CA2555464C - A medical connector and a method of injection moulding such a connector - Google Patents
A medical connector and a method of injection moulding such a connector Download PDFInfo
- Publication number
- CA2555464C CA2555464C CA2555464A CA2555464A CA2555464C CA 2555464 C CA2555464 C CA 2555464C CA 2555464 A CA2555464 A CA 2555464A CA 2555464 A CA2555464 A CA 2555464A CA 2555464 C CA2555464 C CA 2555464C
- Authority
- CA
- Canada
- Prior art keywords
- tube
- inner part
- connector
- connector according
- outer part
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M39/00—Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
- A61M39/10—Tube connectors; Tube couplings
- A61M39/12—Tube connectors; Tube couplings for joining a flexible tube to a rigid attachment
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C45/00—Injection moulding, i.e. forcing the required volume of moulding material through a nozzle into a closed mould; Apparatus therefor
- B29C45/16—Making multilayered or multicoloured articles
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
- F16L—PIPES; JOINTS OR FITTINGS FOR PIPES; SUPPORTS FOR PIPES, CABLES OR PROTECTIVE TUBING; MEANS FOR THERMAL INSULATION IN GENERAL
- F16L47/00—Connecting arrangements or other fittings specially adapted to be made of plastics or to be used with pipes made of plastics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M39/00—Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
- A61M39/10—Tube connectors; Tube couplings
- A61M2039/1027—Quick-acting type connectors
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C45/00—Injection moulding, i.e. forcing the required volume of moulding material through a nozzle into a closed mould; Apparatus therefor
- B29C45/0053—Injection moulding, i.e. forcing the required volume of moulding material through a nozzle into a closed mould; Apparatus therefor combined with a final operation, e.g. shaping
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C45/00—Injection moulding, i.e. forcing the required volume of moulding material through a nozzle into a closed mould; Apparatus therefor
- B29C45/16—Making multilayered or multicoloured articles
- B29C45/1657—Making multilayered or multicoloured articles using means for adhering or bonding the layers or parts to each other
Abstract
A medical connector for connecting a tube with a medical device and having a through-going bore which at one end of the connector comprises a cavity for permanently attaching the end of the tube to the connector and which at least at said end of the connector comprises an inner part and an outer part; the inner part and outer part being intregrally connected, the outer part being made from a thermoplastics material which is resistant to changes when subjected to the influence of a disinfectant and the inner part being made from a thermoplastics material which is compatible with a soft glue and a method for injection moulding of such connectors.
Description
A medical connector and a method of injection moulding such a connector This invention relates to a medical connector for connecting a tube to a medical device such as an insulin delivery device.
Such connectors are typically provided with means such as Luer-Lock type means.for connecting the end of the connector which is opposite to the end at which the tube is connected to the connector, to the medical device so as to allow the connector to be disengaged from said device, this allowing the medical device and/or the connector including the tube to be replaced.
EP 0 X53 323 A1 describes a coupling for joining the' ends of two tubes, said coupling comprising a male part and a female parfi, both the male and female part having means for attachment of the end of a tutae.
EP 0 151 519 describes a tube coupling comprising a male part and a female part, both the male part and the female part comprising a tapered tube connecting portion which is adapted to be inserted into the end of a tube.
EP 0 ~~5 501 13 describes a female coupling element of the Luer-Lock type comprising an outer tubular body which is made of a relatively rigid moulded thermoplastics mafierial and can be connected with a complimentary male coupling element, and an inner sleeve which is made of a softer moulded thermoplastics material which at one end is fitted within the outer body in such a manner that the two parts are freely rotatable relative to each other and at the opposite end comprises a cavity for connection to e.g. a tube.
Furthermore, medical connectors consisting of a single plastics material and manufactured by injection moulding are known.
Such medical connectors comprise a through-going bore, one end of said connector being adapted to be connected with the end of a tube by gluing so as to form a permanent connection and the opposite end comprising a part of a Luer-Lock type connection for connecting the connector to a medical device such as an insulin pump.
Due to the fact that an injection moulding process is a simple manufacturing method, such medical connectors can be manufactured at low costs.
However, these medical connectors suffer from a drawback.
Thus, prior to the use of a medical connector it has to be disinfected which ordinarily is effected by wiping it with a liquid disinfectant such as ethyl alcohol.
Such a treatmenfi may cause stresses in some plastics material to be released during physical strain and may result in the formation of cracks which bring aboufi leaks.
The selection of a plastics material which is resisfianfi to fibs influence of disinfecfianfis may cause another problem, vii. thafi fibs permanent connection of fibs fiube end to fibs connecfior has to be effiecfied by means of a~ hard glue.
The use of a hard glue in confirasfi to a soft glue resulfis in an inflexible connecfiion between fibs tube and fibs connecfior and may resulfi in a leakage.
In the previously known connecfiors composed of two plastics materials, such as those described in EP 0 775 501 B, the two parts have to be made separafiely and be assembled afterwards. This increases the production costs compared to connectors which can be injection moulded in one-piece.
The object of the present invention is to provide a medical connector which can be manufactured in large quantities at low costs and which is more resistant to leakage than the prior art medical connectors.
According to the invention there is provided a medical connector of the above mentioned type having a through-going bore which at one end of the connector comprises a cavity for permanently attaching the end of the tube to the connector and which at least at said end of the connector comprises an inner part and an outer part; the inner and outer parts being integrally connected, the outer part being made from a thermoplastics material which is resistant to changes when subjected to the influence of a disinfectant and the inner part being made from a thermoplastics material which is compatible with a soft glue.
The term integrally connected is to be understood as the two parts are connected in such way that they are unable to rotate independently around the longitudinal axis.
This new type of connectors is easy and cheap to produce. They are resistant to the mandatory disinfection prior to use and they have a flexible but permanent attachment of the tube to the connector.
According to fihe invention there is further provided a method for injection moulding of a connector of the above mentioned type comprising the steps of - injecting a plastics material which is compatible with a soft glue into a mould having a cavity of the desired shape and a core of the desired shape for forming a cavity in the connector for permanently atfiaching an end of a tube - injecting a plastics material which is resistant to changes when subjected to the influence of a disinfectant infix a mould having a cavity of the desired shape, a core for creating a through-going opening - using a part of the surface of the firstly injected plastics material as part of the mould receiving the secondly injected plastics material.
