DE3853566T2 - Formulierungen von Tetrazyklinverbindungen mit kontrollierter Freisetzung. - Google Patents

Formulierungen von Tetrazyklinverbindungen mit kontrollierter Freisetzung.

Info

Publication number
DE3853566T2
DE3853566T2 DE3853566T DE3853566T DE3853566T2 DE 3853566 T2 DE3853566 T2 DE 3853566T2 DE 3853566 T DE3853566 T DE 3853566T DE 3853566 T DE3853566 T DE 3853566T DE 3853566 T2 DE3853566 T2 DE 3853566T2
Authority
DE
Germany
Prior art keywords
controlled release
release formulations
tetracycline compounds
tetracycline
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE3853566T
Other languages
English (en)
Other versions
DE3853566D1 (de
Inventor
Joseph J Valerose Jr
Raymond J Biehl
Nitin V Sheth
Walter A Strathy
Michael Kay Doelling
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth Holdings LLC
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22303124&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE3853566(T2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Application granted granted Critical
Publication of DE3853566D1 publication Critical patent/DE3853566D1/de
Publication of DE3853566T2 publication Critical patent/DE3853566T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/65—Tetracyclines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
DE3853566T 1987-10-06 1988-09-01 Formulierungen von Tetrazyklinverbindungen mit kontrollierter Freisetzung. Expired - Lifetime DE3853566T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/104,917 US4837030A (en) 1987-10-06 1987-10-06 Novel controlled release formulations of tetracycline compounds

Publications (2)

Publication Number Publication Date
DE3853566D1 DE3853566D1 (de) 1995-05-18
DE3853566T2 true DE3853566T2 (de) 1996-01-11

Family

ID=22303124

Family Applications (1)

Application Number Title Priority Date Filing Date
DE3853566T Expired - Lifetime DE3853566T2 (de) 1987-10-06 1988-09-01 Formulierungen von Tetrazyklinverbindungen mit kontrollierter Freisetzung.

Country Status (24)

Country Link
US (1) US4837030A (de)
EP (1) EP0310814B1 (de)
JP (1) JP2771189B2 (de)
KR (1) KR970007902B1 (de)
AR (1) AR243077A1 (de)
AT (1) ATE120957T1 (de)
AU (1) AU609525B2 (de)
CA (1) CA1338439C (de)
CZ (1) CZ279809B6 (de)
DE (1) DE3853566T2 (de)
DK (1) DK175578B1 (de)
ES (1) ES2070837T3 (de)
FI (1) FI97862C (de)
GR (1) GR3015767T3 (de)
HK (1) HK1000313A1 (de)
HU (1) HU202110B (de)
IL (1) IL87699A (de)
NO (1) NO175619C (de)
NZ (1) NZ226396A (de)
PH (1) PH27236A (de)
PL (1) PL275089A1 (de)
PT (1) PT88664B (de)
SK (1) SK278567B6 (de)
ZA (1) ZA887478B (de)

Families Citing this family (54)

