CA2633447A1 - Aerosol medication delivery apparatus and system - Google Patents

Aerosol medication delivery apparatus and system Download PDF

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Publication number
CA2633447A1
CA2633447A1 CA002633447A CA2633447A CA2633447A1 CA 2633447 A1 CA2633447 A1 CA 2633447A1 CA 002633447 A CA002633447 A CA 002633447A CA 2633447 A CA2633447 A CA 2633447A CA 2633447 A1 CA2633447 A1 CA 2633447A1
Authority
CA
Canada
Prior art keywords
delivery apparatus
medication
aerosol
medication delivery
output end
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002633447A
Other languages
French (fr)
Other versions
CA2633447C (en
Inventor
James Schmidt
Jerry Grychowski
Daniel K. Engelbreth
Robert Morton
Martin P. Foley
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Trudell Medical International
Original Assignee
Trudell Medical International
James Schmidt
Jerry Grychowski
Daniel K. Engelbreth
Robert Morton
Martin P. Foley
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Trudell Medical International, James Schmidt, Jerry Grychowski, Daniel K. Engelbreth, Robert Morton, Martin P. Foley filed Critical Trudell Medical International
Priority to CA2789111A priority Critical patent/CA2789111A1/en
Publication of CA2633447A1 publication Critical patent/CA2633447A1/en
Application granted granted Critical
Publication of CA2633447C publication Critical patent/CA2633447C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/06—Respiratory or anaesthetic masks
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/001—Particle size control
    • A61M11/002—Particle size control by flow deviation causing inertial separation of transported particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/001—Particle size control
    • A61M11/003—Particle size control by passing the aerosol trough sieves or filters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0001—Details of inhalators; Constructional features thereof
    • A61M15/0013—Details of inhalators; Constructional features thereof with inhalation check valves
    • A61M15/0016—Details of inhalators; Constructional features thereof with inhalation check valves located downstream of the dispenser, i.e. traversed by the product
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0086—Inhalation chambers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/06—Respiratory or anaesthetic masks
    • A61M16/0605—Means for improving the adaptation of the mask to the patient
    • A61M16/0616—Means for improving the adaptation of the mask to the patient with face sealing means comprising a flap or membrane projecting inwards, such that sealing increases with increasing inhalation gas pressure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/009—Inhalators using medicine packages with incorporated spraying means, e.g. aerosol cans

Abstract

An aerosol medication delivery apparatus (910) for use with a pMDI canister having medication and a propellant contained therein under pressure, wherein the pMDI canister has a discharge orifice from which the medication and propellant can be discharged forming an aerosol, the apparatus comprising: a chamber (924) housing having an input end (946) and an output end (948) and defining an interior space (939), wherein the input end receives the medication discharged from the discharge orifice of the pMDI canister into the interior space and wherein the medication can be withdrawn from the interior space by inhalation by a patient from the output end; a mouthpiece (955) operatively attached to the output end; and a valve (960) located near the output end comprising a valve seat (964) having a sealing surface (966) and a valve member (962) comprising an inner portion (963) and an outer portion (965), the inner portion having a central open area (961) and a sealing portion at the perimeter of the central open area that mates with the sealing surface when the valve is closed, wherein the inner portion allows medication to be withdrawn through the central open area but prevents backflow into the chamber housing and the outer portion located in a peripheral opening defined between the chamber housing and the mouthpiece, the outer portion operative to prevent air flow through the peripheral opening upon patient inhalation but which permits air flow through the peripheral opening upon exhalation into the mouthpiece.

Claims (38)