In one embodiment of the invention the connector comprises means for connecting the connector to a medical device such as an insulin pump, said means preferably being in form of a Luer-Lock type, and more preferably the means are capable of receiving the male part of the Luer-Lock type.
In a preferred embodiment the term integrally connected further implies that the two parts are unable to move independently along the length axis.
Preferably the connector comprises means for getting a better hold of the connector, which can be advantageous when connecting or disconnecting the connector to a medical device. Said means can be but are not limited to a groove, a ribbon, a rim, preferably the means are in form of a groove.
Preferably said means are placed in the same end as fihe tube is supposed to be attached.
In another embodiment of the invention the inner part and the outer part of the connector are capable of rocking relative to each other thereby providing a more flexible but still permanent connection to the tube. This reduces the risk of leakage even further.
In a preferred embodiment the cavity of the inner part of the connector has an increasing diameter towards the outer end of the inner part, preferably a part of the cavity has a conical shape. Preferably, the conical part forms an angle of at least 15 degrees relative to the central axis, preferably the angle is between 20 and 25 degrees.
In another embodiment the cavity of the outer part at the end receiving the tube also has an increasing diameter towards the outer end. Preferably at least a part of the cavity of the outer part has a conical shape.
By using a conical-shaped cavity of the inner part and/or a cavity of the outer part with an increasing diameter an even more flexible connection between the connector and the tube can be achieved. Further, the increasing diameter leaves more room for the soft and elastic glue.
In a preferred embodiment the diameter of the cavity of the inner part is 5 adapted to the diameter of the tube supposed to be permanently connected with the connector.
Preferably the connector is constructed in such way that the inner part at least in the area of connection between the connector and the tube is unable to come into contact with the disinfectants. Preferably the plastics material of the inner part is selected exclusively from its gluing properties i.e. it is compatible with a soft glue.
In one embodiment of the invention the delimiting part of the edge is flush with the delimiting edge of the outer part or even broaches there around and encloses portions of the outer faces of the outer part. In this case what matters is that a sealing is provided to prevent the liquid from penetrating from the outside and into the connecting area between the tube and the inner part.
In another embodiment the outer part is moulded in such way that it encloses the outer faces of the inner part so that during wiping with a disinfectant connection between the disinfectant and the inner part of the connector cannot be provided.
The connector with its permanently attached tube is preferably intended for use for infusion kits where the luer lock is mounted to an insulin pump, while the tube as such is connected to a syringe and an infusion part.
In another preferred embodiment the inner part and/or the outer part comprises fasteners for fastening the inner part to the outer part or visa versa, more preferably the inner part has retention devices and the outer part has grooves adapted to receive said retention devices. In an even more preferred embodiment the retention devices are mounted on the outside of the inner part and thereby providing a good retention between the inner part and the outer part ensuring that the inner part cannot be loosened.
In another embodiment the inner part and the outer part are connected and/or held together by means of a glue.
In another preferred embodiment the inner parfi, the glue and an area of the tube are capable of forming an integral chemical connection.
Preferably the soft glue used in the permanenfi connection betv~een the tube and the connector as a minimum has contact to both the tube and the inner ~ 5 part. It is of no consequence whether the glue further has contact to the outer part or not, it is only importanfi that the connection has an inner area which is unable to come into contact with the disinfectant used to wipe the connector prior to use.
In a preferred embodiment the through-going bore of the outer part has a central axis which is axially parallel and coincident with the central axis of the inner part.
In a preferred embodiment both the inner part and the outer part are made of a thermoplastic material. In a more preferred embodiment the inner part is made of an amorphous plastics material, preferably with a molecular structure in which the chains are positioned randomly.
In a preferred embodiment the inner part is made of ABS. ABS is made of the monomer components acrylic nitrite, butadiene and styrene. Each of the three structural units adds valuable properties to the material. Acrylic nitrite is responsible for the resistance and dimensional stability in heat. Butadiene equips the material with tenacity and makes it resistant to impacts, while styrene serves to ensure the rigidity of the material and easy processability.
ABS tolerates a number of acids, bases and oils with the proviso, however, that the level of internal stresses is very low. There are a number of solvents that can dissolve ABS. Other suitable amorphous plastics materials include e.g. polycarbonate, polystyrene, acrylic plastics, poly-methyl-methacrylate and PVG.
In another preferred embodiment the outer part is made of a plastics material also being a thermoplastics material and composed of at least one partially plastics material, preferably a polypropylene is used. Polypropylene is a partially crystalline plastics material in which the molecule chains are located in parallel with each other and form rather closely packed areas, the so-~ 5 called crystallites. Polypropylene is a thermoplastics material with an attractive balance between fihermal and chemical resistance and good mechanical and electrical properties. Furthermore, polypropylene is immune to bacteria and fungi. Additionally polypropylene is a plastics material having a very wide-ranging resistance to chemicals. It is resistant to salts, acids, ~0 bases (inorganic) and alcohols and some oils. In principle, it is the crystallite that is decisive to the resistance to chemicals. Also other materials can be used for the outer part e.g. polyamide, polyethylene, poly-ethylene-ether-ketone (PEEK).
~5 A crystalline plastics material is characterised in that the molecules are situated closely adjoining each other whereby the intermolecular forces act more strongly and more energy is to be supplied in order to overcome it. In practice this means that crystalline plastics/partially crystalline plastics generally have a higher temperature of vitrification and a higher melting point 30 than amorphous materials. The crystalline areas in the material have a distributing effect on light and therefore crystalline and partially crystalline plastics have a milky appearance.
A thermoplastics material has the characteristic feature that it exhibits three different, more or less sharply delimiting state areas as a function of the temperature, viz. a solid state, a rubber elastic state and a viscous state.
Upon heating the material becomes soft and assumes a rather more solid structure upon cooling and, in principle, it is possible to shape it several times.
The following physical, mechanical properties apply to a soft glue versus a hard glue.
~~ft glue Hard Tae Extension at 120/~-240/~0/~-50/~
break Hardness shore ~25-~60 ~65-~90 ~
In a preferred embodiment the connector is adapted to receive means for supporting the attachment of the tube. Said means are suitable for securing the tube to the connector until the glue is hardened.
~uring attachment of the tube to the connector it is preferred to have a final hardening after the glue is mounted between the connector and the tube.
