DE69624047T2 - Im unteren Teil des Verdauungstrakts freisetzende pharmazeutische Zubereitung in Form einer beschichteten Kapsel - Google Patents

Im unteren Teil des Verdauungstrakts freisetzende pharmazeutische Zubereitung in Form einer beschichteten Kapsel

Info

Publication number
DE69624047T2
DE69624047T2 DE69624047T DE69624047T DE69624047T2 DE 69624047 T2 DE69624047 T2 DE 69624047T2 DE 69624047 T DE69624047 T DE 69624047T DE 69624047 T DE69624047 T DE 69624047T DE 69624047 T2 DE69624047 T2 DE 69624047T2
Authority
DE
Germany
Prior art keywords
pharmaceutical preparation
digestive tract
low
polymer film
coated capsule
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69624047T
Other languages
English (en)
Other versions
DE69624047D1 (de
Inventor
Harumi Hatano
Takahiro Ito
Takashi Ishibashi
Hiroyuki Yoshino
Masakazu Mizobe
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tanabe Seiyaku Co Ltd
Original Assignee
Tanabe Seiyaku Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tanabe Seiyaku Co Ltd filed Critical Tanabe Seiyaku Co Ltd
Publication of DE69624047D1 publication Critical patent/DE69624047D1/de
Application granted granted Critical
Publication of DE69624047T2 publication Critical patent/DE69624047T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4891Coated capsules; Multilayered drug free capsule shells

Landscapes

  • Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE69624047T 1995-07-20 1996-07-18 Im unteren Teil des Verdauungstrakts freisetzende pharmazeutische Zubereitung in Form einer beschichteten Kapsel Expired - Fee Related DE69624047T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP18365595 1995-07-20

Publications (2)

Publication Number Publication Date
DE69624047D1 DE69624047D1 (de) 2002-11-07
DE69624047T2 true DE69624047T2 (de) 2003-08-14

Family

ID=16139614

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69624047T Expired - Fee Related DE69624047T2 (de) 1995-07-20 1996-07-18 Im unteren Teil des Verdauungstrakts freisetzende pharmazeutische Zubereitung in Form einer beschichteten Kapsel

Country Status (13)

Country Link
US (1) US6309666B1 (de)
EP (1) EP0754452B1 (de)
KR (1) KR100389602B1 (de)
CN (1) CN1076964C (de)
AT (1) ATE225165T1 (de)
CA (1) CA2181502C (de)
DE (1) DE69624047T2 (de)
DK (1) DK0754452T3 (de)
ES (1) ES2184846T3 (de)
ID (1) ID17428A (de)
PT (1) PT754452E (de)
SG (1) SG80553A1 (de)
TW (1) TW514533B (de)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102004046102A1 (de) * 2004-09-23 2006-04-06 Mars Inc. Indikatorgranulat
US10653631B2 (en) 2011-09-07 2020-05-19 Roland SAUR-BROSCH Optimal colon targeting technology
US10799460B2 (en) 2011-09-07 2020-10-13 Roland SAUR-BROSCH Formulation for the controlled release of one or several substances in the digestive tract of a mammal

