CA2594417A1 - Novel electrode design for biosensor - Google Patents

Novel electrode design for biosensor Download PDF

Info

Publication number
CA2594417A1
CA2594417A1 CA002594417A CA2594417A CA2594417A1 CA 2594417 A1 CA2594417 A1 CA 2594417A1 CA 002594417 A CA002594417 A CA 002594417A CA 2594417 A CA2594417 A CA 2594417A CA 2594417 A1 CA2594417 A1 CA 2594417A1
Authority
CA
Canada
Prior art keywords
test strip
point
electrode
distance
conductive trace
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002594417A
Other languages
French (fr)
Other versions
CA2594417C (en
Inventor
Randall K. Riggles
Abner D. Joseph
Tom Funke
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F. Hoffmann-La Roche Ag
Randall K. Riggles
Abner D. Joseph
Tom Funke
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F. Hoffmann-La Roche Ag, Randall K. Riggles, Abner D. Joseph, Tom Funke filed Critical F. Hoffmann-La Roche Ag
Publication of CA2594417A1 publication Critical patent/CA2594417A1/en
Application granted granted Critical
Publication of CA2594417C publication Critical patent/CA2594417C/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28—Electrolytic cell components
    • G01N27/30—Electrodes, e.g. test electrodes; Half-cells
    • G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
    • G01N27/3271—Amperometric enzyme electrodes for analytes in body fluids, e.g. glucose in blood
    • G01N27/3272—Test elements therefor, i.e. disposable laminated substrates with electrodes, reagent and channels

Abstract

A test strip for measuring a signal of interest in a biological fluid when the test strip is mated to an appropriate test meter, wherein the test strip and the test meter include structures to verify the integrity of the test strip traces, to measure the parasitic resistance of the test strip traces, and to provide compensation in the voltage applied to the test strip to account for parasitic resistive losses in the test strip traces. In addition, conductive traces are positioned to ensure structural interrogation of all electrodes and traces present upon the test strip.

Claims (10)

1. An electrochemical test strip powered by a power source comprising:
a first measurement electrode (814a), and a first conductive trace (826) operatively coupled to the first measurement electrode, wherein the distance between at least one point on the first conductive trace and a contact zone (22) for contacting the power source is greater than or equal to the distance between any point on said first measurement electrode and the contact zone (22) for contacting the power source.
2. The test strip of claim 1, further comprising:
a second measurement electrode (216a), and a second conductive trace (224) operatively coupled to the second measurement electrode; wherein the distance between at least one point on the second conductive trace and the contact zone (22) for contacting the power source is greater than or equal to the distance between any point on said second measurement electrode and the contact zone (22) for contacting the power source.
3. The test strip of claim 1 wherein said first measurement electrode comprises a plurality of first fingers.
4. The test strip of claim 2 wherein said second measurement electrode comprises a plurality of second fingers.
5. The test strip of claim 2, further comprising a reagent disposed on said first fingers and operative to create an electrical potential in a fluid sample that is indicative of a desired fluid quality to be measured by the test strip.
6. The test strip of claim 3, further comprising a reagent disposed on said second fingers and operative to create an electrical potential in a fluid sample that is indicative of a desired fluid quality to be measured by the test strip.
7. The test strip of claim 1, wherein the at least one point on the first conductive trace is a point (1206) where the first conductive trace intersects the first measurement electrode.
8. The test strip of claim 2, wherein the at least one point on the second conductive trace is a point (1208) where the second conductive trace intersects the second measurement electrode.
9. An electrochemical test strip powered by a power source comprising a working electrode (814a); and a working sense line (826) operatively coupled to the working electrode, said working sense line intersects the working electrode in a point (1206), wherein the distance between said point (1206) and a contact zone (22) for contacting the power source on the test strip is greater than or equal to the distance between any point on the portion of the working electrode and the contact zone (22).
10. The test strip of claim 8, further comprising:
a counter electrode (216a); and a counter sense line (224) operatively coupled to the counter electrode;
Said counter sense line intersects the counter electrode in a point (1208), wherein the distance between said point (1208) and a contact zone(22) on the test strip is greater than or equal to the distance between any point on the portion of the counter electrode and the contact zone.
CA2594417A 2005-01-12 2006-01-12 Novel electrode design for biosensor Active CA2594417C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US11/033,704 2005-01-12
US11/033,704 US7556723B2 (en) 2004-06-18 2005-01-12 Electrode design for biosensor
PCT/EP2006/000222 WO2006074927A1 (en) 2005-01-12 2006-01-12 Novel electrode design for biosensor

Publications (2)

Publication Number Publication Date
CA2594417A1 true CA2594417A1 (en) 2006-07-20
CA2594417C CA2594417C (en) 2011-04-12

Family

ID=36013249

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2594417A Active CA2594417C (en) 2005-01-12 2006-01-12 Novel electrode design for biosensor

Country Status (9)

Country Link
US (1) US7556723B2 (en)
EP (1) EP1846761B1 (en)
JP (1) JP4827855B2 (en)
CN (1) CN101103271B (en)
CA (1) CA2594417C (en)
ES (1) ES2644041T3 (en)
HK (1) HK1115440A1 (en)
PL (1) PL1846761T3 (en)
WO (1) WO2006074927A1 (en)

