CN103800023A - Double-panel imaging device based on continuous crystals - Google Patents
Double-panel imaging device based on continuous crystals Download PDFInfo
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- CN103800023A CN103800023A CN201410056890.8A CN201410056890A CN103800023A CN 103800023 A CN103800023 A CN 103800023A CN 201410056890 A CN201410056890 A CN 201410056890A CN 103800023 A CN103800023 A CN 103800023A
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Abstract
The invention discloses a double-panel imaging device based on continuous crystals. The double-panel imaging device comprises two detection modules. The detection modules comprise the continuous crystals, photovoltaic conversion parts and array read-out electronics systems, wherein the photovoltaic conversion parts are next to the continuous crystals, and the array read-out electronics systems are connected with the photovoltaic conversion parts. According to the double-panel imaging device, the double-panel structure is adopted, the continuous crystals are adopted in the detection modules, the depth effect is effectively avoided, no detection dead zones exist, detection efficiency and detection sensitivity can be improved, and then imaging accuracy and reliability are improved.
Description
Technical field
The present invention relates to molecular imaging field, be specifically related to two flat panel imaging devices.
Background technology
Nucleus medical image technology can reflect by the mode of image the metabolic characteristics of people's in-vivo tissue organ, by carrying out early diagnosis to a series of major diseases such as tumor, cardiovascular disease, nervous system disease to the analysis of these metabolic characteristicss, be the pith of medical image, there are bright prospects.
Aspect tumor disease diagnosis, in diagnosis, bring into play important function based on X ray or ultrasonic diagnostic techniques and method, significantly improve diagnosis and therapeutic effect.But these methods are the diagnostic imaging based on structure pathological changes all, in canceration type and by stages, the aspect effect such as qualitative is poor, during to soft-tissue imaging, picture quality is also difficult to meet early diagnosis requirement.MRI soft-tissue imaging can obtain good contrast effect, but imaging specificity is lower, easily cause fail to pinpoint a disease in diagnosis, mistaken diagnosis.Biomedical research shows, before recurring structure pathological changes, in its function, there is pathological changes in human organ, molecular image diagnostic device based on positron emission tomography can change and carry out imaging metabolic function, therefore can be more early stage tumor disease be diagnosed, further improves diagnosis and therapeutic effect.
At present for the PET(functional metabolism video picture of tumor disease diagnosis) imaging device mainly comprises polygonized structure and two slab constructions.Polygonized structure detection angle is more, do not need detector to carry out motor control, but application scenarios is more fixing, and underaction, cost is also relatively high.Two slab constructions can be controlled two distances between flat board, and can rotating acquisition different angles, and imaging mode is flexible and changeable, and application scenarios is also more extensive.But relatively large in detector area, when distance is relatively near, therefore have obvious effect of depth (DOI), effect of depth makes the line of response (LOR) that meets recording depart from positron-electron annihilation position, finally causes reconstructed image quality to decline.
The texture form that is used for the scintillator detector of PET imaging device comprises crystal strip array and continuous crystal.Crystal strip array can obtain the plan-position of incident γ photon eaily, and reading circuit is relative with location algorithm simple, but cannot provide the depth information of incident γ photon, and spatial resolution is also limited to the size of crystal bar, exists and surveys dead band.
Summary of the invention
For problems of the prior art, object of the present invention is for providing a kind of high-resolution imaging device.
For achieving the above object, technical scheme of the present invention is as follows:
A kind of two flat panel imaging devices based on continuous crystal, comprise two detecting modules, described detecting module comprises continuous crystal, photoelectric conversion part and array read-out electronics system, described photoelectric conversion part is adjacent to described continuous crystal, and described array read-out electronics system is connected with described photoelectric conversion part.
Further, four sides of described continuous crystal and upper surface scribble light absorbent.
Further, described continuous crystal is connected by photoconduction or optic grease direct-coupling with described photoelectric conversion part.
Further, described array read-out electronics system is that multichannel is read.
Further, also comprise and meet plate and host computer data handling system, described two detecting modules are all connected to described host computer data handling system by the described plate that meets, the described plate that meets judges described in two, whether two γ photon signals of detecting module collection take place at the same instant, and two signals is sent in this way to described host computer data handling system.
Further, described host computer data handling system or described array read-out electronics system comprise matching unit, position, described photoelectric conversion part comprises multiple probe units of array arrangement, matching unit, described position is according to the detected intensity distribution I (m of described each probe unit, n), matching draws γ photon that extraneous radioactive source is injected and active position s (x, the y of described continuous crystal, z) Position Number that, wherein m and n are probe unit.
Further, matching unit, described position adopts solid angle model, and in described photoelectric conversion part, (m, n) individual probe unit is to point source position s(x, y, z) open solid angle and be specially:
Wherein,
be that (m, n) individual probe unit is to point source position s(x, y, z) open solid angle;
W is the width of each probe unit;
H is the height of each probe unit;
X, y, z is the active position of described γ photon and continuous crystal.
