EP0188981A1 - Double chamber mixing syringe - Google Patents

Double chamber mixing syringe Download PDF

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Publication number
EP0188981A1
EP0188981A1 EP85420235A EP85420235A EP0188981A1 EP 0188981 A1 EP0188981 A1 EP 0188981A1 EP 85420235 A EP85420235 A EP 85420235A EP 85420235 A EP85420235 A EP 85420235A EP 0188981 A1 EP0188981 A1 EP 0188981A1
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EP
European Patent Office
Prior art keywords
chamber
agitator
membrane
syringe
liquids
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Application number
EP85420235A
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German (de)
French (fr)
Inventor
Claude Bosson
Bernard Dessapt
Yves Arnissolle
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Individual
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Individual
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Publication date
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Publication of EP0188981A1 publication Critical patent/EP0188981A1/en
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Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D81/00Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents
    • B65D81/32Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents for packaging two or more different materials which must be maintained separate prior to use in admixture
    • B65D81/3255Containers provided with a piston or a movable bottom, and permitting admixture within the container
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F31/00Mixers with shaking, oscillating, or vibrating mechanisms
    • B01F31/44Mixers with shaking, oscillating, or vibrating mechanisms with stirrers performing an oscillatory, vibratory or shaking movement
    • B01F31/441Mixers with shaking, oscillating, or vibrating mechanisms with stirrers performing an oscillatory, vibratory or shaking movement performing a rectilinear reciprocating movement
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00Other mixers; Mixing plants; Combinations of mixers
    • B01F33/50Movable or transportable mixing devices or plants
    • B01F33/501Movable mixing devices, i.e. readily shifted or displaced from one place to another, e.g. portable during use
    • B01F33/5011Movable mixing devices, i.e. readily shifted or displaced from one place to another, e.g. portable during use portable during use, e.g. hand-held
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/71Feed mechanisms
    • B01F35/713Feed mechanisms comprising breaking packages or parts thereof, e.g. piercing or opening sealing elements between compartments or cartridges
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/71Feed mechanisms
    • B01F35/713Feed mechanisms comprising breaking packages or parts thereof, e.g. piercing or opening sealing elements between compartments or cartridges
    • B01F35/7137Piercing, perforating or melting membranes or closures which seal the compartments
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/71Feed mechanisms
    • B01F35/716Feed mechanisms characterised by the relative arrangement of the containers for feeding or mixing the components
    • B01F35/7163Feed mechanisms characterised by the relative arrangement of the containers for feeding or mixing the components the containers being connected in a mouth-to-mouth, end-to-end disposition, i.e. the openings are juxtaposed before contacting the contents

Definitions

  • the invention concerns a new type of double-chamber mixing syringe.
  • Double chamber mixing syringes have been known for a long time.
  • patent FR-A-2 160 668 it has for example been proposed to arrange the two mixing chambers each closed by a membrane, facing each other, then to place in the interval formed between the two chambers a screwable assembly containing a needle injection, intended when the time comes by bringing the two chambers together, to perforate the two membranes and thus allow the passage of liquid from one chamber to the other.
  • This type of syringe has hardly developed since it remains complex to produce, therefore costly, not very suitable for viscous products and finally sometimes difficult to handle.
  • the invention overcomes these drawbacks. It is aimed at a double-chamber mixing syringe which is easy to construct, economical, and does not present prohibitive sealing problems, and finally is easy to fill and to handle.
  • An agitator (7) coaxial with the piston (4) also moves longitudinally in the first chamber (2).
  • This agitator advantageously in the same material as the piston, for example in molded polypropylene, comprises a head (8) and at the end (9) disposed in the chamber (2) a disc (10) comprising orifices (11) intended to ensure the mixing of the mixture.
  • the bottom of the chamber (2) opposite the disc (10) has stops (12,13) also molded intended to facilitate the flow of the liquid contained in the second chamber (3) during the casting operation .
  • the face of the head (10) of the agitator (7) has a point (18) disposed opposite the membrane (6), intended to perforate this membrane (6) for the moment. come in order to ensure the mixing of the liquids contained in the two chambers (2) and (3).
  • this agitator (7) comprises a safety rod (19) placed at the end of the piston (4 ) which, under the effect of a simple pressure, is exceeded and thus allows the tip (18) to perforate the sealing membrane (6).
  • the end (14) of the chamber (3) secured to the body (1) has a thread for receiving a cap (15).
  • the volume of this chamber (3) can be varied for the same assembly, namely: 3 ′, 3 "(see FIGS. 3 and 4)
  • the cap (15,15 ', 15 ") is molded in the same plastic material as the entire syringe.
  • the inner end of the head (10) and the agitator (7), (9) has a tip (18) formed by a cylindrical body (28) * to the end of which the actual perforation point (18) is placed, the length L3 of the assembly being slightly less than the length of the chamber (3) and the diameter L2 of this cylindrical portion (28) being slightly less than the internal diameter L1 of the chamber (3).
  • the body (1) has at its end ears (16) and is closed by a screw cap (17).
  • This syringe is carried out as follows.
  • the chamber (2) is filled, the end of which is closed by the membrane (6) by means of the first liquid (1), such as for example silicone.
  • the piston (4) / agitator (7) assembly is made to enter this chamber, and the cap (17) is closed by screwing.
  • the second chamber (3) is filled in a known manner with the appropriate liquid such as the catalyst.
  • the appropriate liquid such as the catalyst.
  • the syringe is thus ready for use.
  • the user wishes to mix the two liquids, he slightly unscrews the plug (5), for example by a quarter of a turn so as to allow the passage of air later.
  • he pushes the agitator (7) so as to pass the rod (19), so that the point (18) comes to perforate the membrane (6).
  • the tip (18) enters the chamber (3), it drives the liquid contained in this chamber (3) towards the chamber (2).
  • the agitator (7) is given a longitudinal back-and-forth movement and the mixture is stirred by the displacement of the head (10) and the holes (11).
  • the plug (15) is completely unscrewed and by action on the piston (4), the mixture produced by the end (25) of the chamber (3) is expelled which thus forms a nozzle Release.
  • the second chamber (3) is screwed by its end (21) on a thread (20) formed for this purpose at the end of the body (1) at the membrane (6).
  • Unscrewing fins (22) allow this chamber (3) to be clamped when the end of the syringe comes.
  • This embodiment is of interest when it is necessary that all the liquid contained in the second chamber (3) is eliminated to avoid any subsequent problem, in particular of aggression.
  • the outer end of the chamber (3) comprises a pusher (23) intended to force after perforation of the membrane (6) the passage of the liquid contained in the second chamber (3) in the first chamber (2).
  • this type of syringe can be successfully used for mixing any product with two components requiring homogenization, especially in a sterile environment.

