CN1244376A - 可由导管输送的螺旋线血栓形成装置和血栓形成方法 - Google Patents

可由导管输送的螺旋线血栓形成装置和血栓形成方法 Download PDF

Info

Publication number
CN1244376A
CN1244376A CN98105499A CN98105499A CN1244376A CN 1244376 A CN1244376 A CN 1244376A CN 98105499 A CN98105499 A CN 98105499A CN 98105499 A CN98105499 A CN 98105499A CN 1244376 A CN1244376 A CN 1244376A
Authority
CN
China
Prior art keywords
helix
conduit
tinsel
far
elasticity
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN98105499A
Other languages
English (en)
Inventor
斯迪芬·C·贾考波森
克拉克·C·戴维斯
约翰·A·里泊特
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sarcos LC
Original Assignee
Sarcos LC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sarcos LC filed Critical Sarcos LC
Publication of CN1244376A publication Critical patent/CN1244376A/zh
Pending legal-status Critical Current

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
    • A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
    • A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
    • A61B17/12099—Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder
    • A61B17/12109—Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder in a blood vessel
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
    • A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
    • A61B17/12131—Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device
    • A61B17/1214—Coils or wires
    • A61B17/12145—Coils or wires having a pre-set deployed three-dimensional shape
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
    • A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
    • A61B17/12131—Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device
    • A61B17/12168—Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device having a mesh structure
    • A61B17/12172—Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device having a mesh structure having a pre-set deployed three-dimensional shape
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/01—Filters implantable into blood vessels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/01—Filters implantable into blood vessels
    • A61F2002/016—Filters implantable into blood vessels made from wire-like elements
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2230/00—Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2230/0002—Two-dimensional shapes, e.g. cross-sections
    • A61F2230/0004—Rounded shapes, e.g. with rounded corners
    • A61F2230/0006—Rounded shapes, e.g. with rounded corners circular
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2230/00—Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2230/0063—Three-dimensional shapes
    • A61F2230/0091—Three-dimensional shapes helically-coiled or spirally-coiled, i.e. having a 2-D spiral cross-section

Abstract

一种可由导管输送的血栓形成装置,包括一个穿入体内脉管系统通道到达目标位置的导管,和一个弹性金属丝元件,该元件螺旋缠绕并具一定形状,以便在未受约束时占据一定空间,而当沿导管长度方向插入并受导管约束时变平直,从而最终从导管中释放出来并膨胀及占据目标位置。该金属丝元件包括一个第一长度金属丝和一个绕第一金属丝螺旋缠绕以形成一复合对的第二长度金属丝。该复合对本身螺旋缠绕并具一定形状,以便在未受约束时占据一定空间,而当沿导管长度方向插入并受导管约束时变平直。

