DE60208231D1 - Robotersystem mit mehreren positionsverstellbaren pipetten - Google Patents

Robotersystem mit mehreren positionsverstellbaren pipetten

Info

Publication number
DE60208231D1
DE60208231D1 DE60208231T DE60208231T DE60208231D1 DE 60208231 D1 DE60208231 D1 DE 60208231D1 DE 60208231 T DE60208231 T DE 60208231T DE 60208231 T DE60208231 T DE 60208231T DE 60208231 D1 DE60208231 D1 DE 60208231D1
Authority
DE
Germany
Prior art keywords
probes
substrate surface
robot system
multiple position
position adjustable
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60208231T
Other languages
English (en)
Other versions
DE60208231T2 (de
Inventor
H Stokes
R Londo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Applied Biosystems LLC
Original Assignee
PerSeptive Biosystems Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by PerSeptive Biosystems Inc filed Critical PerSeptive Biosystems Inc
Application granted granted Critical
Publication of DE60208231D1 publication Critical patent/DE60208231D1/de
Publication of DE60208231T2 publication Critical patent/DE60208231T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L9/00—Supporting devices; Holding devices
    • B01L9/54—Supports specially adapted for pipettes and burettes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/0046—Sequential or parallel reactions, e.g. for the synthesis of polypeptides or polynucleotides; Apparatus and devices for combinatorial chemistry or for making molecular arrays
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1065—Multiple transfer devices
    • G01N35/1067—Multiple transfer devices for transfer to or from containers having different spacing
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00351—Means for dispensing and evacuation of reagents
    • B01J2219/00364—Pipettes
    • B01J2219/00367—Pipettes capillary
    • B01J2219/00369—Pipettes capillary in multiple or parallel arrangements
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00497—Features relating to the solid phase supports
    • B01J2219/00527—Sheets
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00585—Parallel processes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00596—Solid-phase processes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00603—Making arrays on substantially continuous surfaces
    • B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00603—Making arrays on substantially continuous surfaces
    • B01J2219/00659—Two-dimensional arrays
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/0068—Means for controlling the apparatus of the process
    • B01J2219/00686—Automatic
    • B01J2219/00691—Automatic using robots
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/14—Process control and prevention of errors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1065—Multiple transfer devices
    • G01N35/1067—Multiple transfer devices for transfer to or from containers having different spacing
    • G01N2035/1069—Multiple transfer devices for transfer to or from containers having different spacing by adjusting the spacing between multiple probes of a single transferring head
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1065—Multiple transfer devices
    • G01N2035/1076—Multiple transfer devices plurality or independently movable heads
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1065—Multiple transfer devices
    • G01N35/1074—Multiple transfer devices arranged in a two-dimensional array
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/2575—Volumetric liquid transfer
DE60208231T 2001-10-26 2002-09-25 Robotersystem mit mehreren positionsverstellbaren pipetten Expired - Lifetime DE60208231T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10/045,518 US6672344B1 (en) 2001-10-26 2001-10-26 Robotic system having positionally adjustable multiple probes
US45518 2001-10-26
PCT/US2002/030579 WO2003037515A1 (en) 2001-10-26 2002-09-25 Robotic system having positionally adjustable multiple probes

Publications (2)

Publication Number Publication Date
DE60208231D1 true DE60208231D1 (de) 2006-01-26
DE60208231T2 DE60208231T2 (de) 2006-08-10

Family

ID=21938354

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60208231T Expired - Lifetime DE60208231T2 (de) 2001-10-26 2002-09-25 Robotersystem mit mehreren positionsverstellbaren pipetten

Country Status (6)