Further, adopt solid angle model to carry out matching to γ photon and the active position of continuous crystal, and in model of fit, introduce normalization factor A, and
Compared with prior art, the present invention adopts two slab constructions, and detecting module of the present invention adopts continuous crystal in the present invention, effectively solve effect of depth, and do not exist and survey dead band, be conducive to improve detection efficient and detectivity, thereby improve precision and the reliability of imaging.
Accompanying drawing explanation
Below in conjunction with accompanying drawing, the present invention is described in further detail:
Fig. 1 is the structural representation of imaging device of the present invention;
Fig. 2 is the photoconduction connection diagram of the first embodiment in imaging device of the present invention;
Fig. 3 is the optic grease coupling schematic diagram of the second embodiment in imaging device of the present invention;
Fig. 4 is that in imaging device of the present invention, probe unit responds schematic diagram to point source.
The specific embodiment
The exemplary embodiments that embodies feature & benefits of the present invention will describe in detail in the following description.Be understood that the present invention can have various variations on different embodiment, it neither departs from the scope of the present invention, and explanation wherein and accompanying drawing be when the use that explain in itself, but not in order to limit the present invention.
As depicted in figs. 1 and 2, imaging device of the present invention comprises that 1, two detecting module 1 of two detecting modules all meets plate 2 by one and is connected to host computer data handling system 3.Detecting module 1 is fixed in a machinery (not shown) adjustably, comprises the continuous crystal 11, photoelectric conversion part 12 and the array read-out electronics system 13 that are connected successively.
11 4 sides of crystal and upper surface scribble light absorbent continuously, and lower surface is adopted to polishing, and crystal 11 is passage of scintillation light by the γ photon conversion of 511keV continuously.Crystal type can be selected LYSO, can be also BGO, LSO, LuAP, LFS, GSO, GYSO, NaI(Tl), CsI(Tl) and LaBr3 etc.; Crystal shape can be selected cuboid, can be also the geometries such as terrace with edge; Plane of crystal processing mode also can adopt polishing, extinction processing, and diffuse-reflectance processing etc., the model of fit that different surface treatment modes is selected is also different.
The passage of scintillation light that photoelectric conversion part 12 produces continuous crystal is converted to the signal of telecommunication, obtains the Two dimensional Distribution situation of passage of scintillation light intensity at continuous crystal lower surface.Photoelectric conversion part 12 can be square photomultiplier tube, standard circular photomultiplier tube, and multichannel photoelectricity multiplier tube, location-sensitive photomultiplier tube, based on the photomultiplier tube of microchannel plate, avalanche photodide array etc.
Between crystal 11, photoelectric conversion part 12, adopting optical transmission medium 14 to connect continuously.This optical transmission medium 14 can be that photoconduction 141 as shown in Figure 2 connects, and also can be coupled by optic grease 142 as shown in Figure 3.Photoconduction 141 is optional with fiber optic materials, specifically can be selected from glass, quartz, polystyrene, acrylic acid, polyethylene toluene or remain on liquid core photoconduction in minor diameter teflon pipe etc.
Array read-out electronics system 13 comprises that signal amplifies molding, digitized and network transmission module, and the signal of telecommunication that photoelectric conversion part 12 is sent amplifies molding and digitized, by network transmission module, data is dealt into and meets plate 2.
Meet the two γ photon signals that plate 2 judges that two detecting modules 1 send and whether take place at the same instant, two signals are sent to host computer data handling system 3 in this way and resolve; Be that two signals are not from same example as denied, thereby give up.
Host computer data handling system 3 or array read-out electronics system 13 comprise matching unit, position, according to the detected intensity distribution I (m of each probe unit in photoelectric conversion part, and solid angle distributed model n), matching draws the active position s (x of γ photon and continuous crystal, y, z).Fitting formula is:
Wherein, m, n are independent variable, and I is dependent variable, and x, y, z, A are the parameter of wanting matching.
W is the width of each probe unit;
H is the height of each probe unit;
X, y, z is the active position of γ photon and continuous crystal;
A is normalization factor.
In photoelectric conversion part 12 detected intensity of (m, n) individual probe unit for normalization factor and probe unit the product to point source solid angle that open position.
Technical scheme of the present invention is disclosed as above by preferred embodiment.Those skilled in the art should recognize change and the retouching the scope and spirit of the present invention that the appended claim of the present invention discloses, done in the case of not departing from, within all belonging to the protection domain of claim of the present invention.
Claims (8)
1. the two flat panel imaging devices based on continuous crystal, it is characterized in that, comprise two detecting modules, described detecting module comprises continuous crystal, photoelectric conversion part and array read-out electronics system, described photoelectric conversion part is adjacent to described continuous crystal, and described array read-out electronics system is connected with described photoelectric conversion part.
2. the two flat panel imaging devices based on continuous crystal as claimed in claim 1, is characterized in that, four sides of described continuous crystal and upper surface scribble light absorbent.
