DE69737325D1 - Vernetzung von polyethylen zur verringerung der abnutzung unter anwendung von strahlung und thermischer behandlung - Google Patents

Vernetzung von polyethylen zur verringerung der abnutzung unter anwendung von strahlung und thermischer behandlung

Info

Publication number
DE69737325D1
DE69737325D1 DE69737325T DE69737325T DE69737325D1 DE 69737325 D1 DE69737325 D1 DE 69737325D1 DE 69737325 T DE69737325 T DE 69737325T DE 69737325 T DE69737325 T DE 69737325T DE 69737325 D1 DE69737325 D1 DE 69737325D1
Authority
DE
Germany
Prior art keywords
networking
radiation
polyethylene
thermal treatment
reduce wear
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69737325T
Other languages
English (en)
Other versions
DE69737325T2 (de
Inventor
Fu-Wen Shen
A Mckellop
Ronald Salovey
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Orthopaedic Hospital
University of Southern California USC
Original Assignee
Orthopaedic Hospital
University of Southern California USC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27360900&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69737325(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Orthopaedic Hospital, University of Southern California USC filed Critical Orthopaedic Hospital
Application granted granted Critical
Publication of DE69737325D1 publication Critical patent/DE69737325D1/de
Publication of DE69737325T2 publication Critical patent/DE69737325T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/30767—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/46—Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor
    • A61F2/468—Testing instruments for artificial joints
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/16—Macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C71/00—After-treatment of articles without altering their shape; Apparatus therefor
    • B29C71/02—Thermal after-treatment
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C71/00—After-treatment of articles without altering their shape; Apparatus therefor
    • B29C71/04—After-treatment of articles without altering their shape; Apparatus therefor by wave energy or particle radiation, e.g. for curing or vulcanising preformed articles
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J3/00—Processes of treating or compounding macromolecular substances
    • C08J3/28—Treatment by wave energy or particle radiation
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J7/00—Chemical treatment or coating of shaped articles made of macromolecular substances
    • C08J7/08—Heat treatment
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J7/00—Chemical treatment or coating of shaped articles made of macromolecular substances
    • C08J7/12—Chemical modification
    • C08J7/123—Treatment by wave energy or particle radiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/3094—Designing or manufacturing processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/32—Joints for the hip
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/32—Joints for the hip
    • A61F2/34—Acetabular cups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30003—Material related properties of the prosthesis or of a coating on the prosthesis
    • A61F2002/3006—Properties of materials and coating materials
    • A61F2002/30084—Materials having a crystalline structure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/32—Joints for the hip
    • A61F2/34—Acetabular cups
    • A61F2002/3412—Acetabular cups with pins or protrusions, e.g. non-sharp pins or protrusions projecting from a shell surface
    • A61F2002/3414—Polar protrusion, e.g. for centering two concentric shells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/32—Joints for the hip
    • A61F2/34—Acetabular cups
    • A61F2002/3429—Acetabular cups with an integral peripheral collar or flange, e.g. oriented away from the shell centre line
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/32—Joints for the hip
    • A61F2/36—Femoral heads ; Femoral endoprostheses
    • A61F2/3609—Femoral heads or necks; Connections of endoprosthetic heads or necks to endoprosthetic femoral shafts
    • A61F2002/3611—Heads or epiphyseal parts of femur
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C35/00—Heating, cooling or curing, e.g. crosslinking or vulcanising; Apparatus therefor
    • B29C35/02—Heating or curing, e.g. crosslinking or vulcanizing during moulding, e.g. in a mould
    • B29C35/08—Heating or curing, e.g. crosslinking or vulcanizing during moulding, e.g. in a mould by wave energy or particle radiation
    • B29C35/0805—Heating or curing, e.g. crosslinking or vulcanizing during moulding, e.g. in a mould by wave energy or particle radiation using electromagnetic radiation
    • B29C2035/085—Heating or curing, e.g. crosslinking or vulcanizing during moulding, e.g. in a mould by wave energy or particle radiation using electromagnetic radiation using gamma-ray
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C71/00—After-treatment of articles without altering their shape; Apparatus therefor
    • B29C71/02—Thermal after-treatment
    • B29C2071/022—Annealing
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C43/00—Compression moulding, i.e. applying external pressure to flow the moulding material; Apparatus therefor
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C43/00—Compression moulding, i.e. applying external pressure to flow the moulding material; Apparatus therefor
    • B29C43/02—Compression moulding, i.e. applying external pressure to flow the moulding material; Apparatus therefor of articles of definite length, i.e. discrete articles
    • B29C43/16—Forging
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29K—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES B29B, B29C OR B29D, RELATING TO MOULDING MATERIALS OR TO MATERIALS FOR MOULDS, REINFORCEMENTS, FILLERS OR PREFORMED PARTS, e.g. INSERTS
    • B29K2023/00—Use of polyalkenes or derivatives thereof as moulding material
    • B29K2023/04—Polymers of ethylene
    • B29K2023/06—PE, i.e. polyethylene
    • B29K2023/0658—PE, i.e. polyethylene characterised by its molecular weight
    • B29K2023/0675—HMWPE, i.e. high molecular weight polyethylene
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29K—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES B29B, B29C OR B29D, RELATING TO MOULDING MATERIALS OR TO MATERIALS FOR MOULDS, REINFORCEMENTS, FILLERS OR PREFORMED PARTS, e.g. INSERTS
    • B29K2023/00—Use of polyalkenes or derivatives thereof as moulding material
    • B29K2023/04—Polymers of ethylene
    • B29K2023/06—PE, i.e. polyethylene
    • B29K2023/0658—PE, i.e. polyethylene characterised by its molecular weight
    • B29K2023/0683—UHMWPE, i.e. ultra high molecular weight polyethylene
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29K—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES B29B, B29C OR B29D, RELATING TO MOULDING MATERIALS OR TO MATERIALS FOR MOULDS, REINFORCEMENTS, FILLERS OR PREFORMED PARTS, e.g. INSERTS
    • B29K2995/00—Properties of moulding materials, reinforcements, fillers, preformed parts or moulds
    • B29K2995/0037—Other properties
    • B29K2995/0087—Wear resistance
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29K—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES B29B, B29C OR B29D, RELATING TO MOULDING MATERIALS OR TO MATERIALS FOR MOULDS, REINFORCEMENTS, FILLERS OR PREFORMED PARTS, e.g. INSERTS
    • B29K2995/00—Properties of moulding materials, reinforcements, fillers, preformed parts or moulds
    • B29K2995/0037—Other properties
    • B29K2995/0089—Impact strength or toughness
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29L—INDEXING SCHEME ASSOCIATED WITH SUBCLASS B29C, RELATING TO PARTICULAR ARTICLES
    • B29L2031/00—Other particular articles
    • B29L2031/753—Medical equipment; Accessories therefor
    • B29L2031/7532—Artificial members, protheses
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J2323/00—Characterised by the use of homopolymers or copolymers of unsaturated aliphatic hydrocarbons having only one carbon-to-carbon double bond; Derivatives of such polymers
    • C08J2323/02—Characterised by the use of homopolymers or copolymers of unsaturated aliphatic hydrocarbons having only one carbon-to-carbon double bond; Derivatives of such polymers not modified by chemical after treatment
    • C08J2323/04—Homopolymers or copolymers of ethene
    • C08J2323/06—Polyethene
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S525/00—Synthetic resins or natural rubbers -- part of the class 520 series
    • Y10S525/937—Utility as body contact e.g. implant, contact lens or I.U.D.
DE69737325T 1996-07-09 1997-07-08 Vernetzung von polyethylen zur verringerung der abnutzung unter anwendung von strahlung und thermischer behandlung Expired - Lifetime DE69737325T2 (de)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US1785296P 1996-07-09 1996-07-09
US17852P 1996-07-09
US2571296P 1996-09-10 1996-09-10
US25712P 1996-09-10
US4439097P 1997-04-29 1997-04-29
US44390 1997-04-29
PCT/US1997/011947 WO1998001085A1 (en) 1996-07-09 1997-07-08 Crosslinking of polyethylene for low wear using radiation and thermal treatments

