EP0080379A1 - Connector assembly for liquid flow systems - Google Patents
Connector assembly for liquid flow systems Download PDFInfo
- Publication number
- EP0080379A1 EP0080379A1 EP82306262A EP82306262A EP0080379A1 EP 0080379 A1 EP0080379 A1 EP 0080379A1 EP 82306262 A EP82306262 A EP 82306262A EP 82306262 A EP82306262 A EP 82306262A EP 0080379 A1 EP0080379 A1 EP 0080379A1
- Authority
- EP
- European Patent Office
- Prior art keywords
- valve
- sleeve
- plug body
- plug
- socket
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M39/00—Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
- A61M39/02—Access sites
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M39/00—Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
- A61M39/22—Valves or arrangement of valves
- A61M39/26—Valves closing automatically on disconnecting the line and opening on reconnection thereof
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- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
- F16L—PIPES; JOINTS OR FITTINGS FOR PIPES; SUPPORTS FOR PIPES, CABLES OR PROTECTIVE TUBING; MEANS FOR THERMAL INSULATION IN GENERAL
- F16L37/00—Couplings of the quick-acting type
- F16L37/28—Couplings of the quick-acting type with fluid cut-off means
- F16L37/30—Couplings of the quick-acting type with fluid cut-off means with fluid cut-off means in each of two pipe-end fittings
- F16L37/32—Couplings of the quick-acting type with fluid cut-off means with fluid cut-off means in each of two pipe-end fittings at least one of two lift valves being opened automatically when the coupling is applied
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M39/00—Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
- A61M39/22—Valves or arrangement of valves
- A61M39/26—Valves closing automatically on disconnecting the line and opening on reconnection thereof
- A61M2039/266—Valves closing automatically on disconnecting the line and opening on reconnection thereof where the valve comprises venting channels, e.g. to insure better connection, to help decreasing the fluid space upon disconnection, or to help the fluid space to remain the same during disconnection
Definitions
- This invention relates to a plug-and-socket type connector assembly incorporating a cut-off valve which is intended to be substantially drip-proof in operation, the connector assembly being primarily intended to be incorporated between a surgical drain of a patient and a liquid receptacle such as a plastics bag.
- the present invention provides a connector assembly for use in a liquid flow system, such as a surgical drainage system, including releasably coo D erable plug and socket Darts, one of the parts incorporating a first valve and the other of the parts incorporating a second valve, operable to permit liquid to flow between the parts when plugged together, and effectively to prevent liquid spillage from the parts when unplugged, both valves being actuated by the relative plugging and unplugging movement between the plug and socket parts, the valves being arranged and adapted, during unplugging movement between the parts, to close in a manner which avoids the formation of any voids therebetween capable of accommodating sufficient liquid to form drips.
- a liquid flow system such as a surgical drainage system
- the present invention provides a connector assembly for use in a liquid flow system, including releasably cooperable plug and socket parts incorporating a valve arrangement for cutting-off liquid flow through the plug and socket parts when unplugged, the plug part having a slide valve and comprising a tubular plug body closed at one end and having at least one opening near the closed end, and a sleeve surrounding the plug body, the plug body and sleeve being relatively slidable between a valve-closed position in which the sleeve closes the opening in the plug body, and a valve-open position in which the sleeve does not close the opening, the socket part comprising a tubular socket body having an open end for receiving the closed end of the plug body, and a flap valve spaced from the open end of the socket body, plugging movement between the plug and socket parts being operable both to cause displacement of the flap valve, and of the plug body and sleeve, to their valve-open positions in which a liquid path is established between the plug and socket
- the invention also consists in a liquid flow system incorporating one or more connector assemblies as above defined.
- the liquid flow system may comprise a surgical drainage system including a liquid receptacle, a catheter or other drain means cooperable with a patient, and a liquid line, interconnecting the drain means and receptacle, incorporating a connector assembly as above defined.
- the components of the valve are integrated parts of the connecting members, i.e. the plug and socket parts, between the drainage line or hose and the receptacle or bag.
- the connecting action itself causes a valve to open in both the plug part and the socket part and thereby allows the passage of liquid through the system. Likewise, both valves are caused to close immediately the system is disconnected, avoiding waste from the connection or joint.
- the plug part and socket part are, respectively, welded or glued to the ends of lengths of drainage hose leading to the bag and a catheter or other drain means.
- the tubular plug body which is closed by an externally planar transverse end wall at its far or distal end, is provided with side openings in its cylindrical surface or wall quite near to the end wall.
- the tubular sleeve is slidable lengthwise between two extreme positions, namely between valve-open and valve-closed positions. This assembly can slide into the tubular socket body of the socket part to a fully introduced position of the sleeve, the sleeve and plug body moving in unison to this position.
- the plug body is then advanced a small distance further, causing the sleeve to slide back relative to the plug body, to a position in which it clears the openings in the plug body and the openings communicate with the interior of the socket part.
- the distal end of the plug body will lift the flap-valve at the bottom or proximal end of the socket body and thus allow a liquid to flow through the system.
- the plug body When, due to the need to exchange the bag, the plug part has to be disengaged from the socket part, the plug body, as it is being withdrawn, will initially lower the flap-valve, allowing it to close, and at the same time cause the sleeve to slide forwards and cover the openings of the plug body. These movements will follow, surface to surface,and in no situation leave empty spaces or voids for liquid. It is of great importance, apart from the function of the valve arrangement described, to achieve an economic solution, as it must be remembered, that the article is to be considered as disposable.
- the surgical drainage system includes a synthetic plastics bag 1 connected to a drainage line or hose 2a, 2b incorporating a coupling or connector assembly comprising a male or plug part 3 and a female or socket part 4.
- the plug and socket parts are formed, for example moulded, from suitable resilient, self-supporting, synthetic plastics material or materials.
- the plug part 3 includes a tubular, cylindrical body 3a, one end of which is secured at 2e, for example by welding or gluing, within an end of the section 2a of the drainage hose directly connected to the bag 1.
- the outer or distal end of the plug body 3a is closed by a transverse end wall 3b and,adjacent the end wall, the cylindrical side wall of the plug body is perforated by circumferentially extending openings 3c.