3. the two flat panel imaging devices based on continuous crystal as claimed in claim 1, is characterized in that, described continuous crystal is connected by photoconduction or optic grease direct-coupling with described photoelectric conversion part.
4. the two flat panel imaging devices based on continuous crystal as claimed in claim 1, is characterized in that, described array read-out electronics system is that multichannel is read.
5. the two flat panel imaging devices based on continuous crystal as described in as arbitrary in claim 1-4, it is characterized in that, also comprise and meet plate and host computer data handling system, described two detecting modules are all connected to described host computer data handling system by the described plate that meets, the described plate that meets judges described in two, whether two γ photon signals of detecting module collection take place at the same instant, and two signals is sent in this way to described host computer data handling system.
6. the two flat panel imaging devices based on continuous crystal as claimed in claim 5, it is characterized in that, described host computer data handling system or described array read-out electronics system comprise matching unit, position, described photoelectric conversion part comprises multiple probe units of array arrangement, matching unit, described position is according to the detected intensity distribution I (m of described each probe unit, n), matching draws γ photon that extraneous radioactive source is injected and the active position s (x of described continuous crystal, y, z) Position Number that, wherein m and n are probe unit.
7. the two flat panel imaging devices based on continuous crystal as claimed in claim 6, is characterized in that, matching unit, described position adopts solid angle model, (m in described photoelectric conversion part, n) individual probe unit is to point source position s(x, y, z) open solid angle and be specially:
Wherein,
be that (m, n) individual probe unit is to point source position s(x, y, z) open solid angle;
W is the width of each probe unit;
H is the height of each probe unit;
X, y, z is the active position of described γ photon and continuous crystal.
8. the two flat panel imaging devices based on continuous crystal as claimed in claim 7, is characterized in that, adopt solid angle model to carry out matching to γ photon and the active position of continuous crystal, and in model of fit, introduce normalization factor A, and
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| Application Number | Priority Date | Filing Date | Title |
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| CN201410056890.8A CN103800023B (en) | 2014-02-19 | 2014-02-19 | A kind of two flatbed imaging device based on continuous crystal |
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| CN201410056890.8A CN103800023B (en) | 2014-02-19 | 2014-02-19 | A kind of two flatbed imaging device based on continuous crystal |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106597518A (en) * | 2016-12-21 | 2017-04-26 | 中国科学院深圳先进技术研究院 | PET detector, PET imaging system and PET tester |
| CN109924995A (en) * | 2017-12-15 | 2019-06-25 | 深圳先进技术研究院 | Both-end reads detector cells and both-end reads detector |
| CN110477942A (en) * | 2019-08-20 | 2019-11-22 | 上海联影医疗科技有限公司 | A kind of pet detector and medical imaging device |
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| CN1203668A (en) * | 1995-10-12 | 1998-12-30 | 阿达克实验室 | Resolution enhancement for dual head gamma camera |
| US6175116B1 (en) * | 1997-06-02 | 2001-01-16 | Picker International, Inc. | Hybrid collimation and coincidence imager for simultaneous positron and single photon imaging |
| US20060027755A1 (en) * | 2002-07-05 | 2006-02-09 | Washington University | Method and apparatus for increasing spatial resolution of a pet scanner |
| CN102655813A (en) * | 2009-10-27 | 2012-09-05 | 华盛顿大学商业中心 | Optical-interface patterning for radiation detector crystals |
| CN103099637A (en) * | 2013-02-21 | 2013-05-15 | 清华大学 | Image reconstruction method for dual panel position-emission tomography (PET) detector |
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- 2014-02-19 CN CN201410056890.8A patent/CN103800023B/en not_active Expired - Fee Related
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1203668A (en) * | 1995-10-12 | 1998-12-30 | 阿达克实验室 | Resolution enhancement for dual head gamma camera |
| US6175116B1 (en) * | 1997-06-02 | 2001-01-16 | Picker International, Inc. | Hybrid collimation and coincidence imager for simultaneous positron and single photon imaging |
| US20060027755A1 (en) * | 2002-07-05 | 2006-02-09 | Washington University | Method and apparatus for increasing spatial resolution of a pet scanner |
| CN102655813A (en) * | 2009-10-27 | 2012-09-05 | 华盛顿大学商业中心 | Optical-interface patterning for radiation detector crystals |
| CN103099637A (en) * | 2013-02-21 | 2013-05-15 | 清华大学 | Image reconstruction method for dual panel position-emission tomography (PET) detector |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106597518A (en) * | 2016-12-21 | 2017-04-26 | 中国科学院深圳先进技术研究院 | PET detector, PET imaging system and PET tester |
| CN109924995A (en) * | 2017-12-15 | 2019-06-25 | 深圳先进技术研究院 | Both-end reads detector cells and both-end reads detector |
| CN110477942A (en) * | 2019-08-20 | 2019-11-22 | 上海联影医疗科技有限公司 | A kind of pet detector and medical imaging device |
| CN110477942B (en) * | 2019-08-20 | 2023-06-23 | 上海联影医疗科技股份有限公司 | PET detector and medical imaging equipment |
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