DE68927161T2 - Zellulosebindende fusionsproteine - Google Patents
Zellulosebindende fusionsproteineInfo
- Publication number
- DE68927161T2 DE68927161T2 DE68927161T DE68927161T DE68927161T2 DE 68927161 T2 DE68927161 T2 DE 68927161T2 DE 68927161 T DE68927161 T DE 68927161T DE 68927161 T DE68927161 T DE 68927161T DE 68927161 T2 DE68927161 T2 DE 68927161T2
- Authority
- DE
- Germany
- Prior art keywords
- polypeptide
- cellulose
- binding region
- fusion protein
- affinity matrix
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08H—DERIVATIVES OF NATURAL MACROMOLECULAR COMPOUNDS
- C08H8/00—Macromolecular compounds derived from lignocellulosic materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
- C07K14/55—IL-2
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B15/00—Preparation of other cellulose derivatives or modified cellulose, e.g. complexes
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
- C08B37/0024—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid beta-D-Glucans; (beta-1,3)-D-Glucans, e.g. paramylon, coriolan, sclerotan, pachyman, callose, scleroglucan, schizophyllan, laminaran, lentinan or curdlan; (beta-1,6)-D-Glucans, e.g. pustulan; (beta-1,4)-D-Glucans; (beta-1,3)(beta-1,4)-D-Glucans, e.g. lichenan; Derivatives thereof
- C08B37/0027—2-Acetamido-2-deoxy-beta-glucans; Derivatives thereof
- C08B37/003—Chitin, i.e. 2-acetamido-2-deoxy-(beta-1,4)-D-glucan or N-acetyl-beta-1,4-D-glucosamine; Chitosan, i.e. deacetylated product of chitin or (beta-1,4)-D-glucosamine; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
- C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
- C12N11/10—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a carbohydrate
- C12N11/12—Cellulose or derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
- C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
- C12N9/2405—Glucanases
- C12N9/2434—Glucanases acting on beta-1,4-glucosidic bonds
- C12N9/2437—Cellulases (3.2.1.4; 3.2.1.74; 3.2.1.91; 3.2.1.150)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
- C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
- C12N9/2405—Glucanases
- C12N9/2434—Glucanases acting on beta-1,4-glucosidic bonds
- C12N9/2445—Beta-glucosidase (3.2.1.21)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
- C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
- C12N9/2468—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1) acting on beta-galactose-glycoside bonds, e.g. carrageenases (3.2.1.83; 3.2.1.157); beta-agarase (3.2.1.81)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/56—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving blood clotting factors, e.g. involving thrombin, thromboplastin, fibrinogen
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
- C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
- C12Y302/01004—Cellulase (3.2.1.4), i.e. endo-1,4-beta-glucanase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
- C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
- C12Y302/01021—Beta-glucosidase (3.2.1.21)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
- C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
- C12Y302/01091—Cellulose 1,4-beta-cellobiosidase (3.2.1.91)
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- D—TEXTILES; PAPER
- D21—PAPER-MAKING; PRODUCTION OF CELLULOSE
- D21H—PULP COMPOSITIONS; PREPARATION THEREOF NOT COVERED BY SUBCLASSES D21C OR D21D; IMPREGNATING OR COATING OF PAPER; TREATMENT OF FINISHED PAPER NOT COVERED BY CLASS B31 OR SUBCLASS D21G; PAPER NOT OTHERWISE PROVIDED FOR
- D21H17/00—Non-fibrous material added to the pulp, characterised by its constitution; Paper-impregnating material characterised by its constitution
