DE69900714T2 - Verfahren und vorrichtung zur laminaren strömung an einer sensoroberfläche - Google Patents
Verfahren und vorrichtung zur laminaren strömung an einer sensoroberflächeInfo
- Publication number
- DE69900714T2 DE69900714T2 DE69900714T DE69900714T DE69900714T2 DE 69900714 T2 DE69900714 T2 DE 69900714T2 DE 69900714 T DE69900714 T DE 69900714T DE 69900714 T DE69900714 T DE 69900714T DE 69900714 T2 DE69900714 T2 DE 69900714T2
- Authority
- DE
- Germany
- Prior art keywords
- sensor surface
- laminary flow
- laminary
- flow
- sensor
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/55—Specular reflectivity
- G01N21/552—Attenuated total reflection
- G01N21/553—Attenuated total reflection and using surface plasmons
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502769—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements
- B01L3/502776—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements specially adapted for focusing or laminating flows
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y30/00—Nanotechnology for materials or surface science, e.g. nanocomposites
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/01—Arrangements or apparatus for facilitating the optical investigation
- G01N21/03—Cuvette constructions
- G01N21/05—Flow-through cuvettes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/645—Specially adapted constructive features of fluorimeters
- G01N21/648—Specially adapted constructive features of fluorimeters using evanescent coupling or surface plasmon coupling for the excitation of fluorescence
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00497—Features relating to the solid phase supports
- B01J2219/00511—Walls of reactor vessels
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/0054—Means for coding or tagging the apparatus or the reagents
- B01J2219/00572—Chemical means
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00585—Parallel processes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00596—Solid-phase processes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
- B01J2219/00623—Immobilisation or binding
- B01J2219/0063—Other, e.g. van der Waals forces, hydrogen bonding
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
- B01J2219/00632—Introduction of reactive groups to the surface
- B01J2219/00637—Introduction of reactive groups to the surface by coating it with another layer
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00657—One-dimensional arrays
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00659—Two-dimensional arrays
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00675—In-situ synthesis on the substrate
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00718—Type of compounds synthesised
- B01J2219/0072—Organic compounds
- B01J2219/00722—Nucleotides
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00718—Type of compounds synthesised
- B01J2219/0072—Organic compounds
- B01J2219/00725—Peptides
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00718—Type of compounds synthesised
- B01J2219/0072—Organic compounds
- B01J2219/00734—Lipids
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/06—Fluid handling related problems
- B01L2200/0636—Focussing flows, e.g. to laminate flows
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/12—Specific details about manufacturing devices
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/06—Auxiliary integrated devices, integrated components
- B01L2300/0627—Sensor or part of a sensor is integrated
- B01L2300/0636—Integrated biosensor, microarrays
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
- B01L2300/0877—Flow chambers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/01—Arrangements or apparatus for facilitating the optical investigation
- G01N21/03—Cuvette constructions
- G01N2021/0346—Capillary cells; Microcells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/01—Arrangements or apparatus for facilitating the optical investigation
- G01N21/03—Cuvette constructions
- G01N21/05—Flow-through cuvettes
- G01N2021/058—Flat flow cell
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S366/00—Agitating
- Y10S366/01—Micromixers: continuous laminar flow with laminar boundary mixing in the linear direction parallel to the fluid propagation with or without conduit geometry influences from the pathway
