DE69030581D1 - Verfahren zur untersuchung von gegeständen makromolekularer grösse - Google Patents

Verfahren zur untersuchung von gegeständen makromolekularer grösse

Info

Publication number
DE69030581D1
DE69030581D1 DE69030581T DE69030581T DE69030581D1 DE 69030581 D1 DE69030581 D1 DE 69030581D1 DE 69030581 T DE69030581 T DE 69030581T DE 69030581 T DE69030581 T DE 69030581T DE 69030581 D1 DE69030581 D1 DE 69030581D1
Authority
DE
Germany
Prior art keywords
sample
pct
date
discontinuity
sec
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69030581T
Other languages
English (en)
Other versions
DE69030581T2 (de
Inventor
Robert Jeffrey Geddes Carr
Anthony Atkinson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CARR ROBERT JEFFREY
Original Assignee
CARR ROBERT JEFFREY
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by CARR ROBERT JEFFREY filed Critical CARR ROBERT JEFFREY
Application granted granted Critical
Publication of DE69030581D1 publication Critical patent/DE69030581D1/de
Publication of DE69030581T2 publication Critical patent/DE69030581T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/0004—Microscopes specially adapted for specific applications
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Electro-optical investigation, e.g. flow cytometers
    • G01N15/1434—Electro-optical investigation, e.g. flow cytometers using an analyser being characterised by its optical arrangement
DE69030581T 1989-09-12 1990-09-12 Verfahren zur untersuchung von gegeständen makromolekularer grösse Expired - Fee Related DE69030581T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB898920571A GB8920571D0 (en) 1989-09-12 1989-09-12 Examination of objects of macromolecular size
PCT/GB1990/001407 WO1991004507A1 (en) 1989-09-12 1990-09-12 Examination of objects of macromolecular size

Publications (2)

Publication Number Publication Date
DE69030581D1 true DE69030581D1 (de) 1997-05-28
DE69030581T2 DE69030581T2 (de) 1997-09-11

Family

ID=10662917

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69030581T Expired - Fee Related DE69030581T2 (de) 1989-09-12 1990-09-12 Verfahren zur untersuchung von gegeständen makromolekularer grösse

Country Status (8)

Country Link
US (1) US5362653A (de)
EP (1) EP0497788B1 (de)
AT (1) ATE152250T1 (de)
AU (1) AU6431090A (de)
DE (1) DE69030581T2 (de)
GB (1) GB8920571D0 (de)
WO (1) WO1991004507A1 (de)
ZA (1) ZA907284B (de)