Further it is preferred that the connector is adapted to firap and secure the tube until the glue has set.
The invention also relates to an infusion unit manufactured from the connector and wherein the end opposite to the tube is connected to an insulin pump by means of a luer-lock and wherein a soft glue is used to connect the tube to the connector.
In a preferred method of producing said connectors a plastics material which is compatible with a soft glue is injected into the mould under a suitable pressure for providing the inner part, subsequently under a suitable second pressure a plastics material being resistant to changes when subjected to the influence of a disinfectant is injected into the mould. Following such moulding of the connector, said moulding taking place e.g. in accordance with principles like the ones given in patent f'Jo. W~ 00/73040 and W~ 93/35303, an opening of the mould takes place and the connectors are ejected from their cores. ~ptionally a subsequent assembly process between the connector and a tube takes place as described above by means of a soft glue.
15' In the following a preferred embodiment of the invention will be described with reference to the figures.
Figures 1A-~ show an example of a connecting element according fio the ~0 invention seen from two different sides;
Figure 2 is a sectional view along II-II in Figure 1A;
Figure 3 is a sectional view of the outer part in detailed form;
Figure 4 is a sectional view of the inner part in detailed form;
Figure 5 shows the disclosures of Figure 2 with a plastics tube mounted in the inner part.
Figures 1A and 1 B show a connector 1, seen from the side in a first position and turned by 90°. The connector, see also Figure 2, comprises an outer part 2 which is preferably made of a thermoplastics material that is chemically resistant to disinfectant such as ethyl alcohol. The outer part comprises an 5 end 4 for receiving a tube and an end 5 for connecting to a medical device such as an insulin pump. The end 4 for receiving a tube comprises a cavity 6 as it is also seen in the sectional view in Figure 2.
The end 5 for connecting to a medical device comprises a luer lock 21 in 10 which a male luer-lock is preferably used. Finally the end 5 comprises an external double-thread 29 for being mounted to preferably an insulin pump.
The outer shape of the connector 1 is such that it is essentially cylindrically shaped, beat wherein the end 4~ for receiving fihe tube has a narrowed portion for providing an oval narrowing area 23. This serves to improve the gripping around the connector° 1 during handling thereof. The outer part 2 has an outer essentially plane upper delimiting face 20. The distance from this and down to the lower delimiting face 34 is within the range 17 mm.
Figure 2 is a sectional ~siew wherein the joining between the two elements that constitute the connecfior 1 vii. the oufier part 2 and the inner part 9 will appear. The outer part is manufactured such that there is liquid communication throughout its entire passage and it comprises axially a passage throughout its entire interior, wherein, in its end 5, it has such shape that it forms a leer lock 21. From said luer lock 21 an axial opening 3 fio the cavity 6 is provided. The central axis of the opening 3 is axially parallel and coinciding with a through-going opening 10 provided in the inner part 9. In the opposite end of the inner part 9 there is a section called the connector part 32 for the tube which is configured with side faces that diverge outwards towards an upper delimiting face 17, where said delimiting face 17 is of plane configuration.
Such connectors are typically provided with means such as Luer-Lock type means.for connecting the end of the connector which is opposite to the end at which the tube is connected to the connector, to the medical device so as to allow the connector to be disengaged from said device, this allowing the medical device and/or the connector including the tube to be replaced.
EP 0 X53 323 A1 describes a coupling for joining the' ends of two tubes, said coupling comprising a male part and a female parfi, both the male and female part having means for attachment of the end of a tutae.
EP 0 151 519 describes a tube coupling comprising a male part and a female part, both the male part and the female part comprising a tapered tube connecting portion which is adapted to be inserted into the end of a tube.
EP 0 ~~5 501 13 describes a female coupling element of the Luer-Lock type comprising an outer tubular body which is made of a relatively rigid moulded thermoplastics mafierial and can be connected with a complimentary male coupling element, and an inner sleeve which is made of a softer moulded thermoplastics material which at one end is fitted within the outer body in such a manner that the two parts are freely rotatable relative to each other and at the opposite end comprises a cavity for connection to e.g. a tube.
Furthermore, medical connectors consisting of a single plastics material and manufactured by injection moulding are known.
Such medical connectors comprise a through-going bore, one end of said connector being adapted to be connected with the end of a tube by gluing so as to form a permanent connection and the opposite end comprising a part of a Luer-Lock type connection for connecting the connector to a medical device such as an insulin pump.
Due to the fact that an injection moulding process is a simple manufacturing method, such medical connectors can be manufactured at low costs.
However, these medical connectors suffer from a drawback.
Thus, prior to the use of a medical connector it has to be disinfected which ordinarily is effected by wiping it with a liquid disinfectant such as ethyl alcohol.
Such a treatmenfi may cause stresses in some plastics material to be released during physical strain and may result in the formation of cracks which bring aboufi leaks.
The selection of a plastics material which is resisfianfi to fibs influence of disinfecfianfis may cause another problem, vii. thafi fibs permanent connection of fibs fiube end to fibs connecfior has to be effiecfied by means of a~ hard glue.
The use of a hard glue in confirasfi to a soft glue resulfis in an inflexible connecfiion between fibs tube and fibs connecfior and may resulfi in a leakage.
In the previously known connecfiors composed of two plastics materials, such as those described in EP 0 775 501 B, the two parts have to be made separafiely and be assembled afterwards. This increases the production costs compared to connectors which can be injection moulded in one-piece.
The object of the present invention is to provide a medical connector which can be manufactured in large quantities at low costs and which is more resistant to leakage than the prior art medical connectors.
According to the invention there is provided a medical connector of the above mentioned type having a through-going bore which at one end of the connector comprises a cavity for permanently attaching the end of the tube to the connector and which at least at said end of the connector comprises an inner part and an outer part; the inner and outer parts being integrally connected, the outer part being made from a thermoplastics material which is resistant to changes when subjected to the influence of a disinfectant and the inner part being made from a thermoplastics material which is compatible with a soft glue.
The term integrally connected is to be understood as the two parts are connected in such way that they are unable to rotate independently around the longitudinal axis.
This new type of connectors is easy and cheap to produce. They are resistant to the mandatory disinfection prior to use and they have a flexible but permanent attachment of the tube to the connector.