Families Citing this family (49)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5993161A (en) * 1982-11-16 1984-05-29 松下冷機株式会社 Refrigerator
US7920906B2 (en) 2005-03-10 2011-04-05 Dexcom, Inc. System and methods for processing analyte sensor data for sensor calibration
EP1756557B1 (en) * 2004-05-21 2017-03-15 Agamatrix, Inc. Method of making an electrochemical cell
US7654956B2 (en) 2004-07-13 2010-02-02 Dexcom, Inc. Transcutaneous analyte sensor
US7517439B2 (en) * 2005-04-15 2009-04-14 Agamatrix, Inc. Error detection in analyte measurements based on measurement of system resistance
JP4944802B2 (en) * 2006-01-31 2012-06-06 パナソニック株式会社 Blood sensor and blood test apparatus having the same
US8529751B2 (en) 2006-03-31 2013-09-10 Lifescan, Inc. Systems and methods for discriminating control solution from a physiological sample
US7846321B2 (en) * 2006-10-18 2010-12-07 Agamatrix, Inc. Error detection in analyte measurements based on measurement of system resistance
US7771583B2 (en) * 2006-10-18 2010-08-10 Agamatrix, Inc. Electrochemical determination of analytes
JP5212990B2 (en) * 2007-03-28 2013-06-19 アークレイ株式会社 Analysis equipment
DE102007018383A1 (en) 2007-04-17 2008-10-23 Tesa Ag Sheet-like material with hydrophilic and hydrophobic areas and their production
AU2008265542B2 (en) 2007-06-21 2014-07-24 Abbott Diabetes Care Inc. Health monitor
US8597188B2 (en) 2007-06-21 2013-12-03 Abbott Diabetes Care Inc. Health management devices and methods
US7794658B2 (en) 2007-07-25 2010-09-14 Lifescan, Inc. Open circuit delay devices, systems, and methods for analyte measurement
EP2108125A1 (en) * 2007-09-05 2009-10-14 Lifescan Scotland Limited Strip for an electrochemical meter
DE502007000757D1 (en) * 2007-09-19 2009-07-02 Roche Diagnostics Gmbh Marking method for reject marking of test elements
US8778168B2 (en) 2007-09-28 2014-07-15 Lifescan, Inc. Systems and methods of discriminating control solution from a physiological sample
EP2205757B1 (en) * 2007-10-31 2017-06-14 Roche Diabetes Care GmbH Electrical patterns for biosensor and method of making
US8603768B2 (en) * 2008-01-17 2013-12-10 Lifescan, Inc. System and method for measuring an analyte in a sample
DE102008006225A1 (en) 2008-01-25 2009-07-30 Tesa Ag Biosensor and its production
EP3659628A1 (en) 2008-04-10 2020-06-03 Abbott Diabetes Care, Inc. Method and system for sterilizing an analyte sensor
US20090294277A1 (en) * 2008-05-30 2009-12-03 Abbott Diabetes Care, Inc. Method and system for producing thin film biosensors
US8551320B2 (en) 2008-06-09 2013-10-08 Lifescan, Inc. System and method for measuring an analyte in a sample
KR101003077B1 (en) 2008-10-16 2010-12-21 세종공업 주식회사 Electrochemical biosensor structure and measuring method using the same
US9402544B2 (en) 2009-02-03 2016-08-02 Abbott Diabetes Care Inc. Analyte sensor and apparatus for insertion of the sensor
WO2010138856A1 (en) 2009-05-29 2010-12-02 Abbott Diabetes Care Inc. Medical device antenna systems having external antenna configurations
BR112012000220A2 (en) 2009-08-31 2020-12-22 Abbott Diabetes Care Inc. METHODS AND MEDICAL DEVICES
DE102010002921A1 (en) * 2010-03-16 2011-09-22 Senslab-Gesellschaft Zur Entwicklung Und Herstellung Bioelektrochemischer Sensoren Mbh Microfluidic multiple measuring chamber arrangement
DK2658444T3 (en) * 2010-12-30 2015-02-16 Hoffmann La Roche Method of providing an effective biosensor, as well as corresponding biosensor, substrate and insertion equipment
EP3583901A3 (en) 2011-02-28 2020-01-15 Abbott Diabetes Care, Inc. Devices, systems, and methods associated with analyte monitoring devices and devices incorporating the same
US8888973B2 (en) 2011-07-29 2014-11-18 Roche Diagnostics Operations, Inc. Encoded biosensors and methods of manufacture and use thereof
US9754708B2 (en) 2011-07-29 2017-09-05 Roche Diabetes Care, Inc. Encoded biosensors and methods of manufacture and use thereof
DE102011109338B3 (en) * 2011-08-03 2013-01-31 Dietrich Reichwein Device for storing electromagnetic energy
US9069536B2 (en) 2011-10-31 2015-06-30 Abbott Diabetes Care Inc. Electronic devices having integrated reset systems and methods thereof
EP2803986B1 (en) 2012-01-13 2018-02-14 Panasonic Healthcare Holdings Co., Ltd. Biological sample measurement apparatus
KR101727422B1 (en) 2013-03-15 2017-04-14 에프. 호프만-라 로슈 아게 Methods of scaling data used to construct biosensor algorithms as well as devices, apparatuses and systems incorporating the same
CN105247357B (en) 2013-03-15 2017-12-12 豪夫迈·罗氏有限公司 It is horizontal with the therefrom method to analyte concentration fail-safe and with reference to its unit and system that high in antioxidants is detected during electrochemical measurement
KR101732300B1 (en) 2013-03-15 2017-05-02 에프. 호프만-라 로슈 아게 Methods of failsafing electrochemical measurements of an analyte as well as devices, apparatuses and systems incorporating the same
WO2014140164A1 (en) 2013-03-15 2014-09-18 Roche Diagnostics Gmbh Methods of using information from recovery pulses in electrochemical analyte measurements as well as devices, apparatuses and systems incorporating the same
KR101923797B1 (en) * 2014-06-05 2018-11-29 에프. 호프만-라 로슈 아게 Electrode arrangements for test element integrity
JP6526193B2 (en) 2014-11-03 2019-06-05 エフ ホフマン−ラ ロッシュ アクチェン ゲゼルシャフト Electrode arrangement for electrochemical test elements and method of use thereof
US9506890B2 (en) * 2014-12-16 2016-11-29 Eastman Chemical Company Physical vapor deposited biosensor components
JP6772249B2 (en) * 2015-08-11 2020-10-21 エフ ホフマン−ラ ロッシュ アクチェン ゲゼルシャフト Encoded biosensors and how to make and use them
AU2016383525A1 (en) * 2015-12-28 2018-05-31 Lifescan Scotland Limited Electrochemical-based analytical test strip with electrode voltage sensing connections and hand-held test meter for use therewith
JP6905543B2 (en) 2016-06-15 2021-07-21 イーストマン ケミカル カンパニー Physically vapor-deposited biosensor components
US11630075B2 (en) 2016-09-16 2023-04-18 Eastman Chemical Company Biosensor electrodes prepared by physical vapor deposition
EP3512957B1 (en) 2016-09-16 2022-03-09 Eastman Chemical Company Biosensor electrodes prepared by physical vapor deposition
EP3523639A4 (en) 2016-10-05 2020-06-03 H. Hoffnabb-La Roche Ag Detection reagents and electrode arrangements for multi-analyte diagnostic test elements, as well as methods of using the same
JP7133572B2 (en) 2017-06-22 2022-09-08 イーストマン ケミカル カンパニー Physical vapor deposition electrodes for electrochemical sensors

