DE69940504D1 - - Google Patents
Info
- Publication number
- DE69940504D1 DE69940504D1 DE69940504T DE69940504T DE69940504D1 DE 69940504 D1 DE69940504 D1 DE 69940504D1 DE 69940504 T DE69940504 T DE 69940504T DE 69940504 T DE69940504 T DE 69940504T DE 69940504 D1 DE69940504 D1 DE 69940504D1
- Authority
- DE
- Germany
- Prior art keywords
- graft prostheses
- bioengineered graft
- prepared
- tissue material
- processed tissue
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3683—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
- A61L27/3695—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment characterised by the function or physical properties of the final product, where no specific conditions are defined to achieve this
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
- A61L27/24—Collagen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
- A61L27/3629—Intestinal tissue, e.g. small intestinal submucosa
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3641—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the site of application in the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3683—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
- A61L27/3687—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment characterised by the use of chemical agents in the treatment, e.g. specific enzymes, detergents, capping agents, crosslinkers, anticalcification agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3683—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
- A61L27/3691—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment characterised by physical conditions of the treatment, e.g. applying a compressive force to the composition, pressure cycles, ultrasonic/sonication or microwave treatment, lyophilisation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C53/00—Shaping by bending, folding, twisting, straightening or flattening; Apparatus therefor
- B29C53/36—Bending and joining, e.g. for making hollow articles
- B29C53/38—Bending and joining, e.g. for making hollow articles by bending sheets or strips at right angles to the longitudinal axis of the article being formed and joining the edges
- B29C53/40—Bending and joining, e.g. for making hollow articles by bending sheets or strips at right angles to the longitudinal axis of the article being formed and joining the edges for articles of definite length, i.e. discrete articles
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C53/00—Shaping by bending, folding, twisting, straightening or flattening; Apparatus therefor
- B29C53/56—Winding and joining, e.g. winding spirally
- B29C53/562—Winding and joining, e.g. winding spirally spirally
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US8819898P | 1998-06-05 | 1998-06-05 | |
| US12054799P | 1999-02-17 | 1999-02-17 | |
| PCT/US1999/012400 WO1999063051A2 (en) | 1998-06-05 | 1999-06-04 | Bioengineered flat sheet graft prostheses |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE69940504D1 true DE69940504D1 (de) | 2009-04-16 |
Family
ID=26778405
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69940504T Expired - Lifetime DE69940504D1 (de) | 1998-06-05 | 1999-06-04 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US7121999B2 (de) |
| EP (1) | EP1082071B1 (de) |
| JP (1) | JP4606583B2 (de) |