Description

可由导管输送的螺旋线血栓形成 装置和血栓形成方法
本发明涉及用于体内脉管系统或体腔中阻止血流的血管闭塞装置。
截断血流和/或促使血凝并且可以通过导管或其它插管引入体内的装置，对于止血或阻止出血先兆、切断向患病器官的供血、将血流引向某个器官和修复有缺陷的器官等等是很有价值的。通常采用的装置是可通过导管配置到需阻止血流的目标位置的螺旋线或颗粒。此外，可以通过导管传送多种溶液，或者有助于并加快凝血，或者处理这类医学问题。
过去通常采用的装置包括铂质螺旋线，它们可以被插入导管中并且随后利用一个普通的导管导引线或其它装置作为“柱塞”，通过导管被推到目标位置。螺旋线装置呈所需要的形状，一般为简单的螺旋形，以便在将它们送到所需位置之后，可恢复其原有形状。已有技术的铂质螺旋线装置，在将其位置保持在被运送部位经常不起作用，因而在此部位上对阻塞血流无效。过去采用的用来阻止血流的颗粒的种类，包括PVA或亲水性颗粒，当血液被吸收时，这些颗粒会膨胀变大。当然，这种膨胀有助于阻止血流，假设颗粒的位置不变。
已有技术中阻止血流的手段相当不成熟，并且在完成所需阻止血流的过程中仅仅是部分成功的。
本发明的一个目的在于提供新的和改进的血管闭塞型装置，它们可被很容易地配置在躯体中的目标位置，并且在产生凝血或阻止血流方面有效。
本发明还有一个目的在于提供这样的装置，它们制作起来容易，并且可以在尺寸和形状上被修整制作，以适应预定的配置位置。
本发明的再一个目的就是提供这样的装置，它们可以被很快而且不费力地配置在目标位置，并保持就位。
本发明的上述以及其它目的，可以在一个血栓形成装置的具体说明的实施例中被认识到，该装置包括一个穿入人体脉管系统通道到达目标位置的导管以及一个金属丝元件，该金属丝元件被绕成螺旋形并具有一定形状，当其不受约束时占据一定体积，且当沿长度方向被插入并受导管约束时拉直，以便最终从导管中释放出来以膨胀并占据目标位置。
根据本发明的一个方面，该金属丝元件被加工成朝向其远端具有逐渐变小的直径的螺旋线。根据本发明的另一个方面，靠近其远端以及远端处的较小直径的螺旋线要紧密盘绕，以便在插入血管中时能阻止血液流过它。
金属丝元件最好是一对金属丝，一个绕另一个盘绕，随后由该复合对构成更大的螺旋线。
本发明的上述以及其它目的、特征和优点，将由下面结合附图所考虑的详细描述中变得显而易见，附图中：
图1A为根据本发明原理制做的可形成血栓的螺旋线装置的部分侧剖面图；
图1B为图1A中螺旋线沿1B-1B线所取的前端视图；
图2为根据本发明原理制做的螺旋线装置的部分侧剖面图，该装置被表示成部分地配置于导管中；
图3A为根据本发明原理的金属丝复合对的一段的部分侧视图，它可构成图3B所示的螺旋线装置；
图3B为图3A所示的金属丝复合对形成的本发明的螺旋线装置的部分侧视图，以及
图4为根据本发明的螺旋线装置另一个实施例的一部分的部分侧视图。
参见图1A和1B，它们分别表示的是已被加工成螺旋线的弹性金属丝4的部分侧剖视图和端部视图。在图1A中，所表示的金属丝4被配置在血管8中。该金属丝4包括一个较大直径的部分4a和一个逐渐变窄的部分4b。在较大直径部分4a处的螺旋线膨胀接触到血管8的壁，以将螺旋线4保持就位。较窄直径部分4b用作螺旋线4的引导端或远端，便于该装置在血管中定向，并且最好更有弹性，以将插入螺旋线时对血管壁的损伤或损坏减至最小(很快就要讨论)。
例如，金属丝4可由高弹性的镍钛合金丝制成。较大螺旋线直径部分4a的直径最好为约3mm至12mm，而部分4b中的最小直径螺旋线的直径最好约为0.75mm至2mm，上述两个范围都是在螺旋线4未受约束的情况下计算得到的。
如在部分4b中使螺旋线4的直径逐渐变小，对于血流来说可提供一个更大的障碍和密集度，并因此提供了更大的阻止血流的能力，如在沿图1A中1B-1B线所取视图1B中可以清楚地看到的那样。(通过改变金属丝弹性来控制螺旋线的锥度和间隔的做法，能够将螺旋线用作一个有限泄漏阀或者一个完全闭塞物。)
图2表示被部分设置在导管12中的螺旋线4的部分侧剖面图。为了将螺旋线4配置在脉管系统通道或体内其它腔体的目标位置处，金属丝4可以大体上平直地穿过导管12，如图2所示，并随后由另一种导线(未示出)或类似装置将其推过导管，这类装置起到了柱塞的作用以迫使螺旋线弹出到导管远端以外，随后膨胀并将其在目标位置就位。当被配置在血流经过的体内目标位置处时，螺旋线4的作用是使血流减慢以产生凝血或血凝块，并且最终阻止血液进一步流动。为了有助于凝血过程，可以在设置螺旋线4的同时通过导管12以溶液的形式向目标位置输送凝血剂。此外，连在螺旋线上的纤维材料也有助于促进凝血。
图2所示螺旋线4的实施例包括一个较窄的远端部分4b，其中的螺旋线紧密缠绕至彼此相接触的程度。由于螺旋线这种高密度堆积，血流甚至在凝血或血凝块发生之前就基本上被阻止住了。
图3A和3B表示本发明的另一实施例，其包括一个中心的金属丝20和一个绕中心丝缠绕(一级螺旋线)的外围金属丝24。该金属丝的复合对随后形成了图3B所示的一个较大的螺旋线(二级螺旋线)，其中包括一个大体为圆柱形部分4a和一个圆锥形部分4b，类似于图1A所示的情况。为了在该复合对的远端部分或圆锥形部分4b获得更大的弹性，中心的金属丝20本身可以逐渐变细(或直径逐渐变小)至部分4b的一个较窄的直径，或者可以朝向其端部但未到达端部逐渐变细。当然，较窄的直径允许更大的弹性，并且可以通过控制中心丝20的直径来调整弹性度。
使中心丝20逐渐变细的一种替换方式是提供一种带有适当间隔和大小的切口的中心丝(既可以是实心的也可以是空心的)，以获得所需要的弹性。
比较有利地是，螺旋线24的直径约为0.001英寸至0.005英寸。中心丝可由镍-钛合金、不锈钢或其它适合的合金或替代物制成。
图4表示本发明的血栓形成装置的另一实施例的部分侧视图。该实施例包括一个紧密缠绕的金属丝28(一级螺旋线)，其螺旋线自身又形成一个更大的螺旋线圈(二级螺旋线)，类似于图3B的情况，但是没有中心丝。为获得较大螺旋线的可变弹性，金属丝28的直径可以变化以致于较小直径的金属丝部分比较大直径的金属丝部分具有更大的弹性。在图4中，金属丝28的直径朝向其远端28a逐渐变小。在图4所示紧密缠绕螺旋线28形成如图3B所示较大螺旋线时，具有较窄直径的螺旋线28的那部分要位于远端或图3B的部分4b处。
当然，图4的螺旋线28可以配备类似于图3A实施例中的中心丝，该中心丝可以随着金属丝28逐渐变细而适当地变细，以便沿着两者结合的长度调整弹性度。
应当理解的是，上述结构只是对本发明原理的应用的示意性说明。对于本领域普通技术人员来说，在不脱离本发明的精神实质与范畴的前提下可以做出多种改进和替换结构，而所附权利要求书试图覆盖住这些改进和结构。