Publications (2)

Publication Number Publication Date
DE69737325D1 true DE69737325D1 (de) 2007-03-22
DE69737325T2 DE69737325T2 (de) 2007-11-22

Family

ID=27360900

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69737325T Expired - Lifetime DE69737325T2 (de) 1996-07-09 1997-07-08 Vernetzung von polyethylen zur verringerung der abnutzung unter anwendung von strahlung und thermischer behandlung

Country Status (7)

Country Link
US (6) US6800670B2 (de)
EP (3) EP1795212A3 (de)
JP (2) JP2000514481A (de)
AU (1) AU3655197A (de)
CA (1) CA2260241C (de)
DE (1) DE69737325T2 (de)
WO (1) WO1998001085A1 (de)

Families Citing this family (124)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0729981B1 (de) 1994-09-21 2002-03-20 Bmg Incorporated Polyethylenguss mit ultrahohem molekulargewicht für künstliche verbindungen und verfahren zu dessen herstellung
CA2166450C (en) * 1995-01-20 2008-03-25 Ronald Salovey Chemically crosslinked ultrahigh molecular weight polyethylene for artificial human joints
US20050125074A1 (en) * 1995-01-20 2005-06-09 Ronald Salovey Crosslinking of polyethylene for low wear using radiation and thermal treatments
US5879400A (en) 1996-02-13 1999-03-09 Massachusetts Institute Of Technology Melt-irradiated ultra high molecular weight polyethylene prosthetic devices
US8865788B2 (en) 1996-02-13 2014-10-21 The General Hospital Corporation Radiation and melt treated ultra high molecular weight polyethylene prosthetic devices
DE69737325T2 (de) 1996-07-09 2007-11-22 University Of Southern California, Los Angeles Vernetzung von polyethylen zur verringerung der abnutzung unter anwendung von strahlung und thermischer behandlung
US6017975A (en) 1996-10-02 2000-01-25 Saum; Kenneth Ashley Process for medical implant of cross-linked ultrahigh molecular weight polyethylene having improved balance of wear properties and oxidation resistance
AU4986497A (en) * 1996-10-15 1998-05-11 Orthopaedic Hospital, The Wear resistant surface-gradient cross-linked polyethylene
US7959652B2 (en) 2005-04-18 2011-06-14 Kyphon Sarl Interspinous process implant having deployable wings and method of implantation
US6068630A (en) 1997-01-02 2000-05-30 St. Francis Medical Technologies, Inc. Spine distraction implant
US7306628B2 (en) 2002-10-29 2007-12-11 St. Francis Medical Technologies Interspinous process apparatus and method with a selectably expandable spacer
EP0963824B1 (de) * 1998-06-10 2004-12-08 DePuy Products, Inc. Verfahren zur Herstellung vernetzter, geformter Kunststofflager
US6692679B1 (en) 1998-06-10 2004-02-17 Depuy Orthopaedics, Inc. Cross-linked molded plastic bearings
FR2784290B1 (fr) * 1998-10-07 2001-02-09 Pierre Kehr Procede de fabrication d'un implant cotyloidien de prothese de hanche
US6245276B1 (en) 1999-06-08 2001-06-12 Depuy Orthopaedics, Inc. Method for molding a cross-linked preform
US6627141B2 (en) 1999-06-08 2003-09-30 Depuy Orthopaedics, Inc. Method for molding a cross-linked preform
US6432349B1 (en) 1999-06-29 2002-08-13 Zimmer, Inc. Process of making an articulating bearing surface
EP1072277A1 (de) * 1999-07-29 2001-01-31 Depuy Orthopaedics, Inc. Hitzebehandlung von gamma-bestrahlten Implantaten zur Erhöhung der mechanischen Stabilität
US6143232A (en) * 1999-07-29 2000-11-07 Bristol-Meyers Squibb Company Method of manufacturing an articulating bearing surface for an orthopaedic implant
US6184265B1 (en) 1999-07-29 2001-02-06 Depuy Orthopaedics, Inc. Low temperature pressure stabilization of implant component
EP1072274A1 (de) * 1999-07-29 2001-01-31 Depuy Orthopaedics, Inc. Zweistufige Gammabestrahlung von Polymer-Bioimplantaten
US6365089B1 (en) 1999-09-24 2002-04-02 Zimmer, Inc. Method for crosslinking UHMWPE in an orthopaedic implant
SK8232002A3 (en) * 1999-12-17 2003-05-02 Cartificial As Medico Chemical A prosthetic device
US6395799B1 (en) 2000-02-21 2002-05-28 Smith & Nephew, Inc. Electromagnetic and mechanical wave energy treatments of UHMWPE
EP2275052A1 (de) 2000-04-27 2011-01-19 Orthopaedic Hospital Oxidationsbeständige und abnutzungsbeständige Polyethylene für den Ersatz menschlicher Gelenke und Herstellungsverfahren dafür
ES2286131T3 (es) 2000-07-31 2007-12-01 Massachusetts General Hospital Componente acetabular monopolar constreñido.
US6818172B2 (en) 2000-09-29 2004-11-16 Depuy Products, Inc. Oriented, cross-linked UHMWPE molding for orthopaedic applications
AU2002218000A1 (en) * 2000-11-01 2002-05-15 Genomic Solutions, Inc. Compositions and systems for identifying and comparing expressed genes (mrnas) in eukaryotic organisms
DE10105085C1 (de) 2001-02-05 2002-04-18 Plus Endoprothetik Ag Rotkreuz Verfahren zur Herstellung von Implantatteilen aus hochvernetztem UHMWPE und deren Verwendung
US6547828B2 (en) 2001-02-23 2003-04-15 Smith & Nephew, Inc. Cross-linked ultra-high molecular weight polyethylene for medical implant use
US9155626B2 (en) 2012-09-10 2015-10-13 Acumed Llc Radial head prosthesis with floating articular member
US6652586B2 (en) * 2001-07-18 2003-11-25 Smith & Nephew, Inc. Prosthetic devices employing oxidized zirconium and other abrasion resistant surfaces contacting surfaces of cross-linked polyethylene
US7182784B2 (en) 2001-07-18 2007-02-27 Smith & Nephew, Inc. Prosthetic devices employing oxidized zirconium and other abrasion resistant surfaces contacting surfaces of cross-linked polyethylene
GB0122117D0 (en) 2001-09-13 2001-10-31 United Ind Operations Ltd Method of crosslinking polyolefins
EP1308255A1 (de) * 2001-10-30 2003-05-07 Dsm N.V. Verfahren zum Herstellen eines geformten Teils aus Polyethylen mit ultrahochmolekularem Gewicht und durch dieses Verfahren hergestellte Faser
