DE69638369D1 - Die Unterhaut als ein Wachstumssubstrat für Zellen - Google Patents

Die Unterhaut als ein Wachstumssubstrat für Zellen

Info

Publication number
DE69638369D1
DE69638369D1 DE69638369T DE69638369T DE69638369D1 DE 69638369 D1 DE69638369 D1 DE 69638369D1 DE 69638369 T DE69638369 T DE 69638369T DE 69638369 T DE69638369 T DE 69638369T DE 69638369 D1 DE69638369 D1 DE 69638369D1
Authority
DE
Germany
Prior art keywords
cells
growth substrate
subcutaneous tissue
subcutaneous
tissue
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69638369T
Other languages
English (en)
Inventor
Stephen F Badylak
George Boder
Sherry Voytik
Robert J Demeter
John K Critser
Chi Liu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
METHODIST HEALTH GROUP Inc
Purdue Research Foundation
Original Assignee
METHODIST HEALTH GROUP Inc
Purdue Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by METHODIST HEALTH GROUP Inc, Purdue Research Foundation filed Critical METHODIST HEALTH GROUP Inc
Application granted granted Critical
Publication of DE69638369D1 publication Critical patent/DE69638369D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0655—Chondrocytes; Cartilage
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/34—Internal compartments or partitions
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M25/00—Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
    • C12M25/02—Membranes; Filters
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0068—General culture methods using substrates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0676—Pancreatic cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0679—Cells of the gastro-intestinal tract
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/30—Organic components
    • C12N2500/32—Amino acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/30—Organic components
    • C12N2500/38—Vitamins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/90—Substrates of biological origin, e.g. extracellular matrix, decellularised tissue
    • C12N2533/92—Amnion; Decellularised dermis or mucosa
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S623/00—Prosthesis, i.e. artificial body members, parts thereof, or aids and accessories therefor
    • Y10S623/915—Method or apparatus for preparing biological material
DE69638369T 1995-02-10 1996-02-09 Die Unterhaut als ein Wachstumssubstrat für Zellen Expired - Lifetime DE69638369D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/386,452 US5695998A (en) 1995-02-10 1995-02-10 Submucosa as a growth substrate for islet cells

Publications (1)

Publication Number Publication Date
DE69638369D1 true DE69638369D1 (de) 2011-06-16

Family

ID=23525638

Family Applications (2)

Application Number Title Priority Date Filing Date
DE69638369T Expired - Lifetime DE69638369D1 (de) 1995-02-10 1996-02-09 Die Unterhaut als ein Wachstumssubstrat für Zellen
DE69630206T Expired - Lifetime DE69630206D1 (de) 1995-02-10 1996-02-09 Die unterhaut als ein wachstumssubstrat für zellen

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE69630206T Expired - Lifetime DE69630206D1 (de) 1995-02-10 1996-02-09 Die unterhaut als ein wachstumssubstrat für zellen

Country Status (8)

Country Link
US (4) US5695998A (de)
EP (2) EP0809691B1 (de)
JP (2) JP4054059B2 (de)
AR (1) AR000921A1 (de)
AU (1) AU719160B2 (de)
CA (1) CA2212704A1 (de)
DE (2) DE69638369D1 (de)
WO (1) WO1996024661A1 (de)