| AT (1) | ATE424164T1 (de) |
| AU (1) | AU754838B2 (de) |
| CA (1) | CA2334364C (de) |
| DE (1) | DE69940504D1 (de) |
| ES (1) | ES2323661T3 (de) |
| MX (1) | MXPA00012062A (de) |
| WO (1) | WO1999063051A2 (de) |
Families Citing this family (69)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6773723B1 (en) * | 2000-08-30 | 2004-08-10 | Depuy Acromed, Inc. | Collagen/polysaccharide bilayer matrix |
| EP1320390A2 (de) * | 2000-09-18 | 2003-06-25 | Organogenesis Inc. | Bioartifizielle flache schichtförmige prothesen und ihre verwendung |
| US20030033021A1 (en) * | 2001-07-16 | 2003-02-13 | Plouhar Pamela Lynn | Cartilage repair and regeneration scaffold and method |
| DK1438081T3 (da) * | 2001-10-26 | 2008-07-07 | Cook Biotech Inc | Medicinsk transplantatanordning med mesh mönstret struktur |
| US20050283256A1 (en) * | 2004-02-09 | 2005-12-22 | Codman & Shurtleff, Inc. | Collagen device and method of preparing the same |
| EP1718318B1 (de) | 2004-02-13 | 2014-08-13 | Smith & Nephew Orthopaedics AG | Zusammensetzung für wundheilung |
| FR2870450B1 (fr) * | 2004-05-18 | 2007-04-20 | David Jean Marie Nocca | Bandelette prothesique ajustable |
| EP1827527B1 (de) * | 2004-12-06 | 2016-08-24 | Cook Incorporated | Aufblasbare okklusionsvorrichtungen, verfahern und systeme |
| US20060246033A1 (en) * | 2005-03-02 | 2006-11-02 | Cook Biotech Incorporated | Injectable bulking agent compositions |
| US20100112543A1 (en) * | 2005-03-16 | 2010-05-06 | Manh-Dan Ngo | Processing soft tissue, methods and compositions related thereto |
| US7723108B2 (en) * | 2005-03-16 | 2010-05-25 | Musculoskeletal Transplant Foundation | Soft tissue processing |
| WO2006121887A2 (en) * | 2005-05-05 | 2006-11-16 | Cook Biotech Incorporated | Implantable materials and methods for inhibiting tissue adhesion formation |
| US20070014869A1 (en) * | 2005-07-15 | 2007-01-18 | Cormatrix Cardiovascular, Inc. | Compositions for reconstruction, replacement or repair of intracardiac tissue |
| US8568761B2 (en) * | 2005-07-15 | 2013-10-29 | Cormatrix Cardiovascular, Inc. | Compositions for regenerating defective or absent myocardium |
| US7429241B2 (en) * | 2005-09-29 | 2008-09-30 | Codman & Shurtleff, Inc. | Dural graft and method of preparing the same |
| CA2626014C (en) * | 2005-10-18 | 2012-07-10 | Cook Biotech Incorporated | Medical device with affixation means |
| US9364215B2 (en) * | 2006-01-26 | 2016-06-14 | Covidien Lp | Medical device package |
| US20090209031A1 (en) * | 2006-01-26 | 2009-08-20 | Tyco Healthcare Group Lp | Medical device package |
| WO2008016919A2 (en) * | 2006-07-31 | 2008-02-07 | Organogenesis Inc. | Mastopexy and breast reconstruction prostheses and method |
| CN104623643A (zh) * | 2006-10-06 | 2015-05-20 | 人类起源公司 | 天然(端肽)胎盘胶原组合物 |
| CA2604433A1 (en) * | 2006-10-06 | 2008-04-06 | Tyco Healthcare Group Lp | Medical device package including self-puncturable port |
| US7614258B2 (en) * | 2006-10-19 | 2009-11-10 | C.R. Bard, Inc. | Prosthetic repair fabric |
| US20100191346A1 (en) * | 2007-04-16 | 2010-07-29 | Stephen Bloor | Bone implant |
| WO2008125851A2 (en) * | 2007-04-16 | 2008-10-23 | Tissue Science Laboratories Plc | Vascular implant |
| AU2008237732B2 (en) * | 2007-04-16 | 2014-05-22 | Covidien Ag | Methods and compositions for tissue regeneration |
