DE69330879T2 - Verwendung von hydrogelen für die befestigung von knochenersatzmaterialen - Google Patents
Verwendung von hydrogelen für die befestigung von knochenersatzmaterialenInfo
- Publication number
- DE69330879T2 DE69330879T2 DE69330879T DE69330879T DE69330879T2 DE 69330879 T2 DE69330879 T2 DE 69330879T2 DE 69330879 T DE69330879 T DE 69330879T DE 69330879 T DE69330879 T DE 69330879T DE 69330879 T2 DE69330879 T2 DE 69330879T2
- Authority
- DE
- Germany
- Prior art keywords
- pct
- hyaluronic acid
- replacements
- hydrogels
- bone
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L31/16—Biologically active materials, e.g. therapeutic substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/08—Materials for coatings
- A61L31/10—Macromolecular materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/12—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
- A61L31/125—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
- A61L31/127—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix containing fillers of phosphorus-containing inorganic materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L31/145—Hydrogels or hydrocolloids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
- A61L2300/606—Coatings
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S623/00—Prosthesis, i.e. artificial body members, parts thereof, or aids and accessories therefor
- Y10S623/901—Method of manufacturing prosthetic device
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ITPD920088A IT1259100B (it) | 1992-05-20 | 1992-05-20 | Uso di idrogeli per il bloccaggio di sistemi protesici |
PCT/EP1993/001288 WO1993023094A1 (en) | 1992-05-20 | 1993-05-21 | Use of hydrogels to fix bone replacements |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69330879D1 DE69330879D1 (de) | 2001-11-08 |
DE69330879T2 true DE69330879T2 (de) | 2002-06-13 |
Family
ID=11389935
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69330879T Expired - Lifetime DE69330879T2 (de) | 1992-05-20 | 1993-05-21 | Verwendung von hydrogelen für die befestigung von knochenersatzmaterialen |
Country Status (6)
Country | Link |
---|---|
US (1) | US5645592A (de) |
EP (1) | EP0642363B1 (de) |
AT (1) | ATE206316T1 (de) |
DE (1) | DE69330879T2 (de) |
IT (1) | IT1259100B (de) |
WO (1) | WO1993023094A1 (de) |
Families Citing this family (97)
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US6150328A (en) * | 1986-07-01 | 2000-11-21 | Genetics Institute, Inc. | BMP products |
AU674500B2 (en) | 1991-11-04 | 1997-01-02 | Genetics Institute, Llc | Recombinant bone morphogenetic protein heterodimers, compositions and methods of use |
US20080070842A1 (en) * | 1991-11-04 | 2008-03-20 | David Israel | Recombinant bone morphogenetic protein heterodimers, compositions and methods of use |
US6291206B1 (en) * | 1993-09-17 | 2001-09-18 | Genetics Institute, Inc. | BMP receptor proteins |
ITPD940011A1 (it) * | 1994-01-28 | 1995-07-28 | Fidia Advanced Biopolymers Srl | Rivestimento di oggetti biomedicali mediante microsfere ottenute da polimeri biocompatibili |
EP0700671B1 (de) * | 1994-09-08 | 2001-08-08 | Stryker Technologies Corporation | Bandscheibenkern aus Hydrogel |
US5718717A (en) | 1996-08-19 | 1998-02-17 | Bonutti; Peter M. | Suture anchor |
