DE69902724D1 - Auf Energieübertragung gegründetes homogenes lumineszierendes Testverfahren - Google Patents

Auf Energieübertragung gegründetes homogenes lumineszierendes Testverfahren

Info

Publication number
DE69902724D1
DE69902724D1 DE69902724T DE69902724T DE69902724D1 DE 69902724 D1 DE69902724 D1 DE 69902724D1 DE 69902724 T DE69902724 T DE 69902724T DE 69902724 T DE69902724 T DE 69902724T DE 69902724 D1 DE69902724 D1 DE 69902724D1
Authority
DE
Germany
Prior art keywords
energy transfer
test procedure
procedure based
homogeneous luminescent
luminescent test
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69902724T
Other languages
English (en)
Other versions
DE69902724T2 (de
Inventor
Martti Latva
Ilkka Hemmilae
Kaj Blomberg
Pertti Hurskainen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wallac Oy
Original Assignee
Wallac Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wallac Oy filed Critical Wallac Oy
Application granted granted Critical
Publication of DE69902724D1 publication Critical patent/DE69902724D1/de
Publication of DE69902724T2 publication Critical patent/DE69902724T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
DE69902724T 1998-07-17 1999-06-03 Auf Energieübertragung gegründetes homogenes lumineszierendes Testverfahren Expired - Lifetime DE69902724T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US09/116,763 US5998146A (en) 1998-07-17 1998-07-17 Homogeneous luminescence assay method based on energy transfer

Publications (2)

Publication Number Publication Date
DE69902724D1 true DE69902724D1 (de) 2002-10-10
DE69902724T2 DE69902724T2 (de) 2003-01-09

Family

ID=22369056

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69902724T Expired - Lifetime DE69902724T2 (de) 1998-07-17 1999-06-03 Auf Energieübertragung gegründetes homogenes lumineszierendes Testverfahren

Country Status (4)

Country Link
US (1) US5998146A (de)
EP (1) EP0973036B1 (de)
DE (1) DE69902724T2 (de)
ES (1) ES2180263T3 (de)

