DE68905557T2 - Kontinuierliches beschallungsverfahren zur herstellung proteinverkapselter mikroblaeschen. - Google Patents

Kontinuierliches beschallungsverfahren zur herstellung proteinverkapselter mikroblaeschen.

Info

Publication number
DE68905557T2
DE68905557T2 DE8989116982T DE68905557T DE68905557T2 DE 68905557 T2 DE68905557 T2 DE 68905557T2 DE 8989116982 T DE8989116982 T DE 8989116982T DE 68905557 T DE68905557 T DE 68905557T DE 68905557 T2 DE68905557 T2 DE 68905557T2
Authority
DE
Germany
Prior art keywords
solution
protein
encapsed
microbottles
producing protein
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE8989116982T
Other languages
English (en)
Other versions
DE68905557D1 (de
Inventor
David Cerny
Gary J Mills
Peter J Westkaemper
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Molecular Biosystems Inc
Original Assignee
Molecular Biosystems Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Molecular Biosystems Inc filed Critical Molecular Biosystems Inc
Application granted granted Critical
Publication of DE68905557D1 publication Critical patent/DE68905557D1/de
Publication of DE68905557T2 publication Critical patent/DE68905557T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02—Making microcapsules or microballoons
    • B01J13/04—Making microcapsules or microballoons by physical processes, e.g. drying, spraying
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/22—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations
    • A61K49/222—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
    • A61K49/223—Microbubbles, hollow microspheres, free gas bubbles, gas microspheres
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
DE8989116982T 1988-09-14 1989-09-13 Kontinuierliches beschallungsverfahren zur herstellung proteinverkapselter mikroblaeschen. Expired - Lifetime DE68905557T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/244,844 US4957656A (en) 1988-09-14 1988-09-14 Continuous sonication method for preparing protein encapsulated microbubbles

Publications (2)

Publication Number Publication Date
DE68905557D1 DE68905557D1 (de) 1993-04-29
DE68905557T2 true DE68905557T2 (de) 1993-07-01

Family

ID=22924352

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8989116982T Expired - Lifetime DE68905557T2 (de) 1988-09-14 1989-09-13 Kontinuierliches beschallungsverfahren zur herstellung proteinverkapselter mikroblaeschen.

Country Status (15)

Country Link
US (1) US4957656A (de)
EP (1) EP0359246B1 (de)
JP (1) JPH0720545B2 (de)
KR (1) KR0135754B1 (de)
AT (1) ATE87217T1 (de)
AU (1) AU617215B2 (de)
CA (1) CA1337286C (de)
DE (1) DE68905557T2 (de)
DK (1) DK175484B1 (de)
ES (1) ES2054964T3 (de)
FI (1) FI95872C (de)
GR (1) GR3007483T3 (de)
IE (1) IE62602B1 (de)
IL (1) IL91593A0 (de)
NO (1) NO176871C (de)

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DK175484B1 (da) 2004-11-08
JPH0720545B2 (ja) 1995-03-08
EP0359246A3 (de) 1991-08-28
FI894335A (fi) 1990-03-15
DK451189A (da) 1990-03-15
NO176871C (no) 1995-06-14
NO893671D0 (no) 1989-09-13
EP0359246B1 (de) 1993-03-24
KR900004395A (ko) 1990-04-12
ATE87217T1 (de) 1993-04-15
CA1337286C (en) 1995-10-10
JPH02115037A (ja) 1990-04-27
IE62602B1 (en) 1995-02-22
ES2054964T3 (es) 1994-08-16
DK451189D0 (da) 1989-09-13
FI95872B (fi) 1995-12-29
FI95872C (fi) 1996-04-10
IL91593A0 (en) 1990-04-29
NO176871B (no) 1995-03-06
US4957656A (en) 1990-09-18
KR0135754B1 (ko) 1998-04-22
EP0359246A2 (de) 1990-03-21
FI894335A0 (fi) 1989-09-13
NO893671L (no) 1990-03-15
GR3007483T3 (de) 1993-07-30
AU617215B2 (en) 1991-11-21
IE892837L (en) 1990-03-14
AU4131289A (en) 1990-03-22
DE68905557D1 (de) 1993-04-29

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