Family Cites Families (180)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3526480A (en) 1966-12-15 1970-09-01 Xerox Corp Automated chemical analyzer
US3551295A (en) 1967-11-29 1970-12-29 Northrop Corp Microbiological detection and identification system
US3621381A (en) 1968-10-16 1971-11-16 Leeds & Northrup Co Coulometric system having compensation for temperature induced viscosity changes
BE754658A (en) 1969-08-12 1971-02-10 Merck Patent Gmbh INDICATOR SHEET, CONSISTING OF AN IMPREGNATED, ABSORBENT, SHEATHED HAIR MATERIAL
US3770607A (en) 1970-04-07 1973-11-06 Secretary Glucose determination apparatus
US3919627A (en) 1970-08-06 1975-11-11 Gerald F Allen Conductivity measuring method and apparatus utilizing coaxial electrode cells
US3776832A (en) 1970-11-10 1973-12-04 Energetics Science Electrochemical detection cell
US3720093A (en) 1970-12-03 1973-03-13 Us Navy Carbon dioxide indicating meter
CH559912A5 (en) 1971-09-09 1975-03-14 Hoffmann La Roche
US3763422A (en) 1971-10-21 1973-10-02 Corning Glass Works Method and apparatus for electrochemical analysis of small samples of blood
US3925183A (en) 1972-06-16 1975-12-09 Energetics Science Gas detecting and quantitative measuring device
US3902970A (en) 1973-07-30 1975-09-02 Leeds & Northrup Co Flow-through amperometric measuring system and method
CH585907A5 (en) 1973-08-06 1977-03-15 Hoffmann La Roche
US3937615A (en) 1974-12-17 1976-02-10 Leeds & Northrup Company Auto-ranging glucose measuring system
FR2295419A1 (en) 1974-12-21 1976-07-16 Kyoto Daiichi Kagaku Kk REFLECTANCE MEASURING DEVICE AND COMPOSITE TEST PAPER STRUCTURE SUBJECT TO SUCH MEASUREMENT
US4052596A (en) 1974-12-23 1977-10-04 Hycel, Inc. Automatic hematology analyzer
US4008448A (en) 1975-10-03 1977-02-15 Polaroid Corporation Solenoid with selectively arrestible plunger movement
US4230537A (en) 1975-12-18 1980-10-28 Monsanto Company Discrete biochemical electrode system
US4040908A (en) 1976-03-12 1977-08-09 Children's Hospital Medical Center Polarographic analysis of cholesterol and other macromolecular substances
US4065263A (en) 1976-04-02 1977-12-27 Woodbridge Iii Richard G Analytical test strip apparatus
US4053381A (en) 1976-05-19 1977-10-11 Eastman Kodak Company Device for determining ionic activity of components of liquid drops
US4123701A (en) 1976-07-01 1978-10-31 United States Surgical Corporation Disposable sample card having a well with electrodes for testing a liquid sample
US4127448A (en) 1977-02-28 1978-11-28 Schick Karl G Amperometric-non-enzymatic method of determining sugars and other polyhydroxy compounds
JPS5912135B2 (en) 1977-09-28 1984-03-21 松下電器産業株式会社 enzyme electrode
JPS5460996A (en) 1977-10-22 1979-05-16 Mitsubishi Chem Ind Method of measuring amount of sugar
US4214968A (en) 1978-04-05 1980-07-29 Eastman Kodak Company Ion-selective electrode
DE2817363C2 (en) 1978-04-20 1984-01-26 Siemens AG, 1000 Berlin und 8000 München Method for determining the concentration of sugar and a suitable electrocatalytic sugar sensor
DE2823485C2 (en) 1978-05-30 1986-03-27 Albert Prof. Dr. 3550 Marburg Huch Trough electrode
US4184936A (en) 1978-07-24 1980-01-22 Eastman Kodak Company Device for determining ionic activity
US4233029A (en) 1978-10-25 1980-11-11 Eastman Kodak Company Liquid transport device and method
US4225410A (en) 1978-12-04 1980-09-30 Technicon Instruments Corporation Integrated array of electrochemical sensors
US4329642A (en) 1979-03-09 1982-05-11 Siliconix, Incorporated Carrier and test socket for leadless integrated circuit
US4273134A (en) 1979-05-22 1981-06-16 Biochem International Inc. Fixation ring assembly and method of assembling a sensor head
US4273639A (en) 1979-06-20 1981-06-16 Eastman Kodak Company Capillary bridge in apparatus for determining ionic activity
US4297569A (en) 1979-06-28 1981-10-27 Datakey, Inc. Microelectronic memory key with receptacle and systems therefor
US4265250A (en) 1979-07-23 1981-05-05 Battle Research And Development Associates Electrode
US4263343A (en) 1979-08-13 1981-04-21 Eastman Kodak Company Reference elements for ion-selective membrane electrodes