Families Citing this family (52)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9811483D0 (en) * 1998-05-29 1998-07-29 Photonic Research Systems Limi Luminescence assay using cyclical excitation wavelength sequence
US6441152B1 (en) * 1998-12-08 2002-08-27 Boston Probes, Inc. Methods, kits and compositions for the identification of nucleic acids electrostatically bound to matrices
EP1305412A2 (de) 1999-10-14 2003-05-02 Clontech Laboratories Inc. Chromo/fluoroproteine aus anthozoa und verwendung der gleichen
FI20000333A0 (fi) * 2000-02-16 2000-02-16 Jussi Nurmi Homogeeninen menetelmä polynukleotidin havaitsemiseksi
US6844154B2 (en) 2000-04-04 2005-01-18 Polygenyx, Inc. High throughput methods for haplotyping
ES2245995T3 (es) * 2000-11-16 2006-02-01 F. Hoffmann-La Roche Ag Pares de colorantes para mediciones de transferencia de energia de fluorescencia-resonancia (fret).
WO2003003063A2 (en) * 2001-06-28 2003-01-09 Ia, Inc. Fiber-optic sensor array
US9261460B2 (en) 2002-03-12 2016-02-16 Enzo Life Sciences, Inc. Real-time nucleic acid detection processes and compositions
US6760104B2 (en) 2001-07-20 2004-07-06 Grigoriy Gomelskiy Apparatus, method, and system for analyzing samples using triboluminescent technology
DE10137530A1 (de) * 2001-08-01 2003-02-13 Presens Prec Sensing Gmbh Anordnung und Verfahren zur Mehrfach-Fluoreszenzmessung
DE10153829A1 (de) 2001-11-05 2003-05-28 Bayer Ag Assay basierend auf dotierten Nanoteilchen
DE10159579A1 (de) * 2001-12-05 2003-06-18 Applera Deutschland Gmbh Heterogenes Lumineszenz-Nachweisverfahren in Kavitätenstrukturen
ATE439368T1 (de) * 2001-12-19 2009-08-15 Univ Chicago Schnellreifende fluoreszierende proteine und verfahren zu deren anwendung
US7371582B2 (en) * 2002-01-23 2008-05-13 Boditechmed Inc. Lateral flow quantitative assay method and strip and laser-induced fluorescence detection device therefor
US9353405B2 (en) 2002-03-12 2016-05-31 Enzo Life Sciences, Inc. Optimized real time nucleic acid detection processes
US20030232394A1 (en) * 2002-06-12 2003-12-18 Aventis Pharma Deutschland Gmbh High throughput screening method and assay system for determining the interaction between C-reactive protein and components binding to it
RU2221236C1 (ru) * 2002-09-16 2004-01-10 Калачев Алексей Александрович Способ анализа физических и/или химических свойств поверхностного слоя твердого тела (варианты)
AU2003285844A1 (en) 2002-11-12 2004-06-03 Zakrytoe Aktsionernoe Obschestvo "Evrogen" Fluorescent proteins and chromoproteins from non-aequorea hydrozoa species and methods for using same
DE10259677B4 (de) * 2002-12-18 2008-01-24 Büddefeld, Jürgen, Prof. Dr.-Ing. Sonden zum Nachweis von Nukleinsäuren, insbesondere zum Nachweis pathogener Keime in Lebensmitteln
RU2345137C2 (ru) 2002-12-26 2009-01-27 Закрытое акционерное общество "ЕВРОГЕН" Флуоресцирующие белки из веслоногих ракообразных и способы их применения
FI20030460A0 (fi) * 2003-03-28 2003-03-28 Tero Soukka Homogeeninen määritysmenetelmä, joka perustuu luminesenssienergiasiirtoon
GB0311948D0 (en) * 2003-05-23 2003-06-25 Stockport Innovation Ltd Light emitting probes
US7727752B2 (en) 2003-07-29 2010-06-01 Life Technologies Corporation Kinase and phosphatase assays
EP1673634B1 (de) * 2003-10-01 2008-08-06 Wallac Oy Verbesserter homogenener zeitaufgelöster energietransfertest
WO2005100387A1 (en) * 2004-04-07 2005-10-27 The University Of Chicago Monomeric red fluorescent proteins
US20060147954A1 (en) * 2004-10-19 2006-07-06 Wallac Oy Novel probe and its use in bioaffinity assays
DE112005002636T5 (de) * 2004-10-22 2007-09-06 Wallac Oy Hochempfindliche homogene Analyse auf der Grundlage einer FRET-Messung mit Anti-Stokes-Verschiebung
RU2412250C2 (ru) * 2005-11-04 2011-02-20 Закрытое акционерное общество "ЕВРОГЕН" Модифицированные зеленые флуоресцентные белки и способы их использования
EP1994149B1 (de) 2006-01-25 2010-09-29 Evrogen IP Neue fluoreszenzproteine und verfahren zur verwendung davon
US8563703B2 (en) 2006-01-25 2013-10-22 Evrogen IP Joint Stock Company Fluorescent proteins and methods for using same
CA2659251C (en) 2006-07-10 2016-06-14 The Regents Of The University Of California Luminescent 1-hydroxy-2-pyridinone chelates of lanthanides
ES2655082T3 (es) 2006-08-15 2018-02-16 The Regents Of The University Of California Complejos luminiscentes de lantánidos macrocíclicos
US8680235B2 (en) * 2006-09-22 2014-03-25 Stowers Institute For Medical Research Branchiostoma derived fluorescent proteins
US9146233B2 (en) * 2006-11-13 2015-09-29 Perkinelmer Health Sciences, Inc. Detecting molecular interactions by fluorescence resonance energy transfer on a solid-phase support
US8507199B2 (en) 2007-01-25 2013-08-13 Lumiphore, Inc. Multi-color time resolved fluorophores based on macrocyclic lanthanide complexes
EP2169404B1 (de) * 2007-06-18 2016-01-27 Chugai Seiyaku Kabushiki Kaisha VERFAHREN ZUR MESSUNG DER BINDUNGSAKTIVITÄT EINES ANTIKÖRPERS MIT EINEM ANTIGEN UND MIT EINEM Fc-REZEPTOR
WO2009059305A2 (en) * 2007-11-01 2009-05-07 The University Of Chicago Red fluorescent proteins with enhanced bacterial expression, increased brightness and reduced aggregation
FI20070926A0 (fi) * 2007-11-30 2007-11-30 Wallac Oy Transportterimääritys
WO2009134897A1 (en) * 2008-04-29 2009-11-05 Burnham Institute For Medical Research E3-independent ubiquitinylation assay
DE102008033871A1 (de) * 2008-06-26 2009-12-31 InBio Prof.Jürgen Büddefeld Dr.Peter Klauth Prof.Manfred Rietz GbR (vertretungsberechtigter Gesellschafter: Dr.Peter Klauth, 41189 Mönchengladbach) Abstandsgesteuerte Energietransfer-Farbstoffkomplexe
WO2011025790A1 (en) 2009-08-24 2011-03-03 Lumiphore, Inc. Macrocyclic hopo chelators
FI20090306A0 (fi) 2009-08-25 2009-08-25 Qret Technologies Oy Erotusvapaa määritysmenetelmä
EP2516407A4 (de) * 2009-12-24 2013-06-12 Lumiphore Inc Radiopharmazeutische komplexe
US8834846B2 (en) 2010-05-06 2014-09-16 Bruker Biospin Corporation Fluorescent NIRF activatable probes for disease detection
EP2598649A1 (de) * 2010-07-31 2013-06-05 Advanced Biomedical Limited Verfahren, reagens und vorrichtung zur erfassung eines chemischen chelatbildners
JP6043288B2 (ja) 2010-09-15 2016-12-14 エンダセア， インコーポレイテッド 時間分解蛍光ベースのアッセイによるリポ多糖の測定のための使用方法およびキット
US11453652B2 (en) 2013-03-15 2022-09-27 Lumiphore, Inc. Di-macrocycles
CN104181310A (zh) * 2014-07-30 2014-12-03 美艾利尔（上海）诊断产品有限公司 一种检测β-hCG含量的时间分辨免疫荧光试剂盒及其制备方法和应用
CN107810420B (zh) 2015-06-25 2020-08-14 豪夫迈·罗氏有限公司 用于测定抗体或配体结合和功能的基于细胞的测定
JP7215999B2 (ja) 2016-12-21 2023-01-31 エフ．ホフマン－ラ ロシュ アーゲー 抗体またはリガンドの結合および機能を決定するためのアッセイ法
FI130554B (en) 2020-01-20 2023-11-16 Oy Arctic Partners Ab LUMINESCENCE HYBRIDIZATION DETERMINATION METHOD
CN112946272B (zh) * 2021-01-28 2021-12-24 无锡壹闪生物科技有限公司 一种核基质蛋白22的快速检测试剂盒及其应用