- a valve element comprising a cylindrical sleeve 3d closely fits the outer cylindrical surface of the plug body.
- the plug body is slidable axially within the sleeve 3d from a retracted or valve-closed position as shown in Figure 1, in which the outer or distal end of the sleeve is substantially flush with the planar outer surface of the transverse end wall 3b, and the sleeve overlies and seals off the openings 3c, to a valve-open position as shown in Figure 2, in which the distal end of the plug body 3a is advanced relative to the sleeve 3d to expose and open the openings 3c.
- the proximal end of the sleeve is provided with internal and external annular flanges 3e and 3f respectively.
- the internal flange 3e engages in a reduced diameter portion of the plug body, and is cooperable with stops formed by opposed shoulders 3g and 3h of the body to predetermine the range of sliding movement of the sleeve relative to the plug body.
- the shoulder 3h is formed at one end of an annular collar 3i integral with the plug body and formed with integral diametrically opposed pins 3k forming part of a bayonet-type locking arrangement.
- the sleeve 3d is initially assembled to the plug body 3a by pressing the flanged proximal end of the sleeve over the distal end of the plug body, and to simplify this operation, the internal flange 3e is formed with a tapered radially inner surface to provide a lead-in. 2a
- the socket part 4 is also tubular, and has a reduced diameter end portion 4a secured, for example by welding or gluing, to an end of the section 2b of drainage hose intended to be connected to a catheter or other drain.
- the end portion 4a communicates with one end of an enlarged diameter cylindrical/portion 4b defining a tubular chamber, the other end of the chamber communicating with a tubular socket body 4c internally dimensioned to slidably receive the plug part 3.
- the cylindrical portion 4b is sufficiently resilient or flexible to permit it to be compressed manually, and the hose section 2b terminates, within the chamber, in a - non-return valve 2d which prevents liquid or gas, and any bacteria etc., within the chamber from passing back up the hose section.
- the non-return valve 2d (and the valve 2c) may be of the type which comprises a length of open-ended, flat or collapsed flexible tubing, formed, for example, from two elongate flat strips of plastics material welded together along their longer edges.
- the socket body 4c is provided, at its proximal end, with an internal annular flange 4d which serves as a stop for the sleeve 3d.
- the opening in the flange 4d is bounded by an annular ridge forming a seat 4e for a flap or disc valve element 5.
- the valve element 5 includes a circular, flat elastomeric sealing disc 5a bonded or otherwise secured to the flat end face of a closed-ended cylindrical support member 5b located within the cylindrical portion or chamber 4b.
- the disc valve element 5 is displaceable, and is biased by a coil spring 5c so as normally to urge the disc 5a towards the seat 4e to close, or tend or close, the opening in the flange 4d.
- the disc valve element 5 and bias spring 5c are located in a perforate housing 4f secured to the base of the cylindrical portion or chamber 4b,with the spring 5c maintained in compression between the disc valve element 5 and the underside of the top or end wall of the housing 4f.
- the inner diameter of the flange 4d i.e. the diameter of the opening in the flange, is approximately the same as the external diameter of the distal end region of the plug body 3a, so that the latter end region will be snugly slidably received by the flange when the plug and socket parts are connected together as shown in Figure 2.
- the cylindrical passage within the socket body 4c is provided with a reduced diameter region 4g adjacent the flange 4d, which is slightly smaller in diameter than the distal end of the sleeve 3d. Between the region 4 and an annular recess 4h, the internal diameter of the socket body 4c approximates or is slightly greater than the diameter of the sleeve 3d but less than the diameter of the external flange 3f.
- the distal region of the passage in the socket body 4c for example the region between the recess 4h and the open end of the body, may be internally stepped or tapered to provide an increased-diameter lead-in portion to facilitate insertion of the sleeve 3d. This distal region is also formed with a pair of slots 4i, forming part of the bayonet-type locking arrangement, and cooperable with the pins 3k.
- the connector assembly operates as follows:-
- the frictional cooperation between the plug body 3a and sleeve 3d is preferably initially greater than that between the sleeve 3d and internal surface of the socket body 4c. Therefore, the plug body and sleeve travel together, i.e. in their valve-closed position ( Figure 1),until the external flange 3f engages the distal end of the socket body 4c. Further insertion of the plug part then causes the plug body to advance relative to the sleeve until the proximal end of the sleeve engages the shoulder 3h.
- the sleeve 3d sealingly cooperates with the plug body 3a and socket body 4c, the distal end of the sleeve engages the flange 4d and sealingly cooperates with the reduced diameter region 4g, and the plug body is snugly received in the opening in the flange 4d, leakage between the plug and socket parts is prevented.
- the sleeve does not slide back on the plug body when, during insertion, the flange 3f engages the socket body, it will do so when its distal end encounters the region 4g. In any event, the sleeve will be positively driven fully home against the flange 4d, and the flange 3f will be snapped into the recess 4h, by engagement of the sleeve with the shoulder 3h.
- the flexible cylindrical socket portion 4b may be compressed, closing the non-return valve 2d, to pump or force the liquid through the openings and clear the blockage.
- the valve 2d isolates the patient from contaminants and pressure buildups downstream of the valve, and the valve 2c likewise prevents any contaminants, liquid, and pressure buildups in the bag from being transmitted to the connector assembly.
- the plug body 3a is firstly retracted relative to the socket body 4c and sleeve 3d until the upper surface of its transverse end wall 3b is flush with the upper edge of the valve seat 4e, so that the elastomeric disc 5a of the disc valve element 5 will seat and seal on the valve seat 4e without any significant voids, and therefore without any significant amounts of liquid being trapped, between the planar opposed surfaces of the disc 5a and distal end of the plug body.
- the non-return valve 2b may, prior to assembly, be secured to a short length of pipe or hose, the latter being secured within the end portion 4a of the socket part.
- the valve 2b may be positively centrally located within the cylindrical portion or chamber 4b to ensure that the valve does not contact the cylindrical wall of the chamber which may otherwise cause the valve to malfunction, for example, remain partially open, even when the pressure in the chamber exceeds the pressure in the hose section 2b.
- the socket body 4c may include a pair of concentric walls between which the lower end of the cylindrical portion 4b is mechanically located, and bonded or otherwise anchored in place.