1. An aerosol medication delivery apparatus for use with a pMDI
canister having medication and a propellant contained therein under pressure, wherein the pMDI canister has a discharge orifice from which the medication and propellant can be discharged forming an aerosol, the apparatus comprising a chamber housing having an input end and an output end and defining an interior space, wherein the input end receives the medication discharged from the discharge orifice of the pMDI canister into the interior space and wherein the medication can be withdrawn from the interior space by inhalation by a patient from the output end, and a valve at the output end comprising a valve seat and a valve member, the valve seat having a sealing surface and the valve member having a central open area and a sealing portion at the perimeter of the central open area that mates with the sealing surface when the valve is closed, wherein the valve allows medication to be withdrawn through the central open area but prevents backflow into the chamber housing.
2. The aerosol medication delivery apparatus of Claim 1, further comprising a containment baffle located at the output end.
3. The aerosol medication delivery apparatus of Claim 2, wherein the sealing surface is formed on the outer perimeter of the containment baffle.
4. The aerosol medication delivery apparatus of Claim 2, wherein the containment baffle is dome shaped and includes a concave surface and a convex surface.
5. The aerosol medication delivery apparatus of Claim 4, wherein the convex surface faces downstream and the concave surface faces toward the input end of the chamber.
6. The aerosol medication delivery apparatus of Claim 1, further comprising a retainer defining a channel, the retainer located near the output end.
7. The aerosol medication delivery apparatus of Claim 6, further comprising an engaging member located on the valve member, wherein the engaging member is movable between a first position and a second position within the channel.
8. The aerosol medication delivery apparatus of Claim 4, wherein the convex surface faces toward the input end of the chamber housing.
9. The aerosol medication delivery apparatus of Claim 1, wherein the central open area.is circular shaped.
10. The aerosol medication delivery apparatus of Claim 2, wherein the valve member has an inner portion, an outer portion and an engaging member.
11. The aerosol medication delivery apparatus of Claim 10, wherein inhalation openings are located near the output end and are defined between the containment baffle and the chamber housing.
12. The aerosol medication delivery apparatus of Claim 11, further comprising a protrusion formed near the output end on the outer surface of the chamber housing.
13. The aerosol medication delivery apparatus of Claim 11 wherein the inner portion is positioned adjacent the inhalation openings.
14. The aerosol medication delivery apparatus of Claim 12, wherein the engagement member concentrically surrounds the protrusion.
15. The aerosol medication delivery apparatus of Claim 1, wherein the valve member is dome shaped in cross section.
16. The aerosol medication delivery apparatus of Claim 1, further comprising a downstream portion attached with the output end.
17. The aerosol medication delivery apparatus of Claim 16, wherein the downstream portion has an inner surface and a plurality of retaining ribs spaced apart from the inner surface.
18. The aerosol medication delivery apparatus of Claim 17, wherein the retaining ribs define gaps which permit exhaled air to flow through to the atmosphere.
19. The aerosol medication delivery apparatus of Claim 1, wherein the valve member is made of a rigid material.
20. The aerosol medication delivery apparatus of Claim 1, wherein the sealing portion forms a continuous surface.
21. An aerosol medication delivery apparatus for use with a pMDI
canister having medication and a propellant contained therein under pressure, wherein the pMDI canister has a discharge orifice from which the medication and propellant can be discharged forming an aerosol, the apparatus comprising:
a chamber housing having an input end and an output end and defining an interior space, wherein the input end receives the medication discharged from the discharge orifice of the pMDI canister into the interior space and wherein the medication can be withdrawn from the interior space by inhalation by a patient from the output end;
a mouthpiece operatively attached to the output end; and a valve located near the output end comprising a valve seat having a sealing surface and a valve member comprising an inner portion and an outer portion, the inner portion having a central open area and a sealing portion at the perimeter of the central open area that mates with the sealing surface when the valve is closed, wherein the inner portion allows medication to be withdrawn through the central open area but prevents backflow into the chamber housing and the outer portion located in a peripheral opening defined between the chamber housing and the mouthpiece, the outer portion operative to prevent air flow through the peripheral opening upon patient inhalation but which permits air flow through the peripheral opening upon exhalation into the mouthpiece.
22. The aerosol medication delivery apparatus of Claim 21, wherein a containment baffle is located at the output end to partially block the output end.
23. The aerosol medication delivery apparatus of Claim 22, wherein the sealing surface is located at the periphery of the containment baffle.
24. An aerosol medication delivery apparatus for use with a pMDI
canister having medication and a propellant contained therein under pressure, wherein the pMDI canister has a discharge orifice from which the medication and propellant can be discharged forming an aerosol, the apparatus comprising:
a chamber housing having an input end and an output end and defining an interior space, wherein the input end receives the medication discharged from the discharge orifice of the pMDI canister into the interior space and wherein the medication can be withdrawn from the interior space by inhalation by a patient from the output end; and a valve at the output end comprising a valve seat and a valve member, the valve seat having a sealing surface and the valve member having a central open area and a sealing portion at the perimeter of the central open area that mates with the sealing surface when the valve is closed; and an engagement member located on the valve member, wherein the valve allows medication to be withdrawn through the central open area but prevents backflow into the chamber housing.
25. The aerosol medication delivery apparatus of Claim 24, wherein the valve member has an inner portion.
26. The aerosol medication delivery apparatus of Claim 24, wherein the engagement member includes an input side and an output side.
27. The aerosol medication delivery apparatus of Claim 26, further comprising a downstream portion attached to the output end.
28. The aerosol medication delivery apparatus of Claim 27, wherein an inner surface of the downstream portion defines a recess.
29. The aerosol medication delivery apparatus of Claim 28, wherein the output side of the engagement member is disposed in the recess.
30. The aerosol medication delivery apparatus of Claim 24, wherein the central open area is circular shaped.
31. The aerosol medication delivery apparatus of Claim 24 wherein the diameter of the chamber housing gradually increases from the input end to the output end.
32. The aerosol medication delivery apparatus of Claim 26, wherein a baffle member is attached to the output end.
33. The aerosol medication delivery apparatus of Claim 32 wherein a receiving member is formed on a downstream end of the baffle member.
34. The aerosol medication delivery apparatus of Claim 33, wherein the input side of the engaging member is concentrically disposed around the receiving member.
35. The aerosol medication delivery apparatus of Claim 24, wherein a mask is attached to the output end.
36. The aerosol medication delivery apparatus of Claim 24, wherein the sealing portion forms a continuous surface.
37. A method for delivering aerosol medication to a patient, comprising the steps of:

