US1934793A - Insufflator - Google Patents
Insufflator Download PDFInfo
- Publication number
- US1934793A US1934793A US596346A US59634632A US1934793A US 1934793 A US1934793 A US 1934793A US 596346 A US596346 A US 596346A US 59634632 A US59634632 A US 59634632A US 1934793 A US1934793 A US 1934793A
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- Prior art keywords
- powder
- tube
- magazine
- port
- valve
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- Expired - Lifetime
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
Definitions
- This invention relates to. and hasefo'r a purpose the provision ofa simple. andcolnpact device by which uid substancesfsuches highly hygro ⁇ scopic medicinal powder, .canl.be,.insuiilated into. y5. any orificev of the. human ibodif ⁇ with .the rutmost ease;- and; convenience.
- Aifurthenpurposeof-the invention' isj the provision ofianfinsuilatorfwithwhieh aY cartridge cond tainingsthe.;
- effetinalppowder isf adapted to be ldsassociatedr in a ma-nner..4 tofpractically 'sealg .the 'poiltlder;A against exposure' to moisturefinj the y air,
- Figure 1 is Aa. viewiy showing.. in plan one forni of.- insuiiiatoreembcuiyingvr this invention
- eachjofi thef-severall.views,. this invention inwits. presenti'embodimenti comprise a magazine medicant.v from; the .f magazille.Y .
- the tube-.12 is provided i with.: aY-ilangezlfifand .-with an enlarged andi: knurled portion. 15 from; which latten the tube is-iconsiderably recluced-jirn diameterl and.
- the .flange 14 and the knurled portion 15 are [forcef'a blast vof air throughthe tube 12 Vandfthenf Y Which'projects a lip 17 formed on a Alug 18 xed tothetube 11, forco-actionof the grooveand lip inconiihing. the .tube l2 ⁇ jagainst axialdisek .placement ⁇ from the tubetll while" permitting rotation ofthe tube.12.toopenandclose thevahre.
- the lug 181 extends aorossjafrecessed portion of. I I l the riian'ge 14;.p ⁇ rov ⁇ idil ⁇ 1g1 stop 'shoulders 19 ⁇ an d 20, ( Figure 5) fone of' which coiacts with'. theililg: to, limit rotation. of thetube 12in ⁇ one direction. to the; position wherein thepo'rts 10and'131register asv shown in the.drawing.A The. other stopv shoulder limits. the rotation ⁇ of the, tube ⁇ the reversedirectionto .a position Whereinthe ports v are" out of registration; as will be. understoodi The tube llis providedwith a sigljitbpening 21 through.
- V which suitable indicia kon the tubel12f can be viewed to'indicate:whether'thevalve o'ccu 'Fo'r.. use particulv rlywitlnthe insuillator', la.' car# tridge C containing the medicinal powder. to be used'is preferablyemployed-
- AXially disposed on the inner side of the disk 24 is a projection 30 which is adapted to enter the ports and i3 when all of the medicant has been forced from the cylinder 22 and the disk abuts the closed end of the magazine.
- the projection 30 V will operate to lock the valve V againstrotation, as an indication to the operator that the cartridge has been emptied of its contents.
- the tube 12 is now reversely rotatedto move the port 13 outofregistration with the port V10.
- the small'quantity ordose. of powder in the tube l2 ⁇ can be now blown therefrom by'r compressing the bulb B.V
- Any suitable form of applicator (notshown) can be applied to the free end of the tube 10 for insertion into Athe orifice of the body to be treated.
- the medicant powder is fof acharacter to render it non-packing sothat eachftime'the valve is opened, thesp'ring 26 and the disk 24 will coact to forceta small quantity or dose of the powder from the cartridge into the bore of the valve tube 12 for ejectionas desired.
- the cartridge and the manner in which it is associated with the device render it possible toutilize a soft and amorphous powder (non-crystalline), rather than the ordinary crystalline powder required for ⁇ the present types of ins'uiilators which have to be packed full by repeatedly pressing upon'the powderin the manner of filling a capsule.