US6071982A (en) * | 1997-04-18 | 2000-06-06 | Cambridge Scientific, Inc. | Bioerodible polymeric semi-interpenetrating network alloys for surgical plates and bone cements, and method for making same |
US5837752A (en) * | 1997-07-17 | 1998-11-17 | Massachusetts Institute Of Technology | Semi-interpenetrating polymer networks |
ATE228021T1 (de) * | 1998-09-11 | 2002-12-15 | Gerhard Dr Schmidmaier | Biologisch aktive implantate |
US6727224B1 (en) * | 1999-02-01 | 2004-04-27 | Genetics Institute, Llc. | Methods and compositions for healing and repair of articular cartilage |
US6358283B1 (en) | 1999-06-21 | 2002-03-19 | Hoegfors Christian | Implantable device for lengthening and correcting malpositions of skeletal bones |
AU7628700A (en) | 1999-08-04 | 2001-03-05 | Cbyon, Inc. | Biodegradable spinal fiducial implant and method |
US6368343B1 (en) | 2000-03-13 | 2002-04-09 | Peter M. Bonutti | Method of using ultrasonic vibration to secure body tissue |
US6447516B1 (en) | 1999-08-09 | 2002-09-10 | Peter M. Bonutti | Method of securing tissue |
DK1223990T3 (da) * | 1999-10-15 | 2004-11-29 | Inst Genetics Llc | Formuleringer af hyaluronsyre til tilförsel af osteogene proteiner |
US6579533B1 (en) * | 1999-11-30 | 2003-06-17 | Bioasborbable Concepts, Ltd. | Bioabsorbable drug delivery system for local treatment and prevention of infections |
US9138222B2 (en) | 2000-03-13 | 2015-09-22 | P Tech, Llc | Method and device for securing body tissue |
US7094251B2 (en) | 2002-08-27 | 2006-08-22 | Marctec, Llc. | Apparatus and method for securing a suture |
US20030082233A1 (en) * | 2000-12-01 | 2003-05-01 | Lyons Karen M. | Method and composition for modulating bone growth |
ES2305246T3 (es) * | 2001-06-01 | 2008-11-01 | Wyeth | Composiciones para la administracion sistemica de secuencias que codifican proteinas oseas morfogeneticas. |
TWI267378B (en) * | 2001-06-08 | 2006-12-01 | Wyeth Corp | Calcium phosphate delivery vehicles for osteoinductive proteins |
US6719765B2 (en) | 2001-12-03 | 2004-04-13 | Bonutti 2003 Trust-A | Magnetic suturing system and method |
US9155544B2 (en) | 2002-03-20 | 2015-10-13 | P Tech, Llc | Robotic systems and methods |
TW200638946A (en) * | 2002-05-17 | 2006-11-16 | Wyeth Corp | Injectable solid hyaluronic acid carriers for delivery of osteogenic proteins |
US7820638B2 (en) * | 2002-08-09 | 2010-10-26 | Arthrex, Inc. | Method of applying hyaluronic acid to implant or graft to enhance lubricity and cellular density |
US7497864B2 (en) | 2003-04-30 | 2009-03-03 | Marctec, Llc. | Tissue fastener and methods for using same |
US8246974B2 (en) | 2003-05-02 | 2012-08-21 | Surmodics, Inc. | Medical devices and methods for producing the same |
ATE476960T1 (de) | 2003-05-02 | 2010-08-15 | Surmodics Inc | System zur kontrollierten freisetzung eines bioaktiven wirkstoffs im hinteren bereich des auges |
CN1878565B (zh) * | 2003-09-12 | 2011-01-12 | 惠氏公司 | 用于递送成骨蛋白的注射型磷酸钙固体小棒剂和糊剂 |
US20050095269A1 (en) * | 2003-11-04 | 2005-05-05 | Ainpour Parviz R. | Gel plug for blockage of the canaliculus |
US20090240276A1 (en) * | 2003-11-04 | 2009-09-24 | Parviz Robert Ainpour | Gel Plug For Blockage Of The Canaliculus |