Families Citing this family (244)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6334872B1 (en) 1994-02-18 2002-01-01 Organogenesis Inc. Method for treating diseased or damaged organs
US6551618B2 (en) 1994-03-15 2003-04-22 University Of Birmingham Compositions and methods for delivery of agents for neuronal regeneration and survival
US6485723B1 (en) * 1995-02-10 2002-11-26 Purdue Research Foundation Enhanced submucosal tissue graft constructs
US20020095218A1 (en) 1996-03-12 2002-07-18 Carr Robert M. Tissue repair fabric
US6043092A (en) * 1996-03-18 2000-03-28 University Of Pittsburgh Cell culture media for mammalian cells
US6171344B1 (en) * 1996-08-16 2001-01-09 Children's Medical Center Corporation Bladder submucosa seeded with cells for tissue reconstruction
ES2306841T3 (es) * 1996-08-23 2008-11-16 Cook Biotech, Inc. Protesis para injertos con base de colageno.
US6666892B2 (en) 1996-08-23 2003-12-23 Cook Biotech Incorporated Multi-formed collagenous biomaterial medical device
US8716227B2 (en) * 1996-08-23 2014-05-06 Cook Biotech Incorporated Graft prosthesis, materials and methods
US20060025786A1 (en) * 1996-08-30 2006-02-02 Verigen Transplantation Service International (Vtsi) Ag Method for autologous transplantation
US6241981B1 (en) * 1996-09-16 2001-06-05 Purdue Research Foundation Composition and method for repairing neurological tissue
EP0944647B1 (de) 1996-12-10 2008-11-12 Purdue Research Foundation Submukosaextrakte
JP4152444B2 (ja) * 1996-12-10 2008-09-17 パーデュー・リサーチ・ファウンデーション 新規な診断用具としての胃粘膜下組織
US6696270B2 (en) 1996-12-10 2004-02-24 Purdue Research Foundation Gastric submucosal tissue as a novel diagnostic tool
WO1998025635A1 (en) * 1996-12-10 1998-06-18 Purdue Research Foundation Submucosal tissue inhibition of neoplastic cell growth
CA2300260C (en) * 1997-09-11 2011-05-10 Purdue Research Foundation Galactosidase modified submucosal tissue
US7070607B2 (en) 1998-01-27 2006-07-04 The Regents Of The University Of California Bioabsorbable polymeric implants and a method of using the same to create occlusions
AU772827B2 (en) * 1998-02-27 2004-05-06 Purdue Research Foundation, Of Office Of Technology Commercialization Purdue University Shape retaining gel compositions
US6264992B1 (en) * 1998-02-27 2001-07-24 Purdue Research Foundation Submucosa as a growth substrate for cells
JP4341049B2 (ja) * 1998-06-05 2009-10-07 オルガノジェネシス インク． 生物工学により作成したチューブ状移植片補綴
CA2334228C (en) * 1998-06-05 2010-09-28 Organogenesis Inc. Bioengineered vascular graft support prostheses
DE69940507D1 (de) * 1998-06-05 2009-04-16 Organogenesis Inc Biotechnisch erzeugte gefässprothese für die implantation
EP1082071B1 (de) * 1998-06-05 2009-03-04 Organogenesis Inc. Verfahren zur herstellung einer gefässprothese
JP5226914B2 (ja) * 1998-06-19 2013-07-03 ライフセル コーポレイション 粒状無細胞組織マトリックス
US6933326B1 (en) * 1998-06-19 2005-08-23 Lifecell Coporation Particulate acellular tissue matrix
US6458109B1 (en) 1998-08-07 2002-10-01 Hill-Rom Services, Inc. Wound treatment apparatus
CA2342589A1 (en) * 1998-09-11 2000-03-23 Purdue Research Foundation Enhanced submucosal tissue graft constructs
US6506599B1 (en) * 1999-10-15 2003-01-14 Tai-Wook Yoon Method for culturing langerhans islets and islet autotransplantation islet regeneration
ES2249928T3 (es) * 1998-11-19 2006-04-01 Organogenesis Inc. Constructos de tejido manipulado mediante bioingenieria y metodos para producirlos y utilizarlos.
JP2002531181A (ja) 1998-12-01 2002-09-24 クック・バイオテック・インコーポレーテッド 多型コラーゲン性バイオマテリアル医療装置
US8882850B2 (en) 1998-12-01 2014-11-11 Cook Biotech Incorporated Multi-formed collagenous biomaterial medical device
US6918396B1 (en) 1998-12-01 2005-07-19 Purdue Research Foundation Method for vocal cord reconstruction
US6365385B1 (en) 1999-03-22 2002-04-02 Duke University Methods of culturing and encapsulating pancreatic islet cells
US6303355B1 (en) 1999-03-22 2001-10-16 Duke University Method of culturing, cryopreserving and encapsulating pancreatic islet cells
US6521191B1 (en) * 1999-07-07 2003-02-18 Novosis Ag Permeation cell for in vitro determination of skin permeation of pharmaceutical drugs
DE29911790U1 (de) * 1999-07-07 1999-09-30 Novosis Pharma Ag Permeationszelle zur in-vitro-Bestimmung der Hautpermeation von pharmazeutischen Wirkstoffen
US20020116063A1 (en) * 1999-08-02 2002-08-22 Bruno Giannetti Kit for chondrocyte cell transplantation
CA2378618C (en) 1999-08-06 2009-10-06 Cook Biotech Incorporated Tubular graft construct
US6764462B2 (en) 2000-11-29 2004-07-20 Hill-Rom Services Inc. Wound treatment apparatus
US6824533B2 (en) 2000-11-29 2004-11-30 Hill-Rom Services, Inc. Wound treatment apparatus
US6576265B1 (en) 1999-12-22 2003-06-10 Acell, Inc. Tissue regenerative composition, method of making, and method of use thereof
ES2749801T3 (es) 1999-12-22 2020-03-23 Acell Inc Composición para regeneración de tejidos
US20040043006A1 (en) * 2002-08-27 2004-03-04 Badylak Stephen F. Tissue regenerative composition
US6579538B1 (en) 1999-12-22 2003-06-17 Acell, Inc. Tissue regenerative compositions for cardiac applications, method of making, and method of use thereof
US6428802B1 (en) 1999-12-29 2002-08-06 Children's Medical Center Corp. Preparing artificial organs by forming polylayers of different cell populations on a substrate
US6376244B1 (en) 1999-12-29 2002-04-23 Children's Medical Center Corporation Methods and compositions for organ decellularization
US6368859B1 (en) 1999-12-29 2002-04-09 Children's Medical Center Corporation Methods and compositions for producing a fascial sling
JP2004509658A (ja) 2000-05-22 2004-04-02 コフィー，アーサー，シー． 小腸粘膜下組織と真空包帯の組合せとその使用方法
DE10026482A1 (de) * 2000-05-29 2001-12-13 Augustinus Bader Verfahren zur Herstellung eines bioartifiziellen Transplantats
US20080182293A1 (en) * 2000-07-14 2008-07-31 Transform Pharmaceuticals, Inc. Computerized control of high-throughput transdermal experimental processing and digital analysis of comparative samples
US6852526B2 (en) * 2000-07-14 2005-02-08 Transform Pharmaceuticals, Inc. Transdermal assay with magnetic clamp
US7172859B2 (en) * 2000-07-14 2007-02-06 Transform Pharmaceuticals, Inc. System and method for optimizing tissue barrier transfer of compounds