US4301412A (en) 1979-10-29 1981-11-17 United States Surgical Corporation Liquid conductivity measuring system and sample cards therefor
US4303887A (en) 1979-10-29 1981-12-01 United States Surgical Corporation Electrical liquid conductivity measuring system
US4628193A (en) 1980-01-30 1986-12-09 Blum Alvin S Code reading operations supervisor
US4323536A (en) 1980-02-06 1982-04-06 Eastman Kodak Company Multi-analyte test device
US4413407A (en) 1980-03-10 1983-11-08 Eastman Kodak Company Method for forming an electrode-containing device with capillary transport between electrodes
DE3029579C2 (en) 1980-08-05 1985-12-12 Boehringer Mannheim Gmbh, 6800 Mannheim Method and means for separating plasma or serum from whole blood
US4816224A (en) 1980-08-05 1989-03-28 Boehringer Mannheim Gmbh Device for separating plasma or serum from whole blood and analyzing the same
US4407959A (en) 1980-10-29 1983-10-04 Fuji Electric Co., Ltd. Blood sugar analyzing apparatus
US4413628A (en) 1980-11-19 1983-11-08 Tamulis Walter G pH Monitor electrode electrolyte cartridge
US4420564A (en) 1980-11-21 1983-12-13 Fuji Electric Company, Ltd. Blood sugar analyzer having fixed enzyme membrane sensor
DE3047782A1 (en) 1980-12-18 1982-07-08 Drägerwerk AG, 2400 Lübeck CIRCUIT FOR THE CORRECTION OF THE SENSOR OUTPUT SIZE
US4436094A (en) 1981-03-09 1984-03-13 Evreka, Inc. Monitor for continuous in vivo measurement of glucose concentration
US4407290A (en) 1981-04-01 1983-10-04 Biox Technology, Inc. Blood constituent measuring device and method
AT369254B (en) 1981-05-07 1982-12-27 Otto Dipl Ing Dr Tech Prohaska MEDICAL PROBE
US4440175A (en) 1981-08-10 1984-04-03 University Patents, Inc. Membrane electrode for non-ionic species
DE3133826A1 (en) 1981-08-27 1983-03-10 Boehringer Mannheim Gmbh, 6800 Mannheim ANALYSIS TEST STRIP AND METHOD FOR THE PRODUCTION THEREOF
DE3137174A1 (en) 1981-09-18 1983-04-07 Boehringer Mannheim Gmbh, 6800 Mannheim DEVICE FOR THE OPTICAL DETECTION OF A CODING ON A DIAGNOSTIC TEST STRIP
EP0078636B2 (en) 1981-10-23 1997-04-02 MediSense, Inc. Sensor for components of a liquid mixture
US4431004A (en) 1981-10-27 1984-02-14 Bessman Samuel P Implantable glucose sensor
NZ199380A (en) 1981-12-23 1986-08-08 J R Baker Determination of serum glucose levels in blood samples
DE3202067C2 (en) 1982-01-23 1984-06-20 Holger Dr. 5100 Aachen Kiesewetter Device for determining the hematocrit value
DE3228551A1 (en) 1982-07-30 1984-02-02 Siemens AG, 1000 Berlin und 8000 München METHOD FOR DETERMINING SUGAR CONCENTRATION
DE3228542A1 (en) 1982-07-30 1984-02-02 Siemens AG, 1000 Berlin und 8000 München METHOD FOR DETERMINING THE CONCENTRATION OF ELECTROCHEMICALLY IMPLEMENTABLE SUBSTANCES
US4571292A (en) 1982-08-12 1986-02-18 Case Western Reserve University Apparatus for electrochemical measurements
US4679562A (en) 1983-02-16 1987-07-14 Cardiac Pacemakers, Inc. Glucose sensor
CA1219040A (en) 1983-05-05 1987-03-10 Elliot V. Plotkin Measurement of enzyme-catalysed reactions
DE3326689A1 (en) 1983-07-23 1985-01-31 Boehringer Mannheim Gmbh, 6800 Mannheim METHOD AND DEVICE FOR PRODUCING A TEST STRIP
US4517291A (en) 1983-08-15 1985-05-14 E. I. Du Pont De Nemours And Company Biological detection process using polymer-coated electrodes
US4552458A (en) 1983-10-11 1985-11-12 Eastman Kodak Company Compact reflectometer
SE8305704D0 (en) 1983-10-18 1983-10-18 Leo Ab Cuvette
US4703017C1 (en) 1984-02-14 2001-12-04 Becton Dickinson Co Solid phase assay with visual readout
DE3407754A1 (en) 1984-03-02 1985-09-12 Boehringer Mannheim Gmbh, 6800 Mannheim DEVICE FOR DETERMINING THE DIFFUSION REFLECTIVITY OF A SAMPLE AREA OF SMALL DIMENSIONS
US4849330A (en) 1984-04-27 1989-07-18 Molecular Devices Corporation Photoresponsive redox detection and discrimination
US4820399A (en) 1984-08-31 1989-04-11 Shimadzu Corporation Enzyme electrodes
US4648665A (en) 1984-10-16 1987-03-10 Amp Incorporated Electronic key assemblies
US4713347A (en) 1985-01-14 1987-12-15 Sensor Diagnostics, Inc. Measurement of ligand/anti-ligand interactions using bulk conductance
GB8504521D0 (en) 1985-02-21 1985-03-27 Genetics Int Inc Electrochemical assay