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S366/00—Agitating
- Y10S366/03—Micromixers: variable geometry from the pathway influences mixing/agitation of non-laminar fluid flow
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/11—Automated chemical analysis
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/11—Automated chemical analysis
- Y10T436/117497—Automated chemical analysis with a continuously flowing sample or carrier stream
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
- Y10T436/25625—Dilution
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
- Y10T436/2575—Volumetric liquid transfer
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Engineering & Computer Science (AREA)
- Nanotechnology (AREA)
- Clinical Laboratory Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Hematology (AREA)
- Composite Materials (AREA)
- Condensed Matter Physics & Semiconductors (AREA)
- Materials Engineering (AREA)
- Crystallography & Structural Chemistry (AREA)
- Dispersion Chemistry (AREA)
- Optical Measuring Cells (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/009,139 US6200814B1 (en) | 1998-01-20 | 1998-01-20 | Method and device for laminar flow on a sensing surface |
PCT/SE1999/000063 WO1999036766A1 (en) | 1998-01-20 | 1999-01-19 | Method and device for laminar flow on a sensing surface |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69900714D1 DE69900714D1 (de) | 2002-02-21 |
DE69900714T2 true DE69900714T2 (de) | 2002-06-27 |
Family
ID=21735806
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69900714T Expired - Lifetime DE69900714T2 (de) | 1998-01-20 | 1999-01-19 | Verfahren und vorrichtung zur laminaren strömung an einer sensoroberfläche |
Country Status (5)
Country | Link |
---|---|
US (6) | US6200814B1 (de) |
EP (1) | EP1021703B1 (de) |
JP (1) | JP4340766B2 (de) |
DE (1) | DE69900714T2 (de) |
WO (1) | WO1999036766A1 (de) |
Families Citing this family (159)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE69737883T2 (de) | 1996-04-25 | 2008-03-06 | Bioarray Solutions Ltd. | Licht-regulierte, elektrokinetische zusammensetzung von partikeln an oberflächen |
US6200814B1 (en) * | 1998-01-20 | 2001-03-13 | Biacore Ab | Method and device for laminar flow on a sensing surface |
US6937341B1 (en) | 1998-09-29 | 2005-08-30 | J. A. Woollam Co. Inc. | System and method enabling simultaneous investigation of sample with two beams of electromagnetic radiation |
EP1117991A4 (de) | 1998-10-02 | 2005-04-27 | California Inst Of Techn | Organische leitende sensoren, sensormatrix und verfahren zu ihrer gebrauch |
FR2790092B1 (fr) * | 1999-02-24 | 2001-03-30 | Commissariat Energie Atomique | Procede de determination d'un analyte present dans une solution |
US7122152B2 (en) * | 1999-05-10 | 2006-10-17 | University Of Florida | Spatiotemporal and geometric optimization of sensor arrays for detecting analytes fluids |
EP1192454B1 (de) | 1999-05-10 | 2006-03-01 | California Institute of Technology | Verwendung eines räumlich-zeitlichen reaktionsverhaltens in sensor-arrays zur detektion von analyten in fluiden |
US6631333B1 (en) * | 1999-05-10 | 2003-10-07 | California Institute Of Technology | Methods for remote characterization of an odor |
US6771376B2 (en) * | 1999-07-05 | 2004-08-03 | Novartis Ag | Sensor platform, apparatus incorporating the platform, and process using the platform |
JP4684507B2 (ja) | 1999-07-05 | 2011-05-18 | ノバルティス アーゲー | センサープラットホームを使用する方法 |
WO2001013096A1 (de) * | 1999-08-13 | 2001-02-22 | Zeptosens Ag | Vorrichtung und verfahren zur multianalytbestimmung |
US6696022B1 (en) | 1999-08-13 | 2004-02-24 | U.S. Genomics, Inc. | Methods and apparatuses for stretching polymers |
US6890715B1 (en) * | 1999-08-18 | 2005-05-10 | The California Institute Of Technology | Sensors of conducting and insulating composites |
US7167615B1 (en) | 1999-11-05 | 2007-01-23 | Board Of Regents, The University Of Texas System | Resonant waveguide-grating filters and sensors and methods for making and using same |
US6432290B1 (en) | 1999-11-26 | 2002-08-13 | The Governors Of The University Of Alberta | Apparatus and method for trapping bead based reagents within microfluidic analysis systems |