DE60123960T2 (de) * 2000-07-14 2007-04-26 Transform Pharmaceuticals, Inc., Lexington System und verfahren zum optimieren des gewebebarrieretransfers von verbindungen
US6638312B2 (en) 2000-08-04 2003-10-28 Depuy Orthopaedics, Inc. Reinforced small intestinal submucosa (SIS)
US8366787B2 (en) 2000-08-04 2013-02-05 Depuy Products, Inc. Hybrid biologic-synthetic bioabsorbable scaffolds
JP5433840B2 (ja) * 2000-09-09 2014-03-05 ザ・リサーチ・ファウンデーション・フォー・ザ・ステイト・ユニヴァーシティ・オブ・ニューヨーク 転移癌細胞を単離するための方法および組成物、ならびに癌の転移能の測定におけるその使用
CA2422852C (en) * 2000-09-18 2012-06-26 Organogenesis Inc. Methods for treating a patient using a bioengineered flat sheet graft prostheses
US6740501B2 (en) * 2000-09-27 2004-05-25 Becton, Dickinson And Company Coated membrane for assessing the invasive capacity of a cell
US6685681B2 (en) 2000-11-29 2004-02-03 Hill-Rom Services, Inc. Vacuum therapy and cleansing dressing for wounds
US6855135B2 (en) 2000-11-29 2005-02-15 Hill-Rom Services, Inc. Vacuum therapy and cleansing dressing for wounds
CA2430989A1 (en) 2000-12-06 2002-06-13 Robert J. Hariri Method of collecting placental stem cells
US20080152629A1 (en) * 2000-12-06 2008-06-26 James Edinger Placental stem cell populations
US7078033B2 (en) * 2001-12-07 2006-07-18 The Board Of Regents Of The University Of Oklahoma Urinary tract tissue graft compositions and methods for producing same
US7122200B2 (en) * 2000-12-08 2006-10-17 The Board Of Regents Of The University Of Oklahoma Vitro engineered, regenerated urinary tract tissue compositions and methods for producing same
US7344712B2 (en) * 2000-12-08 2008-03-18 The Board Of Regent Of The University Of Oklahoma Urinary tract tissue graft compositions and methods for producing same
US20070122388A1 (en) * 2000-12-08 2007-05-31 Kropp Bradley P Tissue graft compositions and methods for producing same
EP2316919B1 (de) * 2001-02-14 2015-10-07 Anthrogenesis Corporation Post-partum Säugetier-Plazenta, deren Verwendung und daraus gewonnene Stammzellen
CA2438904C (en) * 2001-02-23 2012-09-04 The University Of Pittsburgh Rapid preparation of stem cell matrices for use in tissue and organ treatment and repair
US6706520B2 (en) 2001-06-13 2004-03-16 Kehan Han Assessment of invasive potential of tumor cells
WO2003002165A1 (en) 2001-06-28 2003-01-09 Cook Biotech Incorporated Graft prosthesis devices containing renal capsule collagen
US7914808B2 (en) 2001-07-16 2011-03-29 Depuy Products, Inc. Hybrid biologic/synthetic porous extracellular matrix scaffolds
US7819918B2 (en) 2001-07-16 2010-10-26 Depuy Products, Inc. Implantable tissue repair device
WO2003007784A2 (en) 2001-07-16 2003-01-30 Depuy Products, Inc. Meniscus regeneration device and method
US7163563B2 (en) 2001-07-16 2007-01-16 Depuy Products, Inc. Unitary surgical device and method
US8025896B2 (en) 2001-07-16 2011-09-27 Depuy Products, Inc. Porous extracellular matrix scaffold and method
EP1416880B1 (de) 2001-07-16 2011-03-02 DePuy Products, Inc. Gerät zur reparatur von knorpelmaterial
JP4197158B2 (ja) 2001-07-16 2008-12-17 デピュイ・プロダクツ・インコーポレイテッド 天然に発生する生物学的に誘導されている材料による装置
WO2003007786A2 (en) 2001-07-16 2003-01-30 Depuy Products, Inc. Porous delivery scaffold and method
AU2002316696B2 (en) 2001-07-16 2007-08-30 Depuy Products, Inc. Cartilage repair and regeneration scaffold and method
US20110091353A1 (en) * 2001-09-24 2011-04-21 Wilson Burgess Methods for Sterilizing Tissue
EP1450878A1 (de) 2001-10-11 2004-09-01 Hill-Rom Services, Inc. Abfallbehälter für die unterdrucktherapie
EP1444994B1 (de) 2001-10-15 2014-07-30 Japan Science and Technology Agency Verfahren zur bildung von normalem regeneriertem gewebe; das normale regenerierte gewebe und verfahren zur kalibrierung der sensitivität und dergleichen
CA2464661C (en) 2001-10-26 2011-11-29 Cook Biotech Incorporated Medical graft device with meshed structure
US7534927B2 (en) 2001-12-26 2009-05-19 Hill-Rom Services, Inc. Vacuum bandage packing
WO2003057307A1 (en) 2001-12-26 2003-07-17 Hill-Rom Services, Inc. Wound vacuum therapy dressing kit
EP1478313B2 (de) 2001-12-26 2018-03-07 KCI Medical Resources Gelüfteter vakuumverband
US8394371B2 (en) 2002-02-11 2013-03-12 Neocutis Sa Compositions for the treatment of skin conditions, disorders or diseases and methods of making and using the same
US20100254900A1 (en) * 2002-03-18 2010-10-07 Campbell Phil G Biocompatible polymers and Methods of use
US8529956B2 (en) 2002-03-18 2013-09-10 Carnell Therapeutics Corporation Methods and apparatus for manufacturing plasma based plastics and bioplastics produced therefrom
CA2474512A1 (en) * 2002-03-22 2003-10-09 Bayer Pharmaceuticals Corporation Method for producing pseudo islets
WO2003080143A1 (fr) * 2002-03-25 2003-10-02 Kaken Pharmaceutical Co., Ltd. Materiau de base de reconstruction de tissu ou d'organe contenant une matrice tissulaire sans cellule et un facteur de croissance cellulaire
US9144583B2 (en) 2002-03-29 2015-09-29 Tissue Genesis, Inc. Cell separation apparatus and methods of use
US8202725B2 (en) * 2004-12-23 2012-06-19 Tissue Genesis Incorporated Cell sodding method and apparatus
US8168848B2 (en) 2002-04-10 2012-05-01 KCI Medical Resources, Inc. Access openings in vacuum bandage
US20040166169A1 (en) * 2002-07-15 2004-08-26 Prasanna Malaviya Porous extracellular matrix scaffold and method
US7896856B2 (en) 2002-08-21 2011-03-01 Robert Petrosenko Wound packing for preventing wound closure
EP1556501A4 (de) * 2002-10-28 2009-04-08 Transform Pharmaceuticals Inc Transdermaler assay mit magnetischerklemme
US7449307B2 (en) * 2002-10-28 2008-11-11 Transform Pharmaceuticals, Inc. Raised surface assay plate
US6908760B2 (en) * 2002-10-28 2005-06-21 Transform Pharmaceuticals, Inc. Raised surface assay plate
KR101042448B1 (ko) 2002-11-26 2011-06-16 안트로제네시스 코포레이션 세포요법제, 세포요법제 단위 및 이를 이용한 치료방법
MXPA05008445A (es) * 2003-02-13 2005-10-18 Anthrogenesis Corp Uso de sangre del cordon umbilical para tratar individuos que tienen una enfermedad, un trastorno o una afeccion.
US20040175366A1 (en) * 2003-03-07 2004-09-09 Acell, Inc. Scaffold for cell growth and differentiation