| DE102007037051A1 (de) * | 2007-07-24 | 2009-01-29 | Aesculap Ag | Flächiges Implantat |
| EP3178442A1 (de) * | 2007-12-07 | 2017-06-14 | C.R. Bard Inc. | Implantierbare prothese |
| US8257434B2 (en) | 2007-12-18 | 2012-09-04 | Cormatrix Cardiovascular, Inc. | Prosthetic tissue valve |
| US8679176B2 (en) | 2007-12-18 | 2014-03-25 | Cormatrix Cardiovascular, Inc | Prosthetic tissue valve |
| US20100318175A1 (en) * | 2007-12-31 | 2010-12-16 | C.R. Bard, Inc. | Vascular graft prosthesis with selective flow reduction |
| US9393002B2 (en) | 2008-02-18 | 2016-07-19 | Covidien Lp | Clip for implant deployment device |
| US9398944B2 (en) | 2008-02-18 | 2016-07-26 | Covidien Lp | Lock bar spring and clip for implant deployment device |
| US9301826B2 (en) | 2008-02-18 | 2016-04-05 | Covidien Lp | Lock bar spring and clip for implant deployment device |
| US9393093B2 (en) | 2008-02-18 | 2016-07-19 | Covidien Lp | Clip for implant deployment device |
| US9044235B2 (en) | 2008-02-18 | 2015-06-02 | Covidien Lp | Magnetic clip for implant deployment device |
| US9034002B2 (en) | 2008-02-18 | 2015-05-19 | Covidien Lp | Lock bar spring and clip for implant deployment device |
| US8808314B2 (en) | 2008-02-18 | 2014-08-19 | Covidien Lp | Device and method for deploying and attaching an implant to a biological tissue |
| US9833240B2 (en) | 2008-02-18 | 2017-12-05 | Covidien Lp | Lock bar spring and clip for implant deployment device |
| US8317808B2 (en) | 2008-02-18 | 2012-11-27 | Covidien Lp | Device and method for rolling and inserting a prosthetic patch into a body cavity |
| US8758373B2 (en) | 2008-02-18 | 2014-06-24 | Covidien Lp | Means and method for reversibly connecting a patch to a patch deployment device |
| EP2247245B1 (de) | 2008-02-18 | 2017-06-28 | Covidien LP | Vorrichtung zur ablage und befestigung eines pflasters auf biologischem gewebe |
| AU2009201541B2 (en) * | 2008-04-23 | 2014-12-04 | Integra Lifesciences Corporation | Flowable collagen material for dural closure |
| EP2113262B1 (de) | 2008-04-29 | 2013-11-06 | Proxy Biomedical Limited | Gewebereparaturimplantat |
| EP2792307B1 (de) | 2008-10-20 | 2017-10-04 | Covidien LP | Vorrichtung zur Anbringung eines Pflasters auf einem biologischen Gewebe |
| US8469779B1 (en) | 2009-01-02 | 2013-06-25 | Lifecell Corporation | Method for debristling animal skin |
| US20120010636A1 (en) | 2009-02-11 | 2012-01-12 | Nanyang Technological University | Multi-layered surgical prosthesis |
| US8986377B2 (en) | 2009-07-21 | 2015-03-24 | Lifecell Corporation | Graft materials for surgical breast procedures |
| EP2467066B1 (de) | 2009-08-17 | 2019-03-27 | Covidien LP | Mittel zur aufhebbaren verbindung eines implantats mit einer einsatzvorrichtung |
| WO2011021083A1 (en) | 2009-08-17 | 2011-02-24 | PolyTouch Medical, Inc. | Articulating patch deployment device and method of use |
| DE102010001271B8 (de) * | 2010-01-27 | 2012-12-06 | Urotiss Gmbh | Vernähbares Gewebetransplantatkonstrukt zur Rekonstruktion eines menschlichen oder tierischen Organs |
| US8696744B2 (en) | 2011-05-27 | 2014-04-15 | Cormatrix Cardiovascular, Inc. | Extracellular matrix material valve conduit and methods of making thereof |
| US9005275B2 (en) | 2011-11-18 | 2015-04-14 | Mayo Foundation For Medical Education And Research | Methods for replacing a circumferential segment of an esophagus |
