DE3689391D1 - Rekombinanter koloniestimulierender faktor-1. - Google Patents

Rekombinanter koloniestimulierender faktor-1.

Info

Publication number
DE3689391D1
DE3689391D1 DE86901580T DE3689391T DE3689391D1 DE 3689391 D1 DE3689391 D1 DE 3689391D1 DE 86901580 T DE86901580 T DE 86901580T DE 3689391 T DE3689391 T DE 3689391T DE 3689391 D1 DE3689391 D1 DE 3689391D1
Authority
DE
Germany
Prior art keywords
stimulating factor
recombinant colony
colony
recombinant
stimulating
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE86901580T
Other languages
English (en)
Other versions
DE3689391T2 (de
Inventor
Ernest Kawasaki
Martha Ladner
Arsdell Janelle Van
Alice Wang
Peter Ralph
Mazie Coyne
Mary Warren
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis Vaccines and Diagnostics Inc
Original Assignee
Cetus Oncology Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cetus Oncology Corp filed Critical Cetus Oncology Corp
Publication of DE3689391D1 publication Critical patent/DE3689391D1/de
Application granted granted Critical
Publication of DE3689391T2 publication Critical patent/DE3689391T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
    • C12N15/73—Expression systems using phage (lambda) regulatory sequences
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/53—Colony-stimulating factor [CSF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Toxicology (AREA)
  • Microbiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Plant Pathology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DE3689391T 1985-02-05 1986-02-03 Rekombinanter koloniestimulierender faktor-1. Expired - Lifetime DE3689391T2 (de)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US69835985A 1985-02-05 1985-02-05
US72883485A 1985-04-30 1985-04-30
US74492485A 1985-06-14 1985-06-14
US75681485A 1985-07-18 1985-07-18
US82106886A 1986-01-29 1986-01-29
PCT/US1986/000238 WO1986004607A1 (en) 1985-02-05 1986-02-03 Recombinant colony stimulating factor-1

Publications (2)

Publication Number Publication Date
DE3689391D1 true DE3689391D1 (de) 1994-01-27
DE3689391T2 DE3689391T2 (de) 1994-06-30

Family

ID=27542097

Family Applications (1)

Application Number Title Priority Date Filing Date
DE3689391T Expired - Lifetime DE3689391T2 (de) 1985-02-05 1986-02-03 Rekombinanter koloniestimulierender faktor-1.

Country Status (11)