US5279294A (en) * 1985-04-08 1994-01-18 Cascade Medical, Inc. Medical diagnostic system
US4652830A (en) 1985-04-18 1987-03-24 Eg&G Ocean Products, Inc. Analyzer for comparative measurements of bulk conductivity
US4671288A (en) 1985-06-13 1987-06-09 The Regents Of The University Of California Electrochemical cell sensor for continuous short-term use in tissues and blood
US4897173A (en) 1985-06-21 1990-01-30 Matsushita Electric Industrial Co., Ltd. Biosensor and method for making the same
US4686479A (en) 1985-07-22 1987-08-11 Young Chung C Apparatus and control kit for analyzing blood sample values including hematocrit
US4806311A (en) 1985-08-28 1989-02-21 Miles Inc. Multizone analytical element having labeled reagent concentration zone
US4806312A (en) 1985-08-28 1989-02-21 Miles Inc. Multizone analytical element having detectable signal concentrating zone
US4734184A (en) 1985-08-29 1988-03-29 Diamond Sensor Systems, Inc. Self-activating hydratable solid-state electrode apparatus
US4805624A (en) 1985-09-09 1989-02-21 The Montefiore Hospital Association Of Western Pa Low-potential electrochemical redox sensors
EP0215669A3 (en) 1985-09-17 1989-08-30 Seiko Instruments Inc. Analytical device and method for analysis of biochemicals, microbes and cells
US5500350A (en) * 1985-10-30 1996-03-19 Celltech Limited Binding assay device
US4714874A (en) 1985-11-12 1987-12-22 Miles Inc. Test strip identification and instrument calibration
US4795542A (en) 1986-04-24 1989-01-03 St. Jude Medical, Inc. Electrochemical concentration detector device
US4703756A (en) 1986-05-06 1987-11-03 The Regents Of The University Of California Complete glucose monitoring system with an implantable, telemetered sensor module
US4731726A (en) 1986-05-19 1988-03-15 Healthware Corporation Patient-operated glucose monitor and diabetes management system
US4750496A (en) 1987-01-28 1988-06-14 Xienta, Inc. Method and apparatus for measuring blood glucose concentration
JPS636451A (en) 1986-06-27 1988-01-12 Terumo Corp Enzyme sensor
US4935346A (en) * 1986-08-13 1990-06-19 Lifescan, Inc. Minimum procedure system for the determination of analytes
US4865873A (en) 1986-09-15 1989-09-12 General Electric Company Electroless deposition employing laser-patterned masking layer
US4897162A (en) 1986-11-14 1990-01-30 The Cleveland Clinic Foundation Pulse voltammetry
JPH039267Y2 (en) 1986-12-27 1991-03-07
GB2201248B (en) 1987-02-24 1991-04-17 Ici Plc Enzyme electrode sensors
US4759828A (en) 1987-04-09 1988-07-26 Nova Biomedical Corporation Glucose electrode and method of determining glucose
DE3715938A1 (en) 1987-05-13 1988-11-24 Boehringer Mannheim Gmbh CONTAINER FOR TEST STRIP
US4797256A (en) 1987-06-05 1989-01-10 Boehringer Mannheim Corporation Registration device for blood test strips
US4832814A (en) 1987-12-28 1989-05-23 E. I. Du Pont De Nemours And Company Electrofusion cell and method of making the same
US4877580A (en) 1988-02-09 1989-10-31 Technimed Corporation Assay kit including an analyte test strip and a color comparator
US5096669A (en) * 1988-09-15 1992-03-17 I-Stat Corporation Disposable sensing device for real time fluid analysis
US4999582A (en) * 1989-12-15 1991-03-12 Boehringer Mannheim Corp. Biosensor electrode excitation circuit
US4999632A (en) * 1989-12-15 1991-03-12 Boehringer Mannheim Corporation Analog to digital conversion with noise reduction
CA2069946C (en) * 1989-12-15 1999-01-26 Klaus H. Pollmann Redox mediator reagent and biosensor
US5286362A (en) * 1990-02-03 1994-02-15 Boehringer Mannheim Gmbh Method and sensor electrode system for the electrochemical determination of an analyte or an oxidoreductase as well as the use of suitable compounds therefor
US5187100A (en) * 1990-05-29 1993-02-16 Lifescan, Inc. Dispersion to limit penetration of aqueous solutions into a membrane
US5182707A (en) * 1990-07-23 1993-01-26 Healthdyne, Inc. Apparatus for recording reagent test strip data by comparison to color lights on a reference panel
DE4041905A1 (en) * 1990-12-27 1992-07-02 Boehringer Mannheim Gmbh TEST CARRIER ANALYSIS SYSTEM
DE69233262T2 (en) * 1991-02-27 2004-09-30 Roche Diagnostics Corp., Indianapolis Device and method for analyzing body fluids