According to fihe invention there is further provided a method for injection moulding of a connector of the above mentioned type comprising the steps of - injecting a plastics material which is compatible with a soft glue into a mould having a cavity of the desired shape and a core of the desired shape for forming a cavity in the connector for permanently atfiaching an end of a tube - injecting a plastics material which is resistant to changes when subjected to the influence of a disinfectant infix a mould having a cavity of the desired shape, a core for creating a through-going opening - using a part of the surface of the firstly injected plastics material as part of the mould receiving the secondly injected plastics material.
In one embodiment of the invention the connector comprises means for connecting the connector to a medical device such as an insulin pump, said means preferably being in form of a Luer-Lock type, and more preferably the means are capable of receiving the male part of the Luer-Lock type.
In a preferred embodiment the term integrally connected further implies that the two parts are unable to move independently along the length axis.
Preferably the connector comprises means for getting a better hold of the connector, which can be advantageous when connecting or disconnecting the connector to a medical device. Said means can be but are not limited to a groove, a ribbon, a rim, preferably the means are in form of a groove.
Preferably said means are placed in the same end as fihe tube is supposed to be attached.
In another embodiment of the invention the inner part and the outer part of the connector are capable of rocking relative to each other thereby providing a more flexible but still permanent connection to the tube. This reduces the risk of leakage even further.
In a preferred embodiment the cavity of the inner part of the connector has an increasing diameter towards the outer end of the inner part, preferably a part of the cavity has a conical shape. Preferably, the conical part forms an angle of at least 15 degrees relative to the central axis, preferably the angle is between 20 and 25 degrees.
In another embodiment the cavity of the outer part at the end receiving the tube also has an increasing diameter towards the outer end. Preferably at least a part of the cavity of the outer part has a conical shape.
By using a conical-shaped cavity of the inner part and/or a cavity of the outer part with an increasing diameter an even more flexible connection between the connector and the tube can be achieved. Further, the increasing diameter leaves more room for the soft and elastic glue.
In a preferred embodiment the diameter of the cavity of the inner part is 5 adapted to the diameter of the tube supposed to be permanently connected with the connector.
Preferably the connector is constructed in such way that the inner part at least in the area of connection between the connector and the tube is unable to come into contact with the disinfectants. Preferably the plastics material of the inner part is selected exclusively from its gluing properties i.e. it is compatible with a soft glue.
In one embodiment of the invention the delimiting part of the edge is flush with the delimiting edge of the outer part or even broaches there around and encloses portions of the outer faces of the outer part. In this case what matters is that a sealing is provided to prevent the liquid from penetrating from the outside and into the connecting area between the tube and the inner part.
In another embodiment the outer part is moulded in such way that it encloses the outer faces of the inner part so that during wiping with a disinfectant connection between the disinfectant and the inner part of the connector cannot be provided.
The connector with its permanently attached tube is preferably intended for use for infusion kits where the luer lock is mounted to an insulin pump, while the tube as such is connected to a syringe and an infusion part.
In another preferred embodiment the inner part and/or the outer part comprises fasteners for fastening the inner part to the outer part or visa versa, more preferably the inner part has retention devices and the outer part has grooves adapted to receive said retention devices. In an even more preferred embodiment the retention devices are mounted on the outside of the inner part and thereby providing a good retention between the inner part and the outer part ensuring that the inner part cannot be loosened.
In another embodiment the inner part and the outer part are connected and/or held together by means of a glue.
In another preferred embodiment the inner parfi, the glue and an area of the tube are capable of forming an integral chemical connection.
Preferably the soft glue used in the permanenfi connection betv~een the tube and the connector as a minimum has contact to both the tube and the inner ~ 5 part. It is of no consequence whether the glue further has contact to the outer part or not, it is only importanfi that the connection has an inner area which is unable to come into contact with the disinfectant used to wipe the connector prior to use.
In a preferred embodiment the through-going bore of the outer part has a central axis which is axially parallel and coincident with the central axis of the inner part.
In a preferred embodiment both the inner part and the outer part are made of a thermoplastic material. In a more preferred embodiment the inner part is made of an amorphous plastics material, preferably with a molecular structure in which the chains are positioned randomly.
In a preferred embodiment the inner part is made of ABS. ABS is made of the monomer components acrylic nitrite, butadiene and styrene. Each of the three structural units adds valuable properties to the material. Acrylic nitrite is responsible for the resistance and dimensional stability in heat. Butadiene equips the material with tenacity and makes it resistant to impacts, while styrene serves to ensure the rigidity of the material and easy processability.
ABS tolerates a number of acids, bases and oils with the proviso, however, that the level of internal stresses is very low. There are a number of solvents that can dissolve ABS. Other suitable amorphous plastics materials include e.g. polycarbonate, polystyrene, acrylic plastics, poly-methyl-methacrylate and PVG.
In another preferred embodiment the outer part is made of a plastics material also being a thermoplastics material and composed of at least one partially plastics material, preferably a polypropylene is used. Polypropylene is a partially crystalline plastics material in which the molecule chains are located in parallel with each other and form rather closely packed areas, the so-~ 5 called crystallites. Polypropylene is a thermoplastics material with an attractive balance between fihermal and chemical resistance and good mechanical and electrical properties. Furthermore, polypropylene is immune to bacteria and fungi. Additionally polypropylene is a plastics material having a very wide-ranging resistance to chemicals. It is resistant to salts, acids, ~0 bases (inorganic) and alcohols and some oils. In principle, it is the crystallite that is decisive to the resistance to chemicals. Also other materials can be used for the outer part e.g. polyamide, polyethylene, poly-ethylene-ether-ketone (PEEK).
~5 A crystalline plastics material is characterised in that the molecules are situated closely adjoining each other whereby the intermolecular forces act more strongly and more energy is to be supplied in order to overcome it. In practice this means that crystalline plastics/partially crystalline plastics generally have a higher temperature of vitrification and a higher melting point 30 than amorphous materials. The crystalline areas in the material have a distributing effect on light and therefore crystalline and partially crystalline plastics have a milky appearance.
A thermoplastics material has the characteristic feature that it exhibits three different, more or less sharply delimiting state areas as a function of the temperature, viz. a solid state, a rubber elastic state and a viscous state.
Upon heating the material becomes soft and assumes a rather more solid structure upon cooling and, in principle, it is possible to shape it several times.
The following physical, mechanical properties apply to a soft glue versus a hard glue.