CA2290731A1 (en) | 1999-11-26 | 2001-05-26 | D. Jed Harrison | Apparatus and method for trapping bead based reagents within microfluidic analysis system |
US7349092B1 (en) | 2000-02-22 | 2008-03-25 | J.A. Woollam Co., Inc | System for reducing stress induced effects during determination of fluid optical constants |
EP1281047A4 (de) * | 2000-04-24 | 2004-03-24 | Nathan S Lewis | Raumzeitliche und geometrische optimierung von sensor-arrays zur erkennung von analyten in fluiden |
JP4744778B2 (ja) | 2000-06-21 | 2011-08-10 | バイオアレイ ソルーションズ リミテッド | 特定のランダム粒子アレイを適用した複数の被検体分子の分析方法 |
US9709559B2 (en) | 2000-06-21 | 2017-07-18 | Bioarray Solutions, Ltd. | Multianalyte molecular analysis using application-specific random particle arrays |
US20010055546A1 (en) * | 2000-06-23 | 2001-12-27 | Weigl Bernhard H. | Method and apparatus for controlling fluid flow rate in a microfluidic circuit |
GB0016247D0 (en) * | 2000-06-30 | 2000-08-23 | Torsana Biosensor Diagnostics | Flow cell assemblies and methods of spatially directed interaction between liquids and solid surfaces |
US7126688B2 (en) * | 2000-07-11 | 2006-10-24 | Maven Technologies, Llc | Microarray scanning |
US6833920B2 (en) | 2000-07-11 | 2004-12-21 | Maven Technologies Llc | Apparatus and method for imaging |
US7193711B2 (en) * | 2000-07-11 | 2007-03-20 | Maven Technologies, Llc | Imaging method and apparatus |
US6594011B1 (en) | 2000-07-11 | 2003-07-15 | Maven Technologies, Llc | Imaging apparatus and method |
US7518724B2 (en) * | 2000-07-11 | 2009-04-14 | Maven Technologies | Image acquisition, processing, and display |
US7023547B2 (en) | 2000-07-11 | 2006-04-04 | Maven Technologies, Llc | Apparatus including a biochip for imaging of biological samples and method |
US7223363B2 (en) * | 2001-03-09 | 2007-05-29 | Biomicro Systems, Inc. | Method and system for microfluidic interfacing to arrays |
SE0100889D0 (sv) | 2001-03-14 | 2001-03-14 | Biacore Ab | Method and apparatus for attenuated total reflection spectrosopy |
SE0100875D0 (sv) * | 2001-03-14 | 2001-03-14 | Biacore Ab | Method of preparing supported lipid film membranes and use thereof |
US7179659B2 (en) * | 2001-04-02 | 2007-02-20 | Agilent Technologies, Inc. | Sensor surfaces for detecting analytes and methods of use |
AU2002258702A1 (en) * | 2001-04-02 | 2002-10-15 | Prolinx Incorporated | Systems and apparatus for the analysis of molecular interactions |
US7314718B1 (en) * | 2001-04-03 | 2008-01-01 | Bioarray Solutions Ltd. | Method and apparatus for maintaining multiple planar fluid flows |
US7262063B2 (en) | 2001-06-21 | 2007-08-28 | Bio Array Solutions, Ltd. | Directed assembly of functional heterostructures |
AU2002345465B2 (en) * | 2001-06-29 | 2007-04-26 | Ge Healthcare Bio-Sciences Ab | Flow cell method |
SE0102331D0 (sv) * | 2001-06-29 | 2001-06-29 | Biacore Ab | Flow cell method |
WO2003014711A1 (fr) * | 2001-08-07 | 2003-02-20 | Mitsubishi Chemical Corporation | Puce de detection a resonance de plasmon de surface et procede et dispositif d'analyse d'echantillon utilisant cette puce |
JP4377689B2 (ja) | 2001-10-15 | 2009-12-02 | バイオアレイ ソリューションズ リミテッド | 同時尋問及び酵素仲介検出による多型遺伝子座の複合分析 |
US20030082632A1 (en) * | 2001-10-25 | 2003-05-01 | Cytoprint, Inc. | Assay method and apparatus |
US20040028559A1 (en) * | 2001-11-06 | 2004-02-12 | Peter Schuck | Sample delivery system with laminar mixing for microvolume biosensing |
US20030157586A1 (en) * | 2002-02-21 | 2003-08-21 | Martin Bonde | Device and method for conducting cellular assays using multiple fluid flow |
US7560267B2 (en) * | 2002-03-18 | 2009-07-14 | City University Of Hong Kong | Apparatus and methods for on-chip monitoring of cellular reactions |
US7112444B2 (en) * | 2002-04-24 | 2006-09-26 | Wisconsin Alumni Research Foundation | Method of performing gradient-based assays in a microfluidic device |
US20060127278A1 (en) * | 2002-04-26 | 2006-06-15 | Gast Alice P | System and method of measuring molecular interactions |
DE10222334A1 (de) * | 2002-05-18 | 2003-12-04 | Leica Microsystems | Vorrichtung zum Einbringen einer Probe in ein Durchfluss-Analysensystem |
WO2003102580A1 (en) | 2002-05-31 | 2003-12-11 | Biacore Ab | Method of coupling binding agents to a substrate surface |