Claims (15)

1.血栓形成装置，包括：
一个穿入体内脉管系统通道到达目标位置的导管，以及
一个弹性金属丝装置，被绕成螺旋形并具有一定形状，在其未受约束时占据一定空间，而当沿导管长度方向插入并受导管约束时变平直，以便最终从导管中释放出来而膨胀并占据目标位置，所述金属丝装置进一步包括：
一个第一长度的金属丝；和
一个第二长度金属丝，它绕第一金属丝螺旋缠绕以形成一复合对，所述复合对自身被螺旋缠绕并具一定形状，以便在未受约束时占据上述空间，且当沿导管长度方向插入并受导管约束时变平直。
2.如权利要求1所述的装置，其中所述第一金属丝逐渐变细以在其一远端变得更窄，并因此在该远端更具有弹性。
3.如权利要求1或2所述的装置，其中所述第二金属丝逐渐变细以在其一远端处变得更窄，并因此在该远端处更具有弹性。
4.如权利要求1所述的装置，其中所述第一金属丝朝向不到第二螺旋线一远端的位置延伸，以使复合对的一远端比复合对的其它部分更具有弹性。
5.如权利要求1所述的装置，其中所述第一金属丝包括在沿至少一部分长度方向上所选择的位置上的多个切口，以增加其弹性。
6.如权利要求1所述的装置，其中所述复合对被加工成具有朝向远端逐渐变小直径的螺旋线。
7.如权利要求6所述的装置，其中靠近和位于远端处的较小直径的螺旋线被紧密缠绕，以便在插入血管中时能阻止血液流过它。
8.血栓形成装置，包括：
一个穿入体内脉管系统通道到达目标位置的导管，以及
一个弹性金属丝装置，被绕成螺旋形并具有一定形状，在其未受约束时占据一定空间，而当沿导管长度方向插入并受导管约束时变平直，以便最终从导管中释放出来而膨胀并占据目标位置，所述金属丝装置包括一段紧密缠绕长度的金属丝，其螺旋线自身又形成一个更大的螺旋线并具有一定形状，以便在未受约束时占据上述空间，且当沿长度方向插入导管并受导管约束时变平直，该金属丝直径朝向其远端逐渐变小，因此更具弹性。
9.如权利要求8所述的装置，其中较大螺旋线直径朝向一远端逐渐变小。
10.如权利要求8所述的装置，其中所述金属丝装置是由从包括镍-钛合金和不锈钢的一组材料中选择出来的一种材料制成的。
11.如权利要求8所述的装置，其中所述金属丝装置为实心的。
12.如权利要求8所述的装置，其中所述金属丝装置为空心的，具有围绕其中心空腔的侧壁。
13.如权利要求8所述的装置，其中还包括一个被设置用来在由金属丝装置形成的螺旋线中心延伸的芯线。
14.如权利要求13所述的装置，其中芯线的直径是选择性改变的，从而使得组合起来的金属丝装置和芯线的弹性也有选择性地变化。
15.血栓形成装置，包括：
一个穿入体内脉管系统通道到达一目标位置的导管，
一个弹性金属丝装置，包括螺旋缠绕成一级螺旋线的一定长度的金属丝，该一级螺旋线本身又螺旋缠绕成一个更大的二级螺旋线，该二级螺旋线具有一定形状，以便在未受约束时占据一定空间，而当沿导管长度方向插入并受导管约束时变平直，所述金属丝装置在其一端比另一端更具弹性。
CN98105499A 1997-03-17 1998-03-16 可由导管输送的螺旋线血栓形成装置和血栓形成方法 Pending CN1244376A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US818268 1992-01-08
US08/818,268 US5800454A (en) 1997-03-17 1997-03-17 Catheter deliverable coiled wire thromboginic apparatus and method

Publications (1)

Publication Number Publication Date
CN1244376A true CN1244376A (zh) 2000-02-16

Family

ID=25225105

Family Applications (1)

Application Number Title Priority Date Filing Date
CN98105499A Pending CN1244376A (zh) 1997-03-17 1998-03-16 可由导管输送的螺旋线血栓形成装置和血栓形成方法

Country Status (12)