- D21H17/005—Microorganisms or enzymes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/531—Production of immunochemical test materials
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/33—Fusion polypeptide fusions for targeting to specific cell types, e.g. tissue specific targeting, targeting of a bacterial subspecies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/50—Fusion polypeptide containing protease site
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/61—Fusion polypeptide containing an enzyme fusion for detection (lacZ, luciferase)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
- C07K2319/74—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
- C07K2319/75—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/803—Physical recovery methods, e.g. chromatography, grinding
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/808—Materials and products related to genetic engineering or hybrid or fused cell technology, e.g. hybridoma, monoclonal products
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/81—Carrier - bound or immobilized peptides or proteins and the preparation thereof, e.g. biological cell or cell fragment as carrier
- Y10S530/812—Peptides or proteins is immobilized on, or in, an organic carrier
- Y10S530/813—Carrier is a saccharide
- Y10S530/814—Cellulose or derivatives thereof
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/216,794 US5137819A (en) | 1988-07-08 | 1988-07-08 | Cellulose binding fusion proteins for immobilization and purification of polypeptides |
PCT/GB1989/000718 WO1990000609A1 (en) | 1988-07-08 | 1989-06-28 | Cellulose binding fusion proteins |
Publications (2)
Publication Number | Publication Date |
---|---|
DE68927161D1 DE68927161D1 (de) | 1996-10-17 |
DE68927161T2 true DE68927161T2 (de) | 1997-01-30 |
Family
ID=22808538
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE68927161T Expired - Lifetime DE68927161T2 (de) | 1988-07-08 | 1989-06-28 | Zellulosebindende fusionsproteine |
Country Status (7)
Country | Link |
---|---|
US (2) | US5137819A (de) |
EP (1) | EP0381719B1 (de) |
JP (1) | JP2528721B2 (de) |
AT (1) | ATE142699T1 (de) |
CA (1) | CA1335182C (de) |
DE (1) | DE68927161T2 (de) |
WO (1) | WO1990000609A1 (de) |
Families Citing this family (106)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6048715A (en) * | 1988-07-08 | 2000-04-11 | Univ. Of British Columbia | Two-phase partition affinity separation system and affinity separated cell-containing composition |
US5340731A (en) * | 1988-07-08 | 1994-08-23 | University Of British Columbia | Method of preparing a B-1,4 glycan matrix containing a bound fusion protein |
US6174700B1 (en) * | 1988-07-08 | 2001-01-16 | University Of British Columbia | Purification of a polypeptide compound having a polysaccharide binding domain by affinity phase separation |
US5595887A (en) * | 1990-07-16 | 1997-01-21 | Bionebraska, Inc. | Purification directed cloning of peptides using carbonic anhydrase as the affinity binding segment |
CA2069962A1 (en) * | 1990-08-17 | 1992-02-18 | Shi-Hsiang Shen | Recombinant dna production of beta-1, 3-glucanase |
US6512166B1 (en) | 1991-06-17 | 2003-01-28 | Cornell Research Foundation, Inc. | Combinations of fungal cell wall degrading enzyme and fungal cell membrane affecting compound |
US6020540A (en) * | 1993-04-14 | 2000-02-01 | Cornell Research Foundation, Inc. | Gene encoding endochitinase |
AU665599B2 (en) * | 1991-11-08 | 1996-01-11 | Hemosol Inc. | Hemoglobins as drug delivery agents |
US5872094A (en) * | 1993-01-06 | 1999-02-16 | The General Hospital Corporation | Method for attaching cartilaginous tissue, cartilage matrix protein or link protein to a surface |
US5496934A (en) * | 1993-04-14 | 1996-03-05 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Nucleic acids encoding a cellulose binding domain |