~~ft glue Hard Tae Extension at 120/~-240/~0/~-50/~
break Hardness shore ~25-~60 ~65-~90 ~
In a preferred embodiment the connector is adapted to receive means for supporting the attachment of the tube. Said means are suitable for securing the tube to the connector until the glue is hardened.
~uring attachment of the tube to the connector it is preferred to have a final hardening after the glue is mounted between the connector and the tube.
Further it is preferred that the connector is adapted to firap and secure the tube until the glue has set.
The invention also relates to an infusion unit manufactured from the connector and wherein the end opposite to the tube is connected to an insulin pump by means of a luer-lock and wherein a soft glue is used to connect the tube to the connector.
In a preferred method of producing said connectors a plastics material which is compatible with a soft glue is injected into the mould under a suitable pressure for providing the inner part, subsequently under a suitable second pressure a plastics material being resistant to changes when subjected to the influence of a disinfectant is injected into the mould. Following such moulding of the connector, said moulding taking place e.g. in accordance with principles like the ones given in patent f'Jo. W~ 00/73040 and W~ 93/35303, an opening of the mould takes place and the connectors are ejected from their cores. ~ptionally a subsequent assembly process between the connector and a tube takes place as described above by means of a soft glue.
15' In the following a preferred embodiment of the invention will be described with reference to the figures.
Figures 1A-~ show an example of a connecting element according fio the ~0 invention seen from two different sides;
Figure 2 is a sectional view along II-II in Figure 1A;
Figure 3 is a sectional view of the outer part in detailed form;
Figure 4 is a sectional view of the inner part in detailed form;
Figure 5 shows the disclosures of Figure 2 with a plastics tube mounted in the inner part.
Figures 1A and 1 B show a connector 1, seen from the side in a first position and turned by 90°. The connector, see also Figure 2, comprises an outer part 2 which is preferably made of a thermoplastics material that is chemically resistant to disinfectant such as ethyl alcohol. The outer part comprises an 5 end 4 for receiving a tube and an end 5 for connecting to a medical device such as an insulin pump. The end 4 for receiving a tube comprises a cavity 6 as it is also seen in the sectional view in Figure 2.
The end 5 for connecting to a medical device comprises a luer lock 21 in 10 which a male luer-lock is preferably used. Finally the end 5 comprises an external double-thread 29 for being mounted to preferably an insulin pump.
The outer shape of the connector 1 is such that it is essentially cylindrically shaped, beat wherein the end 4~ for receiving fihe tube has a narrowed portion for providing an oval narrowing area 23. This serves to improve the gripping around the connector° 1 during handling thereof. The outer part 2 has an outer essentially plane upper delimiting face 20. The distance from this and down to the lower delimiting face 34 is within the range 17 mm.
Figure 2 is a sectional ~siew wherein the joining between the two elements that constitute the connecfior 1 vii. the oufier part 2 and the inner part 9 will appear. The outer part is manufactured such that there is liquid communication throughout its entire passage and it comprises axially a passage throughout its entire interior, wherein, in its end 5, it has such shape that it forms a leer lock 21. From said luer lock 21 an axial opening 3 fio the cavity 6 is provided. The central axis of the opening 3 is axially parallel and coinciding with a through-going opening 10 provided in the inner part 9. In the opposite end of the inner part 9 there is a section called the connector part 32 for the tube which is configured with side faces that diverge outwards towards an upper delimiting face 17, where said delimiting face 17 is of plane configuration.
In the area between the tube connector part 32 and the otherwise cylindrically shaped opening 10 the interior area 35 and a further essentially conically shaped connecting area that may also constitute a part of the tube connector part and serve as glue reservoir are situated. The interior area is situated so that the glue ensuring connection between the tube and the inner part cannot be in liquid communication with the exterior of the connector. The inner part 9 is located so that its upper delimiting face17 is located at a distance from the upper delimiting face 20 of the outer part 2 as such. It should further be mentioned that the inner part 9 has on its outer circumference retention devices 15 e.g. in form of studs or wings that serve as undercuts whereby good gripping is ensured during moulding between the inner part 9 and the outer part 2.
The outer part 2 will be described with reference to Figure 3. The outer part comprises as mentioned an essentially oufier cylindrically shaped sleeve having essentially three cavities; a cavity in the end 5 comprising a lust lock 21 and preferably a male lust lock from which there is connection via a central opening 3 to the cavity 6 in the end of the outer part 2 for attaching the tube which interior faces are shaped to be essentially congruent with the outer faces of the inner part. The outer part 2 is manufactured from a chemically resistant material 13, whereby no stresses are released when it is wiped with e.g. ethyl alcohol.
The inner part 9 will be described with reference to Figure ~.. It also comprises a sleeve-like construction, its outer walls 14 being essentially cylindrical with various pouches/retention devices mounted thereon for providing good retention between the inner part and the outer part.
The cavity of the inner part comprises essentially four areas, viz. a through-going opening 10 in communication with the inner area 35 being an essentially cylindrical area having a length of essentially about 3 mm and with a somewhat larger diameter than the opening 10; a conical area of about 1 mm forming the connection between the inner area and the tube connector part 32; and said tube connector part constituting the upper part of the inner part 9. This tube connector part is configured such that the walls diverge outwards towards the upper delimiting face 17 of the inner part 9 said face 17 being of essentially plane configuration. As mentioned the outer walls of the inner part also comprise retention devices 15.
The connection between the tube and the inner part including the tube connector part 32 that may also be an area where the glue bonds and seals the remaining entrance, will be described in further defiail with reference to Figure 5. It shows the joint between a connector 1 and a tube 24, wherein a secfiion has been made fihrough the connecting elemenfi and the tubular elemenfi. A luer-lock is shown and opposite fio fihafi the tubular elemenfi is located in fibs inner park 9 of the connecting elemenfi corresponding to the inner area 35. It is nofied in this content fihafi fibs tube connector part 32 is situafied so thafi its upper delimiting face is located at a disfiance from the upper delimitafiing face 20 of fibs outer park. lNhen the fiube seines fibs tube connecfior park 32, and wherein - between the outer face of fibs fiube 2~ and fibs inner face of the tube connecfior park 32 - attachmenfi means 3 are located in the form of a soft glue, the risk of chemicals, if any, used for wiping the outer face of the outer part penetrating downwards to the inner area 35 of the inner part as such will be small due, on the one hand to said distance and, on the other hand, to the sealing properties of the glue. This is essential since the inner park is manufactured precisely from a plastics material fihat provides good connection to the tube when a soft glue is selected. This plastics material is not resistant to the material used for wiping.