Country Link
US (1) US5470569A (de)
EP (1) EP0209601B1 (de)
JP (2) JP2561255B2 (de)
AU (2) AU594045B2 (de)
BG (1) BG49941A3 (de)
DE (1) DE3689391T2 (de)
DK (1) DK172843B1 (de)
FI (1) FI100972B (de)
IL (1) IL77789A (de)
NO (1) NO179109C (de)
WO (1) WO1986004607A1 (de)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5422105A (en) * 1985-02-05 1995-06-06 Cetus Oncology Corporation Use of recombinant colony stimulating factor 1
US6156300A (en) * 1985-02-05 2000-12-05 Chiron Corporation Point mutants of N∇2 CSF-1 and carboxy truncated fragments thereof
US5792450A (en) * 1985-02-05 1998-08-11 Chiron Corporation Purified human CSF-1
US6103224A (en) * 1985-02-05 2000-08-15 Chiron Corporation N∇2 CSF-1 (short form) and carboxy truncated fragments thereof
US5573930A (en) 1985-02-05 1996-11-12 Cetus Oncology Corporation DNA encoding various forms of colony stimulating factor-1
US5837229A (en) * 1985-02-05 1998-11-17 Chiron Corporation Uses of recombinant colony stimulating factor-1
JP2561255B2 (ja) * 1985-02-05 1996-12-04 シタス コ−ポレイシヨン 組換コロニ−刺激因子▲下−▼１
US5104650A (en) * 1985-02-05 1992-04-14 Cetus Corporation Uses of recombinant colony stimulating factor-1
US5556620A (en) * 1985-02-05 1996-09-17 Cetus Oncology Corporation Use of recombinant colony stimulating factor-1 to enhance wound healing
EP0307402B1 (de) * 1986-05-06 1993-08-11 Genetics Institute, Inc. Herstellung von m-csf
DK298687A (da) * 1986-06-12 1987-12-13 Immunex Corp Funktionelle, rekombinerede analoge polypeptider, som er fri for hydrofobe aminosyrer
US5650297A (en) * 1986-09-17 1997-07-22 Otsuka Pharmaceutical Co., Ltd. DNA encoding human colony-stimulating factors
JP2583770B2 (ja) * 1986-09-17 1997-02-19 大塚製薬株式会社 遺伝子
HU215241B (hu) * 1986-10-24 1998-11-30 Cetus Corp. Eljárás telepstimuláló faktor-1 új formáinak előállítására, valamint az eljárásban alkalmazható expressziós kazetta, vektor és rekombináns gazdasejtek előállítására
AU8313187A (en) * 1986-12-31 1988-07-07 Cetus Corporation Pharmaceutical composition of colony stimulating factor-i and granulocyte colony stimulating factor
IL86090A (en) * 1987-04-16 1993-03-15 Cetus Oncology Corp Production of purified, biologically active, bacterially produced recombinant human csf-1
CA1339757C (en) * 1987-04-16 1998-03-17 Robert F. Halenbeck Production of purified biologically active, bacterially produced recombinant human csf-1
US4929700A (en) * 1987-04-16 1990-05-29 Cetus Corporation Production of purified, biologically active, bacterially produced recombinant human CSF-1
JP2831012B2 (ja) * 1987-09-22 1998-12-02 カイロン コーポレイション 組換えコロニー刺激因子‐１の使用
JP2791418B2 (ja) 1987-12-02 1998-08-27 株式会社ミドリ十字 異種蛋白質の製造方法、組換えｄｎａ、形質転換体
US4847325A (en) * 1988-01-20 1989-07-11 Cetus Corporation Conjugation of polymer to colony stimulating factor-1
DK54589A (da) * 1988-02-08 1989-08-09 Otsuka Pharma Co Ltd Humane kolonistmulerende faktorer
EP0411033B1 (de) * 1988-04-29 1994-09-07 Genetics Institute, Inc. Lagerungsstabile zusammensetzungen von homogenem dimerem m-csf
US5888495A (en) * 1988-05-23 1999-03-30 Genetics Institute, Inc. Method of producing storage stable M-CSF lyophilizates
US5171675A (en) * 1988-07-28 1992-12-15 Cerretti Douglas P Macrophage colony stimulating factor-γ
US5288487A (en) * 1989-02-28 1994-02-22 Morinaga Milk Industry Co., Ltd. Human monocyte-macrophage-CSF preparations
EP0385385B1 (de) * 1989-02-28 1995-09-27 Morinaga Milk Industry Co., Ltd. Menschlichen Monozyt-Makrophagen-Koloniestimulierungsfaktor enthaltende Zusammensetzung
JPH02225418A (ja) * 1989-02-28 1990-09-07 Morinaga Milk Ind Co Ltd 抗悪性腫瘍剤
WO1990012877A1 (en) * 1989-04-19 1990-11-01 Cetus Corporation Multifunctional m-csf proteins and genes encoding therefor
AU1137699A (en) * 1997-11-07 1999-05-31 Dalhousie University Novel reovirus-derived proteins, nucleic acids encoding same, and uses therefor
US7108852B2 (en) 2000-03-20 2006-09-19 Warner-Lambert Company Llc Methods of treating inflammation using antibodies to M-CSF
AR045563A1 (es) * 2003-09-10 2005-11-02 Warner Lambert Co Anticuerpos dirigidos a m-csf
US20070099239A1 (en) * 2005-06-24 2007-05-03 Raymond Tabibiazar Methods and compositions for diagnosis and monitoring of atherosclerotic cardiovascular disease

