-03-13 2018-04-10 The Spectranetics Corporation Device and method of ablative cutting with helical tip
US10485613B2 (en) 2013-03-13 2019-11-26 The Spectranetics Corporation Device and method of ablative cutting with helical tip
US10265520B2 (en) 2013-03-13 2019-04-23 The Spetranetics Corporation Alarm for lead insulation abnormality
US9925371B2 (en) 2013-03-13 2018-03-27 The Spectranetics Corporation Alarm for lead insulation abnormality
US9456872B2 (en) 2013-03-13 2016-10-04 The Spectranetics Corporation Laser ablation catheter
US10835279B2 (en) 2013-03-14 2020-11-17 Spectranetics Llc Distal end supported tissue slitting apparatus
US9918737B2 (en) 2013-03-15 2018-03-20 The Spectranetics Corporation Medical device for removing an implanted object
US9956399B2 (en) 2013-03-15 2018-05-01 The Spectranetics Corporation Medical device for removing an implanted object
US9603618B2 (en) 2013-03-15 2017-03-28 The Spectranetics Corporation Medical device for removing an implanted object
US10448999B2 (en) 2013-03-15 2019-10-22 The Spectranetics Corporation Surgical instrument for removing an implanted object
US10314615B2 (en) 2013-03-15 2019-06-11 The Spectranetics Corporation Medical device for removing an implanted object
US10219819B2 (en) 2013-03-15 2019-03-05 The Spectranetics Corporation Retractable blade for lead removal device
US10524817B2 (en) 2013-03-15 2020-01-07 The Spectranetics Corporation Surgical instrument including an inwardly deflecting cutting tip for removing an implanted object
US10136913B2 (en) 2013-03-15 2018-11-27 The Spectranetics Corporation Multiple configuration surgical cutting device
US10052129B2 (en) 2013-03-15 2018-08-21 The Spectranetics Corporation Medical device for removing an implanted object
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US6575997B1 (en) 2003-06-10

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