- a soft and amorphous powdenproper insuiation is secured, with a complete diffusion of the particles on ythe membrane where they almost instantly dissolve and provide medication for hours, as compared 50 with minutes when the same ingredients are applied iny solution.
- An insuiflator comprising: a magazine in rwhich a supply of powder ⁇ isadapted to be stored,
- the magazine having an outlet port for the powder; means for urging the powder to discharge froml the magazinethrough said port; a valve tube mounted for movement and having aV port disposed to be registered'with'the rst'port when the tube occupies one position", for the discharge of powder from the magazine into the valve tube; and means for 'ejecting the powder from the valve tube.
- An insuiilator comprising: a magazine in which a supply of powder is adapted to be stored, the magazine having an outlet port for the powder; a spring pressed piston in the magazine for urging the powder to'discharge therefrom through said port; avalve for controlling the discharge of powder from said port; and means for subjecting to a blast of air powder discharged from the magazine.
- An insufator comprising: a magazine having an outlet port; a powder containing cartridge in the magazine having an open end exposed to the port, and a piston closing its other end; means co-acting with the piston to force the powder from the cartridge through said port; and means for subjecting to a blast of air, powder discharged from the cartridge.
- An in suiator comprising: a magazine in which a supply'of powder is adapted to be stored; the magazine having an outlet port for the powder; a spring pressed piston for forcing the powder to discharge' from the magazine; a movably .mounted valve tube having a port disposed to register with'vthe first port when theftube occupies vone position, f or the discharge of powder from the magazine intovthe valve tube; means for ejecting Apowder from the valve tube; and
- An insuiator comprising: a magazine in which a supply of powder is adapted to be stored;
- a -valve for controlling ⁇ the discharge ofA powder from themagazine; meansfor subjecting pow- .der discharged from themagazine, to a blast of cating intermediate its ends with said port; a
- Valve tube rotatably mounted in the i'lrst tube and having a port disposed to be brought into and .out of registration with the rst port during rotation of 'the valve tube means for forcing powder from the magazine into the valve tube when said ports are in registration; and means for subjecting powder in the valve tube to a blast of air so as to Vejectthe powder therefrom.
- An insuiator comprising: a magazine adapted to receive a supply-of powder'and having an outlet port for the discharge of ⁇ powder from the magazine; a tube on the magazine communicating intermediate its ends with saidport; a valve tube rotatably mounted in the first tube and having "a port disposed to be brought into and out of registration with the rst port during rotation of the valve tube; means for forcing powder fromv the magazine into the Valve tube when said ports are in registration; and means for locking the valve tube against rotation when the contents of the magazine has been forced therefrom.
- An insuiator comprising: a magazine adapted to receive a supply of powder and having an outlet port for ythe discharge of powder from the magazine; a tube on the magazine communieating intermediate its ends with said port; a valve" tube rotatably mounted inthe first tube lis isc
- Y e i, 1;.9341793l and having a port disposed to be'brought into and out of registration with the rstport during rotation of the Valve tube; a spring pressed pistonlin the magazine for forcing powder from the latter when said ports are in registration; andv a compressible bulb on theuvalve tube for fore-' ing air through the latter to ejectpowderin the;
- insufator l comprising: l adapted to receive a supply vof powder and hav'- ing an outlet port for the discharge of ⁇ powder ⁇ fromthe magazine; a tube on the magazine comv municating intermediate its ends with said port; a valve tube rotatably mounted in the rst tube and having a port disposed to be brought into andout of registration with the first port during o rotation of the valve tube; a spring pressed pisa magazine let tube and'fan outlet port communicating with mountedin the outlet'tube to control said port and enable a Vdose of powder to discharge from the magazine and 'beseparated from a supply therein;V and rmeans ⁇ for ejecting .the dose from' theoutlet tube; g l
- An insuiator comprising a magazine for a the interior of 1thetube a valve tube movably,V
- the magazine having an outlet tube'andan outletport. communicating with the interior lof the tube; a valve tube movably mountf ed in theoutlet tube to control said port and enable a dose of powder to discharge from the mag ⁇ azine and be separated from a Supply therein; and means for ejecting the dose fromthe outlet tube by a 'blast of air through the valve tube.
