DE69518915T2 - Verfahren und vorrichtung zur bilderzeugung von erkranktem gewebe unter verwendung der integrierten autofluoreszenz - Google Patents

Verfahren und vorrichtung zur bilderzeugung von erkranktem gewebe unter verwendung der integrierten autofluoreszenz

Info

Publication number
DE69518915T2
DE69518915T2 DE69518915T DE69518915T DE69518915T2 DE 69518915 T2 DE69518915 T2 DE 69518915T2 DE 69518915 T DE69518915 T DE 69518915T DE 69518915 T DE69518915 T DE 69518915T DE 69518915 T2 DE69518915 T2 DE 69518915T2
Authority
DE
Germany
Prior art keywords
imaging
diseased tissue
integrated autofluorescence
autofluorescence
integrated
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69518915T
Other languages
English (en)
Other versions
DE69518915D1 (de
Inventor
Branko Palcic
Calum Macaulay
Stephen Lam
Bruno Jaggi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novadaq Technologies ULC
Original Assignee
Xillix Technologies Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Xillix Technologies Corp filed Critical Xillix Technologies Corp
Publication of DE69518915D1 publication Critical patent/DE69518915D1/de
Application granted granted Critical
Publication of DE69518915T2 publication Critical patent/DE69518915T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/04—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor combined with photographic or television appliances
    • A61B1/043—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor combined with photographic or television appliances for fluorescence imaging
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/04—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor combined with photographic or television appliances
    • A61B1/05—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor combined with photographic or television appliances characterised by the image sensor, e.g. camera, being in the distal end portion
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0071—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by measuring fluorescence emission
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0082—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes
    • A61B5/0084—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes for introduction into the body, e.g. by catheters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0082—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes
    • A61B5/0084—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes for introduction into the body, e.g. by catheters
    • A61B5/0086—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes for introduction into the body, e.g. by catheters using infrared radiation
    • H—ELECTRICITY
    • H04—ELECTRIC COMMUNICATION TECHNIQUE
    • H04N—PICTORIAL COMMUNICATION, e.g. TELEVISION
    • H04N23/00—Cameras or camera modules comprising electronic image sensors; Control thereof
    • H04N23/50—Constructional details
    • H04N23/555—Constructional details for picking-up images in sites, inaccessible due to their dimensions or hazardous conditions, e.g. endoscopes or borescopes
DE69518915T 1994-03-28 1995-03-24 Verfahren und vorrichtung zur bilderzeugung von erkranktem gewebe unter verwendung der integrierten autofluoreszenz Expired - Lifetime DE69518915T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/218,662 US5590660A (en) 1994-03-28 1994-03-28 Apparatus and method for imaging diseased tissue using integrated autofluorescence
PCT/CA1995/000171 WO1995026673A2 (en) 1994-03-28 1995-03-24 Apparatus and method for imaging diseased tissue using integrated autofluorescence

Publications (2)

Publication Number Publication Date
DE69518915D1 DE69518915D1 (de) 2000-10-26
DE69518915T2 true DE69518915T2 (de) 2001-04-19

Family

ID=22815983

Family Applications (3)

Application Number Title Priority Date Filing Date
DE69535270T Expired - Lifetime DE69535270T2 (de) 1994-03-28 1995-03-24 Verfahren und Vorrichtung zur Bilderzeugung von erkranktem Gewebe unter Verwendung der integrierten Autofluoreszenz
DE69534388T Expired - Lifetime DE69534388T2 (de) 1994-03-28 1995-03-24 Vorrichtung zur Bilderzeugung von erkranktem Gewebe unter verwendung der integrierten Autofluoreszenz
DE69518915T Expired - Lifetime DE69518915T2 (de) 1994-03-28 1995-03-24 Verfahren und vorrichtung zur bilderzeugung von erkranktem gewebe unter verwendung der integrierten autofluoreszenz

Family Applications Before (2)

Application Number Title Priority Date Filing Date
DE69535270T Expired - Lifetime DE69535270T2 (de) 1994-03-28 1995-03-24 Verfahren und Vorrichtung zur Bilderzeugung von erkranktem Gewebe unter Verwendung der integrierten Autofluoreszenz
DE69534388T Expired - Lifetime DE69534388T2 (de) 1994-03-28 1995-03-24 Vorrichtung zur Bilderzeugung von erkranktem Gewebe unter verwendung der integrierten Autofluoreszenz

Country Status (5)

Country Link
US (2) US5590660A (de)
EP (3) EP0920831B1 (de)
JP (3) JP3683271B2 (de)
DE (3) DE69535270T2 (de)
WO (1) WO1995026673A2 (de)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102008011013A1 (de) 2008-02-25 2009-09-03 Labo Tech Labortechnik Gmbh Verfahren und Einrichtung zur komplexen Stoffwechselanalyse
DE102008062650A1 (de) * 2008-12-17 2010-07-15 Carl Zeiss Surgical Gmbh Operationsmikroskop zur Beobachtung einer Infrarot-Fluoreszenz und Verfahren hierzu
DE102012002086A1 (de) * 2012-02-06 2013-08-08 Carl Zeiss Meditec Ag Verfahren zum Untersuchen von biologischem Gewebe und Vorrichtungen zum Untersuchen und Behandeln des Gewebes
DE102015011441A1 (de) * 2015-09-01 2017-03-02 Carl Zeiss Meditec Ag Fluoreszenzlichtdetektionssystem und Mikroskopiesystem
DE102017203452A1 (de) 2017-03-02 2018-09-06 Carl Zeiss Meditec Ag Fluoreszenzbeobachtungssystem