- the cylindrical portion 4b may also be thicke.ned adjacent its lower end to overlie the outer of the pair of concentric walls.
- the inner concentric wall may be provided by a flange on a separate re-entrant component, bonded into the socket body 4c, which also forms the housing 4f.
- the drainage hose for surgical drains from polythene since the hose will then be relatively flexible and soft, and therefore more comfortable to the patient.
- disposal of the polythene bags gives rise to problems since polythene, when incinerated, gives off corrosive or toxic by-products.
- the hose section 2b constitutes the major proportion of the overall length of the drainage hose can be formed from polythene, whereas the relatively short hose section 2a, and therefore the bag 1,can be formed from polyvinyl chloride.
- Polyvinyl chloride can not only be disposed of by incineration without the production of toxic or corrosive by-products, but it is also a relatively cheap material to employ, and its use enables the hose section and bag assembly to be manufactured at a much higher rate.
- the connector assembly is relatively simple and foolproof to manipulate, and is relatively simple and inexpensive to manufacture and assemble since it incorporates a minimum of individual components, all or the majority of which may be readily formed, for example moulded, from synthetic plastics materials. It is economically viable for the connector assemblies to be treated as disposable items, avoiding the problensand expense of sterilization associated with re-use.
- the socket part and associated catheter may be retained connected to a patient, and used with a succession of plug parts and associated bags which are removed and disposed of when the bags are filled. When filled bags are unplugged,due to the effectively drip and void free valving arrangement, the risk of contamination being transmitted from or to the unplugged parts is effectively eliminated or significantly reduced.
- the recess 4h in the socket body 4c could be replaced or supplemented by one or more ribs with which the sleeve flarge 3f is releasably cooperable.
- Other means may be provided to ensure that, during and after removal of the plug part from the socket part, the sleeve is urged into, and/or indexed in, its closed position.
- the connector assembly is arranged with its plug part downstream of the socket part, the positions could be reversed.
- the disposition shown in the illustrated embodiment has-the advantage that the valve element 5 is assisted in closing by the normal flow of liquid through the drainage system, and the element is conveniently disposed in the chamber in the enlarged diameter socket portion 4b.
- the flap valve element 5 could, furthermore, take a form other than that of a disc valve, for example it could comprise a flexible flap valve secured or hinged at one side to the flange 4d.
- connection and disconnection of the plug and socket parts is effected simply by a manual push or pull action respectively, accompanied by a twisting action to lock or unlock the bayonet-type locking arrangement
- the locking arrangement could be omitted, or could take the form of a snap-acting connection, screw thread-type connection, or other type of releasable lock.
- the shape, configurations and materials of the various components may be changed, and the connector assembly may be applied to liquid flow systems other than surgical drainage systems.
- plug and socket parts in the illustrated embodiment are permanently secured to the hose sections, they could alternatively be press-fitted or otherwise releasably attached to the hose sections or other fluid lines, etc.
- the plug and socket bodies could be formed, for example molded, integrally with the ends of their respective fluid lines, etc.
- the diameter of the disc valve element 5 may be reduced to a value approaching that of the valve seat 4e, and may be prevented from lateral displacement relative to the valve seat to positions in which it may not fully cover the valve seat by means of upright rib-like guides within the housing 4f or on the element 5b.
- the spring 5c at its. upper end,may be located laterally, for example located in a recess in the top of the housing 4f.
- the perforate housing 4f could be replaced by a rib or equivalent mounted in the chamber in the socket part, with which the spring 5c, a sponge-like pad, or equivalent resilient element, cooperates.
- the housing or rib, and resilient element may be omitted, the disc or flap valve element relying on its own mass or resilience respectively, and/or the liquid pressure, to bias it to its closed position.
- the range of sliding movement of the sleeve may be determined by means other than the sleeve flange 3e which cooperates, alternatively, with the shoulders 3g and 3h.
- the shoulder 3h may be omitted, and instead, the flange 3e or equivalent may cooperate, with the distal end of the hose section 2a connected to the bag 1.
- the flange 4d may be omitted, and the sleeve may be permitted to project through the opening in the valve seat in the socket body 4c.
- the fully inserted position of the plug body will be determined by the bayonet-type locking arrangement or other stop means.
- the distal end of the plug body may have an annular shoulder of the same diameter as that of the seat opening and sleeve, against the underside of which the sleeve abuts in its valve-closed position.
- the transverse upper surfaces of the end wall 3b and the latter annular shoulder will be effectively flat and coplanar to ensure that, during unplugging, no voids are formed between the latter surfaces and the underside of the valve element as it closes on its seat, to avoid formation of drips.
- the drainage system may be employed with a hospitalised patient, although it could be used to advantage with a mobile patient as a urinary drain. In the latter case, since the likelihood of clots forming in the drained fluid is remote, it is not necessary to provide the pumping chamber 4b, and this may be omitted for reasons of space-and weight-saving, cost and convenience.
- the non-return valve 2d may be omitted, and the socket end portion 4a may be bonded directly to, or integrated with, the outer upper side wall of the socket body 4c.
- resilient cooperable snap-acting means may be provided to signify to a user when the plug and socket parts are fully engaged, and/or to index the sleeve in its valve-closed position during plugging or unplugging.
- the sleeve and/or plug body and/or socket body may be provided with annular ribs or other projections, and complementary cooperable grooves or depressions.
- the system for example the cylindrical socket portion 4b, may be provided with a vent or filter arrangement capable of venting gas (but not liquid)from the chamber in the event of a pressure build-up.
- a vent or filter arrangement may be incorporated in the hose section 2b or in the connection for connecting the hose section to the catheter.
- the vent arrangement may also include a portion penetrable by a syringe needle or luer to permit injection into or extraction from the arrangement.
- One or both of the non-return valves 2c, 2d may be omitted, or replaced by other types of valves.
Abstract
Description
- This invention relates to a plug-and-socket type connector assembly incorporating a cut-off valve which is intended to be substantially drip-proof in operation, the connector assembly being primarily intended to be incorporated between a surgical drain of a patient and a liquid receptacle such as a plastics bag.