Conversely, a material that tolerates wiping with chemicals, including e.g. ethyl alcohol can be used for the outer part.
The outer part 2 will be described with reference to Figure 3. The outer part comprises as mentioned an essentially oufier cylindrically shaped sleeve having essentially three cavities; a cavity in the end 5 comprising a lust lock 21 and preferably a male lust lock from which there is connection via a central opening 3 to the cavity 6 in the end of the outer part 2 for attaching the tube which interior faces are shaped to be essentially congruent with the outer faces of the inner part. The outer part 2 is manufactured from a chemically resistant material 13, whereby no stresses are released when it is wiped with e.g. ethyl alcohol.
The inner part 9 will be described with reference to Figure ~.. It also comprises a sleeve-like construction, its outer walls 14 being essentially cylindrical with various pouches/retention devices mounted thereon for providing good retention between the inner part and the outer part.
The cavity of the inner part comprises essentially four areas, viz. a through-going opening 10 in communication with the inner area 35 being an essentially cylindrical area having a length of essentially about 3 mm and with a somewhat larger diameter than the opening 10; a conical area of about 1 mm forming the connection between the inner area and the tube connector part 32; and said tube connector part constituting the upper part of the inner part 9. This tube connector part is configured such that the walls diverge outwards towards the upper delimiting face 17 of the inner part 9 said face 17 being of essentially plane configuration. As mentioned the outer walls of the inner part also comprise retention devices 15.
The connection between the tube and the inner part including the tube connector part 32 that may also be an area where the glue bonds and seals the remaining entrance, will be described in further defiail with reference to Figure 5. It shows the joint between a connector 1 and a tube 24, wherein a secfiion has been made fihrough the connecting elemenfi and the tubular elemenfi. A luer-lock is shown and opposite fio fihafi the tubular elemenfi is located in fibs inner park 9 of the connecting elemenfi corresponding to the inner area 35. It is nofied in this content fihafi fibs tube connector part 32 is situafied so thafi its upper delimiting face is located at a disfiance from the upper delimitafiing face 20 of fibs outer park. lNhen the fiube seines fibs tube connecfior park 32, and wherein - between the outer face of fibs fiube 2~ and fibs inner face of the tube connecfior park 32 - attachmenfi means 3 are located in the form of a soft glue, the risk of chemicals, if any, used for wiping the outer face of the outer part penetrating downwards to the inner area 35 of the inner part as such will be small due, on the one hand to said distance and, on the other hand, to the sealing properties of the glue. This is essential since the inner park is manufactured precisely from a plastics material fihat provides good connection to the tube when a soft glue is selected. This plastics material is not resistant to the material used for wiping.
Conversely, a material that tolerates wiping with chemicals, including e.g. ethyl alcohol can be used for the outer part.
It should be noted with regard to soft glue that it is inherently more flexible than hard glue. A soft glue is used precisely in order to enable the plastic tube to retain its flexibility in the in-use situation.
Claims (12)
1. A medical connector for connecting a tube with a medical device and having an upper end, a lower end and a through-going opening which at the upper end of the connector comprises a cavity for permanently attaching the end of the tube to the connector and which at least at said end of the connector comprises an inner part having an upper delimiting surface and an outer part having an upper delimiting surface, the inner and outer parts being integrally connected, the outer part being made from a thermoplastic material which is resistant to the influence of a disinfectant and the inner part being made from a thermoplastic material which is compatible with a soft glue wherein the upper delimiting surface of the outer part projects proud of the upper delimiting surface of the inner part and:
(i) the tube is attached permanently in the cavity of the inner part with a soft glue, wherein the glue is located between the outer surface of the tube and an essentially conically shaped connecting area of the cavity;
(ii) the inner part and outer part are connected in such a way that they are unable to rotate around the longitudinal axis; and (iii) the inner part is unable to come in contact with disinfectants used to wipe the connector prior to use.
(i) the tube is attached permanently in the cavity of the inner part with a soft glue, wherein the glue is located between the outer surface of the tube and an essentially conically shaped connecting area of the cavity;
(ii) the inner part and outer part are connected in such a way that they are unable to rotate around the longitudinal axis; and (iii) the inner part is unable to come in contact with disinfectants used to wipe the connector prior to use.
2. A medical connector according to claim 1, wherein the thermoplastic material for the inner part is an amorphous plastic material.
3. A medical connector according to claim 1, wherein the thermoplastic material for the inner part is an acrylonitrile butadiene styrene (ABS) material.
4. A medical connector according to claim 1, wherein the thermoplastic material for the outer part is an at least partially crystalline material.
5. A medical connector according to claim 4, wherein the thermoplastic material for the outer part is a polypropylene.
6. A medical connector according to claim 1, wherein the outer walls of the inner part are sheathed by the outer part and comprise retention devices.
7. A medical connector according to claim 1, wherein the inner part is an essentially rotationally symmetrical body with a rotationally symmetrical through-going opening.
8. A medical connector according claim 1, wherein the cavity for permanently attaching the end of the tube has an increasing diameter towards the upper end.
9. A medical connector according to claim 8, wherein the generatrix of the conically shaped connecting area forms an angle of at least 15 degrees relative to a central axis.
10. A medical connector according claim 1, wherein the outer part at the upper end has a cavity with a diameter increasing towards the upper delimiting surface.
11. A medical connector according to claim 1, wherein the connector comprises a luer-lock.
12. An infusion device comprising a connector according to claim 1, wherein the lower end of the connector is connected to an insulin pump and the upper end is connected to a plastic tube.