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DE3887179T2 (de) * 1987-03-02 1994-06-16 Brocades Pharma Bv Pharmazeutische Zusammensetzung, pharmazeutisches Granulat und Verfahren zu ihrer Herstellung.
US5211958A (en) * 1987-11-30 1993-05-18 Gist-Brocades, N.V. Pharmaceutical composition and process for its preparation
US5277916A (en) * 1988-02-01 1994-01-11 F. H. Faulding & Co., Ltd. Tetracycline dosage form
ES2060737T3 (es) * 1988-02-25 1994-12-01 Yamanouchi Europ Bv Procedimiento de preparacion de un granulado farmaceutico.
EP0418596A3 (en) * 1989-09-21 1991-10-23 American Cyanamid Company Controlled release pharmaceutical compositions from spherical granules in tabletted oral dosage unit form
ATE114472T1 (de) * 1989-09-21 1994-12-15 American Cyanamid Co System des typs ''einmal täglich'' zur gepulsten minocyclinabgabe.
EP0418597A3 (en) * 1989-09-21 1991-11-27 American Cyanamid Company Controlled release carbonic anhydrase inhibitor containing pharmaceutical compositions from spherical granules in capsule oral dosage unit form
US5460825A (en) * 1990-05-23 1995-10-24 Mcneil-Ppc, Inc. Taste mask coatings for preparing chewable pharmaceutical tablets
US5260072A (en) * 1990-08-30 1993-11-09 Mcneil-Ppc, Inc. Rotogranulations and taste masking coatings for preparation of chewable pharmaceutical tablets
US5494903A (en) 1991-10-04 1996-02-27 American Cyanamid Company 7-substituted-9-substituted amino-6-demethyl-6-deoxytetracyclines
USRE40183E1 (en) 1991-10-04 2008-03-25 Wyeth Holdings Corporation 7-Substituted-9-substituted amino-6-demethyl-6-deoxytetracyclines
DE69231499T2 (de) * 1991-12-30 2001-05-03 Fmc Corp Zusammensetzung auf der basis von mikrokristalliner zellulose für die herstellung von kugelförmigen teilchen
US5262173A (en) * 1992-03-02 1993-11-16 American Cyanamid Company Pulsatile once-a-day delivery systems for minocycline
US5614223A (en) * 1992-05-04 1997-03-25 Digestive Care Inc. Intraoral medicament-releasing device
CA2093282C (en) * 1992-05-04 1999-01-12 Tibor Sipos Intraoral medicament-releasing device
US6224911B1 (en) * 1993-03-16 2001-05-01 Syntex (U.S.A.) Llc Process for the preparation of enteric coated pharmaceutical dosage forms
US5536507A (en) * 1994-06-24 1996-07-16 Bristol-Myers Squibb Company Colonic drug delivery system
US20030215507A1 (en) * 1996-03-25 2003-11-20 Wyeth Extended release formulation
US20060068001A1 (en) * 1996-03-25 2006-03-30 Wyeth Extended release formulation
US6230052B1 (en) 1999-01-29 2001-05-08 Andy Wolff Device and method for stimulating salivation
US20050037065A1 (en) * 1999-05-27 2005-02-17 Drugtech Corporation Nutritional formulations
WO2000072831A1 (en) * 1999-05-27 2000-12-07 Drugtech Corporation Nutritional formulations
AU2002256092C1 (en) * 2001-04-05 2009-10-15 Collagenex Pharmaceuticals, Inc. Controlled delivery of tetracycline compounds and tetracycline derivatives
WO2003053402A1 (en) * 2001-12-20 2003-07-03 Pharmacia Corporation Zero-order sustained released dosage forms and method of making the same
AU2003213876B2 (en) * 2002-04-12 2006-10-12 Mayne Pharma International Pty Ltd An improved modified release preparation
US6958161B2 (en) * 2002-04-12 2005-10-25 F H Faulding & Co Limited Modified release coated drug preparation
AUPS167602A0 (en) * 2002-04-12 2002-05-16 F.H. Faulding & Co. Limited An improved modified release preparation