Abstract

Mixing syringe with a double chamber (2, 3) comprising: - two chambers (2, 3) disposed opposite each other and each containing a liquid intended to be mixed; - a membrane (6) for provisionally maintaining a leaktight seal between the two liquids (2, 3); - an agitator (7) capable of sliding in the first chamber (2) with a longitudinal to-and-fro movement and of stirring the two liquids (2, 3) once mixed; - a piston (4) coaxial to the agitator (7) to eject the mixed liquids out of the syringe via an exit nipple (5), characterised: - in that the two chambers (2, 3), disposed opposite each other, are separated by a leaktight membrane (6) which can be perforated; - and in that the end (18) of the agitator (7, 10) disposed in the first chamber (2) has the shape of a point (18) intended to perforate the said membrane (6) when it is desired to mix the two liquids. <IMAGE>

Description

L'inventiez concerne un nouveau type de seringue de mélange à double chambre.The invention concerns a new type of double-chamber mixing syringe.

Les seringues de mélange à double chambre sont connues depuis fort longtemps. Dans le brevet FR-A-2 160 668, on a par exemple proposé de disposer les deux chambres de mélange fermées chacune par une membrane, en regard, puis de placer dans l'intervalle formé entre les deux chambres un ensemble vissable contenant une aiguille d'injection, destinée le moment venu par rapprochement des deux chambres, à venir perforer les deux membranes et ainsi permettre le passage du liquide d'une chambre dans l'autre. Ce type de seringue ne s'est guère développé car elle reste complexe à réaliser, donc coûteuse, peu adaptée aux produits visqueux et enfin parfois difficile à manipuler.Double chamber mixing syringes have been known for a long time. In patent FR-A-2 160 668, it has for example been proposed to arrange the two mixing chambers each closed by a membrane, facing each other, then to place in the interval formed between the two chambers a screwable assembly containing a needle injection, intended when the time comes by bringing the two chambers together, to perforate the two membranes and thus allow the passage of liquid from one chamber to the other. This type of syringe has hardly developed since it remains complex to produce, therefore costly, not very suitable for viscous products and finally sometimes difficult to handle.

Dans la demande de brevet PCT-WO-84/00011 de l'un des déposants, on a proposé une seringe à double compartiment comportant un piston coulissant et un agitateur coaxial audit piston, apte à se déplacer dans la première chambre dans un mouvement longitudinal de va-et-vient de manière à assurer le brassage du mélange réalisé. Cette solution présente de nombreux avantages sur le plan pratique. Toutefois, la réalisation industrielle de cette disposition fait appel à un joint d'étanchéité a simple effet (joint à lèvres) qui, avec certains produits engendre des problèmes d'étanchéité, notamment dans le temps.In the patent application PCT-WO-84/00011 of one of the applicants, a double-chamber syringe has been proposed comprising a sliding piston and an agitator coaxial with said piston, able to move in the first chamber in a longitudinal movement back and forth so as to ensure mixing of the mixture produced. This solution has many practical advantages. However, the industrial implementation of this arrangement calls for a single-effect seal (lip seal) which, with certain products, causes sealing problems, especially over time.

L'invention pallie ces inconvénients. Elle vise une seringue de mélange à double chambre qui soit facile à construire, économique, et ne présente des problèmes rédhibitoires d'étanchéité, et enfin soit facile à remplir et à manipuler.The invention overcomes these drawbacks. It is aimed at a double-chamber mixing syringe which is easy to construct, economical, and does not present prohibitive sealing problems, and finally is easy to fill and to handle.