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DKPA200300207 | 2003-02-12 | ||
| DKPA200300207 | 2003-02-12 | ||
| US10/437,488 US20040155457A1 (en) | 2003-02-12 | 2003-05-13 | Connecting element comprising a first body and a method for injection moulding a connecting element |
| US10/437,488 | 2003-05-13 | ||
| PCT/DK2004/000100 WO2004071568A1 (en) | 2003-02-12 | 2004-02-12 | A medical connector and a method of injection moulding such a connector |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2555464A1 CA2555464A1 (en) | 2004-08-26 |
| CA2555464C true CA2555464C (en) | 2011-11-08 |
Family
ID=32870665
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2555464A Expired - Fee Related CA2555464C (en) | 2003-02-12 | 2004-02-12 | A medical connector and a method of injection moulding such a connector |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US7455325B2 (en) |
| EP (1) | EP1599249B1 (en) |
| AT (1) | ATE346646T1 (en) |
| CA (1) | CA2555464C (en) |
| DE (1) | DE602004003477T2 (en) |
| DK (1) | DK1599249T3 (en) |
| WO (1) | WO2004071568A1 (en) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2007143813A (en) * | 2005-11-28 | 2007-06-14 | Nippon Sherwood Medical Industries Ltd | Medical stopcock |
| FR2900817B1 (en) | 2006-05-12 | 2008-12-19 | Gambro Lundia Ab | MEDICAL BANDAGE FOR AN IMPLANTED TUBE IN A PATIENT, AND METHOD FOR APPLYING THE BANDAGE TO A PATIENT'S SKIN |
| US9192449B2 (en) | 2007-04-02 | 2015-11-24 | C. R. Bard, Inc. | Medical component scrubbing device with detachable cap |
| US8336152B2 (en) | 2007-04-02 | 2012-12-25 | C. R. Bard, Inc. | Insert for a microbial scrubbing device |
| WO2009097327A1 (en) * | 2008-01-28 | 2009-08-06 | Colder Products Company | Quick connect/disconnect coupling assemblies |
| US8353876B2 (en) * | 2008-01-30 | 2013-01-15 | Becton, Dickinson And Company | Occlusion resistant catheters |
| US8696820B2 (en) * | 2008-03-31 | 2014-04-15 | Bard Access Systems, Inc. | Method of removing a biofilm from a surface |
| US8372057B2 (en) * | 2008-10-10 | 2013-02-12 | Coeur, Inc. | Luer lock adapter |
| CN102448502B (en) | 2009-04-01 | 2015-06-03 | C·R·巴德股份有限公司 | Microbial scrubbing device |
| EP2422837B1 (en) * | 2009-04-23 | 2014-12-24 | JMS Co., Ltd. | Medical connector structure |
| US20120078215A1 (en) * | 2010-09-28 | 2012-03-29 | Tyco Healthcare Group Lp | Two-piece vial transfer needle assembly |
| US9339640B2 (en) * | 2011-02-11 | 2016-05-17 | Carefusion 303, Inc. | Connector for multiple sizes of tubing |
| WO2012151558A2 (en) | 2011-05-04 | 2012-11-08 | Gallagher Anthony David | Coupling for pvc piping sections |
| WO2014000056A1 (en) * | 2012-06-29 | 2014-01-03 | University Of South Australia | Fluid connection ports |
| US9750928B2 (en) | 2013-02-13 | 2017-09-05 | Becton, Dickinson And Company | Blood control IV catheter with stationary septum activator |
| US9675793B2 (en) | 2014-04-23 | 2017-06-13 | Becton, Dickinson And Company | Catheter tubing with extraluminal antimicrobial coating |
| US10376686B2 (en) | 2014-04-23 | 2019-08-13 | Becton, Dickinson And Company | Antimicrobial caps for medical connectors |
| US9789279B2 (en) | 2014-04-23 | 2017-10-17 | Becton, Dickinson And Company | Antimicrobial obturator for use with vascular access devices |
| US10232088B2 (en) | 2014-07-08 | 2019-03-19 | Becton, Dickinson And Company | Antimicrobial coating forming kink resistant feature on a vascular access device |
| US10493244B2 (en) | 2015-10-28 | 2019-12-03 | Becton, Dickinson And Company | Extension tubing strain relief |
| DE102016101911A1 (en) | 2016-02-03 | 2017-08-03 | B. Braun Avitum Ag | Medical clutch and medical system with a medical clutch |
| US10557573B2 (en) * | 2016-11-04 | 2020-02-11 | United Technologies Corporation | Feed through seals and fittings |
| EP3703801B1 (en) | 2017-11-03 | 2022-10-05 | Hollister Incorporated | Methods of bonding components to polymeric substrates |
| DE102019219245A1 (en) * | 2019-12-10 | 2021-06-10 | B. Braun Melsungen Aktiengesellschaft | Connector, system with connector and hose line as well as method for connecting a connector to a hose line |
| JP2023056709A (en) * | 2021-10-08 | 2023-04-20 | 株式会社ジェイ・エム・エス | Medical connector with tube |
Family Cites Families (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3469579A (en) * | 1967-05-05 | 1969-09-30 | Becton Dickinson Co | Catheter needle |
| GB1437352A (en) * | 1972-12-11 | 1976-05-26 | British Wire Products Ltd | Joints or connectors |
| US4346704A (en) | 1980-09-09 | 1982-08-31 | Baxter Travenol Laboratories, Inc. | Sleeve valve for parenteral solution device |
| DE3150052C2 (en) * | 1981-12-17 | 1985-02-21 | Sterimed Gesellschaft für medizinischen Bedarf mbH, 6600 Saarbrücken | Catheter for catheterizing central veins |
| US5688254A (en) * | 1983-01-24 | 1997-11-18 | Icu Medical, Inc. | Medical connector |
| US5199947A (en) * | 1983-01-24 | 1993-04-06 | Icu Medical, Inc. | Method of locking an influent line to a piggyback connector |
| US4790829A (en) * | 1983-08-24 | 1988-12-13 | Russell Bowden | Reusable injection catheter |
| ZA85151B (en) | 1984-01-25 | 1985-08-28 | Squibb & Sons Inc | Quick disconnect tube coupling |
| JPS61113468A (en) * | 1984-11-06 | 1986-05-31 | テルモ株式会社 | Medical appliances |
| JPS61113467A (en) * | 1984-11-06 | 1986-05-31 | テルモ株式会社 | Medical appliances |
| US4693710A (en) * | 1985-03-13 | 1987-09-15 | Sherwood Medical Company | Tube and fitting assembly and method of making same |