US6268196B1 (en) | 1993-12-17 | 2001-07-31 | Genencor International, Inc. | Method and compositions for treating cellulose containing fabrics using truncated cellulase enzyme compositions |
US7005128B1 (en) | 1993-12-17 | 2006-02-28 | Genencor International, Inc. | Enzyme feed additive and animal feed including it |
US5861271A (en) * | 1993-12-17 | 1999-01-19 | Fowler; Timothy | Cellulase enzymes and systems for their expressions |
GB9400623D0 (en) * | 1994-01-14 | 1994-03-09 | Univ Leeds | Exploitation of the cellulase enzyme complex of neurospora |
IL111415A0 (en) * | 1994-10-27 | 1994-12-29 | Yeda Res & Dev | Modified cellulose-binding domain (cbd) proteins and use thereof |
US6251951B1 (en) | 1994-12-30 | 2001-06-26 | Proguard, Inc | Use of flavonoid and aromatic aldehydes as pesticides |
US6750256B1 (en) * | 1994-12-30 | 2004-06-15 | Proguard, Inc. | Use of aromatic aldehydes as insecticides |
US5536501A (en) * | 1994-12-30 | 1996-07-16 | Proguard, Inc. | Use of flavenoid aldehydes as insecticides and for killing arachnids |
CN101173263A (zh) | 1995-03-17 | 2008-05-07 | 诺沃奇梅兹有限公司 | 新的内切葡聚糖酶 |
US5843375A (en) * | 1995-06-07 | 1998-12-01 | Proguard, Inc. | Method for decontamination of a liquid of gaseous environment |
US5792467A (en) * | 1995-06-07 | 1998-08-11 | Proguard, Inc. | Repellent compositions containing aromatic aldehydes |
US5639794A (en) * | 1995-06-07 | 1997-06-17 | Proguard, Inc. | Use of saponin in methods and compositions for pathogen control |
US5874308A (en) * | 1996-01-16 | 1999-02-23 | University Of British Columbia | Compositions and methods for modulating cell proliferation using growth factor-polysaccharide binding fusion proteins |
DE69730821T2 (de) * | 1996-01-29 | 2005-09-29 | Novozymes A/S | Verfahren zum entfernen oder bleichen von verschmutzungen oder flecken aus zellulosekaltigem gewebe |
CN1209838A (zh) * | 1996-01-29 | 1999-03-03 | 诺沃挪第克公司 | 纤维素织物的脱浆方法 |
AU2382197A (en) * | 1996-04-19 | 1997-11-12 | Novo Nordisk A/S | Fabric treated with a cellulase and a hybrid enzyme comprising a phenol oxidizing enzyme |
AU2381297A (en) * | 1996-04-19 | 1997-11-12 | Novo Nordisk A/S | Bleaching of fabric with a hybrid enzyme containing a phenol oxidizing enzyme fused to a cellulose binding domain |
GB9613758D0 (en) † | 1996-07-01 | 1996-09-04 | Unilever Plc | Detergent composition |
NZ334637A (en) * | 1996-09-30 | 2001-02-23 | Exseed Genetics L | Hybride polypeptides, their encapsulation within a modified starch and administration of the starch to animals |
JP4463878B2 (ja) * | 1996-10-28 | 2010-05-19 | ノボザイムス アクティーゼルスカブ | バチルス菌を用いたセルロース結合ドメインの細胞外発現 |
US20020168718A1 (en) * | 1997-04-03 | 2002-11-14 | California Institute Of Technology | Enzyme-mediated modification of fibrin for tissue engineering |
IL121404A0 (en) * | 1997-07-27 | 1998-01-04 | Yissum Res Dev Co | Transgenic higher plants of altered structural morphology |
GB9718415D0 (en) * | 1997-08-29 | 1997-11-05 | Smithkline Beecham Plc | Formulation |
TW552268B (en) | 1997-10-08 | 2003-09-11 | Yun-Ru Chen | Chimeric proteins with a cellulose binding domain (CBD) |
US6323023B1 (en) | 1998-01-13 | 2001-11-27 | Yissum Research Development Co., Ltd. | Vectors containing nucleic acids coding for Arabidopsis thaliana endo-1,4-β-glucanase secretion signal peptide |
EP1829551B1 (de) | 1998-02-20 | 2010-09-29 | University of Miami | Modifizierter Hitzeschockprotein-Antigenpeptid-Komplex |
US6315900B1 (en) | 1998-06-03 | 2001-11-13 | Accurate Polymers | Static separation method using non-porous cellulose beads |
CA2331199C (en) | 1998-06-10 | 2012-10-23 | Markus Sakari Kauppinen | Isolated mannanases for use in treating cellulosic or synthetic fibers |