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JPH05500715A (ja) * 1989-10-04 1993-02-12 イー・アイ・デユポン・ドウ・ヌムール・アンド・カンパニー バイオセンサーの表面上の生物学的標的複合体のアツセイ方法
DE4438391C2 (de) * 1994-10-27 1997-07-03 Evotec Biosystems Gmbh Vorrichtung zur Bestimmung stoffspezifischer Parameter eines oder weniger Moleküle mittels Korrelations-Spektroskopie
EP0732584A3 (de) * 1995-03-16 1999-06-30 International Business Machines Corporation Verfahren und Aufbau zur Identifizierung einer Codesequenz eines Biomoleküls
US5538898A (en) * 1995-03-16 1996-07-23 International Business Machines Corporation Method suitable for identifying a code sequence of a biomolecule
US7041510B2 (en) 1996-04-25 2006-05-09 Bioarray Solutions Ltd. System and method for programmable illumination pattern generation
US6958245B2 (en) 1996-04-25 2005-10-25 Bioarray Solutions Ltd. Array cytometry
US7144119B2 (en) * 1996-04-25 2006-12-05 Bioarray Solutions Ltd. System and method for programmable illumination pattern generation
ATE366418T1 (de) * 1996-04-25 2007-07-15 Bioarray Solutions Ltd Licht-regulierte, elektrokinetische zusammensetzung von partikeln an oberflächen
US6387707B1 (en) * 1996-04-25 2002-05-14 Bioarray Solutions Array Cytometry
DE69825601T2 (de) 1997-02-12 2005-04-28 Chan, Eugene Y, Brookline Verfahren zur analyse von polymeren
US20030027126A1 (en) 1997-03-14 2003-02-06 Walt David R. Methods for detecting target analytes and enzymatic reactions
US7622294B2 (en) 1997-03-14 2009-11-24 Trustees Of Tufts College Methods for detecting target analytes and enzymatic reactions
CA2291853C (en) * 1997-05-23 2013-01-15 Bioarray Solutions Llc Color-encoding and in-situ interrogation of matrix-coupled chemical compounds
GB2326229A (en) 1997-06-13 1998-12-16 Robert Jeffrey Geddes Carr Detecting and analysing submicron particles
GB2380792B (en) * 1998-05-16 2003-07-23 Microbial Systems Ltd Particle detection system and components thereof
GB9810492D0 (en) * 1998-05-16 1998-07-15 Microbial Systems Ltd Particle detection system and components thereof
WO2001069202A2 (en) * 2000-03-16 2001-09-20 Ulrik Darling Larsen Sensor units for particle characterisation apparatus
US9709559B2 (en) 2000-06-21 2017-07-18 Bioarray Solutions, Ltd. Multianalyte molecular analysis using application-specific random particle arrays
US7892854B2 (en) 2000-06-21 2011-02-22 Bioarray Solutions, Ltd. Multianalyte molecular analysis using application-specific random particle arrays
US7057704B2 (en) * 2000-09-17 2006-06-06 Bioarray Solutions Ltd. System and method for programmable illumination pattern generation
US20030045005A1 (en) * 2000-10-17 2003-03-06 Michael Seul Light-controlled electrokinetic assembly of particles near surfaces
US7211414B2 (en) 2000-12-01 2007-05-01 Visigen Biotechnologies, Inc. Enzymatic nucleic acid synthesis: compositions and methods for altering monomer incorporation fidelity
US7262063B2 (en) 2001-06-21 2007-08-28 Bio Array Solutions, Ltd. Directed assembly of functional heterostructures
CN100494395C (zh) 2001-10-15 2009-06-03 生物芯片技术有限公司 通过同时探查和酶介导检测的多态性基因座多重分析
WO2004047007A1 (en) 2002-11-15 2004-06-03 Bioarray Solutions, Ltd. Analysis, secure access to, and transmission of array images
US6985223B2 (en) * 2003-03-07 2006-01-10 Purdue Research Foundation Raman imaging and sensing apparatus employing nanoantennas
US7927796B2 (en) 2003-09-18 2011-04-19 Bioarray Solutions, Ltd. Number coding for identification of subtypes of coded types of solid phase carriers
EP1664722B1 (de) 2003-09-22 2011-11-02 Bioarray Solutions Ltd Oberflächenimmobilisierter polyelektrolyt mit mehreren, zur kovalenten bindung an biomoleküle fähigen funktionellen gruppen
EP1692298A4 (de) 2003-10-28 2008-08-13 Bioarray Solutions Ltd Optimierung der genexpressionsanalyse unter verwendung immobilisierter fängersonden
PT1694859E (pt) 2003-10-29 2015-04-13 Bioarray Solutions Ltd Análise de ácidos nucleicos multiplexada através de fragmentação de adn de cadeia dupla
US7773227B2 (en) * 2004-06-04 2010-08-10 California Institute Of Technology Optofluidic microscope device featuring a body comprising a fluid channel and having light transmissive regions
US7751048B2 (en) * 2004-06-04 2010-07-06 California Institute Of Technology Optofluidic microscope device