Country Link
US (1) US5800454A (zh)
EP (1) EP0865773B1 (zh)
JP (1) JPH10328191A (zh)
KR (1) KR19980080320A (zh)
CN (1) CN1244376A (zh)
AT (1) ATE318552T1 (zh)
AU (1) AU5933198A (zh)
CA (1) CA2232188C (zh)
DE (1) DE69833607T2 (zh)
ES (1) ES2256916T3 (zh)
SG (1) SG71767A1 (zh)
TW (1) TW381007B (zh)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100366289C (zh) * 2001-09-12 2008-02-06 维日克斯医药公司 具有固定的血小板结合剂的血管闭塞固相试剂
CN105899151A (zh) * 2013-11-29 2016-08-24 德国Pfm医用产品有限公司 将医用植入体连接到插入装置上的系统
CN117357230A (zh) * 2023-12-07 2024-01-09 上海宇度医学科技股份有限公司 一种宫腔镜下肌瘤旋转抓取器

Families Citing this family (133)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6083220A (en) 1990-03-13 2000-07-04 The Regents Of The University Of California Endovascular electrolytically detachable wire and tip for the formation of thrombus in arteries, veins, aneurysms, vascular malformations and arteriovenous fistulas
USRE42625E1 (en) 1990-03-13 2011-08-16 The Regents Of The University Of California Endovascular electrolytically detachable wire and tip for the formation of thrombus in arteries, veins, aneurysms, vascular malformations and arteriovenous fistulas
USRE41029E1 (en) 1990-03-13 2009-12-01 The Regents Of The University Of California Endovascular electrolytically detachable wire and tip for the formation of thrombus in arteries, veins, aneurysms, vascular malformations and arteriovenous fistulas
US5350397A (en) 1992-11-13 1994-09-27 Target Therapeutics, Inc. Axially detachable embolic coil assembly
US5800453A (en) * 1993-04-19 1998-09-01 Target Therapeutics, Inc. Detachable embolic coil assembly using interlocking hooks and slots
US5814062A (en) * 1994-12-22 1998-09-29 Target Therapeutics, Inc. Implant delivery assembly with expandable coupling/decoupling mechanism
US20030069522A1 (en) 1995-12-07 2003-04-10 Jacobsen Stephen J. Slotted medical device
EP0879068A4 (en) 1996-02-02 1999-04-21 Transvascular Inc METHODS AND APPARATUS FOR STOPPING BLOOD FLOW IN VESSELS
US6190402B1 (en) * 1996-06-21 2001-02-20 Musc Foundation For Research Development Insitu formable and self-forming intravascular flow modifier (IFM) and IFM assembly for deployment of same
US6156061A (en) * 1997-08-29 2000-12-05 Target Therapeutics, Inc. Fast-detaching electrically insulated implant
US5984929A (en) * 1997-08-29 1999-11-16 Target Therapeutics, Inc. Fast detaching electronically isolated implant
US6475227B2 (en) 1997-12-24 2002-11-05 Scimed Life Systems, Inc. Vaso-occlusion apparatus having a mechanically expandable detachment joint and a method for using the apparatus
US5935145A (en) 1998-02-13 1999-08-10 Target Therapeutics, Inc. Vaso-occlusive device with attached polymeric materials
US5941888A (en) 1998-02-18 1999-08-24 Target Therapeutics, Inc. Vaso-occlusive member assembly with multiple detaching points
US6077260A (en) 1998-02-19 2000-06-20 Target Therapeutics, Inc. Assembly containing an electrolytically severable joint for endovascular embolic devices
US6093199A (en) * 1998-08-05 2000-07-25 Endovascular Technologies, Inc. Intra-luminal device for treatment of body cavities and lumens and method of use
US7128073B1 (en) 1998-11-06 2006-10-31 Ev3 Endovascular, Inc. Method and device for left atrial appendage occlusion
US7044134B2 (en) 1999-11-08 2006-05-16 Ev3 Sunnyvale, Inc Method of implanting a device in the left atrial appendage
ES2555961T3 (es) * 1999-06-02 2016-01-11 Microtransform, Inc. Dispositivo oclusivo intracorpóreo
US6959470B2 (en) 1999-08-20 2005-11-01 Pigtail Fastener Company Pigtail fastener
US6434799B1 (en) * 1999-08-20 2002-08-20 Stephen D. Kuslich Pigtail fastener
US6652555B1 (en) * 1999-10-27 2003-11-25 Atritech, Inc. Barrier device for covering the ostium of left atrial appendage
US6551303B1 (en) * 1999-10-27 2003-04-22 Atritech, Inc. Barrier device for ostium of left atrial appendage
US6689150B1 (en) * 1999-10-27 2004-02-10 Atritech, Inc. Filter apparatus for ostium of left atrial appendage
US6544225B1 (en) * 2000-02-29 2003-04-08 Cordis Neurovascular, Inc. Embolic coil hydraulic deployment system with purge mechanism
US6514273B1 (en) 2000-03-22 2003-02-04 Endovascular Technologies, Inc. Device for removal of thrombus through physiological adhesion
EP1307147B1 (en) * 2000-08-11 2010-10-06 Boston Scientific Scimed, Inc. Variable softness vaso-occlusive coils
US7033374B2 (en) * 2000-09-26 2006-04-25 Microvention, Inc. Microcoil vaso-occlusive device with multi-axis secondary configuration
CA2441119A1 (en) * 2001-03-08 2002-09-19 Atritech, Inc. Atrial filter implants
DE10118017B4 (de) * 2001-04-10 2017-04-13 Dendron Gmbh Occlusionswendel und Vorrichtung zur Implantation von Occlusionswendeln
CA2449468A1 (en) * 2001-06-04 2002-12-12 Albert Einstein Healthcare Network Cardiac stimulating apparatus having a blood clot filter and atrial pacer
EP1401526B1 (en) 2001-07-05 2006-12-06 Precision Vascular Systems, Inc. Troqueable soft tip medical device and method for shaping it
US7572288B2 (en) * 2001-07-20 2009-08-11 Microvention, Inc. Aneurysm treatment device and method of use
US8715312B2 (en) * 2001-07-20 2014-05-06 Microvention, Inc. Aneurysm treatment device and method of use
US8252040B2 (en) 2001-07-20 2012-08-28 Microvention, Inc. Aneurysm treatment device and method of use
DE10233085B4 (de) 2002-07-19 2014-02-20 Dendron Gmbh Stent mit Führungsdraht