- An insufilator comprising: a magazinein which a supply of powder is adapted .to be stored,
Description
NOV. 14, 1933. D. CRA|N ET AL 1,934,793
INSUFFLATOR Y Filed March 2, 1932 INI/ENTORS ESTE/z D. CBA/N BY M/LTo/VJ. HuB/f/eD /1 TT ORNE YS.
Patented Nov. 14, 1933 rear-793 A yI1-zsUF11LAronv e rester' D. 10min, .Los Angelasi Jamil Milton J.
Hubbard, Inglewood, Calif.; said.
i signor .to said Crain Hubbard. als- Application Marel; 12, 1932. serial No. 596,346
. molaims.1011239266)V This invention relates to. and hasefo'r a purpose the provision ofa simple. andcolnpact device by which uid substancesfsuches highly hygro` scopic medicinal powder, .canl.be,.insuiilated into. y5. any orificev of the. human ibodif` with .the rutmost ease;- and; convenience.
Itis afiurther 'purposeof thel'invention to pro-ff' videfan: insufflator. structurally -oharact'erited byr means.V7 enablir'lgA relativelyr small. quantities.l or
laidoses from a supplyqof .thepow'der storedin the "device to .be insufllatedatthe will ofthe operator, Aifurthenpurposeof-the invention' isj the provision ofianfinsuilatorfwithwhieh aY cartridge cond tainingsthe.; medieinalppowder isf adapted to be ldsassociatedr in a ma-nner..4 tofpractically 'sealg .the 'poiltlder;A against exposure' to moisturefinj the y air,
v l whilefenablinglthe powder, toibe; discharged rrfor insuiiationunder the control Eofjtlie operator. r
One; formof... the. invention Will-'-v be described and :-its:novel-featuresfthen '.-poi-ntedV out v in claims. I
' Inithefaccompanyingdrawing,..
Figure 1 is Aa. viewiy showing.. in plan one forni of.- insuiiiatoreembcuiyingvr this invention;
25. elevation;
nieuwe.is@viewSimi1ar.torligure.2,`tut show-f- Figurez ism-:longitudinal.central sectional View.'V
of1thefn-1edicant icontaining-:cartridgewhich. is pare 3154.- ticularly adaptediforfusewiththe,insufator, Y'
` Referring speeicallyftofthe.drawing; iniwhich similari vreference characters designate similar.
p artsin eachjofi thef-severall.views,. this invention inwits. presenti'embodimenti comprise a magazine medicant.v from; the .f magazille.Y .The tube-.12 is provided i with.: aY-ilangezlfifand .-with an enlarged andi: knurled portion. 15 from; which latten the tube is-iconsiderably recluced-jirn diameterl and.
vspaceda'part to defineA an annl'llar groove 16 intov pies. ,opens or closed position;
v`frietior'lallyY tsinto va compressible bulb' B of rubber;` operating when compressed manually to` out of thereinoteend ofthe tube 11.
The .flange 14 and the knurled portion 15 are [forcef'a blast vof air throughthe tube 12 Vandfthenf Y Which'projects a lip 17 formed on a Alug 18 xed tothetube 11, forco-actionof the grooveand lip inconiihing. the .tube l2`jagainst axialdisek .placement `from the tubetll while" permitting rotation ofthe tube.12.toopenandclose thevahre.
The lug 181 extends aorossjafrecessed portion of. I I l the riian'ge 14;.p`rov`idil`1g1 stop 'shoulders 19 `an d 20, (Figure 5) fone of' which coiacts with'. theililg: to, limit rotation. of thetube 12in` one direction. to the; position wherein thepo'rts 10and'131register asv shown in the.drawing.A The. other stopv shoulder limits. the rotation `of the, tube` the reversedirectionto .a position Whereinthe ports v are" out of registration; as will be. understoodi The tube llis providedwith a sigljitbpening 21 through. Vwhich suitable indicia kon the tubel12f can be viewed to'indicate:whether'thevalve o'ccu 'Fo'r.. use particulv rlywitlnthe insuillator', la.' car# tridge C containing the medicinal powder. to be used'is preferablyemployed- This cartridge oom- .prisesan open ended cylinder522 of; transparent material suchas celluloidgnormally closed at'one end by .a-`anged capv23., ahdat'its opposite end by'a cupped disk 24"`vvhichY frictionallyjts into vthe cylinder and functions asa piston'in theuse gofjtheartridge.withthe device. .'Ihejcartridgejas .above described is packaged for saleV in a de. struetible. WrapperA 25. 'which hermetically' seals the contents: ofetlhexcartridge. v
With the. Wrapper 25 and thefc'ap'23fremoved f from the cylinder 22, the1aiier,cwhih isof.an
magazinais. inserted open` end foremost into' the magazine, after which a coil'spring 26 and then a closurecap 27. are: applied as shown in Figures.