providing a pMDI canister having medication and a propellant contained therein under pressure, wherein the pMDI canister has a discharge orifice;
providing a chamber housing having an input end and an output end and defining an interior space, wherein said input end receives the medication discharged from the orifice of the pMDI canister into said interior space and wherein the medication can be withdrawn from said interior space by inhalation by a patient from the output end; and providing a valve at the output end comprising a valve seat and a valve member, the valve seat having a sealing surface and the valve member having a central open area and a sealing portion at the perimeter of the central open area;
depressing the pMDI canister discharging medication and propellant out from the discharge orifice;
forming an aerosolized medication; and passing aerosolized medication through the chamber and to the patient.
38. An aerosol medication delivery apparatus for use with a pMDI
canister having medication and a propellant contained therein under pressure, wherein the pMDI canister has a discharge orifice from which the medication and propellant can be discharged forming an aerosol, the apparatus comprising:
a chamber housing having an input end and an output end and defining an interior space, wherein the input end receives the medication discharged from the discharge orifice of the pMDI canister into the interior space and wherein the medication can be withdrawn from the interior space by inhalation by a patient from the output end;
means for sealing the chamber housing comprising a base and a movable member movable between an open position and a closed position, the movable member having a central open area, wherein the means for sealing the chamber housing allows medication to be withdrawn through said central open area when the movable member is in the open position but prevents backflow into said chamber housing when the movable member is in the closed position.
CA2633447A 1999-04-07 2000-04-07 Aerosol medication delivery apparatus and system Expired - Lifetime CA2633447C (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA2789111A CA2789111A1 (en) 1999-04-07 2000-04-07 Aerosol medication delivery apparatus and system

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/287,997 1999-04-07
US09/287,997 US6293279B1 (en) 1997-09-26 1999-04-07 Aerosol medication delivery apparatus and system
CA002369865A CA2369865C (en) 1999-04-07 2000-04-07 Aerosol medication delivery apparatus and system

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CA002369865A Division CA2369865C (en) 1999-04-07 2000-04-07 Aerosol medication delivery apparatus and system

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CA2789111A Division CA2789111A1 (en) 1999-04-07 2000-04-07 Aerosol medication delivery apparatus and system

Publications (2)

Publication Number Publication Date
CA2633447A1 true CA2633447A1 (en) 2000-10-12
CA2633447C CA2633447C (en) 2012-10-30

Family

ID=23105313

Family Applications (3)

Application Number Title Priority Date Filing Date
CA002369865A Expired - Lifetime CA2369865C (en) 1999-04-07 2000-04-07 Aerosol medication delivery apparatus and system
CA2789111A Abandoned CA2789111A1 (en) 1999-04-07 2000-04-07 Aerosol medication delivery apparatus and system
CA2633447A Expired - Lifetime CA2633447C (en) 1999-04-07 2000-04-07 Aerosol medication delivery apparatus and system

Family Applications Before (2)

Application Number Title Priority Date Filing Date
CA002369865A Expired - Lifetime CA2369865C (en) 1999-04-07 2000-04-07 Aerosol medication delivery apparatus and system
CA2789111A Abandoned CA2789111A1 (en) 1999-04-07 2000-04-07 Aerosol medication delivery apparatus and system

Country Status (10)

Country Link
US (2) US6293279B1 (en)
EP (3) EP2343096B1 (en)
JP (2) JP4578689B2 (en)
AT (1) ATE340599T1 (en)
AU (1) AU773283B2 (en)
CA (3) CA2369865C (en)
DE (1) DE60030964T2 (en)
ES (3) ES2688386T3 (en)
MX (1) MXPA01010153A (en)
WO (1) WO2000059565A1 (en)

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