AU2003284942A1 (en) * 2002-10-30 2004-06-07 Pharmacia Corporation Oral extended release tablets and methods of making and using the same
US20040158194A1 (en) * 2003-02-06 2004-08-12 Wolff Andy And Beiski Ben Z. Oral devices and methods for controlled drug release
PL1615622T3 (pl) 2003-04-07 2012-12-31 Supernus Pharmaceuticals Inc Preparaty doksycyklin do jednorazowego dziennego podawania
GB2414668B (en) * 2004-06-03 2009-07-29 Dexcel Ltd Tetracycline modified release delivery system
CN101128206A (zh) * 2005-01-21 2008-02-20 沃纳奇尔科特公司 固体剂型形式的四环素类金属络合物
WO2006082525A1 (en) * 2005-02-04 2006-08-10 Philip Morris Products S.A. Cigarette and filter with cellulosic flavor addition
US20070106138A1 (en) * 2005-05-26 2007-05-10 Beiski Ben Z Intraoral apparatus for non-invasive blood and saliva monitoring & sensing
US20080241235A1 (en) * 2007-04-02 2008-10-02 Medicis Pharmaceutical Corporation Minocycline oral dosage forms for the treatment of acne
US8252776B2 (en) 2007-04-02 2012-08-28 Medicis Pharmaceutical Corporation Minocycline oral dosage forms for the treatment of acne
US8722650B1 (en) 2005-06-24 2014-05-13 Medicis Pharmaceutical Corporation Extended-release minocycline dosage forms
US20080242642A1 (en) 2007-04-02 2008-10-02 Medicis Pharmaceutical Corporation Minocycline oral dosage forms for the treatment of acne
US7541347B2 (en) * 2007-04-02 2009-06-02 Medicis Pharmaceutical Coropration Minocycline oral dosage forms for the treatment of acne
US7544373B2 (en) * 2007-04-02 2009-06-09 Medicis Pharmaceutical Corporation Minocycline oral dosage forms for the treatment of acne
US7919483B2 (en) * 2005-06-24 2011-04-05 Medicis Pharmaceutical Corporation Method for the treatment of acne
EP1965770A2 (de) * 2005-12-22 2008-09-10 Wyeth a Corporation of the State of Delaware Orale formulierungen mit tigecyclin
US20070166273A1 (en) * 2006-01-19 2007-07-19 Krivulka Joseph J Skin treatment educational kit
JP5527921B2 (ja) * 2006-12-22 2014-06-25 エスエス製薬株式会社 苦味を隠蔽した経口固形組成物
ITMI20070022A1 (it) 2007-01-09 2008-07-10 I P S Internat Products & Services Srl Formulazione di prodotti solidi a rilascio controllato per uso orale in bustine monodose e relativo procedimento di preparazione
AP2657A (en) * 2007-03-23 2013-05-07 Molecular Res Ct Inc Anti-inflammatory compositions comprising tetracyclines and use thereof in therapy
US20080241197A1 (en) * 2007-04-02 2008-10-02 Medicis Pharmaceutical Corporation Minocycline dosage forms for the treatment of acne
PT2271348T (pt) 2008-03-28 2018-04-16 Paratek Pharm Innc Formulação de comprimido oral de composto de tetraciclina
WO2010017310A1 (en) * 2008-08-06 2010-02-11 Medicis Pharmaceutical Corporation Method for the treatment of acne and certain dosage forms thereof
US9561241B1 (en) 2011-06-28 2017-02-07 Medicis Pharmaceutical Corporation Gastroretentive dosage forms for minocycline
WO2013122260A1 (en) * 2012-02-15 2013-08-22 Takeda Pharmaceutical Company Limited Tablet
ME03656B (de) 2013-03-15 2020-07-20 Braintree Laboratories Inc Doppelt verwendbare orale tabletten einer pharmazeutischen zusammensetzung aus sulfatsalzen und verfahren zur verwendung davon
US20170182070A1 (en) 2014-10-08 2017-06-29 Mayne Pharma International Pty Ltd. Controlled Release Doxycycline
WO2016162754A1 (en) 2015-04-07 2016-10-13 Dr. Reddy's Laboratories Ltd. Pharmaceutical compositions for minocycline