JP2005511216A (ja) * 2001-12-12 2005-04-28 デピュイ・プロダクツ・インコーポレイテッド 整形外科装置およびその作製方法
WO2003059200A1 (en) 2002-01-04 2003-07-24 Massachusetts General Hospital A high modulus crosslinked polyethylene with reduced residual free radical concentration prepared below the melt
US7819925B2 (en) * 2002-01-28 2010-10-26 Depuy Products, Inc. Composite prosthetic bearing having a crosslinked articulating surface and method for making the same
WO2003064141A1 (en) 2002-01-29 2003-08-07 Paul Smith Sintering ultrahigh molecular weight polyethylene
CA2429930C (en) * 2002-06-06 2008-10-14 Howmedica Osteonics Corp. Sequentially cross-linked polyethylene
US20040048958A1 (en) * 2002-09-06 2004-03-11 Didier David A. High temperature ultra high molecular weight polyethylene
JP2006511255A (ja) * 2002-10-11 2006-04-06 カーティフィシャル・アクティーゼルスカブ 層状構造を持つ生体適合性ポリマー製品を含む医療機器
WO2004037119A2 (en) 2002-10-23 2004-05-06 Mako Surgical Corp. Modular femoral component for a total knee joint replacement for minimally invasive implantation
US8070778B2 (en) 2003-05-22 2011-12-06 Kyphon Sarl Interspinous process implant with slide-in distraction piece and method of implantation
US7833246B2 (en) 2002-10-29 2010-11-16 Kyphon SÀRL Interspinous process and sacrum implant and method
US8048117B2 (en) 2003-05-22 2011-11-01 Kyphon Sarl Interspinous process implant and method of implantation
US7549999B2 (en) 2003-05-22 2009-06-23 Kyphon Sarl Interspinous process distraction implant and method of implantation
US7909853B2 (en) 2004-09-23 2011-03-22 Kyphon Sarl Interspinous process implant including a binder and method of implantation
US7749252B2 (en) 2005-03-21 2010-07-06 Kyphon Sarl Interspinous process implant having deployable wing and method of implantation
EP1596755B1 (de) * 2003-01-16 2016-10-12 Massachusetts General Hospital Verfahren zur herstellung von oxidationsbeständigem polymermaterial
US7241455B2 (en) * 2003-04-08 2007-07-10 Boston Scientific Scimed, Inc. Implantable or insertable medical devices containing radiation-crosslinked polymer for controlled delivery of a therapeutic agent
US7938861B2 (en) 2003-04-15 2011-05-10 Depuy Products, Inc. Implantable orthopaedic device and method for making the same
US20040254545A1 (en) * 2003-06-16 2004-12-16 Rider Dean Loller Method and apparatus for extending feeding tube longevity
WO2005048872A2 (en) 2003-06-27 2005-06-02 Advanced Bio Surfaces, Inc. System and method for ankle arthroplasty
JP2005237629A (ja) * 2004-02-26 2005-09-08 Kyocera Corp 人工関節およびその製造方法
ES2622873T3 (es) * 2004-03-11 2017-07-07 Acumed Llc Sistemas para el reemplazo óseo
EP1632254B1 (de) * 2004-07-27 2009-08-26 Cordis Corporation Verfahren zur Beschichtung von Stents
US8012209B2 (en) 2004-09-23 2011-09-06 Kyphon Sarl Interspinous process implant including a binder, binder aligner and method of implantation
US7344672B2 (en) 2004-10-07 2008-03-18 Biomet Manufacturing Corp. Solid state deformation processing of crosslinked high molecular weight polymeric materials
US7547405B2 (en) 2004-10-07 2009-06-16 Biomet Manufacturing Corp. Solid state deformation processing of crosslinked high molecular weight polymeric materials
US8262976B2 (en) 2004-10-07 2012-09-11 Biomet Manufacturing Corp. Solid state deformation processing of crosslinked high molecular weight polymeric materials
US7462318B2 (en) 2004-10-07 2008-12-09 Biomet Manufacturing Corp. Crosslinked polymeric material with enhanced strength and process for manufacturing
DE102004056713B4 (de) * 2004-11-24 2008-04-10 Mathys Ag Bettlach Verfahren zum Herstellen von Prothesenelementen sowie von Rohlingen von Prothesenelementen
US7763050B2 (en) 2004-12-13 2010-07-27 Warsaw Orthopedic, Inc. Inter-cervical facet implant with locking screw and method
US7591851B2 (en) 2004-12-13 2009-09-22 Kyphon Sarl Inter-cervical facet implant and method
US7335697B2 (en) 2004-12-23 2008-02-26 Depuy Products, Inc. Polymer composition comprising cross-linked polyethylene and methods for making the same
US7435372B2 (en) 2005-03-31 2008-10-14 Zimmer, Inc. Liquid bath annealing of polymers for orthopaedic implants
AU2006259555B2 (en) * 2005-06-14 2011-03-03 Omni Life Science, Inc. Crosslinked polyethylene article
US7538379B1 (en) * 2005-06-15 2009-05-26 Actel Corporation Non-volatile two-transistor programmable logic cell and array layout
US20060289098A1 (en) * 2005-06-23 2006-12-28 Balogh George F Tire containing cellular rubber within its tire cavity
ATE449618T1 (de) * 2005-08-18 2009-12-15 Zimmer Gmbh Ultrahochmolekulare polyethylen-artikel und verfahren zur herstellung von ultrahochmolekularen polyethylen-artikeln
ATE529464T1 (de) * 2005-08-22 2011-11-15 Gen Hospital Corp Dba Massachusetts General Hospital Oxidationsbeständiges homogenisiertes polymermaterial
US8343230B2 (en) * 2005-09-22 2013-01-01 Depuy Products, Inc. Orthopaedic bearing material
US20070077268A1 (en) * 2005-09-30 2007-04-05 Depuy Products, Inc. Hydrophobic carrier modified implants for beneficial agent delivery
US7635725B2 (en) * 2006-02-21 2009-12-22 The Brigham And Women's Hospital, Inc. Crosslinked polymers
US7812098B2 (en) * 2006-03-31 2010-10-12 Depuy Products, Inc. Bearing material of medical implant having reduced wear rate and method for reducing wear rate
ES2350708T3 (es) 2006-08-25 2011-01-26 Depuy Products, Inc. Material de soporte de implante médico.
AU2006350369A1 (en) * 2006-10-30 2008-05-08 Smith & Nephew Orthopaedics Ag Processes comprising crosslinking polyethylene or using crosslinked polyethylene
JP5448842B2 (ja) 2007-01-10 2014-03-19 バイオメト マニファクチャリング コーポレイション 膝関節プロテーゼシステムおよび埋込み方法
US8562616B2 (en) 2007-10-10 2013-10-22 Biomet Manufacturing, Llc Knee joint prosthesis system and method for implantation