La seringue de mélange à double compartiment selon l'invention qui comprend :

  • - deux chambres disposées en regard contenant chacune un liquide destiné à être mélangé,
  • - une membrane pour maintenir provisoirement l'étanchéité entre les deux liquides,
  • - un agitateur, apte à coulisser dans la première chambre dans un mouvement de va-et-vient longitudinal et a assurer le brassage des deux liquides une fois mélangés,
  • - un piston coaxial audit agitateur, destiné à éjecter les liquides mélangés hors de la seringue à travers un embout de sortie,
The double-compartment mixing syringe according to the invention which comprises:
  • - two chambers arranged opposite, each containing a liquid intended to be mixed,
  • - a membrane to temporarily maintain the seal between the two liquids,
  • - an agitator, able to slide in the first chamber in a longitudinal back-and-forth movement and to ensure the mixing of the two liquids once mixed,
  • - a piston coaxial with said agitator, intended to eject the mixed liquids out of the syringe through an outlet nozzle,

se caractérise :characterized :

  • - en ce que les deux chambres disposées en regard l'une de l'autre sont séparées par une membrane d'étanchéité perforable ;- in that the two chambers arranged opposite one another are separated by a perforable sealing membrane;
  • - et en ce que l'extrémité de l'agitateur disposé dans la première chambre a la forme d'une pointe destinée à perforer ladite membrane lorsque l'on désire réaliser le mélange des deux liquides.- And in that the end of the agitator arranged in the first chamber has the shape of a point intended to perforate said membrane when it is desired to mix the two liquids.

Avantageusement, en pratique :

  • - les deux chambres de mélange en regard forment un corps unique séparé en deux compartiments élémentaires par ladite membrane également venue de moulage, l'extrémité de la deuxième chambre qui forme embout recevant un capuchon de fermeture ;
  • - ce capuchon de fermeture de la deuxième chambre est vissé sur l'embout de sortie ;
  • - ce capuchon vissé pénètre d'une longueur déterminée dans la deuxième chambre afin d'en réduire le volume ;
  • - cette deuxième chambre, alignée avec la première, est cylindrique, et la pointe de perforation fixée à l'extrémité de l'agitateur qui coulisse dans la première chambre est fixée à l'extrémité d'une portion cylindrique ont le diamètre est inférieur au diamètre interne de la deuxième chambre,de manière à assurer au mieux le passage du liquide de la deuxième chambre dans la . première chambre la longueur hors-tout de cette portion et de la pointe étant inférieure à la longueur de la deuxième chambre, ;
  • - l'agitateur comprend une tête en forme de disque fixée à l'extrémité de l'axe longitudinal coaxial à l'axe du piston, ce disque présente d'une part des orifices traversant régulièrement disposés et d'autre part, la pointe destinée à perforer la membrane de séparation;
  • - le fond de la première chambre disposé en regard de la tête de l'agitateur en forme de disque comporte des butées d'appui pour ce disque.
Advantageously, in practice:
  • - The two facing mixing chambers form a single body separated into two elementary compartments by said membrane also coming from molding, the end of the second chamber which forms a nozzle receiving a closure cap;
  • - This closing cap of the second chamber is screwed onto the outlet nozzle;
  • - This screwed cap penetrates a determined length into the second chamber in order to reduce the volume;
  • - This second chamber, aligned with the first, is cylindrical, and the perforation tip fixed at the end of the agitator which slides in the first chamber is fixed at the end of a cylindrical portion have the diameter is less than internal diameter of the second chamber, so as to best ensure the passage of the liquid from the second chamber into the. first chamber, the overall length of this portion and of the tip being less than the length of the second chamber;
  • - The agitator comprises a disc-shaped head fixed to the end of the longitudinal axis coaxial with the axis of the piston, this disc has on the one hand regularly through through orifices and on the other hand, the point intended perforating the separation membrane;
  • - The bottom of the first chamber arranged opposite the head of the disc-shaped agitator has abutments for supporting this disc.

La manière dont l'invention peut être réalisée et les avantages qui en découlent ressortiront mieux des exemples de réalisation qui suivent donnés à titre indicatif et non limitatif à l'appui des figures annexées.The manner in which the invention can be implemented and the advantages which ensue therefrom will emerge more clearly from the following exemplary embodiments given by way of indication and without limitation in support of the attached figures.

  • La figure 1 montre en coupe longitudinale une première forme de réalisation de l'invention.Figure 1 shows in longitudinal section a first embodiment of the invention.
  • La figure 2 est une coupe de l'ensemble piston/ agitateur de la figure 1 selon l'axe 1-1.Figure 2 is a section of the piston / agitator assembly of Figure 1 along axis 1-1.
  • Les figures 3 et 4 montrent deux formes de réalisation de l'embout de sortie et de la deuxième chambre.Figures 3 and 4 show two embodiments of the outlet nozzle and the second chamber.
  • La figure 5 est une vue agrandie de l'extrémité de l'agitateur en forme de pointe dans une forme de réalisation préférée.Figure 5 is an enlarged view of the tip end of the tip-shaped agitator in a preferred embodiment.
  • Les figures 6 et 7 montrent toujours en coupe longitudinale deux autres formes de réalisation de l'invention.Figures 6 and 7 always show in longitudinal section two other embodiments of the invention.