- Various self-sealing connections between a drainage hose and a liquid receptacle are known, but with prior constructions liquid spillage tends to occur during the process of disconnecting the drainage hose from the receptacle, which process, in some cases, must take place several times per day. Since, in surgical drainage, the said liquid is often urine, blood or other liquid, containing pus, it will be evident that such spillage will be considered as hazardous, whether it occurs when a patient is in hospital or in private care.
- Whilst International Application No: W080/0157 and United States Patent No. 3,642,037 disclose connections which claim to avoid such spillage, these connectors are relatively complicated, and expensive to manufacture.
- It is an object of the present invention to provide a self-sealing plug-and-socket type connector assembly incorporating a cut-off valve arrangement which is not only capable of effectively eliminating spillage or dripping during connection and disconnection, but is also capable of being manufactured relatively simply and inexpensively.
- From one aspect, the present invention provides a connector assembly for use in a liquid flow system, such as a surgical drainage system, including releasably cooDerable plug and socket Darts, one of the parts incorporating a first valve and the other of the parts incorporating a second valve, operable to permit liquid to flow between the parts when plugged together, and effectively to prevent liquid spillage from the parts when unplugged, both valves being actuated by the relative plugging and unplugging movement between the plug and socket parts, the valves being arranged and adapted, during unplugging movement between the parts, to close in a manner which avoids the formation of any voids therebetween capable of accommodating sufficient liquid to form drips.
- From another aspect, the present invention provides a connector assembly for use in a liquid flow system, including releasably cooperable plug and socket parts incorporating a valve arrangement for cutting-off liquid flow through the plug and socket parts when unplugged, the plug part having a slide valve and comprising a tubular plug body closed at one end and having at least one opening near the closed end, and a sleeve surrounding the plug body, the plug body and sleeve being relatively slidable between a valve-closed position in which the sleeve closes the opening in the plug body, and a valve-open position in which the sleeve does not close the opening, the socket part comprising a tubular socket body having an open end for receiving the closed end of the plug body, and a flap valve spaced from the open end of the socket body, plugging movement between the plug and socket parts being operable both to cause displacement of the flap valve, and of the plug body and sleeve, to their valve-open positions in which a liquid path is established between the plug and socket parts via the flap valve and opening, and unplugging movement between the plug and socket parts being operable both to cause displacement of the flap valve, and of the plug body and sleeve, to their valve-closed positions whilst effectively preventing or substantially reducing dripping.
- The invention also consists in a liquid flow system incorporating one or more connector assemblies as above defined.
- The liquid flow system may comprise a surgical drainage system including a liquid receptacle, a catheter or other drain means cooperable with a patient, and a liquid line, interconnecting the drain means and receptacle, incorporating a connector assembly as above defined.
- In one embodiment, the components of the valve are integrated parts of the connecting members, i.e. the plug and socket parts, between the drainage line or hose and the receptacle or bag. The connecting action itself causes a valve to open in both the plug part and the socket part and thereby allows the passage of liquid through the system. Likewise, both valves are caused to close immediately the system is disconnected, avoiding waste from the connection or joint.
- The plug part and socket part are, respectively, welded or glued to the ends of lengths of drainage hose leading to the bag and a catheter or other drain means. The tubular plug body, which is closed by an externally planar transverse end wall at its far or distal end, is provided with side openings in its cylindrical surface or wall quite near to the end wall. The tubular sleeve is slidable lengthwise between two extreme positions, namely between valve-open and valve-closed positions. This assembly can slide into the tubular socket body of the socket part to a fully introduced position of the sleeve, the sleeve and plug body moving in unison to this position. The plug body is then advanced a small distance further, causing the sleeve to slide back relative to the plug body, to a position in which it clears the openings in the plug body and the openings communicate with the interior of the socket part. At the same time, the distal end of the plug body will lift the flap-valve at the bottom or proximal end of the socket body and thus allow a liquid to flow through the system.
- When, due to the need to exchange the bag, the plug part has to be disengaged from the socket part, the plug body, as it is being withdrawn, will initially lower the flap-valve, allowing it to close, and at the same time cause the sleeve to slide forwards and cover the openings of the plug body. These movements will follow, surface to surface,and in no situation leave empty spaces or voids for liquid. It is of great importance, apart from the function of the valve arrangement described, to achieve an economic solution, as it must be remembered, that the article is to be considered as disposable.
- In order that the invention may be more readily understood, reference will now be made to the accompanying drawings, in which:-
- Figure 1 is a schematic fragmentary side view of part of a surgical drainage system incorporating a connector assembly embodying the invention, with the plug and socket parts of the assembly partially sectioned, and shown in their disconnected, valve-closed condition; and
- Figure 2 is a view, similar to Figure 1, with the plug and socket parts shown in their interconnected, valve-open condition, on an enlarged scale.
- The surgical drainage system includes a
synthetic plastics bag 1 connected to a drainage line orhose 2a, 2b incorporating a coupling or connector assembly comprising a male orplug part 3 and a female orsocket part 4. - The plug and socket parts are formed, for example moulded, from suitable resilient, self-supporting, synthetic plastics material or materials.