US8425549B2 (en) 2002-07-23 2013-04-23 Reverse Medical Corporation Systems and methods for removing obstructive matter from body lumens and treating vascular defects
WO2004011076A2 (en) 2002-07-25 2004-02-05 Boston Scientific Limited Medical device for navigation through anatomy and method of making same
US7914467B2 (en) 2002-07-25 2011-03-29 Boston Scientific Scimed, Inc. Tubular member having tapered transition for use in a medical device
US8377035B2 (en) 2003-01-17 2013-02-19 Boston Scientific Scimed, Inc. Unbalanced reinforcement members for medical device
US7169118B2 (en) 2003-02-26 2007-01-30 Scimed Life Systems, Inc. Elongate medical device with distal cap
US7001369B2 (en) 2003-03-27 2006-02-21 Scimed Life Systems, Inc. Medical device
US8043321B2 (en) 2003-07-24 2011-10-25 Boston Scientific Scimed, Inc. Embolic coil
US7824345B2 (en) 2003-12-22 2010-11-02 Boston Scientific Scimed, Inc. Medical device with push force limiter
WO2006032289A1 (de) 2004-09-22 2006-03-30 Dendron Gmbh Medizinisches implantat
WO2006032291A1 (de) 2004-09-22 2006-03-30 Dendron Gmbh Vorrichtung zur implantation von mikrowendeln
US8425550B2 (en) 2004-12-01 2013-04-23 Boston Scientific Scimed, Inc. Embolic coils
US7632242B2 (en) 2004-12-09 2009-12-15 Boston Scientific Scimed, Inc. Catheter including a compliant balloon
US20060155324A1 (en) * 2005-01-12 2006-07-13 Porter Stephen C Vaso-occlusive devices with attached polymer structures
US7955345B2 (en) * 2005-04-01 2011-06-07 Nexgen Medical Systems, Inc. Thrombus removal system and process
US7972359B2 (en) 2005-09-16 2011-07-05 Atritech, Inc. Intracardiac cage and method of delivering same
US9445784B2 (en) 2005-09-22 2016-09-20 Boston Scientific Scimed, Inc Intravascular ultrasound catheter
US8007509B2 (en) 2005-10-12 2011-08-30 Boston Scientific Scimed, Inc. Coil assemblies, components and methods
US7850623B2 (en) 2005-10-27 2010-12-14 Boston Scientific Scimed, Inc. Elongate medical device with continuous reinforcement member
US8101197B2 (en) 2005-12-19 2012-01-24 Stryker Corporation Forming coils
US8152839B2 (en) 2005-12-19 2012-04-10 Boston Scientific Scimed, Inc. Embolic coils
JP5230602B2 (ja) 2006-04-17 2013-07-10 タイコ ヘルスケア グループ リミテッド パートナーシップ 血管内インプラントを機械的に位置付けるためのシステムおよび方法
US8551020B2 (en) 2006-09-13 2013-10-08 Boston Scientific Scimed, Inc. Crossing guidewire
US20080269774A1 (en) 2006-10-26 2008-10-30 Chestnut Medical Technologies, Inc. Intracorporeal Grasping Device
US8414927B2 (en) 2006-11-03 2013-04-09 Boston Scientific Scimed, Inc. Cross-linked polymer particles
US8556914B2 (en) 2006-12-15 2013-10-15 Boston Scientific Scimed, Inc. Medical device including structure for crossing an occlusion in a vessel
US20170119516A1 (en) * 2007-01-31 2017-05-04 Stanley Batiste Intravenous Filter with Guidewire and Catheter Access Guide
WO2008106171A1 (en) * 2007-02-27 2008-09-04 Cook Incorporated Variable stiffness occluding device
AU2008226694B8 (en) 2007-03-13 2013-06-20 Covidien Lp An implant including a coil and a stretch-resistant member
EP2162101B1 (en) 2007-06-25 2019-02-20 MicroVention, Inc. Self-expanding prosthesis
US8409114B2 (en) 2007-08-02 2013-04-02 Boston Scientific Scimed, Inc. Composite elongate medical device including distal tubular member
US8105246B2 (en) 2007-08-03 2012-01-31 Boston Scientific Scimed, Inc. Elongate medical device having enhanced torque and methods thereof
US8821477B2 (en) 2007-08-06 2014-09-02 Boston Scientific Scimed, Inc. Alternative micromachined structures
US9808595B2 (en) 2007-08-07 2017-11-07 Boston Scientific Scimed, Inc Microfabricated catheter with improved bonding structure
US8088140B2 (en) 2008-05-19 2012-01-03 Mindframe, Inc. Blood flow restorative and embolus removal methods
US11337714B2 (en) 2007-10-17 2022-05-24 Covidien Lp Restoring blood flow and clot removal during acute ischemic stroke
US7841994B2 (en) 2007-11-02 2010-11-30 Boston Scientific Scimed, Inc. Medical device for crossing an occlusion in a vessel
JP5367721B2 (ja) 2007-12-21 2013-12-11 マイクロベンション インコーポレイテッド インプラント分離を検出するシステムおよび方法
EP2231030B1 (en) 2007-12-21 2019-02-27 MicroVention, Inc. System and method for locating detachment zone of a detachable implant
JP5457373B2 (ja) 2008-02-22 2014-04-02 コヴィディエン リミテッド パートナーシップ 血流回復のための装置
US8376961B2 (en) 2008-04-07 2013-02-19 Boston Scientific Scimed, Inc. Micromachined composite guidewire structure with anisotropic bending properties
US20100010533A1 (en) * 2008-07-11 2010-01-14 Cook Incorporated Variable strength embolization coil
US8333796B2 (en) 2008-07-15 2012-12-18 Penumbra, Inc. Embolic coil implant system and implantation method
US8535243B2 (en) 2008-09-10 2013-09-17 Boston Scientific Scimed, Inc. Medical devices and tapered tubular members for use in medical devices
US11406791B2 (en) 2009-04-03 2022-08-09 Scientia Vascular, Inc. Micro-fabricated guidewire devices having varying diameters
CN102639303B (zh) 2008-12-08 2015-09-30 血管科学有限公司 用于在产品中形成切口的微切割机
US10363389B2 (en) * 2009-04-03 2019-07-30 Scientia Vascular, Llc Micro-fabricated guidewire devices having varying diameters
US8795254B2 (en) 2008-12-10 2014-08-05 Boston Scientific Scimed, Inc. Medical devices with a slotted tubular member having improved stress distribution
US20100256603A1 (en) * 2009-04-03 2010-10-07 Scientia Vascular, Llc Micro-fabricated Catheter Devices Formed Having Elastomeric Fill Compositions