En se référant aux figures, la seringue à double compartiment se compose essentiellement d'un corps (1) monobloc moulé en matière plastique, notamment en polypropylène. Ce corps (1) formé de deux portions cylindriques définit deux chambres respectivement :

  • - une première chambre (2) destinée à recevoir un premier liquide tel que du silicone,
  • - une deuxième chambre (3) alignée et disposée en regard de la première chambre (2), destinée à recevoir un deuxième liquide, tel qu'un catalyseur, destiné à être mélangé au premier.
Referring to the figures, the double compartment syringe essentially consists of a one-piece body (1) molded from plastic, in particular polypropylene. This body (1) formed of two cylindrical portions defines two chambers respectively:
  • - a first chamber (2) intended to receive a first liquid such as silicone,
  • - A second chamber (3) aligned and arranged opposite the first chamber (2), intended to receive a second liquid, such as a catalyst, intended to be mixed with the first.

Ces deux chambres (2,3) cylindriques coaxiales sont séparées par une membrane d'étanchéité (6) également venue de moulage. Dans la première chambre (2), coulisse un piston (4) qui présente à son extrémité un joint (5) d'étanchéité classique, par exemple en caoutchouc naturel. Ce piston (4,5) a pour fonction, le moment venu, d'expulser le mélange par l'embout de sortie (25).These two coaxial cylindrical chambers (2,3) are separated by a sealing membrane (6) also coming from molding. In the first chamber (2), slides a piston (4) which has at its end a seal (5) conventional seal, for example natural rubber. This piston (4,5) has the function, when the time comes, of expelling the mixture through the outlet nozzle (25).

Un agitateur (7) coaxial au piston (4) se déplace également longitudinalement dans la première chambre (2). Cet agitateur avantageusement dans la même matière que le piston, par exemple en polypropylène moulé, comporte une tête (8) et à l'extrémité (9) disposée dans la chambre (2) un disque (10) comportant des orifices (11) destinés à assurer le brassage du mélange. Le fond de la chambre (2) en regard du disque (10) présente des butées (12,13) également venues de moulage destinées à faciliter l'écoulement du liquide contenu dans la deuxième chambre (3) lors de l'opération de coulage.An agitator (7) coaxial with the piston (4) also moves longitudinally in the first chamber (2). This agitator advantageously in the same material as the piston, for example in molded polypropylene, comprises a head (8) and at the end (9) disposed in the chamber (2) a disc (10) comprising orifices (11) intended to ensure the mixing of the mixture. The bottom of the chamber (2) opposite the disc (10) has stops (12,13) also molded intended to facilitate the flow of the liquid contained in the second chamber (3) during the casting operation .

Selon la caractéristique de l'invention, la face de la tête (10) de l'agitateur (7) comporte une pointe (18) disposée en regard de la membrane (6), destinée à venir perforer cette membrane (6) le moment venu afin d'assurer le mélange des liquides contenus dans les deux chambres (2) et (3).. Dans une autre variante, cet agitateur (7) comporte un jonc de sécurité (19) placé à l'extrémité du piston (4) qui, sous l'effet d'une simple pression, est dépassé et permet ainsi à la pointe (18) de venir perforer la membrane d'étanchéité (6).According to the characteristic of the invention, the face of the head (10) of the agitator (7) has a point (18) disposed opposite the membrane (6), intended to perforate this membrane (6) for the moment. come in order to ensure the mixing of the liquids contained in the two chambers (2) and (3). In another variant, this agitator (7) comprises a safety rod (19) placed at the end of the piston (4 ) which, under the effect of a simple pressure, is exceeded and thus allows the tip (18) to perforate the sealing membrane (6).

L'extrémité (14) de la chambre (3) solidaire du corps (1) comporte un pas de vis destiné à recevoir un capuchon (15). Selon la forme de la partie rentrante (26) de ce capuchon dans la chambre (3), on peut faire varier pour un même montage le volume de cette chambre (3) à savoir : 3', 3" (voir figures 3 et 4). Avantageusement, le capuchon (15,15',15") est moulé dans la même .-matière plastique que l'ensemble de la seringue.The end (14) of the chamber (3) secured to the body (1) has a thread for receiving a cap (15). Depending on the shape of the re-entrant part (26) of this cap in the chamber (3), the volume of this chamber (3) can be varied for the same assembly, namely: 3 ′, 3 "(see FIGS. 3 and 4) Advantageously, the cap (15,15 ', 15 ") is molded in the same plastic material as the entire syringe.

Dans la forme de réalisation préférée montrée à la figure 5, l'extrémité interne de la tête (10) et de l'agitateur (7), (9) présente une pointe (18) constituée par un corps cylindrique (28)*à l'extrémité duquel on dispose la pointe de perforation proprement dite (18), la longueur L3 de l'ensemble étant légèrement inférieure à la longueur de la chambre (3) et le diamètre L2 de cette portion cylindrique (28) étant légèrement inférieur au diamètre interne Ll de la chambre (3). De la sorte, lorsque la pointe (18) a perforé la membrane perforable (6), la pénétration de la portion cylindrique (28) dans la chambre (3) assure une meilleure éjection du liquide contenu dans cette chambre (3) vers la chambre (2) et ce, grâce notamment en coopération avec les butées (12,13).In the preferred embodiment shown in Figure 5, the inner end of the head (10) and the agitator (7), (9) has a tip (18) formed by a cylindrical body (28) * to the end of which the actual perforation point (18) is placed, the length L3 of the assembly being slightly less than the length of the chamber (3) and the diameter L2 of this cylindrical portion (28) being slightly less than the internal diameter L1 of the chamber (3). In this way, when the tip (18) has perforated the perforable membrane (6), the penetration of the cylindrical portion (28) in the chamber (3) ensures better ejection of the liquid contained in this chamber (3) towards the chamber (2) and this, in particular in cooperation with the stops (12,13).

