DE69935602D1 - Verabreichungssyteme für proteinarzneistoffe unter verwendung von membranmimetika - Google Patents

Verabreichungssyteme für proteinarzneistoffe unter verwendung von membranmimetika

Info

Publication number
DE69935602D1
DE69935602D1 DE69935602T DE69935602T DE69935602D1 DE 69935602 D1 DE69935602 D1 DE 69935602D1 DE 69935602 T DE69935602 T DE 69935602T DE 69935602 T DE69935602 T DE 69935602T DE 69935602 D1 DE69935602 D1 DE 69935602D1
Authority
DE
Germany
Prior art keywords
protein substances
administrative systems
membrane mimetics
mimetics
membrane
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69935602T
Other languages
English (en)
Other versions
DE69935602T2 (de
Inventor
Pankaj Modi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Generex Pharmaceuticals Inc
Original Assignee
Generex Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Generex Pharmaceuticals Inc filed Critical Generex Pharmaceuticals Inc
Publication of DE69935602D1 publication Critical patent/DE69935602D1/de
Application granted granted Critical
Publication of DE69935602T2 publication Critical patent/DE69935602T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
    • A61K9/1272—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers with substantial amounts of non-phosphatidyl, i.e. non-acylglycerophosphate, surfactants as bilayer-forming substances, e.g. cationic lipids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/28—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
DE69935602T 1998-09-27 1999-09-23 Verabreichungssyteme für proteinarzneistoffe unter verwendung von membranmimetika Expired - Lifetime DE69935602T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US161447 1998-09-27
US09/161,447 US6193997B1 (en) 1998-09-27 1998-09-27 Proteinic drug delivery system using membrane mimetics
PCT/CA1999/000879 WO2000018371A1 (en) 1998-09-27 1999-09-23 Proteinic drug delivery system using membrane mimetics

Publications (2)

Publication Number Publication Date
DE69935602D1 true DE69935602D1 (de) 2007-05-03
DE69935602T2 DE69935602T2 (de) 2007-12-06

Family

ID=22581206

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69935602T Expired - Lifetime DE69935602T2 (de) 1998-09-27 1999-09-23 Verabreichungssyteme für proteinarzneistoffe unter verwendung von membranmimetika

Country Status (14)

Country Link
US (1) US6193997B1 (de)
EP (1) EP1115381B1 (de)
JP (1) JP2002525309A (de)
AR (1) AR023055A1 (de)
AT (1) ATE357215T1 (de)
AU (1) AU749892B2 (de)
BR (1) BR9915761B1 (de)
CA (1) CA2345075A1 (de)
DE (1) DE69935602T2 (de)
DK (1) DK1115381T3 (de)
ES (1) ES2285860T3 (de)
MX (1) MXPA01003156A (de)
NZ (1) NZ510191A (de)
WO (1) WO2000018371A1 (de)

