DE69027121T2 - Bindeligande für tumornekrosisfaktor - Google Patents

Bindeligande für tumornekrosisfaktor

Info

Publication number
DE69027121T2
DE69027121T2 DE69027121T DE69027121T DE69027121T2 DE 69027121 T2 DE69027121 T2 DE 69027121T2 DE 69027121 T DE69027121 T DE 69027121T DE 69027121 T DE69027121 T DE 69027121T DE 69027121 T2 DE69027121 T2 DE 69027121T2
Authority
DE
Germany
Prior art keywords
tumorncrosis
landing
binding
factor
tumorncrosis factor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69027121T
Other languages
English (en)
Other versions
DE69027121T3 (de
DE69027121D1 (de
Inventor
Deborah Rathjen
Roger Aston
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Teva Pharmaceuticals Australia Pty Ltd
Original Assignee
Peptide Technology Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25643730&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69027121(T2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Peptide Technology Ltd filed Critical Peptide Technology Ltd
Application granted granted Critical
Publication of DE69027121D1 publication Critical patent/DE69027121D1/de
Publication of DE69027121T2 publication Critical patent/DE69027121T2/de
Publication of DE69027121T3 publication Critical patent/DE69027121T3/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/241—Tumor Necrosis Factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
    • A61K47/6801—Drug-antibody or immunoglobulin conjugates defined by the pharmacologically or therapeutically active agent
    • A61K47/6803—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates
    • A61K47/6811—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates the drug being a protein or peptide, e.g. transferrin or bleomycin
    • A61K47/6813—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates the drug being a protein or peptide, e.g. transferrin or bleomycin the drug being a peptidic cytokine, e.g. an interleukin or interferon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
DE69027121T 1989-08-07 1990-08-07 Bindeligande für tumornekrosisfaktor Expired - Lifetime DE69027121T3 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
AUPJ566289 1989-08-07
AUPJ757689 1989-11-24
PCT/AU1990/000337 WO1991002078A1 (en) 1989-08-07 1990-08-07 Tumour necrosis factor binding ligands

Publications (3)

Publication Number Publication Date
DE69027121D1 DE69027121D1 (de) 1996-06-27
DE69027121T2 true DE69027121T2 (de) 1996-11-14
DE69027121T3 DE69027121T3 (de) 2001-08-30

Family

ID=25643730

Family Applications (2)

Application Number Title Priority Date Filing Date
DE69027121T Expired - Lifetime DE69027121T3 (de) 1989-08-07 1990-08-07 Bindeligande für tumornekrosisfaktor
DE2003199036 Pending DE10399036I1 (de) 1989-08-07 1990-08-07 Bindeligande für Tumornekrosisfaktor.

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE2003199036 Pending DE10399036I1 (de) 1989-08-07 1990-08-07 Bindeligande für Tumornekrosisfaktor.

Country Status (8)

Country Link
US (2) US7605233B2 (de)
EP (1) EP0486526B2 (de)
JP (7) JP3443119B2 (de)
AU (1) AU640400B2 (de)
CA (1) CA2064915C (de)
DE (2) DE69027121T3 (de)
DK (1) DK0486526T3 (de)
WO (1) WO1991002078A1 (de)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2005220156B2 (en) * 2004-02-27 2011-06-02 Vaxconsulting Peptides of IL1 beta and TNF alpha and method of treatment using same

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* Cited by examiner, † Cited by third party
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JP4469013B2 (ja) 2010-05-26
JP2006089503A (ja) 2006-04-06
JP3717466B2 (ja) 2005-11-16
JP3977395B2 (ja) 2007-09-19
JPH04507195A (ja) 1992-12-17
CA2064915C (en) 2001-05-29
US20100125130A1 (en) 2010-05-20
DK0486526T3 (da) 1996-06-24
EP0486526A4 (en) 1993-05-05
JP2003231699A (ja) 2003-08-19
DE10399036I1 (de) 2004-04-01
JP2007197458A (ja) 2007-08-09
WO1991002078A1 (en) 1991-02-21
JP2003096096A (ja) 2003-04-03
EP0486526A1 (de) 1992-05-27
CA2064915A1 (en) 1991-02-08
JP2009114218A (ja) 2009-05-28
DE69027121T3 (de) 2001-08-30
EP0486526B1 (de) 1996-05-22
US7605233B2 (en) 2009-10-20
AU640400B2 (en) 1993-08-26
DE69027121D1 (de) 1996-06-27
AU6145490A (en) 1991-03-11

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