CN104548381A

CN104548381A - Soft-foundation conformal uniform light irradiation photodynamics therapy device

Info

Publication number: CN104548381A
Application number: CN201510055034.5A
Authority: CN
Inventors: 何林欢; 胡晓明
Original assignee: Beijing Institute of Technology BIT
Current assignee: Beijing Institute of Technology BIT
Priority date: 2015-02-03
Filing date: 2015-02-03
Publication date: 2015-04-29

Abstract

The invention relates to a soft-foundation conformal uniform light irradiation photodynamics therapy device. Area of a treated patient is acquired by performing three-dimensional reconstruction on a body surface focus area, a contact face is made by a high-transparency soft-foundation material such as flexible silica gel, and therapy light is guided in by optical fibers and uniformly distributed by a light uniformizing plate and transparent liquid. The soft-foundation conformal uniform light irradiation photodynamics therapy device can be accurately fitted with the focus area, number of the optical fibers, power of the therapy light and wavelength of the therapy light can be changed according to therapy needs, different requirements on body surface photodynamics therapy are met, and therapy effect is improved.

Description

The conformal uniform illumination of a kind of soft base penetrates optical power therapentic equipment

Technical field

The present invention relates to a kind of soft base, conformal uniform illumination penetrates optical power therapentic equipment, be applicable to the optical dynamic therapy of skin surface disease contact irradiation, such as nevus flammeus, seat skin ulcer etc.

Technical background

Photodynamic therapy (PDT) utilizes photosensitizer and special wavelength light to carry out radiation to produce photodynamic reaction, i.e. a series of photochemical reaction, its reaction product (excited state singlet oxygen molecular) has extremely strong oxidisability, the cell of pathological changes around can be killed, and then reach a kind of new technique of therapeutic purposes, compare Traditional regimen, PDT has the advantages such as side effect is little, toxicity is low, the selection suitability is good, Wicresoft.

Optical dynamic therapy has three key influence factors: photosensitizer, the oxygen molecule in light source and cell.The light source of current various optical dynamic therapy instrument is fixed on hard substrate mostly, can not carry out corresponding bending adjustment according to treatment requirement.Thus the optical power density causing different parts or different curvature different angles focal area, same position to receive is different, as face, and cervical region.Treatment light source can not irradiate the focal area skin of different curvature direction different angles by Vertical Uniform simultaneously, and in focal zone, skin receives the optical power density differed greatly, and high degree affects therapeutic effect.In addition, because treatment light belt has higher energy in optical dynamic therapy process, therapentic part can be made to generate heat, patient is allowed slightly to feel uncomfortable, this device adopts high transparency liquid to do light propagation medium not only can improve the uniformity for the treatment of illumination, also can reduce focal area temperature, alleviate patient's misery over the course for the treatment of.

Summary of the invention

The present invention is a kind of optical power therapentic equipment of skin surface disease, can realize treating the uniform irradiation of light in each locality of focal area by described device combination.

Technical scheme of the present invention is: use three-dimensional reconstruction system to carry out to focal area area and the shape that three-dimensional reconstruction determines focal area, the plane of corresponding size is obtained after three-dimensional is launched, the hard plate that high transparency flexible material plates reflective membrane in conjunction with even tabula rasa and inner surface is formed former and later two enclosed cavities, and high transparency liquid is full of in front cavity, treatment light source is imported by optical fiber, after optical fiber connector inserts therapy equipment, cavity is interior apart from even tabula rasa suitable distance, according to coincident with severity degree of condition, rear cavity cap can manufacture the plate of different hole number, to insert the optical fiber of varying number, the treatment light importing different optical power density is treated.

Accompanying drawing explanation

Fig. 1 is the treatment figure of this optical power therapentic equipment

Fig. 2 is the three-dimensional structure diagram of this device

Be the front view of this device on the left of Fig. 3, right side is the profile of front view along A-----A.

In Fig. 21 for optical fiber, 2-1 be even tabula rasa, 2-2 is high transparency liquid, 2-3 is high transparency flexible material

Specific embodiments

As shown in Figure 1, first the plain structural model of focal area is obtained according to the Three-dimension Reconstruction Model of three-dimensional reconstruction system to patient focal area, choose suitable (2-3) high transparency flexible material, the contact surface closed cavity identical with focal area size is made into the baffle plate of inner surface plating reflective membrane in conjunction with (2-1) even tabula rasa, (2-2) high transparency liquid is filled in front cavity, in order to cavity before improving therapeutic effect requirement fill liquid after can not have bubble, (1) optical fiber of respective numbers is selected to import the treatment light source of respective wavelength according to Treatment need, to be inserted on bonnet (1) optical fiber connector from (2-1) even tabula rasa correct position place.(2-3) high transparency flexible material has covered body surface focal area just, what enable treatment light Vertical Uniform is incident upon on focal area, illumination Density Distribution in area for treatment is even, use (2-2) high transparency liquid simultaneously, conversion efficiency can be made even, can lower the temperature to focal area again, make therapeutic process more comfortable.

The above is only embodiments of the invention, not does any pro forma restriction to structure of the present invention.Every above embodiment is done according to technical spirit of the present invention any simple modification, equivalent variations and modification, all still belong in the scope of technical scheme of the present invention.

Claims

1. the conformal uniform illumination of soft base penetrates an optical power therapentic equipment, it is characterized in that to carry out according to the size of body surface focal area and the order of severity adjustment that adapts, and contact surface can be fitted focal area completely, treatment light uniform irradiation focal area.

2. penetrate optical power therapentic equipment according to the conformal uniform illumination of the soft base of the one in claim 1, it is characterized in that being made up of the contour transparent soft host material of flexible silica gel with body surface contact surface.

3. penetrate optical power therapentic equipment according to the conformal uniform illumination of the soft base of the one in claim 1, it is characterized in that treatment light source is imported by device rear portion through optical fiber, number of fibers and optical source wavelength can be determined by disease severity.

4. penetrate optical power therapentic equipment according to the conformal uniform illumination of the soft base of the one in claim 1, after it is characterized in that the even photosystem that treatment light source need form through even tabula rasa and high transparency liquid, could area for treatment be arrived.