AU2003276870A1 (en) * | 2002-09-07 | 2004-03-29 | Lightwave Bioapplications | Bioanalysis systems including optical integrated circuit |
JP2004113874A (ja) * | 2002-09-24 | 2004-04-15 | National Institute Of Advanced Industrial & Technology | マイクロ流路利用反応方法 |
AU2003287236A1 (en) * | 2002-10-31 | 2004-06-07 | Luna Innovations, Inc. | Fiber-optic flow cell and method relating thereto |
AU2003298655A1 (en) | 2002-11-15 | 2004-06-15 | Bioarray Solutions, Ltd. | Analysis, secure access to, and transmission of array images |
US20050150778A1 (en) * | 2002-11-18 | 2005-07-14 | Lewis Nathan S. | Use of basic polymers in carbon black composite vapor detectors to obtain enhanced sensitivity and classification performance for volatile fatty acids |
EP1594694A4 (de) | 2002-12-30 | 2010-01-20 | Univ California | Verfahren und vorrichtung zum nachweis und zur analyse von krankheitserregern |
US7655477B1 (en) * | 2003-02-26 | 2010-02-02 | Science Applications International Corporation | System and method for the separation of analytes |
ATE510605T1 (de) * | 2003-03-14 | 2011-06-15 | Univ Columbia | Systeme und verfahren für auf blut basierende therapien mit einer membranlosen mikrofluid- austauschvorrichtung |
US20060076295A1 (en) | 2004-03-15 | 2006-04-13 | The Trustees Of Columbia University In The City Of New York | Systems and methods of blood-based therapies having a microfluidic membraneless exchange device |
NZ580449A (en) * | 2003-09-11 | 2011-06-30 | Theranos Inc | Ingestible medical device with biocompatible polymer coating, device with microarray to interact with disease marker |
WO2005029705A2 (en) | 2003-09-18 | 2005-03-31 | Bioarray Solutions, Ltd. | Number coding for identification of subtypes of coded types of solid phase carriers |
NZ546072A (en) | 2003-09-22 | 2009-08-28 | Bioarray Solutions Ltd | Surface immobilized polyelectrolyte with multiple functional groups capable of covalently bonding to biomolecules |
WO2005042763A2 (en) | 2003-10-28 | 2005-05-12 | Bioarray Solutions Ltd. | Optimization of gene expression analysis using immobilized capture probes |
EP1694859B1 (de) | 2003-10-29 | 2015-01-07 | Bioarray Solutions Ltd | Multiplex-nukleinsäureanalyse mittels fragmentierung doppelsträngiger dna |
JP4341372B2 (ja) * | 2003-10-30 | 2009-10-07 | コニカミノルタホールディングス株式会社 | 液体の混合方法および混合装置ならびに混合システム |
US7396512B2 (en) * | 2003-11-04 | 2008-07-08 | Drummond Scientific Company | Automatic precision non-contact open-loop fluid dispensing |
EP1682261B1 (de) * | 2003-11-12 | 2012-08-15 | BIO-RAD Haifa Ltd. | Verfahren zur durchführung mehrerer bindungsreaktionen in arrayformat |
WO2005049582A1 (en) * | 2003-11-14 | 2005-06-02 | Auspex Pharmaceuticals, Inc. | Method of preparation of novel nucleoside analogs and uses |
SE0303319D0 (sv) | 2003-12-10 | 2003-12-10 | Biacore Ab | Sample flow positioning method and analytical system using the method |
JP4870571B2 (ja) * | 2003-12-10 | 2012-02-08 | ジーイー・ヘルスケア・バイオサイエンス・アクチボラグ | サンプルの流れの位置決め法及び該方法を用いた分析システム |
JP4632400B2 (ja) * | 2003-12-16 | 2011-02-16 | キヤノン株式会社 | 細胞培養用基板、その製造方法、それを用いた細胞スクリーニング法 |
GB0329220D0 (en) * | 2003-12-17 | 2004-01-21 | Inverness Medical Switzerland | System |
WO2005086703A2 (en) * | 2004-03-05 | 2005-09-22 | Creatv Microtech, Inc. | Flow-through chemical and biological sensor |
US7799553B2 (en) | 2004-06-01 | 2010-09-21 | The Regents Of The University Of California | Microfabricated integrated DNA analysis system |
US7848889B2 (en) | 2004-08-02 | 2010-12-07 | Bioarray Solutions, Ltd. | Automated analysis of multiplexed probe-target interaction patterns: pattern matching and allele identification |
CN101073002B (zh) | 2004-09-15 | 2012-08-08 | 英特基因有限公司 | 微流体装置 |
WO2006047591A2 (en) * | 2004-10-25 | 2006-05-04 | University Of Washington | Rapid microfluidic assay for analyte interactions |
US7285420B2 (en) * | 2004-11-18 | 2007-10-23 | Corning Incorporated | System and method for self-referencing a sensor in a micron-sized deep flow chamber |
DE102005018337A1 (de) * | 2005-04-20 | 2006-11-02 | Micronas Gmbh | Mikrooptisches Detektionssystem und Verfahren zur Bestimmung temperaturabhängiger Parameter von Analyten |
CA2505657A1 (en) * | 2005-04-28 | 2006-10-28 | York University | Method for mixing inside a capillary and device for achieving same |