| SE462538B (en) * | 1986-06-06 | 1990-07-09 | Gambro Ab | CONNECTOR PARTS HOSE OR CLEAR HOSE |
| US4874377A (en) * | 1988-05-26 | 1989-10-17 | Davis Newgard Revocable Family Living Trust | Self-occluding intravascular cannula assembly |
| US4878900A (en) * | 1988-07-27 | 1989-11-07 | Sundt Thoralf M | Surgical probe and suction device |
| NL8902307A (en) * | 1989-09-14 | 1991-04-02 | Cordis Europ | CATHETER. |
| US5586977A (en) * | 1990-01-26 | 1996-12-24 | C.R. Bard, Inc. | Quick disconnect fitting for coupling interchangeable probe tip to laparoscopic instrument |
| US5380301A (en) * | 1992-07-10 | 1995-01-10 | Sherwood Medical Company | Catheter/hub strain relief and method of manufacture thereof |
| GB9514011D0 (en) | 1995-07-10 | 1995-09-06 | Squibb & Sons Inc | Tube coupling |
| US5611576A (en) * | 1995-11-24 | 1997-03-18 | Industrie Borla Spa | Female coupling element for haemodialysis medical equipment |
| US6017319A (en) * | 1996-05-24 | 2000-01-25 | Precision Vascular Systems, Inc. | Hybrid tubular guide wire for catheters |
| US5782505A (en) * | 1996-08-29 | 1998-07-21 | Becton, Dickinson And Company | Catheter adapter assembly |
| US5735813A (en) * | 1996-10-23 | 1998-04-07 | Danron, Inc. | Double lumen introducing needle |
| DE69835910T2 (en) | 1997-01-29 | 2007-05-03 | Jes Tougaard Gram | Mold for making a composite article |
| US5803509A (en) * | 1997-04-28 | 1998-09-08 | Adams; Robert D. | Line connector lock |
| US5997562A (en) * | 1997-06-13 | 1999-12-07 | Percusurge, Inc. | Medical wire introducer and balloon protective sheath |
| DE29712676U1 (en) * | 1997-07-17 | 1997-11-13 | Rycyk Manfred | Kink protection for catheters |
| JPH11313896A (en) * | 1998-05-01 | 1999-11-16 | Kawasumi Lab Inc | Female connector |
| US6332874B1 (en) * | 1998-08-28 | 2001-12-25 | C.R. Bard, Inc. | Coupling and stabilization system for proximal end of catheter |
| US6273478B1 (en) * | 1999-03-30 | 2001-08-14 | The Regents Of The University Of California | Microfluidic interconnects |
| AU4537800A (en) | 1999-05-17 | 2000-12-18 | Jes Tougaard Gram | Mould with turnable middle section |
| US6260890B1 (en) * | 1999-08-12 | 2001-07-17 | Breg, Inc. | Tubing connector |
| US6575959B1 (en) * | 1999-12-27 | 2003-06-10 | Scimed Life Systems, Inc. | Catheter incorporating an insert molded hub and method of manufacturing |
| US6651956B2 (en) * | 2002-01-31 | 2003-11-25 | Halkey-Roberts Corporation | Slit-type swabable valve |
| US20040100093A1 (en) * | 2002-11-21 | 2004-05-27 | Leigh-Monstevens Keith V. | Co-extruded tube with molded connector |
| WO2005025661A2 (en) * | 2003-09-11 | 2005-03-24 | Cook Incorporated | Catheter having an overmolded hub |
| US20060259012A1 (en) * | 2005-05-13 | 2006-11-16 | Tri-State Hospital Supply Corporation | PIV high pressure infusion set |
-
2004
- 2004-02-12 AT AT04710340T patent/ATE346646T1/en not_active IP Right Cessation
- 2004-02-12 CA CA2555464A patent/CA2555464C/en not_active Expired - Fee Related
- 2004-02-12 DK DK04710340T patent/DK1599249T3/en active
- 2004-02-12 DE DE602004003477T patent/DE602004003477T2/en not_active Expired - Lifetime
- 2004-02-12 EP EP04710340A patent/EP1599249B1/en not_active Expired - Lifetime
- 2004-02-12 WO PCT/DK2004/000100 patent/WO2004071568A1/en active IP Right Grant
- 2004-12-29 US US11/024,892 patent/US7455325B2/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| DE602004003477D1 (en) | 2007-01-11 |
| CA2555464A1 (en) | 2004-08-26 |
| US7455325B2 (en) | 2008-11-25 |
| DK1599249T3 (en) | 2007-04-02 |
| DE602004003477T2 (en) | 2007-10-04 |
| ATE346646T1 (en) | 2006-12-15 |
| EP1599249A1 (en) | 2005-11-30 |
| WO2004071568A1 (en) | 2004-08-26 |
| EP1599249B1 (en) | 2006-11-29 |
| US20050142945A1 (en) | 2005-06-30 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CA2555464C (en) | A medical connector and a method of injection moulding such a connector | |
| US8640725B2 (en) | Connector for transferring fluid and method of use | |
| US4588402A (en) | Connector for medical tubing and medical solution bag device using the connector | |
| AU2002320957B2 (en) | A method of producing a catheter and a catheter | |
| US20040155457A1 (en) | Connecting element comprising a first body and a method for injection moulding a connecting element | |
| JP5643369B2 (en) | Positive movement stopper for prefilled syringe | |
| ES2375013T3 (en) | MEDICAL CONNECTOR | |
| US10099032B2 (en) | Catheter with integrated insertion aid | |
| AU2011351446B2 (en) | Catheter with integrated insertion aid | |
| US20180021519A9 (en) | Plunger Covers and Plungers For Use In Syringes | |
| US20120316536A1 (en) | Set of Easily Cleanable Connectors For A Liquid Circuit | |
| US10716927B2 (en) | Extrudable tubing for delivery of medicinal fluids | |
| US7947146B2 (en) | Plastic carpule and method of manufacture | |
| CA2155282A1 (en) | Valved prn adapter for infusion devices | |
| EP3086825B1 (en) | Medical measuring system and method for the production of the measurement system | |
| US20100280370A1 (en) | Syringe plunger | |
| WO2015180892A1 (en) | Drip chamber for administering a medical fluid | |
| KR20150095703A (en) | Assembly for medical use for administering a product to a patient | |
| KR200429645Y1 (en) | Port of medical plastic bags | |
| CN212631334U (en) | Infusion extension subassembly and infusion subassembly | |
| JP2001046516A (en) | Outer lure adapter |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| MKLA | Lapsed |
Effective date: 20140212 |