Families Citing this family (61)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL336231A1 (en) * 1997-02-13 2000-06-19 Bone Care International System for aimed therapeutic delivery of vitamin d compounds
US20030129194A1 (en) * 1997-02-13 2003-07-10 Bone Care International, Inc. Targeted therapeutic delivery of vitamin D compounds
US20020035071A1 (en) * 1997-07-08 2002-03-21 Josef Pitha Mimicking the metabolic effects of caloric restriction by administration of glucose antimetabolites
US20060116330A1 (en) * 1997-07-08 2006-06-01 The Iams Company Methods of mimicking the metabolic effects of caloric restriction by administration of mannoheptulose
US8563522B2 (en) * 1997-07-08 2013-10-22 The Iams Company Method of maintaining and/or attenuating a decline in quality of life
US6303144B1 (en) 1998-02-10 2001-10-16 Welfide Corporation Preparations with controlled release
UA69413C2 (uk) 1998-05-22 2004-09-15 Брістол-Майерс Сквібб Компані Фармацевтична композиція, яка містить серцевину та ентеросолюбільну оболонку, фармацевтична композиція у вигляді сфероїдальних гранул, спосіб одержання сфероїдальних гранул та спосіб одержання фармацевтичної композиції
US7122207B2 (en) 1998-05-22 2006-10-17 Bristol-Myers Squibb Company High drug load acid labile pharmaceutical composition
UA73092C2 (uk) 1998-07-17 2005-06-15 Брістол-Майерс Сквібб Компані Таблетка з ентеросолюбільним покриттям і спосіб її приготування
AU5758799A (en) * 1998-09-25 2000-04-17 Sankyo Company Limited Hmg-coa reductase inhibitor-containing preparations
AU757343B2 (en) * 1998-09-28 2003-02-20 Capsugel Belgium Nv Enteric and colonic delivery using HPMC capsules
JP2000247911A (ja) 1999-02-26 2000-09-12 Hisamitsu Pharmaceut Co Inc 大腸用吸収促進剤
EP1197228A4 (de) 1999-07-02 2004-03-10 Hisamitsu Pharmaceutical Co Arzneimittel für die behandlung von kolorektalem krebs
AU2001234005B2 (en) * 2000-02-28 2006-01-19 Pharmakodex Limited Improvements in or relating to the delivery of oral drugs
TWI241195B (en) * 2000-04-10 2005-10-11 Shionogi & Co Preventive agent for bile acidic diarrhea
KR100838686B1 (ko) 2000-06-16 2008-06-16 미쯔비시 웰 파마 가부시키가이샤 방출 pH 범위 및/또는 속도 제어 조성물
GB0102342D0 (en) * 2001-01-30 2001-03-14 Smithkline Beecham Plc Pharmaceutical formulation
US7883721B2 (en) * 2001-01-30 2011-02-08 Smithkline Beecham Limited Pharmaceutical formulation
US7842308B2 (en) * 2001-01-30 2010-11-30 Smithkline Beecham Limited Pharmaceutical formulation
US7316819B2 (en) * 2001-03-08 2008-01-08 Unigene Laboratories, Inc. Oral peptide pharmaceutical dosage form and method of production
US20030070584A1 (en) 2001-05-15 2003-04-17 Cynthia Gulian Dip coating compositions containing cellulose ethers
US20030044458A1 (en) 2001-08-06 2003-03-06 Curtis Wright Oral dosage form comprising a therapeutic agent and an adverse-effect agent
US8309118B2 (en) 2001-09-28 2012-11-13 Mcneil-Ppc, Inc. Film forming compositions containing sucralose
JP4031232B2 (ja) * 2001-11-09 2008-01-09 カプスゲル・ジャパン株式会社 新規カプセル
US7101565B2 (en) 2002-02-05 2006-09-05 Corpak Medsystems, Inc. Probiotic/prebiotic composition and delivery method
US20030181488A1 (en) * 2002-03-07 2003-09-25 Boehringer Ingelheim Pharma Gmbh & Co. Kg Administration form for the oral application of 3-[(2-{[4-(hexyloxycarbonylamino-imino-methyl)-phenylamino]-methyl}-1-methyl-1H-benzimidazol-5-carbonyl)-pyridin-2-yl-amino]-propionic acid ethyl ester and the salts thereof
US6982253B2 (en) * 2002-06-05 2006-01-03 Supergen, Inc. Liquid formulation of decitabine and use of the same
US8168170B2 (en) * 2002-10-03 2012-05-01 The Procter And Gamble Company Compositions having an inner core and at least three surrounding layers
MY148805A (en) * 2002-10-16 2013-05-31 Takeda Pharmaceutical Controlled release preparation
US7320583B2 (en) * 2003-04-16 2008-01-22 Frito-Lay North America, Inc Apparatus and method for producing colored extruded food products
TW200526274A (en) * 2003-07-21 2005-08-16 Smithkline Beecham Plc Pharmaceutical formulations
GB0320522D0 (en) 2003-09-02 2003-10-01 Glaxo Group Ltd Formulation
US8894991B2 (en) * 2003-12-19 2014-11-25 The Iams Company Canine probiotic Lactobacilli
US20050158294A1 (en) * 2003-12-19 2005-07-21 The Procter & Gamble Company Canine probiotic Bifidobacteria pseudolongum
US7785635B1 (en) 2003-12-19 2010-08-31 The Procter & Gamble Company Methods of use of probiotic lactobacilli for companion animals
US20050152884A1 (en) * 2003-12-19 2005-07-14 The Procter & Gamble Company Canine probiotic Bifidobacteria globosum
US8877178B2 (en) * 2003-12-19 2014-11-04 The Iams Company Methods of use of probiotic bifidobacteria for companion animals
TW200539903A (en) 2004-03-12 2005-12-16 Smithkline Beecham Plc Pharmaceutical formulations
US20050283097A1 (en) * 2004-06-18 2005-12-22 Ultrastop Ltd. Devices and methodologies useful in non invasive termination of pregnancy
GB0427456D0 (en) * 2004-12-15 2005-01-19 Phoqus Pharmaceuticals Ltd Formulation for production of capsule shells and capsules
BRPI0611492B1 (pt) * 2005-05-31 2021-10-13 Mars, Incorporated Bifidobactéria probiótica felina
AU2006253006B8 (en) * 2005-05-31 2011-09-15 Alimentary Health Ltd Feline probiotic Lactobacilli
US20070014847A1 (en) * 2005-07-05 2007-01-18 Ahmed Salah U Coated capsules and methods of making and using the same
US20070196399A1 (en) * 2006-02-21 2007-08-23 Shin-Etsu Chemical Co., Ltd. Enteric-coated preparation covered with enteric coating material for site-specific delivery of drug to site within the small intestine
MX2009008166A (es) 2007-02-01 2009-08-12 Iams Company Metodo para disminuir la inflamacion y estres en un mamifero usando antimetabolitos de glucosa, aguacate o extractos de aguacate.
KR101569604B1 (ko) 2007-12-28 2015-11-16 임팩스 라보라토리즈, 인코포레이티드 레보도파 방출 제어형 제제 및 이의 용도
GB0808537D0 (en) 2008-05-12 2008-06-18 Archimedes Dev Ltd Compositions
US9771199B2 (en) 2008-07-07 2017-09-26 Mars, Incorporated Probiotic supplement, process for making, and packaging
WO2010080730A2 (en) * 2009-01-09 2010-07-15 Mayo Foundation For Medical Education And Research Methods and materials for delivering bile acids
US10104903B2 (en) 2009-07-31 2018-10-23 Mars, Incorporated Animal food and its appearance
JP6027532B2 (ja) * 2010-08-25 2016-11-16 セカンド、グラント、ルーファス スパーリング 改良された腸溶性の活性物質送達
DE102011082716A1 (de) * 2011-09-14 2013-03-14 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Indikatorelement mit einer von einer in kontakt zu bringenden substanz abhängigen farbgebung
US10987313B2 (en) 2013-10-07 2021-04-27 Impax Laboratories, Llc Muco-adhesive, controlled release formulations of levodopa and/or esters of levodopa and uses thereof
EP3782614A1 (de) * 2013-10-07 2021-02-24 Impax Laboratories, LLC Mukoadhäsive levodopa-formulierungen mit gesteuerter freisetzung und/oder levodopa-ester und verwendungen davon
WO2017175752A1 (ja) 2016-04-08 2017-10-12 株式会社ダイセル セルロースエステルとその成形体
EP3485879A1 (de) * 2017-11-17 2019-05-22 Maat Pharma Orale pharmazeutische formulierung enthaltend bakterien
CA3098604A1 (en) * 2018-05-03 2019-11-07 M.W. Encap Limited Dosage forms for delivery of medicines to the lower gastrointestinal tract
US20210369625A1 (en) * 2018-10-02 2021-12-02 Qualicaps Co., Ltd. Improved-strength hard capsule and production method for same
KR102106244B1 (ko) * 2019-10-30 2020-05-04 한국광기술원 앵커를 구비하는 캡슐형 광역학 치료장치
US11896719B2 (en) 2022-01-24 2024-02-13 Calliditas Therapeutics Ab Pharmaceutical compositions
WO2023174722A1 (en) * 2022-03-15 2023-09-21 Evonik Operations Gmbh Pre-functionalized hard shell capsule with accelerated drug release at ph value 5 to 5.5