Dans la forme de réalisation présentée, le corps (1) présente à son extrémité des oreilles (16) et est fermé par un bouchon vissable (17).In the embodiment presented, the body (1) has at its end ears (16) and is closed by a screw cap (17).

Le remplissage de cette seringue s'effectue de la manière suivante. On remplit la chambre (2) dont l'extrémité est fermée par la membrane (6) au moyen du premier liquide (1), tel que par exemple du silicone. On fait pénétrer dans cette chambre l'ensemble piston (4)/agitateur (7), et on ferme par vissage du capuchon (17).The filling of this syringe is carried out as follows. The chamber (2) is filled, the end of which is closed by the membrane (6) by means of the first liquid (1), such as for example silicone. The piston (4) / agitator (7) assembly is made to enter this chamber, and the cap (17) is closed by screwing.

On remplit de manière connue la deuxième chambre (3) par le liquide approprié tel que le catalyseur. On visse à l'extrémité (14) formant embout de sortie (25) le capucnon (15) selon le volume que l'on désire introduire dans cette chambre (3) (voir figures 3 et 4).The second chamber (3) is filled in a known manner with the appropriate liquid such as the catalyst. We screw at the end (14) forming an outlet nozzle (25) the cap (15) according to the volume that we want insert into this chamber (3) (see Figures 3 and 4).

La seringue se trouve ainsi prête à l'emploi. Lorsque l'utilisateur désire mélanger les deux liquides, il dévisse légèrement le bouchon (5), par exemple d'un quart de tour de manière à permettre ultérieurement le passage de l'air. Ensuite, il pousse l'agitateur (7) de manière à surpasser le jonc (19), de sorte que la pointe (18) vienne perforer la membrane (6). Lorsque la pointe (18) (voir notamment figure 5) pénètre dans la chambre (3), elle chasse le liquide contenu dans cette chambre (3) vers la chambre (2). A ce moment, on imprime à l'agitateur (7) un mouvement longitudinal de va-et-vient et le mélange se trouve brassé par le déplacement de la tête (10) et des trous (11). Lorsqu'on estime que le mélange est homogène, on dévisse complètement le bouchon (15) et par action sur le piston (4), on chasse le mélange réalisé par l'extrémité (25) de la chambre (3) qui forme ainsi embout de sortie.The syringe is thus ready for use. When the user wishes to mix the two liquids, he slightly unscrews the plug (5), for example by a quarter of a turn so as to allow the passage of air later. Then, he pushes the agitator (7) so as to pass the rod (19), so that the point (18) comes to perforate the membrane (6). When the tip (18) (see in particular Figure 5) enters the chamber (3), it drives the liquid contained in this chamber (3) towards the chamber (2). At this time, the agitator (7) is given a longitudinal back-and-forth movement and the mixture is stirred by the displacement of the head (10) and the holes (11). When it is considered that the mixture is homogeneous, the plug (15) is completely unscrewed and by action on the piston (4), the mixture produced by the end (25) of the chamber (3) is expelled which thus forms a nozzle Release.

Si le plus généralement, l'ensemble des pièces est en polypropylène, on peut utiliser d'autres matériaux dans la mesure où ceux-ci résistent aux liquides destinés à être mélangés et à répondre aux exigences de la pharmacopée.If more generally, all of the parts are made of polypropylene, other materials can be used as long as they resist liquids intended to be mixed and to meet the requirements of the pharmacopoeia.

Dans la forme de réalisation montrée à la figure 6, la deuxième chambre (3) vient se visser par son extrémité (21) sur un pas de vis (20) ménagé à cet effet à l'extrémité du corps (1) au niveau de la membrane (6). Des ailettes de dévisage (22) permettent de serrer cette chambre (3) le moment venu à l'extrémité de la seringue. Cette forme de réalisation présente de l'intérêt lorsqu'il est nécessaire que tout le liquide contenu dans la deuxième chambre (3) soit éliminé pour éviter tout problème ultérieur, notamment d'agression.In the embodiment shown in Figure 6, the second chamber (3) is screwed by its end (21) on a thread (20) formed for this purpose at the end of the body (1) at the membrane (6). Unscrewing fins (22) allow this chamber (3) to be clamped when the end of the syringe comes. This embodiment is of interest when it is necessary that all the liquid contained in the second chamber (3) is eliminated to avoid any subsequent problem, in particular of aggression.

Dans la forme de réalisation montrée à la figure 7, l'extrémité extérieure de la chambre (3) comporte un poussoir (23) destiné à forcer après perforation de la membrane (6) le passage du liquide contenu dans la deuxième chambre (3) dans la première chambre (2).In the embodiment shown in Figure 7, the outer end of the chamber (3) comprises a pusher (23) intended to force after perforation of the membrane (6) the passage of the liquid contained in the second chamber (3) in the first chamber (2).