US9950137B2 (en) * 2009-04-03 2018-04-24 Scientia Vascular, Llc Micro-fabricated guidewire devices formed with hybrid materials
US20100256604A1 (en) * 2009-04-03 2010-10-07 Scientia Vascular, Llc Micro-fabricated Catheter Devices Formed Having Elastomeric Compositions
US9616195B2 (en) * 2009-04-03 2017-04-11 Scientia Vascular, Llc Micro-fabricated catheter devices having varying diameters
US9072873B2 (en) * 2009-04-03 2015-07-07 Scientia Vascular, Llc Micro-fabricated guidewire devices having elastomeric compositions
US9067333B2 (en) * 2009-04-03 2015-06-30 Scientia Vascular, Llc Micro-fabricated guidewire devices having elastomeric fill compositions
US20110046657A1 (en) * 2009-08-20 2011-02-24 Boston Scientific Scimed, Inc. Embolic Coil Introducer Catheter Locking Mechanisms
US8911487B2 (en) * 2009-09-22 2014-12-16 Penumbra, Inc. Manual actuation system for deployment of implant
US8137293B2 (en) 2009-11-17 2012-03-20 Boston Scientific Scimed, Inc. Guidewires including a porous nickel-titanium alloy
US9732321B2 (en) * 2010-02-16 2017-08-15 The General Hospital Corporation Engineered craniofacial constructs with composite scaffold
EP2552530A1 (en) 2010-03-31 2013-02-06 Boston Scientific Scimed, Inc. Guidewire with a flexural rigidity profile
WO2011130081A1 (en) 2010-04-14 2011-10-20 Microvention, Inc. Implant delivery device
US9039749B2 (en) 2010-10-01 2015-05-26 Covidien Lp Methods and apparatuses for flow restoration and implanting members in the human body
US8795202B2 (en) 2011-02-04 2014-08-05 Boston Scientific Scimed, Inc. Guidewires and methods for making and using the same
WO2012155093A1 (en) 2011-05-11 2012-11-15 Microvention, Inc. Device for occluding a lumen
US9072874B2 (en) 2011-05-13 2015-07-07 Boston Scientific Scimed, Inc. Medical devices with a heat transfer region and a heat sink region and methods for manufacturing medical devices
US9579104B2 (en) 2011-11-30 2017-02-28 Covidien Lp Positioning and detaching implants
US9011480B2 (en) * 2012-01-20 2015-04-21 Covidien Lp Aneurysm treatment coils
US9687245B2 (en) 2012-03-23 2017-06-27 Covidien Lp Occlusive devices and methods of use
EP2854700B1 (en) 2012-05-31 2021-07-07 Javelin Medical Ltd. Devices for embolic protection
JPWO2014058043A1 (ja) * 2012-10-12 2016-09-05 日本発條株式会社 生体内留置部材、ステント、塞栓部材、血管拡張キット及び動脈瘤塞栓キット
CN105007864B (zh) 2013-01-18 2017-03-22 标枪医疗有限公司 单丝植入物和用于递送单丝植入物的系统
US9844383B2 (en) 2013-05-08 2017-12-19 Embolx, Inc. Devices and methods for low pressure tumor embolization
JP6401781B2 (ja) 2013-05-08 2018-10-10 エンボルクス, インク.Embolx, Inc. 一体型流量調整による経血管的腫瘍塞栓形成の装置及び方法
US10076399B2 (en) 2013-09-13 2018-09-18 Covidien Lp Endovascular device engagement
US9592110B1 (en) 2013-12-06 2017-03-14 Javelin Medical, Ltd. Systems and methods for implant delivery
US9901706B2 (en) 2014-04-11 2018-02-27 Boston Scientific Scimed, Inc. Catheters and catheter shafts
US9713475B2 (en) 2014-04-18 2017-07-25 Covidien Lp Embolic medical devices
US11351048B2 (en) 2015-11-16 2022-06-07 Boston Scientific Scimed, Inc. Stent delivery systems with a reinforced deployment sheath
WO2017086479A1 (ja) * 2015-11-19 2017-05-26 株式会社カネカ 生体内留置部材及び該生体内留置部材を備える生体内留置部材配置装置
US9550046B1 (en) 2016-02-16 2017-01-24 Embolx, Inc. Balloon catheter and methods of fabrication and use
US11464948B2 (en) 2016-02-16 2022-10-11 Embolx, Inc. Balloon catheters and methods of manufacture and use
US10350382B1 (en) 2018-06-08 2019-07-16 Embolx, Inc. High torque catheter and methods of manufacture
US11207502B2 (en) 2016-07-18 2021-12-28 Scientia Vascular, Llc Guidewire devices having shapeable tips and bypass cuts
US11052228B2 (en) 2016-07-18 2021-07-06 Scientia Vascular, Llc Guidewire devices having shapeable tips and bypass cuts
US10821268B2 (en) 2016-09-14 2020-11-03 Scientia Vascular, Llc Integrated coil vascular devices
JP7222886B2 (ja) * 2016-10-21 2023-02-15 ジャベリン メディカル リミテッド 塞栓防止用システム、方法、およびデバイス
US11452541B2 (en) 2016-12-22 2022-09-27 Scientia Vascular, Inc. Intravascular device having a selectively deflectable tip
US11432809B2 (en) 2017-04-27 2022-09-06 Boston Scientific Scimed, Inc. Occlusive medical device with fabric retention barb
EP3609563B1 (en) 2017-05-26 2021-03-24 Scientia Vascular, LLC Micro-fabricated medical device having a non-helical cut arrangement
WO2019164877A1 (en) 2018-02-20 2019-08-29 Boston Scientific Scimed, Inc. Medical device release system
US11305095B2 (en) 2018-02-22 2022-04-19 Scientia Vascular, Llc Microfabricated catheter having an intermediate preferred bending section
CN112714632A (zh) 2018-08-21 2021-04-27 波士顿科学医学有限公司 用于心血管设备的带有倒钩的突出构件
US10912569B2 (en) * 2018-08-22 2021-02-09 Covidien Lp Aneurysm treatment coils and associated systems and methods of use
US10905432B2 (en) * 2018-08-22 2021-02-02 Covidien Lp Aneurysm treatment coils and associated systems and methods of use
WO2020123791A1 (en) * 2018-12-12 2020-06-18 Naamira Biomedicals Llc. Multipurpose wearable endovascular apparatus
WO2021011694A1 (en) 2019-07-17 2021-01-21 Boston Scientific Scimed, Inc. Left atrial appendage implant with continuous covering
US11399840B2 (en) 2019-08-13 2022-08-02 Covidien Lp Implantable embolization device
CN114340516A (zh) 2019-08-30 2022-04-12 波士顿科学医学有限公司 带密封盘的左心房附件植入物
US11903589B2 (en) 2020-03-24 2024-02-20 Boston Scientific Scimed, Inc. Medical system for treating a left atrial appendage