US8163028B2 (en) 2007-01-10 2012-04-24 Biomet Manufacturing Corp. Knee joint prosthesis system and method for implantation
US8187280B2 (en) 2007-10-10 2012-05-29 Biomet Manufacturing Corp. Knee joint prosthesis system and method for implantation
US8328873B2 (en) 2007-01-10 2012-12-11 Biomet Manufacturing Corp. Knee joint prosthesis system and method for implantation
WO2008101134A1 (en) * 2007-02-14 2008-08-21 Brigham And Women's Hospital, Inc. Crosslinked polymers and methods of making the same
US20080319137A1 (en) 2007-04-10 2008-12-25 Zimmer, Inc. Antioxidant stabilized crosslinked ultra-high molecular weight polyethylene for medical device applications
US8664290B2 (en) 2007-04-10 2014-03-04 Zimmer, Inc. Antioxidant stabilized crosslinked ultra-high molecular weight polyethylene for medical device applications
US7947081B2 (en) * 2007-07-11 2011-05-24 Linares Medical Devices, Llc Skeletal implant for replacing a human bone
US8641959B2 (en) 2007-07-27 2014-02-04 Biomet Manufacturing, Llc Antioxidant doping of crosslinked polymers to form non-eluting bearing components
US7972380B2 (en) * 2007-09-17 2011-07-05 Linares Medical Devices, Llc Artificial joint support between first and second bones
GB0718821D0 (en) * 2007-09-26 2007-11-07 Benoist Girard Sas Cement spacer for use in prosthetic cup and method of use therein
ES2367155T3 (es) * 2007-11-06 2011-10-28 Dsm Ip Assets B.V. Procedimiento para producir polietileno de peso molecular (ultra)elevado.
ES2374596T3 (es) * 2007-11-06 2012-02-20 Dsm Ip Assets B.V. Proceso para producción de polietileno de peso molecular alto.
US9539097B2 (en) 2007-11-08 2017-01-10 Linares Medical Devices, Llc Hip and knee joint assemblies incorporating debris collection architecture between the ball and seat interface
US8979938B2 (en) * 2007-11-08 2015-03-17 Linares Medical Devices, Llc Artificial knee implant including liquid ballast supporting / rotating surfaces and incorporating flexible multi-material and natural lubricant retaining matrix applied to a joint surface
US8764837B2 (en) * 2008-03-26 2014-07-01 Linares Medical Devices, Llc Reinforced joint assembly
US8828088B2 (en) * 2007-11-08 2014-09-09 Linares Medical Devices, Llc Joint assembly incorporating undercut surface design to entrap accumulating wear debris from plastic joint assembly
US20100003828A1 (en) * 2007-11-28 2010-01-07 Guowen Ding Methods for adjusting critical dimension uniformity in an etch process with a highly concentrated unsaturated hydrocarbon gas
EP2249887B1 (de) 2008-01-30 2017-06-21 Zimmer, Inc. Orthopädischer bestandteil geringer steifheit
US8702801B2 (en) * 2008-02-25 2014-04-22 Linares Medical Devices, Llc Artificial wear resistant plug for mounting to existing joint bone
JP5311457B2 (ja) * 2008-06-20 2013-10-09 ナカシマメディカル株式会社 人工関節用摺動部材の成形方法及びこの方法によって成形された人工関節用摺動部材
DE102008047009B4 (de) * 2008-07-11 2020-08-06 Mathys Ag Bettlach Gelenkpfanne mit physiologischer Lastübertragung
KR20110053361A (ko) * 2008-08-20 2011-05-20 이 아이 듀폰 디 네모아 앤드 캄파니 고온 마모 수명의 평가 방법
JP5610394B2 (ja) * 2008-11-20 2014-10-22 国立大学法人 東京医科歯科大学 有床義歯及びその製造方法
WO2010057644A1 (en) * 2008-11-20 2010-05-27 Zimmer Gmbh Polyethylene materials
US7935740B2 (en) 2008-12-30 2011-05-03 Basell Poliolefine Italia S.R.L. Process for producing high melt strength polypropylene
KR101040567B1 (ko) 2009-08-11 2011-06-16 (주)오티스바이오텍 인공관절용 초고분자량 폴리에틸렌 라이너의 제조방법
GB0922339D0 (en) * 2009-12-21 2010-02-03 Mcminn Derek J W Acetabular cup prothesis and introducer thereof
US9132209B2 (en) 2010-05-07 2015-09-15 Howmedia Osteonics Corp. Surface crosslinked polyethylene
US8926705B2 (en) 2010-05-10 2015-01-06 Linares Medical Devices, Llc Implantable joint assembly featuring debris entrapment chamber subassemblies along with opposing magnetic fields generated between articulating implant components in order to minimize frictional force and associated wear
US8399535B2 (en) 2010-06-10 2013-03-19 Zimmer, Inc. Polymer [[s]] compositions including an antioxidant
EP2856978B8 (de) 2012-05-31 2017-12-13 KYOCERA Corporation Liner für implantate und verfahren zu seiner herstellung
US9586370B2 (en) 2013-08-15 2017-03-07 Biomet Manufacturing, Llc Method for making ultra high molecular weight polyethylene
EP3052562B1 (de) 2013-10-01 2017-11-08 Zimmer, Inc. Polymerzusammensetzungen, enthaltend ein oder mehrere geschützte antioxidantien
AU2015229947A1 (en) 2014-03-12 2016-10-27 Zimmer, Inc. Melt-stabilized ultra high molecular weight polyethylene and method of making the same
CA2969751C (en) 2014-12-03 2020-09-22 Zimmer, Inc. Antioxidant-infused ultra high molecular weight polyethylene
US9763792B2 (en) 2015-10-01 2017-09-19 Acumed Llc Radial head prosthesis with rotate-to-lock interface
US11739177B2 (en) 2018-04-20 2023-08-29 Adaptive 3D Technologies Sealed isocyanates
EP3781375A4 (de) * 2018-04-20 2021-09-29 Benjamin Lund Versiegelte isocyanate
US11911956B2 (en) 2018-11-21 2024-02-27 Adaptive 3D Technologies Using occluding fluids to augment additive manufacturing processes
AU2019391014A1 (en) 2018-12-03 2021-06-10 Forta, Llc Radiation-treated fibers, methods of treating and applications for use
DE102021103016A1 (de) * 2021-02-09 2022-08-11 Aesculap Ag Verfahren zur Herstellung eines Gleitflächenelements, Gleitflächenelement und Kniegelenkendoprothese
CN117881737A (zh) 2021-08-04 2024-04-12 罗姆化学有限责任公司 用于摩擦学应用的基于聚(甲基)丙烯酰亚胺的聚合物组合物
WO2023139195A1 (en) 2022-01-24 2023-07-27 Röhm Gmbh Polymer foams based on poly(meth)acrylimide
WO2023139194A1 (en) 2022-01-24 2023-07-27 Röhm Gmbh Polymer foams based on blends of poly(vinylidene fluoride) and poly(meth)acrylimide