US7848889B2 (en) 2004-08-02 2010-12-07 Bioarray Solutions, Ltd. Automated analysis of multiplexed probe-target interaction patterns: pattern matching and allele identification
US8486629B2 (en) 2005-06-01 2013-07-16 Bioarray Solutions, Ltd. Creation of functionalized microparticle libraries by oligonucleotide ligation or elongation
US7768654B2 (en) 2006-05-02 2010-08-03 California Institute Of Technology On-chip phase microscope/beam profiler based on differential interference contrast and/or surface plasmon assisted interference
US9041938B2 (en) 2006-05-02 2015-05-26 California Institute Of Technology Surface wave assisted structures and systems
US20080048669A1 (en) * 2006-08-28 2008-02-28 Dzulkifli Saul Scherber Topological mapping using a conductive infrastructure
US7375808B2 (en) * 2006-09-28 2008-05-20 The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration Method and system for sensing and identifying foreign particles in a gaseous environment
US8325349B2 (en) * 2008-03-04 2012-12-04 California Institute Of Technology Focal plane adjustment by back propagation in optofluidic microscope devices
WO2009111573A2 (en) * 2008-03-04 2009-09-11 California Institute Of Technology Optofluidic microscope device with photosensor array
EP2250485A1 (de) * 2008-03-04 2010-11-17 California Institute of Technology Verfahren zur verwendung optofluidischer mikroskope
US8039776B2 (en) 2008-05-05 2011-10-18 California Institute Of Technology Quantitative differential interference contrast (DIC) microscopy and photography based on wavefront sensors
CN102292662A (zh) * 2009-01-21 2011-12-21 加州理工学院 用于计算深度切片的定量微分干涉差（dic）设备
US8416400B2 (en) * 2009-06-03 2013-04-09 California Institute Of Technology Wavefront imaging sensor
US8633432B2 (en) * 2009-09-21 2014-01-21 California Institute Of Technology Reflective focusing and transmissive projection device
WO2011119678A2 (en) * 2010-03-23 2011-09-29 California Institute Of Technology Super resolution optofluidic microscopes for 2d and 3d imaging
WO2012033957A2 (en) 2010-09-09 2012-03-15 California Institute Of Technology Delayed emission detection devices and methods
CN102169082B (zh) * 2010-12-31 2012-07-04 中国水电顾问集团中南勘测设计研究院 一种渗透变形测试仪
US8343771B2 (en) 2011-01-12 2013-01-01 General Electric Company Methods of using cyanine dyes for the detection of analytes
DE102015218422A1 (de) 2015-09-24 2017-03-30 Universität Stuttgart Sensorelement für Photolumineszenz-Messungen, Photolumineszenz-Detektionseinrichtung, Verfahren zum Betreiben einer Photolumineszenz-Detektionseinrichtung, Verfahren zur Herstellung eines Sensorelements, und Verwendung eines Sensorelements
US10598594B2 (en) 2015-12-22 2020-03-24 University Of Maryland Cell classification based on mechanical signature of nucleus
US10732092B2 (en) 2015-12-22 2020-08-04 University Of Maryland, College Park Analysis of single cell mechanical phenotyping for metastatic detection
JP7138050B2 (ja) 2015-12-22 2022-09-15 キヤノン ユー．エス． ライフ サイエンシズ， インコーポレイテッド ブリルアン光散乱に基づくラベルフリーサイトメトリーのシステム及び方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4420720A (en) * 1981-06-29 1983-12-13 Coulter Electronics, Inc. Field focused particle sensing zone
US4778657A (en) * 1985-09-10 1988-10-18 Kernforschungszentrum Karlsruhe Gmbh Apparatus for determining the characteristics of particles suspended in liquids
US4760328A (en) * 1986-05-05 1988-07-26 Integrated Ionics, Inc. Particle counter having electrodes and circuitry mounted on the pane of the orifice
DE3772563D1 (de) * 1987-06-22 1991-10-02 Ibm Verfahren zur oberflaechenuntersuchung mit nanometer- und pikosekundenaufloesung sowie laserabgetastetes rastertunnelmikroskop zur durchfuehrung des verfahrens.
DE3772573D1 (de) * 1987-09-25 1991-10-02 Ibm Sensor zur umsetzung eines abstandes in optische und weiterhin in elektrische energie

Also Published As

Publication number Publication date
US5362653A (en) 1994-11-08
GB8920571D0 (en) 1989-10-25
DE69030581T2 (de) 1997-09-11
WO1991004507A1 (en) 1991-04-04
ATE152250T1 (de) 1997-05-15
ZA907284B (en) 1991-07-31
EP0497788A1 (de) 1992-08-12
AU6431090A (en) 1991-04-18
EP0497788B1 (de) 1997-04-23

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8339 Ceased/non-payment of the annual fee