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4994069A (en) * 1988-11-02 1991-02-19 Target Therapeutics Vaso-occlusion coil and method
DE4104702C2 (de) * 1991-02-15 1996-01-18 Malte Neuss Implantate für Organwege in Wendelform
US5217484A (en) * 1991-06-07 1993-06-08 Marks Michael P Retractable-wire catheter device and method
WO1995025480A1 (en) * 1994-03-18 1995-09-28 Cook Incorporated Helical embolization coil
US5645558A (en) * 1995-04-20 1997-07-08 Medical University Of South Carolina Anatomically shaped vasoocclusive device and method of making the same
US5639277A (en) * 1995-04-28 1997-06-17 Target Therapeutics, Inc. Embolic coils with offset helical and twisted helical shapes
DE69630898T2 (de) * 1995-06-30 2004-08-26 Boston Scientific Ltd., Saint Michael Ausdehnungswiderstandsfähige vaso-okklusive Spirale
US5582619A (en) * 1995-06-30 1996-12-10 Target Therapeutics, Inc. Stretch resistant vaso-occlusive coils
US5649949A (en) * 1996-03-14 1997-07-22 Target Therapeutics, Inc. Variable cross-section conical vasoocclusive coils

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100366289C (zh) * 2001-09-12 2008-02-06 维日克斯医药公司 具有固定的血小板结合剂的血管闭塞固相试剂
CN105899151A (zh) * 2013-11-29 2016-08-24 德国Pfm医用产品有限公司 将医用植入体连接到插入装置上的系统
CN105899151B (zh) * 2013-11-29 2019-11-22 德国Pfm医用产品有限公司 将医用植入体连接到插入装置上的系统
CN117357230A (zh) * 2023-12-07 2024-01-09 上海宇度医学科技股份有限公司 一种宫腔镜下肌瘤旋转抓取器
CN117357230B (zh) * 2023-12-07 2024-03-12 上海宇度医学科技股份有限公司 一种宫腔镜下肌瘤旋转抓取器