US20040176855A1 (en) * 2003-03-07 2004-09-09 Acell, Inc. Decellularized liver for repair of tissue and treatment of organ deficiency
US7067123B2 (en) 2003-04-29 2006-06-27 Musculoskeletal Transplant Foundation Glue for cartilage repair
US7901457B2 (en) 2003-05-16 2011-03-08 Musculoskeletal Transplant Foundation Cartilage allograft plug
US7488348B2 (en) 2003-05-16 2009-02-10 Musculoskeletal Transplant Foundation Cartilage allograft plug
EP1660642A4 (de) * 2003-06-16 2006-12-20 Zephan Biopharmaceuticals Inc Verfahren zur herstellung eines transplantierbaren produkts zur behandlung von hautdefekten
CA2530490A1 (en) * 2003-06-25 2005-01-13 Stephen F. Badylak Conditioned matrix compositions for tissue restoration
AU2004270239C1 (en) 2003-09-04 2011-07-07 Cook Biotech Incorporated Extracellular matrix composite materials, and manufacture and use thereof
US20050054099A1 (en) * 2003-09-04 2005-03-10 Cedars Sinai Medical Center Matrix derived from whole organ
GB0321337D0 (en) * 2003-09-11 2003-10-15 Massone Mobile Advertising Sys Method and system for distributing advertisements
EP1694328A4 (de) * 2003-12-02 2010-02-17 Celgene Corp Verfahren und zusammensetzungen zur behandlung und versorgung von hämoglobinopathie und anämie
ES2396689T3 (es) 2003-12-11 2013-02-25 Isto Technologies Inc. Sistema de cartílago particulado
WO2005077433A1 (en) * 2004-02-09 2005-08-25 Cook Biotech Incorporated Stent graft devices having collagen coating
WO2005097190A2 (en) * 2004-03-26 2005-10-20 Celgene Corporation Systems and methods for providing a stem cell bank
US7569233B2 (en) 2004-05-04 2009-08-04 Depuy Products, Inc. Hybrid biologic-synthetic bioabsorbable scaffolds
US20050249772A1 (en) * 2004-05-04 2005-11-10 Prasanna Malaviya Hybrid biologic-synthetic bioabsorbable scaffolds
US20050288796A1 (en) * 2004-06-23 2005-12-29 Hani Awad Native soft tissue matrix for therapeutic applications
US8257715B1 (en) 2004-08-26 2012-09-04 University Of Notre Dame Tissue vaccines and uses thereof
US20060058238A1 (en) 2004-09-15 2006-03-16 Lee Laurent-Applegate Fetal skin cell protein compositions for the treatment of skin conditions, disorders or diseases and methods of making and using the same
US7837740B2 (en) 2007-01-24 2010-11-23 Musculoskeletal Transplant Foundation Two piece cancellous construct for cartilage repair
US7513866B2 (en) 2004-10-29 2009-04-07 Depuy Products, Inc. Intestine processing device and associated method
US7905826B2 (en) 2004-11-03 2011-03-15 Cook Incorporated Methods for modifying vascular vessel walls
US8329202B2 (en) 2004-11-12 2012-12-11 Depuy Products, Inc. System and method for attaching soft tissue to an implant
WO2006062976A2 (en) 2004-12-07 2006-06-15 Cook Incorporated Methods for modifying vascular vessel walls
US7354627B2 (en) 2004-12-22 2008-04-08 Depuy Products, Inc. Method for organizing the assembly of collagen fibers and compositions formed therefrom
US20060206139A1 (en) * 2005-01-19 2006-09-14 Tekulve Kurt J Vascular occlusion device
US7851189B2 (en) * 2005-03-07 2010-12-14 Boston Scientific Scimed, Inc. Microencapsulated compositions for endoluminal tissue engineering
WO2006102063A2 (en) * 2005-03-19 2006-09-28 Cook Biotech Incorporated Prosthetic implants including ecm composite material
AU2006262178B2 (en) 2005-06-21 2012-07-05 Cook Biotech, Inc. Implantable graft to close a fistula
US20060292227A1 (en) * 2005-06-23 2006-12-28 Mcpherson Timothy B Extracellular matrix material particles and methods of preparation
US7815926B2 (en) 2005-07-11 2010-10-19 Musculoskeletal Transplant Foundation Implant for articular cartilage repair
EP1902128A4 (de) * 2005-07-12 2009-02-25 Tissue Genesis Inc Vorrichtung und verfahren zur herstellung von gewebetransplantaten
US7595062B2 (en) 2005-07-28 2009-09-29 Depuy Products, Inc. Joint resurfacing orthopaedic implant and associated method
EP2093256A3 (de) 2005-07-28 2009-10-14 Carnegie Mellon University Biokompatible Polymere und Verwendungsverfahren
US8480757B2 (en) 2005-08-26 2013-07-09 Zimmer, Inc. Implants and methods for repair, replacement and treatment of disease
US8921109B2 (en) 2005-09-19 2014-12-30 Histogenics Corporation Cell-support matrix having narrowly defined uniformly vertically and non-randomly organized porosity and pore density and a method for preparation thereof
NZ597304A (en) 2005-10-13 2013-06-28 Anthrogenesis Corp Immunomodulation using placental stem cells
US20070190165A1 (en) * 2005-10-21 2007-08-16 Brey Eric M Tissue-specific basement membrane gels
US9308252B2 (en) 2005-10-27 2016-04-12 Cook Biotech, Inc. Extracellular matrix materials as vaccine adjuvants for diseases associated with infectious pathogens or toxins
US8802113B2 (en) * 2005-10-27 2014-08-12 University Of Notre Dame Extracellular matrix cancer vaccine adjuvant
US8778360B2 (en) * 2005-10-27 2014-07-15 University Of Notre Dame Extracellular matrix cancer vaccine adjuvant
US8778362B2 (en) * 2005-10-27 2014-07-15 University Of Notre Dame Anti-tumor/cancer heterologous acellular collagenous preparations and uses thereof
JP5550235B2 (ja) 2005-12-29 2014-07-16 アントフロゲネシス コーポレーション 胎盤幹細胞集団
AU2006332679A1 (en) 2005-12-29 2007-07-12 Anthrogenesis Corporation Co-culture of placental stem cells and stem cells from a second source
US20070166396A1 (en) * 2006-01-06 2007-07-19 University Of Pittsburgh Extracellular matrix based gastroesophageal junction reinforcement device
US8974542B2 (en) 2006-06-27 2015-03-10 University of Pittsburgh—of the Commonwealth System of Higher Education Biodegradable elastomeric patch for treating cardiac or cardiovascular conditions
WO2008008266A2 (en) * 2006-07-07 2008-01-17 University Of Pittsburgh- Of The Commonwealth System Of Higher Education Biohybrid elastomeric scaffolds and methods of use thereof
US20080109070A1 (en) * 2006-08-10 2008-05-08 Wagner William R Biodegradable elastomeric scaffolds containing microintegrated cells
US8529961B2 (en) 2006-10-17 2013-09-10 Carmell Therapeutics Corporation Methods and apparatus for manufacturing plasma based plastics and bioplastics produced therefrom
