DE3265736D1 - A method for carrying out non-isotopic immunoassays, labeled analytes and kits for use in such assays - Google Patents

A method for carrying out non-isotopic immunoassays, labeled analytes and kits for use in such assays

Info

Publication number
DE3265736D1
DE3265736D1 DE8282102640T DE3265736T DE3265736D1 DE 3265736 D1 DE3265736 D1 DE 3265736D1 DE 8282102640 T DE8282102640 T DE 8282102640T DE 3265736 T DE3265736 T DE 3265736T DE 3265736 D1 DE3265736 D1 DE 3265736D1
Authority
DE
Germany
Prior art keywords
analyte
polypeptide
substrate
labeled
reporter molecule
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8282102640T
Other languages
English (en)
Inventor
Peter R Farina
James R Gohlke
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Diagnostics Corp
Original Assignee
Biochem Immunosystems US Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biochem Immunosystems US Inc filed Critical Biochem Immunosystems US Inc
Application granted granted Critical
Publication of DE3265736D1 publication Critical patent/DE3265736D1/de
Expired legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/542—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals
    • G01N33/535—Production of labelled immunochemicals with enzyme label or co-enzymes, co-factors, enzyme inhibitors or enzyme substrates
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/81—Packaged device or kit
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/967—Standards, controls, materials, e.g. validation studies, buffer systems
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/968—High energy substrates, e.g. fluorescent, chemiluminescent, radioactive
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/971—Capture of complex after antigen-antibody reaction
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/975—Kit
DE8282102640T 1981-03-30 1982-03-29 A method for carrying out non-isotopic immunoassays, labeled analytes and kits for use in such assays Expired DE3265736D1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/248,689 US4378428A (en) 1981-03-30 1981-03-30 Method for carrying out non-isotopic immunoassays, labeled analytes and kits for use in such assays

Publications (1)

Publication Number Publication Date
DE3265736D1 true DE3265736D1 (en) 1985-10-03

Family

ID=22940245

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8282102640T Expired DE3265736D1 (en) 1981-03-30 1982-03-29 A method for carrying out non-isotopic immunoassays, labeled analytes and kits for use in such assays

Country Status (7)

Country Link
US (1) US4378428A (de)
EP (1) EP0062277B1 (de)
JP (1) JPS58757A (de)
AT (1) ATE15275T1 (de)
CA (1) CA1199868A (de)
DE (1) DE3265736D1 (de)
IE (1) IE52423B1 (de)

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US5382582A (en) * 1993-03-26 1995-01-17 Chan; Carcy L. Methotrexate analogs and methods of using same
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US6365334B1 (en) 1993-10-22 2002-04-02 Eastman Kodak Company Photographic elements containing aryloxypyrazolone couplers and sulfur containing stabilizers
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US8148110B2 (en) * 1999-03-15 2012-04-03 The Board Of Trustees Of The Leland Stanford Junior University Detection of molecular interactions by β-lactamase reporter fragment complementation
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JP4796059B2 (ja) * 2004-06-30 2011-10-19 ディスカヴァーエックス コーポレイション 細胞内修飾の分析
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US8101373B2 (en) * 2007-10-12 2012-01-24 Discoverx Corporation β-galactosidase donor fragments
JP5628498B2 (ja) * 2009-08-26 2014-11-19 株式会社ブリヂストン 有機ケイ素化合物、それを含む有機ケイ素化合物組成物、ゴム組成物、プライマー組成物、塗料組成物、接着剤、及びタイヤ
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Also Published As

Publication number Publication date
CA1199868A (en) 1986-01-28
IE820574L (en) 1982-09-30
EP0062277A1 (de) 1982-10-13
US4378428A (en) 1983-03-29
IE52423B1 (en) 1987-10-28
JPH0220066B2 (de) 1990-05-08
JPS58757A (ja) 1983-01-05
EP0062277B1 (de) 1985-08-28
ATE15275T1 (de) 1985-09-15

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Owner name: GALENO B.V., AMSTERDAM, NL

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Owner name: PHARMINVEST S.A., LUXEMBOURG, LU

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Owner name: BOEHRINGER MANNHEIM CORP., INDIANAPOLIS, IND., US

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Owner name: ROCHE DIAGNOSTICS CORP., INDIANAPOLIS, IND., US