external diameter to be snuglyreceived*inithev 'Y 3 and 4.' .A conventional'bayonetj slot and pin i connection 28 (FigureZ) detachably securesthe closure cap to the ymagazine Withthe ends of closure cap and the disk` 24 so as to.constantly urge the .latterimvardly of .thecylinden and thus operate .to force powdered medicine from the car- Ytridge into the tube 12, when its'port 13 is brought into registration with the port 10.
The sidewall of themagazme. ls` provided'at dia rnetrically,` opposed points' With longitudinal tridgeeanbe observed in orderforthe operatorl 1,00 the spring'261abutting the inner Wall of `the Yto ascertain lthe amount of medicant in the carltridge.
AXially disposed on the inner side of the disk 24 is a projection 30 which is adapted to enter the ports and i3 when all of the medicant has been forced from the cylinder 22 and the disk abuts the closed end of the magazine. In
. this position of the disk, the projection 30 Vwill operate to lock the valve V againstrotation, as an indication to the operator that the cartridge has been emptied of its contents.
In the operation of the insufflator, a lled cartridge C, from which the wrapper 25 and cap siton by grasping the magazine in one hand and rotating the bulb yB with the other, thespring 26 will forcev a small quantity o f the medicant powder from the cartridge through the registering'ports 10 and 13 into the bore of the tube l2.
:The tube 12 is now reversely rotatedto move the port 13 outofregistration with the port V10. The small'quantity ordose. of powder in the tube l2` can be now blown therefrom by'r compressing the bulb B.V Any suitable form of applicator (notshown) can be applied to the free end of the tube 10 for insertion into Athe orifice of the body to be treated. 'Itwillkbe understood that the medicant powder is fof acharacter to render it non-packing sothat eachftime'the valve is opened, thesp'ring 26 and the disk 24 will coact to forceta small quantity or dose of the powder from the cartridge into the bore of the valve tube 12 for ejectionas desired. y
The use of the cartridge and the manner in which it is associated with the device render it possible toutilize a soft and amorphous powder (non-crystalline), rather than the ordinary crystalline powder required for` the present types of ins'uiilators which have to be packed full by repeatedly pressing upon'the powderin the manner of filling a capsule. By the use of the soft and amorphous powdenproper insuiation is secured, with a complete diffusion of the particles on ythe membrane where they almost instantly dissolve and provide medication for hours, as compared 50 with minutes when the same ingredients are applied iny solution.
What.isclaimedis:` Y Y V1. An insulatoreccmprising: means for storing afsupply of powder; means for .urging the y powder to discharge from the rst means; valved from the magazine Ythrough said"port; a valveV for controlling the discharge vof powder from said port and by which a dose of the powder can be separated from the supply the magazine; and means for insuiilating the dose of powder.
3. An insuiflator comprising: a magazine in rwhich a supply of powder` isadapted to be stored,
the magazine having an outlet port for the powder; means for urging the powder to discharge froml the magazinethrough said port; a valve tube mounted for movement and having aV port disposed to be registered'with'the rst'port when the tube occupies one position", for the discharge of powder from the magazine into the valve tube; and means for 'ejecting the powder from the valve tube.
4. An insuiilator comprising: a magazine in which a supply of powder is adapted to be stored, the magazine having an outlet port for the powder; a spring pressed piston in the magazine for urging the powder to'discharge therefrom through said port; avalve for controlling the discharge of powder from said port; and means for subjecting to a blast of air powder discharged from the magazine.