Families Citing this family (506)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5845639A (en) * 1990-08-10 1998-12-08 Board Of Regents Of The University Of Washington Optical imaging methods
US6196226B1 (en) 1990-08-10 2001-03-06 University Of Washington Methods and apparatus for optically imaging neuronal tissue and activity
US6198532B1 (en) 1991-02-22 2001-03-06 Applied Spectral Imaging Ltd. Spectral bio-imaging of the eye
US6304771B1 (en) * 1993-10-29 2001-10-16 The Trustees Of The University Of Pennsylvania Systems and methods for imaging fluorophores
US5590660A (en) * 1994-03-28 1997-01-07 Xillix Technologies Corp. Apparatus and method for imaging diseased tissue using integrated autofluorescence
US5697373A (en) * 1995-03-14 1997-12-16 Board Of Regents, The University Of Texas System Optical method and apparatus for the diagnosis of cervical precancers using raman and fluorescence spectroscopies
US5991653A (en) * 1995-03-14 1999-11-23 Board Of Regents, The University Of Texas System Near-infrared raman spectroscopy for in vitro and in vivo detection of cervical precancers
US6258576B1 (en) 1996-06-19 2001-07-10 Board Of Regents, The University Of Texas System Diagnostic method and apparatus for cervical squamous intraepithelial lesions in vitro and in vivo using fluorescence spectroscopy
US5840017A (en) * 1995-08-03 1998-11-24 Asahi Kogaku Kogyo Kabushiki Kaisha Endoscope system
AU1130797A (en) * 1995-08-24 1997-03-19 Purdue Research Foundation Fluorescence lifetime-based imaging and spectroscopy in tissues and other random media
US7328059B2 (en) * 1996-08-23 2008-02-05 The Texas A & M University System Imaging of light scattering tissues with fluorescent contrast agents
EP0861044B1 (de) * 1995-09-26 2001-03-07 Karl Storz GmbH & Co. KG Vorrichtung zur photodynamischen diagnose
US5953477A (en) * 1995-11-20 1999-09-14 Visionex, Inc. Method and apparatus for improved fiber optic light management
US6174424B1 (en) 1995-11-20 2001-01-16 Cirrex Corp. Couplers for optical fibers
US5804389A (en) * 1995-12-29 1998-09-08 Phanos Technologies, Inc. Method for detecting abnormal epithelial cell shedding
US5647368A (en) * 1996-02-28 1997-07-15 Xillix Technologies Corp. Imaging system for detecting diseased tissue using native fluorsecence in the gastrointestinal and respiratory tract
JP3796635B2 (ja) * 1996-03-06 2006-07-12 富士写真フイルム株式会社 蛍光検出装置
US6571119B2 (en) 1996-03-06 2003-05-27 Fuji Photo Film Co., Ltd. Fluorescence detecting apparatus
US5928627A (en) * 1996-04-19 1999-07-27 The Dow Chemical Company Fluorescent chelates as visual tissue specific imaging agents
US5842995A (en) * 1996-06-28 1998-12-01 Board Of Regents, The Univerisity Of Texas System Spectroscopic probe for in vivo measurement of raman signals
US6293911B1 (en) * 1996-11-20 2001-09-25 Olympus Optical Co., Ltd. Fluorescent endoscope system enabling simultaneous normal light observation and fluorescence observation in infrared spectrum
US7179222B2 (en) * 1996-11-20 2007-02-20 Olympus Corporation Fluorescent endoscope system enabling simultaneous achievement of normal light observation based on reflected light and fluorescence observation based on light with wavelengths in infrared spectrum
JP3713347B2 (ja) * 1996-11-25 2005-11-09 オリンパス株式会社 蛍光内視鏡装置
US6119031A (en) 1996-11-21 2000-09-12 Boston Scientific Corporation Miniature spectrometer
CA2192036A1 (en) * 1996-12-04 1998-06-04 Harvey Lui Fluorescence scope system for dermatologic diagnosis
US7865230B1 (en) 1997-02-07 2011-01-04 Texas A&M University System Method and system for detecting sentinel lymph nodes
EP1011422B1 (de) * 1997-02-07 2004-11-10 The Texas A & M University System Abbildung von lichtstreuenden geweben mittels fluoreszierender kontrastmittel
JP3654325B2 (ja) * 1997-02-13 2005-06-02 富士写真フイルム株式会社 蛍光検出装置
WO1998037811A1 (en) 1997-02-28 1998-09-03 Electro-Optical Sciences, Inc. Systems and methods for the multispectral imaging and characterization of skin tissue
US6081612A (en) * 1997-02-28 2000-06-27 Electro Optical Sciences Inc. Systems and methods for the multispectral imaging and characterization of skin tissue
AU6604998A (en) 1997-03-13 1998-09-29 Biomax Technologies, Inc. Methods and apparatus for detecting the rejection of transplanted tissue
US6208783B1 (en) 1997-03-13 2001-03-27 Cirrex Corp. Optical filtering device
US6008889A (en) * 1997-04-16 1999-12-28 Zeng; Haishan Spectrometer system for diagnosis of skin disease
US6317624B1 (en) 1997-05-05 2001-11-13 The General Hospital Corporation Apparatus and method for demarcating tumors
US6280386B1 (en) * 1997-06-16 2001-08-28 The Research Foundation Of The City University Of New York Apparatus for enhancing the visibility of a luminous object inside tissue and methods for same
US6185443B1 (en) 1997-09-29 2001-02-06 Boston Scientific Corporation Visible display for an interventional device
US6422994B1 (en) * 1997-09-24 2002-07-23 Olympus Optical Co., Ltd. Fluorescent diagnostic system and method providing color discrimination enhancement
US6289236B1 (en) * 1997-10-10 2001-09-11 The General Hospital Corporation Methods and apparatus for distinguishing inflamed and tumorous bladder tissue
US6937885B1 (en) * 1997-10-30 2005-08-30 Hypermed, Inc. Multispectral/hyperspectral medical instrument
US6179777B1 (en) 1997-11-27 2001-01-30 Asahi Kogaku Kogyo Kabushiki Kaisha Fluorescent diagnosing apparatus including optical path switching member
US8974363B2 (en) * 1997-12-11 2015-03-10 Provectus Pharmatech, Inc. Topical medicaments and methods for photodynamic treatment of disease
US20030135122A1 (en) * 1997-12-12 2003-07-17 Spectrx, Inc. Multi-modal optical tissue diagnostic system
US6055451A (en) 1997-12-12 2000-04-25 Spectrx, Inc. Apparatus and method for determining tissue characteristics
DE19800312A1 (de) * 1998-01-07 1999-07-08 Wolf Gmbh Richard Diagnosegerät zur bildgebenden Aufnahme fluoreszierender biologischer Gewebebereiche
US6289229B1 (en) 1998-01-20 2001-09-11 Scimed Life Systems, Inc. Readable probe array for in vivo use
AU752829B2 (en) * 1998-01-26 2002-10-03 Brigham And Women's Hospital Fluorescence imaging endoscope
US6364829B1 (en) * 1999-01-26 2002-04-02 Newton Laboratories, Inc. Autofluorescence imaging system for endoscopy
US6129667A (en) * 1998-02-02 2000-10-10 General Electric Company Luminal diagnostics employing spectral analysis
US6174291B1 (en) 1998-03-09 2001-01-16 Spectrascience, Inc. Optical biopsy system and methods for tissue diagnosis
US6462770B1 (en) * 1998-04-20 2002-10-08 Xillix Technologies Corp. Imaging system with automatic gain control for reflectance and fluorescence endoscopy
US6447527B1 (en) * 1998-04-23 2002-09-10 Ronald J. Thompson Apparatus and methods for the penetration of tissue
US6371908B1 (en) * 1998-05-01 2002-04-16 Asahi Kogaku Kogyo Kabushiki Kaisha Video endoscopic apparatus for fluorescent diagnosis
US6592847B1 (en) * 1998-05-14 2003-07-15 The General Hospital Corporation Intramolecularly-quenched near infrared flourescent probes
GB9810471D0 (en) * 1998-05-16 1998-07-15 Helmet Hund Gmbh Toothbrush
US6110106A (en) * 1998-06-24 2000-08-29 Biomax Technologies, Inc. Endoscopes and methods relating to direct viewing of a target tissue
US6444970B1 (en) 1998-06-26 2002-09-03 Scimed Life Systems, Inc. Miniature low-noise photodiode system
US20090117199A1 (en) * 1998-08-06 2009-05-07 Scott Timothy C Method of treatment of cancer
US8557298B2 (en) * 1998-08-06 2013-10-15 Provectus Pharmatech, Inc. Medicaments for chemotherapeutic treatment of disease
US8024027B2 (en) 1998-09-03 2011-09-20 Hyperspectral Imaging, Inc. Infrared endoscopic balloon probes
AU5908699A (en) 1998-09-03 2000-03-27 Hypermed Imaging, Inc. Infrared endoscopic balloon probes
AU6139199A (en) * 1998-09-11 2000-04-03 Spectrx, Inc. Multi-modal optical tissue diagnostic system
US6256530B1 (en) 1998-09-15 2001-07-03 Denvu, L.L.C. Optical instrument and technique for cancer diagnosis using in-vivo fluorescence emission of test tissue
US6377842B1 (en) 1998-09-22 2002-04-23 Aurora Optics, Inc. Method for quantitative measurement of fluorescent and phosphorescent drugs within tissue utilizing a fiber optic probe
US6544370B1 (en) 1998-10-06 2003-04-08 Impulse Wear, Inc. Puff heat transfer
US6178346B1 (en) * 1998-10-23 2001-01-23 David C. Amundson Infrared endoscopic imaging in a liquid with suspended particles: method and apparatus
KR20010110420A (ko) * 1999-01-26 2001-12-13 추후제출 내시경 진단용 자가 형광 영상화 시스템
US8068897B1 (en) 1999-03-01 2011-11-29 Gazdzinski Robert F Endoscopic smart probe and method
US7914442B1 (en) 1999-03-01 2011-03-29 Gazdzinski Robert F Endoscopic smart probe and method
US10973397B2 (en) 1999-03-01 2021-04-13 West View Research, Llc Computerized information collection and processing apparatus
US8636648B2 (en) 1999-03-01 2014-01-28 West View Research, Llc Endoscopic smart probe
US6580935B1 (en) 1999-03-12 2003-06-17 Cirrex Corp. Method and system for stabilizing reflected light
JP3309276B2 (ja) * 1999-03-17 2002-07-29 エーカポット・パンナチェート 蛍光電子内視鏡システム
US20040147843A1 (en) * 1999-11-05 2004-07-29 Shabbir Bambot System and method for determining tissue characteristics
US6902527B1 (en) * 1999-05-18 2005-06-07 Olympus Corporation Endoscope system with charge multiplying imaging device and automatic gain control
US6205354B1 (en) 1999-06-18 2001-03-20 University Of Utah Method and apparatus for noninvasive measurement of carotenoids and related chemical substances in biological tissue
US6697666B1 (en) 1999-06-22 2004-02-24 Board Of Regents, The University Of Texas System Apparatus for the characterization of tissue of epithelial lined viscus
CA2383696C (en) * 1999-09-01 2009-05-26 Hamamatsu Photonics K.K. Weak light color imaging device
US7054002B1 (en) 1999-10-08 2006-05-30 The Texas A&M University System Characterization of luminescence in a scattering medium
US6652452B1 (en) 1999-10-25 2003-11-25 Advanced Medical Electronics Corporation Infrared endoscope with sensor array at the distal tip
DE60045146D1 (de) * 1999-11-02 2010-12-09 Fujifilm Corp Gerät zur Darstellung von Fluoreszenz
JP3983947B2 (ja) * 1999-11-16 2007-09-26 富士フイルム株式会社 蛍光画像表示方法および装置
EP1101438B1 (de) 1999-11-18 2006-10-18 Fuji Photo Film Co., Ltd. Verfahren und Vorrichtung zur Erzeugung von Fluoreszenzbildern
EP1239771B1 (de) * 1999-12-22 2004-10-06 Xillix Technologies Corp. Tragbares system zur ermittlung von hautanomalien
US6603552B1 (en) 1999-12-22 2003-08-05 Xillix Technologies Corp. Portable system for detecting skin abnormalities based on characteristic autofluorescence
US20020138008A1 (en) * 2000-01-13 2002-09-26 Kazuhiro Tsujita Method and apparatus for displaying fluorescence images and method and apparatus for acquiring endoscope images
JP4433347B2 (ja) * 2000-01-17 2010-03-17 富士フイルム株式会社 蛍光撮像装置
BR0108031B1 (pt) * 2000-01-29 2009-08-11 aparelho para a detecção e quantificação de inflamações de articulações e do tecido conectivo.
JP4265851B2 (ja) * 2000-02-07 2009-05-20 富士フイルム株式会社 蛍光撮像装置
US7039453B2 (en) * 2000-02-08 2006-05-02 Tarun Mullick Miniature ingestible capsule
JP2004500197A (ja) 2000-02-08 2004-01-08 コーネル　リサーチ　ファンデーション　インコーポレーテッド 光ファイバーを通じた蛍光分光用の多光子励起
US6766184B2 (en) 2000-03-28 2004-07-20 Board Of Regents, The University Of Texas System Methods and apparatus for diagnostic multispectral digital imaging
US6377841B1 (en) 2000-03-31 2002-04-23 Vanderbilt University Tumor demarcation using optical spectroscopy
US20040044287A1 (en) * 2000-03-31 2004-03-04 Wei-Chiang Lin Identification of human tissue using optical spectroscopy
US8888688B2 (en) 2000-04-03 2014-11-18 Intuitive Surgical Operations, Inc. Connector device for a controllable instrument
US20050085693A1 (en) * 2000-04-03 2005-04-21 Amir Belson Activated polymer articulated instruments and methods of insertion
US8517923B2 (en) * 2000-04-03 2013-08-27 Intuitive Surgical Operations, Inc. Apparatus and methods for facilitating treatment of tissue via improved delivery of energy based and non-energy based modalities
US6984203B2 (en) * 2000-04-03 2006-01-10 Neoguide Systems, Inc. Endoscope with adjacently positioned guiding apparatus
US6610007B2 (en) * 2000-04-03 2003-08-26 Neoguide Systems, Inc. Steerable segmented endoscope and method of insertion
US6858005B2 (en) * 2000-04-03 2005-02-22 Neo Guide Systems, Inc. Tendon-driven endoscope and methods of insertion
US6468203B2 (en) 2000-04-03 2002-10-22 Neoguide Systems, Inc. Steerable endoscope and improved method of insertion
DE60144202D1 (de) 2000-06-06 2011-04-21 Fujifilm Corp Fluorezentlicht Bilddarstellungsverfahren und Gerät dafür
DE60109989T2 (de) 2000-06-26 2006-02-23 Fuji Photo Film Co. Ltd., Minamiashigara Vorrichtung zur Aufnahme von Fluoreszenzbildern
EP1731087A3 (de) 2000-07-14 2008-08-06 Novadaq Technologies Inc. Kompaktes fluoreszenzendoskopisches Videosystem
US7068316B1 (en) * 2000-09-29 2006-06-27 Ess Technology, Inc. Selectable resolution image capture system
US20020107448A1 (en) * 2000-10-06 2002-08-08 Gandjbakhche Amir H. Probe using diffuse-reflectance spectroscopy
AU2001293592A1 (en) * 2000-10-06 2002-04-15 Peter R. Herman Multi-spectral fluorescence imaging and spectroscopy device
AU2002230842A1 (en) 2000-10-30 2002-05-15 The General Hospital Corporation Optical methods and systems for tissue analysis
DE60128138T2 (de) * 2000-11-02 2008-01-03 Cornell Research Foundation, Inc. In vivo multiphoton diagnostische detektion und bilddarstellung einer neurodegenerativen erkrankung
JP4520014B2 (ja) * 2000-11-10 2010-08-04 Ｈｏｙａ株式会社 電子内視鏡装置
US9295391B1 (en) 2000-11-10 2016-03-29 The General Hospital Corporation Spectrally encoded miniature endoscopic imaging probe
US6615063B1 (en) * 2000-11-27 2003-09-02 The General Hospital Corporation Fluorescence-mediated molecular tomography
US7383076B2 (en) * 2000-11-27 2008-06-03 The General Hospital Corporation Fluorescence-mediated molecular tomography
EP1210907A1 (de) * 2000-12-04 2002-06-05 Fuji Photo Film Co., Ltd. Vorrichtung zur Aufnahme von Fluoreszenzbildern
US6826424B1 (en) * 2000-12-19 2004-11-30 Haishan Zeng Methods and apparatus for fluorescence and reflectance imaging and spectroscopy and for contemporaneous measurements of electromagnetic radiation with multiple measuring devices
US20030044353A1 (en) * 2001-01-05 2003-03-06 Ralph Weissleder Activatable imaging probes
US6529769B2 (en) 2001-03-08 2003-03-04 Apti, Inc. Apparatus for performing hyperspectral endoscopy
CN100469308C (zh) * 2001-03-14 2009-03-18 吉温成象有限公司 检测活体内色度异常的可吞咽胶囊和系统
US6600947B2 (en) 2001-03-16 2003-07-29 Nymox Corporation Method of detecting amyloid-containing lesions by autofluorescence
DE10116859C2 (de) * 2001-04-04 2003-10-09 Wolf Gmbh Richard Vorrichtung zur bildgebenden Diagnose von Gewebe
US7123756B2 (en) * 2001-04-27 2006-10-17 Fuji Photo Film Co., Ltd. Method and apparatus for standardized fluorescence image generation
EP2333523B1 (de) * 2001-04-30 2020-04-08 The General Hospital Corporation Verfahren und vorrichtung zur verbesserung der bildklarheit und empfindlichkeit bei der optischen kohärenz-tomographie unter verwendung von dynamischer rückkopplung zur kontrolle der fokussierungseigenschaften und der kohärenzsteuerung
AT503309B1 (de) 2001-05-01 2011-08-15 Gen Hospital Corp Vorrichtung zur bestimmung von atherosklerotischem belag durch messung von optischen gewebeeigenschaften
EP1258220B1 (de) * 2001-05-16 2008-08-13 Olympus Corporation Endoskop mit Bildverarbeitungseinrichtung
US7172553B2 (en) 2001-05-16 2007-02-06 Olympus Corporation Endoscope system using normal light and fluorescence
JP2002345733A (ja) * 2001-05-29 2002-12-03 Fuji Photo Film Co Ltd 撮像装置
JP3862582B2 (ja) * 2001-06-29 2006-12-27 富士フイルムホールディングス株式会社 蛍光画像取得方法および装置並びにプログラム
US9113846B2 (en) 2001-07-26 2015-08-25 Given Imaging Ltd. In-vivo imaging device providing data compression
JP4316170B2 (ja) * 2001-09-05 2009-08-19 富士フイルム株式会社 画像データ作成方法および装置
JP4772235B2 (ja) * 2001-09-13 2011-09-14 オリンパス株式会社 内視鏡装置
US6756586B2 (en) 2001-10-15 2004-06-29 Vanderbilt University Methods and apparatus for analyzing biological samples by mass spectrometry
US6980299B1 (en) * 2001-10-16 2005-12-27 General Hospital Corporation Systems and methods for imaging a sample
KR100411631B1 (ko) * 2001-10-18 2003-12-18 주식회사 메디미르 형광 내시경 장치 및 그 장치를 이용한 진단부위 조상 방법
DE10153900B4 (de) 2001-11-02 2006-04-27 Richard Wolf Gmbh Vorrichtung zur bildgebenden Diagnose von Gewebe
