DE60126130D1 - In-vitro verfahren zur herstellung und identifizierung von immunglobulin moleküle in eukaryotischen zellen - Google Patents

In-vitro verfahren zur herstellung und identifizierung von immunglobulin moleküle in eukaryotischen zellen

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Publication number
DE60126130D1
DE60126130D1 DE60126130T DE60126130T DE60126130D1 DE 60126130 D1 DE60126130 D1 DE 60126130D1 DE 60126130 T DE60126130 T DE 60126130T DE 60126130 T DE60126130 T DE 60126130T DE 60126130 D1 DE60126130 D1 DE 60126130D1
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DE
Germany
Prior art keywords
immunoglobulin molecules
eukaryotic cells
antigen
identification
manufacture
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
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DE60126130T
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English (en)
Other versions
DE60126130T2 (de
Inventor
Maurice Zauderer
S Smith
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Rochester
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University of Rochester
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Publication date
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Publication of DE60126130D1 publication Critical patent/DE60126130D1/de
Publication of DE60126130T2 publication Critical patent/DE60126130T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/22—Immunoglobulins specific features characterized by taxonomic origin from camelids, e.g. camel, llama or dromedary
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/55—Fab or Fab'
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
    • C07K2317/622—Single chain antibody (scFv)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00—Uses of viruses
    • C12N2799/02—Uses of viruses as vector
    • C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
    • C12N2799/023—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a poxvirus
DE60126130T 2000-11-17 2001-11-14 In-vitro verfahren zur herstellung und identifizierung von immunglobulin moleküle in eukaryotischen zellen Expired - Lifetime DE60126130T2 (de)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US24926800P 2000-11-17 2000-11-17
US249268P 2000-11-17
US26206701P 2001-01-18 2001-01-18
US262067P 2001-01-18
US27142401P 2001-02-27 2001-02-27
US271424P 2001-02-27
US29808701P 2001-06-15 2001-06-15
US298087P 2001-06-15
PCT/US2001/043076 WO2002102855A2 (en) 2000-11-17 2001-11-14 In vitro methods of producing and identifying immunoglobulin molecules in eukaryotic cells

Publications (2)

Publication Number Publication Date
DE60126130D1 true DE60126130D1 (de) 2007-03-08
DE60126130T2 DE60126130T2 (de) 2007-10-18

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
DE60126130T Expired - Lifetime DE60126130T2 (de) 2000-11-17 2001-11-14 In-vitro verfahren zur herstellung und identifizierung von immunglobulin moleküle in eukaryotischen zellen

Country Status (9)

Country Link
US (2) US7858559B2 (de)
EP (1) EP1340088B1 (de)
JP (1) JP4368196B2 (de)
CN (1) CN1306272C (de)
AT (1) ATE352040T1 (de)
AU (1) AU2001297872B2 (de)
CA (1) CA2429544C (de)
DE (1) DE60126130T2 (de)
WO (1) WO2002102855A2 (de)

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US20080167193A1 (en) 2008-07-10
JP4368196B2 (ja) 2009-11-18
US7858559B2 (en) 2010-12-28
CA2429544A1 (en) 2002-12-27
US8741810B2 (en) 2014-06-03
DE60126130T2 (de) 2007-10-18
EP1340088A2 (de) 2003-09-03
CN1527944A (zh) 2004-09-08
JP2004532645A (ja) 2004-10-28
CA2429544C (en) 2010-10-19
AU2001297872B2 (en) 2006-11-09
CN1306272C (zh) 2007-03-21
US20020123057A1 (en) 2002-09-05
EP1340088B1 (de) 2007-01-17
WO2002102855A3 (en) 2003-06-26
WO2002102855A2 (en) 2002-12-27
ATE352040T1 (de) 2007-02-15

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