Country Link
US (1) US6672344B1 (de)
EP (1) EP1444043B1 (de)
JP (1) JP4223401B2 (de)
AT (1) ATE313380T1 (de)
DE (1) DE60208231T2 (de)
WO (1) WO2003037515A1 (de)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7160511B2 (en) * 2000-02-18 2007-01-09 Olympus Corporation Liquid pipetting apparatus and micro array manufacturing apparatus
US7452712B2 (en) 2002-07-30 2008-11-18 Applied Biosystems Inc. Sample block apparatus and method of maintaining a microcard on a sample block
US6970240B2 (en) * 2003-03-10 2005-11-29 Applera Corporation Combination reader
US20050226779A1 (en) 2003-09-19 2005-10-13 Oldham Mark F Vacuum assist for a microplate
US20050221358A1 (en) * 2003-09-19 2005-10-06 Carrillo Albert L Pressure chamber clamp mechanism
US20050226771A1 (en) * 2003-09-19 2005-10-13 Lehto Dennis A High speed microplate transfer
US20070015289A1 (en) * 2003-09-19 2007-01-18 Kao H P Dispenser array spotting
US20050233472A1 (en) * 2003-09-19 2005-10-20 Kao H P Spotting high density plate using a banded format
JP2005098766A (ja) * 2003-09-24 2005-04-14 Shimadzu Corp 分画装置
US7628184B2 (en) * 2003-11-07 2009-12-08 Medical Instill Technologies, Inc. Adjustable needle filling and laser sealing apparatus and method
CN100489522C (zh) * 2004-08-30 2009-05-20 株式会社岛津制作所 试料前处理装置及其所使用的探头
EP1853906A4 (de) * 2005-02-08 2010-03-17 Mds Inc Dbt Mds Sciex Division Verfahren und vorrichtung zur probenablage
US7622079B2 (en) * 2005-03-22 2009-11-24 Applied Biosystems, Llc Dual nest microplate spotter
US8313711B2 (en) * 2005-11-01 2012-11-20 Freeslate, Inc. Liquid dispensing for high-throughput experimentation
WO2008076194A2 (en) 2006-11-13 2008-06-26 Raytheon Sarcos Llc Serpentine robotic crawler
DE602007013793D1 (de) 2006-11-13 2011-05-19 Raytheon Co Anpassbare spuranordnung für einen raupenroboter
WO2008076193A2 (en) 2006-11-13 2008-06-26 Raytheon Sarcos Llc Tracked robotic crawler having a moveable arm
DE602007007807D1 (de) 2006-11-13 2010-08-26 Raytheon Sarcos Llc Vielseitig verwendbares endlosband für leichte mobile roboter
EP2144659A1 (de) 2007-05-07 2010-01-20 Raytheon Sarcos, LLC Verfahren zur herstellung einer komplexen struktur
US8571711B2 (en) 2007-07-10 2013-10-29 Raytheon Company Modular robotic crawler
US8392036B2 (en) 2009-01-08 2013-03-05 Raytheon Company Point and go navigation system and method
EP2440448B1 (de) 2009-06-11 2015-09-30 Sarcos LC Amphibischer raupenroboter
WO2010144813A1 (en) 2009-06-11 2010-12-16 Raytheon Sarcos, Llc Method and system for deploying a surveillance network
US8550130B2 (en) * 2010-11-10 2013-10-08 Martin John Burrows Apparatus and method for refilling reusable containers
WO2013049071A1 (en) * 2011-09-26 2013-04-04 Integenx Inc. Methods and apparatuses for releasably fastening pins
KR101338884B1 (ko) 2011-10-06 2013-12-09 참엔지니어링(주) 카트리지 및 그 구동 장치 및 방법
US8393422B1 (en) 2012-05-25 2013-03-12 Raytheon Company Serpentine robotic crawler
US9031698B2 (en) 2012-10-31 2015-05-12 Sarcos Lc Serpentine robotic crawler
US9409292B2 (en) 2013-09-13 2016-08-09 Sarcos Lc Serpentine robotic crawler for performing dexterous operations
US9566711B2 (en) 2014-03-04 2017-02-14 Sarcos Lc Coordinated robotic control
US10210410B2 (en) 2014-10-22 2019-02-19 Integenx Inc. Systems and methods for biometric data collections
CN110215944B (zh) * 2019-07-08 2022-06-21 江苏汇先医药技术有限公司 一种自动移液枪
WO2021102043A1 (en) * 2019-11-21 2021-05-27 10X Genomics, Inc. Automated library generator
US11857981B2 (en) 2019-12-23 2024-01-02 10X Genomics, Inc. Magnetic separator for an automated single cell sequencing system

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3444742A (en) * 1965-12-06 1969-05-20 Univ Of Kentucky Research Foun Multiple-unit pipetting assembly and pipette for use therein
DE3410508C2 (de) * 1984-03-22 1986-06-26 Kernforschungsanlage Jülich GmbH, 5170 Jülich Serien-Abfüllgerät zum Befüllen der Becher einer Mikrobecherplatte
US4586546A (en) * 1984-10-23 1986-05-06 Cetus Corporation Liquid handling device and method
CH671526A5 (de) * 1985-12-17 1989-09-15 Hamilton Bonaduz Ag
CA1286389C (en) * 1986-04-17 1991-07-16 Robert J. Sarrine Automatic pipetting apparatus
JPH0623771B2 (ja) * 1986-05-22 1994-03-30 富士写真フイルム株式会社 自動点着装置
US5957167A (en) * 1997-12-18 1999-09-28 Pharmacopeia, Inc. Article for dispensing small volumes of liquid
US6143252A (en) * 1999-04-12 2000-11-07 The Perkin-Elmer Corporation Pipetting device with pipette tip for solid phase reactions
DE19962689C2 (de) * 1999-12-23 2002-02-07 Tecconsult & Trading Ohg Vorrichtung zum Auftragen von flüssigen Proben mittels Pipetten auf Platten, Folie o. dgl.

Also Published As

Publication number Publication date
US6672344B1 (en) 2004-01-06
DE60208231T2 (de) 2006-08-10
WO2003037515A1 (en) 2003-05-08
JP4223401B2 (ja) 2009-02-12
ATE313380T1 (de) 2006-01-15
EP1444043A1 (de) 2004-08-11
JP2005507998A (ja) 2005-03-24
EP1444043B1 (de) 2005-12-21

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: APPLIED BIOSYSTEMS, LLC (N. D. GES. D. STAATES, US