US7738032B2 (en) * 2001-11-08 2010-06-15 Johnson & Johnson Consumer Companies, Inc. Apparatus for and method of taking and viewing images of the skin
US20040146290A1 (en) * 2001-11-08 2004-07-29 Nikiforos Kollias Method of taking images of the skin using blue light and the use thereof
US6922523B2 (en) * 2001-11-08 2005-07-26 Johnson & Johnson Consumer Companies, Inc. Method of promoting skin care products
US20030109787A1 (en) * 2001-12-12 2003-06-12 Michael Black Multiple laser diagnostics
US7039452B2 (en) 2002-12-19 2006-05-02 The University Of Utah Research Foundation Method and apparatus for Raman imaging of macular pigments
JP2005514144A (ja) * 2002-01-09 2005-05-19 ネオガイド システムズ， インコーポレイテッド 結腸の分光学的試験についての装置および方法
CN1764416A (zh) 2002-01-09 2006-04-26 新引导系统公司 用于内窥镜结肠切除术的设备和方法
ATE503982T1 (de) * 2002-01-11 2011-04-15 Gen Hospital Corp Vorrichtung zur oct bildaufnahme mit axialem linienfokus für verbesserte auflösung und tiefenschärfe
US20060241496A1 (en) * 2002-01-15 2006-10-26 Xillix Technologies Corp. Filter for use with imaging endoscopes
US6899675B2 (en) * 2002-01-15 2005-05-31 Xillix Technologies Corp. Fluorescence endoscopy video systems with no moving parts in the camera
US7355716B2 (en) 2002-01-24 2008-04-08 The General Hospital Corporation Apparatus and method for ranging and noise reduction of low coherence interferometry LCI and optical coherence tomography OCT signals by parallel detection of spectral bands
EP1485011B1 (de) * 2002-03-12 2013-02-13 Beth Israel Deaconess Medical Center Medizinische bildgebungssysteme
US8620410B2 (en) * 2002-03-12 2013-12-31 Beth Israel Deaconess Medical Center Multi-channel medical imaging system
US9155544B2 (en) * 2002-03-20 2015-10-13 P Tech, Llc Robotic systems and methods
US8131332B2 (en) * 2002-04-04 2012-03-06 Veralight, Inc. Determination of a measure of a glycation end-product or disease state using tissue fluorescence of various sites
CN1474175B (zh) * 2002-04-15 2010-05-26 黄鹰 超精细光谱成像仪或系统
US20110201924A1 (en) * 2002-04-30 2011-08-18 The General Hospital Corporation Method and Apparatus for Improving Image Clarity and Sensitivity in Optical Tomography Using Dynamic Feedback to Control Focal Properties and Coherence Gating
EP2410315B1 (de) 2002-06-04 2020-04-01 Visen Medical, Inc. Bildgebungsdatenträger mit willkürlichen Geometrien bei Kontakt- und kontaktloser Tomographie
DE10362402B3 (de) 2002-08-28 2022-03-03 Carl Zeiss Meditec Ag Mikroskopiesystem und Mikroskopieverfahren
US20060106317A1 (en) 2002-09-16 2006-05-18 Joule Microsystems Canada Inc. Optical system and use thereof for detecting patterns in biological tissue
DE10252313B9 (de) * 2002-11-11 2006-10-19 Carl Zeiss Untersuchungssystem zur gleichzeitigen direkten Sichtbarmachung einer Fluoreszenzmarkierung und eines die Fluoreszenzmarkierung umgebenden Gewebebereichs und Untersuchungsverfahren dafür
US7567349B2 (en) * 2003-03-31 2009-07-28 The General Hospital Corporation Speckle reduction in optical coherence tomography by path length encoded angular compounding
US8054468B2 (en) 2003-01-24 2011-11-08 The General Hospital Corporation Apparatus and method for ranging and noise reduction of low coherence interferometry LCI and optical coherence tomography OCT signals by parallel detection of spectral bands
JP2006516739A (ja) * 2003-01-24 2006-07-06 ザ・ジェネラル・ホスピタル・コーポレイション 低コヒーレンス干渉計を用いて組織を識別するためのシステムおよび方法
EP1593095B1 (de) 2003-02-05 2019-04-17 The General Hospital Corporation Verfahren und vorrichtung zur bilderzeugung mittels optischer freiraumtomographie für diffuse medien
US7613335B2 (en) * 2003-02-12 2009-11-03 The University Of Iowa Research Foundation Methods and devices useful for analyzing color medical images
US20040254479A1 (en) * 2003-02-20 2004-12-16 John Fralick Bio-photonic feedback control software and database
US20040186813A1 (en) * 2003-02-26 2004-09-23 Tedesco Daniel E. Image analysis method and apparatus in a network that is structured with multiple layers and differentially weighted neurons
US8882657B2 (en) 2003-03-07 2014-11-11 Intuitive Surgical Operations, Inc. Instrument having radio frequency identification systems and methods for use
JP3898661B2 (ja) * 2003-03-18 2007-03-28 株式会社ミワテック 蛍光標識用センサー装置。
US20070049830A1 (en) * 2003-03-18 2007-03-01 Hendriks Robert F M Analysis of a composition with monitoring
US20040210107A1 (en) * 2003-03-31 2004-10-21 Pentax Corporation Endoscope system for fluorescent observation
US20050245789A1 (en) 2003-04-01 2005-11-03 Boston Scientific Scimed, Inc. Fluid manifold for endoscope system
US7578786B2 (en) 2003-04-01 2009-08-25 Boston Scientific Scimed, Inc. Video endoscope
US7591783B2 (en) 2003-04-01 2009-09-22 Boston Scientific Scimed, Inc. Articulation joint for video endoscope
US20040199052A1 (en) 2003-04-01 2004-10-07 Scimed Life Systems, Inc. Endoscopic imaging system
US8118732B2 (en) 2003-04-01 2012-02-21 Boston Scientific Scimed, Inc. Force feedback control system for video endoscope
US20040202356A1 (en) * 2003-04-10 2004-10-14 Stookey George K. Optical detection of dental caries
US20040225222A1 (en) * 2003-05-08 2004-11-11 Haishan Zeng Real-time contemporaneous multimodal imaging and spectroscopy uses thereof
US20040254478A1 (en) * 2003-05-22 2004-12-16 De Josselin De Jong Elbert Fluorescence filter for tissue examination and imaging
US7697975B2 (en) * 2003-06-03 2010-04-13 British Colombia Cancer Agency Methods and apparatus for fluorescence imaging using multiple excitation-emission pairs and simultaneous multi-channel image detection
KR101546024B1 (ko) 2003-06-06 2015-08-20 더 제너럴 하스피탈 코포레이션 파장 동조 소스용 방법 및 장치
US7599732B2 (en) * 2003-06-20 2009-10-06 The Texas A&M University System Method and system for near-infrared fluorescence contrast-enhanced imaging with area illumination and area detection
WO2005057244A2 (en) * 2003-08-19 2005-06-23 Cornell Research Foundation, Inc. Optical fiber delivery and collection system for biological applications
FR2859279B1 (fr) * 2003-09-03 2005-11-25 Jobin Yvon Sas Dispositif et procede de mesure spectroscopique avec un dispositif d'imagerie comprenant une matrice de photodetecteurs
WO2005034747A1 (en) * 2003-09-15 2005-04-21 Beth Israel Deaconess Medical Center Medical imaging systems
US7321791B2 (en) * 2003-09-23 2008-01-22 Cambridge Research And Instrumentation, Inc. Spectral imaging of deep tissue
US8634607B2 (en) 2003-09-23 2014-01-21 Cambridge Research & Instrumentation, Inc. Spectral imaging of biological samples
KR101384553B1 (ko) 2003-10-27 2014-04-11 더 제너럴 하스피탈 코포레이션 주파수 영역 간섭법을 이용하여 광 영상화를 수행하는 방법 및 장치
WO2005051182A1 (de) * 2003-11-19 2005-06-09 Richard Wolf Gmbh Vorrichtung zur bildgebenden diagnose von gewebe
WO2005054780A1 (en) * 2003-11-28 2005-06-16 The General Hospital Corporation Method and apparatus for three-dimensional spectrally encoded imaging
DE10357184A1 (de) * 2003-12-08 2005-07-07 Siemens Ag Verfahren zur fusionierten Bilddarstellung
US20050278184A1 (en) * 2004-06-10 2005-12-15 John Fralick Bio-photonic feedback control software and database
US7998060B2 (en) 2004-04-19 2011-08-16 The Invention Science Fund I, Llc Lumen-traveling delivery device
US8353896B2 (en) 2004-04-19 2013-01-15 The Invention Science Fund I, Llc Controllable release nasal system
US8092549B2 (en) 2004-09-24 2012-01-10 The Invention Science Fund I, Llc Ciliated stent-like-system
US7857767B2 (en) * 2004-04-19 2010-12-28 Invention Science Fund I, Llc Lumen-traveling device
US8337482B2 (en) 2004-04-19 2012-12-25 The Invention Science Fund I, Llc System for perfusion management
US8019413B2 (en) 2007-03-19 2011-09-13 The Invention Science Fund I, Llc Lumen-traveling biological interface device and method of use
US9011329B2 (en) 2004-04-19 2015-04-21 Searete Llc Lumenally-active device
US8361013B2 (en) 2004-04-19 2013-01-29 The Invention Science Fund I, Llc Telescoping perfusion management system
US9801527B2 (en) 2004-04-19 2017-10-31 Gearbox, Llc Lumen-traveling biological interface device
EP1754016B1 (de) 2004-05-29 2016-05-18 The General Hospital Corporation Prozess, system und softwareanordnung für eine kompensation der chromatischen dispersion unter verwendung reflektierender schichten in der bildgebenden optischen kohärenztopographie (oct)
US7270543B2 (en) 2004-06-29 2007-09-18 Therametric Technologies, Inc. Handpiece for caries detection
US9968290B2 (en) * 2004-06-30 2018-05-15 Given Imaging Ltd. Apparatus and methods for capsule endoscopy of the esophagus
US7447408B2 (en) 2004-07-02 2008-11-04 The General Hospital Corproation Imaging system and related techniques
KR101332222B1 (ko) 2004-08-06 2013-11-22 더 제너럴 하스피탈 코포레이션 광간섭 단층촬영법을 이용해서 샘플 내에서 적어도 하나의 위치를 결정하는 방법, 시스템 및 그 방법을 구현하기 위한 소프트웨어가 저장되어 컴퓨터로 판독 가능한 매체
EP2272421A1 (de) * 2004-08-24 2011-01-12 The General Hospital Corporation Verfahren und Vorrichtung zur Abbildung von Gefäßsegmenten
JP5334415B2 (ja) * 2004-08-24 2013-11-06 ザ ジェネラル ホスピタル コーポレイション 試料の機械的歪み及び弾性的性質を測定するプロセス、システム及びソフトウェア
JP4384626B2 (ja) * 2004-09-02 2009-12-16 オリンパス株式会社 内視鏡装置
KR100895160B1 (ko) * 2004-08-30 2009-05-04 올림푸스 가부시키가이샤 내시경 장치
JP4009626B2 (ja) * 2004-08-30 2007-11-21 オリンパス株式会社 内視鏡用映像信号処理装置
US7365859B2 (en) * 2004-09-10 2008-04-29 The General Hospital Corporation System and method for optical coherence imaging
US7366376B2 (en) * 2004-09-29 2008-04-29 The General Hospital Corporation System and method for optical coherence imaging
US8083671B2 (en) 2004-09-30 2011-12-27 Boston Scientific Scimed, Inc. Fluid delivery system for use with an endoscope
US8357148B2 (en) 2004-09-30 2013-01-22 Boston Scientific Scimed, Inc. Multi-functional endoscopic system for use in electrosurgical applications
US7479106B2 (en) 2004-09-30 2009-01-20 Boston Scientific Scimed, Inc. Automated control of irrigation and aspiration in a single-use endoscope
US7241263B2 (en) 2004-09-30 2007-07-10 Scimed Life Systems, Inc. Selectively rotatable shaft coupler
US8353860B2 (en) 2004-09-30 2013-01-15 Boston Scientific Scimed, Inc. Device for obstruction removal with specific tip structure
WO2006039522A2 (en) 2004-09-30 2006-04-13 Boston Scientific Scimed, Inc. Adapter for use with digital imaging medical device
JP5175101B2 (ja) * 2004-10-29 2013-04-03 ザ ジェネラル ホスピタル コーポレイション 偏光感応性光コヒーレンストモグラフィを用いて偏光非解消の偏光パラメータを測定するジョーンズ行列に基づく解析を行うシステム及び方法
US8026942B2 (en) 2004-10-29 2011-09-27 Johnson & Johnson Consumer Companies, Inc. Skin imaging system with probe
EP1807722B1 (de) * 2004-11-02 2022-08-10 The General Hospital Corporation Faseroptische drehvorrichtung, optisches system zur abbildung einer probe
US7365839B2 (en) * 2004-11-03 2008-04-29 Nu Skin International, Inc. Process and compositions for synthetic calibration of bio-photonic scanners
US7763058B2 (en) * 2004-11-20 2010-07-27 Dick Sterenborg Device and method for photodynamic therapy of the nasopharyngeal cavity
EP2278266A3 (de) * 2004-11-24 2011-06-29 The General Hospital Corporation Interferometer mit gemeinsamem Pfad für endoskopische optische Kohärenztomographie
US8922781B2 (en) * 2004-11-29 2014-12-30 The General Hospital Corporation Arrangements, devices, endoscopes, catheters and methods for performing optical imaging by simultaneously illuminating and detecting multiple points on a sample
WO2006063246A1 (en) 2004-12-08 2006-06-15 The General Hospital Corporation System and method for normalized fluorescence or bioluminescence imaging
EP2237189B1 (de) 2005-01-27 2018-08-01 Cambridge Research & Instrumentation, Inc. Klassifizierung von Bildmerkmalen
DE102005013043A1 (de) * 2005-03-18 2006-09-28 Siemens Ag Mobiler Fluoreszenz-Scanner für molekulare Signaturen
US20060217594A1 (en) * 2005-03-24 2006-09-28 Ferguson Gary W Endoscopy device with removable tip
IL174531A0 (en) * 2005-04-06 2006-08-20 Given Imaging Ltd System and method for performing capsule endoscopy diagnosis in remote sites
US20060235457A1 (en) * 2005-04-15 2006-10-19 Amir Belson Instruments having a rigidizable external working channel
JP2008538612A (ja) * 2005-04-22 2008-10-30 ザ ジェネラル ホスピタル コーポレイション スペクトルドメイン偏光感受型光コヒーレンストモグラフィを提供することの可能な構成、システム、及び方法
KR101410867B1 (ko) 2005-04-28 2014-06-23 더 제너럴 하스피탈 코포레이션 광간섭 정렬 기술로 해부학적 구조와 연계된 정보를평가하는 시스템, 공정 및 소프트웨어 배열
US8097003B2 (en) 2005-05-13 2012-01-17 Boston Scientific Scimed, Inc. Endoscopic apparatus with integrated variceal ligation device
US20070009935A1 (en) * 2005-05-13 2007-01-11 The General Hospital Corporation Arrangements, systems and methods capable of providing spectral-domain optical coherence reflectometry for a sensitive detection of chemical and biological sample
US7846107B2 (en) 2005-05-13 2010-12-07 Boston Scientific Scimed, Inc. Endoscopic apparatus with integrated multiple biopsy device
US20060293556A1 (en) * 2005-05-16 2006-12-28 Garner David M Endoscope with remote control module or camera
JP2008542758A (ja) * 2005-05-31 2008-11-27 ザ ジェネラル ホスピタル コーポレイション スペクトルコード化ヘテロダイン干渉法を画像化に使用可能なシステム、方法、及び装置
EP1889037A2 (de) * 2005-06-01 2008-02-20 The General Hospital Corporation Vorrichtung, verfahren und system zur abbildung phasenaufgelöster optischer frequenzdomänen
JP4733433B2 (ja) * 2005-06-03 2011-07-27 株式会社日立ソリューションズ ビーズアレイ用蛍光読取装置及びビーズアレイ用蛍光読取方法
JP5191090B2 (ja) * 2005-07-15 2013-04-24 オリンパスメディカルシステムズ株式会社 内視鏡装置
DE602006017558D1 (de) * 2005-08-09 2010-11-25 Gen Hospital Corp Gerät und verfahren zur durchführung von polarisationsbasierter quadraturdemodulation bei optischer kohärenztomographie
WO2007022220A2 (en) * 2005-08-16 2007-02-22 The General Hospital Corporation Arrangements and methods for imaging in vessels
US8451327B2 (en) * 2005-08-18 2013-05-28 Hoya Corporation Electronic endoscope, endoscope light unit, endoscope processor, and electronic endoscope system
JP4681981B2 (ja) * 2005-08-18 2011-05-11 Ｈｏｙａ株式会社 電子内視鏡装置
US8052597B2 (en) 2005-08-30 2011-11-08 Boston Scientific Scimed, Inc. Method for forming an endoscope articulation joint
JP5114024B2 (ja) 2005-08-31 2013-01-09 オリンパス株式会社 光イメージング装置
US20070122344A1 (en) 2005-09-02 2007-05-31 University Of Rochester Medical Center Office Of Technology Transfer Intraoperative determination of nerve location
US20070135803A1 (en) * 2005-09-14 2007-06-14 Amir Belson Methods and apparatus for performing transluminal and other procedures
EP1937137B1 (de) 2005-09-29 2022-06-15 General Hospital Corporation Verfahren und gerät zur optischen darstellung via spektrale codierung
KR20080064155A (ko) 2005-10-14 2008-07-08 어플라이드 리써치 어쏘시에이츠 뉴질랜드 리미티드 표면 특징을 모니터링하는 방법 및 장치
EP1945094B1 (de) * 2005-10-14 2018-09-05 The General Hospital Corporation Spektral- und frequenz-kodierte fluoreszenz-darstellung
JP2007111357A (ja) * 2005-10-21 2007-05-10 Olympus Medical Systems Corp 生体撮像装置及び生体観測システム
US7596253B2 (en) * 2005-10-31 2009-09-29 Carestream Health, Inc. Method and apparatus for detection of caries
US20100020164A1 (en) * 2005-11-04 2010-01-28 Ronald Perrault Surface Analysis Method and System
EP1951115A4 (de) * 2005-11-11 2013-10-30 Randall L Barbour Funktionale darstellung von autoregulation
US20070161857A1 (en) 2005-11-22 2007-07-12 Neoguide Systems, Inc. Method of determining the shape of a bendable instrument
JP2009517608A (ja) * 2005-11-23 2009-04-30 ネオガイド システムズ， インコーポレイテッド 操舵可能な装置用の非金属マルチストランド制御ケーブル
JP5680826B2 (ja) 2006-01-10 2015-03-04 ザ ジェネラル ホスピタル コーポレイション １以上のスペクトルを符号化する内視鏡技術によるデータ生成システム
US8145018B2 (en) 2006-01-19 2012-03-27 The General Hospital Corporation Apparatus for obtaining information for a structure using spectrally-encoded endoscopy techniques and methods for producing one or more optical arrangements
US9087368B2 (en) 2006-01-19 2015-07-21 The General Hospital Corporation Methods and systems for optical imaging or epithelial luminal organs by beam scanning thereof
US7967759B2 (en) 2006-01-19 2011-06-28 Boston Scientific Scimed, Inc. Endoscopic system with integrated patient respiratory status indicator
US20070223006A1 (en) * 2006-01-19 2007-09-27 The General Hospital Corporation Systems and methods for performing rapid fluorescence lifetime, excitation and emission spectral measurements
EP1973467B1 (de) * 2006-01-20 2013-10-16 The General Hospital Corporation Systeme und Verfahren zur Bereitstellung von Speckle-Reduktion über eine Wellenfront -Modulation zur optischen Kohärenzentomographie
US20070171430A1 (en) * 2006-01-20 2007-07-26 The General Hospital Corporation Systems and methods for providing mirror tunnel micropscopy
