CA2604498A1 - Variable volume, shape memory actuated insulin dispensing pump - Google Patents
Variable volume, shape memory actuated insulin dispensing pump Download PDFInfo
- Publication number
- CA2604498A1 CA2604498A1 CA002604498A CA2604498A CA2604498A1 CA 2604498 A1 CA2604498 A1 CA 2604498A1 CA 002604498 A CA002604498 A CA 002604498A CA 2604498 A CA2604498 A CA 2604498A CA 2604498 A1 CA2604498 A1 CA 2604498A1
- Authority
- CA
- Canada
- Prior art keywords
- piston
- shape memory
- pump
- chamber
- liquid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
- F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
- F04B35/00—Piston pumps specially adapted for elastic fluids and characterised by the driving means to their working members, or by combination with, or adaptation to, specific driving engines or motors, not otherwise provided for
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/14212—Pumping with an aspiration and an expulsion action
- A61M5/14216—Reciprocating piston type
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F03—MACHINES OR ENGINES FOR LIQUIDS; WIND, SPRING, OR WEIGHT MOTORS; PRODUCING MECHANICAL POWER OR A REACTIVE PROPULSIVE THRUST, NOT OTHERWISE PROVIDED FOR
- F03G—SPRING, WEIGHT, INERTIA OR LIKE MOTORS; MECHANICAL-POWER PRODUCING DEVICES OR MECHANISMS, NOT OTHERWISE PROVIDED FOR OR USING ENERGY SOURCES NOT OTHERWISE PROVIDED FOR
- F03G7/00—Mechanical-power-producing mechanisms, not otherwise provided for or using energy sources not otherwise provided for
- F03G7/06—Mechanical-power-producing mechanisms, not otherwise provided for or using energy sources not otherwise provided for using expansion or contraction of bodies due to heating, cooling, moistening, drying or the like
- F03G7/065—Mechanical-power-producing mechanisms, not otherwise provided for or using energy sources not otherwise provided for using expansion or contraction of bodies due to heating, cooling, moistening, drying or the like using a shape memory element
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
- F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
- F04B17/00—Pumps characterised by combination with, or adaptation to, specific driving engines or motors
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
- F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
- F04B23/00—Pumping installations or systems
- F04B23/02—Pumping installations or systems having reservoirs
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
- F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
- F04B35/00—Piston pumps specially adapted for elastic fluids and characterised by the driving means to their working members, or by combination with, or adaptation to, specific driving engines or motors, not otherwise provided for
- F04B35/04—Piston pumps specially adapted for elastic fluids and characterised by the driving means to their working members, or by combination with, or adaptation to, specific driving engines or motors, not otherwise provided for the means being electric
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
- F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
- F04B49/00—Control, e.g. of pump delivery, or pump pressure of, or safety measures for, machines, pumps, or pumping installations, not otherwise provided for, or of interest apart from, groups F04B1/00 - F04B47/00
- F04B49/06—Control using electricity
- F04B49/065—Control using electricity and making use of computers
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
- F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
- F04B9/00—Piston machines or pumps characterised by the driving or driven means to or from their working members
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
- F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
- F04B9/00—Piston machines or pumps characterised by the driving or driven means to or from their working members
- F04B9/02—Piston machines or pumps characterised by the driving or driven means to or from their working members the means being mechanical
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01F—MEASURING VOLUME, VOLUME FLOW, MASS FLOW OR LIQUID LEVEL; METERING BY VOLUME
- G01F11/00—Apparatus requiring external operation adapted at each repeated and identical operation to measure and separate a predetermined volume of fluid or fluent solid material from a supply or container, without regard to weight, and to deliver it
- G01F11/02—Apparatus requiring external operation adapted at each repeated and identical operation to measure and separate a predetermined volume of fluid or fluent solid material from a supply or container, without regard to weight, and to deliver it with measuring chambers which expand or contract during measurement
- G01F11/021—Apparatus requiring external operation adapted at each repeated and identical operation to measure and separate a predetermined volume of fluid or fluent solid material from a supply or container, without regard to weight, and to deliver it with measuring chambers which expand or contract during measurement of the piston type
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/02—General characteristics of the apparatus characterised by a particular materials
- A61M2205/0266—Shape memory materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/02—General characteristics of the apparatus characterised by a particular materials
- A61M2205/0272—Electro-active or magneto-active materials
- A61M2205/0288—Electro-rheological or magneto-rheological materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/33—Controlling, regulating or measuring
- A61M2205/3317—Electromagnetic, inductive or dielectric measuring means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/70—General characteristics of the apparatus with testing or calibration facilities
- A61M2205/702—General characteristics of the apparatus with testing or calibration facilities automatically during use
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
- F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
- F04B2201/00—Pump parameters
- F04B2201/02—Piston parameters
- F04B2201/0201—Position of the piston
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F05—INDEXING SCHEMES RELATING TO ENGINES OR PUMPS IN VARIOUS SUBCLASSES OF CLASSES F01-F04
- F05C—INDEXING SCHEME RELATING TO MATERIALS, MATERIAL PROPERTIES OR MATERIAL CHARACTERISTICS FOR MACHINES, ENGINES OR PUMPS OTHER THAN NON-POSITIVE-DISPLACEMENT MACHINES OR ENGINES
- F05C2251/00—Material properties
- F05C2251/08—Shape memory
Abstract
A portable pumping system provides insulin or other drugs to a user. A shape memory element is used to actuate the pump and an intelligent system controls the actuator in order to minimize stresses within the system and provide accurate and reliable dosage delivery. The control system utilizes various types of feedback to monitor and optimize the position of the pumping mechanisms. Physical design aspects also minimize stress and the combination of the physical design aspects and the intelligent operation of the system results in a lightweight and cost effective pump that may be used in a disposable fashion if desired.
