DE69612624T2 - Optisches sensorsystem zur ionenstärkeunabhängigen ph-messung - Google Patents

Optisches sensorsystem zur ionenstärkeunabhängigen ph-messung

Info

Publication number
DE69612624T2
DE69612624T2 DE69612624T DE69612624T DE69612624T2 DE 69612624 T2 DE69612624 T2 DE 69612624T2 DE 69612624 T DE69612624 T DE 69612624T DE 69612624 T DE69612624 T DE 69612624T DE 69612624 T2 DE69612624 T2 DE 69612624T2
Authority
DE
Germany
Prior art keywords
measurement
optical sensor
sensor system
ion strength
strength independent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69612624T
Other languages
English (en)
Other versions
DE69612624D1 (de
Inventor
Steven Mark Barnard
Joseph Berger
Marizel Rouilly
Adrian Waldner
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Novartis AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis AG filed Critical Novartis AG
Publication of DE69612624D1 publication Critical patent/DE69612624D1/de
Application granted granted Critical
Publication of DE69612624T2 publication Critical patent/DE69612624T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/84—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving inorganic compounds or pH
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F220/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride ester, amide, imide or nitrile thereof
    • C08F220/02—Monocarboxylic acids having less than ten carbon atoms; Derivatives thereof
    • C08F220/52—Amides or imides
    • C08F220/54—Amides, e.g. N,N-dimethylacrylamide or N-isopropylacrylamide
    • C08F220/56—Acrylamide; Methacrylamide
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N2021/7769—Measurement method of reaction-produced change in sensor
    • G01N2021/7786—Fluorescence
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/15—Inorganic acid or base [e.g., hcl, sulfuric acid, etc. ]
DE69612624T 1995-10-23 1996-10-11 Optisches sensorsystem zur ionenstärkeunabhängigen ph-messung Expired - Lifetime DE69612624T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH299595 1995-10-23
PCT/EP1996/004426 WO1997015832A1 (en) 1995-10-23 1996-10-11 Optical sensor system for the determination of ph values independently of ionic strength

Publications (2)

Publication Number Publication Date
DE69612624D1 DE69612624D1 (de) 2001-05-31
DE69612624T2 true DE69612624T2 (de) 2001-09-13

Family

ID=4246288

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69612624T Expired - Lifetime DE69612624T2 (de) 1995-10-23 1996-10-11 Optisches sensorsystem zur ionenstärkeunabhängigen ph-messung

Country Status (8)

Country Link
US (2) US6252024B1 (de)
EP (1) EP0862741B1 (de)
JP (1) JP3869855B2 (de)
AU (1) AU705916B2 (de)
CA (1) CA2235343A1 (de)
DE (1) DE69612624T2 (de)
WO (1) WO1997015832A1 (de)
ZA (1) ZA968854B (de)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9201039B2 (en) 2011-06-24 2015-12-01 Endress + Hauser Conducta Gesellschaft für Mess- und Regeltechnik mbH + Co. KG Measuring transducer for determining a measured variable representing a content of H+and/or oh−ions in a measured medium