US20070171433A1 (en) * 2006-01-20 2007-07-26 The General Hospital Corporation Systems and processes for providing endogenous molecular imaging with mid-infrared light
EP2659852A3 (de) * 2006-02-01 2014-01-15 The General Hospital Corporation Vorrichtung zur Anwendung mehrerer elektromagnetischer Strahlungen auf einer Probe
JP2009537024A (ja) * 2006-02-01 2009-10-22 ザ ジェネラル ホスピタル コーポレイション 少なくとも一つのファイバの少なくとも二つの部位の少なくとも一つを制御する装置
US10426548B2 (en) * 2006-02-01 2019-10-01 The General Hosppital Corporation Methods and systems for providing electromagnetic radiation to at least one portion of a sample using conformal laser therapy procedures
WO2007106624A2 (en) 2006-02-07 2007-09-20 Novadaq Technologies Inc. Near infrared imaging
WO2007092911A2 (en) 2006-02-08 2007-08-16 The General Hospital Corporation Methods, arrangements and systems for obtaining information associated with an anatomical sample using optical microscopy
US20070224694A1 (en) * 2006-02-10 2007-09-27 Puchalski Daniel M Method and system for hyperspectral detection of animal diseases
WO2007101026A2 (en) * 2006-02-24 2007-09-07 The General Hospital Corporation Methods and systems for performing angle-resolved fourier-domain optical coherence tomography
JP4818753B2 (ja) * 2006-02-28 2011-11-16 オリンパス株式会社 内視鏡システム
US20070208400A1 (en) * 2006-03-01 2007-09-06 The General Hospital Corporation System and method for providing cell specific laser therapy of atherosclerotic plaques by targeting light absorbers in macrophages
WO2007109540A2 (en) * 2006-03-17 2007-09-27 The General Hospital Corporation Arrangement, method and computer-accessible medium for identifying characteristics of at least a portion of a blood vessel contained within a tissue using spectral domain low coherence interferometry
US8888684B2 (en) 2006-03-27 2014-11-18 Boston Scientific Scimed, Inc. Medical devices with local drug delivery capabilities
US7742173B2 (en) * 2006-04-05 2010-06-22 The General Hospital Corporation Methods, arrangements and systems for polarization-sensitive optical frequency domain imaging of a sample
US20080058786A1 (en) * 2006-04-12 2008-03-06 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Autofluorescent imaging and target ablation
US9220917B2 (en) 2006-04-12 2015-12-29 The Invention Science Fund I, Llc Systems for autofluorescent imaging and target ablation
US20120035438A1 (en) 2006-04-12 2012-02-09 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Path selection by a lumen traveling device in a body tub tree based on previous path
US8202265B2 (en) 2006-04-20 2012-06-19 Boston Scientific Scimed, Inc. Multiple lumen assembly for use in endoscopes or other medical devices
US7955255B2 (en) 2006-04-20 2011-06-07 Boston Scientific Scimed, Inc. Imaging assembly with transparent distal cap
WO2007133961A2 (en) 2006-05-10 2007-11-22 The General Hospital Corporation Processes, arrangements and systems for providing frequency domain imaging of a sample
WO2007133964A2 (en) * 2006-05-12 2007-11-22 The General Hospital Corporation Processes, arrangements and systems for providing a fiber layer thickness map based on optical coherence tomography images
US8140141B2 (en) * 2006-05-17 2012-03-20 University Of Utah Research Foundation Devices and methods for fluorescent inspection and/or removal of material in a sample
WO2007137208A2 (en) 2006-05-19 2007-11-29 Neoguide Systems, Inc. Methods and apparatus for displaying three-dimensional orientation of a steerable distal tip of an endoscope
JP2008005984A (ja) * 2006-06-28 2008-01-17 Univ Of Tokushima 青紫色レーザー光が誘導の自家蛍光を指標に用いる粘膜炎の定量的評価方法とその装置
US8078265B2 (en) 2006-07-11 2011-12-13 The General Hospital Corporation Systems and methods for generating fluorescent light images
US8408269B2 (en) 2006-07-28 2013-04-02 Novadaq Technologies, Inc. System and method for deposition and removal of an optical element on an endoscope objective
WO2008016927A2 (en) * 2006-08-01 2008-02-07 The General Hospital Corporation Systems and methods for receiving and/or analyzing information associated with electro-magnetic radiation
FR2904927B1 (fr) * 2006-08-17 2018-05-18 Mauna Kea Technologies Utilisation d'un systeme d'imagerie par fluorescence confocale fibre in vivo in situ, systeme et procede d'imagerie par fluorescence confocale fibres in vivo in situ
EP2054712B1 (de) * 2006-08-25 2015-10-07 The General Hospital Corporation Vorrichtungen und verfahren zur verstärkung einer optischen kohärenztomographie-abbildung mithilfe volumetrischer filterungsverfahren
CA2662893A1 (en) * 2006-09-06 2008-03-13 University Health Network Fluorescence quantification and image acquisition in highly turbid media
US20080161744A1 (en) 2006-09-07 2008-07-03 University Of Rochester Medical Center Pre-And Intra-Operative Localization of Penile Sentinel Nodes
EP2077753B1 (de) * 2006-09-12 2012-12-19 The General Hospital Corporation Vorrichtung, sonde und verfahren zur tiefenbeurteilung bei einer anatomischen struktur
US9079762B2 (en) 2006-09-22 2015-07-14 Ethicon Endo-Surgery, Inc. Micro-electromechanical device
WO2008039968A2 (en) * 2006-09-28 2008-04-03 The Research Foundation Of State University Of New York Apparatus, system, kit and method for heart mapping
WO2008049118A2 (en) 2006-10-19 2008-04-24 The General Hospital Corporation Apparatus and method for obtaining and providing imaging information associated with at least one portion of a sample and effecting such portion(s)
US7561317B2 (en) * 2006-11-03 2009-07-14 Ethicon Endo-Surgery, Inc. Resonant Fourier scanning
US20080146898A1 (en) * 2006-12-19 2008-06-19 Ethicon Endo-Surgery, Inc. Spectral windows for surgical treatment through intervening fluids
US20080151343A1 (en) * 2006-12-22 2008-06-26 Ethicon Endo-Surgery, Inc. Apparatus including a scanned beam imager having an optical dome
US7713265B2 (en) * 2006-12-22 2010-05-11 Ethicon Endo-Surgery, Inc. Apparatus and method for medically treating a tattoo
US8498695B2 (en) 2006-12-22 2013-07-30 Novadaq Technologies Inc. Imaging system with a single color image sensor for simultaneous fluorescence and color video endoscopy
US8360771B2 (en) 2006-12-28 2013-01-29 Therametric Technologies, Inc. Handpiece for detection of dental demineralization
US8801606B2 (en) 2007-01-09 2014-08-12 Ethicon Endo-Surgery, Inc. Method of in vivo monitoring using an imaging system including scanned beam imaging unit
US8273015B2 (en) * 2007-01-09 2012-09-25 Ethicon Endo-Surgery, Inc. Methods for imaging the anatomy with an anatomically secured scanner assembly
JP5074044B2 (ja) * 2007-01-18 2012-11-14 オリンパス株式会社 蛍光観察装置および蛍光観察装置の作動方法
US7589316B2 (en) * 2007-01-18 2009-09-15 Ethicon Endo-Surgery, Inc. Scanning beam imaging with adjustable detector sensitivity or gain
US20080206804A1 (en) * 2007-01-19 2008-08-28 The General Hospital Corporation Arrangements and methods for multidimensional multiplexed luminescence imaging and diagnosis
EP2102583A2 (de) 2007-01-19 2009-09-23 The General Hospital Corporation Vorrichtung und verfahren zur steuerung der entfernungsmessungstiefe bei der bildgebung im optischen frequenzbereich
EP2662674A3 (de) * 2007-01-19 2014-06-25 The General Hospital Corporation Drehscheibenreflexion zur schnellen Wellenlängendurchstimmung von dispergiertem Breitbandlicht
US20080177140A1 (en) * 2007-01-23 2008-07-24 Xillix Technologies Corp. Cameras for fluorescence and reflectance imaging
US7655004B2 (en) 2007-02-15 2010-02-02 Ethicon Endo-Surgery, Inc. Electroporation ablation apparatus, system, and method
US8216214B2 (en) 2007-03-12 2012-07-10 Ethicon Endo-Surgery, Inc. Power modulation of a scanning beam for imaging, therapy, and/or diagnosis
US20080226029A1 (en) * 2007-03-12 2008-09-18 Weir Michael P Medical device including scanned beam unit for imaging and therapy
WO2008115965A1 (en) * 2007-03-19 2008-09-25 The General Hospital Corporation Apparatus and method for providing a noninvasive diagnosis of internal bleeding
US20080234586A1 (en) * 2007-03-19 2008-09-25 The General Hospital Corporation System and method for providing noninvasive diagnosis of compartment syndrome using exemplary laser speckle imaging procedure
JP2008229024A (ja) * 2007-03-20 2008-10-02 Olympus Corp 蛍光観察装置
JP5436757B2 (ja) * 2007-03-20 2014-03-05 オリンパス株式会社 蛍光観察装置
US9176319B2 (en) * 2007-03-23 2015-11-03 The General Hospital Corporation Methods, arrangements and apparatus for utilizing a wavelength-swept laser using angular scanning and dispersion procedures
US10534129B2 (en) * 2007-03-30 2020-01-14 The General Hospital Corporation System and method providing intracoronary laser speckle imaging for the detection of vulnerable plaque
WO2008122033A1 (en) * 2007-04-02 2008-10-09 Wilson-Cook Medical, Inc. Endoscopic apparatus having an outer rail
US8626271B2 (en) 2007-04-13 2014-01-07 Ethicon Endo-Surgery, Inc. System and method using fluorescence to examine within a patient's anatomy
US7995045B2 (en) 2007-04-13 2011-08-09 Ethicon Endo-Surgery, Inc. Combined SBI and conventional image processor
US8045177B2 (en) * 2007-04-17 2011-10-25 The General Hospital Corporation Apparatus and methods for measuring vibrations using spectrally-encoded endoscopy
US8115919B2 (en) * 2007-05-04 2012-02-14 The General Hospital Corporation Methods, arrangements and systems for obtaining information associated with a sample using optical microscopy
US8160678B2 (en) 2007-06-18 2012-04-17 Ethicon Endo-Surgery, Inc. Methods and devices for repairing damaged or diseased tissue using a scanning beam assembly
US7558455B2 (en) * 2007-06-29 2009-07-07 Ethicon Endo-Surgery, Inc Receiver aperture broadening for scanned beam imaging
US7982776B2 (en) * 2007-07-13 2011-07-19 Ethicon Endo-Surgery, Inc. SBI motion artifact removal apparatus and method
US20090021818A1 (en) * 2007-07-20 2009-01-22 Ethicon Endo-Surgery, Inc. Medical scanning assembly with variable image capture and display
JP5917803B2 (ja) * 2007-07-31 2016-05-18 ザ ジェネラル ホスピタル コーポレイション 高速ドップラー光周波数領域撮像法のためのビーム走査パターンを放射するシステムおよび方法
US9125552B2 (en) * 2007-07-31 2015-09-08 Ethicon Endo-Surgery, Inc. Optical scanning module and means for attaching the module to medical instruments for introducing the module into the anatomy
US7983739B2 (en) 2007-08-27 2011-07-19 Ethicon Endo-Surgery, Inc. Position tracking and control for a scanning assembly
US7925333B2 (en) 2007-08-28 2011-04-12 Ethicon Endo-Surgery, Inc. Medical device including scanned beam unit with operational control features
US8040608B2 (en) * 2007-08-31 2011-10-18 The General Hospital Corporation System and method for self-interference fluorescence microscopy, and computer-accessible medium associated therewith
US20090073439A1 (en) * 2007-09-15 2009-03-19 The General Hospital Corporation Apparatus, computer-accessible medium and method for measuring chemical and/or molecular compositions of coronary atherosclerotic plaques in anatomical structures
US9220398B2 (en) 2007-10-11 2015-12-29 Intuitive Surgical Operations, Inc. System for managing Bowden cables in articulating instruments
WO2009049296A2 (en) * 2007-10-12 2009-04-16 The General Hospital Corporation Systems and processes for optical imaging of luminal anatomic structures
WO2009059034A1 (en) * 2007-10-30 2009-05-07 The General Hospital Corporation System and method for cladding mode detection
WO2009060460A2 (en) * 2007-11-09 2009-05-14 Given Imaging Ltd. Apparatus and methods for capsule endoscopy of the esophagus
US20090225324A1 (en) * 2008-01-17 2009-09-10 The General Hospital Corporation Apparatus for providing endoscopic high-speed optical coherence tomography
EP2732826B1 (de) 2008-01-18 2017-11-08 Visen Medical, Inc. Fluoreszierende Bildgebungsmittel
US20090192390A1 (en) * 2008-01-24 2009-07-30 Lifeguard Surgical Systems Common bile duct surgical imaging system
US9072445B2 (en) * 2008-01-24 2015-07-07 Lifeguard Surgical Systems Inc. Common bile duct surgical imaging system
US8406860B2 (en) 2008-01-25 2013-03-26 Novadaq Technologies Inc. Method for evaluating blush in myocardial tissue
US11123047B2 (en) 2008-01-28 2021-09-21 The General Hospital Corporation Hybrid systems and methods for multi-modal acquisition of intravascular imaging data and counteracting the effects of signal absorption in blood
US9332942B2 (en) * 2008-01-28 2016-05-10 The General Hospital Corporation Systems, processes and computer-accessible medium for providing hybrid flourescence and optical coherence tomography imaging
KR101707924B1 (ko) 2008-02-06 2017-02-17 인튜어티브 서지컬 오퍼레이션즈 인코포레이티드 제동 능력을 가지고 있는 체절식 기구
US8182418B2 (en) * 2008-02-25 2012-05-22 Intuitive Surgical Operations, Inc. Systems and methods for articulating an elongate body
CN102036599B (zh) 2008-03-18 2013-06-19 诺瓦达克技术公司 用于组合的全色反射和近红外成像的成像系统
US8050520B2 (en) * 2008-03-27 2011-11-01 Ethicon Endo-Surgery, Inc. Method for creating a pixel image from sampled data of a scanned beam imager
US10219742B2 (en) 2008-04-14 2019-03-05 Novadaq Technologies ULC Locating and analyzing perforator flaps for plastic and reconstructive surgery
JP4987790B2 (ja) * 2008-04-15 2012-07-25 オリンパスメディカルシステムズ株式会社 撮像装置
US8332014B2 (en) * 2008-04-25 2012-12-11 Ethicon Endo-Surgery, Inc. Scanned beam device and method using same which measures the reflectance of patient tissue
US8810631B2 (en) * 2008-04-26 2014-08-19 Intuitive Surgical Operations, Inc. Augmented stereoscopic visualization for a surgical robot using a captured visible image combined with a fluorescence image and a captured visible image
EP3372250B1 (de) 2008-05-02 2019-12-25 Novadaq Technologies ULC Verfahren zur herstellung und verwendung substanzbeladener erythrozyten zur beobachtung und behandlung von mikrovaskulärer hämodynamik
WO2009137701A2 (en) 2008-05-07 2009-11-12 The General Hospital Corporation System, method and computer-accessible medium for tracking vessel motion during three-dimensional coronary artery microscopy
US8956591B2 (en) * 2008-05-15 2015-02-17 Osaka Prefectural Hospital Organization Method for detecting cancer using ICG fluorescence method
ES2715633T3 (es) 2008-05-20 2019-06-05 Univ Health Network Dispositivo y método para formación de imágenes y supervisión por fluorescencia
JP5110702B2 (ja) * 2008-05-22 2012-12-26 富士フイルム株式会社 蛍光画像取得装置
US8861910B2 (en) * 2008-06-20 2014-10-14 The General Hospital Corporation Fused fiber optic coupler arrangement and method for use thereof
US20100010294A1 (en) * 2008-07-10 2010-01-14 Ethicon Endo-Surgery, Inc. Temporarily positionable medical devices
EP2309923B1 (de) 2008-07-14 2020-11-25 The General Hospital Corporation Vorrichtung und verfahren für eine farbendoskopie
US8888792B2 (en) 2008-07-14 2014-11-18 Ethicon Endo-Surgery, Inc. Tissue apposition clip application devices and methods
US8939966B2 (en) * 2008-08-21 2015-01-27 University Of Florida Research Foundation, Inc. Differential laser-induced perturbation (DLIP) for bioimaging and chemical sensing
JP5264382B2 (ja) * 2008-09-17 2013-08-14 富士フイルム株式会社 画像取得装置
US8157834B2 (en) 2008-11-25 2012-04-17 Ethicon Endo-Surgery, Inc. Rotational coupling device for surgical instrument with flexible actuators
US8937724B2 (en) 2008-12-10 2015-01-20 The General Hospital Corporation Systems and methods for extending imaging depth range of optical coherence tomography through optical sub-sampling
WO2010079484A1 (en) * 2009-01-07 2010-07-15 Given Imaging Ltd. Device and method for detection of an in-vivo pathology
US8361066B2 (en) 2009-01-12 2013-01-29 Ethicon Endo-Surgery, Inc. Electrical ablation devices
JP5315561B2 (ja) * 2009-01-14 2013-10-16 富士フイルム株式会社 撮像装置、撮像方法、及びプログラム
EP2382456A4 (de) * 2009-01-26 2012-07-25 Gen Hospital Corp System, verfahren und computermedium für mikroskopie mit weitem feld und sehr hoher auflösung
JP6053284B2 (ja) * 2009-02-04 2016-12-27 ザ ジェネラル ホスピタル コーポレイション ハイスピード光学波長チューニング源の利用のための装置及び方法
US9351642B2 (en) 2009-03-12 2016-05-31 The General Hospital Corporation Non-contact optical system, computer-accessible medium and method for measurement at least one mechanical property of tissue using coherent speckle technique(s)
US7896498B2 (en) * 2009-03-30 2011-03-01 Ottawa Hospital Research Institute Apparatus and method for optical measurements
DE102009018141A1 (de) * 2009-04-08 2010-10-21 Karl Storz Gmbh & Co. Kg Vorrichtung zur Fluoreszenzdiagnose