US7300631B2 (en) | 2005-05-02 | 2007-11-27 | Bioscale, Inc. | Method and apparatus for detection of analyte using a flexural plate wave device and magnetic particles |
US7611908B2 (en) * | 2005-05-02 | 2009-11-03 | Bioscale, Inc. | Method and apparatus for therapeutic drug monitoring using an acoustic device |
US7749445B2 (en) * | 2005-05-02 | 2010-07-06 | Bioscale, Inc. | Method and apparatus for analyzing bioprocess fluids |
US7648844B2 (en) * | 2005-05-02 | 2010-01-19 | Bioscale, Inc. | Method and apparatus for detection of analyte using an acoustic device |
KR101762424B1 (ko) * | 2005-05-09 | 2017-07-28 | 테라노스, 인코포레이티드 | 현장진료 유체 시스템 및 그 용도 |
US8486629B2 (en) | 2005-06-01 | 2013-07-16 | Bioarray Solutions, Ltd. | Creation of functionalized microparticle libraries by oligonucleotide ligation or elongation |
US20070042406A1 (en) * | 2005-07-18 | 2007-02-22 | U.S. Genomics, Inc. | Diffusion mediated clean-up of a target carrier fluid |
JP5184353B2 (ja) * | 2005-07-20 | 2013-04-17 | コーニング インコーポレイテッド | ラベルフリーハイスループット生体分子スクリーニングシステム及び方法 |
WO2007024485A2 (en) * | 2005-08-11 | 2007-03-01 | Eksigent Technologies, Llc | Microfluidic reduction of diffusion and complience effect in a fluid mixing region |
DOP2006000277A (es) | 2005-12-12 | 2007-08-31 | Bayer Pharmaceuticals Corp | Anticuerpos anti mn y métodos para su utilización |
US7749365B2 (en) | 2006-02-01 | 2010-07-06 | IntegenX, Inc. | Optimized sample injection structures in microfluidic separations |
EP1979079A4 (de) | 2006-02-03 | 2012-11-28 | Integenx Inc | Mikrofluidische vorrichtungen |
US7766033B2 (en) | 2006-03-22 | 2010-08-03 | The Regents Of The University Of California | Multiplexed latching valves for microfluidic devices and processors |
US11287421B2 (en) | 2006-03-24 | 2022-03-29 | Labrador Diagnostics Llc | Systems and methods of sample processing and fluid control in a fluidic system |
US8741230B2 (en) * | 2006-03-24 | 2014-06-03 | Theranos, Inc. | Systems and methods of sample processing and fluid control in a fluidic system |
EP2012923A1 (de) * | 2006-04-07 | 2009-01-14 | Corning Incorporated | Geschlossene durchflussmikroplatte sowie verfahren zu ihrer verwendung und herstellung |
US8974748B2 (en) * | 2007-04-05 | 2015-03-10 | Corning Incorporated | Dual inlet microchannel device and method for using same |
US8007999B2 (en) | 2006-05-10 | 2011-08-30 | Theranos, Inc. | Real-time detection of influenza virus |
CN101534917A (zh) | 2006-05-22 | 2009-09-16 | 纽约市哥伦比亚大学理事会 | 采用萃取流体排出流过滤的微流无膜交换系统和方法 |
WO2008005292A1 (en) * | 2006-06-30 | 2008-01-10 | Corning Incorporated | Fluid handling system for flow-through assay |
US8263415B2 (en) * | 2006-09-14 | 2012-09-11 | Ge Healthcare Bio-Sciences Ab | Method of determining analyte concentration |
US7976217B2 (en) * | 2006-09-15 | 2011-07-12 | Corning Incorporated | Screening system and method for analyzing a plurality of biosensors |
WO2008052138A2 (en) | 2006-10-25 | 2008-05-02 | The Regents Of The University Of California | Inline-injection microdevice and microfabricated integrated dna analysis system using same |
US20080113391A1 (en) | 2006-11-14 | 2008-05-15 | Ian Gibbons | Detection and quantification of analytes in bodily fluids |
WO2008085991A2 (en) | 2007-01-08 | 2008-07-17 | U.S. Genomics, Inc. | Reaction chamber |
US20110039303A1 (en) | 2007-02-05 | 2011-02-17 | Stevan Bogdan Jovanovich | Microfluidic and nanofluidic devices, systems, and applications |
JP4767196B2 (ja) * | 2007-02-21 | 2011-09-07 | シャープ株式会社 | 流路反応方法および流路反応装置 |
US7867783B2 (en) | 2007-02-22 | 2011-01-11 | Maven Technologies, Llc | Apparatus and method for performing ligand binding assays on microarrays in multiwell plates |
DE102007012866A1 (de) | 2007-03-09 | 2008-09-18 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Flusskanalsystem und Verfahren zum Anbinden von Analyten an Liganden |
US7863037B1 (en) | 2007-04-04 | 2011-01-04 | Maven Technologies, Llc | Ligand binding assays on microarrays in closed multiwell plates |
US20090041633A1 (en) * | 2007-05-14 | 2009-02-12 | Dultz Shane C | Apparatus and method for performing ligand binding assays on microarrays in multiwell plates |
US7799558B1 (en) | 2007-05-22 | 2010-09-21 | Dultz Shane C | Ligand binding assays on microarrays in closed multiwell plates |
US8298496B2 (en) * | 2007-07-23 | 2012-10-30 | Flir Systems, Inc. | Fluidic configuration for flow injection analysis |