CN101616698A (zh) 2006-10-23 2009-12-30 库克生物科技公司 组分特性增强的处理的ecm材料
WO2008060973A1 (en) * 2006-11-10 2008-05-22 Vance Products Incorporated D/B/A Cook Urological Incorporated Graft for hysterotomy closure
US7871440B2 (en) 2006-12-11 2011-01-18 Depuy Products, Inc. Unitary surgical device and method
US8163549B2 (en) 2006-12-20 2012-04-24 Zimmer Orthobiologics, Inc. Method of obtaining viable small tissue particles and use for tissue repair
US8343536B2 (en) 2007-01-25 2013-01-01 Cook Biotech Incorporated Biofilm-inhibiting medical products
CN103356711A (zh) * 2007-02-12 2013-10-23 人类起源公司 利用胎盘干细胞治疗炎性疾病
JP2010518812A (ja) * 2007-02-12 2010-06-03 アンスロジェネシス コーポレーション 接着性胎盤幹細胞由来の肝細胞および軟骨細胞、ならびにｃｄ３４＋、ｃｄ４５−胎盤幹細胞の濃縮細胞集団
WO2008109407A2 (en) 2007-03-02 2008-09-12 University Of Pittsburgh-Of The Commonwealth System Of Higher Education Extracellular matrix-derived gels and related methods
US8435551B2 (en) 2007-03-06 2013-05-07 Musculoskeletal Transplant Foundation Cancellous construct with support ring for repair of osteochondral defects
US20100172830A1 (en) * 2007-03-29 2010-07-08 Cellx Inc. Extraembryonic Tissue cells and method of use thereof
WO2008128075A1 (en) 2007-04-12 2008-10-23 Isto Technologies, Inc. Compositions and methods for tissue repair
US20080279833A1 (en) * 2007-05-10 2008-11-13 Matheny Robert G Laminate sheet articles for tissue regeneration
EP3456357A1 (de) 2007-06-29 2019-03-20 Stelic Institute Of Regenerative Medicine, Stelic Institute & Co. Verfahren zur fixierung und expression einer physiologisch aktiven substanz
US9068162B2 (en) * 2007-08-17 2015-06-30 Wake Forest University Health Sciences Keratin biomaterials for cell culture and methods of use
US20090082816A1 (en) 2007-09-20 2009-03-26 Graham Matthew R Remodelable orthopaedic spacer and method of using the same
US20090136553A1 (en) * 2007-09-25 2009-05-28 Gerlach Jorg C Triggerably dissolvable hollow fibers for controlled delivery
KR20160092062A (ko) * 2007-09-26 2016-08-03 안트로제네시스 코포레이션 인간 태반 관류액으로부터의 혈관형성 세포
US20100135964A1 (en) * 2007-09-27 2010-06-03 Alvarado Carlos A Tissue grafting method
US9023342B2 (en) 2007-09-27 2015-05-05 Carlos A. Alvarado Tissue grafting method
AU2008307633C1 (en) 2007-09-28 2015-04-30 Celularity Inc. Tumor suppression using human placental perfusate and human placenta-derived intermediate natural killer cells
KR20100100855A (ko) * 2007-11-07 2010-09-15 안트로제네시스 코포레이션 조산 합병증의 치료에 있어서의 제대혈의 용도
US8257434B2 (en) 2007-12-18 2012-09-04 Cormatrix Cardiovascular, Inc. Prosthetic tissue valve
US8679176B2 (en) 2007-12-18 2014-03-25 Cormatrix Cardiovascular, Inc Prosthetic tissue valve
US9283266B2 (en) * 2008-02-28 2016-03-15 University Of Notre Dame Metastasis inhibition preparations and methods
WO2009111069A1 (en) 2008-03-05 2009-09-11 Musculoskeletal Transplant Foundation Cancellous constructs, cartilage particles and combinations of cancellous constructs and cartilage particles
US20110184439A1 (en) * 2008-05-09 2011-07-28 University Of Pittsburgh-Of The Commonwealth System Of Higher Education Biological Matrix for Cardiac Repair
WO2010014021A1 (en) 2008-07-30 2010-02-04 Mesynthes Limited Tissue scaffolds derived from forestomach extracellular matrix
JP6169316B2 (ja) * 2008-08-20 2017-07-26 アンスロジェネシス コーポレーション 改良型細胞組成物およびその作製方法
KR20180108887A (ko) * 2008-08-20 2018-10-04 안트로제네시스 코포레이션 단리된 태반 세포를 사용한 뇌졸중 치료
MX2011001992A (es) * 2008-08-22 2011-03-29 Anthrogenesis Corp Metodos y composiciones para el tratamiento de defectos oseos con poblaciones de celulas placentarias.
AU2009288118B2 (en) 2008-09-02 2014-12-11 Allergan, Inc. Threads of hyaluronic acid and/or derivatives thereof, methods of making thereof and uses thereof
US20110190680A1 (en) 2008-09-29 2011-08-04 Yoram Vodovotz Self-Regulating Device for Modulating Inflammation
GB0817990D0 (en) * 2008-10-02 2008-11-05 Reinnervate Ltd Cell culture vessel
RU2562154C2 (ru) * 2008-11-19 2015-09-10 Антродженезис Корпорейшн Амниотические адгезивные клетки
DK2375907T3 (da) * 2008-11-21 2019-06-11 Celularity Inc Behandling af sygdomme, lidelser eller tilstande i lungerne under anvendelse af placentaceller
US9084722B2 (en) 2008-12-05 2015-07-21 University of Pittsburgh—of the Commonwealth System of Higher Education Biologic scaffold for prevention of pulmonary fibrosis
IL196820A0 (en) * 2009-02-01 2009-11-18 Yissum Res Dev Co Devitalized, acellular scaffold matrices derived from micro-organs seeded with various cells
PL3000472T3 (pl) 2009-02-18 2017-09-29 Cormatrix Cardiovascular, Inc. Kompozycje do zapobiegania migotaniu przedsionków i komór
US9277999B2 (en) 2009-02-27 2016-03-08 University of Pittsburgh—of the Commonwealth System of Higher Education Joint bioscaffolds
CA2760889C (en) 2009-05-06 2017-09-19 Hansa Medical Products, Inc. Self-adjusting medical device
US8652500B2 (en) 2009-07-22 2014-02-18 Acell, Inc. Particulate tissue graft with components of differing density and methods of making and using the same
US8298586B2 (en) 2009-07-22 2012-10-30 Acell Inc Variable density tissue graft composition
WO2011022045A2 (en) * 2009-08-17 2011-02-24 Singh Ashok K Apparatus and process for generating and harvesting adult stem cells and fluid associated with it from skin and omentum for medical, cosmetic, and veterinary use
US8716438B2 (en) 2009-10-09 2014-05-06 University of Pittsburgh—of the Commonwealth System of Higher Education Matricryptic ECM peptides for tissue reconstruction
US8846059B2 (en) 2009-12-08 2014-09-30 University Of Notre Dame Extracellular matrix adjuvant and methods for prevention and/or inhibition of ovarian tumors and ovarian cancer
US20110150934A1 (en) * 2009-12-18 2011-06-23 University Of Notre Dame Ovarian Tumor Tissue Cell Preparations/Vaccines for the Treatment/Inhibition of Ovarian Tumors and Ovarian Cancer
WO2011087743A2 (en) 2009-12-22 2011-07-21 University Of Pittsburgh-Of The Commonwealth System Of Higher Education Decellularized adipose cell growth scaffold
ES2646750T3 (es) * 2010-01-26 2017-12-15 Anthrogenesis Corporation Tratamiento de cánceres relacionados con hueso utilizando células madre placentarias