US10492671B2 (en) 2009-05-08 2019-12-03 Novadaq Technologies ULC Near infra red fluorescence imaging for visualization of blood vessels during endoscopic harvest
US9492063B2 (en) 2009-06-18 2016-11-15 Endochoice Innovation Center Ltd. Multi-viewing element endoscope
WO2012077117A1 (en) 2010-12-09 2012-06-14 Peermedical Ltd. Flexible electronic circuit board multi-camera endoscope
EP2865322B1 (de) 2009-06-18 2020-07-22 EndoChoice, Inc. Mehrkamera-Endoskop
US9642513B2 (en) 2009-06-18 2017-05-09 Endochoice Inc. Compact multi-viewing element endoscope system
US11278190B2 (en) 2009-06-18 2022-03-22 Endochoice, Inc. Multi-viewing element endoscope
US9713417B2 (en) 2009-06-18 2017-07-25 Endochoice, Inc. Image capture assembly for use in a multi-viewing elements endoscope
US10165929B2 (en) 2009-06-18 2019-01-01 Endochoice, Inc. Compact multi-viewing element endoscope system
US9101268B2 (en) 2009-06-18 2015-08-11 Endochoice Innovation Center Ltd. Multi-camera endoscope
US9901244B2 (en) 2009-06-18 2018-02-27 Endochoice, Inc. Circuit board assembly of a multiple viewing elements endoscope
US9101287B2 (en) 2011-03-07 2015-08-11 Endochoice Innovation Center Ltd. Multi camera endoscope assembly having multiple working channels
US8926502B2 (en) 2011-03-07 2015-01-06 Endochoice, Inc. Multi camera endoscope having a side service channel
US11547275B2 (en) 2009-06-18 2023-01-10 Endochoice, Inc. Compact multi-viewing element endoscope system
US11864734B2 (en) 2009-06-18 2024-01-09 Endochoice, Inc. Multi-camera endoscope
US9872609B2 (en) 2009-06-18 2018-01-23 Endochoice Innovation Center Ltd. Multi-camera endoscope
US9706903B2 (en) 2009-06-18 2017-07-18 Endochoice, Inc. Multiple viewing elements endoscope system with modular imaging units
US9402533B2 (en) 2011-03-07 2016-08-02 Endochoice Innovation Center Ltd. Endoscope circuit board assembly
JP5819823B2 (ja) 2009-07-14 2015-11-24 ザ ジェネラル ホスピタル コーポレイション 血管の内部の流れおよび圧力を測定する装置および装置の作動方法
US8553975B2 (en) 2009-09-21 2013-10-08 Boston Scientific Scimed, Inc. Method and apparatus for wide-band imaging based on narrow-band image data
JP5856061B2 (ja) * 2009-10-06 2016-02-09 ザ ジェネラル ホスピタル コーポレイション スペクトル符号化共焦点顕微鏡法を用いた特定の細胞を撮像するための装置及び方法
EP2485671B1 (de) * 2009-10-06 2019-03-20 Cardiofocus, Inc. Herzablationsbildanalysesystem
US20110098704A1 (en) 2009-10-28 2011-04-28 Ethicon Endo-Surgery, Inc. Electrical ablation devices
JP5711260B2 (ja) * 2009-12-08 2015-04-30 ザ ジェネラル ホスピタル コーポレイション 光コヒーレンストモグラフィにより声帯襞を分析、診断及び治療モニタリングする方法及び装置
US9028483B2 (en) 2009-12-18 2015-05-12 Ethicon Endo-Surgery, Inc. Surgical instrument comprising an electrode
EP2542145B1 (de) 2010-03-05 2020-08-12 The General Hospital Corporation Systeme zur bereitstellung mikroskopischer bilder von mindestens einer anatomischen struktur mit einer bestimmten auflösung
JP5558178B2 (ja) * 2010-04-07 2014-07-23 オリンパス株式会社 蛍光観察装置
US9069130B2 (en) 2010-05-03 2015-06-30 The General Hospital Corporation Apparatus, method and system for generating optical radiation from biological gain media
WO2011150069A2 (en) 2010-05-25 2011-12-01 The General Hospital Corporation Apparatus, systems, methods and computer-accessible medium for spectral analysis of optical coherence tomography images
WO2011149972A2 (en) 2010-05-25 2011-12-01 The General Hospital Corporation Systems, devices, methods, apparatus and computer-accessible media for providing optical imaging of structures and compositions
US10285568B2 (en) 2010-06-03 2019-05-14 The General Hospital Corporation Apparatus and method for devices for imaging structures in or at one or more luminal organs
JP5592715B2 (ja) 2010-07-02 2014-09-17 オリンパス株式会社 画像処理装置および画像処理方法
US9211058B2 (en) * 2010-07-02 2015-12-15 Intuitive Surgical Operations, Inc. Method and system for fluorescent imaging with background surgical image composed of selective illumination spectra
US10682198B2 (en) 2010-07-02 2020-06-16 Intuitive Surgical Operations, Inc. Method and system for fluorescent imaging with background surgical image composed of selective illumination spectra
EP4233680A3 (de) 2010-09-20 2023-09-13 EndoChoice, Inc. Distaler endoskopabschnitt umfassend eine einheitliche flüssigkeitskanal-komponente
US9560953B2 (en) 2010-09-20 2017-02-07 Endochoice, Inc. Operational interface in a multi-viewing element endoscope
JP5604248B2 (ja) * 2010-09-28 2014-10-08 富士フイルム株式会社 内視鏡画像表示装置
JP5496852B2 (ja) * 2010-10-26 2014-05-21 富士フイルム株式会社 電子内視鏡システム、電子内視鏡システムのプロセッサ装置、及び電子内視鏡システムの作動方法
US9510758B2 (en) 2010-10-27 2016-12-06 The General Hospital Corporation Apparatus, systems and methods for measuring blood pressure within at least one vessel
JP5944912B2 (ja) 2010-10-28 2016-07-05 エンドチョイス イノベーション センター リミテッド マルチセンサ内視鏡のための光学系
EP3522215A1 (de) 2010-12-09 2019-08-07 EndoChoice Innovation Center Ltd. Flexible elektronische leiterplatte für ein mehrkamera-endoskop
US11889986B2 (en) 2010-12-09 2024-02-06 Endochoice, Inc. Flexible electronic circuit board for a multi-camera endoscope
JP5570963B2 (ja) * 2010-12-17 2014-08-13 株式会社ミツトヨ 光学式測定装置
EP2656774B1 (de) * 2011-01-31 2016-05-11 Olympus Corporation Fluoreszenzbeobachtungsapparat
EP3228236A1 (de) 2011-02-07 2017-10-11 Endochoice Innovation Center Ltd. Mehrteilige abdeckung für ein mehrkamera-endoskop
US9233241B2 (en) 2011-02-28 2016-01-12 Ethicon Endo-Surgery, Inc. Electrical ablation devices and methods
US9254169B2 (en) 2011-02-28 2016-02-09 Ethicon Endo-Surgery, Inc. Electrical ablation devices and methods
CN107582016B (zh) 2011-03-08 2020-04-28 诺瓦达克技术公司 全光谱led照明器
WO2012125785A1 (en) 2011-03-17 2012-09-20 Ethicon Endo-Surgery, Inc. Hand held surgical device for manipulating an internal magnet assembly within a patient
US8873816B1 (en) 2011-04-06 2014-10-28 Given Imaging Ltd. Method and system for identification of red colored pathologies in vivo
US9134241B2 (en) * 2011-04-11 2015-09-15 Li-Cor, Inc. Differential scan imaging systems and methods
WO2012149175A1 (en) 2011-04-29 2012-11-01 The General Hospital Corporation Means for determining depth-resolved physical and/or optical properties of scattering media
JP5355799B2 (ja) * 2011-06-07 2013-11-27 オリンパスメディカルシステムズ株式会社 内視鏡装置および内視鏡装置の作動方法
CN103347433B (zh) * 2011-06-21 2016-01-20 奥林巴斯株式会社 医疗设备
WO2013013049A1 (en) 2011-07-19 2013-01-24 The General Hospital Corporation Systems, methods, apparatus and computer-accessible-medium for providing polarization-mode dispersion compensation in optical coherence tomography
EP3835718B1 (de) 2011-08-25 2023-07-26 The General Hospital Corporation Vorrichtung zur bereitstellung mikrooptischer kohärenztomographie in einem atmungssystem
JP5926909B2 (ja) 2011-09-07 2016-05-25 オリンパス株式会社 蛍光観察装置
EP2757933B1 (de) 2011-09-22 2019-02-06 The George Washington University Systeme zur visualisierung von ablatiertem gewebe
WO2013044182A1 (en) 2011-09-22 2013-03-28 The George Washington University Systems and methods for visualizing ablated tissue
WO2013066631A1 (en) 2011-10-18 2013-05-10 The General Hospital Corporation Apparatus and methods for producing and/or providing recirculating optical delay(s)
US9179844B2 (en) 2011-11-28 2015-11-10 Aranz Healthcare Limited Handheld skin measuring or monitoring device
EP3659491A1 (de) 2011-12-13 2020-06-03 EndoChoice Innovation Center Ltd. Endoskop mit entfernbarer spitze
CA2798729A1 (en) 2011-12-13 2013-06-13 Peermedical Ltd. Rotatable connector for an endoscope
US10640807B2 (en) 2011-12-29 2020-05-05 S.D. Sight Diagnostics Ltd Methods and systems for detecting a pathogen in a biological sample
WO2013148306A1 (en) 2012-03-30 2013-10-03 The General Hospital Corporation Imaging system, method and distal attachment for multidirectional field of view endoscopy
WO2013148360A1 (en) * 2012-03-30 2013-10-03 Trustees Of Boston University Phase contrast microscopy with oblique back-illumination
WO2013152395A1 (en) * 2012-04-13 2013-10-17 Baker Idi Heart & Diabetes Institute Holdings Limited Atherosclerotic plaque detection
US20150105619A1 (en) * 2012-04-18 2015-04-16 Oncofluor, Inc. Light emitting diode endoscopic devices for visualization of diseased tissue in humans and animals
US9427255B2 (en) 2012-05-14 2016-08-30 Ethicon Endo-Surgery, Inc. Apparatus for introducing a steerable camera assembly into a patient
US11490797B2 (en) 2012-05-21 2022-11-08 The General Hospital Corporation Apparatus, device and method for capsule microscopy
EP2863801B1 (de) 2012-06-21 2024-04-24 Stryker European Operations Limited Quantifizierung und analyse von angiografie und perfusionen
US9078662B2 (en) 2012-07-03 2015-07-14 Ethicon Endo-Surgery, Inc. Endoscopic cap electrode and method for using the same
JP5623469B2 (ja) * 2012-07-06 2014-11-12 富士フイルム株式会社 内視鏡システム、内視鏡システムのプロセッサ装置、及び内視鏡用制御プログラム
WO2014014956A1 (en) 2012-07-17 2014-01-23 The Arizona Board Of Regents On Behalf Of The University Of Arizona Formulaic imaging for tissue diagnosis
US9560954B2 (en) 2012-07-24 2017-02-07 Endochoice, Inc. Connector for use with endoscope
US9545290B2 (en) 2012-07-30 2017-01-17 Ethicon Endo-Surgery, Inc. Needle probe guide
US9572623B2 (en) 2012-08-02 2017-02-21 Ethicon Endo-Surgery, Inc. Reusable electrode and disposable sheath
US10314649B2 (en) 2012-08-02 2019-06-11 Ethicon Endo-Surgery, Inc. Flexible expandable electrode and method of intraluminal delivery of pulsed power
US9277957B2 (en) 2012-08-15 2016-03-08 Ethicon Endo-Surgery, Inc. Electrosurgical devices and methods
JP6227652B2 (ja) 2012-08-22 2017-11-08 ザ ジェネラル ホスピタル コーポレイション ソフトリソグラフィを用いてミニチュア内視鏡を製作するためのシステム、方法、およびコンピュータ・アクセス可能媒体
CN103006168A (zh) * 2012-12-29 2013-04-03 上海乾衡生物科技有限公司 集束光纤快速成像装置
US10893806B2 (en) 2013-01-29 2021-01-19 The General Hospital Corporation Apparatus, systems and methods for providing information regarding the aortic valve
WO2014121082A1 (en) 2013-02-01 2014-08-07 The General Hospital Corporation Objective lens arrangement for confocal endomicroscopy
US10098527B2 (en) 2013-02-27 2018-10-16 Ethidcon Endo-Surgery, Inc. System for performing a minimally invasive surgical procedure
JP6378311B2 (ja) 2013-03-15 2018-08-22 ザ ジェネラル ホスピタル コーポレイション 物体を特徴付ける方法とシステム
US9993142B2 (en) 2013-03-28 2018-06-12 Endochoice, Inc. Fluid distribution device for a multiple viewing elements endoscope
US9986899B2 (en) 2013-03-28 2018-06-05 Endochoice, Inc. Manifold for a multiple viewing elements endoscope
US10499794B2 (en) 2013-05-09 2019-12-10 Endochoice, Inc. Operational interface in a multi-viewing element endoscope
WO2014186353A1 (en) 2013-05-13 2014-11-20 The General Hospital Corporation Detecting self-interefering fluorescence phase and amplitude
WO2014188405A1 (en) 2013-05-23 2014-11-27 Parasight Ltd. Method and system for imaging a cell sample
IL227276A0 (en) 2013-07-01 2014-03-06 Parasight Ltd A method and system for obtaining a monolayer of cells, for use specifically for diagnosis
EP3021735A4 (de) 2013-07-19 2017-04-19 The General Hospital Corporation Bestimmung der augenbewegung mittels netzhautabbildung mit rückkopplung
EP4349242A2 (de) 2013-07-19 2024-04-10 The General Hospital Corporation Bildgebungsvorrichtung und verfahren mit multidirektionaler sichtfeldendoskopie
WO2015013651A2 (en) 2013-07-26 2015-01-29 The General Hospital Corporation System, apparatus and method utilizing optical dispersion for fourier-domain optical coherence tomography
US9324145B1 (en) 2013-08-08 2016-04-26 Given Imaging Ltd. System and method for detection of transitions in an image stream of the gastrointestinal tract
WO2015042529A2 (en) 2013-09-20 2015-03-26 The Regents Of The University Of California Methods, systems, and devices for imaging microscopic tumors
JP6737705B2 (ja) 2013-11-14 2020-08-12 ザ・ジョージ・ワシントン・ユニバーシティＴｈｅ Ｇｅｏｒｇｅ Ｗａｓｈｉｎｇｔｏｎｕｎｉｖｅｒｓｉｔｙ 損傷部位の深さを決定するシステムの動作方法及び心臓組織の画像を生成するシステム
JP2017500550A (ja) 2013-11-20 2017-01-05 ザ・ジョージ・ワシントン・ユニバーシティＴｈｅ Ｇｅｏｒｇｅ Ｗａｓｈｉｎｇｔｏｎｕｎｉｖｅｒｓｉｔｙ 心臓組織のハイパースペクトル分析のためのシステム及び方法
US10602917B2 (en) 2013-12-31 2020-03-31 Karl Storz Imaging, Inc. Switching between white light imaging and excitation light imaging leaving last video frame displayed
US10602918B2 (en) 2013-12-31 2020-03-31 Karl Storz Imaging, Inc. Switching between white light imaging and excitation light imaging leaving last video frame displayed
US9733460B2 (en) 2014-01-08 2017-08-15 The General Hospital Corporation Method and apparatus for microscopic imaging
US10117563B2 (en) * 2014-01-09 2018-11-06 Gyrus Acmi, Inc. Polyp detection from an image
US10736494B2 (en) 2014-01-31 2020-08-11 The General Hospital Corporation System and method for facilitating manual and/or automatic volumetric imaging with real-time tension or force feedback using a tethered imaging device
US10228556B2 (en) 2014-04-04 2019-03-12 The General Hospital Corporation Apparatus and method for controlling propagation and/or transmission of electromagnetic radiation in flexible waveguide(s)
JP6005303B2 (ja) * 2014-04-08 2016-10-12 オリンパス株式会社 蛍光観察内視鏡システム
EP3957232A1 (de) 2014-07-24 2022-02-23 University Health Network Sammlung und analyse von daten für diagnostische zwecke
KR102513779B1 (ko) 2014-07-25 2023-03-24 더 제너럴 하스피탈 코포레이션 생체 내 이미징 및 진단을 위한 장치, 디바이스 및 방법
EP3201607B1 (de) * 2014-09-29 2020-12-30 Novadaq Technologies ULC Bildgebung eines zielfluorophors in einem biologischen material in anwesenheit von autofluoreszenz
KR102012880B1 (ko) 2014-10-09 2019-08-22 노바다크 테크놀러지즈 유엘씨 형광-조정 광전용적맥파 측정기를 사용한 조직 내의 절대적인 혈류의 정량화
KR102499045B1 (ko) 2014-11-03 2023-02-10 더 조지 워싱턴 유니버시티 병변 평가를 위한 시스템 및 방법
JP6771731B2 (ja) 2014-11-03 2020-10-21 ４６０メディカル・インコーポレイテッド４６０Ｍｅｄｉｃａｌ， Ｉｎｃ． 接触性評価システム及び方法
EP3730086B1 (de) * 2014-12-16 2023-06-28 Intuitive Surgical Operations, Inc. Harnleitererkennung unter verwendung von wellenbandselektiver bildgebung
US10779904B2 (en) 2015-07-19 2020-09-22 460Medical, Inc. Systems and methods for lesion formation and assessment
WO2017047141A1 (ja) * 2015-09-14 2017-03-23 オリンパス株式会社 内視鏡装置及び内視鏡システム
EP3859425B1 (de) 2015-09-17 2024-04-17 S.D. Sight Diagnostics Ltd. Verfahren und vorrichtung zur detektion einer entität in einer körperprobe
CN113648067A (zh) 2015-11-13 2021-11-16 史赛克欧洲运营有限公司 用于目标的照明和成像的系统和方法
EP3408654B1 (de) 2016-01-26 2022-08-03 Stryker European Operations Limited Flurorezenzbildgebungssystem und methode zur fluoreszenzbildgebung
US10293122B2 (en) 2016-03-17 2019-05-21 Novadaq Technologies ULC Endoluminal introducer with contamination avoidance
US11733150B2 (en) 2016-03-30 2023-08-22 S.D. Sight Diagnostics Ltd. Distinguishing between blood sample components
EP3442397B1 (de) 2016-04-13 2021-06-09 Inspektor Research Systems B.V. Zahnuntersuchung mit doppelfrequenz
USD916294S1 (en) 2016-04-28 2021-04-13 Stryker European Operations Limited Illumination and imaging device
US10013527B2 (en) 2016-05-02 2018-07-03 Aranz Healthcare Limited Automatically assessing an anatomical surface feature and securely managing information related to the same
EP3455610B1 (de) 2016-05-11 2023-01-04 S.D. Sight Diagnostics Ltd. Probenträger für optische messungen
WO2017214730A1 (en) 2016-06-14 2017-12-21 Novadaq Technologies Inc. Methods and systems for adaptive imaging for low light signal enhancement in medical visualization
US11116407B2 (en) 2016-11-17 2021-09-14 Aranz Healthcare Limited Anatomical surface assessment methods, devices and systems
DE102016125524A1 (de) 2016-12-22 2018-06-28 Arnold & Richter Cine Technik Gmbh & Co. Betriebs Kg Elektronisches Mikroskop
WO2018145193A1 (en) 2017-02-10 2018-08-16 Novadaq Technologies ULC Open-field handheld fluorescence imaging systems and methods
US10395770B2 (en) * 2017-02-16 2019-08-27 General Electric Company Systems and methods for monitoring a patient
WO2018185560A2 (en) 2017-04-04 2018-10-11 Aranz Healthcare Limited Anatomical surface assessment methods, devices and systems
US11921272B2 (en) 2017-11-14 2024-03-05 S.D. Sight Diagnostics Ltd. Sample carrier for optical measurements
CN108107032B (zh) * 2018-01-29 2024-03-15 北京博晖创新光电技术股份有限公司 一种原子荧光光谱仪
US11382487B2 (en) 2018-04-03 2022-07-12 Curadel, LLC Micro CMOS scopes for medical imaging
US11625825B2 (en) 2019-01-30 2023-04-11 Covidien Lp Method for displaying tumor location within endoscopic images
EP3998936A4 (de) 2019-07-17 2022-08-31 Nxgenport, L.L.C. Implantierbarer venenzugangsport mit entfernten physiologischen überwachungsfähigkeiten
BR112022011354A2 (pt) * 2019-12-12 2022-08-23 S D Sight Diagnostics Ltd Geração artificial de uma imagem colorida de esfregaço sanguíneo