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6030291B2 (ja) * 1978-03-20 1985-07-16 森永乳業株式会社 人顆粒球の分化増殖を促進するｈｇｉ糖蛋白質、ｈｇｉ糖蛋白質の製造法及びｈｇｉ糖蛋白質を含有する白血球減少症治療剤
US4230697A (en) * 1978-07-03 1980-10-28 Morinaga Milk Industry Co. Ltd. Virus-inactivated HGI-glycoprotein capable of stimulating proliferation and differentiation of human granulocyte, process for preparing same and leukopenia curative containing same
US4342828A (en) * 1979-07-20 1982-08-03 Morinaga Milk Industry Co., Ltd. Method for producing substance capable of stimulating differentiation and proliferation of human granulopoietic stem cells
JPS5758629A (en) * 1980-09-25 1982-04-08 Morinaga Milk Ind Co Ltd Separating and purifying method of colonization stimulating factor and callicrein in human urine
JPS6030654B2 (ja) * 1980-12-31 1985-07-17 株式会社林原生物化学研究所 ヒトコロニ−刺激因子の製造方法
US4438032A (en) 1981-01-30 1984-03-20 The Regents Of The University Of California Unique T-lymphocyte line and products derived therefrom
US4432895A (en) * 1982-11-24 1984-02-21 Hoffmann-La Roche Inc. Monomeric interferons
US4485017A (en) * 1982-12-22 1984-11-27 Cetus Corporation Isolation of human interferon by immunosorbent and high performance liquid chromatography
JPS59137417A (ja) * 1983-01-28 1984-08-07 Morinaga Milk Ind Co Ltd 人尿由来コロニ−形成刺激因子及びカリクレインの製造法
US4504586A (en) * 1983-02-03 1985-03-12 Amgen Hybridoma tumor cell lines and their monoclonal antibodies to human colony stimulating factor subclass number 1
JPS6041615A (ja) * 1983-08-12 1985-03-05 Green Cross Corp:The コロニ−形成刺激因子の製造方法
US4658018A (en) * 1984-03-13 1987-04-14 Immunex Corporation Process for producing homogeneous colony stimulating factor
JPS61227526A (ja) * 1984-07-25 1986-10-09 Chugai Pharmaceut Co Ltd 新規なコロニー刺激因子
JP2561255B2 (ja) * 1985-02-05 1996-12-04 シタス コ−ポレイシヨン 組換コロニ−刺激因子▲下−▼１
DE3686794T2 (de) * 1985-02-05 1993-03-04 Cetus Oncology Corp Reinigung des natuerlichen kolonie-stimulierenden faktors-1.
JPS629323A (ja) * 1985-07-08 1987-01-17 Seiko Epson Corp 液晶素子の駆動方法
AU589731B2 (en) * 1985-11-27 1989-10-19 Genetics Institute, Llc Colony stimulating factor for the treatment of aids-type diseases
EP0307402B1 (de) * 1986-05-06 1993-08-11 Genetics Institute, Inc. Herstellung von m-csf
US4879227A (en) * 1986-05-06 1989-11-07 Genetics Institute, Inc. Production of a recombinant human colony stimulating factor
US4868119A (en) * 1986-12-11 1989-09-19 Genetics Institute, Inc. Hematopoietic growth factors
DK298687A (da) * 1986-06-12 1987-12-13 Immunex Corp Funktionelle, rekombinerede analoge polypeptider, som er fri for hydrofobe aminosyrer
JP2583770B2 (ja) * 1986-09-17 1997-02-19 大塚製薬株式会社 遺伝子
US5171675A (en) * 1988-07-28 1992-12-15 Cerretti Douglas P Macrophage colony stimulating factor-γ

Also Published As

Publication number Publication date
AU5013090A (en) 1990-11-01
EP0209601B1 (de) 1993-12-15
AU626639B2 (en) 1992-08-06
AU5517386A (en) 1986-08-26
BG49941A3 (en) 1992-03-16
FI864016A (fi) 1986-10-03
JPS62501607A (ja) 1987-07-02
FI864016A0 (fi) 1986-10-03
NO863952D0 (no) 1986-10-03
DK474686A (da) 1986-12-05
DE3689391T2 (de) 1994-06-30
FI100972B (fi) 1998-03-31
NO179109B (no) 1996-04-29
AU594045B2 (en) 1990-03-01
WO1986004607A1 (en) 1986-08-14
DK172843B1 (da) 1999-08-09
JP2561255B2 (ja) 1996-12-04
EP0209601A1 (de) 1987-01-28
US5470569A (en) 1995-11-28
IL77789A (en) 1992-03-29
DK474686D0 (da) 1986-10-03
NO863952L (no) 1986-10-03
NO179109C (no) 1996-08-07
JPH07163391A (ja) 1995-06-27
JP2553829B2 (ja) 1996-11-13

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: CHIRON CORP. (N.D.GES.D. STAATES DELAWARE), EMERYV

8327 Change in the person/name/address of the patent owner

Owner name: NOVARTIS VACCINES AND DIAGNOSTICS,INC.(N.D.GES, US