KR20190076060A (ko) 2010-04-07 2019-07-01 안트로제네시스 코포레이션 태반 줄기 세포를 사용한 혈관신생
EP2555783A1 (de) 2010-04-08 2013-02-13 Anthrogenesis Corporation Behandlung von sarkoidose mithilfe von stammzellen aus der plazenta
WO2011150328A1 (en) 2010-05-27 2011-12-01 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Wet-electrospun biodegradable scaffold and uses therefor
WO2011156338A2 (en) 2010-06-07 2011-12-15 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Methods for modeling hepatic inflammation
CN105713868A (zh) * 2010-07-02 2016-06-29 北卡罗来纳-查佩尔山大学 用于工业规模分散的生物基质支架
WO2012009422A1 (en) 2010-07-13 2012-01-19 Anthrogenesis Corporation Methods of generating natural killer cells
WO2012024390A2 (en) 2010-08-17 2012-02-23 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Biohybrid composite scaffold
DK2608777T3 (en) 2010-08-24 2019-10-28 Univ California Compositions and Methods for Cardiac Therapy
US8969315B2 (en) 2010-12-31 2015-03-03 Anthrogenesis Corporation Enhancement of placental stem cell potency using modulatory RNA molecules
JP2014533119A (ja) 2011-05-27 2014-12-11 コーマトリックス カーディオバスキュラー， インコーポレイテッドＣｏｒＭａｔｒｉｘ Ｃａｒｄｉｏｖａｓｃｕｌａｒ， Ｉｎｃ． 細胞外マトリックス材料の弁導管及びその作製方法
JP6158175B2 (ja) * 2011-05-27 2017-07-05 デピュイ・シンセス・プロダクツ・インコーポレイテッド バイオ人工近位尿細管システム及びその使用方法
ES2707579T3 (es) 2011-06-01 2019-04-04 Celularity Inc Tratamiento del dolor usando citoblastos placentarios
WO2013055476A1 (en) 2011-09-09 2013-04-18 Anthrogenesis Corporation Treatment of amyotrophic lateral sclerosis using placental stem cells
DK3501558T3 (da) 2011-12-20 2021-03-01 Lifecell Corp Flydbare vævsprodukter
EP2793964B1 (de) 2011-12-20 2019-03-20 LifeCell Corporation Blattförmige tissueprodukte
US9271821B2 (en) 2012-01-24 2016-03-01 Lifecell Corporation Elongated tissue matrices
WO2013162997A1 (en) 2012-04-24 2013-10-31 Lifecell Corporation Functionalized tissue matrices
US20140178343A1 (en) 2012-12-21 2014-06-26 Jian Q. Yao Supports and methods for promoting integration of cartilage tissue explants
AU2014215458A1 (en) 2013-02-05 2015-08-13 Anthrogenesis Corporation Natural killer cells from placenta
US9861662B2 (en) 2013-07-03 2018-01-09 University of Pittsburgh—of the Commonwealth System of Higher Education Bone-derived extra cellular matrix gel
US9878071B2 (en) 2013-10-16 2018-01-30 Purdue Research Foundation Collagen compositions and methods of use
US10286119B2 (en) 2014-01-24 2019-05-14 University of Pittsburgh—of the Commonwealth System of Higher Education Extracellular matrix mesh coating
JP6681872B2 (ja) 2014-03-21 2020-04-15 ユニバーシティ オブ ピッツバーグ −オブ ザ コモンウェルス システム オブ ハイヤー エデュケイション 細胞外マトリクス由来最終滅菌ヒドロゲルの調製方法
US10077420B2 (en) 2014-12-02 2018-09-18 Histogenics Corporation Cell and tissue culture container
WO2016138423A1 (en) 2015-02-27 2016-09-01 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Retrievable self-expanding non-thrombogenic low-profile percutaneous atrioventricular valve prosthesis
JP6974916B2 (ja) 2015-02-27 2021-12-01 ユニバーシティ オブ ピッツバーグ − オブ ザ コモンウェルス システム オブ ハイヤー エデュケイション 多弁尖の弁の電気紡績ステントレス製作のための二重構成要素マンドレル
WO2016172365A1 (en) 2015-04-21 2016-10-27 Purdue Research Foundation Office Of Technology Commercialization Cell-collagen-silica composites and methods of making and using the same
WO2017049167A1 (en) 2015-09-18 2017-03-23 University Of Pittsburgh-Of The Commonwealth System Of Higher Education Non-gelling soluble extracellular matrix with biological activity
WO2017062762A2 (en) 2015-10-07 2017-04-13 Sigmon John C Methods, medical devices and kits for modifying the luminal profile of a body vessel
WO2017151862A1 (en) 2016-03-02 2017-09-08 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Matrix bound nanovesicles and their use
US11331348B2 (en) 2016-04-28 2022-05-17 University of Pittsburgh—of the Commonwealth System of Higher Education Compositions comprising extracellular matrix of primitive animal species and related methods
EP3585313A4 (de) 2017-02-23 2020-12-30 University of Pittsburgh - of The Commonwealth System of Higher Education Zur lebendgeweberegeneration fähige, stentlose biopolymerherzklappe
KR20190120258A (ko) 2017-03-02 2019-10-23 유니버시티 오브 피츠버그 - 오브 더 커먼웰쓰 시스템 오브 하이어 에듀케이션 식도 염증 치료를 위한 ecm 하이드로겔
AU2018226871B2 (en) 2017-03-02 2023-08-10 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Extracellular matrix (ECM) hydrogel and soluble fraction thereof for the treatment of cancer
US10767164B2 (en) 2017-03-30 2020-09-08 The Research Foundation For The State University Of New York Microenvironments for self-assembly of islet organoids from stem cells differentiation
US11389569B2 (en) 2017-04-03 2022-07-19 University of Pittsburgh—of the Commonwealth System of Higher Education Biodegradable, porous, thermally responsive injectable hydrogel as soft tissue defect filler
WO2018200750A1 (en) 2017-04-25 2018-11-01 Purdue Research Foundation 3-dimensional (3d) tissue-engineered muscle for tissue restoration
WO2018204848A1 (en) 2017-05-05 2018-11-08 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Ocular applications of matrix bound vesicles (mbvs)
US11634716B2 (en) 2017-10-16 2023-04-25 University of Pittsburgh—of the Commonwealth System of Higher Education Genetically modified mesenchymal stem cells for use in cardiovascular prosthetics
KR20210095885A (ko) 2018-11-19 2021-08-03 더 유나이티드 스테이츠 오브 어메리카, 애즈 리프리젠티드 바이 더 세크러테리, 디파트먼트 오브 헬쓰 앤드 휴먼 서비씨즈 생분해성 조직 대체 임플란트 및 그의 용도
KR20210142003A (ko) 2019-03-13 2021-11-23 유니버시티 오브 피츠버그 - 오브 더 커먼웰쓰 시스템 오브 하이어 에듀케이션 음향 세포외 기질 하이드로겔 및 이의 용도
GB201916135D0 (en) 2019-11-06 2019-12-18 Ucl Business Plc Extracellular matrix gels, and organoid cultures comprising the same
US11826490B1 (en) 2020-12-29 2023-11-28 Acell, Inc. Extracellular matrix sheet devices with improved mechanical properties and method of making
CA3220602A1 (en) 2021-05-28 2022-12-01 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Methods to generate macular, central and peripheral retinal pigment epithelial cells
CA3220433A1 (en) 2021-05-28 2022-12-01 Arvydas Maminishkis Biodegradable tissue scaffold with secondary matrix to host weakly adherent cells
WO2023218789A1 (ja) * 2022-05-09 2023-11-16 凸版印刷株式会社 動物組織から幹細胞を回収する方法