Family Cites Families (58)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58141135A (ja) * 1981-10-20 1983-08-22 富士写真フイルム株式会社 固体イメ−ジセンサを用いた内視鏡の画像伝送方式
JPS58222331A (ja) * 1982-06-21 1983-12-24 Sony Corp 文字情報再生装置
JPS5940830A (ja) * 1982-08-31 1984-03-06 浜松ホトニクス株式会社 レ−ザ光パルスを用いた癌の診断装置
JPS59139237A (ja) * 1983-01-31 1984-08-10 熊谷　博彰 螢光分光画像解析装置
US4541438A (en) * 1983-06-02 1985-09-17 The Johns Hopkins University Localization of cancerous tissue by monitoring infrared fluorescence emitted by intravenously injected porphyrin tumor-specific markers excited by long wavelength light
JPS60256443A (ja) * 1984-05-31 1985-12-18 オムロン株式会社 画像計測装置
JP2655568B2 (ja) * 1984-08-31 1997-09-24 オリンパス光学工業株式会社 固体撮像素子を用いた内視鏡
SE455646B (sv) * 1984-10-22 1988-07-25 Radians Innova Ab Fluorescensanordning
US5318024A (en) * 1985-03-22 1994-06-07 Massachusetts Institute Of Technology Laser endoscope for spectroscopic imaging
US4718417A (en) * 1985-03-22 1988-01-12 Massachusetts Institute Of Technology Visible fluorescence spectral diagnostic for laser angiosurgery
US5125404A (en) * 1985-03-22 1992-06-30 Massachusetts Institute Of Technology Apparatus and method for obtaining spectrally resolved spatial images of tissue
US4913142A (en) * 1985-03-22 1990-04-03 Massachusetts Institute Of Technology Catheter for laser angiosurgery
CN85100424B (zh) * 1985-04-01 1986-10-29 上海医疗器械研究所 恶性肿瘤固有荧光诊断仪
AT387860B (de) * 1985-09-16 1989-03-28 Optical Sensing Technology Verfahren und vorrichtung zur tumordiagnose mittels sera
DE3633444A1 (de) * 1985-10-02 1987-04-09 Olympus Optical Co Endoskopische fotografiervorrichtung
US5042494A (en) * 1985-11-13 1991-08-27 Alfano Robert R Method and apparatus for detecting cancerous tissue using luminescence excitation spectra
US4930516B1 (en) * 1985-11-13 1998-08-04 Laser Diagnostic Instr Inc Method for detecting cancerous tissue using visible native luminescence
US4774568A (en) * 1986-01-27 1988-09-27 Kabushiki Kaisha Toshiba Endoscopic apparatus
JPS62247232A (ja) * 1986-04-21 1987-10-28 Agency Of Ind Science & Technol 蛍光測定装置
GB2203831B (en) * 1986-07-07 1991-02-06 Academy Of Applied Sciences Apparatus and method for the diagnosis of malignant tumours
JPS6379632A (ja) * 1986-09-25 1988-04-09 株式会社東芝 電子内視鏡装置
JPH0763443B2 (ja) * 1986-09-30 1995-07-12 株式会社東芝 電子内視鏡
JPS63122421A (ja) * 1986-11-12 1988-05-26 株式会社東芝 内視鏡装置
US5255087A (en) * 1986-11-29 1993-10-19 Olympus Optical Co., Ltd. Imaging apparatus and endoscope apparatus using the same
JP2572394B2 (ja) * 1987-03-19 1997-01-16 オリンパス光学工業株式会社 電子内視鏡
JPH0783B2 (ja) * 1987-03-30 1995-01-11 株式会社東芝 電子内視鏡装置
US4986262A (en) * 1987-03-31 1991-01-22 Kabushiki Kaisha Toshiba Measuring endoscope
US4852579A (en) * 1987-04-20 1989-08-01 Karl Storz Endoscopy Gmbh And Company Photocharacterization and treatment of normal abnormal and ectopic endometrium
US4900934A (en) * 1987-07-15 1990-02-13 University Of Utah Apparatus for simultaneous visualization and measurement of fluorescence from fluorescent dye-treated cell preparations and solutions
US4878113A (en) * 1987-08-11 1989-10-31 Olympus Optical Co., Ltd. Endoscope apparatus
JPH0824668B2 (ja) * 1987-09-14 1996-03-13 オリンパス光学工業株式会社 電子内視鏡装置
US4858001A (en) * 1987-10-08 1989-08-15 High-Tech Medical Instrumentation, Inc. Modular endoscopic apparatus with image rotation
JPH01160525A (ja) * 1987-12-17 1989-06-23 Olympus Optical Co Ltd 内視鏡
US4928172A (en) * 1988-01-07 1990-05-22 Olympus Optical Co., Ltd. Endoscope output signal control device and endoscope apparatus making use of the same
JPH06105190B2 (ja) * 1988-03-31 1994-12-21 工業技術院長 信号解析装置
US4998972A (en) * 1988-04-28 1991-03-12 Thomas J. Fogarty Real time angioscopy imaging system
US5078150A (en) * 1988-05-02 1992-01-07 Olympus Optical Co., Ltd. Spectral diagnosing apparatus with endoscope
US4938205A (en) * 1988-05-27 1990-07-03 The University Of Connecticut Endoscope with traced raster and elemental photodetectors
US4981138A (en) * 1988-06-30 1991-01-01 Yale University Endoscopic fiberoptic fluorescence spectrometer
US5442438A (en) * 1988-12-22 1995-08-15 Renishaw Plc Spectroscopic apparatus and methods
SE8900612D0 (sv) * 1989-02-22 1989-02-22 Jonas Johansson Vaevnadskarakterisering utnyttjande ett blodfritt fluorescenskriterium
US5421337A (en) * 1989-04-14 1995-06-06 Massachusetts Institute Of Technology Spectral diagnosis of diseased tissue
EP0466828A1 (de) * 1989-04-14 1992-01-22 Massachusetts Institute Of Technology Spektraldiagnose von erkranktem gewebe
US4993404A (en) * 1989-06-26 1991-02-19 Lane Timothy G Fluoroscopy switching device
US5091652A (en) * 1990-01-12 1992-02-25 The Regents Of The University Of California Laser excited confocal microscope fluorescence scanner and method
US5131398A (en) * 1990-01-22 1992-07-21 Mediscience Technology Corp. Method and apparatus for distinguishing cancerous tissue from benign tumor tissue, benign tissue or normal tissue using native fluorescence
US5071417A (en) * 1990-06-15 1991-12-10 Rare Earth Medical Lasers, Inc. Laser fusion of biological materials
GB2250089A (en) * 1990-11-21 1992-05-27 Philips Electronic Associated Spectrometer
JPH04307024A (ja) * 1991-04-02 1992-10-29 Olympus Optical Co Ltd 電子内視鏡装置
US5377676A (en) * 1991-04-03 1995-01-03 Cedars-Sinai Medical Center Method for determining the biodistribution of substances using fluorescence spectroscopy
US5318023A (en) * 1991-04-03 1994-06-07 Cedars-Sinai Medical Center Apparatus and method of use for a photosensitizer enhanced fluorescence based biopsy needle
US5117466A (en) * 1991-04-30 1992-05-26 The United States Of America As Represented By The United States Department Of Energy Integrated fluorescence analysis system
CA2042075C (en) * 1991-05-08 2001-01-23 Branko Palcic Endoscopic imaging system
US5408996A (en) * 1993-03-25 1995-04-25 Salb; Jesse System and method for localization of malignant tissue
US5421339A (en) * 1993-05-12 1995-06-06 Board Of Regents, The University Of Texas System Diagnosis of dysplasia using laser induced fluoroescence
US5408998A (en) * 1994-03-10 1995-04-25 Ethicon Endo-Surgery Video based tissue oximetry
US5590660A (en) * 1994-03-28 1997-01-07 Xillix Technologies Corp. Apparatus and method for imaging diseased tissue using integrated autofluorescence
US5697373A (en) * 1995-03-14 1997-12-16 Board Of Regents, The University Of Texas System Optical method and apparatus for the diagnosis of cervical precancers using raman and fluorescence spectroscopies