- The
plug part 3 includes a tubular, cylindrical body 3a, one end of which is secured at 2e, for example by welding or gluing, within an end of thesection 2a of the drainage hose directly connected to thebag 1. The outer or distal end of the plug body 3a is closed by a transverse end wall 3b and,adjacent the end wall, the cylindrical side wall of the plug body is perforated by circumferentially extendingopenings 3c. A valve element comprising acylindrical sleeve 3d closely fits the outer cylindrical surface of the plug body. The plug body is slidable axially within thesleeve 3d from a retracted or valve-closed position as shown in Figure 1, in which the outer or distal end of the sleeve is substantially flush with the planar outer surface of the transverse end wall 3b, and the sleeve overlies and seals off theopenings 3c, to a valve-open position as shown in Figure 2, in which the distal end of the plug body 3a is advanced relative to thesleeve 3d to expose and open theopenings 3c. The proximal end of the sleeve is provided with internal and externalannular flanges internal flange 3e engages in a reduced diameter portion of the plug body, and is cooperable with stops formed byopposed shoulders 3g and 3h of the body to predetermine the range of sliding movement of the sleeve relative to the plug body. The shoulder 3h is formed at one end of anannular collar 3i integral with the plug body and formed with integral diametrically opposedpins 3k forming part of a bayonet-type locking arrangement. - The
sleeve 3d is initially assembled to the plug body 3a by pressing the flanged proximal end of the sleeve over the distal end of the plug body, and to simplify this operation, theinternal flange 3e is formed with a tapered radially inner surface to provide a lead-in. 2a - The hose section/may terminate within the
bag 1 in anon-return valve 2c (Fig. 2) which prevents liquid or gas within the bag from passing back up the hose. - The
socket part 4 is also tubular, and has a reduced diameter end portion 4a secured, for example by welding or gluing, to an end of the section 2b of drainage hose intended to be connected to a catheter or other drain. The end portion 4a communicates with one end of an enlarged diameter cylindrical/portion 4b defining a tubular chamber, the other end of the chamber communicating with atubular socket body 4c internally dimensioned to slidably receive theplug part 3. Thecylindrical portion 4b is sufficiently resilient or flexible to permit it to be compressed manually, and the hose section 2b terminates, within the chamber, in a -non-return valve 2d which prevents liquid or gas, and any bacteria etc., within the chamber from passing back up the hose section. Thenon-return valve 2d (and thevalve 2c) may be of the type which comprises a length of open-ended, flat or collapsed flexible tubing, formed, for example, from two elongate flat strips of plastics material welded together along their longer edges. - The
socket body 4c is provided, at its proximal end, with an internalannular flange 4d which serves as a stop for thesleeve 3d. The opening in theflange 4d is bounded by an annular ridge forming aseat 4e for a flap ordisc valve element 5. Thevalve element 5 includes a circular, flat elastomeric sealing disc 5a bonded or otherwise secured to the flat end face of a closed-ended cylindrical support member 5b located within the cylindrical portion orchamber 4b. Thedisc valve element 5 is displaceable, and is biased by acoil spring 5c so as normally to urge the disc 5a towards theseat 4e to close, or tend or close, the opening in theflange 4d. - The
disc valve element 5 andbias spring 5c are located in aperforate housing 4f secured to the base of the cylindrical portion orchamber 4b,with thespring 5c maintained in compression between thedisc valve element 5 and the underside of the top or end wall of thehousing 4f. The inner diameter of theflange 4d, i.e. the diameter of the opening in the flange, is approximately the same as the external diameter of the distal end region of the plug body 3a, so that the latter end region will be snugly slidably received by the flange when the plug and socket parts are connected together as shown in Figure 2. The cylindrical passage within thesocket body 4c is provided with a reduceddiameter region 4g adjacent theflange 4d, which is slightly smaller in diameter than the distal end of thesleeve 3d. Between theregion 4 and anannular recess 4h, the internal diameter of thesocket body 4c approximates or is slightly greater than the diameter of thesleeve 3d but less than the diameter of theexternal flange 3f. The distal region of the passage in thesocket body 4c, for example the region between therecess 4h and the open end of the body, may be internally stepped or tapered to provide an increased-diameter lead-in portion to facilitate insertion of thesleeve 3d. This distal region is also formed with a pair of slots 4i, forming part of the bayonet-type locking arrangement, and cooperable with thepins 3k. - The connector assembly operates as follows:-
- In the disconnected condition of the plug and
socket parts disc valve element 5 sealingly engages thevalve seat 4e on theflange 4d, preventing liquid which flows from a patient, via a catheter connected to the hose section 2b, into the chamber in thecylindrical portion 4b, from flowing out of thesocket body 4c. The distal end of the plug body 3a is retracted relative to thesleeve 3d, closing theopenings 3c so as, after use and disconnection.of thebag 1, to prevent flow of liquid from thehose section 2a connected to the bag. However, it is not essential for thesleeve 3d to close theopenings 3c of a plug part of an unused bag prior to connection. - When the
plug part 3,disposed as shown in Figure 1, is introduced into thesocket body 4c, the frictional cooperation between the plug body 3a andsleeve 3d is preferably initially greater than that between thesleeve 3d and internal surface of thesocket body 4c. Therefore, the plug body and sleeve travel together, i.e. in their valve-closed position (Figure 1),until theexternal flange 3f engages the distal end of thesocket body 4c. Further insertion of the plug part then causes the plug body to advance relative to the sleeve until the proximal end of the sleeve engages the shoulder 3h. Still further insertion of the plug part causes theflange 3f to be flexed or compressed, and the plug body and sleeve advance in unison to the position shown in Figure 2, in which theflange 3f snaps into therecess 4h, and the closed distal end of the plug body passes through theflange 4d and lifts thedisc valve element 5 from itsseat 4e against the action of thespring 5c. Thus, liquid is free to flow through the socket part, through theperforate housing 4f, through theopenings 3c, and into the plug part. This position is determined by the engagement and locking of thepins 3k in the slots 4i of the bayonet-type locking arrangement. Since, in this position, thesleeve 3d sealingly cooperates with the plug body 3a andsocket body 4c, the distal end of the sleeve engages theflange 4d and sealingly cooperates with the reduceddiameter region 4g, and the plug body is snugly received in the opening in theflange 4d, leakage between the plug and socket parts is prevented. - If due to the friction between the sleeve and plug body 3a, the sleeve does not slide back on the plug body when, during insertion, the
flange 3f engages the socket body, it will do so when its distal end encounters theregion 4g. In any event, the sleeve will be positively driven fully home against theflange 4d, and theflange 3f will be snapped into therecess 4h, by engagement of the sleeve with the shoulder 3h. - Should the liquid flowing through the system tend to block the openings in the