5. An insufator comprising: a magazine having an outlet port; a powder containing cartridge in the magazine having an open end exposed to the port, and a piston closing its other end; means co-acting with the piston to force the powder from the cartridge through said port; and means for subjecting to a blast of air, powder discharged from the cartridge.
6. An in suiator comprising: a magazine in which a supply'of powder is adapted to be stored; the magazine having an outlet port for the powder; a spring pressed piston for forcing the powder to discharge' from the magazine; a movably .mounted valve tube having a port disposed to register with'vthe first port when theftube occupies vone position, f or the discharge of powder from the magazine intovthe valve tube; means for ejecting Apowder from the valve tube; and
means on the Apiston adapted to enter said ports and lock the valvetube against movement when the piston is forced toone extreme position.
'7. An insuiator comprising: a magazine in which a supply of powder is adapted to be stored;
means'for forcing powder from the magazine; a -valve for controlling `the discharge ofA powder from themagazine; meansfor subjecting pow- .der discharged from themagazine, to a blast of cating intermediate its ends with said port; a
Valve tube rotatably mounted in the i'lrst tube and having a port disposed to be brought into and .out of registration with the rst port during rotation of 'the valve tube means for forcing powder from the magazine into the valve tube when said ports are in registration; and means for subjecting powder in the valve tube to a blast of air so as to Vejectthe powder therefrom. i 9. An insuiator comprising: a magazine adapted to receive a supply-of powder'and having an outlet port for the discharge of `powder from the magazine; a tube on the magazine communicating intermediate its ends with saidport; a valve tube rotatably mounted in the first tube and having "a port disposed to be brought into and out of registration with the rst port during rotation of the valve tube; means for forcing powder fromv the magazine into the Valve tube when said ports are in registration; and means for locking the valve tube against rotation when the contents of the magazine has been forced therefrom.. f i
10. An insuiator comprising: a magazine adapted to receive a supply of powder and having an outlet port for ythe discharge of powder from the magazine; a tube on the magazine communieating intermediate its ends with said port; a valve" tube rotatably mounted inthe first tube lis isc
iis
ist
. Y e i, 1;.9341793l" and having a port disposed to be'brought into and out of registration with the rstport during rotation of the Valve tube; a spring pressed pistonlin the magazine for forcing powder from the latter when said ports are in registration; andv a compressible bulb on theuvalve tube for fore-' ing air through the latter to ejectpowderin the;
valve tube therefrom. f l
' 11.An insufator l; comprising: l adapted to receive a supply vof powder and hav'- ing an outlet port for the discharge of `powder` fromthe magazine; a tube on the magazine comv municating intermediate its ends with said port; a valve tube rotatably mounted in the rst tube and having a port disposed to be brought into andout of registration with the first port during o rotation of the valve tube; a spring pressed pisa magazine let tube and'fan outlet port communicating with mountedin the outlet'tube to control said port and enable a Vdose of powder to discharge from the magazine and 'beseparated from a supply therein;V and rmeans `for ejecting .the dose from' theoutlet tube; g l
13; An insuiator comprising a magazine for a the interior of 1thetube a valve tube movably,V
supplyof'powder; the magazine having an outlet tube'andan outletport. communicating with the interior lof the tube; a valve tube movably mountf ed in theoutlet tube to control said port and enable a dose of powder to discharge from the mag` azine and be separated from a Supply therein; and means for ejecting the dose fromthe outlet tube by a 'blast of air through the valve tube. y
14. An insufilator comprising: a magazinein which a supply of powder is adapted .to be stored,
the'magazine having an outlet port for the powder; a. Valve tubermounted for movement and.'
having aport disposed to be registered with the rstport when the tube occupies one position, Vfor the discharge of powder from the magazine into the valve tube; and means for ejecting the powder from the valve tube. g
Y LESTER D. CRAIN.