US7670377B2 (en) | 2003-11-21 | 2010-03-02 | Kyphon Sarl | Laterally insertable artifical vertebral disk replacement implant with curved spacer |
WO2005077013A2 (en) | 2004-02-06 | 2005-08-25 | Georgia Tech Research Corporation | Surface directed cellular attachment |
US7910124B2 (en) | 2004-02-06 | 2011-03-22 | Georgia Tech Research Corporation | Load bearing biocompatible device |
US8666486B2 (en) * | 2004-03-04 | 2014-03-04 | Hadasit Medical Research Services & Development Limited | Safe device for iontophoretic delivery of drugs |
US20080039873A1 (en) | 2004-03-09 | 2008-02-14 | Marctec, Llc. | Method and device for securing body tissue |
US20060024350A1 (en) * | 2004-06-24 | 2006-02-02 | Varner Signe E | Biodegradable ocular devices, methods and systems |
WO2006023130A2 (en) * | 2004-08-12 | 2006-03-02 | Surmodics, Inc. | Biodegradable controlled release bioactive agent delivery device |
US20090088846A1 (en) | 2007-04-17 | 2009-04-02 | David Myung | Hydrogel arthroplasty device |
CN101052427B (zh) * | 2004-10-06 | 2011-09-14 | 诺比尔生物研究所有限公司 | 透明质酸涂覆的植入器械、制备所述植入器械的方法、以及透明质酸在制备所述植入器械中的用途 |
US9173647B2 (en) | 2004-10-26 | 2015-11-03 | P Tech, Llc | Tissue fixation system |
US20060089646A1 (en) | 2004-10-26 | 2006-04-27 | Bonutti Peter M | Devices and methods for stabilizing tissue and implants |
US9463012B2 (en) | 2004-10-26 | 2016-10-11 | P Tech, Llc | Apparatus for guiding and positioning an implant |
US9271766B2 (en) | 2004-10-26 | 2016-03-01 | P Tech, Llc | Devices and methods for stabilizing tissue and implants |
US8663225B2 (en) | 2004-11-12 | 2014-03-04 | Medtronic, Inc. | Hydrogel bone void filler |
WO2006081379A1 (en) * | 2005-01-26 | 2006-08-03 | Wyeth | Use of sfrps as markers of bmp activity |
US9089323B2 (en) | 2005-02-22 | 2015-07-28 | P Tech, Llc | Device and method for securing body tissue |
EP1851268A4 (de) * | 2005-02-23 | 2011-02-16 | Univ California | Flexible, funktionelle verbundwerkstoffe auf hydrogelbasis |
EP1863518A2 (de) * | 2005-03-30 | 2007-12-12 | Wyeth | VERFAHREN ZUR STIMULATION DES WAARWACHSTUMS MITTELS VERABREICHUNG VON BMPs |
US20060224244A1 (en) * | 2005-03-31 | 2006-10-05 | Zimmer Technology, Inc. | Hydrogel implant |
US20060235542A1 (en) * | 2005-04-15 | 2006-10-19 | Zimmer Technology, Inc. | Flexible segmented bearing implant |
US20060257358A1 (en) * | 2005-05-13 | 2006-11-16 | Depuy Products, Inc. | Suspension of calcium phosphate particulates for local delivery of therapeutic agents |
US20060257492A1 (en) * | 2005-05-13 | 2006-11-16 | Depuy Products, Inc. | Suspension of calcium phosphate particulates for local delivery of therapeutic agents |
JP2009505762A (ja) * | 2005-08-31 | 2009-02-12 | ツィンマー・ゲーエムベーハー | インプラント |
US20070088444A1 (en) * | 2005-10-13 | 2007-04-19 | Robert A Hodorek | Method for repairing a bone defect using a formable implant which hardens in vivo |
US8308807B2 (en) * | 2005-11-09 | 2012-11-13 | Zimmer, Gmbh | Implant with differential anchoring |
US20070179607A1 (en) * | 2006-01-31 | 2007-08-02 | Zimmer Technology, Inc. | Cartilage resurfacing implant |
US7967820B2 (en) | 2006-02-07 | 2011-06-28 | P Tech, Llc. | Methods and devices for trauma welding |
US11253296B2 (en) | 2006-02-07 | 2022-02-22 | P Tech, Llc | Methods and devices for intracorporeal bonding of implants with thermal energy |