housing 4f and/or theopenings 3c, for example due to coagulation, the flexiblecylindrical socket portion 4b may be compressed, closing thenon-return valve 2d, to pump or force the liquid through the openings and clear the blockage. Thevalve 2d isolates the patient from contaminants and pressure buildups downstream of the valve, and thevalve 2c likewise prevents any contaminants, liquid, and pressure buildups in the bag from being transmitted to the connector assembly. - During withdrawal of the plug part from the socket part, the following procedure occurs. After the plug and socket parts have been relatively rotated to release the bayonet-type locking arrangement, the plug body 3a is firstly retracted relative to the
socket body 4c andsleeve 3d until the upper surface of its transverse end wall 3b is flush with the upper edge of thevalve seat 4e, so that the elastomeric disc 5a of thedisc valve element 5 will seat and seal on thevalve seat 4e without any significant voids, and therefore without any significant amounts of liquid being trapped, between the planar opposed surfaces of the disc 5a and distal end of the plug body. Withdrawal of the plug part alone continues since the sleeve is locked in its uppermost position by the engagement of itsflange 3f in therecess 4h, until the plug part passes down through the opening in theflange 4d and the upper surface of its transverse end wall 3b is substantially flush with the upper or distal end of thesleeve 3d, so that theopenings 3c are closed by the sleeve. In this condition, theflange 3e at the lower end of thesleeve 3d engages theshoulder 3g on the plug body, and as a result, further withdrawal of the plug body disengages theflange 3f from therecess 4h, and the sleeve and plug body (in their Figure 1 position) will be withdrawn in unison from the socket body until separated therefrom. - From the foregoing, it will be apparent that, whilst separational movement between the plug and socket parts is occurring, before the distal end of the plug body 3a is withdrawn from the opening in the
flange 4d in thesocket body 4c, thedisc valve element 5 will follow the distal end of the plug body 3a down and rest on thevalve seat 4e on theflange 4d, closing the opening therein, without at any time leaving any space between the disengaging members. Thus, separation is achieved without any dripping or other spillage or leakage. - According to a feature of the illustrated invention, the non-return valve 2b may, prior to assembly, be secured to a short length of pipe or hose, the latter being secured within the end portion 4a of the socket part. In this way, the valve 2b may be positively centrally located within the cylindrical portion or
chamber 4b to ensure that the valve does not contact the cylindrical wall of the chamber which may otherwise cause the valve to malfunction, for example, remain partially open, even when the pressure in the chamber exceeds the pressure in the hose section 2b. - In order to prevent the transparent
cylindrical portion 4b from becoming detached from thesocket body 4c when the former is manually compressed, thesocket body 4c may include a pair of concentric walls between which the lower end of thecylindrical portion 4b is mechanically located, and bonded or otherwise anchored in place. Thecylindrical portion 4b may also be thicke.ned adjacent its lower end to overlie the outer of the pair of concentric walls. The inner concentric wall may be provided by a flange on a separate re-entrant component, bonded into thesocket body 4c, which also forms thehousing 4f. - It is desirable to make the drainage hose for surgical drains from polythene since the hose will then be relatively flexible and soft, and therefore more comfortable to the patient. However, in prior drains, it is then necessary also to make the bag of polythene in order to enable the hose and bag to be readily bonded together. However, disposal of the polythene bags gives rise to problems since polythene, when incinerated, gives off corrosive or toxic by-products. In the illustrated embodiment, however, the hose section 2b constitutes the major proportion of the overall length of the drainage hose can be formed from polythene, whereas the relatively
short hose section 2a, and therefore thebag 1,can be formed from polyvinyl chloride. Polyvinyl chloride can not only be disposed of by incineration without the production of toxic or corrosive by-products, but it is also a relatively cheap material to employ, and its use enables the hose section and bag assembly to be manufactured at a much higher rate. - From the foregoing, it will be seen that there is provided a particularly advantageous form of effectively drip proof and contamination proof connector assembly. The connector assembly is relatively simple and foolproof to manipulate, and is relatively simple and inexpensive to manufacture and assemble since it incorporates a minimum of individual components, all or the majority of which may be readily formed, for example moulded, from synthetic plastics materials. It is economically viable for the connector assemblies to be treated as disposable items, avoiding the problensand expense of sterilization associated with re-use. The socket part and associated catheter may be retained connected to a patient, and used with a succession of plug parts and associated bags which are removed and disposed of when the bags are filled. When filled bags are unplugged,due to the effectively drip and void free valving arrangement, the risk of contamination being transmitted from or to the unplugged parts is effectively eliminated or significantly reduced.
- It will be understood that various modifications may be made without departing from the scope of the present invention.
- For example, the
recess 4h in thesocket body 4c could be replaced or supplemented by one or more ribs with which thesleeve flarge 3f is releasably cooperable. Other means may be provided to ensure that, during and after removal of the plug part from the socket part, the sleeve is urged into, and/or indexed in, its closed position. Although, in the specific embodiment, the connector assembly is arranged with its plug part downstream of the socket part, the positions could be reversed. The disposition shown in the illustrated embodiment, however, has-the advantage that thevalve element 5 is assisted in closing by the normal flow of liquid through the drainage system, and the element is conveniently disposed in the chamber in the enlargeddiameter socket portion 4b. Theflap valve element 5 could, furthermore, take a form other than that of a disc valve, for example it could comprise a flexible flap valve secured or hinged at one side to theflange 4d. - Although, in the illustrated embodiment, connection and disconnection of the plug and socket parts is effected simply by a manual push or pull action respectively, accompanied by a twisting action to lock or unlock the bayonet-type locking arrangement, the locking arrangement could be omitted, or could take the form of a snap-acting connection, screw thread-type connection, or other type of releasable lock.
- The shape, configurations and materials of the various components may be changed, and the connector assembly may be applied to liquid flow systems other than surgical drainage systems.
- Although the plug and socket parts in the illustrated embodiment are permanently secured to the hose sections, they could alternatively be press-fitted or otherwise releasably attached to the hose sections or other fluid lines, etc. The plug and socket bodies could be formed, for example molded, integrally with the ends of their respective fluid lines, etc.