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4439521A (en) * 1981-10-21 1984-03-27 Ontario Cancer Institute Method for producing self-reproducing mammalian pancreatic islet-like structures
US5352483A (en) * 1983-03-24 1994-10-04 Viscosuisse S.A. Preadhered melt spun spin-drawn polyester filaments
US4801299A (en) * 1983-06-10 1989-01-31 University Patents, Inc. Body implants of extracellular matrix and means and methods of making and using such implants
CA1295796C (en) * 1984-03-27 1992-02-18 Conrad Whyne Biodegradable matrix and methods for producing same
US4743552A (en) * 1984-09-26 1988-05-10 Sloan-Kettering Institute For Cancer Research Method for growth in tissue culture of normal colonic epithelial cells and method for determination of preneoplastic color cells
US4829000A (en) * 1985-08-30 1989-05-09 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Reconstituted basement membrane complex with biological activity
US5266480A (en) * 1986-04-18 1993-11-30 Advanced Tissue Sciences, Inc. Three-dimensional skin culture system
GB8618374D0 (en) * 1986-07-28 1986-09-03 Hsc Res Dev Corp Biological vascular prostheses
US5604106A (en) * 1987-06-05 1997-02-18 Us Commerce Method for detecting carcinoma
JPH0814679B2 (ja) * 1987-11-16 1996-02-14 富士写真光機株式会社 沈胴式ズームレンズ付カメラ
US4902508A (en) * 1988-07-11 1990-02-20 Purdue Research Foundation Tissue graft composition
US4956178A (en) * 1988-07-11 1990-09-11 Purdue Research Foundation Tissue graft composition
US4912057A (en) * 1989-06-13 1990-03-27 Cancer Diagnostics, Inc. Cell chamber for chemotaxis assay
US5275828A (en) * 1989-11-08 1994-01-04 Hooper Oswald E Treatment and/or a method of treating equine viral and bacterial infections
US5336616A (en) * 1990-09-12 1994-08-09 Lifecell Corporation Method for processing and preserving collagen-based tissues for transplantation
NZ239893A (en) * 1990-09-25 1993-11-25 Hoechst Japan A method for introducing a foreign dna into a cell
WO1992015676A1 (en) * 1991-03-08 1992-09-17 The Salk Institute For Biological Studies Somatic cell gene therapy
CA2112112A1 (en) * 1991-06-24 1993-01-07 Ann J. Brothers Hormone-secreting cells maintained in long-term culture
US5281422A (en) * 1991-09-24 1994-01-25 Purdue Research Foundation Graft for promoting autogenous tissue growth
US5478739A (en) * 1992-10-23 1995-12-26 Advanced Tissue Sciences, Inc. Three-dimensional stromal cell and tissue culture system
US5275826A (en) * 1992-11-13 1994-01-04 Purdue Research Foundation Fluidized intestinal submucosa and its use as an injectable tissue graft
US5352463A (en) * 1992-11-13 1994-10-04 Badylak Steven F Tissue graft for surgical reconstruction of a collagenous meniscus and method therefor