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JP2000512754A (ja) * 1996-06-12 2000-09-26 ノバルティス アクチエンゲゼルシャフト ウレタンおよび／または尿素基を介してポリマーに結合したフルオレッセインを使用したイオン強度に無関係なｐＨ測定のための光学センサー系
AT407090B (de) * 1998-09-15 2000-12-27 Joanneum Research Forschungsge Opto-chemischer sensor sowie verfahren zu seiner herstellung
WO2000076555A1 (en) * 1999-06-11 2000-12-21 Pro Duct Health, Inc. Gel composition for filing a breast milk duct prior to surgical excision of the duct or other breast tissue
JP2003504622A (ja) * 1999-07-08 2003-02-04 ラジオメーター・メディカル・アクティーゼルスカブ 親水性マトリックス材料を含んでなるセンサー
WO2003031962A2 (en) * 2001-10-05 2003-04-17 Signature Bioscience, Inc. Apparatus and method for determining the complex permittivity of a test solution
ATE408451T1 (de) * 2002-04-03 2008-10-15 Mitsubishi Rayon Co Mikroarray enthaltend gel mit fixierter biosubstanz sowie seine herstellung und verwendung
US7052541B2 (en) * 2002-06-19 2006-05-30 Board Of Regents, The University Of Texas System Color compositions
US8551126B2 (en) * 2002-08-22 2013-10-08 Ams Research Corporation Anastomosis device and related methods
WO2005119223A1 (en) * 2004-04-14 2005-12-15 Bioprocessors Corp. Compositions of matter useful as ph indicators and related methods
CN101036046B (zh) 2004-08-19 2012-02-22 血细胞保存公司 荧光pH检测器系统和相关方法
US8497134B2 (en) * 2004-08-19 2013-07-30 Blood Cell Storage, Inc. Fluorescent detector systems for the detection of chemical perturbations in sterile storage devices
US8183052B2 (en) * 2004-08-19 2012-05-22 Blood Cell Storage, Inc. Methods and apparatus for sterility testing
US20060088722A1 (en) * 2004-10-25 2006-04-27 Aller Robert C Optical pH sensor
US20060105174A1 (en) * 2004-10-25 2006-05-18 The Research Foundation Of State University Of New York Optical pH sensor
US7425235B2 (en) * 2005-02-11 2008-09-16 The Board Of Regents Of The University Of Texas System Color compositions and methods of manufacture
CA2615514A1 (en) * 2005-06-17 2006-12-28 The Board Of Regents Of The University Of Texas System Organic/inorganic lewis acid composite materials
JP5441098B2 (ja) * 2006-09-05 2014-03-12 国立大学法人 東京大学 蛍光性分子温度計
GB2468682B (en) * 2009-03-18 2012-08-15 Univ Dublin City pH sensor device comprising an ionogel
WO2011035161A1 (en) * 2009-09-18 2011-03-24 Provectus Pharmaceuticals, Inc. Process for the synthesis of 4,5,6,7-tetrachloro-3',6'-dihydroxy-2',4',5'7'-tetraiodo-3h-spiro[isobenzofuran-1,9'-xanthen]-3-one (rose bengal) and related xanthenes
US9040307B2 (en) 2011-05-27 2015-05-26 Blood Cell Storage, Inc. Fluorescent pH detector system and related methods
ITMO20110327A1 (it) * 2011-12-19 2013-06-20 Rand Srl Una membrana di rilevamento per rilevare parametri di un fluido oragnico durante lo scorrimento in un circuito extracorporeo
CN112457502B (zh) * 2020-11-26 2022-05-17 大连海事大学 一种复合荧光水凝胶制备方法及其在水中铁离子检测中的应用

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AT381172B (de) 1983-08-26 1986-09-10 Avl Verbrennungskraft Messtech Verfahren zur bestimmung der ionenstaerke einer elektrolytloesung sowie messeinrichtung zur durchfuehrung des verfahrens
US5354825A (en) * 1985-04-08 1994-10-11 Klainer Stanley M Surface-bound fluorescent polymers and related methods of synthesis and use
US4898691A (en) 1988-05-16 1990-02-06 Hoechst Celanese Corporation Organic nonlinear optical media
US4906249A (en) * 1989-02-23 1990-03-06 Medtronic, Inc. Terpolymer composition with bound indicator dye for fiber optic probe
US5132057A (en) * 1989-10-11 1992-07-21 Medex, Inc. Method of making an optical fiber probe
US5273716A (en) * 1991-01-14 1993-12-28 Electric Power Research Institute, Inc. pH optrode
DE69430783T2 (de) * 1993-03-11 2003-02-20 Otsuka Kagaku Kk Spiropyrane, optisch aktive spiropyrane sowie deren verwendung
US5607644A (en) * 1993-06-10 1997-03-04 Optical Sensors Incorporated Optical sensor for the measurement of pH in a fluid, and related sensing compositions and methods
US5387525A (en) * 1993-09-03 1995-02-07 Ciba Corning Diagnostics Corp. Method for activation of polyanionic fluorescent dyes in low dielectric media with quaternary onium compounds
HUT75018A (en) * 1994-05-02 1997-03-28 Ciba Geigy Ag Optical sensor system and their parts and process for determining ph value of electrolyt solutions and their ionic strength
US5986030A (en) * 1997-04-15 1999-11-16 Nalco Chemical Company Fluorescent water soluble polymers

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9201039B2 (en) 2011-06-24 2015-12-01 Endress + Hauser Conducta Gesellschaft für Mess- und Regeltechnik mbH + Co. KG Measuring transducer for determining a measured variable representing a content of H+and/or oh−ions in a measured medium

Also Published As

Publication number Publication date
EP0862741B1 (de) 2001-04-25
JPH11513740A (ja) 1999-11-24
US6303385B2 (en) 2001-10-16
EP0862741A1 (de) 1998-09-09
ZA968854B (en) 1997-04-23
AU705916B2 (en) 1999-06-03
AU7290396A (en) 1997-05-15
WO1997015832A1 (en) 1997-05-01
CA2235343A1 (en) 1997-05-01
US20010018217A1 (en) 2001-08-30
DE69612624D1 (de) 2001-05-31
JP3869855B2 (ja) 2007-01-17
US6252024B1 (en) 2001-06-26

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8328 Change in the person/name/address of the agent

Representative=s name: PFENNING MEINIG & PARTNER GBR, 80339 MUENCHEN

8328 Change in the person/name/address of the agent

Representative=s name: MAIWALD PATENTANWALTSGESELLSCHAFT MBH, 80335 MUENC