US8454906B2 (en) | 2007-07-24 | 2013-06-04 | The Regents Of The University Of California | Microfabricated droplet generator for single molecule/cell genetic analysis in engineered monodispersed emulsions |
US8158430B1 (en) | 2007-08-06 | 2012-04-17 | Theranos, Inc. | Systems and methods of fluidic sample processing |
DE102007038777A1 (de) * | 2007-08-10 | 2009-02-19 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Zellkulturmesssystem und Verfahren für vergleichende Untersuchungen an Zellkulturen |
US8354280B2 (en) * | 2007-09-06 | 2013-01-15 | Bioscale, Inc. | Reusable detection surfaces and methods of using same |
EP2238165B1 (de) | 2008-01-07 | 2017-07-05 | Government of the United States of America, as represented by the Secretary, Department of Health and Human Services | Anti-hiv-domäne-antikörper sowie verfahren zu ihrer herstellung und verwendung |
KR20110030415A (ko) | 2008-01-22 | 2011-03-23 | 인터젠엑스 인크. | 만능 샘플 제조 시스템 및 집적 분석 시스템에서의 용도 |
US8397762B2 (en) * | 2008-02-04 | 2013-03-19 | Bioscale, Inc. | Fluidic system with improved flow characteristics |
MX2010008591A (es) | 2008-02-04 | 2010-08-30 | Univ Columbia | Dispositivos, sistemas y metodos de separacion de fluidos. |
GB0802084D0 (en) * | 2008-02-05 | 2008-03-12 | Univ Dublin City | Microfluidic device for assessing cell surface interactions |
US7981664B1 (en) | 2008-05-22 | 2011-07-19 | Maven Technologies, Llc | Apparatus and method for performing ligand binding assays on microarrays in multiwell plates |
US8039270B2 (en) * | 2008-05-22 | 2011-10-18 | Maven Technologies, Llc | Apparatus and method for performing ligand binding assays on microarrays in multiwell plates |
US8361716B2 (en) | 2008-10-03 | 2013-01-29 | Pathogenetix, Inc. | Focusing chamber |
CN102341691A (zh) | 2008-12-31 | 2012-02-01 | 尹特根埃克斯有限公司 | 具有微流体芯片的仪器 |
WO2010141326A1 (en) | 2009-06-02 | 2010-12-09 | Integenx Inc. | Fluidic devices with diaphragm valves |
RU2559541C2 (ru) | 2009-06-05 | 2015-08-10 | Интедженкс Инк. | Универсальная система подготовки образцов и применение в интегрированной системе анализа |
NZ599873A (en) | 2009-10-19 | 2014-09-26 | Theranos Inc | Integrated health data capture and analysis system |
US8584703B2 (en) | 2009-12-01 | 2013-11-19 | Integenx Inc. | Device with diaphragm valve |
US8355133B2 (en) * | 2009-12-30 | 2013-01-15 | Maven Technologies, Llc | Biological testing with sawtooth-shaped prisms |
EP2524230A4 (de) * | 2010-01-13 | 2013-07-24 | Nomadics Inc | In-situ-verdünnungsverfahren und system zur messung molekularer und chemischer interaktionen |
US8512538B2 (en) | 2010-05-28 | 2013-08-20 | Integenx Inc. | Capillary electrophoresis device |
US8748191B2 (en) * | 2010-08-02 | 2014-06-10 | Ecolab Usa Inc. | Stop-flow analytical systems and methods |
EP2606154B1 (de) | 2010-08-20 | 2019-09-25 | Integenx Inc. | Integriertes analysesystem |
US8763642B2 (en) | 2010-08-20 | 2014-07-01 | Integenx Inc. | Microfluidic devices with mechanically-sealed diaphragm valves |
US9387476B2 (en) | 2010-10-27 | 2016-07-12 | Illumina, Inc. | Flow cells for biological or chemical analysis |
US20130295587A1 (en) * | 2011-01-24 | 2013-11-07 | Ge Healthcare Bio-Sciences Ab | Method of coupling binding agents to a substrate surface |
JP5283729B2 (ja) * | 2011-04-28 | 2013-09-04 | シャープ株式会社 | 流路反応方法および流路反応装置 |
JP6145096B2 (ja) | 2011-09-28 | 2017-06-07 | ジーイー・ヘルスケア・バイオサイエンス・アクチボラグ | 表面プラズモン共鳴バイオセンサシステム |
US9958438B2 (en) | 2011-09-30 | 2018-05-01 | Ge Healthcare Bio-Sciences Ab | Multi-channel flowcell |
US20150136604A1 (en) | 2011-10-21 | 2015-05-21 | Integenx Inc. | Sample preparation, processing and analysis systems |
US10865440B2 (en) | 2011-10-21 | 2020-12-15 | IntegenX, Inc. | Sample preparation, processing and analysis systems |
US8795605B2 (en) | 2012-01-12 | 2014-08-05 | Fred C. Senftleber | Apparatus and methods for transferring materials between locations possessing different cross-sectional areas with minimal band spreading and dispersion due to unequal path-lengths |
US9632026B2 (en) | 2012-01-23 | 2017-04-25 | Flir Systems, Inc. | Optical biosensor referencing method |
US8685708B2 (en) | 2012-04-18 | 2014-04-01 | Pathogenetix, Inc. | Device for preparing a sample |