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4012444A (en) * 1969-07-08 1977-03-15 Allen & Hanburys Limited 5-[1-Hydroxy-2-(1-methyl-3-phenylpropyl)aminoethyl] salicylamide and physiologically acceptable acid addition salts thereof
US5188840A (en) * 1985-09-26 1993-02-23 Chugai Seiyaku Kabushiki Kaisha Slow-release pharmaceutical agent
JPS6299322A (ja) 1985-10-24 1987-05-08 Shinjiro Tsuji 硬カプセル剤の新しい剤形
IL77186A0 (en) * 1985-11-29 1986-04-29 Touitou Elka Pharmaceutical insulin composition
DE3812799A1 (de) * 1988-04-16 1989-10-26 Sanol Arznei Schwarz Gmbh Oral zu verabreichende pharmazeutische zubereitung mit kontrollierter wirkstofffreisetzung und verfahren zu deren herstellung
US5252576A (en) * 1988-07-18 1993-10-12 Yamasa Shoyu Kabushiki Kaisha 1-amino-5-halogenouracils, process for their preparation, and central nervous system depressants containing same as active ingredient
ES2062527T3 (es) * 1989-05-11 1994-12-16 Chugai Pharmaceutical Co Ltd Preparacion oral que puede ser liberada en una region apropiada del intestino.
JPH0674206B2 (ja) * 1989-12-28 1994-09-21 田辺製薬株式会社 放出制御型製剤およびその製法
JP2773959B2 (ja) * 1990-07-10 1998-07-09 信越化学工業株式会社 大腸内放出性固形製剤
JP3122478B2 (ja) 1991-02-19 2001-01-09 帝國製薬株式会社 下部消化管放出型経口製剤
JPH0624962A (ja) 1992-07-09 1994-02-01 Green Cross Corp:The 腸溶徐放性製剤
ES2119818T3 (es) 1992-08-13 1998-10-16 Teikoku Seiyaku Kk Preparacion oral para liberacion en el tracto digestivo inferior.
WO1994010983A1 (en) 1992-11-06 1994-05-26 Hisamitsu Pharmaceutical Co., Inc. Peroral pharmaceutical preparation releasable in lower digestive tract
JPH06256166A (ja) 1993-01-06 1994-09-13 ▲寛▼治 ▲高▼田 薬物放出制御製剤
JPH0710745A (ja) 1993-06-22 1995-01-13 Tanabe Seiyaku Co Ltd 放出開始時間制御型腸デリバリー経口製剤