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4594179A (en) * 1984-08-01 1986-06-10 The United States Of America As Represented By The United States Department Of Energy Reduction of reabsorption effects in scintillators by employing solutes with large Stokes shifts
US4822733A (en) * 1985-05-28 1989-04-18 Amoco Corporation Lifetime-resolved assay procedures
US5279943A (en) * 1985-08-02 1994-01-18 Compagnie Oris Industrie Homogeneous process for the detection and/or determination by luminescence of an analyte in a medium in which it may be present
US4868103A (en) * 1986-02-19 1989-09-19 Enzo Biochem, Inc. Analyte detection by means of energy transfer
EP0272320B1 (de) * 1986-06-17 1994-03-23 Baxter Diagnostics Inc. Homogenes fluortestverfahren mit abstoss des fluorzenten hintergrundes.
GB8820887D0 (en) * 1988-09-06 1988-10-05 Atomic Energy Authority Uk Detecting selected species
CA2033692A1 (en) * 1990-01-25 1991-07-26 Wilhelm Bannwarth Energy transfer systems
FR2664699B1 (fr) * 1990-07-13 1995-08-18 Cis Bio Int Procede d'amplification du signal d'emission d'un compose luminescent.
EP0552108B1 (de) * 1992-01-17 1999-11-10 Lakowicz, Joseph R. Phasenmodulationsenergieübertragungsfluoroimmunassay
US5622821A (en) * 1994-06-29 1997-04-22 The Regents Of The University Of California Luminescent lanthanide chelates and methods of use
US5661035A (en) * 1995-06-07 1997-08-26 The Regents Of The University Of California Voltage sensing by fluorescence resonance energy transfer
FI963989A (fi) * 1996-10-04 1998-04-05 Wallac Oy Homogeenisiä määritysmenetelmiä, jotka perustuvat luminesenssienergiasiirtoon

Also Published As

Publication number Publication date
ES2180263T3 (es) 2003-02-01
EP0973036A3 (de) 2000-03-08
EP0973036A2 (de) 2000-01-19
DE69902724T2 (de) 2003-01-09
US5998146A (en) 1999-12-07
EP0973036B1 (de) 2002-09-04

Similar Documents

Publication Publication Date Title
DE69902724T2 (de) Auf Energieübertragung gegründetes homogenes lumineszierendes Testverfahren
DE69830854D1 (de) Mehrfaches testverfahren
DE69933553D1 (de) Elektronischer batterietester
DE69808753D1 (de) Mehrfachübertragungsvermittlung und -verfahren
DE69808432T2 (de) Transfereinrichtung
DE69816532D1 (de) Wärmeübergangsstruktur
NO20003761D0 (no) Varmeoverføringsanordning
SE9803983D0 (sv) An antenna device
DE69941322D1 (de) Verbindungstestverfahren
DE60030391D1 (de) Halbleiterschaltung mit Prüfungsfähigkeit
ID28840A (id) Pengujian
NL1006747A1 (nl) Overslaginrichting.
DE29815433U1 (de) Versetzgerät
IS5213A (is) Þvagrásartæki
DE29810978U1 (de) Prüfleck
DE59904852D1 (de) Integrierte schaltung mit scan-register-kette
DE29715907U1 (de) Koppelvorrichtung für eine Energieführungskette
DE69942340D1 (de) Hochenergie elektronen beugungsgerät
FR2771853B1 (fr) Plot de test de circuit integre
DE29603333U1 (de) Elektronischer Energiezähler
DE29812115U1 (de) Übergabegerät
DE29809027U1 (de) Heizkreisrohrgruppe
DE69924566D1 (de) Heizungsvorrichtung
IS5271A (is) Þvagrásartæki
DE29821182U1 (de) Dichtheitsprüfgerät

Legal Events

Date Code Title Description
8364 No opposition during term of opposition