| ES2726105T3 (es) | 2011-12-20 | 2019-10-01 | Lifecell Corp | Productos de tejido fluidizable |
| WO2013096249A1 (en) | 2011-12-20 | 2013-06-27 | Lifecell Corporation | Sheet tissue products |
| EP3400900B1 (de) | 2012-01-13 | 2020-05-20 | LifeCell Corporation | Verfahren zur herstellung von brustprothesen |
| US9271821B2 (en) | 2012-01-24 | 2016-03-01 | Lifecell Corporation | Elongated tissue matrices |
| DK3281607T3 (da) | 2012-06-21 | 2019-06-11 | Lifecell Corp | Implanterbar protese med acellulære vævsvedhæftninger. |
| US20140100648A1 (en) * | 2012-10-08 | 2014-04-10 | Robert G. Matheny | Multi-Layer Vascular Prosthesis |
| EP3659633A1 (de) | 2013-02-06 | 2020-06-03 | LifeCell Corporation | Verfahren für lokalisierte modifizierung von gewebeprodukten |
| US9238090B1 (en) | 2014-12-24 | 2016-01-19 | Fettech, Llc | Tissue-based compositions |
| JP6800888B2 (ja) | 2015-05-15 | 2020-12-16 | ライフセル コーポレーションＬｉｆｅＣｅｌｌ Ｃｏｒｐｏｒａｔｉｏｎ | 形成外科用組織マトリックス |
| EP3337427A1 (de) | 2015-08-21 | 2018-06-27 | Lifecell Corporation | Brustbehandlungsvorrichtung |
| EP3463500A1 (de) | 2016-06-03 | 2019-04-10 | LifeCell Corporation | Verfahren zur lokalisierten modifizierung von gewebeprodukten |
| EP3506854B1 (de) | 2016-08-31 | 2020-08-19 | LifeCell Corporation | Brustbehandlungsvorrichtung |
| CN107928837B (zh) * | 2017-10-23 | 2023-06-13 | 上海利格泰生物科技股份有限公司 | 用于肩袖修复的部分可吸收补片及制造方法 |
| CN111417361B (zh) | 2017-12-01 | 2023-08-11 | C·R·巴德股份有限公司 | 用于定制的内径缩小的可调节的血管移植物及相关方法 |
| WO2020227095A1 (en) | 2019-05-03 | 2020-11-12 | Lifecell Corporation | Breast treatment device |
| CN115970061A (zh) * | 2023-01-31 | 2023-04-18 | 上海卓阮医疗科技有限公司 | 用于缺乏血供场景的生物材料及其制备方法和应用 |
| CN116617471B (zh) * | 2023-07-24 | 2023-10-13 | 成都贝施美医疗科技股份有限公司 | 一种具有双层结构的口腔胶原膜及其制备方法 |
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-
1999
- 1999-06-04 WO PCT/US1999/012400 patent/WO1999063051A2/en active IP Right Grant
- 1999-06-04 DE DE69940504T patent/DE69940504D1/de not_active Expired - Lifetime
- 1999-06-04 AU AU44163/99A patent/AU754838B2/en not_active Ceased
- 1999-06-04 EP EP99927195A patent/EP1082071B1/de not_active Expired - Lifetime
- 1999-06-04 MX MXPA00012062A patent/MXPA00012062A/es not_active IP Right Cessation
- 1999-06-04 JP JP2000552247A patent/JP4606583B2/ja not_active Expired - Fee Related
- 1999-06-04 AT AT99927195T patent/ATE424164T1/de not_active IP Right Cessation
- 1999-06-04 ES ES99927195T patent/ES2323661T3/es not_active Expired - Lifetime
- 1999-06-04 CA CA2334364A patent/CA2334364C/en not_active Expired - Lifetime
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2003
- 2003-03-03 US US10/378,483 patent/US7121999B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| JP2003527137A (ja) | 2003-09-16 |
| WO1999063051A3 (en) | 2000-01-27 |
| AU4416399A (en) | 1999-12-20 |
| JP4606583B2 (ja) | 2011-01-05 |
| AU754838B2 (en) | 2002-11-28 |
| US7121999B2 (en) | 2006-10-17 |
| ES2323661T3 (es) | 2009-07-22 |
| EP1082071B1 (de) | 2009-03-04 |
| EP1082071A4 (de) | 2005-01-19 |
| MXPA00012062A (es) | 2003-04-22 |
| CA2334364C (en) | 2011-01-04 |
| CA2334364A1 (en) | 1999-12-09 |
| US20030130747A1 (en) | 2003-07-10 |
| WO1999063051A2 (en) | 1999-12-09 |
| EP1082071A2 (de) | 2001-03-14 |
| ATE424164T1 (de) | 2009-03-15 |
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