Cited By (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102008011013B4 (de) * 2008-02-25 2014-11-13 Mevitec Gmbh Verfahren und Einrichtung zur komplexen Stoffwechselanalyse
DE102008011013A1 (de) 2008-02-25 2009-09-03 Labo Tech Labortechnik Gmbh Verfahren und Einrichtung zur komplexen Stoffwechselanalyse
DE102008062650B4 (de) 2008-12-17 2021-08-12 Carl Zeiss Meditec Ag Operationsmikroskop zur Beobachtung einer Infrarot-Fluoreszenz und Verfahren hierzu
US8659651B2 (en) 2008-12-17 2014-02-25 Carl Zeiss Meditec Ag Surgical microscope for observing an infrared fluorescence and corresponding method
DE102008062650A1 (de) * 2008-12-17 2010-07-15 Carl Zeiss Surgical Gmbh Operationsmikroskop zur Beobachtung einer Infrarot-Fluoreszenz und Verfahren hierzu
DE102008062650B9 (de) 2008-12-17 2021-10-28 Carl Zeiss Meditec Ag Operationsmikroskop zur Beobachtung einer Infrarot-Fluoreszenz und Verfahren hierzu
DE102012002086A1 (de) * 2012-02-06 2013-08-08 Carl Zeiss Meditec Ag Verfahren zum Untersuchen von biologischem Gewebe und Vorrichtungen zum Untersuchen und Behandeln des Gewebes
US9883804B2 (en) 2012-02-06 2018-02-06 Carl Zeiss Meditec Ag Method and device for examining a biological tissue by analysing fluorescence response to illumination and for treating the tissue
US10973411B2 (en) 2012-02-06 2021-04-13 Carl Zeiss Meditec Ag Method and device for examining a biological tissue by analysing fluorescence response to illumination and for treating the tissue
DE102015011441A1 (de) * 2015-09-01 2017-03-02 Carl Zeiss Meditec Ag Fluoreszenzlichtdetektionssystem und Mikroskopiesystem
DE102017203452A1 (de) 2017-03-02 2018-09-06 Carl Zeiss Meditec Ag Fluoreszenzbeobachtungssystem
DE102017203452B4 (de) 2017-03-02 2021-09-09 Carl Zeiss Meditec Ag Fluoreszenzbeobachtungssystem
DE102017203452B9 (de) 2017-03-02 2021-12-09 Carl Zeiss Meditec Ag Fluoreszenzbeobachtungssystem