US6894022B1 (en) | 1998-08-27 | 2005-05-17 | Eidgenossische Technische Hochschule Zurich | Growth factor modified protein matrices for tissue engineering |
US7601685B2 (en) * | 1998-08-27 | 2009-10-13 | Eidgenossische Technische Hochschule Zurich | Growth factor modified protein matrices for tissue engineering |
US7241730B2 (en) | 1998-08-27 | 2007-07-10 | Universitat Zurich | Enzyme-mediated modification of fibrin for tissue engineering: fibrin formulations with peptides |
AU776069B2 (en) * | 1999-11-08 | 2004-08-26 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Process and composition for preparing a lignocellulose-based product, and the product obtained by the process |
IL133134A0 (en) * | 1999-11-25 | 2001-03-19 | American Israeli Paper Mills | Improved paper products |
KR101105984B1 (ko) | 2001-01-19 | 2012-01-18 | 비로노바티브 비.브이. | 감응성 포유류에서 호흡계 질환을 유발하는 바이러스 |
JP4242761B2 (ja) | 2001-06-06 | 2009-03-25 | ノボザイムス アクティーゼルスカブ | エンド−β−1,4−グルカナーゼ |
GR20010100295A (el) | 2001-06-18 | 2003-02-27 | Εμμανουηλ Παττακος | Μεταβλητο συστημα βαλβιδων |
IL160641A0 (en) * | 2001-10-03 | 2004-07-25 | Unilever Plc | Carbohydrate binding domain containing fusion proteins for delivery of therapeutic and other agents, and compositions containing them |
US7247609B2 (en) * | 2001-12-18 | 2007-07-24 | Universitat Zurich | Growth factor modified protein matrices for tissue engineering |
CA2477234C (en) | 2002-02-21 | 2014-12-30 | Medimmune Vaccines, Inc. | Metapneumovirus strains and their use in vaccine formulations and as vectors for expression of antigenic sequences |
EP1565744A4 (de) * | 2002-03-07 | 2007-06-20 | Zephyr Proteomix Ltd | Mikroarrays zellulosebindender chimärer proteine und verfahren zur verwendung davon |
US20060035342A1 (en) * | 2002-09-12 | 2006-02-16 | Withers Stephen G | Engineered enzymes and their use for synthesis of thioglycosides |
AU2003267356A1 (en) * | 2002-10-01 | 2004-04-23 | Unilever Plc | Proteins having polysaccharidase activity |
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DE3410437A1 (de) * | 1984-03-22 | 1985-09-26 | Bayer Ag, 5090 Leverkusen | Verfahren zur herstellung von proteinen |
JPS61264000A (ja) * | 1985-03-21 | 1986-11-21 | イミユネツクス コ−ポレイシヨン | 標識ペプチドによるタンパク質の合成 |
US4745055A (en) * | 1985-05-07 | 1988-05-17 | California Biotechnology Inc. | Fused protein for enzyme immunoassay system |
EP0244147A3 (de) * | 1986-04-28 | 1989-04-05 | Merck & Co. Inc. | Verfahren zur Reinigung hybrider Proteine |
DE286239T1 (de) * | 1987-03-10 | 1994-02-24 | New England Biolabs Inc | Herstellung und Reinigung eines Proteins, das mit einem Bindungsprotein fusioniert ist. |
-
1988
- 1988-07-08 US US07/216,794 patent/US5137819A/en not_active Expired - Lifetime
-
1989
- 1989-06-22 CA CA000603567A patent/CA1335182C/en not_active Expired - Lifetime
- 1989-06-28 JP JP1507496A patent/JP2528721B2/ja not_active Expired - Fee Related
- 1989-06-28 DE DE68927161T patent/DE68927161T2/de not_active Expired - Lifetime
- 1989-06-28 AT AT89907798T patent/ATE142699T1/de not_active IP Right Cessation
- 1989-06-28 EP EP89907798A patent/EP0381719B1/de not_active Expired - Lifetime
- 1989-06-28 WO PCT/GB1989/000718 patent/WO1990000609A1/en active IP Right Grant
-
1990
- 1990-10-25 US US07/603,987 patent/US5202247A/en not_active Expired - Lifetime
Also Published As
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---|---|
JP2528721B2 (ja) | 1996-08-28 |
DE68927161D1 (de) | 1996-10-17 |
WO1990000609A1 (en) | 1990-01-25 |
EP0381719A1 (de) | 1990-08-16 |
ATE142699T1 (de) | 1996-09-15 |
EP0381719B1 (de) | 1996-09-11 |
CA1335182C (en) | 1995-04-11 |
US5202247A (en) | 1993-04-13 |
JPH03501261A (ja) | 1991-03-22 |
US5137819A (en) | 1992-08-11 |
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