Also Published As

Publication number Publication date
DE69833607D1 (de) 2006-04-27
JPH10328191A (ja) 1998-12-15
EP0865773A1 (en) 1998-09-23
ATE318552T1 (de) 2006-03-15
ES2256916T3 (es) 2006-07-16
AU5933198A (en) 1998-09-17
DE69833607T2 (de) 2007-02-08
EP0865773B1 (en) 2006-03-01
TW381007B (en) 2000-02-01
US5800454A (en) 1998-09-01
SG71767A1 (en) 2000-04-18
CA2232188A1 (en) 1998-09-17
CA2232188C (en) 2005-11-29
KR19980080320A (ko) 1998-11-25

Similar Documents

Publication Publication Date Title
CN1244376A (zh) 可由导管输送的螺旋线血栓形成装置和血栓形成方法
US5911717A (en) Catheter deliverable thrombogenic apparatus and method
US6776788B1 (en) Embolization device for positioning in a blood vessel
US5649949A (en) Variable cross-section conical vasoocclusive coils
US6241691B1 (en) Coated superelastic stent
JP2908363B2 (ja) 生物活性閉塞コイル
JPH07148264A (ja) マイクロカテーテル
EP1698284A1 (en) Embolic coil with twisted wire
JP2013524943A (ja) 神経血管用途用の薄型誘導カテーテル
JPH0751378A (ja) 圧力流体管路を有するカテーテルとこれを製造する方法
JPH08508927A (ja) 血栓形成性強化繊維を備える血管閉塞コイル
US20130066359A1 (en) Vaso-occlusive device
CN113995551A (zh) 血流导向支架及系统
CN218247493U (zh) 血流导向支架
CN114469232A (zh) 一种血管塞
CN211460698U (zh) 一种输送导丝及治疗装置
CN217548136U (zh) 弹簧圈及栓塞装置
CN220632154U (zh) 血流导向栓塞支架
US20200078024A1 (en) Embolization coil with end coil integrated within main coil
JPH1057495A (ja) バルーンカテーテル
CN116602724A (zh) 血流导向栓塞支架

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C53 Correction of patent of invention or patent application
CB02 Change of applicant information

Applicant after: Precision Vascular Systems, Inc.

Applicant before: Sarcos, Inc.

COR Change of bibliographic data

Free format text: CORRECT: APPLICANT; FROM: SARCOS, INC. TO: PRECISE TUBE SYSTEM CORP.

C02 Deemed withdrawal of patent application after publication (patent law 2001)
WD01 Invention patent application deemed withdrawn after publication
REG Reference to a national code

Ref country code: HK

Ref legal event code: WD

Ref document number: 1024399

Country of ref document: HK