Les seringues selon l'invention présentent de nombreux avantages par rapport aux solutions commercialisées à ce jour. On peut citer :

  • - un nombre réduit de pièces à savoir six dans la forme de réalisation la plus simple (corps, piston, deux capuchons, agitateur, jonc rapporté), ce qui réduit considérablement le coût ;
  • - la facilité de l'opération du remplissage qui peut être effectué de manière séparée ;
  • - la facilité de manipulation ;
  • - l'absence de problème d'étanchéité.
The syringes according to the invention have many advantages over the solutions marketed to date. We can cite :
  • - a reduced number of parts, namely six in the simplest embodiment (body, piston, two caps, agitator, attached rod), which considerably reduces the cost;
  • - the ease of the filling operation which can be carried out separately;
  • - ease of handling;
  • - the absence of sealing problem.

De la sorte, ce type de seringue peut être utilisé avec succès pour le mélange de tout produit à deux composants nécessitant une homogénéisation, notamment en milieu stérile. On peut citer l'utilisation en milieu médical, en milieu dentaire, en chirurgie, même en chimie tel que le mélange de résine ou de colle.In this way, this type of syringe can be successfully used for mixing any product with two components requiring homogenization, especially in a sterile environment. We can cite the use in medical environment, in dental environment, in surgery, even in chemistry such as the mixture of resin or glue.

Claims (8)

1/ Seringue de mélange à double chambre (2,3) comprenant : - deux chambres (2,3) disposées en regard l'une de l'autre, contenant chacune un liquide destinés à être mélangés ; - une membrane (6) pour maintenir provisoirement l'étanchéité entre les deux liquides (2,3) ; - un agitateur (7) apte à coulisser dans la première chambre (2) dans un mouvement de va-et-vient longitudinal et à assurer le brassage des deux liquides (2,3) une fois mélangés ; - un piston (4) coaxial à l'agitateur (7) pour éjecter les liquides mélangés hors de la seringue à travers un embout de sortie (5),
caractérisée : - en ce que les deux chambres (2,3), disposées en regard l'une de l'autre, sont séparées par une membrane d'étanchéité (6) perforable ; - et en ce que l'extrémité (18) de l'agitateur (7, 10) disposée dans la première chambre (2) a la forme d'une pointe (18) destinée à perforer ladite membrane (6) lorsque l'on désire réaliser le mélange des deux liquides.
1 / Double chamber mixing syringe (2,3) comprising: - Two chambers (2,3) arranged opposite one another, each containing a liquid intended to be mixed; - a membrane (6) to temporarily maintain the seal between the two liquids (2,3); - an agitator (7) able to slide in the first chamber (2) in a longitudinal reciprocating movement and to ensure the mixing of the two liquids (2,3) once mixed; - a piston (4) coaxial with the agitator (7) for ejecting the mixed liquids out of the syringe through an outlet nozzle (5),
characterized: - in that the two chambers (2,3), arranged opposite one another, are separated by a perforable sealing membrane (6); - And in that the end (18) of the agitator (7, 10) disposed in the first chamber (2) has the shape of a point (18) intended to perforate said membrane (6) when one wishes to mix the two liquids.
2/ Seringue selon la revendication 1, caractérisée en ce que les deux chambres en regard (2,3) forment un corps unique (1) séparé en deux compartiments élémentaires (2,3) par ladite membrane (6) également venue de moulage, l'extrémité de la deuxième chambre (3) qui forme embout de sortie (25) recevant un capuchon (15) de fermeture.2 / Syringe according to claim 1, characterized in that the two facing chambers (2,3) form a single body (1) separated into two elementary compartments (2,3) by said membrane (6) also coming from molding, the end of the second chamber (3) which forms an outlet nozzle (25) receiving a closure cap (15). 3/ Seringue selon la revendication 2, caractérisée en ce que le capuchon (15) de fermeture de la deuxième chambre (3) est vissé sur l'embout (14).3 / syringe according to claim 2, characterized in that the cap (15) for closing the second chamber (3) is screwed onto the nozzle (14). 4/ Seringue selon la revendication 3, caractérisée en ce que le capuchon vissé (15) pénètre d'une longueur. déterminée dans la deuxième chambre (3) pour en réduire le volume.4 / syringe according to claim 3, characterized in that the screw cap (15) penetrates a length. determined in the second chamber (3) to reduce the volume. 5/ Seringue selon l'une des revendications 1 à 4, caractérisée en ce que la deuxième chambre (3) alignée avec la première (2) est cylindrique et, la pointe (18) de perforation, fixée à l'extrémité (10) de l'agitateur (7) qui coulisse dans la première chambre (2) présente une portion cylindrique (28) dont le diamètre L2 est inférieur au diamètre interne Ll de la deuxième chambre (3), de manière à assurer au mieux le passage du liquide de la deuxième chambre (3) dans la première (2), la longueur hors-tout -L3 de cette portion (28) et de la pointe (18) étant inférieure à la longueur de la deuxième chambre (3).5 / syringe according to one of claims 1 to 4, characterized in that the second chamber (3) aligned with the first (2) is cylindrical and, the point (18) of perforation, fixed to the end (10) of the agitator (7) which slides in the first chamber (2) has a cylindrical portion (28) whose diameter L2 is less than the internal diameter L1 of the second chamber (3), so as to best ensure the passage of the liquid from the second chamber (3) in the first (2), the overall length -L3 of this portion (28) and of the tip (18) being less than the length of the second chamber (3). 6/ Seringue selon l'une des revendications 1 à 5, caractérisée en ce que l'agitateur (7) comprend une tête (10) en forme de disque fixée à l'extrémité (9) de l'axe longitudinal (7) coaxial à l'axe du piston (4), ce disque (10) présentant d'une part des orifices (11) tra - versant régulièrement disposés et d'autre part, la pointe (18) destinée à perforer la membrane (6) de séparation.6 / syringe according to one of claims 1 to 5, characterized in that the agitator (7) comprises a head (10) in the form of a disc fixed to the end (9) of the longitudinal axis (7) coaxial to the axis of the piston (4), this disc (10) having on the one hand regularly-arranged orifices (11) passing through and on the other hand, the point (18) intended to perforate the membrane (6) of separation. 7/ Seringue selon l'une des revendications 1 à 6, caractérisée en ce que le fond de la première chambre (2) disposé en regard de la tête (10) de l'agitateur (7) sous forme de disque comporte des butées (12,13) d'appui pour ce disque.7 / syringe according to one of claims 1 to 6, characterized in that the bottom of the first chamber (2) disposed opposite the head (10) of the agitator (7) in the form of a disc has stops ( 12,13) of support for this disc. 8/ Seringue de mélange à double chambre caractérisée en ce qu'elle comprend : - un corps cylindrique monobloc (1) définissant et délimitant deux chambres élémentaires (2,3) recevant chacune un liquide destiné à être mélangé avec l'autre liquide, lesdites chambres (2,3) étant alignées et séparées par une membrane (6) d'étanchéité perforable, et venue de moulage ; - un piston (4) apte à coulisser longitudinalement dans la première chambre (2), destiné à éjecter les deux liquides une fois mélangés hors de la seringue par l'embout (25) formé par l'extrémité de l'autre chambre (3) ; - un agitateur (7) apte également à coulisser longitudinalement dans cette même première chambre (2) et dans la même chambre que le piston (4), comprenant : . un axe longitudinal (7) coaxial à l'axe du piston (4), . une tête en forme de disque (10) perforée (11) fixée à l'extrémité (9) de cet axe (7), . une pointe (18) fixée sur le disque (10) du côté opposé à l'axe (7), dont la forme (28, 18) et les dimensions sont sensiblement inférieures à celles de la deuxième chambre (3), . un capuchon (15) vissé à l'extrémité (14) de la deuxième chambre (3) en forme d'embout (25) et qui pénètre sur une longueur déterminée dans cette deuxième chambre (3). 8 / Double chamber mixing syringe characterized in that it comprises: - a one-piece cylindrical body (1) defining and delimiting two elementary chambers (2,3) each receiving a liquid intended to be mixed with the other liquid, said chambers (2,3) being aligned and separated adorned by a perforable sealing membrane (6), and molded; - A piston (4) able to slide longitudinally in the first chamber (2), intended to eject the two liquids once mixed out of the syringe by the nozzle (25) formed by the end of the other chamber (3 ); - an agitator (7) also capable of sliding longitudinally in this same first chamber (2) and in the same chamber as the piston (4), comprising: . a longitudinal axis (7) coaxial with the axis of the piston (4), . a perforated disc-shaped head (10) (11) fixed to the end (9) of this axis (7), . a point (18) fixed to the disc (10) on the side opposite the axis (7), the shape (28, 18) and the dimensions of which are substantially smaller than those of the second chamber (3), . a cap (15) screwed to the end (14) of the second chamber (3) in the form of a nozzle (25) and which penetrates over a determined length in this second chamber (3).
EP85420235A 1984-12-21 1985-12-19 Double chamber mixing syringe Withdrawn EP0188981A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8420091 1984-12-21
FR8420091A FR2575083A1 (en) 1984-12-21 1984-12-21 DOUBLE CHAMBER IMPROVED MIXING SYRINGE