US11278331B2 (en) | 2006-02-07 | 2022-03-22 | P Tech Llc | Method and devices for intracorporeal bonding of implants with thermal energy |
US8496657B2 (en) | 2006-02-07 | 2013-07-30 | P Tech, Llc. | Methods for utilizing vibratory energy to weld, stake and/or remove implants |
US20090048679A1 (en) * | 2006-02-09 | 2009-02-19 | Zimmer Gmbh | Implant |
US8632601B2 (en) * | 2006-04-28 | 2014-01-21 | Zimmer, Gmbh | Implant |
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US8617185B2 (en) | 2007-02-13 | 2013-12-31 | P Tech, Llc. | Fixation device |
US8979935B2 (en) * | 2007-07-31 | 2015-03-17 | Zimmer, Inc. | Joint space interpositional prosthetic device with internal bearing surfaces |
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US20090265016A1 (en) * | 2008-04-21 | 2009-10-22 | Lasse Daniel Efskind | Material for surgical use in traumatology |
US10022164B2 (en) * | 2008-06-11 | 2018-07-17 | Eventions, Llc | Orthopedic fastener device |
US20120209396A1 (en) | 2008-07-07 | 2012-08-16 | David Myung | Orthopedic implants having gradient polymer alloys |
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EP2400899A4 (de) | 2009-02-24 | 2015-03-18 | P Tech Llc | Verfahren und vorrichtungen zur verwendung bindbarer materialien |
US8668739B2 (en) | 2010-08-20 | 2014-03-11 | Zimmer, Inc. | Unitary orthopedic implant |
EP2609154B1 (de) | 2010-08-27 | 2020-04-22 | Hyalex Orthopaedics, Inc. | Aus hydrophoben polymeren gewonnene interpenetrierende hydrophobe und hydrophile polymernetzwerke sowie verfahren zu ihrer herstellung |
US8676319B2 (en) | 2010-10-29 | 2014-03-18 | Medtronic, Inc. | Implantable medical device with compressible fixation member |
CA2823954A1 (en) * | 2011-01-10 | 2012-07-19 | Biomimedica, Inc. | Orthopedic implants having gradient polymer alloys |
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AU2012319183A1 (en) | 2011-10-03 | 2014-05-22 | Biomimedica, Inc. | Polymeric adhesive for anchoring compliant materials to another surface |
EP2782524B1 (de) | 2011-11-21 | 2017-12-20 | Biomimedica, Inc | Systeme zum verankern orthopädischer implantate in knochen |
US9682035B2 (en) | 2012-02-23 | 2017-06-20 | The Board Of Trustees Of The Leland Stanford Junior University | Injectable hydrogel system to modulate host response at bone implant interface |
JP6549482B2 (ja) | 2012-06-01 | 2019-07-24 | サーモディクス,インコーポレイテッド | バルーンカテーテルをコーティングするための装置および方法 |
US9827401B2 (en) | 2012-06-01 | 2017-11-28 | Surmodics, Inc. | Apparatus and methods for coating medical devices |
US11090468B2 (en) | 2012-10-25 | 2021-08-17 | Surmodics, Inc. | Apparatus and methods for coating medical devices |
US10076377B2 (en) | 2013-01-05 | 2018-09-18 | P Tech, Llc | Fixation systems and methods |
CN105188667A (zh) * | 2013-03-27 | 2015-12-23 | 佛多斯大学医学研究中心(C·H·U·V) | 用于治疗和/或预防再狭窄的药物制剂 |
DE102015102210A1 (de) | 2015-02-16 | 2016-08-18 | Heraeus Medical Gmbh | Antimykotischer polymerisierbarer Knochenzement und ein Verfahren zu seiner Herstellung |
CA2981061A1 (en) | 2015-03-31 | 2016-10-06 | Cartiva, Inc. | Hydrogel implants with porous materials and methods |
EP3892241A1 (de) | 2015-03-31 | 2021-10-13 | Cartiva, Inc. | Bohrer für karpometakarpalimplantat |
CA2981074C (en) | 2015-04-14 | 2023-03-28 | Cartiva, Inc. | Tooling for creating tapered opening in tissue and related methods |
US11077228B2 (en) | 2015-08-10 | 2021-08-03 | Hyalex Orthopaedics, Inc. | Interpenetrating polymer networks |
US10058393B2 (en) | 2015-10-21 | 2018-08-28 | P Tech, Llc | Systems and methods for navigation and visualization |
EP3655474B1 (de) * | 2017-07-20 | 2023-05-24 | Sika Technology AG | Hydrogele mit verbesserter mechanischer festigkeit |
US10869950B2 (en) | 2018-07-17 | 2020-12-22 | Hyalex Orthopaedics, Inc. | Ionic polymer compositions |
US11628466B2 (en) | 2018-11-29 | 2023-04-18 | Surmodics, Inc. | Apparatus and methods for coating medical devices |
US11819590B2 (en) | 2019-05-13 | 2023-11-21 | Surmodics, Inc. | Apparatus and methods for coating medical devices |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3274519D1 (en) * | 1981-07-30 | 1987-01-15 | Ceraver | Prosthetic stem composed of titanium or its alloys for the cementless fixation in a long bone |
ATE18675T1 (de) * | 1982-11-30 | 1986-04-15 | Lrc Products | Verfahren zur beschichtung von gegenstaenden aus gummi oder kunststoff. |
US4527293A (en) * | 1983-05-18 | 1985-07-09 | University Of Miami | Hydrogel surface of urological prosthesis |
US4487865A (en) * | 1983-12-15 | 1984-12-11 | Biomatrix, Inc. | Polymeric articles modified with hyaluronate |
FR2649404B1 (fr) * | 1984-08-23 | 1994-05-20 | Universal High Technologies | Procede de revetement hydrophile de matieres plastiques et ses applications medicales |
DE3445738A1 (de) * | 1984-12-14 | 1986-06-19 | Draenert Klaus | Implantat zur knochenverstaerkung und verankerung von knochenschrauben, implantaten oder implantatteilen |
DE3533369A1 (de) * | 1985-09-19 | 1987-03-19 | Alois Prof Dr Med Bloemer | Antibioticahaltiges mittel und seine verwendung als chirurgisches kunststoffmaterial |
IT1198449B (it) * | 1986-10-13 | 1988-12-21 | F I D I Farmaceutici Italiani | Esteri di alcoli polivalenti di acido ialuronico |
IT1198162B (it) * | 1986-11-25 | 1988-12-21 | Luigi Ambrosio | Protesi ortopedica per la riduzione di fratture ossee,materiale per la sua fabbricazione e procedimenti per ottenerli |
US5290558A (en) * | 1989-09-21 | 1994-03-01 | Osteotech, Inc. | Flowable demineralized bone powder composition and its use in bone repair |
US5329846A (en) * | 1991-08-12 | 1994-07-19 | Bonutti Peter M | Tissue press and system |
-
1992
- 1992-05-20 IT ITPD920088A patent/IT1259100B/it active IP Right Grant
-
1993
- 1993-05-21 EP EP93912762A patent/EP0642363B1/de not_active Expired - Lifetime
- 1993-05-21 DE DE69330879T patent/DE69330879T2/de not_active Expired - Lifetime
- 1993-05-21 AT AT93912762T patent/ATE206316T1/de active
- 1993-05-21 US US08/341,541 patent/US5645592A/en not_active Expired - Lifetime
- 1993-05-21 WO PCT/EP1993/001288 patent/WO1993023094A1/en active IP Right Grant
Also Published As
Publication number | Publication date |
---|---|
US5645592A (en) | 1997-07-08 |
ITPD920088A1 (it) | 1993-11-20 |
EP0642363A1 (de) | 1995-03-15 |
IT1259100B (it) | 1996-03-11 |
WO1993023094A1 (en) | 1993-11-25 |
ATE206316T1 (de) | 2001-10-15 |
ITPD920088A0 (it) | 1992-05-20 |
EP0642363B1 (de) | 2001-10-04 |
DE69330879D1 (de) | 2001-11-08 |
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