Claims (27)
1. A pumping system comprising:
a chamber;
a piston within the chamber;
a shape memory element within the chamber that changes length when a current flows through the element, the element moving the piston between a first and second physical limit, such that when the piston is at the first limit the chamber is occupied with liquid and when the chamber is at the second limit the chamber is substantially discharged of liquid; and a first switch at the first limit that indicates if the piston is at the first limit.
a chamber;
a piston within the chamber;
a shape memory element within the chamber that changes length when a current flows through the element, the element moving the piston between a first and second physical limit, such that when the piston is at the first limit the chamber is occupied with liquid and when the chamber is at the second limit the chamber is substantially discharged of liquid; and a first switch at the first limit that indicates if the piston is at the first limit.
2. The pumping system of claim 1 further comprising a second switch at the second limit that indicates if the piston is at the second limit.
3. The pumping system of claim 2 further comprising circuitry that senses the condition of the first and second switches.
4. The pumping system of claim 3 wherein the circuitry is operable to detect a pump malfunction if the piston is not at the first or second limit.
5. A method of dispensing a liquid, comprising:
drawing liquid into a pumping chamber by causing a shape memory material to contract and move a piston;
expelling liquid from the pumping chamber by causing the shape memory material to relax and move the piston;
monitoring the position of the piston; and controlling the position of the piston based upon the monitored position.
drawing liquid into a pumping chamber by causing a shape memory material to contract and move a piston;
expelling liquid from the pumping chamber by causing the shape memory material to relax and move the piston;
monitoring the position of the piston; and controlling the position of the piston based upon the monitored position.
6. The method of claim 5 wherein monitoring the position of the piston comprises sensing the condition of one or more switches selectively activated depending upon the position of the piston.
7. The method of claim 5 wherein monitoring the position of the piston comprises utilizing encoding indicia provided on the piston.
8. The method of claim 5 wherein monitoring the position of the piston comprises measuring the strength of a magnetic field.
9. The method of claim 5 wherein monitoring the position of the piston comprises measuring the capacitance between a stationary conductive element and a conductive element that moves with the piston.
10. A hydraulic pump comprising:
a chamber;
a piston within the chamber;
a shape memory element that drives the piston;
a stroke length equal to the maximum distance of travel of a pumping surface of the piston;
a position sensing mechanism that senses the position of the piston; and a positioning system including a linear feedback mechanism, wherein the positioning system moves the piston in increments less than the stroke length, resulting in a partial piston stroke.
a chamber;
a piston within the chamber;
a shape memory element that drives the piston;
a stroke length equal to the maximum distance of travel of a pumping surface of the piston;
a position sensing mechanism that senses the position of the piston; and a positioning system including a linear feedback mechanism, wherein the positioning system moves the piston in increments less than the stroke length, resulting in a partial piston stroke.
11. The pump of claim 10 wherein the position sensing mechanism utilizes optical encoding.
12. The pump of claim 10 wherein the position sensing mechanism utilizes conductive encoding.
13. The pump of claim 10 wherein the position sensing mechanism comprises a magnetic sensor.
14. The pump of claim 10 wherein the position sensing mechanism measures the capacitance between a stationary conductive element and a conductive element that moves with the piston.
15. A pump comprising:
a reservoir having a maximum volume;
an actuator comprising a shape memory alloy that moves a plunger, the plunger displacing liquid from the reservoir; and a control system that utilizes linear feedback to sense the position of the actuator and to manipulate the actuator to provide doses of variable volumes less than the maximum volume.
a reservoir having a maximum volume;
an actuator comprising a shape memory alloy that moves a plunger, the plunger displacing liquid from the reservoir; and a control system that utilizes linear feedback to sense the position of the actuator and to manipulate the actuator to provide doses of variable volumes less than the maximum volume.