- The diameter of the
disc valve element 5 may be reduced to a value approaching that of thevalve seat 4e, and may be prevented from lateral displacement relative to the valve seat to positions in which it may not fully cover the valve seat by means of upright rib-like guides within thehousing 4f or on the element 5b. Thespring 5c, at its. upper end,may be located laterally, for example located in a recess in the top of thehousing 4f. - The
perforate housing 4f could be replaced by a rib or equivalent mounted in the chamber in the socket part, with which thespring 5c, a sponge-like pad, or equivalent resilient element, cooperates. Alternatively, the housing or rib, and resilient element, may be omitted, the disc or flap valve element relying on its own mass or resilience respectively, and/or the liquid pressure, to bias it to its closed position. - The range of sliding movement of the sleeve may be determined by means other than the
sleeve flange 3e which cooperates, alternatively, with theshoulders 3g and 3h. For example, the shoulder 3h may be omitted, and instead, theflange 3e or equivalent may cooperate, with the distal end of thehose section 2a connected to thebag 1. - The
flange 4d may be omitted, and the sleeve may be permitted to project through the opening in the valve seat in thesocket body 4c. In this event, the fully inserted position of the plug body will be determined by the bayonet-type locking arrangement or other stop means. The distal end of the plug body may have an annular shoulder of the same diameter as that of the seat opening and sleeve, against the underside of which the sleeve abuts in its valve-closed position. The transverse upper surfaces of the end wall 3b and the latter annular shoulder will be effectively flat and coplanar to ensure that, during unplugging, no voids are formed between the latter surfaces and the underside of the valve element as it closes on its seat, to avoid formation of drips. - The drainage system may be employed with a hospitalised patient, although it could be used to advantage with a mobile patient as a urinary drain. In the latter case, since the likelihood of clots forming in the drained fluid is remote, it is not necessary to provide the
pumping chamber 4b, and this may be omitted for reasons of space-and weight-saving, cost and convenience. Thenon-return valve 2d may be omitted, and the socket end portion 4a may be bonded directly to, or integrated with, the outer upper side wall of thesocket body 4c. - In addition to, or as an alternative to, the bayonet-type locking arrangement, resilient cooperable snap-acting means may be provided to signify to a user when the plug and socket parts are fully engaged, and/or to index the sleeve in its valve-closed position during plugging or unplugging. For example the sleeve and/or plug body and/or socket body may be provided with annular ribs or other projections, and complementary cooperable grooves or depressions.
- The system, for example the
cylindrical socket portion 4b, may be provided with a vent or filter arrangement capable of venting gas (but not liquid)from the chamber in the event of a pressure build-up. Additionally or alternatively, such a vent or filter arrangement may be incorporated in the hose section 2b or in the connection for connecting the hose section to the catheter. The vent arrangement may also include a portion penetrable by a syringe needle or luer to permit injection into or extraction from the arrangement. One or both of thenon-return valves
Claims (11)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AT82306262T ATE18720T1 (en) | 1981-11-25 | 1982-11-24 | CONNECTION FOR LIQUID LINES. |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB8135609 | 1981-11-25 | ||
GB8135609 | 1981-11-25 |
Publications (2)
Publication Number | Publication Date |
---|---|
EP0080379A1 true EP0080379A1 (en) | 1983-06-01 |
EP0080379B1 EP0080379B1 (en) | 1986-03-26 |
Family
ID=10526154
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP82306262A Expired EP0080379B1 (en) | 1981-11-25 | 1982-11-24 | Connector assembly for liquid flow systems |
Country Status (12)
Country | Link |
---|---|
EP (1) | EP0080379B1 (en) |
JP (1) | JPS58109060A (en) |
AT (1) | ATE18720T1 (en) |
AU (1) | AU554339B2 (en) |
CA (1) | CA1199354A (en) |
DE (1) | DE3270165D1 (en) |
DK (1) | DK159053C (en) |
ES (1) | ES8400668A1 (en) |
FI (1) | FI77775C (en) |
NO (1) | NO152864C (en) |
NZ (1) | NZ202591A (en) |
ZA (1) | ZA828660B (en) |
Cited By (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0193697A1 (en) * | 1985-01-08 | 1986-09-10 | Astra Meditec AB | Valve-provided connecting device |
EP0198407A2 (en) * | 1985-04-12 | 1986-10-22 | Fresenius AG | Connector for peritoneal dialysis |
WO1990007953A1 (en) * | 1989-01-19 | 1990-07-26 | Dieringer Franz A | Coupling for joining flexible tubing for medical purposes |
FR2676121A1 (en) * | 1991-05-02 | 1992-11-06 | Cobe Lab | FLUID SAMPLING DEVICE. |
US5893842A (en) * | 1993-02-05 | 1999-04-13 | Becton, Dickinson And Company | Syringe needle isolation device |
WO2001043814A1 (en) * | 1999-12-17 | 2001-06-21 | Terumo Kabushiki Kaisha | Connector |
EP1210960A1 (en) * | 1993-09-16 | 2002-06-05 | Frank Richmond | Needleless valve for use in intravenous infusion |
CN110013575A (en) * | 2019-05-21 | 2019-07-16 | 史夫晓 | A kind of nursing in operating room auxiliary device |
CN113577404A (en) * | 2021-07-27 | 2021-11-02 | 首都医科大学宣武医院 | Hydrops regulation and control draw-out device |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2245881B1 (en) * | 2004-06-09 | 2007-09-16 | Joan Conejero Sugrañes | VALVE TO AUTOMATICALLY REGULATE VESICAL EMPTYING IN SUNNY SICK. |