US9028776B2 (en) | 2012-04-18 | 2015-05-12 | Toxic Report Llc | Device for stretching a polymer in a fluid sample |
EP2859325A2 (de) | 2012-06-10 | 2015-04-15 | Bio-Rad Laboratories, Inc. | Optisches detektionssystem für flüssigkeitsproben |
WO2014003689A1 (en) * | 2012-06-28 | 2014-01-03 | Nanyang Technological University | Detection device and method for detection of particles |
KR20140021899A (ko) * | 2012-08-13 | 2014-02-21 | 삼성전자주식회사 | 컨텐츠를 이동시키기 위한 방법 및 그 전자 장치 |
US9990464B1 (en) | 2012-10-09 | 2018-06-05 | Pall Corporation | Label-free biomolecular interaction analysis using a rapid analyte dispersion injection method |
CN102886236B (zh) * | 2012-10-31 | 2014-06-04 | 厦门大学 | 一种纳米尺度的微通道内流体的驱动方法 |
CN103308426B (zh) * | 2013-05-20 | 2015-12-09 | 中南大学 | 液体分子扩散系数的微流控测试方法 |
US10191071B2 (en) | 2013-11-18 | 2019-01-29 | IntegenX, Inc. | Cartridges and instruments for sample analysis |
US9377400B2 (en) | 2014-03-31 | 2016-06-28 | Redshift Systems Corporation | Motion modulation fluidic analyzer system |
EP3123148B1 (de) | 2014-03-31 | 2020-05-27 | Redshift Systems Corporation | Flüssigkeitsanalysegerät mit modulation für flüssigkeiten und gase |
US10208332B2 (en) | 2014-05-21 | 2019-02-19 | Integenx Inc. | Fluidic cartridge with valve mechanism |
EP3209410A4 (de) | 2014-10-22 | 2018-05-02 | IntegenX Inc. | Systeme und verfahren zur automatisierten vorbereitung, verarbeitung und analyse von proben |
WO2017045703A1 (en) * | 2015-09-15 | 2017-03-23 | Siemens Healthcare Gmbh | A technique for focusing a sample in a flow |
US10334967B2 (en) | 2016-07-25 | 2019-07-02 | Retail Space Solutions Llc | Merchandiser and methods relating to same |
EP3857199A4 (de) * | 2018-09-28 | 2022-09-07 | Nicoya Lifesciences, Inc. | Plasmonenresonanzsystem, instrument und vorrichtung zur messung von molekularen wechselwirkungen |
DE102020107645A1 (de) * | 2020-03-19 | 2021-09-23 | Bruker Daltonics GmbH & Co. KG | Betrieb einer Mikrofluidik-Vorrichtung bei der Analyse von Probesubstanzen |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK150802C (da) * | 1974-09-16 | 1988-02-01 | Bifok Ab | Fremgangsmaade og apparat til kontinuerlig hoejhastighedsanalyse af en vaeskeproeve i en baererstroem |
DE2521236C3 (de) * | 1975-05-10 | 1978-12-14 | Hildegard Dr. 4400 Muenster Goehde Geb. Kuhl | Einrichtung zum Zählen und Messen von in einer Flüssigkeit suspendierten Teilchen |
NL8700851A (nl) | 1987-04-10 | 1988-11-01 | Tno | Werkwijze en inrichting voor het detecteren van zeer lage concentraties van een in een meetmedium aanwezige chemische component onder toepassing van oppervlakte-plasmonresonantie en elektrochemisch gestimuleerde adsorptie. |
CA1321488C (en) | 1987-08-22 | 1993-08-24 | Martin Francis Finlan | Biological sensors |
SE8804074D0 (sv) * | 1988-11-10 | 1988-11-10 | Pharmacia Ab | Sensorenhet och dess anvaendning i biosensorsystem |
SE462408B (sv) | 1988-11-10 | 1990-06-18 | Pharmacia Ab | Optiskt biosensorsystem utnyttjande ytplasmonresonans foer detektering av en specific biomolekyl, saett att kalibrera sensoranordningen samt saett att korrigera foer baslinjedrift i systemet |
DE4024476C1 (de) | 1990-08-02 | 1992-02-27 | Boehringer Mannheim Gmbh, 6800 Mannheim, De | |
US5458852A (en) | 1992-05-21 | 1995-10-17 | Biosite Diagnostics, Inc. | Diagnostic devices for the controlled movement of reagents without membranes |
DE69429262T2 (de) | 1993-05-18 | 2002-07-25 | Univ Utah Res Found | Vorrichtung und verfahren fuer homogene multianalyt-immuno-assays |
DE4411268C2 (de) * | 1994-03-31 | 2001-02-01 | Danfoss As | Analyseverfahren und Analysevorrichtung |
US5485277A (en) * | 1994-07-26 | 1996-01-16 | Physical Optics Corporation | Surface plasmon resonance sensor and methods for the utilization thereof |
SE9403245D0 (sv) | 1994-09-26 | 1994-09-26 | Pharmacia Biosensor Ab | Improvements relating to bilayer lipid membranes |
EP1890130A3 (de) | 1995-05-12 | 2008-02-27 | Novartis AG | Sensorenplattform zur parallelen Erkennung mehrerer Analyte mittels sehr schwach leuchtender Lumineszenzen |
US5716852A (en) * | 1996-03-29 | 1998-02-10 | University Of Washington | Microfabricated diffusion-based chemical sensor |
AU6354796A (en) | 1995-06-23 | 1997-01-22 | Novartis Ag | Flow cell |
US6200814B1 (en) | 1998-01-20 | 2001-03-13 | Biacore Ab | Method and device for laminar flow on a sensing surface |