Also Published As

Publication number Publication date
EP1449916A2 (de) 2004-08-25
EP0809691A4 (de) 2000-06-21
AR000921A1 (es) 1997-08-27
EP0809691A1 (de) 1997-12-03
US5753267A (en) 1998-05-19
US6087157A (en) 2000-07-11
JPH10513363A (ja) 1998-12-22
CA2212704A1 (en) 1996-08-15
DE69630206D1 (de) 2003-11-06
US5695998A (en) 1997-12-09
JP2007105031A (ja) 2007-04-26
AU4921096A (en) 1996-08-27
EP1449916A3 (de) 2004-12-22
JP4054059B2 (ja) 2008-02-27
JP4054352B2 (ja) 2008-02-27
AU719160B2 (en) 2000-05-04
EP0809691B1 (de) 2003-10-01
WO1996024661A1 (en) 1996-08-15
EP1449916B1 (de) 2011-05-04
US5866414A (en) 1999-02-02

Similar Documents

Publication Publication Date Title
DE69638369D1 (de) Die Unterhaut als ein Wachstumssubstrat für Zellen
ID23668A (id) Turunan asam ariloksiarilsulfonilamino hidroksamat
ID21140A (id) Metode produksi asam akrilat
ID19926A (id) Proses untuk produksi asam tereftalat murni
DE69602122T2 (de) Flache Zelle
DE69606397D1 (de) Wasserabweisendes agens für zellen
DE59610788D1 (de) Mikroelektroden-anordnung
DE69904532D1 (de) Herstellungsverfahren für dünne Solarzellen
ID28833A (id) Turunan asam 3-aril-2-hidroksipropionat
DE69606352T2 (de) Additvthaltige Kathoden für elektrochemische Zellen
ID26222A (id) Hidroksamida asam(4-arilsulfonilamino)-tetrahidropiran-4-karboksilat
DE69603416T2 (de) Elektrochemischer Immunobiosensor
DE69604091D1 (de) Koextrudierte monofilamente
ID26978A (id) Turunan-turunan asam aminometilkarboksilat
DE69838129D1 (de) Herstellungsverfahren für gewebe
ID27390A (id) Pembuatan asam akrilat
IT1284656B1 (it) Cella elettrolitica
DE59601373D1 (de) Prismatische, galvanische Zelle
BR9610196A (pt) Pilha eletroquímica
DE69617614T2 (de) Ein werkzeug zur herstellung von verbindungsstellen zwischen plattenförmigen teilen
DE59610180D1 (de) Mikroskopstativ, insbesondere für ein Operationsmikroskop
ID25547A (id) Proses pembuatan asam l-askorbat
DE69737004D1 (de) Kristallwachstumsmodifikatoren für Perylenpigmente
ID30119A (id) Proses pembuatan asam aminokarboksilat
DE69623245T2 (de) Elektrochemisches Abscheideverfahren