` MILTON J l. HUBBARD.
ist
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US596346A US1934793A (en) | 1932-03-02 | 1932-03-02 | Insufflator |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US596346A US1934793A (en) | 1932-03-02 | 1932-03-02 | Insufflator |
Publications (1)
Publication Number | Publication Date |
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US1934793A true US1934793A (en) | 1933-11-14 |
Family
ID=24386959
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US596346A Expired - Lifetime US1934793A (en) | 1932-03-02 | 1932-03-02 | Insufflator |
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Cited By (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2570774A (en) * | 1947-10-21 | 1951-10-09 | Frank P C Davis | Insufflator |
US3888252A (en) * | 1974-01-23 | 1975-06-10 | Anthony J Side | Powder inhaler |
US5273531A (en) * | 1992-09-21 | 1993-12-28 | Knoepfler Dennis J | Method of applying thrombic powder in laparoscopic procedures |
US5678538A (en) * | 1993-03-31 | 1997-10-21 | Fisons Plc | Inhalation device |
US20090211577A1 (en) * | 2005-04-08 | 2009-08-27 | Nycomed Gmbh | Device for Dosing and Dry Nebulization |
US20110066132A1 (en) * | 2009-09-17 | 2011-03-17 | Xin Ji | Internal dry powder delivery system and method thereof |
US20110178495A1 (en) * | 2010-01-15 | 2011-07-21 | Xin Ji | Internal dry powder delivery system and method thereof |
US8118777B2 (en) | 2009-05-29 | 2012-02-21 | Cook Medical Technologies Llc | Systems and methods for delivering therapeutic agents |
US8361054B2 (en) | 2008-12-23 | 2013-01-29 | Cook Medical Technologies Llc | Apparatus and methods for containing and delivering therapeutic agents |
US8575132B2 (en) | 2007-08-09 | 2013-11-05 | Xin Ji | Modified starch material of biocompatible hemostasis |
US9101744B2 (en) | 2009-05-29 | 2015-08-11 | Cook Medical Technologies Llc | Systems and methods for delivering therapeutic agents |
US9839772B2 (en) | 2008-05-06 | 2017-12-12 | Cook Medical Technologies Llc | Apparatus and methods for delivering therapeutic agents |
US9867931B2 (en) | 2013-10-02 | 2018-01-16 | Cook Medical Technologies Llc | Therapeutic agents for delivery using a catheter and pressure source |
US20190159617A1 (en) * | 2017-11-30 | 2019-05-30 | Harro Hoefliger Verpackungsmaschinen Gmbh | Device for the metered filling of a drinking straw with a filling material |
US10314937B2 (en) | 2014-09-18 | 2019-06-11 | Endoclot Plus Co., Ltd. | Biocompatible hemostatic product and preparation method thereof |
US20190255558A1 (en) * | 2018-02-20 | 2019-08-22 | Nick Dimakos | Applicators for applying fibers to surfaces |
US11213615B2 (en) | 2017-02-28 | 2022-01-04 | EndoClot Plus Co.. Ltd | Composition for submucosal injection, reagent combination, and applications thereof |
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1932
- 1932-03-02 US US596346A patent/US1934793A/en not_active Expired - Lifetime
Cited By (35)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2570774A (en) * | 1947-10-21 | 1951-10-09 | Frank P C Davis | Insufflator |
US3888252A (en) * | 1974-01-23 | 1975-06-10 | Anthony J Side | Powder inhaler |
US5273531A (en) * | 1992-09-21 | 1993-12-28 | Knoepfler Dennis J | Method of applying thrombic powder in laparoscopic procedures |
US5678538A (en) * | 1993-03-31 | 1997-10-21 | Fisons Plc | Inhalation device |
US20090211577A1 (en) * | 2005-04-08 | 2009-08-27 | Nycomed Gmbh | Device for Dosing and Dry Nebulization |
US9713682B2 (en) * | 2005-04-08 | 2017-07-25 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Device for dosing and dry nebulization |
US10195312B2 (en) | 2007-08-09 | 2019-02-05 | Xin Ji | Modified starch material of biocompatible hemostasis |