Family Cites Families (164)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US552104A (en) * 1895-12-31 And herman ellis
BE544324A (de) 1955-01-11
US2904480A (en) 1955-06-06 1959-09-15 Grace W R & Co Polyethylene
US2948666A (en) * 1956-11-21 1960-08-09 Gen Electric Irradiation process
US2946666A (en) * 1957-10-29 1960-07-26 Lewis C Eymann Apparatus for ammoniation of phosphate materials
NL91090C (de) 1957-11-02 1958-12-15
US3563869A (en) 1957-11-05 1971-02-16 Grace W R & Co Irradiated polyethylene
US3022543A (en) 1958-02-07 1962-02-27 Grace W R & Co Method of producing film having improved shrink energy
US2948866A (en) 1958-10-24 1960-08-09 Cie Ind Des Telephones Adjustable correcting networks
US3057791A (en) 1959-07-06 1962-10-09 Phillips Petroleum Co Radiation curing of polymers
US3090770A (en) 1960-04-26 1963-05-21 Grace W R & Co Blended polyethylene compositions of improved clarity and method of making same
US3162623A (en) 1961-12-26 1964-12-22 Du Pont Crosslinking of polymers with nitrogen fluorides
US3297641A (en) 1964-01-17 1967-01-10 Grace W R & Co Process for cross-linking polyethylene
DE1241994B (de) 1964-01-31 1967-06-08 Glanzstoff Ag Verfahren zur Absaettigung von Doppelbindungen in Polyolefinen
DE1669649B2 (de) 1966-05-27 1971-05-19 Badische Anilin- & Soda-Fabrik Ag, 6700 Ludwigshafen Verfahren zum herstellen feinteiliger schaumfoermiger olefin polymerisate mit hoher waermestandfestigkeit
US3832827A (en) 1967-12-18 1974-09-03 J Lemelson Container forming and filling apparatus
BE794718Q (fr) 1968-12-20 1973-05-16 Dow Corning Ltd Procede de reticulation d'olefines
JPS4810618B1 (de) 1969-03-10 1973-04-05
US3758273A (en) 1970-04-03 1973-09-11 Gillette Co Processes for sterilizing polypropylene objects
JPS526314B2 (de) 1971-11-01 1977-02-21
US4055769A (en) 1972-03-21 1977-10-25 Conrad Sander Method and apparatus for curing, a coating on a substrate
US3944536A (en) 1973-06-18 1976-03-16 E. I. Du Pont De Nemours & Company Exceptionally rigid and tough ultrahigh molecular weight linear polyethylene
US3944538A (en) 1973-10-02 1976-03-16 Miklos Bodanszky Process and apparatus for the synthesis of peptides not linked to polymers
DE2447627C3 (de) 1974-10-05 1980-06-26 Dr. Rudolf Kuerner Chemische Spezialprodukte Inh. Dr. Rudolf Kuerner, 6380 Bad Homburg Antimikrobielles Präparat
US4055862A (en) * 1976-01-23 1977-11-01 Zimmer Usa, Inc. Human body implant of graphitic carbon fiber reinforced ultra-high molecular weight polyethylene
AU523866B2 (en) 1978-04-18 1982-08-19 Du Pont Canada Inc. Manufacture of film
US4138382A (en) 1978-05-01 1979-02-06 Dow Corning Corporation Hydrophilic, water-swellable, crosslinked, copolymer gel and prosthesis employing same
US4241463A (en) 1978-10-16 1980-12-30 Precision Cast Specialties, Inc. Prosthetic implant device
US4281420A (en) 1979-02-15 1981-08-04 Raab S Bone connective prostheses adapted to maximize strength and durability of prostheses-bone cement interface; and methods of forming same
WO1980002671A1 (en) 1979-06-06 1980-12-11 Nat Res Dev Polymer processing
US4455691A (en) 1979-10-03 1984-06-26 Minnesota Mining And Manufacturing Company Silicone gel filled prosthesis
US5017627A (en) 1980-10-09 1991-05-21 National Research Development Corporation Composite material for use in orthopaedics
DE3131812C2 (de) * 1981-08-12 1983-06-16 Hewing GmbH & Co, 4434 Ochtrup Verfahren zur Herstellung von Formlingen aus durch Bestrahlen mit Elektronenstrahlen vernetzten Polyolefin-Formmassen
JPS5829841A (ja) 1981-08-14 1983-02-22 Asahi Chem Ind Co Ltd 改良されたポリエチレン組成物
JPS58157830A (ja) 1982-03-12 1983-09-20 Nitto Electric Ind Co Ltd 滑りシ−トの製造法
US4483333A (en) 1982-06-01 1984-11-20 Wrf/Aquaplast Corporation Orthopedic cast
US4586995A (en) 1982-09-17 1986-05-06 Phillips Petroleum Company Polymer and irradiation treatment method
US4816517A (en) 1982-09-29 1989-03-28 Vulkor, Incorporated Crosslinked polymer interdispersions containing polyolefin and method of making
DE3476980D1 (en) 1983-03-23 1989-04-13 Toa Nenryo Kogyo Kk Oriented polyethylene film and method of manufacture
DE3312543A1 (de) 1983-04-07 1984-10-11 Bayer Ag, 5090 Leverkusen 2,2-dimethyl-3-(2-halogen-vinyl)-cyclopropancarbonsaeureester, verfahren zu ihrer herstellung und ihre verwendung als schaedlingsbekaempfungsmittel
CA1240101A (en) 1983-05-06 1988-08-09 Michael J. Pappas Multi-component prosthesis with increased wall flexibility facilitating component assembly
US4518552A (en) 1983-11-09 1985-05-21 Mitsuboshi Belting Ltd. Method of producing accurately sized material of ultra high molecular weight polyethylene
GB8332952D0 (en) 1983-12-09 1984-01-18 Ward I M Polymer irradiation
GB8333032D0 (en) 1983-12-10 1984-01-18 Bp Chem Int Ltd Orientated polyolefins
US4587163A (en) 1984-03-06 1986-05-06 Zachariades Anagnostis E Preparation of ultra high molecular weight polyethylene morphologies of totally fused particles with superior mechanical performance
US4539374A (en) 1984-03-21 1985-09-03 E. I. Du Pont De Nemours And Company Polyolefin with improved processing properties
JPS61501616A (ja) 1984-03-30 1986-08-07 オステオニクス・バイオマテリアルズ・インコーポレーテッド 整形外科用器具およびその製造方法
EP0157601B1 (de) 1984-03-30 1991-05-08 National Research Development Corporation Rohrförmige Gegenstände
EP0161802B1 (de) 1984-04-13 1990-06-27 National Research Development Corporation Verfahren zum Verformen im festen Zustand
IN164745B (de) 1984-05-11 1989-05-20 Stamicarbon
EP0169259A1 (de) 1984-07-25 1986-01-29 Surgical Patent Products Inc. Ltd. Gefässprothesen für trockene Aufbewahrung, Verfahren zur Behandlung und ihre Verwendung in Chirurgie
US4944974A (en) 1984-10-24 1990-07-31 Zachariades Anagnostis E Composite structures of ultra-high-molecular-weight polymers, such as ultra-high-molecular-weight polyethylene products, and method of producing such structures
US4655769A (en) 1984-10-24 1987-04-07 Zachariades Anagnostis E Ultra-high-molecular-weight polyethylene products including vascular prosthesis devices and methods relating thereto and employing pseudo-gel states
US5160472A (en) 1984-10-24 1992-11-03 Zachariades Anagnostis E Method of producing composite structures of ultra-high-molecular-weight polymers, such as ultra-high-molecular-weight polyethylene products
IN166935B (de) 1985-01-31 1990-08-11 Himont Inc
US4950151A (en) 1985-01-31 1990-08-21 Zachariades Anagnostic E Rolling die for producing high modulus products
ATE88196T1 (de) 1985-01-31 1993-04-15 Himont Inc Polypropylen mit freier langkettenverzweigung, verfahren zur herstellung und verwendung davon.
US4820466A (en) 1985-01-31 1989-04-11 Zachariades Anagnostis E Process for obtaining ultra-high modulus products
JPS61204372A (ja) 1985-03-06 1986-09-10 Univ Osaka 電子線による異種原子の固体内注入を利用した材料の非晶質化方法
FR2578780B1 (fr) 1985-03-12 1987-08-14 Commissariat Energie Atomique Piece en polyolefine de haut poids moleculaire, notamment pour prothese articulaire, et son procede de fabrication par forgeage en matrice fermee