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102004046102A1 (de) * 2004-09-23 2006-04-06 Mars Inc. Indikatorgranulat
DE102004046102B4 (de) * 2004-09-23 2009-09-03 Mars Inc. Indikatorgranulat
US7670845B2 (en) 2004-09-23 2010-03-02 Mars Incorporated Indicator granular material
US10653631B2 (en) 2011-09-07 2020-05-19 Roland SAUR-BROSCH Optimal colon targeting technology
US10799460B2 (en) 2011-09-07 2020-10-13 Roland SAUR-BROSCH Formulation for the controlled release of one or several substances in the digestive tract of a mammal

Also Published As

Publication number Publication date
ID17428A (id) 1997-12-24
ES2184846T3 (es) 2003-04-16
DK0754452T3 (da) 2003-02-03
EP0754452A2 (de) 1997-01-22
DE69624047D1 (de) 2002-11-07
MX9602863A (es) 1997-09-30
CN1142944A (zh) 1997-02-19
SG80553A1 (en) 2001-05-22
EP0754452A3 (de) 1998-01-21
PT754452E (pt) 2003-02-28
CA2181502C (en) 2003-02-11
CA2181502A1 (en) 1997-01-21
US6309666B1 (en) 2001-10-30
CN1076964C (zh) 2002-01-02
ATE225165T1 (de) 2002-10-15
KR970005279A (ko) 1997-02-19
TW514533B (en) 2002-12-21
KR100389602B1 (ko) 2003-09-29
EP0754452B1 (de) 2002-10-02

Similar Documents

Publication Publication Date Title
DE69624047D1 (de) Im unteren Teil des Verdauungstrakts freisetzende pharmazeutische Zubereitung in Form einer beschichteten Kapsel
DK0673645T3 (da) Farmaceutisk præparat til afgivelse af lægemidler i colon
DE3686936D1 (de) Am zielorgan wirkendes enterales abgabesystem.
MX9500885A (es) Preparacion farmaceutica para administracion oral.
BR0315142A (pt) Cápsula, tablete, grânulo ou grânulo fino, e, cápsula de liberação prolongada
ATE251899T1 (de) Pharmazeutische dosierungsform zur freisetzung im colon
IE872110L (en) Oral therapeutic system having systemic action
HU912170D0 (en) Medical preparations for providing controlled feeling of release
DE69619668T2 (de) Pharmazeutische dosisform mit mehrfacher darmlöslicher polymerbeschichtung zur wirkstoffabgabe im kolon
CA2383220A1 (en) Controlled release pellet formulation
AU7534087A (en) Sustained release pharmaceutical compositions in oral dosage form
ATE238774T1 (de) Darreichungsform zur verzögerten, vollständigen wirkstoffabgabe im verdauungstrakt
ATE235232T1 (de) Lutschtablette zur modifizierten freisetzung von wirkstoffen im gastrointestinaltrakt
DE69909316D1 (de) Pharmazeutische formulierung mit omeprazol
DK156289D0 (da) Farmaceutisk praeparat indrettet til kontrolleret afgivelse af aktiv bestanddel
ATE198152T1 (de) Oral anzuwendende arzneizubereitung mit verzögerter wirkstoffabgabe
ATE124255T1 (de) Im dickdarm zerfallende, polypeptide enthaltende orale formulierungen.
DE69622850D1 (de) Perorale zusammensetzung zur kontrollierten freisetzungen in dem unteren teil des gastrointestinaltraktes
SE8803822D0 (sv) Novel dosage form
DE60142305D1 (de) Pharmazeutische zubereitung enthaltend n-ä2-(1,6,7,8-tetrahydro-2h-indenoä5,4 büfuran-8-yl)ethylüpropionamid ummantelt mit einer copolyvidon-enthaltenden, polyäthylenglykolfreien umhüllung
DE69008107T2 (de) Zubereitung mit verzögerter Freigabe eines Hydrochlorids eines basischen Arzneistoffs.
BR9612800A (pt) Forma de dosagem farmacêutica para distribuição colÈnica.

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee