CN104905835A - 3D (three-dimensional) printed stitch-free pancreatico-duodenectomy stent and manufacturing method thereof - Google Patents
3D (three-dimensional) printed stitch-free pancreatico-duodenectomy stent and manufacturing method thereof Download PDFInfo
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- CN104905835A CN104905835A CN201510330190.8A CN201510330190A CN104905835A CN 104905835 A CN104905835 A CN 104905835A CN 201510330190 A CN201510330190 A CN 201510330190A CN 104905835 A CN104905835 A CN 104905835A
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- Prior art keywords
- stent
- support tube
- duodenectomy
- pancreatico
- sew
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/11—Surgical instruments, devices or methods, e.g. tourniquets for performing anastomosis; Buttons for anastomosis
- A61B17/1114—Surgical instruments, devices or methods, e.g. tourniquets for performing anastomosis; Buttons for anastomosis of the digestive tract, e.g. bowels or oesophagus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/11—Surgical instruments, devices or methods, e.g. tourniquets for performing anastomosis; Buttons for anastomosis
- A61B2017/1135—End-to-side connections, e.g. T- or Y-connections
Abstract
The invention discloses a 3D (three-dimensional) printed stitch-free pancreatico-duodenectomy stent. The 3D printed stitch-free pancreatico-duodenectomy stent made of a degradable biological material by a 3D printing technology comprises a stent duct and protrusive spines protruding over the outer wall of the stent duct, a protrusive head is integrally connected with one end of the stent duct, and holes are formed in the wall of the stent duct. The manufacturing method of the 3D printed stitch-free pancreatico-duodenectomy stent includes the steps of (1) measuring the diameter of a pancreatic duct of a patient needing a hepatopancreat and obiliary reconstructive operation through CT (computed tomography); (2) according to a CT thin layer scanning result, acquiring needed 3D printing data through algorithmic conversion and image processing, designing the spines and the protrusive head structure on the pancreatico-duodenectomy contact face; (3) using the most precise 3D printer and the biological and degradable material to print the 3D pancreatico-duodenectomy stent which is applied to stitch-free pancreatico-duodenectomy. The 3D printed stitch-free pancreatico-duodenectomy stent has the advantages of simple structure, convenience in use, remarkable effect and capability of achieving stitch-free pancreatico-duodenectomy, the risks of leakage and narrowness are reduced, and operating difficulty and risks are reduced greatly.
Description
Technical field
The present invention relates to medical operating articles for use technical field, belong to one 3D printing and exempt to sew up pancreas duct jejunum anastomotic scaffold and preparation method.
Background technology
It is complicated that tradition opens the operation of abdomen pancreaticoduodenectomy, operation wound is large, and biliary enteric anastomosis, Pancreaticoenterostomy are the committed steps of pancreaticoduodenectomy, because Cholangio-jejunostomy mouth or (with pancreas intestinal anastomotic stoma) Cholangio-jejunostomy mouth fistula, the Pancreaticojejunostomy entirely do not caused that heal is postoperative common severe complication, general incidence rate is 5 ~ 20%, Pancreaticojejunostomy mortality rate can reach 20 ~ 40%, and medical expense is expensive.
In recent years, domestic and international minority comprehensive large hospital peritoneoscope or the large case report of Leonardo da Vinci's robotic surgical device (Wicresoft) pancreaticoduodenectomy show, Wicresoft's pancreaticoduodenectomy opens abdomen pancreaticoduodenectomy than tradition, not only post-operative recovery is significantly accelerated, and postoperative short-term, long term survival rate are even better.But Wicresoft's advantage of peritoneoscope and Leonardo da Vinci robot pancreaticoduodenectomy, do not accepted extensively by outer scientific cirle, its main cause is peritoneoscope pancreaticoduodenectomy Cholangio-jejunostomy, the complexity of pancreas Surgical healing and technical difficulty, makes operating time significant prolongation; Our experience shows: especially as ductus pancreaticus diameter <3mm or marginality ductus pancreaticus, ductus pancreaticus is implemented very difficult to mucosa anastomosis under peritoneoscope, the probability of postoperative generation pancreas fistula significantly rises, pancreas Digestive system contact methods of anastomosis have to be selected (as binding pancreas intestinal/pancreas stomach, pancreas intestinal side or end end, pancreas stomach embedding inosculating,), thus increase the complication such as postoperative digestive tract hemorrhage; The technical bottleneck be difficult under although Leonardo da Vinci robot amplifies 10 times of surgical field of view by its three-dimensional and interior wrist breaches peritoneoscope flexibly, shorten the identical time, but, domestic only have 26 machines, and judgement that whether suture is definitely strained becomes very difficult during the disappearance of tactile feedback makes to coincide, tension can be broken suture or cut and organize, and crossing pine can cause fistula of operative incision, and reported literature also confirms peritoneoscope and robot postoperative pancreatic fistula, the incidence rate of leak does not significantly reduce.Therefore not only traditional pancreaticoduodenectomy biliary enteric anastomosis, Pancreaticoenterostomy remain a Research Challenges and focus, and in current Wicresoft, precisely, epoch of effective liver and gall pancreas surgery development, peritoneoscope and Leonardo da Vinci robot biliary enteric anastomosis, Pancreaticoenterostomy research and innovation are significantly more urgent.
The biliary enteric anastomosis of current clinical practice, Pancreaticoenterostomy be all set up with sew up, on the basis of tie a knot, the mode of optimal reconstruction of digestive tract has a kind of methods of anastomosis, can exempt the operation that these are relevant with stitching.Sew up nature and have pinprick, the elasticity of knotting, the tearing of organizational structure, the defects such as the prolongation of operating time.Utilize a kind of support, rear connection is inserted at the two ends of intending coincideing separately and can fixes, two broken ends of fractured bone self-growths connect, so both stitching can be exempted, avoid that the technical bottleneck being difficult to overcome all is existed to peritoneoscope or Leonardo da Vinci, ensure that the unobstructed of anastomotic stoma by support again, avoid the complication that may cause because of anastomotic stoma edema or identical defect.Research in the past have also been made a lot of trial in this respect, but what also do not have molding so far can the product of clinical practice, reason is that Cholangio-jejunostomy, pancreas Surgical healing are unlike gastrointestinal anastomosis, gastrointestinal anastomosis is because tissue plasticity is strong, anastomotic stoma size is relatively fixing, anastomotic stoma large, therefore clinically generally applies anastomat; And the shape and size of biliary tract, ductus pancreaticus and bore, because disease character, stadium difference are widely different, and ductus pancreaticus, bile duct poor plasticity, caliber is little, therefore, the anastomosis ring that the bore having fixed mould to produce as gastrointestinal anastomosis device is consistent or anastomat, and be not suitable for clinical.Cross and slightly easily make it strut excessively and affect Tissue Blood confession, mistake detailed rules and regulations can cause fixes loosely.
Summary of the invention
The object of this invention is to provide one 3D printing to exempt to sew up pancreas duct jejunum anastomotic scaffold and preparation method, its structure is simple, easy to use, Be very effective, it is according to the reconstruction of preoperative image data data, can print with individual patients bile duct size to the biliary duct jejunum anastomotic scaffold mated with 3D printing technique, by these two ends with plush copper and the pipe outer wall support tube with projection, can realize exempting from sutured anastomosis, thus decrease Lou and narrow risk, greatly reduce operation easier and risk simultaneously.
For achieving the above object, the present invention takes following technical scheme:
One 3D prints and exempts to sew up pancreas duct jejunum anastomotic scaffold, it is characterized in that: the convex thorn that this pancreas duct jejunum anastomotic scaffold comprises support tube and protrudes at support tube outer wall, plush copper is connected with in one end of this support tube, the tube wall of this support tube is provided with hole, be connected with drainage tube in the outside of this plush copper, this biliary duct jejunum anastomotic scaffold makes with degradable biomaterial 3D printing technique.
Wherein, described plush copper, spherical in semicircle, the outside side of arc surface.
Wherein, be laid with the convex thorn of three rows, often arrange convex thorn and be evenly equipped with four at support tube outer wall, the described convex support tube that stabs does not have plush copper end to tilt.
Wherein, be laid with the convex thorn of three rows, often arrange convex thorn and be evenly equipped with four at support tube outer wall, the described convex support tube that stabs is provided with plush copper end.
Wherein, be laid with the convex thorn of three rows, often arrange convex thorn and be evenly equipped with four at support tube outer wall, the described convex support tube outer wall vertical direction that stabs is arranged.。
3D prints the preparation method exempting to sew up pancreas duct jejunum anastomotic scaffold, and it comprises the following steps:
(1) the ductus pancreaticus diameter needing liver and gall pancreas reconstruction operations patient, is measured by CT;
(2), according to the result of bile duct CT thin slice scan, by the conversion of algorithm and the process of image, obtain the 3D print data needed, and identical contact surface is designed convex thorn and plush copper structure;
(3) the most accurate 3D printer at present, is used, the degradation material of applying biological compatibility, printing produces 3D pancreas duct jejunum anastomotic scaffold, namely formed individuation with the similar pancreas duct jejunum anastomotic scaffold of micro-structure of exempting to sew up, pancreas duct jejunum anastomotic scaffold is applied to respectively and exempts to sew up Cholangio-jejunostomy.
Wherein, described degradation material comprises: biocompatible materials or degradable biomaterial, and wherein biocompatible materials is silica gel.
The pancreas duct jejunum anastomotic scaffold of individuation degradation material is manufactured with 3D printing technique, when carrying out robot and peritoneoscope pancreas Surgical healing, release is sewed up, make to coincide simply, anastomotic stoma need not be sewed up, greatly save the time, pancreas duct jejunum anastomotic scaffold effectively prevent the direct effect of Digestive system to anastomotic stoma simultaneously, exempt from suturing skill and also ensure that anastomotic stoma has sufficient blood to supply, also be suitable for bile duct or the ductus pancreaticus broken ends of fractured bone to dissociate the hilar bile duct of difficulty, stones in intrahepatic bile duct and the heavier case of pancreas inflammatory, pancreas duct jejunum anastomotic scaffold can also ensure the unobstructed of anastomotic stoma, avoid anastomotic stoma because of scar hyperplasia, the anastomotic stricture that cicatricial contracture causes, improve the late result of pancreas Surgical healing.Thus be expected to solve peritoneoscope and the key difficulties problem of Leonardo da Vinci robot in pancreas Surgical healing, make that operation is safer simple and conveniently to be carried out, improve the therapeutic effect relating to the complicated liver and gall pancreas Minimally Invasive Surgery of above-mentioned surgery reconstruction of digestive tract.
The invention has the beneficial effects as follows: its structure is simple, easy to use, Be very effective, it is according to the reconstruction of preoperative image data data, can print with individual patients ductus pancreaticus size to the pancreas duct jejunum anastomotic scaffold pipe mated with 3D printing technique, by these support tubes with convex thorn and plush copper, can realize exempting from sutured anastomosis, thus decrease Lou and narrow risk, greatly reduce operation easier and risk simultaneously.
Accompanying drawing explanation
Fig. 1 is the structural representation of the embodiment of the present invention 1.
Fig. 2 is the A-A cross-sectional schematic of Fig. 1.
Fig. 3 is the structural representation of the embodiment of the present invention 2.
Fig. 4 is the structural representation of the embodiment of the present invention 3.
Fig. 5 is the schematic diagram that the present invention is used in when pancreas intestinal (ductus pancreaticus is to intestinal anastomosis) coincide.
Drawing reference numeral: 1, pancreas duct jejunum anastomotic scaffold; 2, support tube; 3, convex thorn; 4, hole; 5, plush copper; 6, drainage tube.
Detailed description of the invention
Shown in Fig. 1, Fig. 2, embodiment 1: one 3D prints and exempts to sew up pancreas duct jejunum anastomotic scaffold, the convex thorn 3 that this pancreas duct jejunum anastomotic scaffold 1 comprises support tube 2 and protrudes at support tube outer wall, plush copper 5 is connected with in one end of this support tube 2, the tube wall of this support tube 2 is provided with hole 4, the effect in hole 4 is that pancreatic juice drainage is entered drainage tube, is connected with drainage tube 6 in the outside of this plush copper 5, and this biliary duct jejunum anastomotic scaffold 1 makes with degradable biomaterial 3D printing technique.
Wherein, described plush copper 5, spherical in semicircle, the outside side of arc surface.
Wherein, be laid with the convex thorn 3 of three rows, often arrange convex thorn 3 and be evenly equipped with four at support tube 2 outer wall, the described convex support tube 2 that stabs does not have plush copper end to tilt.
Shown in Figure 3, embodiment 2:, be laid with the convex thorn 3 of three rows at support tube 2 outer wall, often arrange convex thorn and be evenly equipped with four, described convex thorn 3 is provided with plush copper 5 end to support tube.
Shown in Figure 4, embodiment 3: be laid with the convex thorn 3 of three rows at support tube 2 outer wall, often arrange convex thorn and be evenly equipped with four, described convex thorn 3 is arranged to support tube outer wall vertical direction.。
3D prints the preparation method exempting to sew up pancreas duct jejunum anastomotic scaffold, and it comprises the following steps:
(1) the ductus pancreaticus diameter needing liver and gall pancreas reconstruction operations patient, is measured by CT;
(2), according to the result of bile duct CT thin slice scan, by the conversion of algorithm and the process of image, obtain the 3D print data needed, and identical contact surface is designed convex thorn and plush copper structure;
(3) the most accurate 3D printer at present, is used, the degradation material of applying biological compatibility, printing produces 3D pancreas duct jejunum anastomotic scaffold, namely formed individuation with the similar pancreas duct jejunum anastomotic scaffold of micro-structure of exempting to sew up, pancreas duct jejunum anastomotic scaffold is applied to respectively and exempts to sew up Cholangio-jejunostomy.
Wherein, described degradation material comprises: biocompatible materials or degradable biomaterial, and wherein biocompatible materials is silica gel.
See Fig. 5 be the present invention be used in pancreas intestinal (ductus pancreaticus is to intestinal anastomosis) coincide time schematic diagram, during use, under the help of peritoneoscope and Leonardo da Vinci robot, pancreas duct jejunum anastomotic scaffold 1 is inserted in jejunum and ductus pancreaticus stump respectively, relies on the plush copper 5 of support tube one end and convex thorn 3 to play the object preventing slip mutually; After jejunum and ductus pancreaticus stump coincide gradually, pancreas duct jejunum anastomotic scaffold 1 is degraded gradually.
The above know-why being preferred embodiment of the present invention and using; for those skilled in the art or surgeon;; when not deviating from the spirit and scope of the present invention; any based on apparent changes such as the equivalent transformation on technical solution of the present invention basis, simple replacements, all belong within scope.
Claims (7)
1. exempt to sew up pancreas duct jejunum anastomotic scaffold with 3D printing for one kind, it is characterized in that: the convex thorn that this pancreas duct jejunum anastomotic scaffold comprises support tube and protrudes at support tube outer wall, plush copper is connected with in one end of this support tube, the tube wall of this support tube is provided with hole, be connected with drainage tube in the outside of this plush copper, this biliary duct jejunum anastomotic scaffold makes with degradable biomaterial 3D printing technique.
2. 3D according to claim 1 prints and exempts to sew up biliary duct jejunum anastomotic scaffold, it is characterized in that: described plush copper, spherical in semicircle, the outside side of arc surface.
3. 3D according to claim 1 and 2 prints and exempts to sew up biliary duct jejunum anastomotic scaffold, and it is characterized in that: be laid with the convex thorn of three rows at support tube outer wall, often arrange convex thorn and be evenly equipped with four, the described convex support tube that stabs does not have plush copper end to tilt.
4. 3D according to claim 1 and 2 prints and exempts to sew up biliary duct jejunum anastomotic scaffold, it is characterized in that: be laid with the convex thorn of three rows at support tube outer wall, often arrange convex thorn and be evenly equipped with four, and the described convex support tube that stabs is provided with plush copper end.
5. 3D according to claim 1 and 2 prints and exempts to sew up biliary duct jejunum anastomotic scaffold, it is characterized in that: be laid with the convex thorn of three rows at support tube outer wall, often arrange convex thorn and be evenly equipped with four, and the described convex support tube outer wall vertical direction that stabs is arranged.
6. print the preparation method exempting to sew up pancreas duct jejunum anastomotic scaffold with 3D, it comprises the following steps:
(1) the ductus pancreaticus diameter needing liver and gall pancreas reconstruction operations patient, is measured by CT;
(2), according to the result of bile duct CT thin slice scan, by the conversion of algorithm and the process of image, obtain the 3D print data needed, and identical contact surface is designed convex thorn and plush copper structure;
(3) the most accurate 3D printer at present, is used, the degradation material of applying biological compatibility, printing produces 3D pancreas duct jejunum anastomotic scaffold, namely formed individuation with the similar pancreas duct jejunum anastomotic scaffold of micro-structure of exempting to sew up, pancreas duct jejunum anastomotic scaffold is applied to respectively and exempts to sew up Cholangio-jejunostomy.
7. 3D according to claim 6 prints the preparation method exempting to sew up pancreas duct jejunum anastomotic scaffold, and it is characterized in that: described degradation material comprises: biocompatible materials or degradable biomaterial, wherein biocompatible materials is silica gel.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510330190.8A CN104905835A (en) | 2015-06-15 | 2015-06-15 | 3D (three-dimensional) printed stitch-free pancreatico-duodenectomy stent and manufacturing method thereof |
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| CN201510330190.8A CN104905835A (en) | 2015-06-15 | 2015-06-15 | 3D (three-dimensional) printed stitch-free pancreatico-duodenectomy stent and manufacturing method thereof |
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| CN104905835A true CN104905835A (en) | 2015-09-16 |
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105559837A (en) * | 2015-12-14 | 2016-05-11 | 洪德飞 | Pancreas-intestine external drainage silicone III pancreas-intestine stent |
| CN106859716A (en) * | 2017-03-02 | 2017-06-20 | 福建医科大学附属协和医院 | A kind of pancreas intestine anastomat |
| CN108992116A (en) * | 2018-08-27 | 2018-12-14 | 杭州市第人民医院 | A kind of pancreas Surgical healing support hangnail pipe |
| CN110522483A (en) * | 2018-09-14 | 2019-12-03 | 复旦大学附属华山医院 | Ductus pancreaticus is to jejunal mucous membrane anastomosis bracket |
| CN113693680A (en) * | 2021-09-01 | 2021-11-26 | 南微医学科技股份有限公司 | Biliary stent |
| WO2024021389A1 (en) * | 2022-07-25 | 2024-02-01 | 中南大学 | Pancreatin inactivation stent drainage tube and preparation method therefor |
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| CN203042350U (en) * | 2013-01-18 | 2013-07-10 | 爱宝骨科有限公司 | Medical degradable magnesium alloy stapling canula |
| CN204931761U (en) * | 2015-06-15 | 2016-01-06 | 洪德飞 | Print with 3D and exempt to sew up pancreas duct jejunum anastomotic scaffold |
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| US20090093837A1 (en) * | 2007-10-09 | 2009-04-09 | Wilson-Cook Medical Inc. | Anastomosis plug for bariatric surgery |
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Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105559837A (en) * | 2015-12-14 | 2016-05-11 | 洪德飞 | Pancreas-intestine external drainage silicone III pancreas-intestine stent |
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| CN108992116A (en) * | 2018-08-27 | 2018-12-14 | 杭州市第人民医院 | A kind of pancreas Surgical healing support hangnail pipe |
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| WO2024021389A1 (en) * | 2022-07-25 | 2024-02-01 | 中南大学 | Pancreatin inactivation stent drainage tube and preparation method therefor |
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Application publication date: 20150916 |