GB2172744B (en) 1985-03-23 1989-07-19 Stc Plc Semiconductor devices
DE3545116A1 (de) 1985-05-17 1986-11-20 Transaktor KB International, Göteborg Flasche fuer wassernotverpflegung und verfahren zur herstellung einer flasche mit wassernotverpflegung
US4701288A (en) 1985-06-05 1987-10-20 Bausch & Lomb Incorporated Method of making articles of dissimilar polymer compositions
JPS6274364A (ja) 1985-09-27 1987-04-06 株式会社　ニツシヨ− 医療用具
US4876049A (en) 1985-11-21 1989-10-24 Nippon Petrochemicals Co., Ltd. Method for preparing molded articles of ultra-high molecular weight polyethylene
CA1279167C (en) 1985-11-30 1991-01-22 Mitsui Chemicals, Incorporated Molecularly oriented, silane-crosslinked ultra-high- molecular-weight polyethylene molded article and process for preparation thereof
US4682656A (en) 1986-06-20 1987-07-28 Otis Engineering Corporation Completion apparatus and method for gas lift production
US4965846A (en) 1986-08-11 1990-10-23 Baxter International Inc. Pivot pin bearing/seal with loose eyelet especially suited for disposable continuous flow blood filtration system cartridges
US4743493A (en) 1986-10-06 1988-05-10 Spire Corporation Ion implantation of plastics
US4828827A (en) 1986-12-12 1989-05-09 Ethicon, Inc. Process for augmenting soft tissue with cross-linked polyvinyl pyrrolidone
US4888369A (en) 1987-01-21 1989-12-19 Himont Incorporated Polypropylene composition resistant to high energy radiation, and radiation sterilized articles therefrom
JP2541567B2 (ja) 1987-07-21 1996-10-09 三井石油化学工業株式会社 補強用繊維材料
GB2207436B (en) 1987-07-24 1991-07-24 Nat Research And Dev Corp The Solid phase deformation process
JPS6467326A (en) 1987-09-09 1989-03-14 Toa Nenryo Kogyo Kk Manufacture of crosslinking oriented polyethylene film
FR2631832B1 (fr) 1988-05-24 1994-05-27 Unirec Procede pour reduire le coefficient de frottement et l'usure entre une piece metallique et une piece a base d'un polymere ou copolymere organique et son application a des protheses articulaires
US5047446A (en) 1988-07-22 1991-09-10 Himont Incorporated Thermal treatment of irradiated propylene polymer material
US5014494A (en) 1988-09-27 1991-05-14 Sherwood Medical Company Method of sterilizing medical articles
US5264214A (en) 1988-11-21 1993-11-23 Collagen Corporation Composition for bone repair
GB8827967D0 (en) 1988-11-30 1989-01-05 Ward I M Die-free drawing
US5478906A (en) 1988-12-02 1995-12-26 E. I. Du Pont De Nemours And Company Ultrahigh molecular weight linear polyethylene and articles thereof
WO1990006139A1 (en) 1988-12-02 1990-06-14 E.I. Du Pont De Nemours And Company Ultrahigh molecular weight linear polyethylene, articles and processes of manufacture
BR8907795A (pt) 1988-12-02 1991-08-27 Du Pont Processo para produzir artigos moldados de polietileno linear de peso molecular ultra elevado
JP2590015B2 (ja) 1989-02-15 1997-03-12 三田工業株式会社 トナー像現像装置
US5030402A (en) 1989-03-17 1991-07-09 Zachariades Anagnostis E Process for producing a new class of ultra-high-molecular-weight polyethylene orthopaedic prostheses with enhanced mechanical properties
CA2021814C (en) 1989-07-25 2002-04-02 James A. Davidson Zirconium alloy-based prosthesis with zirconium oxide or zirconium nitride coating
DE3929163A1 (de) 1989-09-02 1991-03-07 Bayer Ag Sekundaere aminogruppen aufweisende copolymerisate, ein verfahren zu ihrer herstellung und ihre verwendung als bindemittel oder bindemittelkomponente
US5024670A (en) 1989-10-02 1991-06-18 Depuy, Division Of Boehringer Mannheim Corporation Polymeric bearing component
US5037928A (en) 1989-10-24 1991-08-06 E. I. Du Pont De Nemours And Company Process of manufacturing ultrahigh molecular weight linear polyethylene shaped articles
US5160677A (en) 1989-12-15 1992-11-03 United States Surgical Corporation Pressurized powder support for treating processes
CA2031406C (en) 1989-12-21 2002-05-28 Paolo Galli Graft copolymers of polyolefins and a method of producing same
US5153039A (en) 1990-03-20 1992-10-06 Paxon Polymer Company, L.P. High density polyethylene article with oxygen barrier properties
US5200439A (en) * 1990-04-13 1993-04-06 Mitsui Toatsu Chemicals, Inc. Method for increasing intrinsic viscosity of syndiotactic polypropylene
US5130376A (en) 1990-04-23 1992-07-14 Hercules Incorporated UHMWPE/styrenic molding compositions with improved flow properties and impact strength
US5236563A (en) 1990-06-18 1993-08-17 Advanced Surface Technology Inc. Surface-modified bioabsorbables
US5133757A (en) 1990-07-31 1992-07-28 Spire Corporation Ion implantation of plastic orthopaedic implants
US5352732A (en) 1990-08-07 1994-10-04 E. I. Du Pont De Nemours And Company Homogeneous, high modulus ultrahigh molecular weight polyethylene composites and processes for the preparation thereof
US5210130A (en) * 1990-08-07 1993-05-11 E. I. Du Pont De Nemours And Company Homogeneous, high modulus ultrahigh molecular weight polyethylene composites and processes for the preparation thereof
US5180484A (en) 1990-08-27 1993-01-19 Uop Caustic free liquid/liquid process for sweeting a sour hydrocarbon fraction
US5236669A (en) 1990-09-12 1993-08-17 E. I. Du Pont De Nemours And Company Pressure vessel
US5702448A (en) 1990-09-17 1997-12-30 Buechel; Frederick F. Prosthesis with biologically inert wear resistant surface
DE4030564A1 (de) 1990-09-27 1992-04-02 Hoechst Ag Pfropfpolymer auf basis von ultrahochmolekularem polyethylen
US5160484A (en) 1990-09-28 1992-11-03 Cranston Print Works Company Paper saturant
US5192323A (en) 1990-11-05 1993-03-09 Zimmer, Inc. Method of surface hardening orthopedic implant devices
US5178812A (en) 1990-11-28 1993-01-12 E. I. Du Pont De Nemours And Company Method of making composites having improved surface properties
US5137688A (en) 1990-11-29 1992-08-11 General Electric Company Irradiated articles molded from polycarbonate-polyamide blends
US5059196A (en) 1991-03-07 1991-10-22 Dow Corning Wright Corporation Femoral prosthesis holder/driver tool and method of implantation using same
DE4110705C1 (de) * 1991-04-03 1992-10-22 Degussa Ag, 6000 Frankfurt, De
US5292584A (en) 1991-04-11 1994-03-08 E. I. Du Pont De Nemours And Company Ultrahigh molecular weight polyethylene and lightly-filled composites thereof
US5508319A (en) 1991-06-21 1996-04-16 Montell North America Inc. High melt strength, ethylene polymer, process for making it, and use thereof
US5439949A (en) * 1991-08-21 1995-08-08 Rexene Corporation Propylene compositions with improved resistance to thermoforming sag
US5972444A (en) 1991-10-15 1999-10-26 The Dow Chemical Company Polyolefin compositions with balanced shrink properties
US5334640A (en) 1992-04-08 1994-08-02 Clover Consolidated, Ltd. Ionically covalently crosslinked and crosslinkable biocompatible encapsulation compositions and methods
US5236583A (en) 1992-05-20 1993-08-17 Wang Yiu Te High-pressure/vacuum operated apparatus for sewage and mud disposal