DE69232284T2 (en) * 1991-02-27 2002-06-13 Roche Diagnostics Corp TRANSFER PROCEDURE WITH MICRO COMPUTER CONTROLLED INSTRUMENTS
US5192415A (en) * 1991-03-04 1993-03-09 Matsushita Electric Industrial Co., Ltd. Biosensor utilizing enzyme and a method for producing the same
US5593852A (en) * 1993-12-02 1997-01-14 Heller; Adam Subcutaneous glucose electrode
GB9113211D0 (en) * 1991-06-19 1991-08-07 Hypoguard Uk Ltd Support membrane
US5179288A (en) * 1991-09-30 1993-01-12 Ortho Pharmaceutical Corporation Apparatus and method for measuring a bodily constituent
US5605662A (en) * 1993-11-01 1997-02-25 Nanogen, Inc. Active programmable electronic devices for molecular biological analysis and diagnostics
US5296192A (en) * 1992-04-03 1994-03-22 Home Diagnostics, Inc. Diagnostic test strip
US5389215A (en) * 1992-11-05 1995-02-14 Nippon Telegraph And Telephone Corporation Electrochemical detection method and apparatus therefor
US6168563B1 (en) * 1992-11-17 2001-01-02 Health Hero Network, Inc. Remote health monitoring and maintenance system
US5371687A (en) * 1992-11-20 1994-12-06 Boehringer Mannheim Corporation Glucose test data acquisition and management system
FR2701117B1 (en) * 1993-02-04 1995-03-10 Asulab Sa Electrochemical measurement system with multizone sensor, and its application to glucose measurement.
ATE186232T1 (en) * 1993-04-23 1999-11-15 Roche Diagnostics Gmbh SYSTEM FOR STOCKING AND PROVIDING TEST ELEMENTS
US5385846A (en) * 1993-06-03 1995-01-31 Boehringer Mannheim Corporation Biosensor and method for hematocrit determination
DE702789T1 (en) * 1993-06-08 2000-11-02 Roche Diagnostics Corp BIO KNIFE FOR DETECTING CORRECT ELECTRODE COUPLING AND FOR DISTINATING BETWEEN TEST AND REFERENCE STRIPS
US5522255A (en) * 1993-08-31 1996-06-04 Boehringer Mannheim Corporation Fluid dose, flow and coagulation sensor for medical instrument
US5536249A (en) * 1994-03-09 1996-07-16 Visionary Medical Products, Inc. Pen-type injector with a microprocessor and blood characteristic monitor
US6335203B1 (en) * 1994-09-08 2002-01-01 Lifescan, Inc. Optically readable strip for analyte detection having on-strip orientation index
US5597532A (en) * 1994-10-20 1997-01-28 Connolly; James Apparatus for determining substances contained in a body fluid
EP0727925A1 (en) * 1995-02-14 1996-08-21 Lpkf Cad/Cam Systeme Gmbh Process for structured metallizing of the surface of substrates
US6170318B1 (en) * 1995-03-27 2001-01-09 California Institute Of Technology Methods of use for sensor based fluid detection devices
JP3498105B2 (en) * 1995-04-07 2004-02-16 アークレイ株式会社 Sensor, method for manufacturing the same, and measuring method using the sensor
JPH08336399A (en) * 1995-06-13 1996-12-24 Oki Electric Ind Co Ltd Detection of arginine and arginine sensor
US5873990A (en) * 1995-08-22 1999-02-23 Andcare, Inc. Handheld electromonitor device
AUPN661995A0 (en) * 1995-11-16 1995-12-07 Memtec America Corporation Electrochemical cell 2
US6521110B1 (en) * 1995-11-16 2003-02-18 Lifescan, Inc. Electrochemical cell
US6174420B1 (en) * 1996-11-15 2001-01-16 Usf Filtration And Separations Group, Inc. Electrochemical cell
JPH09159644A (en) * 1995-12-11 1997-06-20 Dainippon Printing Co Ltd Biosensor and manufacture thereof
US5708247A (en) * 1996-02-14 1998-01-13 Selfcare, Inc. Disposable glucose test strips, and methods and compositions for making same
US5605837A (en) * 1996-02-14 1997-02-25 Lifescan, Inc. Control solution for a blood glucose monitor
US6001307A (en) * 1996-04-26 1999-12-14 Kyoto Daiichi Kagaku Co., Ltd. Device for analyzing a sample
DE19621241C2 (en) * 1996-05-25 2000-03-16 Manfred Kessler Membrane electrode for measuring the glucose concentration in liquids
US5719667A (en) * 1996-07-30 1998-02-17 Bayer Corporation Apparatus for filtering a laser beam in an analytical instrument
US5856195A (en) * 1996-10-30 1999-01-05 Bayer Corporation Method and apparatus for calibrating a sensor element
US6013459A (en) * 1997-06-12 2000-01-11 Clinical Micro Sensors, Inc. Detection of analytes using reorganization energy