US10076590B2 (en) | 2007-08-09 | 2018-09-18 | Xin Ji | Modified starch material of biocompatible hemostasis |
US8912168B2 (en) | 2007-08-09 | 2014-12-16 | Xin Ji | Modified starch material of biocompatible hemostasis |
US8575132B2 (en) | 2007-08-09 | 2013-11-05 | Xin Ji | Modified starch material of biocompatible hemostasis |
US9533005B2 (en) | 2007-08-09 | 2017-01-03 | Xin Ji | Modified starch material of biocompatible hemostasis |
US9839772B2 (en) | 2008-05-06 | 2017-12-12 | Cook Medical Technologies Llc | Apparatus and methods for delivering therapeutic agents |
US10994110B2 (en) | 2008-05-06 | 2021-05-04 | Cook Medical Technologies Llc | Apparatus and methods for delivering therapeutic agents |
US8361054B2 (en) | 2008-12-23 | 2013-01-29 | Cook Medical Technologies Llc | Apparatus and methods for containing and delivering therapeutic agents |
US8118777B2 (en) | 2009-05-29 | 2012-02-21 | Cook Medical Technologies Llc | Systems and methods for delivering therapeutic agents |
US8728032B2 (en) | 2009-05-29 | 2014-05-20 | Cook Medical Technologies Llc | Systems and methods for delivering therapeutic agents |
US9375533B2 (en) | 2009-05-29 | 2016-06-28 | Cook Medical Technologies Llc | Systems and methods for delivering therapeutic agents |
US9101744B2 (en) | 2009-05-29 | 2015-08-11 | Cook Medical Technologies Llc | Systems and methods for delivering therapeutic agents |
US20110066132A1 (en) * | 2009-09-17 | 2011-03-17 | Xin Ji | Internal dry powder delivery system and method thereof |
US8721582B2 (en) * | 2009-09-17 | 2014-05-13 | Xin Ji | Internal dry powder delivery system and method thereof |
US20140207097A1 (en) * | 2010-01-15 | 2014-07-24 | Xin Ji | Internal Dry Powder Delivery System and Method Thereof |
US9629966B2 (en) * | 2010-01-15 | 2017-04-25 | Xin Ji | Internal dry powder delivery system and method thereof |
US20130046278A1 (en) * | 2010-01-15 | 2013-02-21 | Xin Ji | Internal Dry Powder Delivery System and Method Thereof |
US8827980B2 (en) * | 2010-01-15 | 2014-09-09 | Xin Ji | Internal dry powder delivery system and method thereof |
US9205207B2 (en) * | 2010-01-15 | 2015-12-08 | Xin Ji | Internal dry powder delivery system and method thereof |
US20110178495A1 (en) * | 2010-01-15 | 2011-07-21 | Xin Ji | Internal dry powder delivery system and method thereof |
US11931227B2 (en) | 2013-03-15 | 2024-03-19 | Cook Medical Technologies Llc | Bimodal treatment methods and compositions for gastrointestinal lesions with active bleeding |
US9867931B2 (en) | 2013-10-02 | 2018-01-16 | Cook Medical Technologies Llc | Therapeutic agents for delivery using a catheter and pressure source |
US11696984B2 (en) | 2013-10-02 | 2023-07-11 | Cook Medical Technologies Llc | Therapeutic agents for delivery using a catheter and pressure source |
US10806853B2 (en) | 2013-10-02 | 2020-10-20 | Cook Medical Technologies Llc | Therapeutic agents for delivery using a catheter and pressure source |
US10314937B2 (en) | 2014-09-18 | 2019-06-11 | Endoclot Plus Co., Ltd. | Biocompatible hemostatic product and preparation method thereof |
US11213615B2 (en) | 2017-02-28 | 2022-01-04 | EndoClot Plus Co.. Ltd | Composition for submucosal injection, reagent combination, and applications thereof |
US20190159617A1 (en) * | 2017-11-30 | 2019-05-30 | Harro Hoefliger Verpackungsmaschinen Gmbh | Device for the metered filling of a drinking straw with a filling material |
US11511312B2 (en) * | 2018-02-20 | 2022-11-29 | Surethik | Applicators for applying fibers to surfaces |
US20190255558A1 (en) * | 2018-02-20 | 2019-08-22 | Nick Dimakos | Applicators for applying fibers to surfaces |
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