US5468842A (en) 1992-06-23 1995-11-21 E. I. Du Pont De Nemours And Company Annealed linear high density polyethylene and preparation thereof
US5296583A (en) 1992-07-09 1994-03-22 University Of Michigan Calcification-resistant synthetic biomaterials
US5238563A (en) 1992-07-29 1993-08-24 Exxon Research & Engineering Company Multi-element housing
US5505984A (en) 1993-01-21 1996-04-09 England; Garry L. Method for forming biocompatible components using an isostatic press
US5253732A (en) * 1993-02-22 1993-10-19 Daniels Danny R Portable folding tree stand
US5443519A (en) 1993-04-22 1995-08-22 Implex Corporation Prosthetic ellipsoidal acetabular cup
US5414049A (en) 1993-06-01 1995-05-09 Howmedica Inc. Non-oxidizing polymeric medical implant
US5435723A (en) 1993-08-18 1995-07-25 O'brien; Gary R. Endosseous dental implant system
AU7634094A (en) 1993-08-20 1995-03-21 Smith & Nephew Richards Inc. Self-reinforced ultra-high molecular weight polyethylene composites
US5549700A (en) 1993-09-07 1996-08-27 Ortho Development Corporation Segmented prosthetic articulation
US5496312A (en) 1993-10-07 1996-03-05 Valleylab Inc. Impedance and temperature generator control
US5449145A (en) 1993-10-08 1995-09-12 Surgin Surgical Instrumentation, Inc. Valve device for controlling flows in surgical applications
US5407623A (en) 1994-01-06 1995-04-18 Polteco, Inc. Process for obtaining ultra-high modulus line products with enhanced mechanical properties
US5593719A (en) 1994-03-29 1997-01-14 Southwest Research Institute Treatments to reduce frictional wear between components made of ultra-high molecular weight polyethylene and metal alloys
US5515590A (en) 1994-07-19 1996-05-14 University Of Kentucky Research Foundation Method for reducing the generation of wear particulates from an implant
US5709020A (en) 1994-07-19 1998-01-20 University Of Kentucky Research Foundation Method for reducing the generation of wear particulates from an implant
US5508079A (en) 1994-08-15 1996-04-16 Owens-Corning Fiberglas Technology, Inc. Conformable insulation assembly
US5545453A (en) 1994-08-15 1996-08-13 Owens Corning Fiberglas Technology, Inc. Conformable insulation assembly
EP0729981B1 (de) * 1994-09-21 2002-03-20 Bmg Incorporated Polyethylenguss mit ultrahohem molekulargewicht für künstliche verbindungen und verfahren zu dessen herstellung
US5420367A (en) 1994-09-27 1995-05-30 E. I. Du Pont De Nemours And Company Polymers of vinyl(perfluorocyclopropane)
US5507804A (en) 1994-11-16 1996-04-16 Alcon Laboratories, Inc. Cross-linked polyethylene oxide coatings to improve the biocompatibility of implantable medical devices
US5609638A (en) 1994-11-29 1997-03-11 Zimmer, Inc. Reinforced polyethylene for articular surfaces
JP3681396B2 (ja) 1994-11-30 2005-08-10 インプラント・イノヴェーションズ・インコーポレーテッド インプラント表面調製
US5625858A (en) 1995-01-18 1997-04-29 Canon Kabushiki Kaisha Contact charging member, process for producing same and electrophotographic apparatus using same
CA2166450C (en) 1995-01-20 2008-03-25 Ronald Salovey Chemically crosslinked ultrahigh molecular weight polyethylene for artificial human joints
AU727279B2 (en) 1995-01-20 2000-12-07 Orthopaedic Hospital Chemically crosslinked ultrahigh molecular weight polyethylene for artificial human joints
US20050125074A1 (en) * 1995-01-20 2005-06-09 Ronald Salovey Crosslinking of polyethylene for low wear using radiation and thermal treatments
US5609643A (en) 1995-03-13 1997-03-11 Johnson & Johnson Professional, Inc. Knee joint prosthesis
US5577368A (en) * 1995-04-03 1996-11-26 Johnson & Johnson Professional, Inc. Method for improving wear resistance of polymeric bioimplantable components
BR9609754A (pt) 1995-07-26 1999-03-02 Minnesota Mining & Mfg Composição termoplástica reticulável por radiação artigos de transferência térmica e gráfico e processo para produzir um artigo gráfico
US5674293A (en) 1996-01-19 1997-10-07 Implant Sciences Corp. Coated orthopaedic implant components
JP3840499B2 (ja) 1996-01-22 2006-11-01 ザ・ダウ・ケミカル・カンパニー 向上した特性を示すポリオレフィンエラストマーブレンド物
ATE300964T1 (de) 1996-02-13 2005-08-15 Massachusetts Inst Technology Bestrahlte und schmeltzbehandelte ultrahoch molekulare polyethylen prothesen
US8865788B2 (en) 1996-02-13 2014-10-21 The General Hospital Corporation Radiation and melt treated ultra high molecular weight polyethylene prosthetic devices
US5879400A (en) 1996-02-13 1999-03-09 Massachusetts Institute Of Technology Melt-irradiated ultra high molecular weight polyethylene prosthetic devices
US5753182A (en) 1996-02-14 1998-05-19 Biomet, Inc. Method for reducing the number of free radicals present in ultrahigh molecular weight polyethylene orthopedic components
US5721334A (en) 1996-02-16 1998-02-24 Newyork Society For The Ruptured And Crippled Maintaining The Hospital For Special Surgery Process for producing ultra-high molecular weight low modulus polyethylene shaped articles via controlled pressure and temperature and compositions and articles produced therefrom
US6228900B1 (en) 1996-07-09 2001-05-08 The Orthopaedic Hospital And University Of Southern California Crosslinking of polyethylene for low wear using radiation and thermal treatments
DE69737325T2 (de) 1996-07-09 2007-11-22 University Of Southern California, Los Angeles Vernetzung von polyethylen zur verringerung der abnutzung unter anwendung von strahlung und thermischer behandlung
US6017975A (en) 1996-10-02 2000-01-25 Saum; Kenneth Ashley Process for medical implant of cross-linked ultrahigh molecular weight polyethylene having improved balance of wear properties and oxidation resistance
AU4986497A (en) 1996-10-15 1998-05-11 Orthopaedic Hospital, The Wear resistant surface-gradient cross-linked polyethylene
US5798417A (en) 1996-10-15 1998-08-25 E. I. Du Pont De Nemours And Company (Fluorovinyl ether)-grafted high-surface-area polyolefins and preparation thereof
US5879407A (en) 1997-07-17 1999-03-09 Waggener; Herbert A. Wear resistant ball and socket joint
US6692679B1 (en) * 1998-06-10 2004-02-17 Depuy Orthopaedics, Inc. Cross-linked molded plastic bearings
DE69822470T2 (de) 1998-11-12 2005-01-20 Takiron Co. Ltd. Bioabbaubares, absorbierbares Formgedächtnismaterial
US6245196B1 (en) 1999-02-02 2001-06-12 Praxair Technology, Inc. Method and apparatus for pulp yield enhancement
US6245276B1 (en) 1999-06-08 2001-06-12 Depuy Orthopaedics, Inc. Method for molding a cross-linked preform
US6184265B1 (en) 1999-07-29 2001-02-06 Depuy Orthopaedics, Inc. Low temperature pressure stabilization of implant component
US6143232A (en) 1999-07-29 2000-11-07 Bristol-Meyers Squibb Company Method of manufacturing an articulating bearing surface for an orthopaedic implant
US6318158B1 (en) 2000-03-01 2001-11-20 Coulter International Corp. Sample preparation and delivery system employing external sonicator
EP2275052A1 (de) 2000-04-27 2011-01-19 Orthopaedic Hospital Oxidationsbeständige und abnutzungsbeständige Polyethylene für den Ersatz menschlicher Gelenke und Herstellungsverfahren dafür