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US20030143191A1 (en) * 2001-05-25 2003-07-31 Adam Bell Chemokine beta-1 fusion proteins
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DE10214983A1 (de) * 2002-04-04 2004-04-08 TransMIT Gesellschaft für Technologietransfer mbH Vernebelbare Liposomen und ihre Verwendung zur pulmonalen Applikation von Wirkstoffen
US8435942B2 (en) * 2002-05-31 2013-05-07 Transdermal Biotechnology, Inc. Methods for formulating stabilized insulin compositions
US20040018237A1 (en) 2002-05-31 2004-01-29 Perricone Nicholas V. Topical drug delivery using phosphatidylcholine
AU2003278962B2 (en) * 2002-06-20 2006-11-23 Novartis Consumer Health S.A. Nasal compositions comprising a mucopolysaccharide and propylene glycol
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JPWO2005053643A1 (ja) * 2003-12-01 2007-06-28 三菱ウェルファーマ株式会社 リポソーム
CN1557479A (zh) * 2004-01-16 2004-12-29 深圳市海王英特龙生物技术股份有限公 干扰素脂质体乳膏
ES2318453T3 (es) * 2004-01-20 2009-05-01 Allergan, Inc. Composiciones para terapia localizada del ojo, que comprenden, de preferencia,triamcinolona acetonida y acido hialuronico.
US20050238632A1 (en) * 2004-04-23 2005-10-27 Alburty David S Propellant formulations
EP3015101B1 (de) * 2005-10-03 2019-08-21 PINSKY, Mark A. Non-phospholipid liposomen enthaltend hyaluronsäure
EP2344202B1 (de) 2008-09-08 2020-03-11 Children's Medical Center Corporation Mukosale abgabe von therapeutischen molekülen, proteinen oder teilchen, die an ceramid-lipid gekoppelt sind
DE102009031274A1 (de) 2009-06-30 2011-01-13 Justus-Liebig-Universität Giessen Liposomen zur pulmonalen Applikation
BR112012012945A2 (pt) 2009-11-25 2020-12-29 Arisgen Sa Composição de liberação mucosal, seu método de produção, complexo de peptídeo pré-formado, kit e uso de um agente ativo de peptídeo
CA2830298C (en) 2011-03-17 2016-08-16 Transdermal Biotechnology, Inc. Topical nitric oxide systems comprising lecithin and methods of use thereof
PL2794710T3 (pl) 2011-12-20 2019-02-28 Adhesys Medical Gmbh Prepolimer izocyjanianofunkcyjny do biodegradowalnego kleju tkankowego
US8871258B2 (en) 2012-09-19 2014-10-28 Transdermal Biotechnology, Inc. Treatment and prevention of learning and memory disorders
US8871261B2 (en) 2012-09-19 2014-10-28 Transdermal Biotechnology, Inc. Cancer treatments and compositions for use thereof
US8871262B2 (en) 2012-09-19 2014-10-28 Transdermal Biotechnology, Inc. Compositions and methods for treatment of osteoporosis and other indications
US8871256B2 (en) 2012-09-19 2014-10-28 Transdermal Biotechnology, Inc. Methods and systems for treatment of inflammatory diseases with nitric oxide
US8871255B2 (en) 2012-09-19 2014-10-28 Transdermal Biotechnology, Inc. Treatment of skin and soft tissue infection with nitric oxide
US8871259B2 (en) 2012-09-19 2014-10-28 Transdermal Biotechnology, Inc. Techniques and systems for treatment of neuropathic pain and other indications
US8871260B2 (en) 2012-09-19 2014-10-28 Transdermal Biotechnology, Inc. Methods and compositions for muscular and neuromuscular diseases
US8871257B2 (en) 2012-09-19 2014-10-28 Transdermal Biotechnology, Inc. Prevention and treatment of cardiovascular diseases using systems and methods for transdermal nitric oxide delivery
US8871254B2 (en) 2012-09-19 2014-10-28 Transdermal Biotechnology, Inc. Systems and methods for treatment of acne vulgaris and other conditions with a topical nitric oxide delivery system
US9687520B2 (en) 2013-03-13 2017-06-27 Transdermal Biotechnology, Inc. Memory or learning improvement using peptide and other compositions
US9387159B2 (en) 2013-03-13 2016-07-12 Transdermal Biotechnology, Inc. Treatment of skin, including aging skin, to improve appearance
US9393265B2 (en) 2013-03-13 2016-07-19 Transdermal Biotechnology, Inc. Wound healing using topical systems and methods
US9295636B2 (en) 2013-03-13 2016-03-29 Transdermal Biotechnology, Inc. Wound healing using topical systems and methods
US20140271937A1 (en) 2013-03-13 2014-09-18 Transdermal Biotechnology, Inc. Brain and neural treatments comprising peptides and other compositions
US9295647B2 (en) 2013-03-13 2016-03-29 Transdermal Biotechnology, Inc. Systems and methods for delivery of peptides
US20140271731A1 (en) 2013-03-13 2014-09-18 Transdermal Biotechnology, Inc. Cardiovascular disease treatment and prevention
US9849160B2 (en) 2013-03-13 2017-12-26 Transdermal Biotechnology, Inc. Methods and systems for treating or preventing cancer
US9320758B2 (en) 2013-03-13 2016-04-26 Transdermal Biotechnology, Inc. Brain and neural treatments comprising peptides and other compositions
US9295637B2 (en) 2013-03-13 2016-03-29 Transdermal Biotechnology, Inc. Compositions and methods for affecting mood states
US9314433B2 (en) 2013-03-13 2016-04-19 Transdermal Biotechnology, Inc. Methods and systems for treating or preventing cancer
US9314417B2 (en) 2013-03-13 2016-04-19 Transdermal Biotechnology, Inc. Treatment of skin, including aging skin, to improve appearance
US9724419B2 (en) 2013-03-13 2017-08-08 Transdermal Biotechnology, Inc. Peptide systems and methods for metabolic conditions
US9750787B2 (en) 2013-03-13 2017-09-05 Transdermal Biotechnology, Inc. Memory or learning improvement using peptide and other compositions
US20140271938A1 (en) 2013-03-13 2014-09-18 Transdermal Biotechnology, Inc. Systems and methods for delivery of peptides
US9314423B2 (en) 2013-03-13 2016-04-19 Transdermal Biotechnology, Inc. Hair treatment systems and methods using peptides and other compositions
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US9393264B2 (en) 2013-03-13 2016-07-19 Transdermal Biotechnology, Inc. Immune modulation using peptides and other compositions
US9320706B2 (en) 2013-03-13 2016-04-26 Transdermal Biotechnology, Inc. Immune modulation using peptides and other compositions
US9314422B2 (en) 2013-03-13 2016-04-19 Transdermal Biotechnology, Inc. Peptide systems and methods for metabolic conditions
US9241899B2 (en) 2013-03-13 2016-01-26 Transdermal Biotechnology, Inc. Topical systems and methods for treating sexual dysfunction
US20160151283A1 (en) * 2014-11-27 2016-06-02 Icnoderm S.R.L. Hyalurosomes, their use in topical cosmetic or pharmaceutical compositions and their preparation process
JP2021501161A (ja) 2017-10-27 2021-01-14 ザ チルドレンズ メディカル センター コーポレーション 短鎖セラミドベースの脂質およびその使用
AU2019252912A1 (en) 2018-04-12 2020-10-22 The Children's Medical Center Corporation Ceramide-like lipid-based delivery vehicles and uses thereof
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Also Published As

Publication number Publication date
BR9915761B1 (pt) 2010-12-14
US6193997B1 (en) 2001-02-27
WO2000018371A1 (en) 2000-04-06
AU749892B2 (en) 2002-07-04
MXPA01003156A (es) 2003-05-15
NZ510191A (en) 2002-09-27
JP2002525309A (ja) 2002-08-13
CA2345075A1 (en) 2000-04-06
ES2285860T3 (es) 2007-11-16
DK1115381T3 (da) 2007-07-23
BR9915761A (pt) 2001-07-24
EP1115381B1 (de) 2007-03-21
AU5843599A (en) 2000-04-17
DE69935602T2 (de) 2007-12-06
ATE357215T1 (de) 2007-04-15
AR023055A1 (es) 2002-09-04
EP1115381A1 (de) 2001-07-18

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