US6168957B1 (en) * 1997-06-25 2001-01-02 Lifescan, Inc. Diagnostic test strip having on-strip calibration
US5859917A (en) * 1997-08-04 1999-01-12 Infinity Systems Inc. Flush-mount swivel tweeter system for vehicular audio
JPH1164271A (en) * 1997-08-18 1999-03-05 Nagoyashi Current amplification type oxyzen sensor
US6071391A (en) * 1997-09-12 2000-06-06 Nok Corporation Enzyme electrode structure
EP2085779B1 (en) * 1997-12-22 2017-11-01 Roche Diagnostics Operations, Inc. Meter
JP3978489B2 (en) * 1998-02-26 2007-09-19 アークレイ株式会社 Blood measuring device
EP0987544B1 (en) * 1998-04-02 2007-10-17 Matsushita Electric Industrial Co., Ltd. Substrate determining method
US6175752B1 (en) * 1998-04-30 2001-01-16 Therasense, Inc. Analyte monitoring device and methods of use
US6526298B1 (en) * 1998-05-18 2003-02-25 Abbott Laboratories Method for the non-invasive determination of analytes in a selected volume of tissue
JP3389106B2 (en) * 1998-06-11 2003-03-24 松下電器産業株式会社 Electrochemical analysis element
US6294281B1 (en) * 1998-06-17 2001-09-25 Therasense, Inc. Biological fuel cell and method
AU4833799A (en) * 1998-06-24 2000-01-10 Therasense, Inc. Combinatorial electrochemical syntheses
US6521182B1 (en) * 1998-07-20 2003-02-18 Lifescan, Inc. Fluidic device for medical diagnostics
US6180416B1 (en) * 1998-09-30 2001-01-30 Cygnus, Inc. Method and device for predicting physiological values
US6193873B1 (en) * 1999-06-15 2001-02-27 Lifescan, Inc. Sample detection to initiate timing of an electrochemical assay
US6514769B2 (en) * 1999-07-29 2003-02-04 Jin Po Lee Multiple analyte assay device with sample integrity monitoring system
DE19936693A1 (en) * 1999-08-04 2001-02-08 Lre Technology Partner Gmbh Instrument for the measurement of blood sugar concentrations has a test field with electrodes for the test strip and a circuit for measurement/evaluation of the current strength for display
US6662439B1 (en) * 1999-10-04 2003-12-16 Roche Diagnostics Corporation Laser defined features for patterned laminates and electrodes
WO2001038862A1 (en) * 1999-11-22 2001-05-31 Matsushita Electric Industrial Co., Ltd. Cholesterol sensor and method for determining cholesterol
JP2001159618A (en) * 1999-12-03 2001-06-12 Matsushita Electric Ind Co Ltd Biosensor
DK1311702T3 (en) * 2000-03-28 2006-03-27 Diabetes Diagnostics Inc Continuous process for producing a disposable electrochemical sensing element
TW548095B (en) * 2000-06-01 2003-08-21 Chih-Hui Lee Electrochemical electrode test piece and method for producing the same
JP2004501380A (en) * 2000-06-26 2004-01-15 ボストン　メディカル　テクノロジーズ　インコーポレイテッド Glucose measurement system
DE10032775B4 (en) * 2000-07-06 2007-06-14 Endress + Hauser Gmbh + Co. Kg Device for determining and / or monitoring the fill level of a product in a container
US6561989B2 (en) * 2000-07-10 2003-05-13 Bayer Healthcare, Llc Thin lance and test sensor having same
DE60140000D1 (en) * 2000-07-24 2009-11-05 Panasonic Corp Biosensor
US6512986B1 (en) * 2000-12-30 2003-01-28 Lifescan, Inc. Method for automated exception-based quality control compliance for point-of-care devices
US6525330B2 (en) * 2001-02-28 2003-02-25 Home Diagnostics, Inc. Method of strip insertion detection
EP1288654B1 (en) * 2001-05-29 2008-10-22 Matsushita Electric Industrial Co., Ltd. Biosensor
US20030036202A1 (en) * 2001-08-01 2003-02-20 Maria Teodorcyzk Methods and devices for use in analyte concentration determination assays
US6689411B2 (en) * 2001-11-28 2004-02-10 Lifescan, Inc. Solution striping system
CN1467496A (en) * 2002-06-03 2004-01-14 松下电器产业株式会社 Biosensor
US20040241131A1 (en) * 2003-05-29 2004-12-02 Unilever Home & Personal Care Usa, Division Of Conopco, Inc. Compositions containing malonate salts in preventing in-grown hair arising from shaving
EP1642125B1 (en) * 2003-06-20 2017-09-27 Roche Diabetes Care GmbH Biosensor with multiple electrical functionalities
US7452457B2 (en) * 2003-06-20 2008-11-18 Roche Diagnostics Operations, Inc. System and method for analyte measurement using dose sufficiency electrodes
US7569126B2 (en) * 2004-06-18 2009-08-04 Roche Diagnostics Operations, Inc. System and method for quality assurance of a biosensor test strip