Family Cites Families (21)

* Cited by examiner, † Cited by third party
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US3148212A (en) * 1961-12-22 1964-09-08 American Cyanamid Co Reductive alkylation process
USRE26253E (en) * 1963-05-17 1967-08-15 And z-alkylamino-g-deoxytetracycline
US3356571A (en) * 1964-11-25 1967-12-05 American Cyanamid Co Potentiation of tetracycline by polyacrylic acid or hydrolyzed polyacrylonitrile
CH434240A (de) * 1965-12-30 1967-04-30 Chemical And Pharmaceutical Pa Verfahren zur Herstellung einer therapeutischen Tetracyclinzubereitung mit verlängerter therapeutischer Wirkung
CH434571A (de) * 1966-07-05 1967-04-30 Chemical And Pharmaceutical Pa Verfahren zur Herstellung von Antibiotika mit verlängerter therapeutischer Wirkung
DE1617393C2 (de) * 1966-01-06 1982-11-11 Československá akademie věd, Praha Verfahren zur Herstellung von biologisch aktive Stoffe enthaltenden hydrophilen vernetzten Copolymeren
US4207258A (en) * 1972-02-24 1980-06-10 Ankerfarm S.P.A. Process for the preparatin of α-6-deoxytetracyclines
FR2183546B1 (de) * 1972-05-10 1975-06-20 Servier Lab
US4038315A (en) * 1972-05-11 1977-07-26 American Cyanamid Company Isolation and recovery of calcium chloride complex of 7-dimethylamino-6-dimethyl l-6-deoxytetracycline hydrochloride
CH582002A5 (de) * 1972-06-09 1976-11-30 Purdue Research Foundation
NL158172B (nl) * 1972-09-18 1978-10-16 Farmaceutici Italia Werkwijze voor het bereiden van tetracyclinederivaten met een substituent op de 7-plaats.
JPS4941522A (de) * 1973-05-17 1974-04-18
GB1413186A (en) * 1973-06-27 1975-11-12 Toyo Jozo Kk Process for encapsulation of medicaments
US4088798A (en) * 1975-11-11 1978-05-09 Sandoz, Inc. Methods for the preparation of controlled gastric residence time medicament formulations
US4154827A (en) * 1977-12-15 1979-05-15 University Of Pennsylvania Inhibition of ADH-stimulated osmotic water flow and aldosterone-stimulated sodium transport
GB2042888B (en) * 1979-03-05 1983-09-28 Teijin Ltd Preparation for administration to the mucosa of the oral or nasal cavity
US4622244A (en) * 1979-09-04 1986-11-11 The Washington University Process for preparation of microcapsules
ES8307096A1 (es) * 1981-06-01 1983-07-01 Orion Yhtymae Oy "un metodo para preparar tabletas a base de polvos de medicamento acidicos, inocuas para el esofago".
US4369172A (en) * 1981-12-18 1983-01-18 Forest Laboratories Inc. Prolonged release therapeutic compositions based on hydroxypropylmethylcellulose
US4550096A (en) * 1982-01-19 1985-10-29 Plurichemie Anstalt Homogeneous catalytic system comprising rhodium, hydrazine and phosphine and a process for the preparation of same
US4701320A (en) * 1984-11-29 1987-10-20 Lederle (Japan), Ltd. Composition stably containing minocycline for treating periodontal diseases

Also Published As

Publication number Publication date
AU2344488A (en) 1989-04-06
NO175619B (de) 1994-08-01
HK1000313A1 (en) 1998-02-27
IL87699A0 (en) 1989-02-28
FI97862C (fi) 1997-03-10
EP0310814A3 (en) 1989-05-03
ZA887478B (en) 1989-06-28
JPH01128929A (ja) 1989-05-22
CZ656388A3 (en) 1995-02-15
IL87699A (en) 1994-06-24
AU609525B2 (en) 1991-05-02
PL275089A1 (en) 1989-07-10
PH27236A (en) 1993-05-04
DK556788D0 (da) 1988-10-05
DK556788A (da) 1989-04-07
JP2771189B2 (ja) 1998-07-02
PT88664B (pt) 2003-06-30
NO884408L (no) 1989-04-07
AR243077A1 (es) 1993-07-30
ATE120957T1 (de) 1995-04-15
SK656388A3 (en) 1997-10-08
FI97862B (fi) 1996-11-29
EP0310814A2 (de) 1989-04-12
GR3015767T3 (en) 1995-07-31
EP0310814B1 (de) 1995-04-12
SK278567B6 (en) 1997-10-08
DE3853566D1 (de) 1995-05-18
US4837030A (en) 1989-06-06
NO175619C (no) 1994-11-09
FI884575A (fi) 1989-04-07
FI884575A0 (fi) 1988-10-05
CA1338439C (en) 1996-07-09
CZ279809B6 (cs) 1995-07-12
NZ226396A (en) 1991-08-27
DK175578B1 (da) 2004-12-13
HUT50046A (en) 1989-12-28
NO884408D0 (no) 1988-10-05
KR970007902B1 (ko) 1997-05-17
PT88664A (pt) 1989-07-31
KR890006242A (ko) 1989-06-12
HU202110B (en) 1991-02-28
ES2070837T3 (es) 1995-06-16

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: WYETH HOLDINGS CORP., MADISON, N.J., US