16. The pump of claim 15 wherein the control system comprises a microprocessor.
17. The pump of claim 15 wherein the control system comprises means for position detection.
18. The pump of claim 15 wherein the control system determines if the pump is primed or not.
19. The pump of claim 18 wherein if the pump is not primed the control system creates a warning.
20. A pump comprising:
a shape memory alloy;
a piston connected to the shape memory alloy, said piston having a stroke length;
means for sensing the precise position of the piston at any point of the piston stroke; and means for controlling the position of the piston by changing the length of the shape memory alloy, said means for controlling able to position the piston at any point of the piston stroke thereby enabling the pump to pump variable dosage sizes of a liquid.
a shape memory alloy;
a piston connected to the shape memory alloy, said piston having a stroke length;
means for sensing the precise position of the piston at any point of the piston stroke; and means for controlling the position of the piston by changing the length of the shape memory alloy, said means for controlling able to position the piston at any point of the piston stroke thereby enabling the pump to pump variable dosage sizes of a liquid.
21. A method of dispensing a liquid, comprising:
providing a piston connected to a shape memory element;
providing a potential to the shape memory element in order to change the length of the element, monitoring the position of the piston; and adjusting the potential applied to the shape memory element to move the piston and dispense liquid, based upon the monitored position.
providing a piston connected to a shape memory element;
providing a potential to the shape memory element in order to change the length of the element, monitoring the position of the piston; and adjusting the potential applied to the shape memory element to move the piston and dispense liquid, based upon the monitored position.
22. The method of claim 21 wherein providing a potential comprises applying pulses of potential and adjusting the _potential comprises modulating the width of the applied pulses.
23. The method of claim 21 wherein monitoring the position comprises reading discrete position indicators.
24. The method of claim 22 wherein monitoring the position comprises measuring the variable output of an analog sensor.
25. A method of pumping a liquid, comprising:
applying at least one electrical pulse to a shape memory alloy to move a piston;
detecting a stressed state of the shape memory alloy; and modifying the at least one pulse if the stressed state is detected.
applying at least one electrical pulse to a shape memory alloy to move a piston;
detecting a stressed state of the shape memory alloy; and modifying the at least one pulse if the stressed state is detected.
26. The method of claim 25 further comprising:
checking for an occlusion; and modifying the at least one pulse if an occlusion is detected.
checking for an occlusion; and modifying the at least one pulse if an occlusion is detected.
27. A pumping system comprising:
a chamber;
a first piston within the chamber;
a shape memory element within the chamber that changes length when a current flows through the element, the element moving the first piston between a first and second physical limit, such that when the first piston is at the first limit the chamber is occupied with liquid and when the chamber is at the second limit the chamber is substantially discharged of liquid; and a second piston coupled to the shape memory element that moves to accommodate changes in the shape memory element and reduce stress on the pumping system.
a chamber;
a first piston within the chamber;
a shape memory element within the chamber that changes length when a current flows through the element, the element moving the first piston between a first and second physical limit, such that when the first piston is at the first limit the chamber is occupied with liquid and when the chamber is at the second limit the chamber is substantially discharged of liquid; and a second piston coupled to the shape memory element that moves to accommodate changes in the shape memory element and reduce stress on the pumping system.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CA2718306A CA2718306C (en) | 2005-04-13 | 2006-04-13 | Variable volume, shape memory actuated insulin dispensing pump |
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US11/106,155 | 2005-04-13 | ||
US11/106,155 US7993108B2 (en) | 2002-10-09 | 2005-04-13 | Variable volume, shape memory actuated insulin dispensing pump |
PCT/US2006/014228 WO2006113521A2 (en) | 2005-04-13 | 2006-04-13 | Variable volume, shape memory actuated insulin dispensing pump |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA2718306A Division CA2718306C (en) | 2005-04-13 | 2006-04-13 | Variable volume, shape memory actuated insulin dispensing pump |
Publications (2)
Publication Number | Publication Date |
---|---|
CA2604498A1 true CA2604498A1 (en) | 2006-10-26 |
CA2604498C CA2604498C (en) | 2010-10-19 |
Family
ID=37115768
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA2604498A Active CA2604498C (en) | 2005-04-13 | 2006-04-13 | Variable volume, shape memory actuated insulin dispensing pump |
CA2718306A Active CA2718306C (en) | 2005-04-13 | 2006-04-13 | Variable volume, shape memory actuated insulin dispensing pump |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA2718306A Active CA2718306C (en) | 2005-04-13 | 2006-04-13 | Variable volume, shape memory actuated insulin dispensing pump |
Country Status (5)
Country | Link |
---|---|
US (7) | US7993108B2 (en) |
EP (1) | EP1877662A4 (en) |
CN (1) | CN101189431B (en) |
CA (2) | CA2604498C (en) |
WO (1) | WO2006113521A2 (en) |
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WO2017189970A1 (en) * | 2016-04-29 | 2017-11-02 | Verily Life Sciences Llc | Air shot detection |
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US10953155B2 (en) | 2016-04-29 | 2021-03-23 | Verily Life Sciences Llc | Pressure sensor in plunger head to wake up electronics |
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CA2604498C (en) | 2010-10-19 |
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US20090163869A1 (en) | 2009-06-25 |
US20050238503A1 (en) | 2005-10-27 |
US8047812B2 (en) | 2011-11-01 |
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