Also Published As

Publication number Publication date
CN101103271A (en) 2008-01-09
EP1846761B1 (en) 2017-07-19
US20050284758A1 (en) 2005-12-29
CN101103271B (en) 2011-11-16
US7556723B2 (en) 2009-07-07
WO2006074927A1 (en) 2006-07-20
HK1115440A1 (en) 2008-11-28
CA2594417C (en) 2011-04-12
EP1846761A1 (en) 2007-10-24
JP2008527341A (en) 2008-07-24
WO2006074927A8 (en) 2007-08-23
PL1846761T3 (en) 2017-12-29
JP4827855B2 (en) 2011-11-30
ES2644041T3 (en) 2017-11-27

Similar Documents

Publication Publication Date Title
CA2594417A1 (en) Novel electrode design for biosensor
JP2008527341A5 (en)
HK1096151A1 (en) Devices and methods relating to electrochemical biosensors
CN1867826B (en) Method and apparatus for assay of electrochemical properties
WO2008049074A3 (en) Error detection in analyte measurements based on measurement of system resistance
JP2007537456A5 (en)
WO2006109274A3 (en) Error detection in analyte measurements based on measurement of system resistance
WO2005119234A3 (en) Measuring device and methods for use therewith
DE60329218D1 (en) LIFE DETECTION BY FOUR-POINT MEASUREMENT OF THE COMPLEX IMPEDANCE
ATE391529T1 (en) ISCHEMIA DETECTOR
WO2004004662A3 (en) Compositions and methods for the diagnosis and treatment of tumor
WO2009031375A1 (en) Electrochemical sensor device and electrochemical measuring method using the same
WO2009031761A4 (en) Biosensor and readout meter
CN106442659B (en) The active method of electrochemical sensing electrode quantitative detection 8-OhdG based on aniline deposition
TW200624812A (en) Multiple axis acceleration sensor
Kraikaew et al. Rapid constant potential capacitive measurements with solid-contact ion-selective electrodes coupled to electronic capacitor
TW200739091A (en) System, circuit and method for measuring resistance of wheatstone bridge, and computer program
EP2270495A3 (en) Analyte test strip with combination electrode contact and meter identification feature
Graf et al. Advancements in capacitance‐to‐digital converter‐based C4D technology for detection in capillary electrophoresis using amplified excitation voltages and comparison to classical and open‐source C4Ds
JP2010535340A5 (en)
CN204072091U (en) A kind of probe for measuring bio-impedance
CN100520384C (en) Four-electrode original position soil salt content measuring method
CN100514049C (en) Original position soil salt content sensing transducer
CN101451973A (en) Combination three-electrode
CA2862183A1 (en) Low-conductivity contacting-type conductivity measurement

Legal Events

Date Code Title Description
EEER Examination request