-
1998
- 1998-01-20 US US09/009,139 patent/US6200814B1/en not_active Expired - Lifetime
-
1999
- 1999-01-19 JP JP2000540427A patent/JP4340766B2/ja not_active Expired - Lifetime
- 1999-01-19 EP EP99903988A patent/EP1021703B1/de not_active Expired - Lifetime
- 1999-01-19 WO PCT/SE1999/000063 patent/WO1999036766A1/en active IP Right Grant
- 1999-01-19 DE DE69900714T patent/DE69900714T2/de not_active Expired - Lifetime
-
2001
- 2001-01-12 US US09/760,213 patent/US7105356B2/en not_active Expired - Fee Related
-
2005
- 2005-12-06 US US11/295,161 patent/US7582487B2/en not_active Expired - Fee Related
-
2009
- 2009-06-30 US US12/494,911 patent/US7811515B2/en not_active Expired - Fee Related
- 2009-06-30 US US12/494,930 patent/US7736587B2/en not_active Expired - Fee Related
-
2010
- 2010-04-26 US US12/767,221 patent/US8021626B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
US20090263285A1 (en) | 2009-10-22 |
US7582487B2 (en) | 2009-09-01 |
JP2002509248A (ja) | 2002-03-26 |
US20100260642A1 (en) | 2010-10-14 |
US20060134800A1 (en) | 2006-06-22 |
US6200814B1 (en) | 2001-03-13 |
EP1021703A1 (de) | 2000-07-26 |
US20090263284A1 (en) | 2009-10-22 |
WO1999036766A1 (en) | 1999-07-22 |
US8021626B2 (en) | 2011-09-20 |
EP1021703B1 (de) | 2001-11-21 |
JP4340766B2 (ja) | 2009-10-07 |
US20010055817A1 (en) | 2001-12-27 |
US7736587B2 (en) | 2010-06-15 |
US7811515B2 (en) | 2010-10-12 |
DE69900714D1 (de) | 2002-02-21 |
US7105356B2 (en) | 2006-09-12 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DE69900714D1 (de) | Verfahren und vorrichtung zur laminaren strömung an einer sensoroberfläche | |
DE59913456D1 (de) | Verfahren und vorrichtung zur stabilisierung eines fahrzeuges | |
DE69937839D1 (de) | Vorrichtung und verfahren zur lokalisierung einer kodiereinheit | |
DE59912621D1 (de) | Vorrichtung und verfahren zur stabilisierung eines fahrzeuges | |
DE69632615D1 (de) | Verfahren und Vorrichtung zur Detektion einer Oberflächenlage und Verfahren und Vorrichtung zur Abtastbelichtung | |
DE59910320D1 (de) | Verfahren und Vorrichtung zur Messung einer Zustandsgrösse | |
DE878824T1 (de) | Verfahren und Gerät zur Ätzung eines Werkstücks | |
DE69736196D1 (de) | Verfahren und vorrichtung zur wegleitung einer kurznachricht | |
DE50015979D1 (de) | Verfahren und vorrichtung zur ermittlung einer geschwindigkeitsgrösse | |
DE69526779D1 (de) | Vorrichtung und Verfahren zur Detektion einer angezeigten Position | |
DE69907878D1 (de) | Verfahren und vorrichtung zur elektrokoagulation von flüssigkeiten | |
DE60015774D1 (de) | Verfahren und vorrichtung zur reinigung eines bohrloches | |
DE69912685D1 (de) | Vorrichtung und Verfahren zur Normalisierung und Eichung einer Sensormatrix | |
DE59900196D1 (de) | Verfahren und Vorrichtung zur Funktionsüberwachung eines Sensorbausteins | |
DE59902679D1 (de) | Verfahren und vorrichtung zur de-sulfatierung einer katalysatoreinrichtung | |
DE69924697D1 (de) | Vorrichtung und Verfahren zur Verbindung einer leitfähigen Sensorschicht | |
DE60120927D1 (de) | Verfahren und vorrichtung zum anbringen von sensoren an einer sitzeinheit | |
DE59811538D1 (de) | Verfahren und Vorrichtung zur Abtragung einer Oberflächenschicht | |
DE69724138D1 (de) | Gerät und dazugehöriges verfahren zur kalibrierung einer vorrichtung | |
DE69904764T2 (de) | Verfahren und Vorrichtung zur Mustererkennung | |
DE69926137D1 (de) | Verfahren und vorrichtung zur befestigung eines bauelementes | |
DE69733087D1 (de) | Verfahren und vorrichtung zur scharfeinstellung einer halbleiterscheibe | |
DE69903937T2 (de) | Vorrichtung und verfahren zur reduzierung der einschaltzeit eines kristalloszillators | |
DE59808255D1 (de) | Verfahren und vorrichtung zur ermittlung einer die fahrzeuggeschwindigkeit beschreibenden grösse | |
DE69919420D1 (de) | Verfahren und Vorrichtung zur Mustererkennung |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8327 | Change in the person/name/address of the patent owner |
Owner name: GE HEALTHCARE BIO-SCIENCES AB, UPPSALA, SE |
|
8328 | Change in the person/name/address of the agent |
Representative=s name: HAMMONDS LLP, LONDON, GB |
|
R082 | Change of representative |
Ref document number: 1021703 Country of ref document: EP Representative=s name: J D REYNOLDS & CO., GB |