CN102225223B (en) * | 2011-06-08 | 2013-11-20 | 北京达必通科技开发有限公司 | Three-ring injector |
Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3417750A (en) * | 1965-10-22 | 1968-12-24 | Bard Inc C R | Aspirating means and one-way valve |
GB1192986A (en) * | 1967-08-31 | 1970-05-28 | Eschmann Bros & Walsh Ltd | Intravenous Valve Assembly |
DE1950263A1 (en) * | 1968-10-08 | 1970-06-04 | Eynard & Cie J | Connection element for medical probes |
US3642037A (en) * | 1969-12-04 | 1972-02-15 | Barr Stalfort Co | Liquid transfer system |
DE2830800A1 (en) * | 1977-07-14 | 1979-02-01 | Metatech Corp | VALVE, IN PARTICULAR MINIATURE VALVE FOR MEDICAL PURPOSES |
WO1980001507A1 (en) * | 1979-01-22 | 1980-07-24 | J Svensson | Slide valve and coupler assembly |
EP0038470A1 (en) * | 1980-04-16 | 1981-10-28 | Tetra Werke Dr.rer.nat. Ulrich Baensch GmbH | Sticking connection elements for an aquarium pipe under pressure |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH337373A (en) * | 1955-12-28 | 1959-03-31 | Tetra Ag Fuer Hydraulische Bre | Coupling for hoses or pipes |
-
1982
- 1982-10-25 AU AU90881/82A patent/AU554339B2/en not_active Ceased
- 1982-11-23 FI FI824026A patent/FI77775C/en not_active IP Right Cessation
- 1982-11-24 NZ NZ202591A patent/NZ202591A/en unknown
- 1982-11-24 ES ES517639A patent/ES8400668A1/en not_active Expired
- 1982-11-24 NO NO823933A patent/NO152864C/en unknown
- 1982-11-24 CA CA000416298A patent/CA1199354A/en not_active Expired
- 1982-11-24 AT AT82306262T patent/ATE18720T1/en not_active IP Right Cessation
- 1982-11-24 DE DE8282306262T patent/DE3270165D1/en not_active Expired
- 1982-11-24 EP EP82306262A patent/EP0080379B1/en not_active Expired
- 1982-11-24 ZA ZA828660A patent/ZA828660B/en unknown
- 1982-11-25 JP JP57208362A patent/JPS58109060A/en active Pending
- 1982-11-25 DK DK524982A patent/DK159053C/en not_active IP Right Cessation
Patent Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3417750A (en) * | 1965-10-22 | 1968-12-24 | Bard Inc C R | Aspirating means and one-way valve |
GB1192986A (en) * | 1967-08-31 | 1970-05-28 | Eschmann Bros & Walsh Ltd | Intravenous Valve Assembly |
DE1950263A1 (en) * | 1968-10-08 | 1970-06-04 | Eynard & Cie J | Connection element for medical probes |
US3642037A (en) * | 1969-12-04 | 1972-02-15 | Barr Stalfort Co | Liquid transfer system |
DE2830800A1 (en) * | 1977-07-14 | 1979-02-01 | Metatech Corp | VALVE, IN PARTICULAR MINIATURE VALVE FOR MEDICAL PURPOSES |
WO1980001507A1 (en) * | 1979-01-22 | 1980-07-24 | J Svensson | Slide valve and coupler assembly |
EP0038470A1 (en) * | 1980-04-16 | 1981-10-28 | Tetra Werke Dr.rer.nat. Ulrich Baensch GmbH | Sticking connection elements for an aquarium pipe under pressure |
Cited By (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0193697A1 (en) * | 1985-01-08 | 1986-09-10 | Astra Meditec AB | Valve-provided connecting device |
US4629159A (en) * | 1985-01-08 | 1986-12-16 | Astra Meditec Ab | Valve-provided connecting device |
AU582411B2 (en) * | 1985-01-08 | 1989-03-23 | Astra-Tech Aktiebolag | Valve-provided connecting device |
EP0198407A2 (en) * | 1985-04-12 | 1986-10-22 | Fresenius AG | Connector for peritoneal dialysis |
US4745950A (en) * | 1985-04-12 | 1988-05-24 | Fresenius Ag | Connector for peritoneal dialysis |
EP0198407A3 (en) * | 1985-04-12 | 1988-06-08 | Fresenius Ag | Connector for peritoneal dialysis |
US5195994A (en) * | 1989-01-19 | 1993-03-23 | Dieringer Franz A | Coupling for joining flexible tubing for medical purposes |
WO1990007953A1 (en) * | 1989-01-19 | 1990-07-26 | Dieringer Franz A | Coupling for joining flexible tubing for medical purposes |
FR2676121A1 (en) * | 1991-05-02 | 1992-11-06 | Cobe Lab | FLUID SAMPLING DEVICE. |
US5301686A (en) * | 1991-05-02 | 1994-04-12 | Cobe Laboratories, Inc. | Fluid sampling method |
US5893842A (en) * | 1993-02-05 | 1999-04-13 | Becton, Dickinson And Company | Syringe needle isolation device |
EP1210960A1 (en) * | 1993-09-16 | 2002-06-05 | Frank Richmond | Needleless valve for use in intravenous infusion |
EP1595570A2 (en) * | 1993-09-16 | 2005-11-16 | Frank Richmond | Needleless valve for use in intravenous infusion |
EP1595570A3 (en) * | 1993-09-16 | 2006-02-08 | Frank Richmond | Needleless valve for use in intravenous infusion |
WO2001043814A1 (en) * | 1999-12-17 | 2001-06-21 | Terumo Kabushiki Kaisha | Connector |
CN110013575A (en) * | 2019-05-21 | 2019-07-16 | 史夫晓 | A kind of nursing in operating room auxiliary device |
CN110013575B (en) * | 2019-05-21 | 2021-11-09 | 宋媛媛 | Operating room nursing auxiliary device |
CN113577404A (en) * | 2021-07-27 | 2021-11-02 | 首都医科大学宣武医院 | Hydrops regulation and control draw-out device |
CN113577404B (en) * | 2021-07-27 | 2024-01-26 | 首都医科大学宣武医院 | Hydrops regulation and control extraction device |
Also Published As
Publication number | Publication date |
---|---|
DK524982A (en) | 1983-05-26 |
AU9088182A (en) | 1983-06-02 |
FI77775B (en) | 1989-01-31 |
NO152864B (en) | 1985-08-26 |
JPS58109060A (en) | 1983-06-29 |
ATE18720T1 (en) | 1986-04-15 |
NO823933L (en) | 1983-05-26 |
NZ202591A (en) | 1986-03-14 |
ES517639A0 (en) | 1983-11-01 |
NO152864C (en) | 1985-12-04 |
DK159053B (en) | 1990-08-27 |
FI824026A0 (en) | 1982-11-23 |
DK159053C (en) | 1991-01-28 |
CA1199354A (en) | 1986-01-14 |
ZA828660B (en) | 1983-07-27 |
EP0080379B1 (en) | 1986-03-26 |
FI77775C (en) | 1989-05-10 |
DE3270165D1 (en) | 1986-04-30 |
ES8400668A1 (en) | 1983-11-01 |
AU554339B2 (en) | 1986-08-14 |
FI824026L (en) | 1983-05-26 |
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