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Cited By (14)

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FR2602420A1 (en) * 1986-08-08 1988-02-12 G C Dental Ind Corp CAPSULES FOR DENTAL RECONSTRUCTION MATERIALS
EP0282871A2 (en) * 1987-03-18 1988-09-21 Alfred Fischbach Kunststoffspritzgusswerk Mixing device for pasty multy-component substancies
EP0299433A1 (en) * 1987-07-15 1989-01-18 Alfred Fischbach Kunststoffspritzgusswerk Device for mixing or homogeneiring the content of a cartridge
FR2630661A1 (en) * 1988-04-29 1989-11-03 Matra Device for bringing into contact and mixing a liquid and another product and modular apparatus comprising its application
FR2649334A1 (en) * 1989-07-06 1991-01-11 Conseil Rech Etu Engineering Device for mixing and ejecting two liquids
FR2658487A1 (en) * 1990-02-21 1991-08-23 Valois Device for spraying a medicine constituted by a mixture to be formed at the moment of emission
EP0652019A1 (en) * 1993-11-08 1995-05-10 Ferring Arzneimittel GmbH Mixing and administration syringe
GB2338428A (en) * 1998-06-19 1999-12-22 David Grant A syringe with an agitator whose shaft passes through a slidable dispensing plunger
WO2004026377A1 (en) * 2002-09-17 2004-04-01 Kyphon Inc. Apparatus and methods for mixing two components
WO2007095036A2 (en) * 2006-02-10 2007-08-23 Dow Global Technologies Inc. Retractable pin mixing sample forming device and method
US7998106B2 (en) 2004-05-03 2011-08-16 Thorne Jr Gale H Safety dispensing system for hazardous substances
CN105611854A (en) * 2013-09-13 2016-05-25 衍宇株式会社 Syringe-type cosmetic container
WO2016188096A1 (en) * 2015-05-27 2016-12-01 Abon Biopharm(Hangzhou) Co. Ltd. A mixing device
US10159948B2 (en) 2013-03-04 2018-12-25 3P Innovation Limited Drum agitation actuator having a series of offset magnets