Also Published As

Publication number Publication date
US8008365B2 (en) 2011-08-30
JP4187712B2 (ja) 2008-11-26
WO1998001085A1 (en) 1998-01-15
EP1795212A3 (de) 2007-09-05
EP0935446A1 (de) 1999-08-18
EP2319546A1 (de) 2011-05-11
US20070100017A1 (en) 2007-05-03
EP1795212A2 (de) 2007-06-13
JP2000514481A (ja) 2000-10-31
EP0935446B1 (de) 2007-02-07
US20040266902A1 (en) 2004-12-30
DE69737325T2 (de) 2007-11-22
US20080133021A1 (en) 2008-06-05
EP0935446A4 (de) 2001-12-19
JP2005161029A (ja) 2005-06-23
US20050048096A1 (en) 2005-03-03
US20020037944A1 (en) 2002-03-28
CA2260241A1 (en) 1998-01-15
US6800670B2 (en) 2004-10-05
CA2260241C (en) 2010-09-14
AU3655197A (en) 1998-02-02
US8003709B2 (en) 2011-08-23
US20070100016A1 (en) 2007-05-03

Similar Documents

Publication Publication Date Title
DE69737325D1 (de) Vernetzung von polyethylen zur verringerung der abnutzung unter anwendung von strahlung und thermischer behandlung
DE59902314D1 (de) Oligomerisiertes Organopolysiloxan-Cokondensat, dessen Herstellung und dessen Verwendung zur Behandlung von Oberflächen
ATE331505T1 (de) Behandlung einer hämoglobinstörung
DE69830728D1 (de) Arzneimittel zur behandlung von häufigem wasserlassen und harninkontinenz
DE69838338D1 (de) Verwendung von antimykotica zur topischen behandlung von pilz-induzierten schleimhautentzündungen
DE69712003D1 (de) Modifikation von xylanase zur Verbesserung von Thermophilicität, alkophilicität und thermostabilität
DE69703649D1 (de) Behandlung von deagglomerierten teilchen mit plasmaaktivierter spezies
DE69704877T2 (de) Verwendung von anti-mikrotubuli mitteln zur behandlung und prophylaxe der multiplen sclerose
ID24473A (id) Komposisi dan metode untuk perawatan tanaman dengan kimia eksogen
DE69920019D1 (de) Behandlung von mineralfüllstoffen mit phosphaten, diese füllstoffe und deren verwendung
DE69123942T2 (de) Spreizspektrumsübertragungssystem mit Direktsequenz und mit Frequenzmodulation zur Erzielung der Spektrumsspreizung
FI972165A (fi) Aerogeelipitoinen komposiittimateriaali, menetelmä sen valmistamiseksi ja sen käyttö
DE69739758D1 (de) Vakzine zur behandlung von lymphomen und leukämie
ATE334966T1 (de) 3-(amino- oder aminoalkyl)pyridinon-derivate und ihre anwendung bei der behandlung von mit hiv zusammenhängenden krankheiten
ATE253383T1 (de) Behandlung von in der luft enthaltenen mikroorganismen
DE69725843D1 (de) Mittel zur verwendung in der phototherapeutischen behandlung proliferativer hautstörungen
DE69711311D1 (de) Vorrichtung zur thermischen Behandlung von Gewebe
EE9900111A (et) Laustekstiilkomposiit, selle valmistamise meetod ja kasutamine
DE69831334T2 (de) Oxydierungszusammensetzung zur anwendung in der behandlung von keratinischen fasern
ATE218862T1 (de) Verwendung von 1-hydroxy-2-pyridonen zur behandlung von hautinfektionen
ID23906A (id) Komposisi dan metode untuk perlakuan tanaman dengan bahan kimia eksogen
DE69727240D1 (de) Kombinationen enthaltend vx478, zidovudin und 3tc zur behandlung von hiv
DE69434093D1 (de) Substanz mit immunonodulierender wirkung und zur verringerung der disfunktion des gewebezellenregelungssystems
DE60027429D1 (de) Dihydrobenzodiazepinen und deren verwendung zur behandlung von dyslipidämien
DE69825319D1 (de) Präparat zur vorbeugung und behandlung von entzündungen

Legal Events

Date Code Title Description
8381 Inventor (new situation)

Inventor name: SHEN, FU-WEN, WALNUT, CALIF., US

Inventor name: MCKELLOP, HARRY, A., LOS ANGELES, CALIF., US

Inventor name: SALOVEY, RONALD, RANCHO PALOS VERDES, CALIF., US

8363 Opposition against the patent