Also Published As

Publication number Publication date
DE69518915D1 (de) 2000-10-26
JP2004154592A (ja) 2004-06-03
US5827190A (en) 1998-10-27
WO1995026673A2 (en) 1995-10-12
DE69535270D1 (de) 2006-11-23
EP1472972A1 (de) 2004-11-03
JP3694667B2 (ja) 2005-09-14
EP0920831B1 (de) 2005-08-17
EP1472972B1 (de) 2006-10-11
DE69534388T2 (de) 2006-05-24
EP0752825A1 (de) 1997-01-15
DE69534388D1 (de) 2005-09-22
JP3683271B2 (ja) 2005-08-17
WO1995026673A3 (en) 1995-11-23
DE69535270T2 (de) 2007-04-19
JPH10500588A (ja) 1998-01-20
EP0752825B1 (de) 2000-09-20
US5590660A (en) 1997-01-07
JP2002301009A (ja) 2002-10-15
EP0920831A1 (de) 1999-06-09

Similar Documents

Publication Publication Date Title
DE69518915T2 (de) Verfahren und vorrichtung zur bilderzeugung von erkranktem gewebe unter verwendung der integrierten autofluoreszenz
DE69535165D1 (de) Verfahren und Vorrichtung zur Bohrlochuntersuchung
DE69704264D1 (de) Verfahren und Vorrichtung zur nichtinvasiven Bestimmung der Konzentration einer Komponente
DE59812406D1 (de) Verfahren und Vorrichtung zur kontinuierlichen Überwachung einer extrakorporalen Blutbehandlung
DE19882669T1 (de) Vorrichtung und Verfahren zur Pflege der Ferse
DE69414913D1 (de) Verfahren und Vorrichtung zur Gewinnung von Bildern der Hornhaut
DE59510184D1 (de) Einrichtung und verfahren zur hautuntersuchung
DE69829336D1 (de) Vorrichtung und Verfahren zur Behandlung von Körpergewebe
ATE208147T1 (de) Verfahren und vorrichtung zur herstellung von kleidungstück nach mass
DE69828571D1 (de) Blutfiltersatz und zugehöriges Verfahren zur Gewinnung von Blutkomponenten
DE69739827D1 (de) Belichtungsapparat und Verfahren zur Herstellung einer Vorrichtung unter Verwendung desselben
DE69807538D1 (de) Vorrichtung und Verfahren zur Behandlung von Gewebe
DE69619611D1 (de) Verfahren und Vorrichtung zur Bestimmung der petrologischen Eigenschaften von Schichtgesteinen
DE69723865D1 (de) Verfahren und vorrichtung zur herstellung von einkristallen
DE69838512D1 (de) Verfahren und vorrichtung zur herstellung reines wasser
DE69818413D1 (de) Bildherstellungverfahren und Vorrichtung zur Bildherstellung
DE69734980D1 (de) Verfahren und vorrichtung zur herstellung von weichem tissuepapier
DE59603567D1 (de) Vorrichtung zur stimulation der gewebsneubildung bei gewebsdefekten
DE59705140D1 (de) Verfahren und Vorrichtung zur Herstellung von Einkristallen
DE69706162D1 (de) Verfahren und gerät zur bestimmung der qualität von kulturpflanzen
DE69838567D1 (de) Verfahren und Vorrichtung zur Herstellung von Photographischen Bildern
DE69731167D1 (de) Verfahren und Vorrichtung zur Auswertung von Stereo-Aufnahmen des Augenhintergrunds
DE69704637D1 (de) Vorrichtung und Verfahren zur Herstellung von Einkristallen
DE59808923D1 (de) Vorrichtung und verfahren zur herstellung von siliconemulsionen
DE69510556T2 (de) Vorrichtung und verfahren zur abbildung der hautrippen

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: NOVADAQ TECHNOLOGIES INC., MISSISSAUGA, ONTARI, CA