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US3164303A (en) * 1961-12-04 1965-01-05 Semco Res Inc Storage and mixing cartridge
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US3548562A (en) * 1968-06-24 1970-12-22 Gilbert Schwartzman Method of producing a mixing package employing two separate containers
FR2131809A1 (en) * 1971-03-29 1972-11-17 Duraffourd Paul
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US3164303A (en) * 1961-12-04 1965-01-05 Semco Res Inc Storage and mixing cartridge
US3144966A (en) * 1962-04-16 1964-08-18 Semco Res Inc Cartridge for mixing and dispensing sealant compound
US3195778A (en) * 1963-09-17 1965-07-20 Alta Engineering Company Storage and mixing cartridge
US3437242A (en) * 1966-11-21 1969-04-08 Edward J Poitras Fluid storing,mixing and dispensing apparatus
US3370754A (en) * 1966-12-21 1968-02-27 Products Res & Chemical Corp Syringe for mixing and dispensing two ingredients
DE1805110A1 (en) * 1968-04-24 1969-11-06 Products Res & Chemical Corp Dispenser cartridge for mixing separate substances
US3548562A (en) * 1968-06-24 1970-12-22 Gilbert Schwartzman Method of producing a mixing package employing two separate containers
FR2131809A1 (en) * 1971-03-29 1972-11-17 Duraffourd Paul
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Cited By (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2602420A1 (en) * 1986-08-08 1988-02-12 G C Dental Ind Corp CAPSULES FOR DENTAL RECONSTRUCTION MATERIALS
BE1002959A3 (en) * 1986-08-08 1991-10-08 G C Dental Ind Corp CAPSULE FOR DENTAL RECONSTRUCTION MATERIAL.
EP0282871A2 (en) * 1987-03-18 1988-09-21 Alfred Fischbach Kunststoffspritzgusswerk Mixing device for pasty multy-component substancies
EP0282871A3 (en) * 1987-03-18 1990-05-16 Alfred Fischbach Kunststoffspritzgusswerk Mixing device for pasty multy-component substancies
EP0299433A1 (en) * 1987-07-15 1989-01-18 Alfred Fischbach Kunststoffspritzgusswerk Device for mixing or homogeneiring the content of a cartridge
WO1989000536A1 (en) * 1987-07-15 1989-01-26 Alfred Fischbach Kg Kunststoff-Spritzgusswerk Mixing device
FR2630661A1 (en) * 1988-04-29 1989-11-03 Matra Device for bringing into contact and mixing a liquid and another product and modular apparatus comprising its application
FR2649334A1 (en) * 1989-07-06 1991-01-11 Conseil Rech Etu Engineering Device for mixing and ejecting two liquids
FR2658487A1 (en) * 1990-02-21 1991-08-23 Valois Device for spraying a medicine constituted by a mixture to be formed at the moment of emission
US5630800A (en) * 1993-11-08 1997-05-20 Ferring Arzneimettel Gmbh Injection syringe for the missing and application of injection substances
EP0652019A1 (en) * 1993-11-08 1995-05-10 Ferring Arzneimittel GmbH Mixing and administration syringe
GB2338428A (en) * 1998-06-19 1999-12-22 David Grant A syringe with an agitator whose shaft passes through a slidable dispensing plunger
WO2004026377A1 (en) * 2002-09-17 2004-04-01 Kyphon Inc. Apparatus and methods for mixing two components
US7018089B2 (en) 2002-09-17 2006-03-28 Kyphon Inc. Apparatus and methods for mixing two components
US7998106B2 (en) 2004-05-03 2011-08-16 Thorne Jr Gale H Safety dispensing system for hazardous substances
WO2007095036A3 (en) * 2006-02-10 2007-10-04 Dow Global Technologies Inc Retractable pin mixing sample forming device and method
WO2007095036A2 (en) * 2006-02-10 2007-08-23 Dow Global Technologies Inc. Retractable pin mixing sample forming device and method
US8220985B2 (en) 2006-02-10 2012-07-17 Dow Global Technologies Llc Retractable pin mixing sample forming device
US10159948B2 (en) 2013-03-04 2018-12-25 3P Innovation Limited Drum agitation actuator having a series of offset magnets
CN105611854A (en) * 2013-09-13 2016-05-25 衍宇株式会社 Syringe-type cosmetic container
EP3045072A1 (en) * 2013-09-13 2016-07-20 Yonwoo Co., Ltd Syringe-type cosmetic container
EP3045072A4 (en) * 2013-09-13 2017-04-05 Yonwoo Co., Ltd Syringe-type cosmetic container
WO2016188096A1 (en) * 2015-05-27 2016-12-01 Abon Biopharm(Hangzhou) Co. Ltd. A mixing device

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